@book{CTT100836328,
author = {Fumitaka Kudo},
title = {Biosynthesis of Aminoglycoside Antibiotics},
publisher = {Elsevier},
year = 2020,
}
@book{CTT100571356,
author = {市村 禎二郎 and 藤本 善徳 and 小松 隆之 and 鈴木 正 and 原 典行 and 松下 慶寿 and 小澤 健一 and 工藤 史貴 and 高井 和之 and 水上 真由美 and 追中 寛 and 岩井 敦子},
title = {理工系大学 基礎化学実験 第3版},
publisher = {講談社サイエンティフィク},
year = 2008,
}
@article{CTT100920632,
author = {Fumitaka Kudo and Kazuma Tsuboi and Mutsumi Ikezaki and Daiki Nagayama and Koichi Kawamura and Taishi Ando and Akimasa Miyanaga and Tadashi Eguchi},
title = {The Post-Polyketide Synthase Modification Mechanism in Hitachimycin Biosynthesis},
journal = {ChemBioChem},
year = 2024,
}
@article{CTT100920633,
author = {Fumitaka Kudo},
title = {Biosynthesis of macrolactam antibiotics with β-amino acid polyketide starter units},
journal = {J. Antibiot.},
year = 2024,
}
@article{CTT100920631,
author = {Dawei Wang and Akimasa Miyanaga and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi},
title = {Engineering the Substrate Specificity of (S)-β-Phenylalanine Adenylation Enzyme HitB},
journal = {ChemBioChem},
year = 2024,
}
@article{CTT100920630,
author = {Akimasa Miyanaga and Kenji Nagata and Joji Nakajima and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi},
title = {Structural Basis of Amide-Forming Adenylation Enzyme VinM in Vicenistatin Biosynthesis},
journal = {ACS Chem. Biol.},
year = 2023,
}
@article{CTT100895298,
author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Cross-Linking of the Nonribosomal Peptide Synthetase Adenylation Domain with a Carrier Protein Using a Pantetheine-Type Probe},
journal = {Non-Ribosomal Peptide Biosynthesis and Engineering: Methods and Protocols},
year = 2023,
}
@article{CTT100920628,
author = {Taichi Chisuga and satoshi murakami and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase},
journal = {ACS Chem. Biol.},
year = 2023,
}
@article{CTT100895296,
author = {Fumitaka Kudo and Takuji Chikuma and Mizuki Nambu and Taichi Chisuga and Shimpei Sumimoto and Arihiro Iwasaki and Kiyotake Suenaga and Akimasa Miyanaga and Tadashi Eguchi},
title = {Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii},
journal = {ACS Chem. Biol.},
year = 2023,
}
@article{CTT100887107,
author = {Fumitaka Kudo and Kosuke Kishikawa and Kazuma Tsuboi and Takafusa Kido and Takeo Usui and Junko Hashimoto and Kazuo Shin-ya and Akimasa Miyanaga and Tadashi Eguchi},
title = {Acyltransferase Domain Exchanges between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics},
journal = {ChemBioChem},
year = 2023,
}
@article{CTT100884597,
author = {Akimasa Miyanaga and Koichi Kawada and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi},
title = {Structural Basis of Transient Interactions of the Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase},
journal = {BIOCHEMISTRY},
year = 2023,
}
@article{CTT100882107,
author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Recent Advances in Structural Analysis of Adenylation Domain in Natural Product Biosynthesis},
journal = {Curr. Opin. Chem. Biol.},
year = 2022,
}
@article{CTT100884397,
author = {Fumitaka Kudo and Atsushi Minato and Shusuke Sato and Nayuta Nagano and Chitose Maruyama and Yoshimitsu Hamano and Junko Hashimoto and Ikuko Kozone and Kazuo Shin-ya and Tadashi Eguchi},
title = {Mechanism of S-Adenosyl-L-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-L-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis},
journal = {ORG LETT},
year = 2022,
}
@article{CTT100881283,
author = {Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthesis of Cyclitols},
journal = {Nat. Prod. Rep},
year = 2022,
}
@article{CTT100869840,
author = {Shusuke Sato and Fumitaka Kudo and Tadashi Eguchi},
title = {Characterization of the Cobalamin-Dependent Radical SAM C-Methyltransferase Fom3 in Fosfomycin Biosynthesis},
journal = {Methods Enymol.},
year = 2022,
}
@article{CTT100865326,
author = {Taichi Chisuga and Akira Nagai and Akimasa Miyanaga and Ena Goto and Kosuke Kishikawa and Fumitaka Kudo and Tadashi Eguchi},
title = {Structural Insight into the Reaction Mechanism of Ketosynthase-Like Decarboxylase in a Loading Module of Modular Polyketide Synthases},
journal = {ACS Chem. Biol.},
year = 2022,
}
@article{CTT100861310,
author = {Akimasa Miyanaga and Risako Ouchi and Fumitaka Kudo and Tadashi Eguchi},
title = {Complex Structure of the Acyltransferase VinK and the Carrier Protein VinL with a Pantetheine Cross-linking Probe},
journal = {Acta Crystallogr F Struct. Biol. Commun.},
year = 2021,
}
@article{CTT100861907,
author = {Shusuke Sato and Fumitaka Kudo and Michel Rohmer and Tadashi Eguchi},
title = {Biochemical and Mutational Analysis of Radical SAM Adenosylhopane Synthase HpnH Derived from Zymomonas mobilis Reveals that the Conserved Cysteine-106 Residue Reduces a Radical Intermediate and Determines the Stereochemistry},
journal = {Biochemistry},
year = 2021,
}
@article{CTT100847581,
author = {Fumitaka Kudo and Yukinobu Kitayama and Akimasa Miyanaga and Mario Numakura and Tadashi Eguchi},
title = {Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis},
journal = {ChemBioChem},
year = 2021,
}
@article{CTT100845120,
author = {Fumitaka Kudo and Sotaro Takahashi and Akimasa Miyanaga and Yuichiro Nakazawa and Kota Nishino and Yuki Hayakawa and Koichi Kawamura and Fumihiro Ishikawa and Naeko Iwai and Yoko Nagumo and Takeo Usui and Tadashi Eguchi},
title = {Mutational Biosynthesis of the Hitachimycin Analogs Regulated by β-Phenylalanine Selective Adenylation Enzyme HitB},
journal = {ACS Chemical Biology},
year = 2021,
}
@article{CTT100842144,
author = {Fumitaka Kudo and Ayaka Mori and Mai Koide and Ryo Yajima and Ryohei Takeishi and Akimasa Miyanaga and Tadashi Eguchi},
title = {One-pot Enzymatic Synthesis of 2-Deoxy-scyllo-inosose from D-Glucose and Polyphosphate},
journal = {Biosci. Biotechnol. Biochem.},
year = 2021,
}
@article{CTT100833477,
author = {Akimasa Miyanaga and Ryoma Takaku and Makoto Takaishi and Etsu Tashiro and Fumitaka Kudo and Tadashi Eguchi},
title = {Generation of Incednine Derivatives by Mutasynthesis},
journal = {J. Antibiot.},
year = 2020,
}
@article{CTT100829288,
author = {Akimasa Miyanaga and Shohei Kurihara and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi},
title = {Structural Characterization of Complex of Adenylation Domain and Carrier Protein by using Pantetheine Cross-linking Probe},
journal = {ACS Chem. Biol.},
year = 2020,
}
@article{CTT100823503,
