"Yuto Honda,Shuhei Nagao,Hiroaki Kinoh,Nozomi Matsudaira,Xueying Liu,Takahiro Nomoto,Anjaneyulu Dirisala,Yutaka Miura,Kazunori Kataoka,Nobuhiro Nishiyama","集束超音波と高分子複合体を組み合わせた脳選択的AAV送達システムの構築","第４４回日本バイオマテリアル学会大会",,,,,,2023,Nov.
"Nobuhiro Nishiyama","Development of Synthetic Polymer-based Nanomachine for Cancer Diagnosis and Therapy",,"Yakugaku Zasshi",,"Vol. 143","No. 5","pp. 443-447",2023,May
"Nobuhiro Nishiyama","精密高分子合成を基盤とするスマートナノマシンの創製","高分子進化工学 第一回公開シンポジウム",,,,,,2023,Feb.
"Nobuhiro Nishiyama","精密合成ポリマー技術を基盤としたナノメディシンの研究開発","製薬協 DDSコンソーシアム",,,,,,2022,Dec.
"Haochen Guo,Xu Wen,Takahiro Nomoto,Kaito Kanamori,Yan Ming Voon,Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters.",,"Biomaterials",,,,"  in press (掲載決定、オンライン版掲載済み)",2022,Dec.
"Nobuhiro Nishiyama","Novel core-shell design for smart polymeric micelles","International Symposium on Advanced Biomaterials",,,,,,2022,Nov.
"Nozomi Matsudaira,Yuto Honda,Shuhei Nagao,Hiroaki Kinoh,Takahiro Nomoto,Xueying Liu,Anjaneyulu Dirisala,Yutaka Miura,Kazunori Kataoka,Nobuhiro Nishiyama","腫瘍細胞標的機能を備えた全身投与型アデノ随伴ウイルス(AAV)三元系複合体の開発",,,,,,,2022,Nov.
"Nobuhiro Nishiyama","高分子ミセルによる核酸・ペプチド・タンパク質医薬品の送達技術に関する研究","日本薬物動態学会 第37回年会 横浜",,,,,,2022,Nov.
"Anudari Batbayar,Haochen Guo,Takahiro Nomoto,Yan Ming Voon,Nobuhiro Nishiyama","Developing of Ovalbumin-Loaded Ternary Complexes Utilizing Tannic Acid and Phenylboronic Acid Conjugated Polymers for Cancer Immunotherapy","第４４回日本バイオマテリアル学会大会",,,,,,2022,Nov.
"Nobuhiro Nishiyama","Sequential self-assembly bio-building blocks based on polyphenol materials for efficient biomolecules delivery","第４４回日本バイオマテリアル学会大会, 日韓バイオマテリアル若手交流AWARDセッション",,,,,,2022,Nov.
"Takahiro Nomoto,Kana Komoto,Tomoya Nagano,Takuya Ishii,Haochen Guo,Yuto Honda,Shun-ichiro OGURA,Masahiro Ishizuka,Nobuhiro Nishiyama","Polymeric iron chelators for enhancing 5-aminolevulinic acid-induced photodynamic therapy",,,,"Vol. 114","No. 3","pp. 1086-1094",2022,Nov.
"Nobuhiro Nishiyama","Development of polymer conjugates for drug delivery system targeting tumor-associated amino acid transporters","第４４回日本バイオマテリアル学会大会",,,,,,2022,Nov.
"Nobuhiro Nishiyama","バイオ医薬品送達システムを指向した高分子ミセルのコア-シェル設計","超細胞・DDS研究開発部門シンポジウム",,,,,,2022,Oct.
"Haochen Guo,Takahiro Nomoto,Hiroaki Kinoh,Jun Ishihara,Nobuhiro Nishiyama","Polymeric Iron Chelator Modulating Tumor Immune Microenvironment","第８１回癌学会学術総会",,,,,,2022,Oct.
"Nobuhiro Nishiyama","精密高分子設計に基づくナノDDSの設計と光治療への応用","第43回日本レーザー医学会総会",,,,,,2022,Oct.
"Yuto Honda,Sayaka Onodera,Hiroyasu Takemoto,Faizah Noor,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Yudi Sun,Yutaka Miura,Nobuhiro Nishiyama","Thermo-responsive polymer-siRNA conjugates enabling artificial control of gene silencing around body temperature",,"Pharmaceutical Research",,"Vol. 40","No. 1","pp. 157-165",2022,Oct.
"Yijung Sung,Haochen Guo,Aria Ghasemizadeh,Xin Shen,Wanphiwat Chintrakulchai,Motoaki Kobayashi,Masahiro Toyoda,Koichi Ogi,Junya Michinishi,Tokoyuki Ohtake,Makoto Matsui,Yuto Honda,Takahiro Nomoto,Hiroyasu Takemoto,Yutaka Miura,Nobuhiro Nishiyama","Cancerous pH-responsive polycarboxybetaine-coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model",,"Cancer Science",,"Vol. 113","No. 12","pp. 4339-4349",2022,Oct.
"Xue Xie,Yuta Kurashina,Makoto Matsui,Takahiro Nomoto,Munenari Itoh,Hirotaka J Okano,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Transdermal delivery of bFGF with sonophoresis facilitated by chitosan nanocarriers",,"Elsevier",,"vol. 75",,"  103675",2022,Sept.
"Aziz Awaad,Hiroyasu Takemoto,Muneaki Iizuka,Koichi Ogi,Yuki Mochida,Abdul-Hackam Ranneh,Masahiro Toyoda,Makoto Matsui,Takahiro Nomoto,Yuto Honda,Kotaro Hayashi,Keishiro Tomoda,Tomoyuki Ohtake,Yutaka Miura,Nobuhiro Nishiyama","Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration",,"Journal of Controlled Release",,"Vol. 346",,"pp. 392-404",2022,May
"Yuto Honda,Syuhei Nagao,Hiroaki Kinoh,Takahiro Nomoto,Liu Xueying,Dirisala Anjaneyulu,Makoto Matsui,Yutaka Miura,Kazunori Kataoka,Nobuhiro Nishiyama","アデノ随伴ウイルス（AAV）の中和抗体回避および活性を向上させるAAV内包三元系複合体","日本薬学会第142回年会",,,,,,2022,Mar.
"Nobuhiro Nishiyama","高分子の精密設計に基づくがん診断・治療用ナノマシンの創製","日本薬学会第142年会 一般シンポジウムS29  元素の力で切り拓く新時代の創薬イノベーション~多元素化合物による 革新的生物機能分子の創製",,,,,,2022,Mar.
"Takumi Matsuo,Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸導入高分子で構築されたCas9 RNPデリバリーシステムの開発","日本薬学会第142回年会",,,,,,2022,Mar.
"Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Keita Ando,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Quantitative analysis of acoustic pressure for sonophoresis and its effect on transdermal penetration",,,,,,,2022,Feb.
"Nobuhiro Nishiyama","精密高分子設計を基盤とする中分子バイオ医薬品のDDS開発","第17回 日本がん分子標的治療学会 TRワークショップ 次世代がん創薬としての中分子領域薬の開発フロンティア",,,,,,2022,Jan.
"Guo H.,Nomoto T.,Muttaqien S.E.,Sun X.,Komoto K.,Matsui M.,Miura Y.,Nishiyama N.","A polymeric iron chelator enhancing pro-oxidant antitumor efficacy of vitamin C by inhibiting extracellular Fenton reaction",,"Molecular Pharmaceutics",,"Vol. 18","Issue 12",,2021,Dec.
"Nobuhiro Nishiyama","Novel core-shell design for smart polymeric micelles","Materials Research Meeting 2021 (MRM2021)",,,,,,2021,Dec.
"Yuto Honda*,Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yutaka Miura,Nobuhiro Nishiyama*","Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity",,"ACS Applied Materials and Interfaces",,"Vol. 13","No. 46","pp. 54850?54859",2021,Nov.
