"Matthew N. Saxton,Tatsuya Morisaki,Diego Krapf,Hiroshi Kimura,Timothy J. Stasevich","Live-cell imaging uncovers the relationship between histone acetylation, transcription initiation, and nucleosome mobility",,"Science Advances",,,,,2023,Oct.
"足立 惇弥,福嶋 俊明,小田 春佳,菅井 祥加,佐藤 浩平,木村 宏,金原 数","粘度応答性蛍光プローブの開発と生細胞内における応答性","第17回バイオ関連化学シンポジウム",,,,,,2023,Sept.
"Hiroshi Ochiai,Hiroaki Ohishi,Yuko Sato,Hiroshi Kimura","Organization of transcription and 3D genome as revealed by live-cell imaging",,"Current Opinion in Structural Biology",,,,,2023,Aug.
"大室有紀,北口哲也,上田宏,木村宏","YFP断片とintrabodyを利用した生細胞内におけるエピジェネティクス変化の観察法構築","第45回日本分子生物学会年会","第16回日本エピジェネティクス研究会年会 要旨集",,,,,2023,June
"Haruka Oda,Yuko Sato,Shigehiro A. Kawashima,Yusuke Fujiwara,M?t? P?lfy,Edlyn Wu,Nadine L. Vastenhouw,Motomu Kanai,Hiroshi Kimura","Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo",,"Biology Open",,,,,2023,May
"Watanya Trakarnphornsombat,Hiroshi Kimura","Live-cell tracking of γ-H2AX kinetics reveals the distinct modes of ATM and DNA-PK in the immediate response to DNA damage",,"Journal of Cell Science",,,,,2023,Apr.
"Junya Adachi,Haruka Oda,Toshiaki Fukushima,Beni Lestari,Hiroshi Kimura,Hiroka Sugai,Kentaro Shiraki,Rei Hamaguchi,Kohei Sato,Kazushi Kinbara","Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection",,"Analytical Chemistry",,,,,2023,Mar.
"Fumiaki Nakamura,Hiroshi Kimura,Nobuhiro Fusetani,Yoichi Nakao","Two Onnamide Analogs from the Marine Sponge Theonella conica: Evaluation of Geometric Effects in the Polyene Systems on Biological Activity",,"Molecules",,,,,2023,Mar.
"足立 惇弥,小田 春佳,福嶋 俊明,菅井 祥加,佐藤 浩平,木村 宏,金原 数","水溶性蛍光プローブの生細胞内における粘度応答性とメラノソームの可視化","日本化学会第103春季年会",,,,,,2023,Mar.
"Hiroki Ozawa,Azusa Kambe,Kodai Hibi,Satoshi Murakami,Akira Oikawa,Tetsuya Handa,Katsunori Fujiki,Ryuichiro Nakato,Katsuhiko Shirahige,Hiroshi Kimura,Nobuaki Shiraki,Shoen Kume","Transient Methionine Deprivation Triggers Histone Modification and Potentiates Differentiation of Induced Pluripotent Stem Cells",,"Stem Cells",,,,,2023,Mar.
"Junya Adachi,Haruka Oda,Toshiaki Fukushima,Beni Lestari,Hiroshi Kimura,Hiroka Sugai,Kentaro Shiraki,Rei Hamaguchi,Kohei Sato,Kazushi Kinbara","Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection",,"Analytical Chemistry",,"  95",,"  5196?5204",2023,Mar.
"Misako Tanaka,Hiroyuki Harada,Hiroshi Kimura","The role of H3K9me3 in oral squamous cell carcinoma",,"Biochemical and Biophysical Research Communications",,,,,2023,Jan.
"Ksenia Kuznetsova,No?mie M. Chabot,Martino Ugolini,Edlyn Wu,Manan Lalit,Haruka Oda,Yuko Sato,Hiroshi Kimura,Florian Jug,Nadine Vastenhouw","Nanog organizes transcription bodies",,"Current Biology",,"Vol. 33","No. 1","pp. 164-173.e5",2023,Jan.
"Fukuda, Kei,Shimi, Takeshi,Shimura, Chikako,Ono, Takao,Suzuki, Takehiro,Onoue, Kenta,Okayama, Satoko,Miura, Hisashi,Hiratani, Ichiro,Ikeda, Kazuho,Okada, Yasushi,Dohmae, Naoshi,Yonemura, Shigenobu,Inoue, Azusa,Kimura, Hiroshi,Shinkai, Yoichi,Hiroshi Kimura","Epigenetic plasticity safeguards heterochromatin configuration in mammals",,"Nucleic Acids Research",,,,,2023,
"Nishino, Miyu,Imaizumi, Hiromasa,Yokoyama, Yuhki,Katahira, Jun,Kimura, Hiroshi,Matsuura, Nariaki,Matsumura, Miki,Hiroshi Kimura","Histone methyltransferase SUV39H1 regulates the Golgi complex via the nuclear envelope-spanning LINC complex",,"Plos One",,,,,2023,
"Hiroaki Ohishi,Seiru Shimada,Satoshi Uchino,Jieru Li,Yuko Sato,Manabu Shintani,owada hitoshi,Yasuyuki Ohkawa,Alexandros Pertsinidis,Takashi Yamamoto,Hiroshi Kimura,Hiroshi Ochiai","STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity",,"Nature Communications",,"Vol. 13","No. 1",,2022,Dec.
"Ksenia Kuznetsova,Noemie M. Chabot,Martino Ugolini,Edlyn Wu,Manan Lalit,Haruka Oda,Yuko Sato,Hiroshi Kimura,Florian Jug,Nadine L. Vastenhouw","Nanog organizes transcription bodies",,"Current Biology",,"Vol. 33","No. 1","pp. 164-173.e5",2022,Dec.
"Yuko Sato,Hiroshi Kimura","Transcriptional regulation and chromatin modifications during zebrafish zygotic genome activation.","第45回日本分子生物学会年会",,,,,,2022,Dec.
"Yohei Kono,Stephen A. Adam,Yuko Sato,Karen L. Reddy,Yixian Zheng,Ohad Medalia,Robert D. Goldman,Hiroshi Kimura,Takeshi Shimi","Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS",,"Journal of Cell Biology",,,,,2022,Dec.
"Naoki Kamiya,Kazuki Kuramoto,Kento Takishima,Tatsuya Yumoto,Haruka Oda,Takeshi Shimi,Hiroshi Kimura,Michio Matsushita,Satoru Fujiyoshi","Superfluid helium nanoscope insert with millimeter working range",,"Review of Scientific Instruments",,"Vol. 93",,"pp. 103703",2022,Oct.
"Yohei Kono,Stephen A. Adam,Yuko Sato,Karen L. Reddy,Yixian Zheng,Ohad Medalia,Robert D. Goldman,Hiroshi Kimura,Takeshi Shimi","Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS",,"J Cell Biol",,"Vol. 221","No. 12","  e202201024",2022,Oct.
"Yuko Sato,Yuma Ito,Satoshi Uchino,Makio Tokunaga,Hiroshi Kimura","Chromatin mobility of X-linked loci and its epigenetic regulation","第60回日本生物物理学会年会",,,,,,2022,Sept.
"上田 宏,DAI YANCEN,佐藤 優子,朱 博,北口 哲也,木村 宏,Farid J. Ghadessy","生細胞内タンパク質の動態観察とそれによる細胞分別が可能な蛍光抗体プローブIntra Q-bodyの構築",,"第16回バイオ関連化学シンポジウム 要旨集",,,,,2022,Sept.
"足立惇弥,福嶋 俊明,小田 春佳,菅井 祥加,佐藤 浩平,木村 宏,金原 数","非TICT型粘度応答性蛍光プローブの開発と生細胞イメージングへの適用","2022年光化学討論会",,,,,,2022,Sept.
"伊藤 由馬,木村 宏","先端技術と理論で迫るクロマチン機能の理解","第60回日本生物物理学会年会",,,,,,2022,Sept.
"Yancen Dai,Yuko Sato,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Kimura,Farid J. Ghadess,Hiroshi Ueda","Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting",,"Chemical Science","The Royal Society of Chemistry","Vol. 13","Issue 33","p. 9739-9748",2022,Aug.
"Junya Adachi,Toshiaki Fukushima,Haruka Oda,Hiroka Sugai,Kohei Sato,Hiroshi Kimura,Kazushi Kinbara","Development of Anthracene-Based Fluorescent Probes for Application in Cellular Systems","The 19th International Symposium on Novel Aromatic Compounds",,,,,,2022,July
"佐藤優子,内野哲志,岡翔平,木村宏","小分子抗体プローブを用いたエピジェネティクス修飾動態の生細胞イメージング","第78回 日本顕微鏡学会学術講演会",,,,,,2022,May
"Ani Grigoryan,Johannes Pospiech,Stephen Kr?mer,Daniel Lipka,Thomas Liehr,Hartmut Geiger,Hiroshi Kimura,Medhanie A Mulaw,Maria Carolina Florian","Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells",,"Stem Cell Reports",,"Vol. 16","No. 4","pp. 708-716",2022,Apr.
"Yancen Dai,Bo Zhu,Yuko Sato,Hiroshi Kimura,Farid J. Ghadessy,Tetsuya Kitaguchi,Hiroshi Ueda.","Development of an immunofluorescence probe Q-body for the direct visualization of tumor marker p53 in fixed and living cells.","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar.
"Rang FJ,de Luca KL,de Vries SS,Valdes-Quezada C,Boele E,Nguyen PD,Guerreiro I,Sato Y,Kimura H,Bakkers J,Kind J","Single-cell profiling of transcriptome and histone modifications with EpiDamID",,"Mol Cell",,,,,2022,Mar.
"Tadayoshi Murakawa,Tsuyoshi Nakamura,Kohei Kawaguchi,Futoshi Murayama,Ning Zhao,Timothy J. Stasevich,Hiroshi Kimura,Naonobu Fujita","A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body",,"Development",,"Vol. 149","No. 6",,2022,Mar.
"Tadayoshi Murakawa,Tsuyoshi Nakamura,Kohei Kawaguchi,Futoshi Murayama,Ning Zhao,Timothy J. Stasevich,Hiroshi Kimura,Naonobu Fujita","A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body",,"Development",,"Vol. 149","No. 6",,2022,Mar.
"Bartlett DA,Dileep V,Handa T,Ohkawa Y,Kimura H,Henikoff S","High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)",,"J Cell Biol",,"  220","  12","  e202103078",2022,Feb.