author = {Chitose Maruyama and Yukiko Chinone and Shusuke Sato and Fumitaka Kudo and Kosuke Ohsawa and Junya Kubota and Junko Hashimoto and Ikuko Kozone and Takayuki Doi and Kazuo Shin-ya and Tadashi Eguchi and Yoshimitsu Hamano},
title = {C-Methylation of S-Adenosyl-L-methionine Occurs prior to Cyclopropanation in the Biosynthesis of a Bacterial 1-Amino-2-methylcyclopropanecarboxylic Acid (Norcoronamic acid) in a Bacterium},
journal = {Biomolecules},
year = 2020,
}
@article{CTT100820078,
author = {工藤史貴 and 江口正},
title = {生体内におけるラジカル反応：ラジカル酵素による炭素–炭素結合形成反応},
journal = {化学},
year = 2020,
}
@article{CTT100821998,
author = {Fumitaka Kudo and Yukinobu Kitayama and Akimasa Miyanaga and Akane Hirayama and Tadashi Eguchi},
title = {Biochemical and Structural Analysis of a Dehydrogenase KanD2 and an Aminotransferase KanS2 that are Responsible for the Construction of the Kanosamine Moiety in Kanamycin Biosynthesis},
journal = {Biochemistry},
year = 2020,
}
@article{CTT100811958,
author = {Shusuke Sato and Fumitaka Kudo and Michel Rohmer and Tadashi Eguchi},
title = {Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5’-Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C35 Bacteriohopanepolyols},
journal = {Angew. Chem. Int. Ed.},
year = 2020,
}
@article{CTT100809797,
author = {Daisuke Kawasaki and Akimasa Miyanaga and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi},
title = {Functional and Structural Analyses of Split-Dehydratase Domain in the Biosynthesis of Macrolactam Polyketide Cremimycin},
journal = {Biochemistry},
year = 2019,
}
@article{CTT100813105,
author = {Fumitaka Kudo and Takeshi Tsunoda and Kaito Yamaguchi and Akimasa Miyanaga and Tadashi Eguchi},
title = {Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis},
journal = {Biochemistry},
year = 2019,
}
@article{CTT100806649,
author = {Fumitaka Kudo and Jiahao Zhang and Shusuke Sato and Akane Hirayama and Tadashi Eguchi},
title = {Functional Characterization of 3-Aminobenzoic Acid Adenylation Enzyme PctU and UDP-N-Acetyl-D-Glucosamine: 3-Aminobenzoyl-ACP Glycosyltransferase PctL in Pactamycin Biosynthesis},
journal = {ChemBioChem},
year = 2019,
}
@article{CTT100804280,
author = {佐藤秀亮 and 工藤史貴 and 江口正},
title = {抗生物質ホスホマイシン生合成の全貌解明},
journal = {バイオサイエンスとインダストリー},
year = 2019,
}
@article{CTT100799606,
author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Structural Analysis of Glycine Oxidase Homologue CmiS2 Reveals a Unique Substrate Recognition Mechanism for Formation of a β-Amino Acid Starter Unit in Cremimycin Biosynthesis},
journal = {BIOCHEMISTRY},
year = 2019,
}
@article{CTT100795800,
author = {Fumihiro Ishikawa and Akimasa Miyanaga and Hinano Kitayama and Shinya Nakamura and Isao Nakanishi and Fumitaka Kudo and Tadashi Eguchi and Genzoh Tanabe},
title = {An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket},
journal = {Angew. Chem. Int. Ed.},
year = 2019,
}
@article{CTT100798092,
author = {Xiaoli Zhang and Wei Chen and Qiong Gao and Junsheng Yang and Xueni Yan and Han Zhao and Lin Su and Meimei Yang and Chenlang Gao and Yao Yao and Ken Inoki and Dan Li and Rong Shao and Shiyi Wang and Nirakar Sahoo and Fumitaka Kudo and Tadashi Eguchi and Benfang Ruan and Haoxing Xu},
title = {Rapamycin Directly Activates Lysosomal Mucolipin TRP Channels Independent of mTOR},
journal = {PLOS Biol.},
year = 2019,
}
@article{CTT100793478,
author = {Jolanta Cieślak and Akimasa Miyanaga and Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi},
title = {Functional and Structural Characterization of Adenylation Enzyme IdnL7 Involved in Incednine Biosynthesis},
journal = {Acta Crystallogr. F Struct. Biol. Commun.},
year = 2019,
}
@article{CTT100790301,
author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi},
title = {Structural Basis of Nonribosomal Codes for Nonproteinogenic Amino Acid Selective Adenylation Enzymes in the Biosynthesis of Natural Products},
journal = {J. Ind. Microbiol. Biotechnol.},
year = 2019,
}
@article{CTT100818968,
author = {M. Ninomiya and Yoshio Ando and Fumitaka Kudo and K. Ohmori and KEISUKE SUZUKI},
title = {Total Synthesis of Actinorhodin},
journal = {Angewandte Chemie-International Edition},
year = 2019,
}
@article{CTT100777252,
author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Protein-Protein Interactions in Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Assembly Lines},
journal = {Nat. Prod. Rep.},
year = 2018,
}
@article{CTT100770338,
author = {Shusuke Sato and Akimasa Miyanaga and Seung-Young Kim and Tomohisa Kuzuyama and Fumitaka Kudo and Tadashi Eguchi},
title = {Biochemical and Structural Analysis of FomD that Catalyzes the Hydrolysis of Cytidylyl (S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis},
journal = {BIOCHEMISTRY},
year = 2018,
}
@article{CTT100770362,
author = {Shusuke Sato and Fumitaka Kudo and Tomohisa Kuzuyama and Friedrich Hammerschmidt and Tadashi Eguchi},
title = {C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-Adenosyl-L-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration},
journal = {BIOCHEMISTRY},
year = 2018,
}
@article{CTT100769097,
author = {Akimasa Miyanaga and Risako Ouchi and Fumihiro Ishikawa and Ena Goto and Genzoh Tanabe and Fumitaka Kudo and Tadashi Eguchi},
title = {Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis},
journal = {J. Am. Chem. Soc.},
year = 2018,
}
@article{CTT100758696,
author = {Satoru Watanabe and Hiroaki Ozawa and Hiroaki Kato and Kaori Nimura-Matsune and Toshifumi Hirayama and Fumitaka Kudo and Tadashi Eguchi and Katsumi Kakinuma and Hirofumi Yoshikawa},
title = {Carbon-free Production of 2-Deoxy-scyllo-inosose (DOI) in Cyanobacterium Synechococcus elongatus PCC 7942},
journal = {Biosci. Biotechnol. Biochem.},
year = 2018,
}
@article{CTT100758522,
author = {Akane Hirayama and Jinmiao Chu and Ena Goto and Fumitaka Kudo and Tadashi Eguchi},
title = {NAD(+)-Dependent Dehydrogenase PctP and PLP-Dependent Aminotransferase PctC Catalyze the First Post-glycosylation Modification of Sugar Intermediate in Pactamycin Biosynthesis},
journal = {ChemBioChem},
year = 2018,
}
@article{CTT100755156,
author = {Akimasa Miyanaga and Ryuichi Takayanagi and Takashi Furuya and Ayano Kawamata and Tomohiro Itagaki and Yoshiharu Iwabuchi and Naoki Kanoh and Fumitaka Kudo and Tadashi Eguchi},
title = {Substrate Recognition by a Dual-Function P450 Monooxygenase Involved in FD-891 Biosynthesis},
journal = {ChemBioChem},
year = 2017,
}
@article{CTT100749760,
