論文

• Saki Goto, Yuki Miyahara, Seiichi Taguchi, Takeharu Tsuge, Ayaka Hiroe. Enhanced production of (R)-3-hydroxybutyrate oligomers by coexpression of molecular chaperones in recombinant Escherichia coli harboring a polyhydroxyalkanoate synthase derived from Bacillus cereus YB-4, Microorganisms, Vol. 10, No. 2, 458, Feb. 2022.
• Tetsuo Sakurai, Shoji Mizuno, Yuki Miyahara, Ayaka Hiroe, Seiichi Taguchi, Takeharu Tsuge. Optimization of culture conditions for secretory production of 3-hydroxybutyrate oligomers using recombinant Escherichia coli, Frontiers in Bioengineering and Biotechnology, Vol. 10, 829134, Feb. 2022.
• Shoji Mizuno, Tetsuo Sakurai, Mikito Nabasama, Kyouhei Kawakami, Ayaka Hiroe, Seiichi Taguchi, Takeharu Tsuge. The influence of medium composition on microbial secretory production of hydroxyalkanoate oligomers, J Gen Appl Microbiol, Vol. 67, No. 4, pp. 134-141, Oct. 2021.
• Ayaka Hiroe, Tetsuo Sakurai, Shoji Mizuno, Yuki Miyahara, Saki Goto, Mariko Yamada, Takeharu Tsuge, Seiichi Taguchi. Microbial oversecretion of (R)-3-hydroxybutyrate oligomer with diethylene glycol terminal as a macromonomer for polyurethane synthesis, Int J Biol Macromol, Vol. 167, pp. 1290-1296, Jan. 2021.
• Yuki Miyahara, Ayaka Hiroe, Takeharu Tsuge, Seiichi Taguchi. Microbial secretion platform for 3-hydroxybutyrate oligomers and its end-capped forms using chain transfer reaction-mediated polyhydroxyalkanoate synthases, Biotechnol. J., Vol. 14, No. 12, Dec. 2019.
• Fakhrul Ikhma Mohd Fadzil, Shoji MIzuno, Ayaka Hiroe, Christopher Nomura, Takeharu Tsuge. Low carbon concentration feeding improves medium-chain-length polyhydroxyalkanoate production in Escherichia coli strains with defective β-oxidation, Front. Bioeng. Biotechnol., Vol. 6, No. 178, Dec. 2018.
• Ayaka Hiroe, Suzuran Watanabe, Makoto Kobayashi, Christopher T. Nomura, Takeharu Tsuge. Increased synthesis of poly(3-hydroxydodecanoate) by random mutagenesis of polyhydroxyalkanoate synthase, Appl. Microbiol. Biotechnol., Vol. 102, No. 18, pp. 7927–7934, Sept. 2018.
• Pengtao Huang, Takaya Okoshi, Shoji Mizuno, Ayaka Hiroe, Takeharu Tsuge. Gas chromatography-mass spectrometry-based monomer composition analysis of medium-chain-length polyhydroxyalkanoates biosynthesized by Pseudomonas spp., Biosci. Biotechnol. Biochem., Vol. 82, No. 9, pp. 1615-1623, Sept. 2018.
• Shoji Mizuno, Yukio Enda, Azusa Saika, Ayaka Hiroe, Takeharu Tsuge. Biosynthesis of polyhydroxyalkanoates containing 2-hydroxy-4-methylvalerate and 2-hydroxy-3-phenylpropionate units from a related or unrelated carbon source, J. Biosci. Bioeng., Vol. 125, pp. 295-300, Mar. 2018.
• Sho Furutate, Hitomi Nakazaki, Koki Maejima, Ayaka Hiroe, Hideki Abe, Takeharu Tsuge. Biosynthesis and characterization of novel polyhydroxyalkanoate copolymers consisting of 3-hydroxy-2-methylbutyrate and 3-hydroxyhexanoate, J. Polym. Res., Vol. 24, No. 12, pp. 221, Dec. 2017.
• Takahiro Kihara, Ayaka Hiroe, Manami Ishii-Hyakutake, Kouhei Mizuno, Takeharu Tsuge. Bacillus cereus-type polyhydroxyalkanoate biosynthetic gene cluster contains R-specific enoyl-CoA hydratase gene, Biosci. Biotechnol. Biochem., Vol. 81, No. 8, pp. 1627–1635, July 2017.
• Shoji Mizuno, Ayaka Hiroe, Toshiaki Fukui, Hideki Abe, Takeharu Tsuge. Fractionation and thermal characteristics of biosynthesized polyhydoxyalkanoates bearing aromatic groups as side chains, Polym J, Vol. 49, pp. 557–565, July 2017.
• Ayaka Hiroe, Naoki Ishii, Daisuke Ishii, Taizo Kabe, Hideki Abe, Tadahisa Iwata, Takeharu Tsuge. Uniformity of monomer composition and material properties of medium-chain-length polyhydroxyalkanoates biosynthesized from pure and crude fatty acids, ACS Sustainable Chem. Eng., Vol. 4, No. 12, pp. 6905-6911, 2016.
• Takeharu Tsuge, Shun Sato, Ayaka Hiroe, Koya Ishizuka, Hiromi Kanazawa, Yoshitsugu Shiro, Tamao Hisano. Contribution of the distal pocket residue to the acyl-chain-length specificity of (R)-specific enoyl-CoA hydratases from Pseudomonas spp., Appl. Environ. Microbiol., Vol. 81, No. 23, pp. 8076 – 8083, Dec. 2015.
• Ayaka Hiroe, Masaya Shiraishi, Kouhei Mizuno, Takeharu Tsuge. Behavior of different polyhydroxyalkanoate synthases in response to the ethanol level in Escherichia coli cultures, Polymer Journal, Vol. 47, pp. 767–770, Nov. 2015.
• Kazunori Ushimaru, Yoriko Watanabe, Ayaka Hiroe, Takeharu Tsuge. A single-nucleotide substitution in phasin gene leads to enhanced accumulation of polyhydroxyalkanoate (PHA) in Escherichia coli harboring Aeromonas caviae PHA biosynthetic operon, J. Gen. Appl. Microbiol., Vol. 61, No. 2, pp. 63–66, May 2015.
• Shoji Mizuno, Shiori Katsumata, Ayaka Hiroe, Takeharu Tsuge. Biosynthesis and thermal characterization of polyhydroxyalkanoates bearing phenyl and phenylalkyl side groups, Polym. Degrad. Stab., Vol. 109, pp. 379-384, Nov. 2014.
• Nicholas M. Thomson, Ayaka Hiroe, Takeharu Tsuge, David K. Summers, Easan Sivaniah. Efficient molecular weight control of bacterially synthesised polyesters by alcohol supplementation, Journal of Chemical Technology and Biotechnology, Vol. 89, pp. 1110–1114, July 2014.
• Ayaka Hiroe, Manami Hyakutake, Nicholas Thomson, Easan Sivaniah, Takeharu Tsuge. Endogenous ethanol affects biopolyester molecular weight in recombinant Escherichia coli, ACS Chem. Biol., Vol. 8, pp. 2568−2576, Sept. 2013.
• Ayaka Hiroe, Kazunori Ushimaru, Takeharu Tsuge. Characterization of polyhydroxyalkanoate (PHA) synthase derived from Delftia acidovorans DS-17 and the influence of PHA production in Escherichia coli, J. Biosci. Bioeng., Vol. 115, No. 6, pp. 633-638, May 2013.
• Ayaka Hiroe, Kenji Tsuge, Christopher T. Nomura, Mitsuhiro Itaya, Takeharu Tsuge. Rearrangement of gene order in the phaCAB operon leads to effective production of ultrahigh-molecular-weight poly[(R)-3-hydroxybutyrate] in genetically engineered Escherichia coli, Appl. Environ. Microbiol., Vol. 78, No. 9, pp. 3177–3184, Apr. 2012.