"Hiroshi Kimura,Yuko Sato","Imaging transcription elongation dynamics by new technologies unveils the organization of initiation and elongation in transcription factories",,"Current Opinion in Cell Biology",,"Volume 74",,"Page 71-79",2022,Feb.
"Yuko Sato,Satoshi Uchino,Hiroshi Kimura","Chromatin mobility of X-linked loci and its transcription regulation","The 30th Hot Spring Harbor International Symposium",,,,,,2022,Jan.
"Satoshi Uchino,Yuma Ito,Jessica Dai,Yuko Sato,Tetsuya Handa,Yasuyuki Ohkawa,Makio Tokunaga,Hiroshi Kimura","Live imaging of the initiation and elongation forms of RNA polymerase II using phosphorylation-specific probes.","The 30th Hot Spring Harbor International Symposium(Online)",,,,,,2022,Jan.
"Yohei Kono,Stephen A. Adam,Karen L. Reddy,Yixian Zheng,Ohad Medalia,Robert D. Goldman,Hiroshi Kimura,Takeshi Shimi","Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture with BAF and cGAS",,,,,,,2022,Jan.
"Esquivel-Chavez, Alfredo,Maki, Takahisa,Tsubouchi, Hideo,Handa, Testuya,Kimura, Hiroshi,Haber, James E.,Thon, Genevieve,Iwasaki, Hiroshi,Hiroshi Kimura","Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast <i>Schizosaccharomyces pombe</i>",,"Genes & Genetic Systems",,,,,2022,
"Kamiya, Naoki,Kuramoto, Kazuki,Takishima, Kento,Yumoto, Tatsuya,Oda, Haruka,Shimi, Takeshi,Kimura, Hiroshi,Matsushita, Michio,Fujiyoshi, Satoru,Hiroshi Kimura","Erratum: "Superfluid helium nanoscope insert with millimeter working range " [Vol 93, 103703 (2022)]",,"Review of Scientific Instruments",,,,,2022,
"Kamiya, Naoki,Kuramoto, Kazuki,Takishima, Kento,Yumoto, Tatsuya,Oda, Haruka,Shimi, Takeshi,Kimura, Hiroshi,Matsushita, Michio,Fujiyoshi, Satoru,Hiroshi Kimura","Superfluid helium nanoscope insert with millimeter working range",,"Review of Scientific Instruments",,,,,2022,
"Tomimatsu, Kosuke,Bihary, Dora,Olan, Ioana,Parry, Aled J.,Schoenfelder, Stefan,Chan, Adelyne S. L.,Slater, Guy St. C.,Ito, Yoko,Rugg-Gunn, Peter J.,Kirschner, Kristina,Bermejo-Rodriguez, Camino,Seko, Tomomi,Kugoh, Hiroyuki,Shiraishi, Ken,Sayama, Koji,Kimura, Hiroshi,Fraser, Peter,Narita, Masako,Samarajiwa, Shamith A.,Narita, Masashi,Hiroshi Kimura","Locus-specific induction of gene expression from heterochromatin loci during cellular senescence",,"Nature Aging",,,,,2022,
"Yancen Dai,Yuko Sato,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Kimura,Farid J. Ghadessy,Hiroshi Ueda","Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting",,"Chemical Science",,,,,2022,
"Kimura, H.,Sato, Y.,Hiroshi Kimura","Imaging transcription elongation dynamics by new technologies unveils the organization of initiation and elongation in transcription factories",,"Current Opinion in Cell Biology",,"Vol. 74",,"pp. 71-79",2022,
"Uchino, S.,Ito, Y.,Sato, Y.,Handa, T.,Ohkawa, Y.,Tokunaga, M.,Kimura, H.,Hiroshi Kimura","Live imaging of transcription sites using an elongating RNA polymerase II?specific probe",,"Journal of Cell Biology",,"Vol. 221","No. 2",,2022,
"Matsumura Y,Ito R,Yajima A,Yamaguchi R,Tanaka T,Kawamura T,Magoori K,Abe Y,Uchida A,Yoneshiro T,Hirakawa H,Zhang J,Arai M,Yang C,Yang G,Takahashi H,Fujihashi H,Nakaki R,Yamamoto S,Ota S,Tsutsumi S,Inoue SI,Hiroshi Kimura,Wada Y,Kodama T,Inagaki T,Osborne TF,Hiroyuki Aburatani,Node K,Sakai J","Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis",,"Nat Commun",,"  12","  1","  7045",2021,Dec.
"Hayashi-Takanaka Y,Hayashi Y,Hirano Y,Hiroshi Kimura","MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry",,"Nucleic Acids Research",,"  49","  21","  12152-12166",2021,Dec.
"Harada A,Kimura H,Ohkawa Y","Recent advances in single-cell epigenomics",,"Curr Opin Struct Biol",,"  71",,"  116-122",2021,Dec.
"内野 哲志,伊藤 由馬,佐藤 優子,半田 哲也,大川 恭行,徳永 万喜洋,木村 宏","リン酸化型RNAポリメラーゼII可視化プローブによる転写部位の生細胞観察","第39回染色体ワークショップ・第20回核ダイナミクス研究会, オンライン",,,,,,2021,Dec.
"内野 哲志,伊藤 由馬,Jessica Dai,佐藤 優子,半田 哲也,大川 恭行,徳永 万喜洋,木村 宏","転写伸長型RNAポリメラーゼII可視化プローブによる生細胞内における 転写伸長部位の観察","第44回日本分子生物学会年会",,,,,,2021,Dec.
"Uchino S,Ito Y,Sato Y,Handa T,Ohkawa Y,Tokunaga M,Kimura H","Live imaging of transcription sites using an elongating RNA polymerase II-specific probe.",,"J Cell Biol",,"Vol. 221","No. 2","p. e202104134 (23 pages)",2021,Dec.
"小澤弘樹,神戸梓沙,日比滉大,木村宏,白木伸明,粂 昭苑","メチオニン除去培養によるエピジェネティック変化を伴うヒトiPS細胞分化促進","第44回日本分子生物学会",,,,,,2021,Dec.
"Maehara K,Tomimatsu K,Harada A,Tanaka Kaori,Sato Shoko,Fukuoka M,Okada S,Handa T,Kurumizaka H,Saitoh N,Hiroshi Kimura,Ohkawa Y","Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections",,"Mol Syst Biol",,"  17","  11","  e10323",2021,Nov.
"佐藤優子,内野哲志,伊藤由馬,前原一満,大川恭行,徳永万喜洋,木村宏","生細胞プローブを用いた不活性化X染色体動態と転写制御の解析","第94回 日本生化学会大会",,,,,,2021,Nov.
"Yuko Sato,Masaru Nakao,Hiroshi Kimura","Live-cell imaging probes to track chromatin modification dynamics",,"Microscopy (Oxf)",,"Vol. 70","Issue 5","Page 415-422",2021,Oct.
"Hiroshi Kimura","Gene regulation and chromatin dynamics in living cells","The 79th of Annual Meeting of the Japanese Cancer Association",,,,,,2021,Oct.
"Kudo H,Matsuo M,Satoh S,Hata T,Hachisu R,Nakamura M,Yamamoto YY,Kimura H,Matsui M,Obokata J","Cryptic promoter activation occurs by at least two different mechanisms in the Arabidopsis genome",,"Plant J",,"  108","  1","  29-39",2021,Oct.
"Yang Liu,Ning Zhao,Masato T. Kanemaki,Yotaro Yamamoto,Yoshifusa Sadamura,Yuma Ito,Makio Tokunaga,Timothy J. Stasevich,Hiroshi Kimura","Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells",,"Genes Cells.",,"Vol. 26","No. 11","p. 905-926",2021,Sept.
"木村 宏","転写活性化に伴うヒストンアセチル化とクロマチンのダイナミクス","第93回 日本生化学会大会",,,,,,2021,Sept.
"Yuko Sato,Hiroshi Kimura","Multiplexed Imaging of Posttranslational Modifications of Endogenous Proteins in Live Cells",,"Methods in Molecular Biology",,"volume 2350",,"page 31-41",2021,July
"Zhang J,Matsumura Y,Kano Y,Yoshida A,Kawamura T,Hirakawa H,Inagaki T,Tanaka Toshiya,Hiroshi Kimura,Yanagi S,Fukami K,Doi T,Osborne TF,Kodama T,Aburatani H,Sakai J","Ubiquitination-dependent and -independent repression of target genes by SETDB1 reveal a context-dependent role for its methyltransferase activity during adipogenesis",,"Genes Cells",,"  26","  7","  513-529",2021,July
"Yuko Sato,Hiroshi Kimura","Dynamic Behavior of Inactive X Chromosome Territory During the Cell Cycle as Revealed by H3K27me3-Specific Intracellular Antibody",,"Methods in Molecular Biology",,"volume 1342",,,2021,June
"Tachiwana H,Dacher M,Maehara K,Harada A,Seto Y,Katayama R,Ohkawa Y,Kimura H,Kurumizaka H,Saitoh N","Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay.",,"eLife",,"  10",,"  e66290",2021,May
"Muraoka Y,Nikaido A,Kowada R,Kimura H,Yamaguchi M,Yoshida H","Identification of Rpd3 as a novel epigenetic regulator of Drosophila FIG 4, a Charcot-Marie-Tooth disease-causing gene",,"Neuroreport",,"  32","  7","  562-568",2021,May
"Mio K. Shibuta,Takuya Sakamoto,Tamako Yamaoka,Mayu Yoshikawa,Shusuke Kasamatsu,Noriyoshi Yagi,Satoru Fujimoto,Takamasa Suzuki,Satoshi Uchino,Yuko Sato,Hiroshi Kimura,Sachihiro Matsunaga","A live imaging system to analyze spatiotemporal dynamics of RNA polymerase II modification in Arabidopsis thaliana",,"Communications Biology",,"Volume 4",,,2021,May
"Forero-Quintero LS,Raymond W,Handa T,Saxton MN,Morisaki T,Kimura H,Bertrand E,Munsky B,Stasevich TJ","Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene",,"Nat Commun",,"  12","  1","  3158",2021,May
"Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Kimura,Hiroshi Ueda","Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies",,"ACS Omega","American Chemical Society","vol. 6","Issue 15","p. 10039-10046",2021,Apr.
"Uchino S,Ito Y,Sato Y,Handa T,Yasuyuki Ohkawa,Tokunaga M,Kimura H","Visualizing transcription sites in living cells using a genetically encoded probe specific for the elongating form of RNA polymerase II",,"bioRxiv",,,"No. 2021.04.27","p. 441582",2021,Apr.
