論文

• Matthew N. Saxton, Tatsuya Morisaki, Diego Krapf, Hiroshi Kimura, Timothy J. Stasevich. Live-cell imaging uncovers the relationship between histone acetylation, transcription initiation, and nucleosome mobility, Science Advances, Oct. 2023.  公式リンク  
  
• Hiroshi Ochiai, Hiroaki Ohishi, Yuko Sato, Hiroshi Kimura. Organization of transcription and 3D genome as revealed by live-cell imaging, Current Opinion in Structural Biology, Aug. 2023.  公式リンク  
  
• Haruka Oda, Yuko Sato, Shigehiro A. Kawashima, Yusuke Fujiwara, Máté Pálfy, Edlyn Wu, Nadine L. Vastenhouw, Motomu Kanai, Hiroshi Kimura. Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo, Biology Open, May 2023.  公式リンク  
  
• Watanya Trakarnphornsombat, Hiroshi Kimura. Live-cell tracking of γ-H2AX kinetics reveals the distinct modes of ATM and DNA-PK in the immediate response to DNA damage, Journal of Cell Science, Apr. 2023.  公式リンク  
  
• Junya Adachi, Haruka Oda, Toshiaki Fukushima, Beni Lestari, Hiroshi Kimura, Hiroka Sugai, Kentaro Shiraki, Rei Hamaguchi, Kohei Sato, Kazushi Kinbara. Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection, Analytical Chemistry, Mar. 2023.  公式リンク  
  
• Hiroki Ozawa, Azusa Kambe, Kodai Hibi, Satoshi Murakami, Akira Oikawa, Tetsuya Handa, Katsunori Fujiki, Ryuichiro Nakato, Katsuhiko Shirahige, Hiroshi Kimura, Nobuaki Shiraki, Shoen Kume. Transient Methionine Deprivation Triggers Histone Modification and Potentiates Differentiation of Induced Pluripotent Stem Cells, Stem Cells, Mar. 2023.  公式リンク  
  
• Fumiaki Nakamura, Hiroshi Kimura, Nobuhiro Fusetani, Yoichi Nakao. Two Onnamide Analogs from the Marine Sponge Theonella conica: Evaluation of Geometric Effects in the Polyene Systems on Biological Activity, Molecules, Mar. 2023.  公式リンク  
  
• Junya Adachi, Haruka Oda, Toshiaki Fukushima, Beni Lestari, Hiroshi Kimura, Hiroka Sugai, Kentaro Shiraki, Rei Hamaguchi, Kohei Sato, Kazushi Kinbara. Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection, Analytical Chemistry, 95, 5196–5204, Mar. 2023.
• Misako Tanaka, Hiroyuki Harada, Hiroshi Kimura. The role of H3K9me3 in oral squamous cell carcinoma, Biochemical and Biophysical Research Communications, Jan. 2023.  公式リンク  
  
• Ksenia Kuznetsova, Noémie M. Chabot, Martino Ugolini, Edlyn Wu, Manan Lalit, Haruka Oda, Yuko Sato, Hiroshi Kimura, Florian Jug, Nadine Vastenhouw. Nanog organizes transcription bodies, Current Biology, Vol. 33, No. 1, pp. 164-173.e5, Jan. 2023.  公式リンク  
  
• Fukuda, Kei, Shimi, Takeshi, Shimura, Chikako, Ono, Takao, Suzuki, Takehiro, Onoue, Kenta, Okayama, Satoko, Miura, Hisashi, Hiratani, Ichiro, Ikeda, Kazuho, Okada, Yasushi, Dohmae, Naoshi, Yonemura, Shigenobu, Inoue, Azusa, Kimura, Hiroshi, Shinkai, Yoichi, Hiroshi Kimura. Epigenetic plasticity safeguards heterochromatin configuration in mammals, Nucleic Acids Research, 2023.  公式リンク  
  
• Nishino, Miyu, Imaizumi, Hiromasa, Yokoyama, Yuhki, Katahira, Jun, Kimura, Hiroshi, Matsuura, Nariaki, Matsumura, Miki, Hiroshi Kimura. Histone methyltransferase SUV39H1 regulates the Golgi complex via the nuclear envelope-spanning LINC complex, Plos One, 2023.  公式リンク  
  