author = {Su-Hee Cho and Seung-Young Kim and Takeo Tomita and Taro Shiraishi and Jin-Soo Park and Shusuke Sato and Fumitaka Kudo and Tadashi Eguchi and Nobutaka Funa and Makoto Nishiyama and Tomohisa Kuzuyama},
title = {Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme},
journal = {ACS Chem. Biol.},
year = 2017,
}
@article{CTT100744573,
author = {Chisuga T and Miyanaga A and Kudo F and Eguchi T},
title = {Structural analysis of the dual function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an α,β-unsaturated thioester},
journal = {J Biol Chem},
year = 2017,
}
@article{CTT100747989,
author = {Shusuke Sato and Fumitaka Kudo and Seung-Young Kim and Tomohisa Kuzuyama and Tadashi Eguchi},
title = {Methylcobalamin-Dependent Radical SAM C-Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C-Methylation in Fosfomycin Biosynthesis},
journal = {Biochemistry},
year = 2017,
}
@article{CTT100744572,
author = {Cieślak J and Miyanaga A and Takaku R and Takaishi M and Amagai K and Kudo F and Eguchi T},
title = {Biochemical characterization and structural insight into aliphatic β-amino acid adenylation enzymes IdnL1 and CmiS6},
journal = {Proteins: Structure, Function, and Bioinformatics},
year = 2017,
}
@article{CTT100744357,
author = {Keita Amagai and Haruo Ikeda and Junko Hashimoto and Ikuko Kozone and Miho Izumikawa and Fumitaka Kudo and Tadashi Eguchi and Takemichi Nakamura and Hiroyuki Osada and Shunji Takahashi and Kazuo Shin-ya},
title = {Identification of a Gene Cluster for Telomestatin Biosynthesis and Heterologous Expression Using a Specific Promotor in a Clean Host},
journal = {Sci. Rep.},
year = 2017,
}
@article{CTT100737484,
author = {Fumitaka Kudo and Takahiro Tokumitsu and Tadashi Eguchi},
title = {Substrate Specificity of Radical S-Adenosyl-L-methionine Dehydratase AprD4 and Its Partner Reductase AprD3 in the C3′-Deoxygenation of Aminoglycoside Antibiotics},
journal = {J. Antibiot.},
year = 2017,
}
@article{CTT100714562,
author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Mechanisms of β-Amino Acid Incorporation in Polyketide Macrolactam Biosynthesis},
journal = {Curr. Opin. Chem. Biol.},
year = 2016,
}
@article{CTT100734359,
author = {Fumitaka Kudo and Takeshi Tsunoda and Makoto Takashima and Tadashi Eguchi},
title = {Five-membered Cyclitol Phosphate Formation by a myo-Inositol Phosphate Synthase Ortholog in the Biosynthesis of the Carbocyclic Nucleoside Antibiotic Aristeromycin},
journal = {ChemBioChem},
year = 2016,
}
@article{CTT100714590,
author = {宮永顕正 and 工藤史貴 and 江口正},
title = {天然物生合成酵素によるキャリアータンパク質の認識機構},
journal = {バイオサイエンスとインダストリー},
year = 2016,
}
@article{CTT100711106,
author = {Fumitaka Kudo and Yasunori Matsuura and Takaaki Hayashi and Masayuki Fukushima and Tadashi Eguchi},
title = {Genome Mining of the Sordarin Biosynthetic Gene Cluster from Sordaria araneosa Cain ATCC 36386: Characterization of Cycloaraneosene Synthase and GDP-6-Deoxyaltrose Transferase},
journal = {J. Antibiot.},
year = 2016,
}
@article{CTT100704203,
author = {Akimasa Miyanaga and Yuki Hayakawa and Mario Numakura and Junko Hashimoto and Kuniko Teruya and Takashi Hirano and Kazuo Shin-ya and Fumitaka Kudo and Tadashi Eguchi},
title = {Identification of the Fluvirucin B2 (Sch 38518) Biosynthetic Gene Cluster from Actinomadula fulva subsp. indica ATCC 53714: Substrate Specificity of β-amino Acid Selective Adenylating Enzyme FlvN},
journal = {Biosci. Biotechnol. Biochem.},
year = 2016,
}
@article{CTT100704202,
author = {Yuko Nishiyama and Tomohiro Ohmichi and Sayaka Kazami and Hiroki Iwasaki and Kousuke Mano and Yoko Nagumo and Fumitaka Kudo and Sosaku Ichikawa and Yoshiharu Iwabuchi and Naoki Kanoh and Tadashi Eguchi and Hiroyuki Osada and Takeo Usui},
title = {Vicenistatin Induces the Early Endosome-derived Vacuole Formation in Mammalian Cells},
journal = {Biosci. Biotechnol. Biochem.},
year = 2016,
}
@article{CTT100704213,
author = {Naoki Kanoh and Tomohiro Itagaki and Ayano Kawamata and Miho Takeuchi and Keisuke Hamada and Yoshiharu Iwabuchi and Tadashi Eguchi and Fumitaka Kudo and Takeo Usui},
title = {Synthesis and Structure-activity Relationship Study of FD891: Importance of the Side Chain and C8-C9 Epoxide for Cytotoxic Activity against Cancer Cells},
journal = {J. Antibiot.},
year = 2016,
}
@article{CTT100701323,
author = {Akimasa Miyanaga and Shohei Iwasawa and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi},
title = {Structure-based Analysis of the Molecular Interactions between Acyltransferase and Acyl Carrier Protein in Vicenistatin Biosynthesis},
journal = {Proc. Natl. Acad. Sci. USA},
year = 2016,
}
@article{CTT100701015,
author = {Fumitaka Kudo and Koichi Kawamura and Takashi Furuya and Hiroto Yamanishi and Atsushi Motegi and Akiko Komatsubara and Mario Numakura and Akimasa Miyanaga and Tadashi Eguchi},
title = {Parallel Post-Polyketide Synthase Modification Mechanism Involved in FD-891 Biosynthesis in Streptomyces graminofaciens A-8890},
journal = {ChemBioChem},
year = 2016,
}
@article{CTT100701945,
author = {Fumitaka Kudo and Tadashi Eguchi},
title = {Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinary of Old Drugs},
journal = {Chem. Rec.},
year = 2016,
}
@article{CTT100698953,
author = {Akane Hirayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Mechanism-based Trapping of the Quinonoid Intermediate Using the K276R Mutant of PLP-Dependent 3-Aminobenzoate Synthase PctV in the Biosynthesis of Pactamycin},
journal = {ChemBioChem},
year = 2015,
}
@article{CTT100685171,
author = {Fumitaka Kudo and Koichi Kawamura and Asuka Uchino and Akimasa Miyanaga and Mario Numakura and Ryuichi Takayanagi and Tadashi Eguchi},
title = {Genome Mining of Hitachimycin Biosynthetic Gene Cluster; Involvement of Phenylalanine-2,3-aminomutase in the Biosynthesis},
journal = {ChemBioChem},
year = 2015,
}
@article{CTT100682076,
author = {Ryohei Takeishi and Fumitaka Kudo and Mario Numakura and Tadashi Eguchi},
title = {Epimerization at C-3’’ in Butirosin Biosynthesis by an NAD(+)-Dependent Dehydrogenase BtrE and an NADPH-Dependent Reductase BtrF},
journal = {ChemBioChem},
year = 2015,
}
@article{CTT100677894,
author = {Akimasa Miyanaga and Jolanta Cieślak and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi},
title = {The Crystal Structure of Adenylation Enzyme VinN Reveals a Unique β-Amino Acid Recognition Mechanism},
journal = {J. Biol. Chem.},
year = 2014,
}
@article{CTT100676692,
author = {Fumitaka Kudo and Shota Hoshi and Taiki Kawashima and Toshiaki Kamachi and Tadashi Eguchi},
title = {Characterization of a Radical S‑Adenosyl‑L‑methionine Epimerase, NeoN, in the Last Step of Neomycin B Biosynthesis},