"M. Hieda,T. Matsumoto,M. Isobe,S. Kurono,K. Yuka,S. Kametaka,J. Y. Wang,Y. H. Chi,K. Kameda,H. Kimura,N. Matsuura,S. Matsuura","The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal",,"Sci Rep",,"Vol. 11","No. 1","pp. 5358",2021,Mar.
"Hiroshi Kimura","Tracking histone and RNA polymerase II modifications in living cells using genetically encoded probes","RIKEN BDR Symposium",,,,,,2021,Mar.
"Lennart Hilbert,Yuko Sato,Ksenia Kuznetsova,Tommaso Bianucci,Hiroshi Kimura,Frank J?licher,Alf Honigmann,Vasily Zaburdaev,Nadine L. Vastenhouw","Transcription organizes euchromatin via microphase separation",,"Nature Communications",,"volume 12","No. 1","pp. 1360",2021,Mar.
"Sjoerd J D Tjalsma,Mayako Hori,Yuko Sato,Aurelie Bousard,Akito Ohi,Ana Cl?udia Raposo,Julia Roensch,Agnes Le Saux,Jumpei Nogami,Kazumitsu Maehara,Tomoya Kujirai,Tetsuya Handa,Sandra Bag?s-Arnal,Yasuyuki Ohkawa,Hitoshi Kurumizaka,Sim?o Teixeira da Rocha,Jan J ?ylicz,Hiroshi Kimura,Edith Heard","H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing",,"EMBO reports",,"volume 22","Issue 3","  e51989",2021,Mar.
"R. Sousa-Luﾃｭs,G. Dujardin,I. Zukher,H. Kimura,C. Weldon,M. Carmo-Fonseca,N. J. Proudfoot,T. Nojima","POINT technology illuminates the processing of polymerase-associated intact nascent transcripts",,"Mol Cell",,"Vol. 81","No. 9","pp. 1935-1950.e6",2021,Mar.
"Keita Ishida,Kanta Naruse,Yuta Mizouchi,Yoshihiro Ogawa,Michio Matsushita,Takeshi Shimi,Hiroshi Kimura,Satoru Fujiyoshi","Variable immersion microscopy with a high numerical aperture",,"Opt Lett",,"Vol. 46","No. 4","pp. 856-859",2021,Feb.
"C. H. Ho,Y. Takizawa,W. Kobayashi,Y. Arimura,H. Kimura,H. Kurumizaka","Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase",,"Life Sci Alliance",,"Vol. 4","No. 4",,2021,Feb.
"Yusuke Fujiwara,Yuki Yamanashi,Akiko Fujimura,Yuko Sato,Tomoya Kujirai,Hitoshi Kurumizaka,Hiroshi Kimura,Kenzo Yamatsugu,Shigehiro A. Kawashima,Motomu Kanai","Live-Cell Epigenome Manipulation by Synthetic Histone Acylation Catalyst System",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 118","No. 4",,2021,Jan.
"Hilbert, L.,Sato, Y.,Kuznetsova, K.,Bianucci, T.,Kimura, H.,J?licher, F.,Honigmann, A.,Zaburdaev, V.,Vastenhouw, N.L.,Hiroshi Kimura","Author Correction: Transcription organizes euchromatin via microphase separation (Nature Communications, (2021), 12, 1, (1360), 10.1038/s41467-021-21589-3)",,"Nature Communications",,"Vol. 12","No. 1",,2021,
"Ohhata, T.,Yamazawa, K.,Miura-Kamio, A.,Takahashi, S.,Sakai, S.,Tamura, Y.,Uchida, C.,Kitagawa, K.,Niida, H.,Hiratani, I.,Kobayashi, H.,Kimura, H.,Wutz, A.,Kitagawa, M.,Hiroshi Kimura","Dynamics of transcription-mediated conversion from euchromatin to facultative heterochromatin at the Xist promoter by Tsix",,"Cell Reports",,"Vol. 34","No. 13",,2021,
"Tada, M.,Hayashi, A.,Asano, Y.,Kubiura-Ichimaru, M.,Ito, T.,Yoshii, M.,Kimura, H.,Matsuda, Y.,Oshimura, M.,Hiroshi Kimura","Evidence for divergence of DNA methylation maintenance and a conserved inhibitory mechanism from DNA demethylation in chickens and mammals",,"Genes and Genomics",,"Vol. 43","No. 3","pp. 269-280",2021,
"Yuko Sato,Nguyen Thi Bich Ngoc,Haruka Oda,Tetsuya Handa,Hidenori Nishihara,Akihito Harada,Yasuyuki Ohkawa,Hiroshi Kimura","Spatiotemporal dynamics of histone modifications during zebrafish zygotic genome activation","第43回日本分子生物学会年会",,,,,,2020,Dec.
"佐藤優子,木村宏","生きた細胞でクロマチン修飾変化を見る Mintbody",,"実験医学別冊「クロマチン解析実践プロトコール」",,,,"pp. 233-240",2020,Dec.
"T. Imada,T. Shimi,A. Kaiho,Y. Saeki,H. Kimura","RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cells",,"Genes Cells",,"Vol. 26","No. 5","pp. 298-312",2020,Dec.
"Y. Sakamoto,M. Sato,Y. Sato,A. Harada,T. Suzuki,C. Goto,K. Tamura,K. Toyooka,H. Kimura,Y. Ohkawa,I. Hara-Nishimura,S. Takagi,S. Matsunaga","Subnuclear gene positioning through lamina association affects copper tolerance",,"Nat Commun",,"Vol. 11","No. 1","pp. 5914",2020,Nov.
"I. Olan,A. J. Parry,S. Schoenfelder,M. Narita,Y. Ito,A. S. L. Chan,G. S. C. Slater,D. Bihary,M. Bando,K. Shirahige,H. Kimura,S. A. Samarajiwa,P. Fraser","Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence",,"Nat Commun",,"Vol. 11","No. 1","pp. 6049",2020,Nov.
"佐藤優子,木村宏","Xist RNAの生細胞動態解析","第93回日本生化学会大会",,,,,,2020,Sept.
"D. T. Gruszka,S. Xie,H. Kimura,H. Yardimci","Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication",,"Sci Adv",,"Vol. 6","No. 38",,2020,Sept.
"Tetsuya Handa,Akihito Harada,Kazumitsu Maehara,Shoko Sato,Masaru Nakao,Naoki Goto,Hitoshi Kurumizaka,Yasuyuki Ohkawa,Hiroshi Kimura","Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input",,"Nat Protoc",,"Vol. 15","No. 10","pp. 3334-3360",2020,Aug.
"K. Otake,J. I. Ohzeki,N. Shono,K. Kugou,K. Okazaki,T. Nagase,H. Yamakawa,N. Kouprina,V. Larionov,H. Kimura,W. C. Earnshaw,H. Masumoto","CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly",,"J Cell Sci",,"Vol. 133","No. 15",,2020,July
"N. M. C. Martins,F. Cisneros-Soberanis,E. Pesenti,N. Y. Kochanova,W. H. Shang,T. Hori,T. Nagase,H. Kimura,V. Larionov,H. Masumoto,T. Fukagawa,W. C. Earnshaw","H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory",,"J Cell Sci",,"Vol. 133","No. 14",,2020,June
"S. Golfier,T. Quail,H. Kimura,J. Bruguﾃｩs","Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner",,"Elife",,"Vol. 9",,,2020,May
"N. A. Watson,T. N. Cartwright,C. Lawless,M. Cﾃ｡mara-Donoso,O. Sen,K. Sako,T. Hirota,H. Kimura,J. M. G. Higgins","Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites",,"Nat Commun",,"Vol. 11","No. 1","pp. 1684",2020,Apr.
"H. Ideno,K. Nakashima,K. Komatsu,R. Araki,M. Abe,Y. Arai,H. Kimura,Y. Shinkai,M. Tachibana,A. Nifuji","G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development",,"Bone",,"Vol. 137",,"pp. 115332",2020,Apr.
"Y. Higashijima,Y. Matsui,T. Shimamura,R. Nakaki,N. Nagai,S. Tsutsumi,Y. Abe,V. M. Link,M. Osaka,M. Yoshida,R. Watanabe,T. Tanaka,A. Taguchi,M. Miura,X. Ruan,G. Li,T. Inoue,M. Nangaku,H. Kimura,T. Furukawa,H. Aburatani,Y. Wada,Y. Ruan,C. K. Glass,Y. Kanki","Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells",,"Embo j",,"Vol. 39","No. 7","pp. e103949",2020,Apr.
"趙 寧,森崎達也,小田春佳,佐藤優子,木村 宏,Stasevich Timothy J","タンパク質1分子を翻訳過程からイメージング可能なプローブ「HA Frankenbody」",,"実験医学",,,"No. 38","pp. 613?617",2020,Feb.
"Y. Hayashi-Takanaka,Y. Kina,F. Nakamura,L. E. Becking,Y. Nakao,T. Nagase,N. Nozaki,H. Kimura","Histone modification dynamics as revealed by multicolor immunofluorescence-based single-cell analysis",,"J Cell Sci",,"Vol. 133","No. 14",,2020,Jan.
"木村宏,半田哲也","ヒストン修飾解析の最前線",,"遺伝子医学",,,"No. 10","pp. 124?129",2020,Jan.
"Ochiai, H.,Hayashi, T.,Umeda, M.,Yoshimura, M.,Harada, A.,Shimizu, Y.,Nakano, K.,Saitoh, N.,Liu, Z.,Yamamoto, T.,Okamura, T.,Ohkawa, Y.,Kimura, H.,Nikaido, I.,Hiroshi Kimura","Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells",,"Science Advances",,"Vol. 6","No. 25",,2020,
"木村 宏","ゼブラフィッシュ胚性ゲノム活性化におけるヒストンアセチル化の役割と核内環境変化","第42回日本分子生物学会年会",,,,,,2019,Dec.
"R. Nakato,Y. Wada,R. Nakaki,G. Nagae,Y. Katou,S. Tsutsumi,N. Nakajima,H. Fukuhara,A. Iguchi,T. Kohro,Y. Kanki,Y. Saito,M. Kobayashi,A. Izumi-Taguchi,N. Osato,K. Tatsuno,A. Kamio,Y. Hayashi-Takanaka,H. Wada,S. Ohta,M. Aikawa,H. Nakajima,M. Nakamura,R. C. McGee,K. W. Heppner,T. Kawakatsu,M. Genno,H. Yanase,H. Kume,T. Senbonmatsu,Y. Homma,S. Nishimura,T. Mitsuyama,H. Aburatani,H. Kimura,K. Shirahige","Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells",,"Epigenetics Chromatin",,"Vol. 12","No. 1","pp. 77",2019,Dec.