"Yuto Honda,Naoki Yamada,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","グルタミントランスポーターを高密度で発現しているがん細胞を認識する機能性高分子の開発","第43回日本バイオマテリアル学会大会",,,,,,2021,Nov.
"Syuhei Nagao,Yuto Honda,Hiroaki Kinoh,Takahiro Nomoto,Liu Xueying,Dirisala Anjaneyulu,Makoto Matsui,Yutaka Miura,Kazunori Kataoka,Nobuhiro Nishiyama","アデノ随伴ウイルス(AAV)中和抗体回避を可能にする全身投与型AAV搭載三元系複合体の開発","第43回日本バイオマテリアル学会大会",,,,,,2021,Nov.
"Takumi Matsuo,Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸導入高分子の自己会合によって構成されたCas9 RNPデリバリーシステムの開発","第11回CSJ化学フェスタ2021",,,,,,2021,Oct.
"Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Measurement and calculation of acoustic pressure on the effect of transdermal penetration by sonophoresis","The 42nd Symposium on Ultrasonic Electronics",,,,,,2021,Oct.
"Takumi Matsuo,Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸導入高分子で構築された自己会合型Cas9 RNP送達システムの開発","第70回高分子討論会",,,,,,2021,Sept.
"Haochen Guo,Takahiro Nomoto,Makoto Matsui,Yan Ming Voon,Yijung Sung,Yutaka Miura,Nobuhiro Nishiyama","高分子鉄キレート剤を利用した腫瘍免疫逃避環境の克服","第70回高分子討論会",,,,,,2021,Sept.
"Koichi Usukura,Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","官能基が異なるボロン酸導入高分子とタンニン酸で構成されたタンパク質三元系複合体の安定性評価","第70回高分子討論会",,,,,,2021,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Kakeru Konarita,Makoto Matsui,Nobuhiro Nishiyama","Synthesis of functional polymers boosting therapeutic potential of p-boronophenylalanine and analysis of the effect of their physicochemical properties on pharmacokinetics","19th International Congress on Neutron Capture Therapy (19th ICNCT)",,,,,,2021,Sept.
"Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","効率的なタンパク質送達を指向したタンニン酸とフェニルボロン酸導入高分子で構成されたタンパク質内包三元系複合体の構築","第70回高分子討論会",,,,,,2021,Sept.
"Jing Liu,Cabral Horacio,Bing Song,Ichio Aoki,Zhouyun Chen,Nobuhiro Nishiyama,Yuan Huang,Kazunori Kataoka,Peng Mi","Nanoprobe-based magnetic resonance imaging of hypoxia predicts responses to radiotherapy, immunotherapy, and sensitizing treatments in pancreatic tumors",,"ACS Nano",,"Vol. 15","No. 8","pp. 13526?13538",2021,Aug.
"Yuma Ikeda,Mariko Orioka,Takahiro Nomoto,Yuki Hiruma,Nobuhiro Nishiyama,Daniel Citterio","Differentialeffect of azetidine substitution in firefly luciferin analogues",,"ChemBioChem",,"Vol. 22","No. 21","pp. 3067-3074",2021,Aug.
"Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Construction of sequential self-assembled protein ternary complex utilizing boronic acid conjugated-polymer and tannic acid for protein delivery","ACS Fall 2021",,,,,,2021,Aug.
"Yuto Honda*,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Kaori Taniwaki,Haochen Guo,Yutaka Miura,Nobuhiro Nishiyama*","Systemically Applicable Glutamine-Functionalized Polymer Exerting Multivalent Interaction with Tumors Overexpressing ASCT2.",,"ACS Applied Bio Materials",,"Vol. 4","No. 10","pp. 7402?7407",2021,Aug.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Kakeru Konarita,Makoto Matsui,Nobuhiro Nishiyama","側鎖に糖構造を有する高分子とボロノフェニルアラニンから構成される薬物送達システムの設計","第17回日本中性子捕捉療法学会学術大会",,,,,,2021,July
"Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Effect of sonophoresis with various nanoparticles on transdermal drug delivery","The 12th International Conference on the Science and Technology for Advanced Ceramics",,,,,,2021,July
"Masayoshi Tanaka,Mirei Hayashi,Roach Lucien,Yuka Kiriki,Tetsuya Kadonosono,Takahiro Nomoto,Nobuhiro Nishiyama,Choi Jonghoon,Critchley Kevin,D. Evans Stephen,Mina Okochi","Synthesis of near-infrared absorbing triangular Au nanoplates using biomineralisation peptides",,"ACTA Biomaterialia",,,,,2021,June
"Takahiro Nomoto,Kakeru Konarita,Minoru Suzuki,Makoto Matsui,Nobuhiro Nishiyama","ポリビニルアルコールを利用したボロノフェニルアラニンの中性子捕捉療法における治療効果向上","第37回日本DDS学会学術集会",,,,,,2021,June
"Haochen Guo,Takahiro Nomoto,Makoto Matsui,Kana Komoto,S Muttaqien,Yutaka Miura,Nobuhiro Nishiyama","高分子鉄キレート剤を用いた腫瘍内鉄イオン制御とそのアスコルビン酸の抗腫瘍効果への影響に関する検討","第37回日本DDS学会学術集会",,,,,,2021,June
"Ohashi Ryotaro,Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸導入高分子で構成されるオボアルブミン封入三元系複合体の構築とがん免疫療法への応用","第37回日本DDS学会学術集会",,,,,,2021,June
"Takumi Matsuo,Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸修飾高分子からなるCRISPR/Casタンパク質デリバリーシステムの開発","第37回日本DDS学会学術集会",,,,,,2021,June
"Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸導入高分子の自己会合によって形成されたナノリアクターの酵素プロドラッグ療法への応用","第31回バイオ・高分子シンポジウム",,,,,,2021,June
"Yuto Honda,Natsumi Fukuhara,Nao Ukita,Makoto Matsui,Satoshi Ohno,Takahiro Nomoto,Nobuhiro Nishiyama,Katsuyuki Hoshina,Yutaka Miura","ボロン酸エステルを介したスタチン内包高分子型ミセルの構築および薬理効果","第37回日本DDS学会学術集会",,,,,,2021,June
"Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka MiuraNobuhiro Nishiyama,Nobuhiro Nishiyama","タンニン酸とフェニルボロン酸導入高分子から成る自己会合型ナノリアクターの構築および酵素プロドラッグ療法への応用","第37回日本DDS学会学術集会",,,,,,2021,June
"Syuhei Nagao,Yuto Honda,Hiroaki Kinoh,Takahiro Nomoto,Liu Xueying,Dirisala Anjaneyulu,Makoto Matsui,Yutaka Miura,Kazunori Kataoka,Nobuhiro Nishiyama","アデノ随伴ウイルス(AAV)ベクターの中和抗体および副作用を克服するAAV/タンニン酸/ボロン酸導入高分子三元系複合体の構築","第37回日本DDS学会学術集会",,,,,,2021,June
"Kakeru Konarita,Takahiro Nomoto,Kaito Kanamori,Minoru Suzuki,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Poly(vinyl alcohol)と D-4-boronophenylalanine から構成される 薬物送達システムによるホウ素中性子捕捉療法の検討","第70回高分子学会年次大会",,,,,,2021,May
"Takahiro Nomoto,Ying Yao,Yukiya Inoue,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy",,"Journal of Controlled Release",,"Vol. 332",,"pp. 184-193",2021,Feb.
"Komoto Kana,Takahiro Nomoto,Muttaqien S.,Takemoto Hiroyasu,Matsui Makoto,Miura Yutaka,Nishiyama Nobuhiro","Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine",,"Cancer Science",,"Vol. 112","No. 1","pp. 410-421",2021,Jan.
