論文

• R.Ohki, T.Tsurimoto, F.Ishikawa. In vitro reconstitution of the end-replication problem., Mol. Cell. Biol., Vol. 21, No. 17, pp. 5753-5766, 2001.
• J.Ohno, Y.Horio, Y.Sakido, Y.Hasegawa, M.Takahashi, J.Nishizawa, H.Saito, F.Ishikawa, K.Shimokata. Telomerase activation and p53 mutations in urethane-induced A/J mouse lung tumor development, Carcinogenesis, Vol. 22, No. 5, pp. 751-756, 2001.
• J.Kanoh, F.Ishikawa. SpRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast., Curr. Biol., Vol. 11, pp. 1624-1630, 2001.
• F.Ishikawa, T.Hoque. Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres., J. Biol. Chem., Vol. 276, No. 7, pp. 5059-5067, 2001.
• M.Kuramoto, K.Ohsumi, T.Kishimoto, F.Ishikawa. Identification and analyses of the Xenopus TERT gene that encodes the catalytic subunit of telomerase, GENE, Vol. 277, No. 1-2, pp. 101-110, 2001.
• FUYUKI ISHIKAWA. Aging clock, the watchmaker's masterpiece., Cell. Mol. Life Sci., Vol. 57, No. 5, pp. 698-704, 2000.
• F.Ishikawa, K.Tatematsu, T.Yamazaki. MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase., Genes to Cells, Vol. 5, No. 8, pp. 677-688, 2000.
• F.Ishikawa, Y.Takahashi, M.Kuro-o. Aging mechanisms., Proc. Natl. Acad. Sci. USA, Vol. 97, No. 23, pp. 12407-12408, 2000.
• T.Yamaguchi, R.Yamada, A.Tomikawa, K.Shudo, M.Saito, F.Ishikawa, M.Saneyoshi. Recognition of 2ﾕ-deoxy-L-ribonucleoside 5ﾕ-triphosphates by human telomerase, Biochem. Biophys. Res. Commun, Vol. 279, No. 2, pp. 475-481, 2000.
• G.Kajiyama., Y.Kawakami, M.Kitamoto, T.Nakanishi, W.Yasui, E.Tahara, J.Nakayama, F.Ishikawa, H.Tahara, T.Ide. Immuno-histochemical detection of human telomerase reverse transcriptase in human liver tissues., Oncogene, Vol. 19, No. 34, pp. 3888-3893, 2000.
• T.Ide, H.Tahara, W.Yasui, E.Tahara, J.Fujimoto, K.Ito, K.Tamai, J.Nakayama, F.Ishikawa, E.Tahara. Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections, Oncogene, Vol. 18, No. 8, pp. 1561-1567, 1999.
• F. Ishikawa, X. Yuan, S. Ishibashi, S. Hatakeyama, M. Saito, J. Nakayama, M. Nikaido, T. Haruyama, Y. Watanabe, H. Iwata. Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice., Genes to Cells, Vol. 4, No. 10, pp. 563-572, 1999.
• F.Ishikawa, A.Matsuura, T.Naito. Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3+ and tel1+ are parts of two regulatory networks independent of the downstream protein kinases chk1+ and cds1+, Genetics, Vol. 152, No. 4, pp. 1501-1512, 1999.
• E.Tahara, W.Yasui, E.Tahara, H.Tahara, J.Fujimoto, K.Naka, J.Nakayama, F.Ishikawa, T.Ide. Immunohistochemical Detection of Human Telomerase Reverse Transcriptase in Normal Mucosa and Precancerous Lesions of the Stomach, Jpn. J. Cancer Res., Vol. 90, No. 6, pp. 589-595, 1999.
• M.Katahira, T.Nagata, Y.Kurihara, G.Matsuda, J.Saeki, T.Kohno, Y.Yanagida, F.Ishikawa, S.Uesugi. Structure and Interactions with RNA of the N-Terminal UUAG-specific RNA-binding Domain of hnRNP D0, J. Mol. Biol., Vol. 287, No. 2, pp. 221-237, 1999.
• F.Ishikawa, T.Naito. Why do we have linear chromosomes? - a matter of Adam and Eve, Mut. Res., Vol. 434, No. 2, pp. 99-107, 1999.
• F.Ishikawa, S.Hatakeyama, M.Osawa, M.Omine. JTB, a novel membrane protein gene at 1q21 rearranged in a jumping translocation, Oncogene, Vol. 18, No. 12, pp. 2085-2090, 1999.
• F.Ishikawa, T.Naito, A.Matsuura. Circular chromosome formation in a fission yeast mutant defective in two ATM-homologues, Nature Genetics, Vol. 20, No. 2, pp. 203-206, 1998.
• F.Ishikawa, J.Nakayama, H.Tahara, E.Tahara, M.Saito, K.Ito, H.Nakamura, T.Nakanishi, E.Tahara, T.Ide. Telomerase activation by hTRT in human notmal fibroblasts and hepatocellular carcinomas., Nature Genetics., Vol. 18, No. 1, pp. 65-68, 1998.
• F.Ishikawa, S.Hatakeyama, K.Fujita, M.Omine. Shortened Telomeres Involved in a Case With a Jumping Translocation at 1q21, Blood, Vol. 91, No. 5, pp. 1514-1519, 1998.
• FUYUKI ISHIKAWA. Research analysis : FISH goes with the flow., Nature Biotechnology, Vol. 16, No. 8, pp. 723-724, 1998.
• F.Ishikawa, M.Yamada, N.Hayatsu, A.Matsuura. Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element is induced in survivors defective for telomerase, J. Biol. Chem., Vol. 273, No. 50, pp. 33360-33366, 1998.