journal = {J. Am. Chem. Soc.},
year = 2014,
}
@article{CTT100674034,
author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi},
title = {Biosynthesis of Natural Products Containing β-Amino Acids},
journal = {Nat. Prod. Rep.},
year = 2014,
}
@article{CTT100667944,
author = {Yuji Shinohara and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {The Crystal Structure of the Amidohydrolase VinJ Shows a Unique Hydrophobic Tunnel for its Interaction with Polyketide Substrates},
journal = {FEBS Lett},
year = 2014,
}
@article{CTT100665526,
author = {Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi},
title = {Identification of Incednine Biosynthetic Gene Cluster: Characterization of Novel β-Glutamate-β-decarboxylase IdnL3},
journal = {J. Antibiot.},
year = 2013,
}
@article{CTT100664822,
author = {Mai Koide and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Characterization of Polyphosphate Glucokinase SCO5059 from Streptomyces coelicolor A3(2)},
journal = {Biosci. Biotechnol. Biochem},
year = 2013,
}
@article{CTT100660856,
author = {Keita Amagai and Ryoma Takaku and Fumitaka Kudo and Tadashi Eguchi},
title = {A Unique Amino Transfer Mechanism for Constructing the β-Amino Fatty Acid Starter Unit in the Biosynthesis of Macrolactam Antibiotic Cremimycin},
journal = {ChemBioChem},
year = 2013,
}
@article{CTT100658213,
author = {Akane Hirayama and Tadashi Eguchi and Fumitaka Kudo},
title = {A Single PLP-Dependent Enzyme PctV Catalyzes the Transformation of 3-Dehydroshikimate into 3-Aminobenzoate in the Biosynthesis of Pactamycin},
journal = {ChemBioChem},
year = 2013,
}
@article{CTT100642612,
author = {Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi},
title = {A Unique Pathway for the 3-Aminobutyrate Starter Unit from L-Glutamate through β-Glutamate during Biosynthesis of the 24-Membered Macrolactam Antibiotic, Incednine},
journal = {Org. Lett.},
year = 2012,
}
@article{CTT100640083,
author = {Fumitaka Kudo and Yusaku Asou and Moe Watanabe and Takashi Kitayama and Tadashi Eguchi},
title = {Potent Oligomerization and Macrocyclization Activity of the Thioesterase Domain of Vicenistatin Polyketide Synthase},
journal = {Synlett},
year = 2012,
}
@article{CTT100634881,
author = {Hilda Sucipto and Fumitaka Kudo and Tadashi Eguchi},
title = {The Last Step of Kanamycin Biosynthesis: Unique Deamination Reaction Catalyzed by the α-Ketoglutarate-dependent Nonheme Iron Dioxygenase KanJ and the NADPH Dependent Reductase KanK},
journal = {Angew. Chem. Int. Ed.},
year = 2012,
}
@article{CTT100630082,
author = {Keita Amagai and Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthetic Pathway of Macrolactam Polyketide Antibiotic Cremimycin},
journal = {Tetrahedron},
year = 2011,
}
@article{CTT100631073,
author = {Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi},
title = {A Natural Protecting Group Strategy To Carry an Amino Acid Starter Unit in the Biosynthesis of Macrolactam Polyketide Antibiotics},
journal = {J. Am. Chem. Soc.},
year = 2011,
}
@article{CTT100630342,
author = {Chiaki Nakano and Fumitaka Kudo and Tadashi Eguchi and Yasuo Ohnishi},
title = {Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (-)-epi-α-Bisabolol and (-)-Germacradiene-4-ol Synthases from Streptomyces citricolor},
journal = {ChemBioChem},
year = 2011,
}
@article{CTT100617878,
author = {Fumitaka Kudo and Takanori Yonezawa and Akiko Komatsubara and Kazutoshi Mizoue and Tadashi Eguchi},
title = {Cloning of the Biosynthetic Gene Cluster for Naphtoxanthene Antibiotic FD-594 from Streptomyces sp. TA-0256},
journal = {J. Antibiot.},
year = 2011,
}
@article{CTT100608685,
author = {Fumitaka Kudo and Atsushi Motegi and Kazutoshi Mizoue and Tadashi Eguchi},
title = {Cloning and Characterization of the Biosynthetic Gene Cluster of 16-Membered Macrolide Antibiotic FD-891: Involvement of a Dual Functional Cytochrome P450 Monooxygenase Catalyzing Epoxidation and Hydroxylation},
journal = {ChemBioChem},
year = 2010,
}
@article{CTT100596610,
author = {Fumitaka Kudo and Hilda Sucipto and Tadashi Eguchi},
title = {Enzymatic Activity of a Glycosyltransferase KanM2 Encoded in the Kanamycin Biosynthetic Gene Cluster},
journal = {J. Antibiot.},
year = 2009,
}
@article{CTT100592893,
author = {Fumitaka Kudo and Taiki Kawashima and Kenichi Yokoyama and Tadashi Eguchi},
title = {Enzymatic Preparation of Neomycin C from Ribostamycin},
journal = {J. Antibiot.},
year = 2009,
}
@article{CTT100590296,
author = {Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthetic Genes for Aminoglycoside Antibiotics},
journal = {J. Antibiot.},
year = 2009,
}
@article{CTT100564692,
author = {Kenichi Yokoyama and Daijiro Ohmori and Fumitaka Kudo and Tadashi Eguchi},
title = {Mechanistic Study on the Reaction of a Radical SAM Dehydrogenase BtrN by Electron Paramagnetic Resonance Spectroscopy},
journal = {Biochemistry},
year = 2008,
}
@article{CTT100558983,
author = {Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthetic Pathway of 24-Membered Macrolactam Glycoside Incednine},
journal = {Tetrahedron},
year = 2008,
}
@article{CTT100554300,
author = {Kenichi Yokoyama and Yasuhito Yamamoto and Fumitaka Kudo and Tadashi Eguchi},
title = {Involvement of Two Distinct N-Acetylglucosaminyltransferases and a Dual-Function Deacetylase in Neomycin Biosynthesis},
journal = {ChemBioChem},
year = 2008,
}
@article{CTT100546560,
author = {Kenichi Yokoyama and Mario Numakura and Fumitaka Kudo and Daijiro Ohmori and Tadashi Eguchi},
title = {Characterization and Mechanistic Study of a Radical SAM Dehydrogenase in the Biosynthesis of Butirosin},
journal = {J. Am. Chem. Soc.},
year = 2007,
}
@article{CTT100543115,
author = {Fumitaka Kudo and Yuko Kasama and Toshifumi Hirayama and Tadashi Eguchi},
title = {Cloning of the Pactamycin Biosynthetic Gene Cluster and Characterization of a Crucial Glycosyltransferase prior to a Unique Cyclopentane Ring Formation},
journal = {J. Antibiot.},
year = 2007,
}
@article{CTT100551122,
author = {Fumitaka Kudo and Takuya Fujii and Shunsuke Kinoshita and Tadashi Eguchi},
title = {Unique O-Ribosylation in the Biosynthesis of Butirosin},
journal = {Bioorg. Med. Chem.},
year = 2007,
}
@article{CTT100531578,
author = {Toshifumi Hirayama and Fumitaka Kudo and Zhen Huang and Tadashi Eguchi},
title = {Role of Glutamate 243 in the Active Site of 2-Deoxy-scyllo-inosose Synthase from Bacilllus circulans},
journal = {Bioorg. Med. Chem.},
year = 2007,
}
@article{CTT100531577,