• Ksenia Kuznetsova, Noemie M. Chabot, Martino Ugolini, Edlyn Wu, Manan Lalit, Haruka Oda, Yuko Sato, Hiroshi Kimura, Florian Jug, Nadine L. Vastenhouw. Nanog organizes transcription bodies, Current Biology, Vol. 33, No. 1, pp. 164-173.e5, Dec. 2022.  公式リンク  
  
• Yohei Kono, Stephen A. Adam, Yuko Sato, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS, Journal of Cell Biology, Dec. 2022.  公式リンク  
  
• Hiroaki Ohishi, Seiru Shimada, Satoshi Uchino, Jieru Li, Yuko Sato, Manabu Shintani, owada hitoshi, Yasuyuki Ohkawa, Alexandros Pertsinidis, Takashi Yamamoto, Hiroshi Kimura, Hiroshi Ochiai. STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity, Nature Communications, Vol. 13, No. 1, Dec. 2022.  公式リンク  
  
• Naoki Kamiya, Kazuki Kuramoto, Kento Takishima, Tatsuya Yumoto, Haruka Oda, Takeshi Shimi, Hiroshi Kimura, Michio Matsushita, Satoru Fujiyoshi. Superfluid helium nanoscope insert with millimeter working range, Review of Scientific Instruments, Vol. 93, pp. 103703, Oct. 2022.
• Yohei Kono, Stephen A. Adam, Yuko Sato, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS, J Cell Biol, Vol. 221, No. 12, e202201024, Oct. 2022.
• Yancen Dai, Yuko Sato, Bo Zhu, Tetsuya Kitaguchi, Hiroshi Kimura, Farid J. Ghadess, Hiroshi Ueda. Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting, Chemical Science, The Royal Society of Chemistry, Vol. 13, Issue 33, p. 9739-9748, Aug. 2022.
• Ani Grigoryan, Johannes Pospiech, Stephen Krämer, Daniel Lipka, Thomas Liehr, Hartmut Geiger, Hiroshi Kimura, Medhanie A Mulaw, Maria Carolina Florian. Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells, Stem Cell Reports, Vol. 16, No. 4, pp. 708-716, Apr. 2022.
• Rang FJ, de Luca KL, de Vries SS, Valdes-Quezada C, Boele E, Nguyen PD, Guerreiro I, Sato Y, Kimura H, Bakkers J, Kind J. Single-cell profiling of transcriptome and histone modifications with EpiDamID, Mol Cell, Mar. 2022.
• Tadayoshi Murakawa, Tsuyoshi Nakamura, Kohei Kawaguchi, Futoshi Murayama, Ning Zhao, Timothy J. Stasevich, Hiroshi Kimura, Naonobu Fujita. A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body, Development, Vol. 149, No. 6, Mar. 2022.  公式リンク  
  
• Tadayoshi Murakawa, Tsuyoshi Nakamura, Kohei Kawaguchi, Futoshi Murayama, Ning Zhao, Timothy J. Stasevich, Hiroshi Kimura, Naonobu Fujita. A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body, Development, Vol. 149, No. 6, Mar. 2022.  公式リンク  
  
• Hiroshi Kimura, Yuko Sato. Imaging transcription elongation dynamics by new technologies unveils the organization of initiation and elongation in transcription factories, Current Opinion in Cell Biology, Volume 74, Page 71-79, Feb. 2022.
• Bartlett DA, Dileep V, Handa T, Ohkawa Y, Kimura H, Henikoff S. High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq), J Cell Biol, 220, 12, e202103078, Feb. 2022.
• Kimura, H., Sato, Y., Hiroshi Kimura. Imaging transcription elongation dynamics by new technologies unveils the organization of initiation and elongation in transcription factories, Current Opinion in Cell Biology, Vol. 74, pp. 71-79, 2022.  公式リンク  
  
• Tomimatsu, Kosuke, Bihary, Dora, Olan, Ioana, Parry, Aled J., Schoenfelder, Stefan, Chan, Adelyne S. L., Slater, Guy St. C., Ito, Yoko, Rugg-Gunn, Peter J., Kirschner, Kristina, Bermejo-Rodriguez, Camino, Seko, Tomomi, Kugoh, Hiroyuki, Shiraishi, Ken, Sayama, Koji, Kimura, Hiroshi, Fraser, Peter, Narita, Masako, Samarajiwa, Shamith A., Narita, Masashi, Hiroshi Kimura. Locus-specific induction of gene expression from heterochromatin loci during cellular senescence, Nature Aging, 2022.  公式リンク  
  