"Nobuhiro Nishiyama","機能性ポリマーの精密設計に基づく ナノメディシンの開発","第15回理研「バイオものづくり」シンポジウム",,,,,,2020,Dec.
"S Muttaqien,Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Photodynamic therapy using LCST polymers exerting pH-responsive isothermal phase transition",,"Journal of Controlled Release",,"Vol. 328",,"pp. 608-616",2020,Dec.
"Nobuhiro Nishiyama","Shell and core design of polymeric micelles for delivery of biopharmaceuticals","A3 Foresight & 5 Star Alliance Joint Workyoushop",,,,,,2020,Dec.
"Takahiro Nomoto,Nobuhiro Nishiyama","ポリビニルアルコールによるBNCT治療効果向上について",,"Isotope News",,,"No. 772",,2020,Dec.
"Nobuhiro Nishiyama","pH反応性ポリマーとナノ粒子","第5回 MRIアライアンス・シンポジウム",,,,,,2020,Nov.
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Nobuhiro Nishiyama","多価環状RGDペプチド担持高分子型光増感剤によるphotochemical internalizationの検討","LASER WEEK IN KOCHI",,,,,,2020,Oct.
"Nobuhiro Nishiyama","高分子の精密設計に基づくナノDDSの開発","お茶の水がん学アカデミア第 162 回集会",,,,,,2020,Oct.
"Xiaohang Sun,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Haochen Guo,Yudi Sun,Yutaka Miura,Nobuhiro Nishiyama","Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives",,"Journal of Controlled Release",,,,,2020,Sept.
"Yuto Honda,Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yuka Kaihara,Yutaka Miura,Nobuhiro Nishiyama","Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery",,"Biomacromolecules",,"Vol. 21","No. 9","pp. 3826-3835",2020,Sept.
"Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","高分子修飾によるsiRNA周囲の空間支配と薬理機構制御",,,,,,,2020,Sept.
"Masahiro Toyoda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","腫瘍内pH応答性の獲得を目指した高分子ベタイン内の両イオン性基の種類・間隔の検討",,,,,,,2020,Sept.
"Nobuhiro Nishiyama","高分子の精密設計に基づくホウ素薬剤送達システムの開発","令和2 年度京都大学複合原子力科学研究所専門研究会「京都大学複合原子力科学研究所におけるBNCT 研究の多様化・高度化に関する研究会」",,,,,,2020,Sept.
"Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Transdermal Delivery of Large Nanoparticles via Ultrasonic Irradiation in Low-Frequency Range","2020 International Ultrasonics Symposium(IUS2020)","Proceedings of IUS 2020",,,,"  C1P-24-1150",2020,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Kakeru Konarita,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Development of functional polymers to boost therapeutic potential of boronophenylalanine in neutron capture therapy","第69回高分子討論会",,,,,,2020,Sept.
"Kana Komoto,Takahiro Nomoto,S Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","がん鉄キレート療法のための効率的な除鉄を実現する機能性高分子の開発","第69回高分子討論会",,,,,,2020,Sept.
"I Dewa Agung Panji Dwipayana,Yuto Honda,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Development of a versatile drug delivery system using tannic acid and boronic acid-conjugated polymer","第69回高分子討論会",,,,,,2020,Sept.
"ムツタキンシャイクリザルエル,Yutaka Miura,Haochen Guo,Takahiro Nomoto,Kana Komoto,S Muttaqien,Xiaohang Sun,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Polymeric iron-chelators for improving high- dose vitamin C therapy","第69回高分子討論会",,,,,,2020,Sept.
"Yudi Sun,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","ASO-分岐PEG結合体を内包する小分子キャリアの開発および機能評価",,,,,,,2020,Sept.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama",""環状アセタール構造に基づくゲムシタビン担持型高分子の開発とその機能評価 および副作用低減"","第36回日本DDS学会学術集会",,,,,,2020,Aug.
"Haochen Guo,Takahiro Nomoto,Kana Komoto,S Muttaqien,Xiaohang Sun,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Effect of polymeric iron-chelators on high-dose vitamin C therapy","第36回日本DDS学会学術集会",,,,,,2020,Aug.
"Takahiro Nomoto,Yuto Honda,Yuka Kaihara,Hiroaki Kinoh,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","タンニン酸とボロン酸ケミストリーを利用した高分子複合体の簡便調製法","第 3 回 COI 学術交流会",,,,,,2020,July
"Guo Haochen,Takahiro Nomoto,Kana Komoto,Sun Xiaohang,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Development of polymeric iron-chelators for enhancing high-dose vitamin C therapy","第 3 回 COI 学術交流会",,,,,,2020,July
"Takahiro Nomoto,Sjaikhurrizal El Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Photodynamic therapy utilizing functional polymers that exert pH-responsive isothermal phase transition","ICPST-36",,,,,,2020,June
"Nobuhiro Nishiyama","機能性高分子の精密設計に基づく医療ナノマシンの創製","COINSセミナー#52",,,,,,2020,May
"Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama",""環状アセタール構造を介したゲムシタビンのポリアミノ酸への導入と薬効増大 および副作用低減"",,,,,,,2020,May
"Masahiro Toyoda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","高分子ベタイン内のイオン性基の種類・間隔の制御と腫瘍内pH応答性への展開","第69回高分子学会年次大会",,,,,,2020,May
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(vinyl alcohol) for enhancing therapeutic effects of p-boronophenylalanine in neutron capture therapy","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb.
"Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Iron chelation cancer therapy using functional polymers targeting tumors","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb.
"Yuto Honda,Takahiro NOMOTO,Makoto MATSUI,Hiroyasu TAKEMOTO,Yuka KAIHARA,Yutaka MIURA,Nobuhiro NISHIYAMA","Development of intracellular pH- responsive protein delivery system utilizing boronic acid-conjugated polymer and tannic acid","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,M Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism",,"Science Advances",,"Vol. 6","No. 4",,2020,Jan.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Gyomon Ryu,Masahiro Toyoda,Yuto Honda,Kaori Taniwaki,Naoki Yamada,Junhyun Kim,Keishiro Tomoda,Nobuhiro Nishiyama","Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects",,"Biomaterials",,"Vol. 235",,,2020,
"Yuma Ikeda,Takahiro Nomoto,Yuki Hiruta,Nobuhiro Nishiyama,Daniel Citterio","Ring-Fused Firefly Luciferins: Expanded Palette of Near-Infrared Emitting Bioluminescent Substrates",,"Analytical Chemistry",,"Vol. 92","No. 6","pp. 4235-4243",2020,
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Photosensitizer delivery to tumor cells and tumor-associated vasculature using functional polymers","7th International ALA and Prophyrin Symposium (IAPS7)",,,,,,2019,Dec.
"Nobuhiro Nishiyama","Development of Smart Nanomachines for Minimally Invasive Cancer Treatment","第6回COINSシンポジウム",,,,,,2019,Dec.
"Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yuka Kaihara,Yutaka Miura,Nobuhiro Nishiyama","ボロン酸導入高分子とタンニン酸を用いた細胞内環境応答タンパク質送達システムの構築","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","環状アセタール構造に基づくゲムシタビンの高分子修飾と制がん効果増大及び副作用低減","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","生体適合性高分子とボロノフェニルアラニンから構成される中性子捕捉療法用代謝制御型ホウ素送達システム","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","がん治療のための効率的な生体内の除鉄を実現する機能性高分子の開発","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Nobuhiro Nishiyama","機能性高分子の精密設計に基づく医療ナノマシンの創製","“ニューモダリティと有機合成化学”研究部会 第2回勉強会",,,,,,2019,Oct.
"Hiroyasu Takemoto,Muhammad Aziz,Ranneh Hackam,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","腫瘍内pH応答性高分子ベタインの設計と被覆ナノ粒子への展開","第68回高分子討論会",,,,,,2019,Sept.