著書

• 廣江綾香, 柘植丈治. 3章3節 微生物により合成する生分解性プラスチック材料, 微生物を活用した有用物質の製造技術, CMC出版, May 2023.
• 廣江綾香, 柘植丈治. （第2編 第１章 第１節）さまざまな側鎖を有する微生物産生ポリエステルの開発, 海洋汚染問題を解決する生分解性プラスチック開発 ～分解性評価から新素材まで～, エヌ・ティー・エス, Feb. 2023.
• Yuki Miyahara, Ayaka Hiroe, Shunsuke Sato, Takeharu Tsuge, Seiichi Taguchi. Chapter 8: Microbial Polyhydroxyalkanoates (PHAs): From Synthetic Biology to Industrialization, Biopolymers for Biomedical and Biotechnological Applications, Wiley, pp. 231-264, 2020.
• Ayaka Hiroe, Sho Furutate, Shoji Mizuno, Takeharu Tsuge. 3HB-based Copolymers and Unusual PHA Homopolymers, Recent Advances in Biotechnology, Bentham Science, Vol. 2, 403-435, 2016.

国際会議発表 (査読なし・不明)

• Hironori MARUBAYASHI, Shiori KATSUMATA, Ayaka HIROE, Takeharu TSUGE, Takaaki HIKIMA, Masaki TAKATA, Tadahisa IWATA. Molecular, Crystal, and Higher-Order Structures of Medium-Chain-Length Poly[(R)-3-hydroxyalkanoate]s, The 10th SPSJ International Polymer Conference (IPC2014), The 10th SPSJ International Polymer Conference (IPC2014), The Society of Polymer Science, Japan, p. 78, Dec. 2014.
• Hironori MARUBAYASHI, Shiori KATSUMATA, Ayaka HIROE, Takeharu TSUGE, Takaaki HIKIMA, Masaki TAKATA, Tadahisa IWATA. Molecular, Crystal, and Higher-Order Structures of Microbial Poly[(R)-3-hydroxyalkanoate]s with Long Alkyl Side Chains, ICR Symposium on Polymer Crystals 2014, Oct. 2014.

国内会議発表 (査読なし・不明)

• 丸林 弘典, 勝又 しおり, 廣江 綾香, 柘植 丈治, 引間 孝明, 高田 昌樹, 岩田 忠久. X線繊維回折法を用いたポリ[(R)-3-ヒドロキシデカノエート]の結晶構造解析, 第63回高分子学会年次大会, 第63回高分子学会年次大会予稿集, Vol. 63, No. 1, pp. 3671-3672, May 2014.

その他の論文・著書など

• 廣江綾香, 柘植丈治. 微生物を利用したバイオプラスチック合成～中鎖ホモポリヒドロキシアルカン酸編～, ポリマーTECH, Vol. 6, July 2020.
• 廣江綾香, 柘植丈治. バイオマス資源からの高性能ポリエステル合成, ケミカルエンジニヤリング, Vol. 58, No. 8, pp. 598-605, Aug. 2013.

[ BibTeX 形式で保存 ]    [ 論文・著書をCSV形式で保存 ]    [ 特許をCSV形式で保存 ]