"Hiroshi Kimura","Roles of histone acetylation and nuclear F-actin in zebrafish embryo development","Chromosome Dynamics - An international symposium on chromatin and chromosome stability.",,,,,,2019,Dec.
"M. Dacher,H. Tachiwana,N. Horikoshi,T. Kujirai,H. Taguchi,H. Kimura,H. Kurumizaka","Incorporation and influence of Leishmania histone H3 in chromatin",,"Nucleic Acids Res",,"Vol. 47","No. 22","pp. 11637-11648",2019,Nov.
"S. Nakamura,S. Hira,M. Fujiwara,N. Miyagata,T. Tsuji,A. Kondo,H. Kimura,Y. Shinozuka,M. Hayashi,S. Kobayashi,M. Mukai","A truncated form of a transcription factor Mamo activates vasa in Drosophila embryos",,"Commun Biol",,"Vol. 2",,"pp. 422",2019,Nov.
"Hiroshi Kimura","Single-cell histone modification analysis: from live-cell imaging to epigenome profiling.","Single Cell Omics Germany Workshop "Advances in single cell epigenomics 2019"",,,,,,2019,Nov.
"K. Suda,Y. Muraoka,A. Ortega-Yanez,H. Yoshida,F. Kizu,T. Hochin,H. Kimura,M. Yamaguchi","Reduction of Rpd3 suppresses defects in locomotive ability and neuronal morphology induced by the knockdown of Drosophila SLC25A46 via an epigenetic pathway",,"Exp Cell Res",,"Vol. 385","No. 2","pp. 111673",2019,Oct.
"木村宏","ヘテロクロマチンのダイナミクス","平成31年度遺伝研研究会「クロマチン・細胞核の形成とダイナミクスによるゲノム制御」",,,,,,2019,Oct.
"F. Ohka,K. Shinjo,S. Deguchi,Y. Matsui,Y. Okuno,K. Katsushima,M. Suzuki,A. Kato,N. Ogiso,A. Yamamichi,K. Aoki,H. Suzuki,S. Sato,N. Arul Rayan,S. Prabhakar,J. Goke,T. Shimamura,R. Maruyama,S. Takahashi,A. Suzumura,H. Kimura,T. Wakabayashi,H. Zong,A. Natsume,Y. Kondo","Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas",,"Cancer Res",,"Vol. 79","No. 19","pp. 4814-4827",2019,Oct.
"A. Karoutas,W. Szymanski,T. Rausch,S. Guhathakurta,E. A. Rog-Zielinska,R. Peyronnet,J. Seyfferth,H. R. Chen,R. de Leeuw,B. Herquel,H. Kimura,G. Mittler,P. Kohl,O. Medalia,J. O. Korbel,A. Akhtar","The NSL complex maintains nuclear architecture stability via lamin A/C acetylation",,"Nat Cell Biol",,"Vol. 21","No. 10","pp. 1248-1260",2019,Oct.
"Hiroshi Kimura","Tracking RNA polymerase II and histone modification dynamics during the zygotic genome activation","第92回日本生化学会大会",,,,,,2019,Oct.
"Yuko Sato,Lennart Hilbert,Haruka Oda,Yinan Wan,John M. Heddleston,Teng-Leong Chew,Vasily Zaburdaev,Philipp Keller,Timothee Lionnet,Nadine Vastenhouw,Hiroshi Kimura","Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live cell analysis",,"Development",,"vol. 146","no. 19",,2019,Sept.
"Chenjiang Liu,Yoshihiro Kobashigawa,Soichiro Yamauchi,Yuya Toyota,Manaka Teramoto,Yuka Ikeguchi,Natsuki Fukuda,Takashi Sato,Yuko Sato,Hiroshi Kimura,Hiroshi Morioka","Preparation of single-chain Fv antibodies in the cytoplasm of Escherichia coli by simplified and systematic chaperone optimization",,"The Journal of Biochemistry,",,"Volume 166","Issue 6","Page 455-462",2019,Sept.
"大室有紀,北口哲也,木村宏,上田宏","YFP断片融合抗体プローブを用いたヒストン翻訳後修飾検出系の構築","第 71回日本生物工学会大会","第 71回日本生物工学会大会要旨集",,,,,2019,Sept.
"Hiroshi Kimura","Modification-specific intracellular antibodies for monitoring histone modification in vivo","3rd Epigenetics and Bioengineering Conference (EpiBio 2019)",,,,,,2019,Sept.
"Hiroshi Kimura","Chromatin modification dynamics during the activation and inactivation of transcription","Gordon Research Conference "Genome Architecture in Cell Fate and Disease"",,,,,,2019,Aug.
"N. Horikoshi,T. Kujirai,K. Sato,H. Kimura,H. Kurumizaka","Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo",,"Biochem Biophys Res Commun",,"Vol. 515","No. 4","pp. 719-724",2019,Aug.
"S. Yamauchi,Y. Kobashigawa,N. Fukuda,M. Teramoto,Y. Toyota,C. Liu,Y. Ikeguchi,T. Sato,Y. Sato,H. Kimura,T. Masuda,S. Ohtsuki,K. Noi,T. Ogura,H. Morioka","Cyclization of Single-Chain Fv Antibodies Markedly Suppressed Their Characteristic Aggregation Mediated by Inter-Chain VH-VL Interactions",,"Molecules",,"Vol. 24","No. 14",,2019,July
"N. Zhao,K. Kamijo,P. D. Fox,H. Oda,T. Morisaki,Y. Sato,H. Kimura,T. J. Stasevich","A genetically encoded probe for imaging nascent and mature HA-tagged proteins in vivo",,"Nat Commun",,"Vol. 10","No. 1","pp. 2947",2019,July
"A. Murashima,K. Shinjo,K. Katsushima,T. Onuki,Y. Kondoh,H. Osada,N. Kagaya,K. Shin-Ya,H. Kimura,M. Yoshida,S. Murakami,Y. Kondo","Identification of a chemical modulator of EZH2-mediated silencing by cell-based high-throughput screening assay",,"J Biochem",,"Vol. 166","No. 1","pp. 41-50",2019,July
"Chan-I Chung,Yuko Sato,Yuki Ohmuro-Matsuyama,Shinichi Machida,Hitoshi Kurumizaka,Hiroshi Kimura,Hiroshi Ueda","Intrabody-based FRET probe to visualize endogenous histone acetylation",,"Scientific Reports","Springer-Nature","Vol. 9","No. 1","pp. 10188",2019,July
"Yuko Sato,Lennart Hilbert,Vasily Zaburdaev,Nadine Vastenhouw,Hiroshi Kimura","Histone modification dynamics during zygotic genome activation","International Symposium for Female Researchers in Chromatin Biology 2019",,,,,,2019,June
"大室有紀,北口哲也,木村宏,上田宏","分割YFP融合Intrabodyを用いた生細胞内ヒストンアセチル化検出プローブの構築","第19回日本蛋白質科学会年会","第19回日本蛋白質科学会年会要旨集",,,,,2019,June
"Y. Hayashi-Takanaka,Y. Kina,F. Nakamura,S. Yamazaki,M. Harata,Rwmv Soest,H. Kimura,Y. Nakao","Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells",,"Sci Rep",,"Vol. 9","No. 1","pp. 7540",2019,May
"Ryosuke Nagashima,Kayo Hibino,S.S. Ashwin,Michael Babokhov,Shin Fujishiro,Ryosuke Imai,Tadasu Nozaki,Sachiko Tamura,Tomomi Tani,Hiroshi Kimura,Michael Shribak,Masato T. Kanemaki,Masaki Sasai,Kazuhiro Maeshima","Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II",,"Journal of Cell Biology",,"Vol. 218","No. 5","pp. 1511?1530",2019,Mar.
"K. Yamagata,K. Nagai,H. Miyamoto,M. Anzai,H. Kato,K. Miyamoto,S. Kurosaka,R. Azuma,II Kolodeznikov,A. V. Protopopov,V. V. Plotnikov,H. Kobayashi,R. Kawahara-Miki,T. Kono,M. Uchida,Y. Shibata,T. Handa,Y. Hosoi,T. Mitani,K. Matsumoto,A. Iritani,K. Yamagata,K. Nagai,H. Miyamoto,M. Anzai,H. Kato,K. Miyamoto,S. Kurosaka,R. Azuma,II Kolodeznikov,A. V. Protopopov,V. V. Plotnikov,H. Kobayashi,R. Kawahara-Miki,T. Kono,M. Uchida,Y. Shibata,T. Handa,H. Kimura,Y. Hosoi,T. Mitani,K. Matsumoto,A. Iritani","Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging",,"Sci Rep",,"Vol. 9","No. 1","pp. 4050",2019,Mar.
"Y. Arimura,H. Tachiwana,H. Takagi,T. Hori,H. Kimura,T. Fukagawa,H. Kurumizaka","The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism",,"Nat Commun",,"Vol. 10","No. 1","pp. 576",2019,Feb.
"T. Matsuda,T. Irie,S. Katsurabayashi,Y. Hayashi,T. Nagai,N. Hamazaki,A. M. D. Adefuin,F. Miura,T. Ito,H. Kimura,K. Shirahige,T. Takeda,K. Iwasaki,T. Imamura,K. Nakashima","Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion",,"Neuron",,"Vol. 101","No. 3","pp. 472-485.e7",2019,Feb.
"A. K. Okita,F. Zafar,J. Su,D. Weerasekara,T. Kajitani,T. S. Takahashi,H. Kimura,Y. Murakami,H. Masukata,T. Nakagawa","Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription",,"Commun Biol",,"Vol. 2","no. 17","pp. 17",2019,Jan.
"Takeshi Shimi,Hiroshi Kimura","A mosaic of old and young nucleoporins.",,"J Cell Biol",,"Vol. 218","No. 2","pp. 385?386",2019,Jan.
"木村宏","FRAP/FLIP―フォトブリーチによる生細胞内分子動態計測",,"実験医学",,"Vol. 36","no. 20","pp. 3398?3399",2018,Dec.
"木村宏","ヒストン修飾と特異的モノクローナル抗体",,"Dojin News",,,"No. 166","pp. 1?5",2018,Dec.
"Tetsuya Handa,Hiroshi Kimura","A chromatin integration labelling method enables epigenomic profiling with lower input",,"Nat Cell Biol",,"Vol. 21","No. 2","pp. 287?296",2018,Dec.
"木村宏","ヒストンの細胞内ダイナミクス",,"実験医学",,"Vol. 36","no. 17","pp. 2890?2896",2018,Nov.