"Kaito Kanamori,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","BPA delivery system utilizing sugar-modified polymers forming stable boronate esters","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)",,,,,2019,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Makoto Matsui,Hiroyasu Takemoto,Nobuhiro Nishiyama","Boosting Therapeutic Potential of p-Boronophenylalanine Using Biocompatible Polymers","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)",,,,,,2019,Sept.
"Takahiro Nomoto,S Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","腫瘍内低pH環境に応答して親水-疎水相転移挙動を示す高分子コンジュゲート型光増感剤","PhotoDynamic Medicine 2019",,,,,,2019,Sept.
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","温度応答性高分子-siRNA結合体の合成と外部刺激によるsiRNAの生物活性制御","第68回高分子討論会",,,,,,2019,Sept.
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん細胞の高密度グルタミントランスポーターと選 択的な相互作用を示す機能性高分子の開発","第68回高分子討論会",,,,,,2019,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","生体適合性高分子とp-boronophenylalanineから構成されるホウ素送達システムの開発と構成高分子の物性が体内動態と治療効果に与える影響に関する考察","第16回日本中性子捕捉療法学会",,,,,,2019,Sept.
"Nobuhiro Nishiyama","Design of functional polymers for smart nanomedicine","Liposome Research Days (LRD2019) in Sapporo",,,,,,2019,Sept.
"Nobuhiro Nishiyama","精密高分子設計に基づくDDSとPDT応用","PhotoDynamic Medicine 2019 (PDM2019)",,,,,,2019,Sept.
"Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","がん治療を指向した生体内鉄イオンをキレートする機能性高分子の開発","第35回日本DDS学会学術集会",,,,,,2019,July
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","温度応答性高分子-siRNA結合体とのポリイオンコンプレックス形成と外部刺激によるsiRNA の薬効制御",,,,,,,2019,July
"Hiroyasu Takemoto,Muhammad Aziz,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","腫瘍 pH 応答性高分子ベタインの開発とナノ粒子のがん送達への展開","第35回日本DDS学会学術集会",,,,,,2019,July
"Nobuhiro Nishiyama,Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui","Development of polymeric iron chelator for cancer therapy","The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics",,,,,,2019,July
"Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","ボロン酸エステルを利用したホウ素薬物送達キャリアの開発","第35回日本DDS学会学術集会",,,,,,2019,July
"Makoto Matsui,Yuka Kaihara,Hiroyasu Takemoto,Takahiro Nomoto,Nobuhiro Nishiyama","薬物送達技術を応用した新規骨折治療法の開発","第35回日本DDS学会学術集会",,,,,,2019,July
"Wanaporn Yimchuen,Tetsuya Kadonosono,Shinichi Sato,Takahiro Nomoto,Kyra See,Hiroyuki Nakamura,Nobuhiro Nishiyama,Shinae Kizaka-Kondoh","Development of photoimmunotherapy probe using a small antibody mimetic with structurally constrained anti-HER2 CDR peptides","11th International Peptide Symposium",,,,,,2019,June
"Nobuhiro Nishiyama","核酸医薬のためのDDS",,"医学のあゆみ",,"Vol. 269","No. 5","pp. 347-351",2019,May
"Y Horise,M Maeda,Y Konishi,J Okamoto,S Ikuta,Y Okamoto,H Ishii,S Umemura,T Ueyama,S Tamano,A Sofuni,K Takemae,K Masamune,H Iseki,Nobuhiro Nishiyama,K Kataoka,Y Muragaki","Sonodynamic therapy with anticancer micelles and high-intensity focused ultrasound in treatment of canine cancer",,"Frontiers in Pharmacology",,"Vol. 10",,"p. 545",2019,May
"Hiroyasu Takemoto,Wang, Chih-Ling,Takahiro Nomoto,Matsui, Makoto,Tomoda, Keishiro,Nobuhiro Nishiyama","Pyruvate responsiveness based on α-oxohydrazone formation for intracellular siRNA release from polyion complex-based carriers",,"Biomacromolecules",,,,,2019,May
"Masahiro Toyoda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","腫瘍内pH応答性高分子ベタイン内のイオン性基間距離の検討","第68回高分子学会年次大会",,,,,,2019,May
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","ポリイオンコンプレックスを利用した温度応答性高分子-siRNA結合体の細胞内導入と外部刺激によるsiRNAの生物活性制御","第68回高分子学会年次大会",,,,,,2019,May
"Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","糖修飾高分子とホウ素薬物から構成される薬物送達システムの開発","第68回高分子学会年次大会",,,,,,2019,May
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん細胞の高密度グルタミントランスポーターを標的として選択的な相互作用を示す機能性高分子の開発","第68回高分子学会年次大会",,,,,,2019,May
"Watanabe, Sumiyo,Hayashi, Kotaro,Toh, Kazuko,Kim Hyun Jin,Liu, Xueying,Chaya, Hiroyuki,Fukushima, Shigeto,Katsushima, Keisuke,Kondo, Yutaka,Uchida, Satoshi,Ogura, Satomi,Takahiro Nomoto,Hiroyasu Takemoto,Cabral, Horacio,Kinoh, Hiroaki,Tanaka, Hiroyoshi,Kano, Mitsunobu,Matsumoto, Yu,Fukuhama, Hiroshi,Uchida, Shyunya,Nagaku, Masaomi,Osada, Kensuke,Nobuhiro Nishiyama,Miyata, Kanjiro,Kataoka, Kazunori","In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers",,"Nature Communications",,,,,2019,Apr.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Metabolism-controlled boron delivery systems composed of biocompatible polymers and boronophenylalanine for neutron capture therapy",,"Abstracts of Papers of the American Chemical Society",,,,,2019,
"Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Boron Delivery Using Sugar-Modified Polymers for Neutron Capture Therapy","The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics",,,,,,2019,
"Nobuhiro Nishiyama","機能性高分子の精密設計に基づくナノメディシンの創製","日本接着学会東北支部講演会2018",,,,,,2018,Dec.
"Yuka Kaihara,Makoto Matsui,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Development of novel drug delivery system for enhancing bone regeneration in bone fracture model mouse","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Conjugation of siRNA and a polymer with coil-globule transition property for control of siRNA activity around body temperature","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of poly(amino acid)-based carrier that loads gemcitabine via reversible linkage and its evaluation using pancreatic cancer model","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Sun Xiaohang,Taknaori Inaba,Kazuki Ohsakama,Mika Shishido,Hiroki Yoshioka,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","Development of degradable poly(ethylene glycol)(PEG) derivatives for suppressing cellular vacuolations","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Sjaikhurrizal El Muttaqien,松井 誠,武元 宏泰,野本 貴 大,友田 敬士郎,西山 伸宏","Poly(N-isopropylacrylamide) derivatives exering remarkable LCST shift in response to slight pH chnge via detachment of hydrophilic acid-labile moiety","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Hiroyasu Takemoto,Abdul-Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","Ethylenediamine-based polyzwitterion that becomes cationic at tumorous pH for effective tumor accumulation of the coated nanomaterials","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Tsukasa Chida,Yutaka Miura,Cabral Horacio,Takahiro Nomoto,Kazunori Kataoka,Nobuhiro Nishiyama","Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release",,"J. Control. Release",,"Vol. 292",,"pp. 130-140",2018,Dec.
"Yuto Honda,Naoki Yamada,Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism.","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety",,"BIOMACROMOLECULES",,"Vol. 20","No. 4","pp. 1493-1504",2018,Dec.
"Nobuhiro Nishiyama","Smart nanomedicines based on the design of functional polymer","International Conference on Emerging Healthcare Materials 2018 (ICEHM2018)",,,,,,2018,Nov.
"Nobuhiro Nishiyama","機能性高分子の設計に基づくがん診断・治療システムの開発","第35回医用高分子研究会講座",,,,,,2018,Nov.