author = {Toshifumi Hirayama and Hideyuki Tamegai and Fumitaka Kudo and Kazumasa Kojima and Katsumi Kakinuma and Tadashi Eguchi},
title = {Biosynthesis of 2-Deoxystreptamine-containing Antibiotics in Streptoalloteichus hindudtanus JCM 3268: Characterization of 2-Deoxy-scyllo-inosose Synthase},
journal = {J. Antibiot.},
year = 2006,
}
@article{CTT100541861,
author = {Fumitaka Kudo and Takashi Kitayama and Tadashi Eguchi and Katsumi Kakinuma},
title = {Macrolactam Formation Catalyzed by the Thioesterase Domain of Vicenistatin Polyketide Synthase},
journal = {Tetrahedron Lett.},
year = 2006,
}
@article{CTT100541860,
author = {Fumitaka Kudo and Yasuhito Yamamoto and Kenichi Yokoyama and Tadashi Eguchi and Katsumi Kakinuma},
title = {Biosynthesis of 2-Deoxystreptamine by Three Crucial Enzymes in Streptomyces fradiae NBRC12773},
journal = {J. Antibiot.},
year = 2005,
}
@article{CTT100540365,
author = {Fumitaka Kudo and Mario Numakura and Hideyuki Tamegai and Hideki Yamamoto and Tadashi Eguchi and Katsumi Kakinuma},
title = {Extended Sequence and Functional Analysis of the Butirosin Biosynthetic Gene Cluster in Bacillus circulans SANK 72073},
journal = {J. Antibitot.},
year = 2005,
}
@article{CTT100540368,
author = {Kenichi Yokoyama and Fumitaka Kudo and Mieko Kuwahara and Kousuke Inomata and Hideyuki Tamegai and Tadashi Eguchi and Katsumi Kakinuma},
title = {Stereochemical Recognition of Doubly Functional Aminotransferase in 2-Deoxystreptamine Biosynthesis},
journal = {J. Am. Chem. Soc.},
year = 2005,
}
@article{CTT100390189,
author = {Fumitaka Kudo and Kenichi Kawabe and Hisako Kuriki and Tadashi Eguchi and Katsumi Kakinuma},
title = {A New family of Pathways for Glucose-1-phosphate/Glucosamine-1-phosphate Nucleotidylyltransferase in the Biosynthetic Antibiotics},
journal = {J. Am. Chem. Soc.},
year = 2005,
}
@article{CTT100485247,
author = {Eriko Nango and Fumitaka Kudo and Tadashi Eguchi and Katsumi Kakinuma},
title = {Reaction Stereochemistry of 2-Deoxy-scyllo-inosose Synthase. The Key Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics},
journal = {Chem. Lett.},
year = 2003,
}
@article{CTT100485248,
author = {Hideyuki Tamegai and Eriko Nango and Ayumi Koike-Takeshita and Fumitaka Kudo and Katsumi Kakinuma},
title = {Significance of the 20 kDa Subunit of Heterodimeric 2-Deoxy-scyllo-inosose Synthase for the Biosynthesis of Butirosin Antibiotics in Bacillus circulans},
journal = {Bioscience, Biotechnololgy, and Biochemistry},
year = 2002,
}
@article{CTT100485251,
author = {Yasumasa Ota and Hideyuki Tamegai and Fumitaka Kudo and Hisako Kuriki and Aumi Koike-Takeshita and Tadashi Eguchi and Katsumi Kakinuma},
title = {Butirosin-biosynthetic Gene Cluster from Bacillus circulans},
journal = {J. Antibiot.},
year = 2000,
}
@article{CTT100485250,
author = {Nicholas Wu and Fumitaka Kudo and David E. Cane and Chaitan Khosla},
title = {Analysis of the Molecular Recognition Features of Individual Modules Derived from the Erythromycin Polyketide Synthase},
journal = {Journal of the American Chemical Society},
year = 2000,
}
@article{CTT100485252,
author = {Katsumi Kakinuma and Eriko Nango and Fumitaka Kudo and Yoshitaka Matsushima and Tadashi Eguchi},
title = {An Expeditious Chemo-enzymatic Route from Glucose to Catechol by the Use of 2-Deoxy-scyllo-inosose Synthase},
journal = {Tetrahedron Letters},
year = 2000,
}
@article{CTT100485254,
author = {Fumitaka Kudo and Yoshihiro Hosomi and Hideyuki Tamegai and Katsumi Kakinuma},
title = {Purification and Characterization of 2-Deoxy-scyllo-inosose Synthase Derived from Bacillus circulans. A Crucial Carbocyclization Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics},
journal = {Journal of Antibiotics},
year = 1999,
}
@article{CTT100485255,
author = {Noriaki Iwase and Fumitaka Kudo and Noriaki Yamauchi and Katsumi Kakinuma},
title = {Biochemical Studies on 2-Deoxy-scyllo-inosose, an Early Intermediate in the Biosynthesis of 2-Deoxystreptamine. VII. Substrate Specificity of 2-Deoxy-scyllo-inosose Synthase, the Starter Enzyme for 2-Deoxystreptamine Biosynthesis, toward Deoxyglucose-6-phosphates and Proposed Mechanism},
journal = {Bioscience, Biotechnology, and Biochemistry},
year = 1998,
}
@inproceedings{CTT100920653,
author = {立花 春香 and 小田切楓 and 鹿島 騰真 and 伏信 進矢 and 工藤史貴 and 江口正 and 宮永顕正},
title = {Ⅰ型ポリケタイド合成酵素における脱水酵素ドメインとアシルキャリアタンパク質間の相互作用解析},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920644,
author = {Fumitaka Kudo},
title = {Biosynthesis of Macrolactams with β-Amino Acid Polyketide Starter Unit},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920645,
author = {Fumitaka Kudo},
title = {Mechanistic Enzymology in Microbial Natural Product Biosynthesis Using Organic Chemistry Approaches},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920643,
author = {Fumitaka Kudo},
title = {Biosynthesis of Bacteriohopanepolyols - Enhancement of Solubility of Lipophilic Compounds in Aqueous Environments-},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920640,
author = {金子黎音 and 佐藤秀亮 and Rohmer Michel and 江口正 and 工藤史貴},
title = {Zymomonas mobilisが生産するバクテリオホパンポリオール生合成におけるサイクリトール部位の構築に関わる酵素の機能解析},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920639,
author = {坪井一馬 and 池崎睦実 and 川村紘一 and 江口正 and 工藤史貴},
title = {マクロラクタム抗生物質ヒタチマイシン生合成における推定異性化酵素の機能解析},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920638,
author = {千菅太一 and 翔太 滝浪 and 廖 増威 and 中野 祥吾 and 伊藤 創平 and 宮永顕正 and 工藤史貴 and 江口正},
title = {祖先型設計法を活用したモジュール型ポリケタイド合成酵素の構造解析},
booktitle = {},
year = 2024,
}
@inproceedings{CTT100920642,
author = {工藤 史貴},
title = {アミノグリコシド系抗生物質とポリケチド系抗生物質の構造多様性創出機構解明に向けた精密酵素機能解析},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100920649,
author = {千菅太一 and 岸川皓典 and 永井瑛 and 坪井一馬 and 村上聡 and 臼井 健郎 and 橋本絢子 and 新家 一男 and 宮永顕正 and 工藤史貴 and 江口正},
title = {放線菌Streptomyces graminofaciens A-8890が生産する マクロライド抗生物質の生合成における ポリケチド合成酵素の機能解析とエンジニアリング},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100920641,
author = {Fumitaka Kudo},
title = {Functional analysis of radical enzymes in natural product biosynthesis},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895304,
author = {平野健太朗 and 岸川皓典 and 坪井一馬 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロライド抗生物質FD-891 と virustomycin Aの生合成遺伝子改変},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895306,
author = {小田切楓 and 川崎大輔 and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質クレミマイシン生合成における脱水酵素とアシルキャリアタンパク質間の相互作用解析},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895305,