"Y. Arimura,M. Ikura,R. Fujita,M. Noda,W. Kobayashi,N. Horikoshi,J. Sun,L. Shi,M. Kusakabe,M. Harata,Y. Ohkawa,S. Tashiro,H. Kimura,T. Ikura,H. Kurumizaka","Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome",,"Nucleic Acids Res",,"Vol. 46","No. 19","pp. 10007-10018",2018,Nov.
"Yuko Sato,Timothy J. Stasevich,Hiroshi Kimura","Visualizing the Dynamics of Inactive X Chromosomes in Living Cells Using Antibody-Based Fluorescent Probes",,"Methods Mol Biol","Humana, New York, NY","Vol. 1861",,"pp. 91-102",2018,Sept.
"Shuntaro Sato,Yuma Ito,Yuko Sato,Hiroshi Kimura,Makio Tokunaga","Single-molecule imaging of post-translational modification using genetically encoded antibody probe.","The 56th Annual Meeting of the Biophysical Society of Japan",,,,,,2018,Sept.
"Y. Azuma,H. Imai,Y. Kawaguchi,I. Nakase,H. Kimura,S. Futaki","Modular Redesign of a Cationic Lytic Peptide To Promote the Endosomal Escape of Biomacromolecules",,"Angew Chem Int Ed Engl",,"Vol. 57","No. 39","pp. 12771-12774",2018,Sept.
"L. Handoko,B. Kaczkowski,C. C. Hon,M. Lizio,M. Wakamori,T. Matsuda,T. Ito,P. Jeyamohan,Y. Sato,K. Sakamoto,S. Yokoyama,H. Kimura,A. Minoda,T. Umehara","JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states",,"Epigenetics",,"Vol. 13","No. 4","pp. 410-431",2018,Aug.
"Lusy Handoko,Bogumil Kaczkowski,Chung-Chau Hon,Marina Lizio,Masatoshi Wakamori,Takayoshi Matsuda,Takuhiro Ito,Prashanti Jeyamohan,Yuko Sato,Kensaku Sakamoto,Shigeyuki Yokoyama,Hiroshi Kimura,Aki Minoda,Takashi Umehara","JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states",,"Epigenetics",,"Volume 13","Issue 4","Page 410-431",2018,Aug.
"佐藤優子,木村宏","遺伝子不活性化マークを生細胞で観察できる蛍光プローブ",,"化學工業",,"Vol. 69","No. 8","pp. 589?594",2018,Aug.
"M. R. Higgs,K. Sato,J. J. Reynolds,S. Begum,R. Bayley,A. Goula,A. Vernet,K. L. Paquin,D. G. Skalnik,W. Kobayashi,M. Takata,N. G. Howlett,H. Kurumizaka,H. Kimura,G. S. Stewart","Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2",,"Mol Cell",,"Vol. 71","No. 1","pp. 25-41.e6",2018,July
"E. Arai,F. Miura,Y. Totoki,S. Yamashita,Y. Tian,M. Gotoh,H. Ojima,H. Nakagawa,Y. Takahashi,H. Nakamura,N. Hama,M. Kato,H. Kimura,Y. Suzuki,T. Ito,T. Shibata,Y. Kanai","Epigenome mapping of human normal purified hepatocytes: personal epigenome variation and genome-epigenome correlation",,"Epigenomics",,"Vol. 10","No. 7","pp. 955-979",2018,July
"A. Takeuchi,K. Iida,T. Tsubota,M. Hosokawa,M. Denawa,J. B. Brown,K. Ninomiya,M. Ito,H. Kimura,T. Abe,H. Kiyonari,K. Ohno,M. Hagiwara","Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain",,"Cell Rep",,"Vol. 23","No. 5","pp. 1326-1341",2018,May
"A. J. Parry,M. Hoare,D. Bihary,R. Hansel-Hertsch,S. Smith,K. Tomimatsu,E. Mannion,A. Smith,P. D'Santos,I. A. Russell,S. Balasubramanian,H. Kimura,S. A. Samarajiwa,M. Narita","NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence",,"Nat Commun",,"Vol. 9","No. 1","pp. 1840",2018,May
"Yuko Sato,Hiroshi Kimura","Zygotic genome activation is dynamically mediated by histone acetylation in zebrafish","Cold Spring Harbor Laboratory Meeting “Nuclear Organization & Function”",,,,,,2018,May
"佐藤優子,木村宏","細胞内抗体Mintbodyを用いた生細胞エピジェネティクス解析","日本エピジェネティクス研究会年会",,,,,,2018,May
"S. Kuroki,Y. Nakai,R. Maeda,N. Okashita,M. Akiyoshi,Y. Yamaguchi,S. Kitano,H. Miyachi,R. Nakato,K. Ichiyanagi,K. Shirahige,H. Kimura,Y. Shinkai,M. Tachibana","Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis",,"Stem Cell Reports",,"Vol. 10","No. 4","pp. 1340-1354",2018,Apr.
"木村宏","ヌクレオームコンソーシアム",,"生物物理",,"Vol. 58","No. 4","pp. 221?222",2018,Apr.
"Akihito Harada,Kazumitsu Maehara,Yusuke Ono,Hiroyuki Taguchi,Kiyoshi Yoshioka,Yasuo Kitajima,Yan Xie,Yuko Sato,Takeshi Iwasaki,Jumpei Nogami,Seiji Okada,Tetsuro Komatsu,Yuichiro Semba,Tatsuya Takemoto,Hiroshi Kimura,Hitoshi Kurumizaka,Yasuyuki Ohkawa","Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration",,"Nature Communications",,"vol. 9",,,2018,Apr.
"Y. Abe,Y. Fujiwara,H. Takahashi,Y. Matsumura,T. Sawada,S. Jiang,R. Nakaki,A. Uchida,N. Nagao,M. Naito,S. Kajimura,H. Kimura,T. F. Osborne,H. Aburatani,T. Kodama,T. Inagaki,J. Sakai","Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch",,"Nat Commun",,"Vol. 9","No. 1","pp. 1566",2018,Apr.
"J. G. Ruppert,K. Samejima,M. Platani,O. Molina,H. Kimura,A. A. Jeyaprakash,S. Ohta,W. C. Earnshaw","HP1alpha targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry",,"Embo j",,"Vol. 37","No. 6",,2018,Mar.
"木村宏","生細胞イメージングによりとらえるクロマチンの修飾および遺伝子発現の活性化",,"領域融合レビュー",,,,,2018,Feb.
"C. C. L. Chen,P. Goyal,M. M. Karimi,M. H. Abildgaard,H. Kimura,M. C. Lorincz","H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2",,"Genome Res",,"Vol. 28","No. 1","pp. 37-51",2018,Jan.
"C. Jenness,S. Giunta,M. M. Muller,H. Kimura,T. W. Muir,H. Funabiki","HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome",,"Proceedings of the National Academy of Sciences of the United States of America",,,,,2018,Jan.
"K. Shiraishi,A. Shindo,A. Harada,H. Kurumizaka,H. Kimura,Y. Ohkawa,H. Matsuyama","Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders",,"Andrology",,"Vol. 6","No. 1","pp. 158-165",2018,
"T. Kajitani,H. Kato,Y. Chikashige,C. Tsutsumi,Y. Hiraoka,H. Kimura,Y. Ohkawa,C. Obuse,D. Hermand,Y. Murakami","Ser7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAi",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 114","No. 52","pp. E11208-e11217",2017,Dec.
"Ideno, Hisashi,Kamiunten, Taichi,Shimada, Akemi,Terashima, Tatsuo,Nakashima, Kazuhisa,Tomooka, Yasuhiro,Nakamura, Yoshiki,Hiroshi Kimura,Tachibana, Makoto,Nifuji, Akira","H3K9MTase G9a regulates tooth development in mice.","Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR)","JOURNAL OF BONE AND MINERAL RESEARCH","WILEY","Vol. 32",,"pp. S334-S334",2017,Dec.
"木村宏,佐藤優子","遺伝子発現の理解と制御のための「ヌクレオーム」研究とエピゲノム編集",,"JATAFFジャーナル",,"Vol. 7","No. 5","pp. 3?6",2017,Nov.
"L. Imre,Z. Simandi,A. Horvath,G. Fenyofalvi,P. Nanasi,E. F. Niaki,E. Hegedus,Z. Bacso,U. Weyemi,R. Mauser,J. Ausio,A. Jeltsch,W. Bonner,L. Nagy,H. Kimura,G. Szabo","Nucleosome stability measured in situ by automated quantitative imaging",,"Scientific reports",,"Vol. 7","No. 1","pp. 12734",2017,Oct.
"Nanasi, P.,Imre, L.,Horvath, A.,Halasz, L.,Szanto, A.,Hiroshi Kimura,Szekvolgyi, L.,Nagy, L.,Szabo, G.","Breaking good:+1 nucleosome destabilization by nicking","42nd Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back","FEBS JOURNAL","WILEY","Vol. 284",,"pp. 221-221",2017,Sept.
"T. Kamiunten,H. Ideno,A. Shimada,Y. Arai,T. Terashima,Y. Tomooka,Y. Nakamura,K. Nakashima,H. Kimura,Y. Shinkai,M. Tachibana,A. Nifuji","Essential roles of G9a in cell proliferation and differentiation during tooth development",,"Experimental cell research",,"Vol. 357","No. 2","pp. 202-210",2017,Aug.
"A. Shirai,T. Kawaguchi,H. Shimojo,D. Muramatsu,M. Ishida-Yonetani,Y. Nishimura,H. Kimura,J. I. Nakayama,Y. Shinkai","Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly",,"eLife",,"Vol. 6",,,2017,Aug.
"P. N. T. An,K. Shimaji,R. Tanaka,H. Yoshida,H. Kimura,E. Fukusaki,M. Yamaguchi","Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a",,"Scientific reports",,"Vol. 7","No. 1","pp. 7343",2017,Aug.
