In this paper, throughput performance of MIMO-OFDM system in real residential home environment was evaluated by using wideband MIMO channel measurement data. Computer simulations were carried out to compare the performance of MIMO-OFDM systems with various detection methods, i.e. MMSE, VBLAST, QRM-MLD and SVD-MIMO, in addition to that of the SISO-OFDM system. The results showed that the SVD-MIMO transmission can provide the highest average and outage throughput under the assumption of perfect CSI feedback. On the other hand, QRM-MLD yielded the best performance among the systems without CSI available at the transmitter. It was also found that the outage throughput performance of MMSE and VBLAST degrades severely due to the existence of spatial correlation in the real home environment.