author = {千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {I型ポリケチド合成酵素におけるケト合成酵素様脱炭酸酵素とアシルキャリアタンパク質間相互作用の解明},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895303,
author = {横内大河 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ビリデノマイシンの生合成研究},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895302,
author = {WANGDAWEI and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ヒタチマイシン生合成におけるアデニル化酵素HitBの基質特異性の改変},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895301,
author = {池崎睦実 and 坪井一馬 and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ヒタチマイシン生合成における脱水素酵素HitM4の構造機能解析},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895300,
author = {安冨里菜 and 工藤史貴 and 江口正},
title = {アミノグリコシド系抗生物質イスタマイシンとスポラリシンの生合成研究},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100895299,
author = {坂本葵 and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {アミノグリコシド系抗生物質4′-デオキシブチロシンの生合成研究},
booktitle = {},
year = 2023,
}
@inproceedings{CTT100883608,
author = {野原麻耶 and 宮野夏妃 and 倉本怜季 and 宮永顕正 and 木下佳奈 and 石川文洋 and 高島克輝 and 工藤史貴 and 江口正 and 田邉元三},
title = {拡張型基質結合部位をもつアデニル化酵素の機能·構造解析および非天然型誘導体合成への応用},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100883607,
author = {宮永顕正 and 高橋壯太朗 and 川村紘一 and 栗原将平 and 中澤雄一郎 and 岩井南会子 and 南雲陽子 and 臼井健郎 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ヒタチマイシンの生合成研究},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100877479,
author = {Fumitaka Kudo and Michel Rohmer and TADASHI EGUCHI},
title = {Biosynthesis of bacteriohopanepolyols: characterization of radical SAM adenosylation enzyme HpnH},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100869563,
author = {楠部瑞樹 and 竹間琢自 and 岩﨑有紘 and 末永聖武 and 宮永顕正 and 工藤史貴 and 江口正},
title = {リングビアペプチンB推定生合成遺伝子クラスター中の二鉄含有酸化酵素の機能解析},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100877510,
author = {岩井南会子 and 南雲 陽子 and 工藤史貴 and 江口正 and 臼井 健郎},
title = {Hitachimycinによる膜機能破綻のメカニズム検討},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100877507,
author = {湊敦志 and 佐藤秀亮 and 丸山 千登勢 and 濱野 吉十 and 工藤史貴 and 江口正},
title = {1-アミノ-2-メチルシクロプロパンカルボン酸生合成におけるメチル基転移酵素の機能解析},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100869559,
author = {千菅太一 and 永井瑛 and 宮永顕正 and 工藤史貴 and 江口正},
title = {I型ポリケチド合成酵素ローディングモジュールにおけるケト合成酵素様脱炭酸酵素の機能構造解析},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100869560,
author = {永井瑛 and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {I型ポリケチド合成酵素ローディングモジュールにおけるケト合成酵素様脱炭酸酵素の変異体解析},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100869561,
author = {永田健司 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質生合成におけるアデニル化酵素とアシルキャリアタンパク質間の相互作用解析},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100869562,
author = {伏見政人 and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {I型ポリケチド合成酵素における同一モジュールのアシル基転移酵素とアシルキャリアタンパク質の相互作用解析},
booktitle = {},
year = 2022,
}
@inproceedings{CTT100877476,
author = {Fumitaka Kudo},
title = {Characterization of radical SAM enzymes in natural product biosynthesis},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100877477,
author = {Fumitaka Kudo},
title = {Biosynthetic studies on hybrid nonribosomal peptide-polyketide natural products},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100877497,
author = {佐藤 秀亮 and 工藤 史貴 and Rohmer Michel and 江口 正},
title = {バクテリオホパンポリオール生合成において炭素-炭素結合形成反応を触媒するラジカルSAM 酵素 HpnH の機能解析},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100858451,
author = {Fumitaka Kudo and Yukinobu Kitayama and Akimasa Miyanaga and Tadashi Eguchi},
title = {Kanamycin biosynthesis – Post-glycosylation modification of sugar moieties},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100858450,
author = {岩井 南会子 and 南雲 陽子 and 髙橋壯太朗 and 工藤史貴 and 江口正 and 臼井 健郎},
title = {Hitachimycinによる出芽酵母細胞内pHホメオスタシス障害},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100858445,
author = {岡田一歩 and 平山茜 and 工藤史貴 and 江口正},
title = {抗腫瘍抗生物質パクタマイシン生合成における脱水素酵素PctPの基質特異性},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100858443,
author = {平山太一 and 工藤史貴 and 江口正},
title = {アナモックス菌の細胞膜成分ラダラン脂質の推定生合成中間体の合成研究},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100858442,
author = {武藤舞 and 工藤史貴 and 江口正},
title = {ジテルペングリコシド抗生物質ソルダリンの麹菌異種発現系を用いた生合成解析},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100858441,
author = {佐藤秀亮 and 工藤史貴 and 江口正},
title = {バクテリオホパンポリオール生合成において炭素-炭素結合形成反応を触媒するラジカルSAM酵素HpnHの機能解析},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100845833,
author = {宮永顕正 and 北山幸延 and 工藤史貴 and 江口正},
title = {カナマイシン生合成酵素KanD2とKanJの結晶構造解析},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100845832,
author = {千菅太一 and 宮永顕正 and 栗原将平 and 安達成彦 and 川崎政人 and 守屋俊夫 and 千田俊哉 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ヒタチマイシン生合成におけるアデニル化酵素とキャリアタンパク質間相互認識機構},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100845830,
author = {永山大希 and 中澤雄一郎 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ヒタチマイシン生合成におけるポストPKS修飾酵素の機能解析},
booktitle = {},
year = 2021,
}
@inproceedings{CTT100836341,
author = {Fumitaka Kudo},
title = {Biosynthetic studies on β-amino acid-containing macrolactam antibiotics},
booktitle = {},
year = 2020,
}
@inproceedings{CTT100808981,
author = {石川文洋 and 宮永顕正 and 北山陽菜乃 and 工藤史貴 and 江口正 and 田邉 元三},
title = {アデニル化酵素の基質特異性の拡張および構造的基盤},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808982,
author = {宮永顕正 and 千菅太一 and 川﨑大輔 and 工藤史貴 and 江口正},
title = {クレミマイシン生合成における3-アミノノナン酸ユニット構築に関わる酵素の構造機能解析},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808979,
author = {石川文洋 and 宮永顕正 and 北山陽菜乃 and 工藤史貴 and 江口正 and 田邉 元三},
title = {アデニル化酵素のエンジニアリングによる基質許容性の拡張および構造的基盤},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808980,
author = {Fumihiro Ishikawa and Akimasa Miyanaga and Hinano Kitayama and Fumitaka Kudo and Tadashi Eguchi and Genzoh Tanabe},
title = {Reprogramming aryl acid adenylation domains for non-native building blocks},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808983,
author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthetic studies on 3-aminononanoic acid starter unit of cremimycin},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100836329,
author = {Fumitaka Kudo},
title = {Biosynthetic studies of macrocyclic polyketide antibiotics in Actinomycetes},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808984,
author = {Kosuke Kishikawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Engineering of macrocyclic polyketides biosynthesis in Streptomyces graminofaciens},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808985,