"S. Y. Isobe,K. Nagao,N. Nozaki,H. Kimura,C. Obuse","Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair",,"Cell reports",,"Vol. 20","No. 2","pp. 297-307",2017,July
"R. Arai,T. Sugawara,Y. Minakuchi,Yuko Sato,A. Toyoda,K. Nabeshima,H. Kimura,A. Kimura","Reduction in chromosome mobility accompanies nuclear organization during early embryogenesis in Caenorhabditis elegans",,"Scientific reports",,"Vol. 7","No. 1","pp. 3631",2017,June
"Yuko Sato,Hiroshi Kimura","Semi-quantitative Analysis of H4K20me1 Levels in Living Cells Using Mintbody",,"bio-protocol",,"vol. 7","no. 10",,2017,May
"T. Yamazaki,Y. Hatano,T. Handa,S. Kato,K. Hoida,R. Yamamura,T. Fukuyama,T. Uematsu,N. Kobayashi,H. Kimura,K. Yamagata","Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase",,"PloS one",,"Vol. 12","No. 5","pp. e0177764",2017,May
"K. Kurita,T. Sakamoto,N. Yagi,Y. Sakamoto,A. Ito,N. Nishino,K. Sako,M. Yoshida,H. Kimura,M. Seki,S. Matsunaga","Live imaging of H3K9 acetylation in plant cells",,"Scientific reports",,"Vol. 7",,"pp. 45894",2017,Apr.
"H. Taguchi,Y. Xie,N. Horikoshi,K. Maehara,A. Harada,J. Nogami,K. Sato,Y. Arimura,A. Osakabe,T. Kujirai,T. Iwasaki,Y. Semba,T. Tachibana,H. Kimura,Y. Ohkawa,H. Kurumizaka","Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8",,"Biochemistry",,"Vol. 56","No. 16","pp. 2184-2196",2017,Apr.
"M. Partolina,H. C. Thoms,K. G. MacLeod,G. Rodriguez-Blanco,M. N. Clarke,A. V. Venkatasubramani,R. Beesoo,V. Larionov,V. S. Neergheen-Bhujun,B. Serrels,H. Kimura,N. O. Carragher,A. Kagansky","Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array",,"Cell death discovery",,"Vol. 3",,"pp. 16077",2017,Mar.
"Hilbert, Lennart,Yuko Sato,Hiroshi Kimura,Honigmann, Alf,Zaburdaev, Vasily,Vastenhouw, Nadine","Transcription Locally Disperses Chromatin and Thereby Organizes the Global Architecture of Interphase Nuclei","58th Annual Meeting of the Biophysical-Society","BIOPHYSICAL JOURNAL","CELL PRESS","Vol. 112","No. 3","pp. 211A-211A",2017,Feb.
"Ideno, H.,Komatsu, K.,Shimada, A.,Arai, Y.,Nakashima, K.,Tachibana, M.,Hiroshi Kimura,Nifuji, A.","Histone methyltransferase G9a is essential for osteoblastic differentiation and skull bone formation during development.","ASCB/EMBO Meeting","MOLECULAR BIOLOGY OF THE CELL","AMER SOC CELL BIOLOGY","Vol. 28",,,2017,
"Hilbert, L.,Sato, Y.,Hiroshi Kimura,Julicher, F.,Honigmann, A.,Zaburdaev, V.,Vastenhouw, N.","Interphase chromatin is adaptively folded by ongoing transcription and RNA accumulation.","ASCB/EMBO Meeting","MOLECULAR BIOLOGY OF THE CELL","AMER SOC CELL BIOLOGY","Vol. 28",,,2017,
"木村宏","エピゲノム解析手法の標準化；ヒストン修飾解析",,"実験医学増刊：『エピゲノム研究：修飾の全体像の理解から先制・個別化医療へ』","羊土社",,,"p. 32?37",2017,
"田代聡,木村宏","Nucleome研究の世界動向",,"実験医学","羊土社","Vol. 35",,"p. 78?82",2017,
"E. Kakumu,S. Nakanishi,H. M. Shiratori,A. Kato,W. Kobayashi,S. Machida,T. Yasuda,N. Adachi,N. Saito,T. Ikura,H. Kurumizaka,H. Kimura,M. Yokoi,W. Sakai,K. Sugasawa","Xeroderma pigmentosum group C protein interacts with histones: regulation by acetylated states of histone H3",,"Genes to cells : devoted to molecular & cellular mechanisms",,,,,2017,
"Y. Shishido,T. Baba,T. Sato,Y. Shima,K. Miyabayashi,M. Inoue,H. Akiyama,H. Kimura,Y. Kanai,Y. Ishihara,S. Haraguchi,A. Miyazaki,D. Rozman,T. Yamazaki,M. H. Choi,Y. Ohkawa,M. Suyama,K. I. Morohashi","Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells",,"Scientific reports",,"Vol. 7",,"pp. 41912",2017,
"J. Ueda,A. Harada,T. Urahama,S. Machida,K. Maehara,M. Hada,Y. Makino,J. Nogami,N. Horikoshi,A. Osakabe,H. Taguchi,H. Tanaka,H. Tachiwana,T. Yao,M. Yamada,T. Iwamoto,A. Isotani,M. Ikawa,T. Tachibana,Y. Okada,H. Kimura,Y. Ohkawa,H. Kurumizaka,K. Yamagata","Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis",,"Cell reports",,"Vol. 18","No. 3","pp. 593-600",2017,
"木村宏,佐藤優子","ゲノム，エピゲノムからヌクレオームへ：遺伝情報発現制御機構の包括的理解に向けて",,"情報管理","国立研究開発法人 科学技術振興機構","Vol. 60","No. 8","pp. 555-563",2017,
"T. Shiomi,A. Muto,S. Hozumi,H. Kimura,Y. Kikuchi","Histone H3 Lysine 27 Trimethylation Leads to Loss of Mesendodermal Competence During Gastrulation in Zebrafish Ectodermal Cells",,"Zoological science",,"Vol. 34","No. 1","pp. 64-71",2017,
"Kajitani, Takuya,Kato, Hiroaki,Chikashige, Yuji,Hiroshi Kimura,Ohkawa, Yasuyuki,Herand, Damien,Murakami, Yota","Phosphorylation at Ser7 of RNA polymerase II CTD limits transcription speed and transcription elongation",,"GENES & GENETIC SYSTEMS","GENETICS SOC JAPAN","Vol. 91","No. 6","pp. 348-348",2016,Dec.
"神戸梓沙,白木伸明,木村宏,粂昭苑","ヒトiPS細胞におけるメチオニン代謝とヒストン修飾の役割","第39回日本分子生物学会年会",,,,,,2016,Dec.
"伊藤由馬,原田昌彦,木村宏,十川久美子,徳永万喜洋","１分子イメージングとFRAPによるINO80クロマチン再構成複合体の核内動態解析","第8回「光塾」",,,,,,2016,Dec.
"Nagao, Koji,Isobe, Shin-Ya,Ohkubo, Yoshi-Nobu,Hayashi-Takanaka, Yoko,Hiroshi Kimura,Sado, Takashi,Obuse, Chikashi","Constitution of Higher Order Heterochromatin Structure Based on Epigenetic Code",,"GENES & GENETIC SYSTEMS","GENETICS SOC JAPAN","Vol. 91","No. 6","pp. 318-318",2016,Dec.
"Tsubasa Isogaki,Yuma Ito,Shota Ichikawa,Hiroshi Kimura,Masahiko Harata,Kumiko Sakata-Sogawa,Makio Tokunaga","Fluorescence recovery after photobleaching(FRAP) analysis of INO80 chromatin remodeling complex","The 54th Annual Meeting of the Biophysical Society of Japan",,,,,,2016,Nov.
"Yuki Kuniyoshi,Kazumitsu Maehara,Takeshi Iwasaki,Masayasu Hayashi,Yuichiro Semba,Masatoshi Fujita,Yuko Sato,Hiroshi Kimura,Akihito Harada,Yasuyuki Ohkawa","Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas",,"PLOS ONE",,"vol. 11","no. 10",,2016,Oct.
"Y. Sato,T. Kujirai,R. Arai,H. Asakawa,C. Ohtsuki,N. Horikoshi,K. Yamagata,J. Ueda,T. Nagase,T. Haraguchi,Y. Hiraoka,A. Kimura,H. Kurumizaka,H. Kimura","A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation",,"J Mol Biol",,"Vol. 428","No. 20","pp. 3885-3902",2016,Oct.