"Nobuhiro Nishiyama","機能性ポリマーの精密設計に基づく スマート機能型ナノメディシンの創製","第56回日本癌治療学会学術集会",,,,,,2018,Oct.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Metabolism-controlled boron delivery systems composed of p-boronophenylalanine and poly(vinyl alcohol)","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct.
"Ying Yao,Takahiro Nomoto,Yukiya Inoue,Minoru Suzuki,Makoto Matsui,Hiroyasu Takemoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced tumor-targeted delivery of p-boronophenylalanine using fructose-functionalized polymers for boron neutron capture therapy","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct.
"Takahiro Nomoto,Nobuhiro Nishiyama","Design of drug delivery systems for physical energy-induced chemical surgery",,"Biomaterials","Elsevier","Volume 178",,"pp. 583-596",2018,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","生体適合性機能性高分子によるボロノフェニルアラニンの代謝制御と治療効果の向上","第15回日本中性子捕捉療法学会学術大会",,,,,,2018,Sept.
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Multiple cyclic RGD-conjugated functional polymers controlling intratumoral distribution of IRDye 700DX","Photodynamic Therapy and Photodiagnosis Update 2018",,,,,,2018,Sept.
"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","Size-regulated siRNA carriers from small complex loading single siRNA molecule for systemic delivery to tumor tissue","第77回日本癌学会学術総会",,,,,,2018,Sept.
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of gemcitabine-conjugated poly(amino acid) and its evaluation using pancreatic tumor model","第67回高分子討論会",,,,,,2018,Sept.
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","グルタミン代謝が亢進したがん細胞の高密度グルタ ミントランスポーターを認識してアフィニティを示す機能性高 分子","第67回高分子討論会",,,,,,2018,Sept.
"Sjaikhurrizal El Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor","256th ACS National Meeting & Exposition",,,,,,2018,Aug.
"R. Toshiyama R,M. Konno,H. Eguchi,H. Takemoto,T. Noda,A. Asai,J. Koseki,N. Haraguchi,Y. Ueda,K. Matsushita,K. Asukai,T. Ohashi,Y. Iwagami,D. Yamada,D. Sakai,T. Asaoka,T. Kudo,K. Kawamoto,K. Gotoh,S. Kobayashi,T. Satoh,Y. Doki,N. Nishiyama,M. Mori,H. Ishii","Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells",,"Oncogene",,"Vol. 38","No. 2","pp. 244-260",2018,Aug.
"Hiroyasu Takemoto,Abduhl Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials","256th ACS National Meeting & Exposition",,,,,,2018,Aug.
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討","第34回日本DDS学会学術集会",,,,,,2018,June
"Nobuhiro Nishiyama","機能性ポリマーによるナノDDS設計：高分子ミセルからナノマシンへ","第34回日本DDS学会学術集会",,,,,,2018,June
"Ying Yao,Takahiro Nomoto,Yukiya Inoue,Minoru Suzuki,Makoto Matsui,Hiroyasu Takemoto,Keishiro Tomoda,Nobuhiro Nishiyama","Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy","第34回日本DDS学会学術集会",,,,,,2018,June
"Hiroyasu Takemoto,Ranneh Abdul-Hackam,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Yuki Mochida,Mitsuru Naito,Nobuhiro Nishiyama","腫瘍内環境を認識する高分子ベタインの開発とナノ粒子の効率的な腫瘍集積への展開","第67回高分子年次大会",,,,,,2018,May
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","siRNAへのCoil-globule挙動を有する高分子の結合と生体温度付近での遺伝子発現抑制能の精密制御","第67回高分子年次大会",,,,,,2018,May
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","可逆的にゲムシタビンを担持するポリアミノ酸型キャリアの開発とすい臓がんモデルでの機能評価","第67回高分子年次大会",,,,,,2018,May
"X. Dou,T. Nomoto,H. Takemoto,M. Matsui,K. Tomoda,N. Nishiyama","Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers",,"Scientific Reports",,"Vol. 8","No. 1","pp. 8126",2018,May
"A.-H. Ranneh,H. Takemoto,S. Sakuma,A. Awaad,T. Nomoto,Y. Mochida,M. Matsui,K. Tomoda,M. Naito,N. Nishiyama","An ethylenediamine-based switch to control the polyzwitterion charge at tumorous pH for effective tumor accumulation of coated nanomaterials",,"Angewandte Chemie International Edition",,"Vol. 57","No. 18","pp. 5057",2018,Apr.
"1.	野本貴大,Shigeto Fukushima,Michiaki Kumagai,Kozo Miyazaki,Aki Inoue,Peng Mi,Yoshinori Maeda,籐加珠子,Yu Mastumoto,Yuji Morimoto,Akihiro Kishimura,Nobuhiro Nishiyama,Kazunori Kataoka,Takahiro Nomoto","効率的な光線力学療法を指向したハイブリッド型光増感剤送達システム","日本薬学会 第138年会",,,,,,2018,Mar.
"Nobuhiro Nishiyama","Development of Smart Nanodiagnostics for Targeted Cancer Therapy","第2回MRIアライアンス国際シンポジウム2018",,,,,,2018,Jan.
"H. Takemoto,N. Nishiyama","Functional polymer-based siRNA delivery carrier that recognizes site- specific biosignals",,"Journal of Controlled Release",,"Vol. 267",,,2017,Dec.
"Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate","14th US-JAPAN Symposium on Drug Delivery Systems",,,,,,2017,Dec.
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Glutamine-Functionalized Polymer for Tumor-Selective High Affinity by Sensing Dense Glutamine Transporters Associated with Aberrant Metabolism","14th US-JAPAN Symposium on Drug Delivery Systems",,,,,,2017,Dec.
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん選択的に相互作用するグルタミン担持高分子の創製と機能評価","第39回日本バイオマテリアル学会大会",,,,,,2017,Nov.
"Hiroyasu Takemoto,Nobuhiro Nishiyama","Construction of siRNA-polymer conjugate and its biological application","IUMRS-ICA2017",,,,,,2017,Nov.
"Nobuhiro Nishiyama","Design of Functional Polymers for Smart Nanomedicine","International Symposium on Smart Biomaterials",,,,,,2017,Oct.
"Y. Anraku,H. Kuwahara,Y. Fukusato,A. Mizoguchi,T. Ishii,K. Nitta,Y. Matsumoto,K. Toh,K. Miyata,S. Uchida,K. Nishina,K. Osada,K. Itaka,N. Nishiyama,H. Mizusawa,T. Yamasoba,T. Yokota,K. Kataoka","Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain",,"Nature Communications",,"Vol. 8",,"pp. 1001",2017,Oct.
"M. Maeda,Y. Muragaki,J. Okamoto,S. Yoshizawa,N. Abe,H. Nakamoto,H. Ishii,K. Kawabata,S. Umemura,N. Nishiyama,K. Kataoka,H. Iseki","Sonodynamic therapy based on combined use of low dose administration of epirubicin-incorporating drug delivery system and focused ultrasound",,"Ultrasound Med. Biol.",,"Vol. 43","No. 10","pp. 2295-2301",2017,Oct.
"Shunya Sakuma,Abdul-Hackam RANNEH,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","腫瘍指向性ステルス高分子の開発とDDSへの応 用-ベタイン構造内アニオン性基の影響-","第66回高分子討論会",,,,,,2017,Sept.
"Hiroki Shinkai,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発","第66回高分子討論会",,,,,,2017,Sept.
"Xuebo Dou,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","光増感剤結合型高分子における多岐環状ＲＧＤペプチドの腫瘍集積性と腫瘍内分布への効果の検討","第66回高分子討論会",,,,,,2017,Sept.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減","第66回高分子討論会",,,,,,2017,Sept.