• Uchino, S., Ito, Y., Sato, Y., Handa, T., Ohkawa, Y., Tokunaga, M., Kimura, H., Hiroshi Kimura. Live imaging of transcription sites using an elongating RNA polymerase II–specific probe, Journal of Cell Biology, Vol. 221, No. 2, 2022.  公式リンク  
  
• Kamiya, Naoki, Kuramoto, Kazuki, Takishima, Kento, Yumoto, Tatsuya, Oda, Haruka, Shimi, Takeshi, Kimura, Hiroshi, Matsushita, Michio, Fujiyoshi, Satoru, Hiroshi Kimura. Superfluid helium nanoscope insert with millimeter working range, Review of Scientific Instruments, 2022.  公式リンク  
  
• Esquivel-Chavez, Alfredo, Maki, Takahisa, Tsubouchi, Hideo, Handa, Testuya, Kimura, Hiroshi, Haber, James E., Thon, Genevieve, Iwasaki, Hiroshi, Hiroshi Kimura. Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast Schizosaccharomyces pombe, Genes & Genetic Systems, 2022.  公式リンク  
  
• Yancen Dai, Yuko Sato, Bo Zhu, Tetsuya Kitaguchi, Hiroshi Kimura, Farid J. Ghadessy, Hiroshi Ueda. Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting, Chemical Science, 2022.  公式リンク  
  
• Kamiya, Naoki, Kuramoto, Kazuki, Takishima, Kento, Yumoto, Tatsuya, Oda, Haruka, Shimi, Takeshi, Kimura, Hiroshi, Matsushita, Michio, Fujiyoshi, Satoru, Hiroshi Kimura. Erratum: "Superfluid helium nanoscope insert with millimeter working range " [Vol 93, 103703 (2022)], Review of Scientific Instruments, 2022.  公式リンク  
  
• Hayashi-Takanaka Y, Hayashi Y, Hirano Y, Hiroshi Kimura. MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry, Nucleic Acids Research, 49, 21, 12152-12166, Dec. 2021.
• Harada A, Kimura H, Ohkawa Y. Recent advances in single-cell epigenomics, Curr Opin Struct Biol, 71, 116-122, Dec. 2021.
• Matsumura Y, Ito R, Yajima A, Yamaguchi R, Tanaka T, Kawamura T, Magoori K, Abe Y, Uchida A, Yoneshiro T, Hirakawa H, Zhang J, Arai M, Yang C, Yang G, Takahashi H, Fujihashi H, Nakaki R, Yamamoto S, Ota S, Tsutsumi S, Inoue SI, Hiroshi Kimura, Wada Y, Kodama T, Inagaki T, Osborne TF, Hiroyuki Aburatani, Node K, Sakai J. Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis, Nat Commun, 12, 1, 7045, Dec. 2021.
• Uchino S, Ito Y, Sato Y, Handa T, Ohkawa Y, Tokunaga M, Kimura H. Live imaging of transcription sites using an elongating RNA polymerase II-specific probe., J Cell Biol, Vol. 221, No. 2, p. e202104134 (23 pages), Dec. 2021.  公式リンク  
  
• Maehara K, Tomimatsu K, Harada A, Tanaka Kaori, Sato Shoko, Fukuoka M, Okada S, Handa T, Kurumizaka H, Saitoh N, Hiroshi Kimura, Ohkawa Y. Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections, Mol Syst Biol, 17, 11, e10323, Nov. 2021.
• Yuko Sato, Masaru Nakao, Hiroshi Kimura. Live-cell imaging probes to track chromatin modification dynamics, Microscopy (Oxf), Vol. 70, Issue 5, Page 415-422, Oct. 2021.
• Kudo H, Matsuo M, Satoh S, Hata T, Hachisu R, Nakamura M, Yamamoto YY, Kimura H, Matsui M, Obokata J. Cryptic promoter activation occurs by at least two different mechanisms in the Arabidopsis genome, Plant J, 108, 1, 29-39, Oct. 2021.
• Yang Liu, Ning Zhao, Masato T. Kanemaki, Yotaro Yamamoto, Yoshifusa Sadamura, Yuma Ito, Makio Tokunaga, Timothy J. Stasevich, Hiroshi Kimura. Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells, Genes Cells., Vol. 26, No. 11, p. 905-926, Sept. 2021.  公式リンク  
  