author = {Sotaro Takahashi and Yuichiro Nakazawa and Koichi Kawamura and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Engineering of hitachimycin biosynthesis},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100808978,
author = {石川文洋 and 宮永顕正 and 北山陽菜乃 and 工藤史貴 and 江口正 and 田邉元三},
title = {アデニル化酵素の基質特異性の拡張および構造的基盤},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100792472,
author = {川﨑大輔 and 千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質クレミマイシン生合成におけるsplit DHドメインの機能解析},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100792474,
author = {Jolanta Cieslak and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Functional and structural analysis of unique adenylation enzyme IdnL7 involved in biosynthesis of macrolactam antibiotic incednine},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100792470,
author = {北山幸延 and 宮永顕正 and 工藤史貴 and 江口正},
title = {カナマイシン生合成における脱水素酵素KanD2の基質認識機構},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100792471,
author = {岸川皓典 and 宮永顕正 and 工藤史貴 and 江口正},
title = {18員環マクロライド抗生物質Virustomycin Aの生合成遺伝子クラスター},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100792791,
author = {佐藤秀亮 and 宮永顕正 and 葛山智久 and 工藤史貴 and 江口正},
title = {ホスホマイシン生合成における新規加水分解酵素FomDの機能解析},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100792473,
author = {後藤絵菜 and 大内理紗子 and 宮永顕正 and 工藤史貴 and 江口正},
title = {ジソラゾール生合成におけるアシル基転移酵素とアシルキャリアプロテイン間の相互作用解析},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100806722,
author = {Shusuke Sato and Fumitaka Kudo and Tomohisa Kuzuyama and Tadashi Eguchi},
title = {Radical SAM C-Methylation in Fosfomycin Biosynthesis},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100836330,
author = {Fumitaka Kudo},
title = {Study on radical SAM C-methyltransferase Fom3 in fosfomycin biosynthesis},
booktitle = {},
year = 2019,
}
@inproceedings{CTT100780279,
author = {Shusuke Sato and Fumitaka Kudo and Tomohisa Kuzuyama and Tadashi Eguchi},
title = {C-Methylation mechanism in fosfomycin biosynthesis},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779586,
author = {工藤 史貴 and 平山 茜 and 張 家浩 and 宮永 顕正 and 江口 正},
title = {抗腫瘍抗生物質パクタマイシンの生合成研究},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779580,
author = {Fumitaka Kudo and Akimasa Miyanaga and Ryuichi Takayanagi and Takashi Furuya and Atsushi Motegi and Tadashi Eguchi},
title = {Study on a dual functional cytochrome P450 in the biosynthesis of macrolide antibiotic FD-891},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100780128,
author = {Fumitaka Kudo},
title = {Biosynthesis of aminoglycoside antibiotics},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779575,
author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthesis of 3-aminofatty acid starter units of macrolactam antibiotics},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779577,
author = {Ena Goto and Risako Ouchi and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Cross-linking reaction to investigate protein-protein interaction in polyketide synthases},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779578,
author = {Kosuke Kishikawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthesis of two macrolides produced by Streptomyces graminofaciens},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100780129,
author = {Fumitaka Kudo and Shuusuke Satou and TADASHI EGUCHI},
title = {Radical SAM enzymes in natural products biosynthesis},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779570,
author = {北山幸延 and 平山茜 and 宮永顕正 and 工藤史貴 and 江口正},
title = {カナマイシン生合成におけるカノサミン部位の構築機構},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779569,
author = {山口海斗 and 角田毅 and 宮永顕正 and 工藤史貴 and 江口正},
title = {ヌクレオシド系抗生物質アリステロマイシンの生合成における炭素五員環形成の立体},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779572,
author = {中澤雄一郎 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ヒタチマイシンの生合成におけるATP依存リガーゼHitBの基質特異性},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100779571,
author = {大内理紗子 and 石川文洋 and 後藤絵菜 and 木村真希 and 宮永顕正 and 田邉元三 and 工藤史貴 and 江口正},
title = {ポリケチド生合成におけるアシル基転移酵素とアシルキャリアタンパク質のクロスリンク反応の検討},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100780123,
author = {Fumitaka Kudo},
title = {Biosynthesis of β-amino acid containing macrolactam antibiotics},
booktitle = {},
year = 2018,
}
@inproceedings{CTT100780133,
author = {Fumitaka Kudo},
title = {Biosynthesis of Carbocyclic Nucleoside Aristeromycin},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100780131,
author = {佐藤 秀亮 and Kim Seung-Young and 葛山 智久 and 工藤 史貴 and 江口 正},
title = {ホスホマイシン生合成における C-メチル化機構},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100780136,
author = {Fumitaka Kudo},
title = {Radical SAM Enzymes Involved in Natural Product Biosynthesis},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100780285,
author = {平山茜 and 工藤史貴 and 江口正},
title = {抗腫瘍抗生物質パクタマイシンの生合成におけるアミノ基導入機構},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100780283,
author = {佐藤秀亮 and 工藤史貴 and 江口正 and 葛山智久},
title = {ホスホマイシン生合成におけるラジカルS-アデノシル-L-メチオニンC-メチル化酵素の機能解析},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100780140,
author = {Fumitaka Kudo and Takahiro Tokumitsu and Tadashi Eguchi},
title = {Functional analysis of radical SAM enzyme AprD4 and reductase AprD3 in the C3′-deoxygenation in apramycin biosynthesis},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100779562,
author = {髙栁龍一 and 古谷隆 and 宮永顕正 and 工藤史貴 and 江口正 and 川又綾乃 and 岩渕好治 and 叶直樹},
title = {マクロライド系抗生物質FD-891の生合成におけるシトクロムP450酸化酵素GfsFの基質特異性},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100779561,
author = {千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {Ⅲ型チオエステラーゼ SAV606の構造機能解析},
booktitle = {},
year = 2017,
}
@inproceedings{CTT100779612,
author = {千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質クレミマイシンの生合成における開始基質3-アミノノナン酸の構築機構-FAD依存酸化酵素CmiS2の構造機能解析},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100779611,
author = {Jolanta Cieslak and 宮永顕正 and 工藤史貴 and 江口正},
title = {Structural analysis of hydrophobic β-amino acid adenylation enzymes CmiS6 and IdnL1},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100779610,
author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi},
title = {Biosynthesis of Macrolactam Antibiotics in Actinomycetes},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100779605,
author = {千菅太一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {III 型チオエステラーゼの構造機構解析},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100749125,
author = {宮永顕正 and 早川雄基 and 沼倉真理緒 and 橋本絢子 and 新家一男 and 工藤史貴 and 江口正},