"Mi, Peng,Cabral, Horacio,Aoki, Ichio,Nobuhiro Nishiyama,Kataoka, Kazunori","A nanoparticle with pH-triggered contrast amplification ability for tumor malignancy imaging","4th Symposium on Innovative Polymers for Controlled Delivery (SIPCD)","JOURNAL OF CONTROLLED RELEASE","ELSEVIER SCIENCE BV","Vol. 259",,"pp. E102-E102",2017,Aug.
"Nobuhiro Nishiyama","革新的オリゴ核酸送達システムの実現に向けた材料設計","第33回日本DDS学会学術集会",,,,,,2017,July
"N. Yamada,Y. Honda,H. Takemoto,T. Nomoto,M. Matsui,K. Tomoda,M. Konno,H. Ishii,M. Mori,N. Nishiyama","Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism",,"Scientific Reports",,"Vol. 7","No. 1","pp. 6077",2017,July
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上","Photopolymer Science and Technology (ICPST-34)",,,,,,2017,July
"Hiroyasu Takemoto,Huang Chih-Hao,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-Nitrobenzenesulfonamide Group that Responds to Intracellular Redox Potential with Enhanced Photostability for a Construction of Polymer-siRNA Conjugate System","The 34th International Conference of Photopolymer Science and Technology (ICPST-34)",,,,,,2017,June
"Hiroki Shinkai,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発","第66回高分子年次大会",,,,,,2017,May
"P. Mi,H. Yanagie,N. Dewi,H.-C. Yen,X. Liu,M. Suzuki,Y. Sakurai,K. Ono,H. Takahashi,H. Cabral,K. Kataoka,N. Nishiyama","Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors",,"J. Control. Release",,"Vol. 254",,"pp. 1-9",2017,May
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発","第66回高分子年次大会",,,,,,2017,May
"Shunya Sakuma,Ranneh Hackam,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-","第66回高分子年次大会",,,,,,2017,May
"Hiroyasu Takemoto,Chih Hao Huang,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system","第66回高分子年次大会",,,,,,2017,May
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters","第66回高分子年次大会",,,,,,2017,May
"Hiroyasu Takemoto,Huang Chih-Hao,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate.","253rd American Chemical Society National Meeting & Exposition",,,,,,2017,Apr.
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism.","253rd American Chemical Society National Meeting & Exposition",,,,,,2017,Apr.
"H. Taniguchi,D. Hoshino,C. Moriya,H. Zembutsu,N. Nishiyama,H.  Yamamoto,K. Kataoka,K. Imai","Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer",,"Oncotarget",,"Vol. 8","No. 29","pp. 46856-46874",2017,Apr.
"Hiroyasu Takemoto,Hyun Jin Kim,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","単分子siRNA内包型小会合体を要素とするsiRNAキャリアの構築と全身投与による腫瘍組織への送達","日本薬学会第137年会",,,,,,2017,Mar.
"Ranneh Hackam,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of stealth shell based on polycarboxybetaine structure tuned to selectively interact with cells in tumor extracellular acidic pH","日本薬学会第137年会",,,,,,2017,Mar.
"Mitsuru Naito,Ryota Azuma,Hiroyasu Takemoto,Mao Hori,Naoto Yoshinaga,Shigehito Osawa,Rimpei Kamegawa,Hyun Jin Kim,Takehiko Ishii,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori","Multilayered Polyion Complexes with Dissolvable Silica Layer Covered by Controlling Densities of cRGD-conjugated PEG Chains for Cancer-targeted siRNA Delivery",,"Journal of Biomaterials Science, Polymer Edition",,"Vol. 28",,"pp. 1109-1123",2017,Mar.
"?Tsukasa Nishimori,Naoki Yamada,Hiroyasu Takemoto,Kentaro Suina,Juntaro Yamasaki,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Osamu Nagano,Hideyuki Saya,Nobuhiro Nishiyama","Development of intravenously injectable sulfasalazine derivatives to treat stem-like cancer cells","International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)",,,,,,2017,Mar.
"Takanori Inaba,Hiroyasu Takemoto,Makoto Matsui,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced antitumor activity and reduced gastrointestinal toxicity of gemcitabine based on conjugation with biocompatible polymer via acetal linker","International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)",,,,,,2017,Mar.
"Nobuhiro Nishiyama","革新的医薬品の実現に向けた機能性高分子およびナノデバイスの設計","帝人21世紀フォーラム",,,,,,2017,Feb.
"Nobuhiro Nishiyama","ペプチドリガンドを搭載したドラッグデリバリーシステム(DDS)の創製 (特集 生体機能性ペプチドを応用した次世代ナノメディシンの展開)",,"生化学","日本生化学会","Vol. 89","No. 1","pp. 39-43",2017,Feb.
"Nobuhiro Nishiyama","Development of smart polymers and nanodevices for innovative medicine","nternational Symposium on Materials for Chemistry and Engineering (IMCE2017)",,,,,,2017,Feb.
"Nobuhiro Nishiyama","Development of polymer-based nanodevices for innovative medicine","Snowbird Symposium for Dr. Kopecek",,,,,,2017,Feb.
"Nobuhiro Nishiyama","Development of smart nanomachines for cancer imaging and minimally invasive treatment","11th Annual Symposium on Nanobiotechnology 2017",,,,,,2017,Feb.
"Chi-Hao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group as a new chemical linker with redox sensitivity for siRNA-conjugated polymer system","11th Annual Symposium on Nanobiotechnology 2017",,,,,,2017,Feb.
"Chih-Hao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Utility of 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-conjugated Polymer System",,"ChemMedChem",,"Vol. 12","No. 1","pp. 19-22",2017,Jan.
"Nobuhiro Nishiyama","精密合成高分子材料を基盤とするナノメディシンの創製","第1回学院横断「物質科学」研究会",,,,,,2017,Jan.
"C. Moriya,H. Taniguchi,K. Miyata,N. Nishiyama,K. Kataoka,K. Imai","Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice",,"Carcinogenesis",,"Vol. 38","No. 6","pp. 638-648",2017,Jan.
"Nobuhiro Nishiyama","DDSによる核酸医薬の有効性向上・毒性低減に向けて","第2回革新的バイオ研究開発シンポジウム",,,,,,2017,Jan.
"Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Artificial control of siRNA bioactivity based on the phase transition behavior of the conjugated polymeric molecule","The 11th SPSJ International Polymer Conference (IPC2016)",,,,,,2016,Dec.
"Nobuhiro Nishiyama","evelopment of supramolecular nanodevices for cancer diagnostics and therapy","The Korean Academy of Science and Technology (KAST) Symposium for Young Scientists in Drug Delivery: Redirecting the Research Field",,,,,,2016,Dec.
"Chihhao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzensulfonamide groups as a chemical linker with enhanced extracellular stability and redox-sensitive cleavability for siRNA-conjugated polymer system","The 11th SPSJ International Polymer Conference (IPC2016)",,,,,,2016,Dec.
"越後真梨那,Hiroyasu Takemoto,Kotaro Hayashi,Kanjiro Miyata,金澤秀子,Kazunori Kataoka,Nobuhiro Nishiyama","がん細胞内にて特異的に切断される Linker を利用した siRNA 送達キャリアの開発","日本バイオマテリアル学会シンポジウム 2016",,,,,,2016,Nov.
"Nobuhiro Nishiyama","Challenge to new generation micellar nanocarriers","3rd International Conference on Biomaterials Science in Tokyo (ICBS2016)",,,,,,2016,Nov.
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel glutamine-based polymeric ligand for transporter-mediated tumor targeting","3rd International Conference on Biomaterials Science in Tokyo",,,,,,2016,Nov.
"Nobuhiro Nishiyama","精密合成高分子材料を基盤する がん診断・治療ナノマシンの創製","高分子同友会勉強会",,,,,,2016,Nov.