• Yuko Sato, Hiroshi Kimura. Multiplexed Imaging of Posttranslational Modifications of Endogenous Proteins in Live Cells, Methods in Molecular Biology, volume 2350, page 31-41, July 2021.
• Zhang J, Matsumura Y, Kano Y, Yoshida A, Kawamura T, Hirakawa H, Inagaki T, Tanaka Toshiya, Hiroshi Kimura, Yanagi S, Fukami K, Doi T, Osborne TF, Kodama T, Aburatani H, Sakai J. Ubiquitination-dependent and -independent repression of target genes by SETDB1 reveal a context-dependent role for its methyltransferase activity during adipogenesis, Genes Cells, 26, 7, 513-529, July 2021.
• Yuko Sato, Hiroshi Kimura. Dynamic Behavior of Inactive X Chromosome Territory During the Cell Cycle as Revealed by H3K27me3-Specific Intracellular Antibody, Methods in Molecular Biology, volume 1342, June 2021.
• Mio K. Shibuta, Takuya Sakamoto, Tamako Yamaoka, Mayu Yoshikawa, Shusuke Kasamatsu, Noriyoshi Yagi, Satoru Fujimoto, Takamasa Suzuki, Satoshi Uchino, Yuko Sato, Hiroshi Kimura, Sachihiro Matsunaga. A live imaging system to analyze spatiotemporal dynamics of RNA polymerase II modification in Arabidopsis thaliana, Communications Biology, Volume 4, May 2021.
• Muraoka Y, Nikaido A, Kowada R, Kimura H, Yamaguchi M, Yoshida H. Identification of Rpd3 as a novel epigenetic regulator of Drosophila FIG 4, a Charcot-Marie-Tooth disease-causing gene, Neuroreport, 32, 7, 562-568, May 2021.
• Tachiwana H, Dacher M, Maehara K, Harada A, Seto Y, Katayama R, Ohkawa Y, Kimura H, Kurumizaka H, Saitoh N. Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay., eLife, 10, e66290, May 2021.
• Forero-Quintero LS, Raymond W, Handa T, Saxton MN, Morisaki T, Kimura H, Bertrand E, Munsky B, Stasevich TJ. Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene, Nat Commun, 12, 1, 3158, May 2021.
• Yuki Ohmuro-Matsuyama, Tetsuya Kitaguchi, Hiroshi Kimura, Hiroshi Ueda. Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies, ACS Omega, American Chemical Society, vol. 6, Issue 15, p. 10039-10046, Apr. 2021.
• Uchino S, Ito Y, Sato Y, Handa T, Yasuyuki Ohkawa, Tokunaga M, Kimura H. Visualizing transcription sites in living cells using a genetically encoded probe specific for the elongating form of RNA polymerase II, bioRxiv, No. 2021.04.27, p. 441582, Apr. 2021.  公式リンク  
  