"R. Hansel-Hertsch,D. Beraldi,S. V. Lensing,G. Marsico,K. Zyner,A. Parry,M. Di Antonio,J. Pike,H. Kimura,M. Narita,D. Tannahill,S. Balasubramanian","G-quadruplex structures mark human regulatory chromatin",,"Nature genetics",,,,,2016,
"Y. Kang,J. Wang,A. Neff,S. Kratzer,H. Kimura,R. E. Davis","Differential Chromosomal Localization of Centromeric Histone CENP-A Contributes to Nematode Programmed DNA Elimination",,"Cell reports",,,,,2016,
"T. Kujirai,N. Horikoshi,K. Sato,K. Maehara,S. Machida,A. Osakabe,H. Kimura,Y. Ohkawa,H. Kurumizaka","Structure and function of human histone H3.Y nucleosome",,"Nucleic acids research",,"Vol. 44","No. 13","pp. 6127-41",2016,
"J. Ohzeki,N. Shono,K. Otake,N. M. Martins,K. Kugou,H. Kimura,T. Nagase,V. Larionov,W. C. Earnshaw,H. Masumoto","KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation",,"Developmental cell",,"Vol. 37","No. 5","pp. 413-27",2016,
"K. Shimaji,T. Konishi,H. Yoshida,H. Kimura,M. Yamaguchi","Genome-wide genetic screen identified the link between dG9a and epidermal growth factor receptor signaling pathway in vivo",,"Experimental cell research",,"Vol. 346","No. 1","pp. 53-64",2016,
"M. Suzuki,C. Takagi,S. Miura,Y. Sakane,T. Sakuma,N. Sakamoto,T. Endo,Y. Kamei,Y. Sato,H. Kimura,T. Yamamoto,N. Ueno,K. T. Suzuki","In vivo tracking of histone H3 lysine 9 acetylation in Xenopus laevis during tail regeneration",,"Genes Cells",,"Vol. 21","No. 4","pp. 358-69",2016,
"S. Suzuki,H. Kato,Y. Suzuki,Y. Chikashige,Y. Hiraoka,H. Kimura,K. Nagao,C. Obuse,S. Takahata,Y. Murakami","Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast",,"Nucleic acids research",,"Vol. 44","No. 9","pp. 4147-62",2016,
"S. Koide,M. Oshima,K. Takubo,S. Yamazaki,E. Nitta,A. Saraya,K. Aoyama,Y. Kato,S. Miyagi,Y. Nakajima-Takagi,T. Chiba,H. Matsui,F. Arai,Y. Suzuki,H. Kimura,H. Nakauchi,T. Suda,Y. Shinkai,A. Iwama","Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes",,"Blood",,"Vol. 128","No. 5","pp. 638-49",2016,
"縣 保年,我妻 慶祐,寺田 晃士,田中 裕之,伊川 友活,増田 喬子,河本 宏,木村 宏","E2A転写因子 foci を足場としたT細胞受容体遺伝子座の染色体ダイナミクス","第10回エピジェネティクス研究会年会",,,,,,2016,
"白井 温子,川口 隆之,村松 大輔,石田 真由美,木村 宏,中山 潤一,眞貝 洋一","ヒストンメチル化酵素Suv39h1を介したヘテロクロマチン形成機構の解明","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"桝本 寛,庄野 暢晃,大関 潤一郎,大竹 興一郎,長瀬 隆弘,木村 宏,Larionov Vladimir,Earnshaw William C","合成セントロメアDNAとtetO/tetRデザリングシステムを用いたセントロメアクロマチン集合機構の解明・キネトコア機能とセントロメアエピヘネティクスの繋がり","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"大関 淳一郎,庄野 暢晃,大竹 興一郎,久郷 和人,木村 宏,長瀬 隆弘,LarionovVladimir,William Earnshaw,桝本 寛","アセチル化酵素KAT７によるヒストン交換反応はヘテロクロマチン化に拮抗してCENP-A集合を促進する",,,,,,,2016,
"梶谷 卓也,加藤 太陽,近重 裕次,平岡 泰,鈴木 穣,木村 宏,大川 恭行,小布施 力史,Hermand damien,村上 洋太","RNAP?-CTD Ser7のﾘﾝ酸化は転写を減速させることでncRNAのクロマチン結合を促進しヘテロクロマチン形成を行う","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"木村 宏,林 陽子,大川 恭行,野崎 直仁","特異的モノクロナール抗体を用いた被修飾型ヒストンH3の局在と動態の解析","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"佐藤 優子,鯨井 智也,堀越 直樹,胡桃坂 仁志,木村 宏","ヒストンH4K20モノメチル化修飾特異的mintbodyを用いた生細胞イメージング","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"林 陽子,木村 宏","単一細胞解析によるヒストン修飾の細胞周期における変動と酵素郡の働き","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"半田 哲也,木村 宏","修飾特異的モノクローナル抗体を用いたヒストン修飾とRNAポリメラーゼ?の動態解析","第10回日本エピジェネティクス研究会年会",,,,,,2016,
"D. Muramatsu,H. Kimura,K. Kotoshiba,M. Tachibana,Y. Shinkai","Pericentric H3K9me3 Formation by HP1 Interaction-defective Histone Methyltransferase Suv39h1",,"Cell structure and function",,"Vol. 41","No. 2","pp. 145-152",2016,
"W. H. Shang,T. Hori,F. G. Westhorpe,K. M. Godek,A. Toyoda,S. Misu,N. Monma,K. Ikeo,C. W. Carroll,Y. Takami,A. Fujiyama,H. Kimura,A. F. Straight,T. Fukagawa","Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres",,"Nature communications",,"Vol. 7",,"pp. 13465",2016,
"木村宏,田代聡","ヌクレオソーム解析時代の幕開け",,"細胞工学","学研メディカル秀潤社","Vol. 35","No. 2","p. 66?69",2016,
"木村宏","遺伝子活性化のしくみの生きた細胞内での観察",,"パリティ","丸善出版株式会社","Vol. 31","No. 1","p. 70?72",2016,
"Hiroshi Kimura,Yuko Sato","DNA replication and histone modification",,"DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology",,,,"pp. 469-488",2016,
"Handoko, L.,Chang, J.,Kaczkowski, B.,Fujita, K.,Lizio, M.,Sato, Y.,Wakamori, M.,Hiroshi Kimura,Taniguchi, Y.,Yanagida, T.,Umehara, T.,Minoda, A.","Studying combinatorial histone modifications","Annual Meeting of the American-Society-for-Cell-Biology (ASCB)","MOLECULAR BIOLOGY OF THE CELL","AMER SOC CELL BIOLOGY","Vol. 27",,,2016,
"T. Urahama,A. Harada,K. Maehara,N. Horikoshi,K. Sato,Y. Sato,K. Shiraishi,N. Sugino,A. Osakabe,H. Tachiwana,W. Kagawa,H. Kimura,Y. Ohkawa,H. Kurumizaka","Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis",,"Epigenetics Chromatin",,"Vol. 9",,"pp. 2",2016,
"M. Oka,S. Mura,K. Yamada,P. Sangel,S. Hirata,K. Maehara,K. Kawakami,T. Tachibana,Y. Ohkawa,H. Kimura,Y. Yoneda","Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes",,"Elife",,"Vol. 5",,"pp. e09540",2016,
"E. Nakajima,K. Shimaji,T. Umegawachi,S. Tomida,H. Yoshida,N. Yoshimoto,S. Izawa,H. Kimura,M. Yamaguchi","The Histone Deacetylase Gene Rpd3 Is Required for Starvation Stress Resistance",,"PloS one",,"Vol. 11","No. 12","pp. e0167554",2016,
"N. M. Martins,J. H. Bergmann,N. Shono,H. Kimura,V. Larionov,H. Masumoto,W. C. Earnshaw","Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3",,"Molecular biology of the cell",,"Vol. 27","No. 1","pp. 177-96",2016,
"J. Y. Kaimori,K. Maehara,Y. Hayashi-Takanaka,A. Harada,M. Fukuda,S. Yamamoto,N. Ichimaru,T. Umehara,S. Yokoyama,R. Matsuda,T. Ikura,K. Nagao,C. Obuse,N. Nozaki,S. Takahara,T. Takao,Y. Ohkawa,H. Kimura,Y. Isaka","Histone H4 lysine 20 acetylation is associated with gene repression in human cells",,"Sci Rep",,"Vol. 6",,"pp. 24318",2016,
"K. Katsushima,A. Natsume,F. Ohka,K. Shinjo,A. Hatanaka,N. Ichimura,S. Sato,S. Takahashi,H. Kimura,Y. Totoki,T. Shibata,M. Naito,H. J. Kim,K. Miyata,K. Kataoka,Y. Kondo","Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment",,"Nat Commun",,"Vol. 7",,"pp. 13616",2016,
"M. Goto,N. Toda,K. Shimaji,D. N. Suong,N. Vo,H. Kimura,H. Yoshida,Y. H. Inoue,M. Yamaguchi","Polycomb-dependent nucleolus localization of Jumonji/Jarid2 during",,"Spermatogenesis",,"Vol. 6","No. 3","pp. e1232023",2016,
"Stunnenberg, H.G.,Abrignani, S.,Adams, D.,de Almeida, M.,Altucci, L.,Amin, V.,Amit, I.,Antonarakis, S.E.,Aparicio, S.,Arima, T.,Arrigoni, L.,Arts, R.,Asnafi, V.,Badosa, M.E.,Bae, J.-B.,Bassler, K.,Beck, S.,Berkman, B.,Bernstein, B.E.,Bilenky, M.,Bird, A.,Bock, C.,Boehm, B.,Bourque, G.,Breeze, C.E.,Brors, B.,Bujold, D.,Burren, O.,Bussemakers, M.J.,Butterworth, A.,Campo, E.,Carrillo-de-Santa-Pau, E.,Chadwick, L.,Chan, K.M.,Chen, W.,Cheung, T.H.,Chiapperino, L.,Choi, N.H.,Chung, H.-R.,Clarke, L.,Connors, J.M.,Cronet, P.,Danesh, J.,Dermitzakis, M.,Drewes, G.,Durek, P.,Dyke, S.,Dylag, T.,Eaves, C.J.,Ebert, P.,Eils, R.,Eils, J.,Ennis, C.A.,Enver, T.,Feingold, E.A.,Felder, B.,Ferguson-Smith, A.,Fitzgibbon, J.,Flicek, P.,Foo, R.S.-Y.,Fraser, P.,Frontini, M.,Furlong, E.,Gakkhar, S.,Gasparoni, N.,Gasparoni, G.,Geschwind, D.H.,Gla?ar, P.,Graf, T.,Grosveld, F.,Guan, X.-Y.,Guigo, R.,Gut, I.G.,Hamann, A.,Han, B.-G.,Harris, R.A.,Heath, S.,Helin, K.,Hengstler, J.G.,Heravi-Moussavi, A.,Herrup, K.,Hill, S.,Hilton, J.A.,Hitz, B.C.,Horsthemke, B.,Hu, M.,Hwang, J.-Y.,Ip, N.Y.,Ito, T.,Javierre, B.-M.,Jenko, S.,Jenuwein, T.,Joly, Y.,Jones, S.J.M.,Kanai, Y.,Kang, H.G.,Karsan, A.,Kiemer, A.K.,Kim, S.C.,Kim, B.-J.,Kim, H.-H.,Kimura, H.,Kinkley, S.,Klironomos, F.,Koh, I.-U.,Kostadima, M.,Kressler, C.,Kreuzhuber, R.,Kundaje, A.,K?ppers, R.,Larabell, C.,Lasko, P.,Lathrop, M.,Lee, D.H.S.,Lee, S.,Lehrach, H.,Leit?o, E.,Lengauer, T.,Lernmark, ?.,Leslie, R.D.,Leung, G.K.K.,Leung, D.,Loeffler, M.,Ma, Y.,Mai, A.,Manke, T.,Marcotte, E.R.,Marra, M.A.,Martens, J.H.A.,Martin-Subero, J.I.,Maschke, K.,Merten, C.,Milosavljevic, A.,Minucci, S.,Mitsuyama, T.,Moore, R.A.,M?ller, F.,Mungall, A.J.,Netea, M.G.,Nordstr?m, K.,Norstedt, I.,Okae, H.,Onuchic, V.,Ouellette, F.,Ouwehand, W.,Pagani, M.,Pancaldi, V.,Pap, T.,Pastinen, T.,Patel, R.,Paul, D.S.,Pazin, M.J.,Pelicci, P.G.,Phillips, A.G.,Polansky, J.,Porse, B.,Pospisilik, J.A.,Prabhakar, S.,Procaccini, D.C.,Radbruch, A.,Rajewsky, N.,Rakyan, V.,Reik, W.,Ren, B.,Richardson, D.,Richter, A.,Rico, D.,Roberts, D.J.,Rosenstiel, P.,Rothstein, M.,Salhab, A.,Sasaki, H.,Satterlee, J.S.,Sauer, S.,Schacht, C.,Schmidt, F.,Schmitz, G.,Schreiber, S.,Schr?der, C.,Sch?beler, D.,Schultze, J.L.,Schulyer, R.P.,Schulz, M.,Seifert, M.,Shirahige, K.,Siebert, R.,Sierocinski, T.,Siminoff, L.,Sinha, A.,Soranzo, N.,Spicuglia, S.,Spivakov, M.,Steidl, C.,Strattan, J.S.,Stratton, M.,S?dbeck, P.,Sun, H.,Suzuki, N.,Suzuki, Y.,Tanay, A.,Torrents, D.,Tyson, F.L.,Ulas, T.,Ullrich, S.,Ushijima, T.,Valencia, A.,Vellenga, E.,Vingron, M.,Wallace, C.,Wallner, S.,Walter, J.,Wang, H.,Weber, S.,Weiler, N.,Weller, A.,Weng, A.,Wilder, S.,Wiseman, S.M.,Wu, A.R.,Wu, Z.,Xiong, J.,Yamashita, Y.,Yang, X.,Yap, D.Y.,Yip, K.Y.,Yip, S.,Yoo, J.-I.,Zerbino, D.,Zipprich, G.,Hirst, M.,Hiroshi Kimura","The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery",,"Cell",,"Vol. 167","No. 5","pp. 1145-1149",2016,
"Kajitani, Takuya,Kato, Hiroaki,Chikashige, Yuji,Hiraoka, Yasushi,Hiroshi Kimura,Ohkawa, Yasuyuki,Nagao, Koji,Obuse, Chikashis,Hermand, Damien,Murakavii, Yota","Ser7 phosphorylation of RNAPII-CTD ensures on-chromatin retention of nascent ncRNAs, facilitating establishment and epigenetic inheritance of RNAi-depnendent heterochromatin formation",,"GENES & GENETIC SYSTEMS","GENETICS SOC JAPAN","Vol. 90","No. 6","pp. 360-360",2015,Dec.