"Hiroyasu Takemoto,Kanjiro Miyata,Kotaro Hayashi,Yuki Mochida,Kazunori Kataoka,Nobuhiro Nishiyama","シロキサンネットワークにて形成されるsiRNA内包有機-無機ハイブリッドナノ粒子の開発","日本バイオマテリアル学会シンポジウム 2016",,,,,,2016,Nov.
"P. Mi,F. Wang,N. Nishiyama,H. Cabral","Molecular cancer imaging with polymeric nanoassemblies: from tumor detection to theranostics",,,,,,,2016,Oct.
"Nobuhiro Nishiyama","高分子ナノテクノロジーを基盤とした革新的ナノ診断・治療システムの開発","日本薬物動態学会 第31回年会",,,,,,2016,Oct.
"Nobuhiro Nishiyama","精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製","科研費新学術領域「分子ロボティクス」公開シンポジウム",,,,,,2016,Oct.
"Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Development of siRNA-conjugated polymer with coil-globule transition behavior for an artificially controlled gene silencing activity","第65回高分子討論会",,,,,,2016,Sept.
"Chih Ling Wang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","A Novel Design of Polyion Complex (PIC) with The Pyruvate-Reactive Function toward Enhanced Cytosolic Release of siRNA","第65回高分子討論会",,,,,,2016,Sept.
"Junhyun Kim,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","高分子ミセルにおける内核構造の安定性の差異がもたらす腫瘍集積性に関する考察","第65回高分子討論会",,,,,,2016,Sept.
"Xiaohang Sun,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","がんへの薬剤の集積状態をレポートするナノメディシンの開 発","第65回高分子討論会",,,,,,2016,Sept.
"Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil?Globule Transition Behavior",,"Bioconjugate Chemistry",,,,,2016,Aug.
"Nobuhiro Nishiyama","高分子ミセル型ナノ医薬品の開発-アカデミアからの取り組み-","第32回日本DDS学会学術大会",,,,,,2016,July
"Nobuhiro Nishiyama","高分子ナノテクノロジーを基盤とした革新的DDSの開発","次世代バイオ医薬品・再生医療を支える基盤技術開発",,,,,,2016,July
"Nobuhiro Nishiyama","がんの標的治療のための高分子ミセル型薬物送達システムの開発","新製剤技術とエンジニアリングを考える会 第14回技術講演会",,,,,,2016,July
"Nobuhiro Nishiyama","高分子ナノテクノロジーを基盤とする革新的がん診断・治療システムの創出","第51回天然物化学談話会",,,,,,2016,July
"H. Hino,M. Kamiya,K. Kitano,K. Mizuno,S. Tanaka,N. Nishiyama,K. Kataoka,Y. Urano,J. Nakajima","Rapid cancer fluorescence imaging using a γ-glutamyltranspeptidase-specific probe for primary lung cancer",,"Translational Oncology",,"Vol. 9","No. 3","pp. 203-210",2016,June
"M. Iijima,D. Ulkoski,S. Sakuma,D. Matsukuma,N. Nishiyama,H. Otsuka,C. Scholz","Synthesis of PEGylated poly(amino acid) pentablock copolymers and their self-assembly",,"Polymer International",,"Vol. 65","No. 10","pp. 1132-1141",2016,June
"Nobuhiro Nishiyama,Yasuhiro Matsumura,Kazunori Kataoka","Development of polymeric micelles for targeting intractable cancers.",,"Cancer science",,"Vol. 107","No. 7","pp. 867-74",2016,June
"Chih-Ling,Hiroyasu Takemoto,Nobuhiro Nishiyama","Programmed siRNA Release based on α-Oxohydrazone Chemistry for Polyion complex-based siRNA Delivery System","第６５回高分子学会年次大会",,,,,,2016,May
"Peng Mi,Daisuke Kokuryo,Cabral Horacio,Hailiang Wu,Yasuko Terada,Tsuneo Saga,Ichio Aoki,Nobuhiro Nishiyama,Kazunori Kataoka","A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy",,"Nature Nanotechnology",,"Vol. 11","No. 8","pp. 724-+",2016,May
"Nobuhiro Nishiyama","高分子ミセル型ナノマシンが拓く未来医療","第63回日本実験動物学会総会",,,,,,2016,May
"Nobuhiro Nishiyama","高分子ナノテクノロジーを基盤とする革新的ナノメディシンの創製","先端化学・材料技術 高選択性反応分科会 講演会",,,,,,2016,May
"NOOR,Hiroyasu Takemoto,Takahiro Nomoto,Nobuhiro Nishiyama","Development of thermoresponsive polymer-siRNA conjugates for controlled RNAi activity","第６５回高分子学会年次大会",,,,,,2016,May
"Yoko Matsumoto,Miyamoto Yuichiro,Cabral Horacio,Yu Mastumoto,Kazunori Nagasawa,Shunsuke Nakagawa,Tetsu Yano,Daichi Maeda,Katsutoshi Oda,Kei Kawana,Nobuhiro Nishiyama,Kazunori Kataoka,Tomoyuki Fujii","Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132",,"Cancer Science",,"Vol. 107","No. 6","pp. 773-781",2016,Apr.
"Haruka Nishida,Yoko Matsumoto,Kei Kawana,Christie James,Mitsuru Naito,Kim Beob Soo,Kazuko Toh,Hyun Su Min,Yi Yu,Yu Mastumoto,Hyun Jin Kim,Kanjiro Miyata,Ayumi Taguchi,Kensuke Tomio,Aki Yamashita,Tomoko Inoue,Hiroe Nakamura,Asaha Fujimoto,Masakazu Sato,Mitsuyo Yoshida,Katsuyuki Adachi,Takahide Arimoto,Osamu Wada-Hiraike,Katsutoshi Oda,Takeshi Nagamatsu,Nobuhiro Nishiyama,Kazunori Kataoka,Yutaka Osuga,Tomoyuki Fujii","Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes",,"Journal of Controlled Release",,"Vol. 231",,"pp. 29-37",2016,Mar.
"Takahiro Nomoto,Shigeto Fukushima,Michiaki Kumagai,Kozo Miyazaki,Aki Inoue,Peng Mi,Yoshinori Maeda,Kazuko Toh,Yu Mastumoto,Yuji Morimoto,Akihiro Kishimura,Nobuhiro Nishiyama,Kazunori Kataoka","Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy.",,"Biomaterials science",,"Vol. 4","No. 5","pp. 826-838",2016,Mar.
"Nobuhiro Nishiyama","Development of supramolecular nanodevices for cancer diagnosis and therapy","Joint Workshop between Nanyang Technological University (NTU) and Tokyo Institute of Technology (Tokyo Tech)",,,,,,2016,Feb.
"Nobuhiro Nishiyama","高分子ナノテクノロジーを基盤とした革新的核酸医薬シーズ送達システムの創出","第1回革新的バイオ研究開発シンポジウム",,,,,,2016,Jan.
"Nobuhiro Nishiyama","Development of supramolecular nanodevices for cancer diagnosis and therapy","The 4th International Bioscience and Biotechnology Symposium on Multifaceted Approaches to Disease Intervention",,,,,,2016,Jan.
"Nobuhiro Nishiyama,Horacio Cabral","Development of supramolecular nanomedicines for cancer diagnosis and therapy","The e-Asia Joint Research Program Workshop on “Green and Bio Nanotechnology for Innovative Materials System”",,,,,,2016,Jan.
"Hirokuni Uchida,Keiji Itaka,Satoshi Uchida,Takehiko Ishii,Tomoya Suma,Kanjiro Miyata,Makoto Oba,Nobuhiro Nishiyama,Kazunori Kataoka","Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure",,"Journal of the American Chemical Society",,"Vol. 138","No. 5","pp. 1478-1481",2016,Jan.
"Kotaro Hayashi,Hiroyuki Chaya,Shigeto Fukushima,Sumiyo Watanabe,Hiroyasu Takemoto,Kensuke Osada,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers",,"Macromolecular Rapid Communications",,"Vol. 37","No. 6","pp. 486-493",2016,Jan.