• M. Hieda, T. Matsumoto, M. Isobe, S. Kurono, K. Yuka, S. Kametaka, J. Y. Wang, Y. H. Chi, K. Kameda, H. Kimura, N. Matsuura, S. Matsuura. The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal, Sci Rep, Vol. 11, No. 1, pp. 5358, Mar. 2021.
• Lennart Hilbert, Yuko Sato, Ksenia Kuznetsova, Tommaso Bianucci, Hiroshi Kimura, Frank Jülicher, Alf Honigmann, Vasily Zaburdaev, Nadine L. Vastenhouw. Transcription organizes euchromatin via microphase separation, Nature Communications, volume 12, No. 1, pp. 1360, Mar. 2021.
• R. Sousa-Luﾃｭs, G. Dujardin, I. Zukher, H. Kimura, C. Weldon, M. Carmo-Fonseca, N. J. Proudfoot, T. Nojima. POINT technology illuminates the processing of polymerase-associated intact nascent transcripts, Mol Cell, Vol. 81, No. 9, pp. 1935-1950.e6, Mar. 2021.
• Sjoerd J D Tjalsma, Mayako Hori, Yuko Sato, Aurelie Bousard, Akito Ohi, Ana Cláudia Raposo, Julia Roensch, Agnes Le Saux, Jumpei Nogami, Kazumitsu Maehara, Tomoya Kujirai, Tetsuya Handa, Sandra Bagés-Arnal, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Simão Teixeira da Rocha, Jan J Żylicz, Hiroshi Kimura, Edith Heard. H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing, EMBO reports, volume 22, Issue 3, e51989, Mar. 2021.
• Keita Ishida, Kanta Naruse, Yuta Mizouchi, Yoshihiro Ogawa, Michio Matsushita, Takeshi Shimi, Hiroshi Kimura, Satoru Fujiyoshi. Variable immersion microscopy with a high numerical aperture, Opt Lett, Vol. 46, No. 4, pp. 856-859, Feb. 2021.
• C. H. Ho, Y. Takizawa, W. Kobayashi, Y. Arimura, H. Kimura, H. Kurumizaka. Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase, Life Sci Alliance, Vol. 4, No. 4, Feb. 2021.
• Yusuke Fujiwara, Yuki Yamanashi, Akiko Fujimura, Yuko Sato, Tomoya Kujirai, Hitoshi Kurumizaka, Hiroshi Kimura, Kenzo Yamatsugu, Shigehiro A. Kawashima, Motomu Kanai. Live-Cell Epigenome Manipulation by Synthetic Histone Acylation Catalyst System, Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 4, Jan. 2021.
• Tada, M., Hayashi, A., Asano, Y., Kubiura-Ichimaru, M., Ito, T., Yoshii, M., Kimura, H., Matsuda, Y., Oshimura, M., Hiroshi Kimura. Evidence for divergence of DNA methylation maintenance and a conserved inhibitory mechanism from DNA demethylation in chickens and mammals, Genes and Genomics, Vol. 43, No. 3, pp. 269-280, 2021.  公式リンク  
  
• Ohhata, T., Yamazawa, K., Miura-Kamio, A., Takahashi, S., Sakai, S., Tamura, Y., Uchida, C., Kitagawa, K., Niida, H., Hiratani, I., Kobayashi, H., Kimura, H., Wutz, A., Kitagawa, M., Hiroshi Kimura. Dynamics of transcription-mediated conversion from euchromatin to facultative heterochromatin at the Xist promoter by Tsix, Cell Reports, Vol. 34, No. 13, 2021.  公式リンク  
  
• Hilbert, L., Sato, Y., Kuznetsova, K., Bianucci, T., Kimura, H., Jülicher, F., Honigmann, A., Zaburdaev, V., Vastenhouw, N.L., Hiroshi Kimura. Author Correction: Transcription organizes euchromatin via microphase separation (Nature Communications, (2021), 12, 1, (1360), 10.1038/s41467-021-21589-3), Nature Communications, Vol. 12, No. 1, 2021.  公式リンク  
  
