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Title
Japanese:Transition-Metal-Catalyzed Cyclization of Alkynals via Oxametallacycle Intermediates. 
English:Transition-Metal-Catalyzed Cyclization of Alkynals via Oxametallacycle Intermediates. 
Author
Japanese: Ken Tanaka, Yuki. Tajima.  
English: Ken Tanaka, Yuki. Tajima.  
Language English 
Journal/Book name
Japanese:European Journal of Organic Chemistry 
English:European Journal of Organic Chemistry 
Volume, Number, Page Vol. 2012    No. 20    pp. 3715-3725
Published date 2012 
Publisher
Japanese:Wiley-VCH Verlag GmbH & Co. KGaA 
English:Wiley-VCH Verlag GmbH & Co. KGaA 
Conference name
Japanese: 
English: 
Conference site
Japanese: 
English: 
DOI https://doi.org/10.1002/ejoc.201200098
Abstract A review. The transition-metal-catalyzed cyclization of alkynals via oxametallacycle intermediates is a useful method for the stereoselective synthesis of cyclic allylic alc. derivs. The reductive cyclization reactions are catalyzed by titanium and nickel complexes using organosilanes, organoboranes, and organozincs as reducing agents. The alkylative, arylative, and alkenylative cyclization reactions are catalyzed by nickel complexes using organozincs and alkenylzirconiums. On the other hand, the recently developed rhodium-catalyzed reductive cyclization reactions of alkynals allow the use of dihydrogen as a reducing agent without the use of organometalloid and organometallic reagents. Furthermore, very recently, the rhodium-catalyzed acylative cyclization reactions of alkynals were accomplished by using aldehydes and acyl phosphonates as acylating reagents. Importantly, the use of the rhodium catalysts realized the enantioselective cyclization reactions of alkynals with excellent levels of enantioselection. [on SciFinder(R)]

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