"Kotaro Hayashi,Hiroyuki Chaya,Shigeto Fukushima,Sumiyo Watanabe,Hiroyasu Takemoto,Kensuke Osada,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Macromol. Rapid Commun. 6/2016.",,"Macromolecular rapid communications",,"Vol. 37","No. 6","pp. 560",2016,Jan.
"Novriana Dewi,Peng Mi,Hironobu Yanagie,Yuriko Sakurai,Yasuyuki Morishita,Masashi Yanagawa,Takayuki Nakagawa,Atsuko Shinohara,Takehisa Mastukawa,Kazuhito Yokoyama,Cabral Horacio,Minoru Suzuki,Yoshinori Sakurai,Hiroki Tanaka,Koji Ono,Nobuhiro Nishiyama,Kazunori Kataoka,Hiroyuki Takahashi","In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent",,"Journal of Cancer Research and Clinical Oncology",,"Vol. 142","No. 4","pp. 767-775",2015,Dec.
"Takahiro Nomoto,Shigeto Fukushima,Michiaki Kumagai,Kaori Machitani,Kanjiro Miyata,Makoto Oba,Yu Matsumoto,Kensuke Osada,Nobuhiro Nishiyama,Kazunori Kataoka","Three-layered polyplex micelle for light-induced gene transfer","The 13th US-Japan DDS symposium",,,,,,2015,Dec.
"Masahiro Murakami,Kazutaka Nishina,Chie Watanabe,Kie Yoshida-Tanaka,Wenying Piao,Hiroya Kuwahara,Yuji Horikiri,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka,Masayuki Yoshida,Hidehiro Mizusawa,Takanori Yokota","Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route",,"Scientific Reports",,"Vol. 5",,,2015,Nov.
"Hino, Haruaki,Kawashima, Mitsuaki,Murayama, Tomonori,Ichinose, Junji,Kitano, Kentaro,Nagayama, Kazuhiro,Nitadori, Jun-ichi,Anraku, Masaki,Murakawa, Tomohiro,Mizuno, Kasue,Tanaka, Sayaka,Kamiya, Mako,Nobuhiro Nishiyama,Kataoka, Kazunori,Miyazono, Kohei,Urano, Yasuteru,Nakajima, Jun","Rapid Cancer Imaging By GGT-targeted Fluorescence Probe For Primary Lung Cancer","106th Annual Meeting of the American-Association-for-Cancer-Research (AACR)","CANCER RESEARCH","AMER ASSOC CANCER RESEARCH","Vol. 75",,,2015,Aug.
"Kumiko Sakai-Kato,Nobuhiro Nishiyama,Masato Kozaki,Takeshi Nakanishi,Yoshihiro Matsuda,Mai Hirano,Hiroyuki Hanada,Shigeru HIsada,Hiroshi Onodera,Hideyoshi Harashima,Yasuhiro Matsumura,Kazunori Kataoka,Yukihiro Goda,Haruhiko Okuda,Toru Kawanishi","General considerations regarding the in vitro and in vivo properties of block copolymer micelle products and their evaluation",,"Journal of Controlled Release",,"Vol. 210",,"pp. 76-83",2015,July
"Kumiko Sakai-Kato,Kunie Nanjo,Hiroyuki Kusuhara,Nobuhiro Nishiyama,Kazunori Kataoka,Toru Kawanishi,Haruhiko Okuda,Yukihiro Goda","Effect of Knockout of Mdr1a and Mdr1b ABCB1 Genes on the Systemic Exposure of a Doxorubicin-Conjugated Block Copolymer in Mice",,"Molecular Pharmaceutics",,"Vol. 12","No. 9","pp. 3175-3183",2015,July
"Peng Mi,Novriana Dewi,Hironobu Yanagie,Daisuke Kokuryo,Minoru Suzuki,Yoshinori Sakurai,Yanmin Li,Ichio Aoki,Koji Ono,Hiroyuki Takahashi,Cabral Horacio,Nobuhiro Nishiyama,Kazunori Kataoka","Hybrid Calcium Phosphate-Polymeric Micelles Incorporating Gadolinium Chelates for Imaging-Guided Gadolinium Neutron Capture Tumor Therapy",,"Acs Nano",,"Vol. 9","No. 6","pp. 5913-5921",2015,June
"Peng Mi,Hironobu Yanagie,Daisuke Kokuryo,Novriana Dewi,Ichio Aoki,Nobuhiro Nishiyama,Kazunori Kataoka","Block copolymer hybrid calcium phosphate micelles for cancer diagnosis and neutron capture therapy",,"Journal of Controlled Release",,"Vol. 213",,"pp. E88",2015,May
"Nobuhiro Nishiyama","[FOREWORD]アカデミアと企業の連携による医療イノベーションの実現に向けて",,"Drug Delivery System","日本DDS学会","Vol. 30","No. 3","pp. 179-179",2015,
"Hiroyasu Takemoto,Nobuhiro Nishiyama","ジブロックコポリマーを基盤とする高分子ミセル型制がん剤送達キャリア",,"DDSキャリア作成プロトコル集",,,,"  73-79",2015,
"Ogawa, H.,Wu, X.,Kawamoto, K.,Nishida, N.,Konno, M.,Koseki, J.,Matsui, H.,Noguchi, K.,Gotoh, N.,Yamamoto, T.,Miyata, K.,Nobuhiro Nishiyama,Nagano, H.,Yamamoto, H.,Obika, S.,Kataoka, K.,Doki, Y.,Mori, M.,Ishii, H.","MicroRNAs induce epigenetic reprogramming and suppress malignant phenotypes of human colon cancer cells",,"PLoS ONE",,"Vol. 10","No. 5",,2015,
"K. Miura,T. Hirasawa,J. Kang,Y. Shoji,Y. Okada,H. Yokoi,N. Nishiyama,S. Arai,Tetsuya Mizumoto","Amorphous Silicon Waveguide Optical Isolator on Ce:YIG Substrate","The 4th International Symposium on Photonics and Electronics Convergence",,,,,,2014,Nov.
"Osada, Kensuke,Cabral, Horacio,Mochida, Yuki,Anraku, Yasutaka,Kishimura, Akihiro,Nobuhiro Nishiyama,Kataoka, Kazunori","Metallosomes as bioactive polymersomes formed by supramolecular assembly of block copolymer-metal complexation","248th National Meeting of the American-Chemical-Society (ACS)","ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY","AMER CHEMICAL SOC","Vol. 248",,,2014,Aug.
"Yoshinori Maeda,Frederico Pittella,Takahiro Nomoto,Hiroyasu Takemoto,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles",,"Macromolecular Rapid Communications",,"Vol. 35","No. 13","pp. 1211-1215",2014,
"Frederico Pittella,Cabral Horacio,Yoshinori Maeda,Peng Mi,Sumiyo Watanabe,Hiroyasu Takemoto,Hyun Jin Kim,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles",,"Journal of Controlled Release",,"Vol. 178",,"pp. 18-24",2014,
"Hyun Jin Kim,Hiroyasu Takemoto,Yi Yu,Meng Zheng,Yoshinori Maeda,Hiroyuki Chaya,Kotaro Hayashi,Peng Mi,Frederico Pittella,Christie James,Kazuko Toh,Yu Mastumoto,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles",,"Acs Nano",,"Vol. 8","No. 9","pp. 8979-8991",2014,
"Nobuhiro Nishiyama,Hiroyasu Takemoto","Polymeric Micelles",,"Encyclopedia of Polymeric Nanomaterials",,,,,2014,
"Hiroyasu Takemoto,Nobuhiro Nishiyama","Design of Functional Polymers for Intracellular Nucleic Acids Delivery",,"Intracellular Delivery Ii: Fundamentals and Applications",,"Vol. 7",,"pp. 207-217",2014,