"Yuko Sato,M. Mukai,H. Kimura","Histone Acetylation on Drosophila Polytene Chromosomes Visualized by Mintbody",,"Cytologia",,"vol. 80","no. 4","pp. 383-384",2015,Dec.
"原口徳子,木村宏,平岡泰","新・生細胞 蛍光イメージング",,"新・生細胞 蛍光イメージング","共立出版",,,,2015,Nov.
"Chan-I Chung,Yuki Ohmuro-Matsuyama,Yuko Sato,Hiroshi Kimura,Hiroshi Ueda","Development of intrabody-based FRET probe for monitoring histone H3 acetylation in living cells","Pacifichem 2015",,,,,,2015,Nov.
"木村宏","転写",,"生体の科学","医学書院","Vol. 6","No. 5","p. 468-469",2015,Oct.
"Hiroshi Kimura","Dynamics of actin-related protein 4 in living cell nucleus for dynamic chromatin regulation",,,,,,,2015,Sept.
"Koide, Shuhei,Takubo, Keiyo,Oshima, Motohiko,Miyagi, Satoru,Saraya, Atsunori,Wang, Changshan,Matsui, Hirotaka,Hiroshi Kimura,Shinkai, Yoichi,Suda, Toshio,Iwama, Atsushi","HISTONE METHYLTRANSFERASE SETDB1 REGULATES ENERGY METABOLISM IN HEMATOPOIETIC STEM AND PROGENITOR CELLS","44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH)","EXPERIMENTAL HEMATOLOGY","ELSEVIER SCIENCE INC","Vol. 43","No. 9","pp. S73-S73",2015,Sept.
"Kazumitsu Maehara,Akihito Harada,Yuko Sato,Masaki Matsumoto,Keiichi I. Nakayama,Hiroshi Kimura,Yasuyuki Ohkawa","Tissue-specific expression of histone H3 variants diversified after species separation",,"Epigenetics & Chromatin",,"vol. 8",,,2015,Sept.
"Yuma Ito,Hiroshi Kimura,Masahiko Harada,Kumiko Sakata-Sogawa,Makio Tokunaga","Dynamics of actin-related protein 4 in living cell nucleus for dynamic chromatin regulation","第53回日本生物物理学会年会",,,,,,2015,Sept.
"Yuma Ito,Tsubasa Isogaki,Hiroshi Kimura,Masahiko Harada,Kumiko Sakata-Sogawa,Makio Tokunaga","Intranuclear dynamics of INO80 chromatin remodeling complex by fluorescent recovery after photobleaching","第53回日本生物物理学会年会",,,,,,2015,Sept.
"Ito Y,Harata M,Kimura K,Sakata-Sogawa K,Tokunaga M","Dynamics of INO80 Chromatin Remodeling Complex by Live-cell Molecular Imaging.","International Symposium on Chromatin Structure, Dynamics, and Function",,,,,,2015,Aug.
"木村宏","単一細胞解析から明らかになった転写を制御するヒストン修飾の役割",,"細胞工学","学研メディカル秀潤社","Vol. 34","No. 3","pp. 271?272",2015,Feb.
"Akihito Harada,Kazumitsu Maehara,Yuko Sato,Daijiro Konno,Taro Tachibana,Hiroshi Kimura,Yasuyuki Ohkawa","Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle",,"Nucleic Acids Research",,"vol. 43","no. 2","pp. 775-786",2015,Jan.
"L. M. Rapkin,K. Ahmed,S. Dulev,R. Li,H. Kimura,A. M. Ishov,D. P. Bazett-Jones","The histone chaperone DAXX maintains the structural organization of heterochromatin domains",,"Epigenetics & chromatin",,"Vol. 8",,"pp. 44",2015,
"K. Ruan,T. G. Yamamoto,H. Asakawa,Y. Chikashige,H. Kimura,H. Masukata,T. Haraguchi,Y. Hiraoka","Histone H4 acetylation required for chromatin decompaction during DNA replication",,"Scientific reports",,"Vol. 5",,"pp. 12720",2015,
"K. Shimaji,T. Konishi,S. Tanaka,H. Yoshida,Y. Kato,Y. Ohkawa,T. Sato,M. Suyama,H. Kimura,M. Yamaguchi","Genomewide identification of target genes of histone methyltransferase dG9a during Drosophila embryogenesis",,"Genes to cells : devoted to molecular & cellular mechanisms",,"Vol. 20","No. 11","pp. 902-14",2015,
"Y. Shinchi,M. Hieda,Y. Nishioka,A. Matsumoto,Y. Yokoyama,H. Kimura,S. Matsuura,N. Matsuura","SUV420H2 suppresses breast cancer cell invasion through down regulation of the SH2 domain-containing focal adhesion protein tensin-3",,"Experimental cell research",,"Vol. 334","No. 1","pp. 90-9",2015,
"N. Shono,J. Ohzeki,K. Otake,N. M. Martins,T. Nagase,H. Kimura,V. Larionov,W. C. Earnshaw,H. Masumoto","CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly",,"Journal of cell science",,"Vol. 128","No. 24","pp. 4572-87",2015,
"S. Wada,H. Ideno,A. Shimada,T. Kamiunten,Y. Nakamura,K. Nakashima,H. Kimura,Y. Shinkai,M. Tachibana,A. Nifuji","H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro",,"Histochemistry and cell biology",,"Vol. 144","No. 1","pp. 13-20",2015,
"K. Wagatsuma,S. Tani-ichi,B. Liang,S. Shitara,K. Ishihara,M. Abe,H. Miyachi,S. Kitano,T. Hara,M. Nanno,H. Ishikawa,K. Sakimura,M. Nakao,H. Kimura,K. Ikuta","STAT5 Orchestrates Local Epigenetic Changes for Chromatin Accessibility and Rearrangements by Direct Binding to the TCRgamma Locus",,"Journal of immunology (Baltimore, Md. : 1950)",,"Vol. 195","No. 4","pp. 1804-14",2015,
"W. Yoshida,J. Tomikawa,M. Inaki,H. Kimura,M. Onodera,K. Hata,K. Nakabayashi","An insulator element located at the cyclin B1 interacting protein 1 gene locus is highly conserved among mammalian species",,"PloS one",,"Vol. 10","No. 6","pp. e0131204",2015,
"木村宏","ヒストン修飾と転写制御",,,,,,,2015,
"Y. Abe,R. Rozqie,Y. Matsumura,T. Kawamura,R. Nakaki,Y. Tsurutani,K. Tanimura-Inagaki,A. Shiono,K. Magoori,K. Nakamura,S. Ogi,S. Kajimura,H. Kimura,T. Tanaka","JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis",,,,"Vol. 6",,"pp. 7052",2015,
"木村宏","ストレス対応のクロマチンダイナミクス",,,,,,,2015,
"木村宏","細胞周期・メタボリズムとヒストン修飾動態",,,,,,,2015,
"J. D. Dias,T. Rito,E. Torlai Triglia,A. Kukalev,C. Ferrai,M. Chotalia,E. Brookes,H. Kimura,A. Pombo","Methylation of RNA polymerase 竇｡ non-cosensus Lysine residues marks early mammalian cells",,"eLife",,"Vol. 4",,,2015,
"Hiroshi Kimura","Kinetics of Histone and RNA Polymerase ? Modifications during Transcriptional Activation",,,,,,,2015,
"Hiroshi Kimura","Histone modifications associated with transcriptional activation of coding and non-coding DNA in living cells",,,,,,,2015,
"A. Harada,K. Maehara,Y. Sato,D. Konno,T. Tachibana,H. Kimura,Y. Ohkawa","Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle",,"Nucleic acids research",,"Vol. 43","No. 2","pp. 775-86",2015,
"Hiroshi Kimura","Chromatin modification dynamics in transcriptional activation",,,,,,,2015,
"Hiroshi Kimura","Detecting protein function in living cells:From mobility analysis to posttranslational modification tracking",,,,,,,2015,
"Yuma Ito,Hiroshi Kimura,Hitoshi Kurumizaka,Masahiko Harada,Kumiko Sakata-Sogawa,Makio Tokunaga","Integrated Imaging Approach to the Study of Chromatin Dynamics","International Symposium on Chromatin Structure Dynamics,and Function",,,,,,2015,
"Kazumitsu Maehara,Akihito Hrada,Yuko Sato,Masaki Matsumoto,Keiichi I.Nakayama,Hiroshi Kimura,Yasuyuki Ohkawa","The Diversity of mouse histone H3 variants","International Symposium on Chromatin Structure Dynamics,and Function",,,,,,2015,
"Brian P.English,Tatsuya Morisaki,Kumiko Sakata-Sogawa,Makio Tokunaga,Naohito Nozaki,Hiroshi Kimura,Timothee Lionnet Timothy J.Stasevich","Towards Single-Gene Imaging of Endogenous Histone and RNA Polumerase ?Modifications in Living Cells","International Symposium on Chromatin Structure Dynamics,and Function",,,,,,2015,