• FUYUKI ISHIKAWA. Expression of telomerase catalytic component, telomerase reverse transcriptase, in human gastric carcinomas, Jpn. J. Cancer Res., Vol. 89, No. 11, pp. 1099-1103, 1998.
• F.Ishikawa, T.Saito, Y.Matsuda, T.Suzuki, A.Hayashi, X.Yuan, M.Saito, J.Nakayama, T.Hori. Comparative gene mapping of the human and mouse TEP1 genes, which encode one protein component of telomerases., Genomics., Vol. 46, No. 1, pp. 46-50, 1997.
• FUYUKI ISHIKAWA. A review article : Regulation mechanisms of mammalian telomerases., Biochemistry(Moscow), Vol. 62, No. 11, pp. 1332-1337, 1997.
• FUYUKI ISHIKAWA. News and Viens : A tale of mice without 'tails'., Nature Genetics, Vol. 17, No. 3, pp. 257-258, 1997.
• F.Ishikawa, S.Hatakeyama. ICE : a novel and efficient method for isolation of chromosomal ends., Genetic Analysis : Biomolecular Engineering, Vol. 14, No. 2, pp. 45-46, 1997.
• FUYUKI ISHIKAWA. Telomere crisis, the driving force in cancer cell evolution, Biochem. Biophys. Res. Commun., Vol. 230, No. 1, pp. 1-6, 1997.
• F.Ishikawa, J.Nakayama, M.Saito, H.Nakamura, A.Matsuura. TLP1 : A gene encoding a protein component of mammalian telomerase is a novel member of WD-repeats family, Cell, Vol. 88, No. 6, pp. 875-884, 1997.
• FUYUKI ISHIKAWA. A review article: Telomere crisis in leukemia, Intl. J. Hematol, Vol. 65, No. 4, pp. 355-364, 1997.
• F.Ishikawa, K.Tatematsu, J.Nakayama, M.Danbara, S.Shionoya, H.Sato, M.Omine. A novel quantitativestretch PCR assay, that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias, Oncogene, Vol. 13, No. 10, pp. 2265-2274, 1996.
• F.Ishikawa, Y.Kajita, J.Nakayama, M.Aizawa. The UUAG-Specific RNA Binding Protein,heterogeneous nuclear ribonucleoprotein DO:Common Modular Structure and Binding Properties of the 2xRBD-Gly Family, J.Biol.Chem., Vol. 270, No. 38, pp. 22167-22175, 1995.
• T.Cech, F.Ishikawa, M.Matunis, G.Dreyfuss. Nuclear Proteins that Bind the Pre-mRNA 3' Splice Site Sequence r(UUAG/G) and the Human Telomeric DNA Sequence d(TTAGGG)n, Mol. Cell. Biol., Vol. 13, No. 7, pp. 4301-4310, 1993.
• H.Hirai, K.Sugimoto, H.Toyoshima, R.Sakai, K.Miyagawa, K.Hagiwara, F.Ishikawa, F.Takaku, Y.Yazaki. Frequent Mutations in the p53 Gene in Human Myeloid Leukemia Cell Lines, Blood, Vol. 79, No. 9, pp. 2378-2383, 1992.
• F.Takaku, K.Hagiwara, G.Stenman, H.Honda, P.Sahlin, A.Andersson, K.Miyazono, C.-H.Heldin, F.Ishikawa. Organization and chromosomal localization of the human platelet-derived endothelial cell growth factor gene, Mol. Cell. Biol., Vol. 11, No. 4, pp. 2125-2132, 1991.
• F.Takaku, K.Sugimoto, H.Toyoshima, R.Sakai, K.Miyagawa, K.Hagiwara, H.Hirai, F.Ishikawa. Mutations of the p53 gene in lymphoid leukemia, Blood, Vol. 77, No. 6, pp. 1153-1156, 1991.
• K.Miyazono, C.-H.Heldin, U.Hellman, F.Ishikawa. Purification cloning, and expression of Platelet-derived Endothelial cell Growth Factor, Methods in Enzymology, Vol. 198, pp. 383-391, 1991.
• H.Mano, F.Ishikawa, I.Nishida, H.Hirai, F.Takaku. A novel protein-tyrosine kinase, tec, is preferentially expressed in liver, Oncogene, Vol. 5, No. 12, pp. 1781-1786, 1990.
• K.Usuki, NE.Heldin, K.Miyazono, F.Ishikawa, F.Takaku, B.Westermark, CH.Heldin. Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture , Proc. Natl. Acad. Sci. , USA, Vol. 86, No. 19, pp. 7427-7431, 1989.
• F.Ishikawa, K.Miyazono, U.Hellman, H.Drexler, C.Wernstedt, K.Hagiwara, K.Usuki, F.Takaku, W.Heldin CH. Identification of angiogenic activity and the cloning and expression of platelet derived endothelial cell growth factor , Nature, Vol. 338, No. 6216, pp. 557-562, 1989.
• F.Ishikawa, R.Sakai, M.Ochiai, F.Takaku, T.Sugimura, M.Nagao. Identification of a transforming activity suppressing sequence in the c-raf oncogene, Oncogene, Vol. 3, No. 6, pp. 653-658, 1988.
• F.Ishikawa, F.Takaku, M.Nagao, T.Sugimura. Rat c-raf oncogene activation by a rearrangement that produces a fused protein, Mol. Cell. Biol., Vol. 7, No. 3, pp. 1226-1232, 1987.
• F.Ishikawa, F.Takaku, K.Hayashi, M.Nagao, T.Sugimura. Activation of rat c-raf during transfection of hepatocellular carcinons DNA, Proc. Natl. Acad. Sci. USA, Vol. 83, No. 10, pp. 3209-3212, 1986.

