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Title
Japanese:Enantioselective helicene synthesis by rhodium-catalyzed [2+2+2] cycloadditions. 
English:Enantioselective helicene synthesis by rhodium-catalyzed [2+2+2] cycloadditions. 
Author
Japanese: Ken Tanaka, Yuki Kimura, Koichi. Murayama.  
English: Ken Tanaka, Yuki Kimura, Koichi. Murayama.  
Language English 
Journal/Book name
Japanese:Bulletin of the Chemical Society of Japan 
English:Bulletin of the Chemical Society of Japan 
Volume, Number, Page Vol. 88    No. 3    pp. 375-385
Published date 2015 
Publisher
Japanese:Chemical Society of Japan 
English:Chemical Society of Japan 
Conference name
Japanese: 
English: 
Conference site
Japanese: 
English: 
DOI https://doi.org/10.1246/bcsj.20140291
Abstract This review presents highly enantioselective synthesis of functionalized helicenes and helicene-like mols. have been achieved via rhodium-catalyzed [2+2+2] cycloaddn. reactions. The rhodium-catalyzed enantioselective intramol. [2+2+2] cycloaddn. of 2-naphthol-linked triynes afforded [7]helicene-like mols. in good yields and ee values. The more sterically encumbered reaction, the rhodium-catalyzed enantioselective double intramol. [2+2+2] cycloaddn. of a 2-naphthol-linked hexayne, also proceeded to give a [11]helicene-like mol. with high ee value, although the product yield was low. Not only intramol. cycloaddn. reactions but also intermol. ones were accomplished by combinations of electron-rich tetraynes and electron-poor diynes to give [7]- and [9]helicene-like mols. and [7]helicenes in varying yields and ee values. [on SciFinder(R)]

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