"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of poly(amino acid)-based carrier that loads gemcitabine via reversible linkage and its evaluation using pancreatic cancer model","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Yuka Kaihara,Makoto Matsui,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Development of novel drug delivery system for enhancing bone regeneration in bone fracture model mouse","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Yuto Honda,Naoki Yamada,Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism.","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "西山 伸宏","機能性高分子の精密設計に基づくナノメディシンの創製","日本接着学会東北支部講演会2018",,,,,,2018,Dec. "Sun Xiaohang,Taknaori Inaba,Kazuki Ohsakama,Mika Shishido,Hiroki Yoshioka,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","Development of degradable poly(ethylene glycol)(PEG) derivatives for suppressing cellular vacuolations","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Conjugation of siRNA and a polymer with coil-globule transition property for control of siRNA activity around body temperature","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety",,"BIOMACROMOLECULES",,"Vol. 20","No. 4","pp. 1493-1504",2018,Dec. "Tsukasa Chida,Yutaka Miura,Cabral Horacio,Takahiro Nomoto,Kazunori Kataoka,Nobuhiro Nishiyama","Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release",,"J. Control. Release",,"Vol. 292",,"pp. 130-140",2018,Dec. "Hiroyasu Takemoto,Abdul-Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","Ethylenediamine-based polyzwitterion that becomes cationic at tumorous pH for effective tumor accumulation of the coated nanomaterials","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Sjaikhurrizal El Muttaqien,松井 誠,武元 宏泰,野本 貴 大,友田 敬士郎,西山 伸宏","Poly(N-isopropylacrylamide) derivatives exering remarkable LCST shift in response to slight pH chnge via detachment of hydrophilic acid-labile moiety","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Nobuhiro Nishiyama","Smart nanomedicines based on the design of functional polymer","International Conference on Emerging Healthcare Materials 2018 (ICEHM2018)",,,,,,2018,Nov. "西山 伸宏","機能性高分子の設計に基づくがん診断・治療システムの開発","第35回医用高分子研究会講座",,,,,,2018,Nov. "Ying Yao,Takahiro Nomoto,Yukiya Inoue,Minoru Suzuki,Makoto Matsui,Hiroyasu Takemoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced tumor-targeted delivery of p-boronophenylalanine using fructose-functionalized polymers for boron neutron capture therapy","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct. "西山 伸宏","機能性ポリマーの精密設計に基づく スマート機能型ナノメディシンの創製","第56回日本癌治療学会学術集会",,,,,,2018,Oct. "Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Metabolism-controlled boron delivery systems composed of p-boronophenylalanine and poly(vinyl alcohol)","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct. "Takahiro Nomoto,Nobuhiro Nishiyama","Design of drug delivery systems for physical energy-induced chemical surgery",,"Biomaterials","Elsevier","Volume 178",,"pp. 583-596",2018,Sept. "Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Multiple cyclic RGD-conjugated functional polymers controlling intratumoral distribution of IRDye 700DX","Photodynamic Therapy and Photodiagnosis Update 2018",,,,,,2018,Sept. "Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","Size-regulated siRNA carriers from small complex loading single siRNA molecule for systemic delivery to tumor tissue","第77回日本癌学会学術総会",,,,,,2018,Sept. "Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of gemcitabine-conjugated poly(amino acid) and its evaluation using pancreatic tumor model","第67回高分子討論会",,,,,,2018,Sept. "本田雄士,山田 直生,武元 宏泰,野本 貴 大,松井 誠,友田 敬士郎,西山 伸宏","グルタミン代謝が亢進したがん細胞の高密度グルタ ミントランスポーターを認識してアフィニティを示す機能性高 分子","第67回高分子討論会",,,,,,2018,Sept. "野本 貴大,井上 透矢,Yao Ying,鈴木 実,金盛 開人,武元 宏泰,松井 誠,友田 敬士郎,西山 伸宏","生体適合性機能性高分子によるボロノフェニルアラニンの代謝制御と治療効果の向上","第15回日本中性子捕捉療法学会学術大会",,,,,,2018,Sept. "Hiroyasu Takemoto,Abduhl Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials","256th ACS National Meeting & Exposition",,,,,,2018,Aug. "Sjaikhurrizal El Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor","256th ACS National Meeting & Exposition",,,,,,2018,Aug. "R. Toshiyama R,M. Konno,H. Eguchi,H. Takemoto,T. Noda,A. Asai,J. Koseki,N. Haraguchi,Y. Ueda,K. Matsushita,K. Asukai,T. Ohashi,Y. Iwagami,D. Yamada,D. Sakai,T. Asaoka,T. Kudo,K. Kawamoto,K. Gotoh,S. Kobayashi,T. Satoh,Y. Doki,N. Nishiyama,M. Mori,H. Ishii","Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells",,"Oncogene",,"Vol. 38","No. 2","pp. 244-260",2018,Aug. "西山伸宏","機能性ポリマーによるナノDDS設計:高分子ミセルからナノマシンへ","第34回日本DDS学会学術集会",,,,,,2018,June "野本貴大,Dou Xuebo,武元宏泰,松井誠,友田敬士郎,西山伸宏","IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討","第34回日本DDS学会学術集会",,,,,,2018,June "yao ying,野本貴大,井上透矢,鈴木実,松井誠,武元宏泰,友田敬士郎,西山伸宏","Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy","第34回日本DDS学会学術集会",,,,,,2018,June "X. Dou,T. Nomoto,H. Takemoto,M. Matsui,K. Tomoda,N. Nishiyama","Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers",,"Scientific Reports",,"Vol. 8","No. 1","pp. 8126",2018,May "小野寺彩,武元宏泰,野本貴大,友田敬士郎,松井誠,西山伸宏","siRNAへのCoil-globule挙動を有する高分子の結合と生体温度付近での遺伝子発現抑制能の精密制御","第67回高分子年次大会",,,,,,2018,May "劉暁夢,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","可逆的にゲムシタビンを担持するポリアミノ酸型キャリアの開発とすい臓がんモデルでの機能評価","第67回高分子年次大会",,,,,,2018,May "武元宏泰,Ranneh Abdul-Hackam,野本貴大,松井誠,友田敬士郎,持田祐希,内藤瑞,西山伸宏","腫瘍内環境を認識する高分子ベタインの開発とナノ粒子の効率的な腫瘍集積への展開","第67回高分子年次大会",,,,,,2018,May "A.-H. Ranneh,H. Takemoto,S. Sakuma,A. Awaad,T. Nomoto,Y. Mochida,M. Matsui,K. Tomoda,M. Naito,N. Nishiyama","An ethylenediamine-based switch to control the polyzwitterion charge at tumorous pH for effective tumor accumulation of coated nanomaterials",,"Angewandte Chemie International Edition",,"Vol. 57","No. 18","pp. 5057",2018,Apr. "1. 野本貴大,福島重人,熊谷康顕,宮崎幸造,井上明季,Mi Peng,前田芳周,籐加珠子,松本有,守本祐司,岸村顕広,西山伸宏,片岡一則,野本貴大","効率的な光線力学療法を指向したハイブリッド型光増感剤送達システム","日本薬学会 第138年会",,,,,,2018,Mar. "Nobuhiro Nishiyama","Development of Smart Nanodiagnostics for Targeted Cancer Therapy","第2回MRIアライアンス国際シンポジウム2018",,,,,,2018,Jan.