著書

• 石川冬木. Annual Reviw 内分泌，代謝, 中外医学社, 中外医学社, pp. 24-28, 2000.
• 鍋島陽一, 北　徹, 石川冬木（監訳）. 老化のバイオロジー Robert Arking 著, メディカル・サイエンス・インターナショナル社, メディカル・サイエンス・インターナショナル社, 2000.
• 石川冬木, 中山潤一. ＲＮＡ研究の最前線, Springer-Verlag, Springer-Verlag, 2000.
• 石川冬木. Bio Science新用語ライブラリー細胞周期(第２版), 羊土社, 羊土社, 1999.
• 石川冬木. 癌細胞におけるテロメラーゼの活性化，癌化のメカニズムを解く－医学＆サイエンスシリーズ－, 羊土社, 羊土社, 1998.
• 一瀬白帝, 鈴木宏治, 石川冬木. 図説　分子病態学, 中外医学社, 中外医学社, 1995.
• 平井久丸, 石川冬木. 遺伝子診断 臨床医のための実験医学シリーズ１３, 羊土社, 羊土社, 1993.
• 高久史麿, 石川冬木. 分子血液学, 南江堂, 南江堂, 1991.

学位論文

• rafがん遺伝子の活性化抑制配列の同定,  本文,  Doctor of Medicine,  The University of Tokyo,  1990/--/--, 

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