title = {Fluvirucin B2生合成遺伝子クラスターの同定と機能解析},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100779606,
author = {工藤史貴 and 角田毅 and 宮永顕正 and 高島惇 and 江口正},
title = {ヌクレオシド系抗生物質アリステロマイシンの生合成遺伝子のゲノムマイニング},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100780144,
author = {Fumitaka Kudo},
title = {Biosynthetic Study of Macrocyclic Polyketide Antibiotics},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100779600,
author = {安藤大史 and 川村紘一 and 工藤史貴 and 宮永顕正 and 江口正},
title = {ポリケチド抗生物質ヒタチマイシン生合成における PKS 後修飾機構解明に向けた遺伝子破壊実験},
booktitle = {},
year = 2016,
}
@inproceedings{CTT100779613,
author = {Akane Hirayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi},
title = {Characterization of PLP-dependent 3-aminobenzoate synthase PctV in pactamycin biosynthesis},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100749118,
author = {Akimasa Miyanaga and Jolanta Cieślak and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi},
title = {Functional and structural of β-amino acid-activating adenylation enzymes in macrolactam biosynthesis},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779615,
author = {西野晃太 and 宮永顕正 and 工藤史貴 and 江口正},
title = {生合成遺伝子破壊株を利用したヒタチマイシン類縁体生産の試み},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779616,
author = {岩沢翔平 and 宮永顕正 and 篠原雄治 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ビセニスタチン生合成に関わるアシル基転移酵素VinKの基質認識機構解析},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100749120,
author = {宮永顕正 and 篠原雄治 and 岩沢翔平 and Jolanta Cieślak and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ビセニスタチン生合成酵素の構造機能解析に基づくβ-アミノ酸スターター部位構築機構の解明},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779624,
author = {古谷隆 and 川村紘一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロライド系抗生物質FD-891生合成におけるポストPKS修飾酵素の機能解析},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100749123,
author = {宮永顕正 and 古谷隆 and 工藤史貴 and 江口正},
title = {FD-891生合成に関わるシトクロムP450酸化酵素GfsFの結晶構造解析},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779625,
author = {川村紘一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {ポリケチド抗生物質ヒタチマイシンの生合成遺伝子の機能解析},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779627,
author = {角田毅 and 高島惇 and 宮永顕正 and 工藤史貴 and 江口正},
title = {ヌクレオシド系抗生物質アリステロマイシン生合成に関わるOrf2の機能解析},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779623,
author = {平山茜 and 宮永顕正 and 工藤史貴 and 江口正},
title = {パクタマイシン生合成における3-アミノ安息香酸合成酵素の反応},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779622,
author = {森彩花 and 小出麻依 and 宮永顕正 and 工藤史貴 and 江口正},
title = {糖質から炭素六員環化合物への酵素的変換},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779626,
author = {早川雄基 and 川村紘一 and 宮永顕正 and 工藤史貴 and 江口正},
title = {非天然型基質投与によるヒタチマイシン類縁体生産},
booktitle = {},
year = 2015,
}
@inproceedings{CTT100779630,
author = {内野飛翔 and 沼倉真理緒 and 宮永顕正 and 江口正 and 工藤史貴},
title = {マクロラクタム抗生物質ヒタチマイシンのスターター部位構築に関わる酵素の機能解析},
booktitle = {},
year = 2014,
}
@inproceedings{CTT100749127,
author = {宮永顕正 and 篠原雄治 and 工藤史貴 and 江口正},
title = {ビセニスタチン生合成におけるATP依存性リガーゼVinNの結晶構造解析},
booktitle = {},
year = 2014,
}
@inproceedings{CTT100779634,
author = {篠原雄治 and 宮永顕正 and 工藤史貴 and 江口正},
title = {マクロラクタム抗生物質ビセニスタチン生合成に関わるペプチダーゼVinJのX線結晶構造解析},
booktitle = {},
year = 2013,
}
@inproceedings{CTT100585565,
author = {Ping Zhao and Jun-ya Ueda and Ikuko Kozone and Shuhei Chijiwa and Motoki Takagi and Fumitaka Kudo and Makoto Nishiyama and Kazuo Shin-ya and Tomohisa Kuzuyama},
title = {New glycosylated derivatives of versipelostatin, the GRP78/Bip molecular chaperone down-regulator, from Streptomyces versipellis 4083–SVS6},
booktitle = {Org. Biomol. Chem.},
year = 2009,
}
@inproceedings{CTT100390197,
author = {Fumitaka Kudo},
title = {Molecular Analysis of the Biosynthesis of 2-Deoxystreptamine-Containing Antibiotics},
booktitle = {Actinomycetologicia},
year = 2005,
}
@misc{CTT100836347,
author = {Fumitaka Kudo},
title = {Biosynthesis of Macrocyclic Polyketide Antibiotics},
year = 2020,
}
@misc{CTT100836346,
author = {Fumitaka Kudo},
title = {Carbon-carbon Bond Forming Radical SAM Enzymes in the Biosynthesis of Natural Products},
year = 2020,
}
@misc{CTT100836348,
author = {Fumitaka Kudo},
title = {Biosynthesis of Macrocyclic Polyketide Antibiotics},
year = 2020,
}
@misc{CTT100836345,
author = {Fumitaka Kudo},
title = {Carbon-carbon Bond Forming Radical SAM Enzymes in the Biosynthesis of Natural Products},
year = 2020,
}
@misc{CTT100836344,
author = {Fumitaka Kudo},
title = {Trends in drug discovery from natural sources -History of antibiotics-},
year = 2020,
}
@misc{CTT100780833,
author = {Fumitaka Kudo},
title = {Biosynthesis of macrocyclic polyketide antibiotics},
year = 2018,
}
@misc{CTT100780112,
author = {Fumitaka Kudo},
title = {Biosynthesis of macrocyclic polyketide antibiotics},
year = 2018,
}
@misc{CTT100780119,
author = {Fumitaka Kudo},
title = {Biosynthesis of macrocyclic polyketide antibiotics},
year = 2018,
}
@misc{CTT100780125,
author = {工藤史貴},
title = {抗腫瘍性マクロライド抗生物質 生合成マシナリーのリデザイン},
year = 2018,
}
@misc{CTT100780138,
author = {工藤史貴},
title = {天然物生合成に関わる ケミカルバイオロジー研究},
year = 2017,
}
@misc{CTT100781160,
author = {工藤史貴},
title = {マジックマッシュルームはどのように幻覚剤であるシロシビンを作るのか？},
year = 2017,
}
@misc{CTT100780134,
author = {工藤史貴},
title = {ポリケチド生合成マシナリーの 精密解析},
year = 2017,
}
@misc{CTT100780139,
author = {工藤史貴},
title = {抗腫瘍性マクロライド抗生物質生合成マシナリーのリデザイン},
year = 2017,
}
@misc{CTT100780142,
author = {Fumitaka Kudo},
title = {Recent Biosynthetic Study of Natural Products},
year = 2017,
}
@misc{CTT100678396,
author = {工藤史貴 and 宮永顕正 and 江口正},
title = {β-アミノ酸含有マクロラクタム抗生物質の生合成},
year = 2014,
}
@misc{CTT100791314,
author = {工藤史貴},
title = {ネオマイシン生合成酵素の機能解析から見えてきた生合成工学による構造多様化の可能性},
year = 2012,
}
@misc{CTT100574493,
author = {Fumitaka Kudo and Tadashi Eguchi},
title = {Biosynthetic Enzymes for the Aminoglycosides Butirosin and Neomycin},
year = 2009,
}
@misc{CTT100541862,
author = {工藤史貴 and 江口正},
title = {天然有機化合物の生合成に学ぶ アミノグリコシド抗生物質生合成研究の進歩},
year = 2006,
}
@misc{CTT100594365,
author = {工藤史貴},
title = {アミノ配糖体抗生物質の生合成における2-デオキシ-scyllo-イノソース合成酵素に関する研究},
year = 1999,
}
@misc{CTT100674897,
author = {江口正 and 工藤史貴},
title = {２－デオキシ－scyllo－イノソースの調製法
},
howpublished = {公開特許},
year = 2014,
month = {},
note = {特願2012-211752(2012/09/26), 特開2014-064513(2014/04/17)}
}
@misc{CTT100572827,
author = {柿沼勝己 and 工藤史貴 and 江口正},
title = {ラクタム及びラクトン合成酵素},
howpublished = {公開特許},
year = 2006,
month = {},
note = {特願2005-019886(2005/01/27), 特開2006-204169(2006/08/10)}
}
@phdthesis{CTT100594365,
author = {工藤史貴},
title = {アミノ配糖体抗生物質の生合成における2-デオキシ-scyllo-イノソース合成酵素に関する研究},
school = {東京工業大学},
year = 1999,
}