• T. Imada, T. Shimi, A. Kaiho, Y. Saeki, H. Kimura. RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cells, Genes Cells, Vol. 26, No. 5, pp. 298-312, Dec. 2020.
• I. Olan, A. J. Parry, S. Schoenfelder, M. Narita, Y. Ito, A. S. L. Chan, G. S. C. Slater, D. Bihary, M. Bando, K. Shirahige, H. Kimura, S. A. Samarajiwa, P. Fraser. Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence, Nat Commun, Vol. 11, No. 1, pp. 6049, Nov. 2020.
• Y. Sakamoto, M. Sato, Y. Sato, A. Harada, T. Suzuki, C. Goto, K. Tamura, K. Toyooka, H. Kimura, Y. Ohkawa, I. Hara-Nishimura, S. Takagi, S. Matsunaga. Subnuclear gene positioning through lamina association affects copper tolerance, Nat Commun, Vol. 11, No. 1, pp. 5914, Nov. 2020.
• D. T. Gruszka, S. Xie, H. Kimura, H. Yardimci. Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication, Sci Adv, Vol. 6, No. 38, Sept. 2020.
• Tetsuya Handa, Akihito Harada, Kazumitsu Maehara, Shoko Sato, Masaru Nakao, Naoki Goto, Hitoshi Kurumizaka, Yasuyuki Ohkawa, Hiroshi Kimura. Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input, Nat Protoc, Vol. 15, No. 10, pp. 3334-3360, Aug. 2020.
• K. Otake, J. I. Ohzeki, N. Shono, K. Kugou, K. Okazaki, T. Nagase, H. Yamakawa, N. Kouprina, V. Larionov, H. Kimura, W. C. Earnshaw, H. Masumoto. CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly, J Cell Sci, Vol. 133, No. 15, July 2020.
• N. M. C. Martins, F. Cisneros-Soberanis, E. Pesenti, N. Y. Kochanova, W. H. Shang, T. Hori, T. Nagase, H. Kimura, V. Larionov, H. Masumoto, T. Fukagawa, W. C. Earnshaw. H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory, J Cell Sci, Vol. 133, No. 14, June 2020.
• S. Golfier, T. Quail, H. Kimura, J. Bruguﾃｩs. Cohesin and condensin extrude DNA loops in a cell cycle-dependent manner, Elife, Vol. 9, May 2020.
• Y. Higashijima, Y. Matsui, T. Shimamura, R. Nakaki, N. Nagai, S. Tsutsumi, Y. Abe, V. M. Link, M. Osaka, M. Yoshida, R. Watanabe, T. Tanaka, A. Taguchi, M. Miura, X. Ruan, G. Li, T. Inoue, M. Nangaku, H. Kimura, T. Furukawa, H. Aburatani, Y. Wada, Y. Ruan, C. K. Glass, Y. Kanki. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells, Embo j, Vol. 39, No. 7, pp. e103949, Apr. 2020.
• N. A. Watson, T. N. Cartwright, C. Lawless, M. Cﾃ｡mara-Donoso, O. Sen, K. Sako, T. Hirota, H. Kimura, J. M. G. Higgins. Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites, Nat Commun, Vol. 11, No. 1, pp. 1684, Apr. 2020.
• H. Ideno, K. Nakashima, K. Komatsu, R. Araki, M. Abe, Y. Arai, H. Kimura, Y. Shinkai, M. Tachibana, A. Nifuji. G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development, Bone, Vol. 137, pp. 115332, Apr. 2020.
• Y. Hayashi-Takanaka, Y. Kina, F. Nakamura, L. E. Becking, Y. Nakao, T. Nagase, N. Nozaki, H. Kimura. Histone modification dynamics as revealed by multicolor immunofluorescence-based single-cell analysis, J Cell Sci, Vol. 133, No. 14, Jan. 2020.
• Ochiai, H., Hayashi, T., Umeda, M., Yoshimura, M., Harada, A., Shimizu, Y., Nakano, K., Saitoh, N., Liu, Z., Yamamoto, T., Okamura, T., Ohkawa, Y., Kimura, H., Nikaido, I., Hiroshi Kimura. Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells, Science Advances, Vol. 6, No. 25, 2020.  公式リンク  
  
• R. Nakato, Y. Wada, R. Nakaki, G. Nagae, Y. Katou, S. Tsutsumi, N. Nakajima, H. Fukuhara, A. Iguchi, T. Kohro, Y. Kanki, Y. Saito, M. Kobayashi, A. Izumi-Taguchi, N. Osato, K. Tatsuno, A. Kamio, Y. Hayashi-Takanaka, H. Wada, S. Ohta, M. Aikawa, H. Nakajima, M. Nakamura, R. C. McGee, K. W. Heppner, T. Kawakatsu, M. Genno, H. Yanase, H. Kume, T. Senbonmatsu, Y. Homma, S. Nishimura, T. Mitsuyama, H. Aburatani, H. Kimura, K. Shirahige. Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells, Epigenetics Chromatin, Vol. 12, No. 1, pp. 77, Dec. 2019.
• M. Dacher, H. Tachiwana, N. Horikoshi, T. Kujirai, H. Taguchi, H. Kimura, H. Kurumizaka. Incorporation and influence of Leishmania histone H3 in chromatin, Nucleic Acids Res, Vol. 47, No. 22, pp. 11637-11648, Nov. 2019.
• S. Nakamura, S. Hira, M. Fujiwara, N. Miyagata, T. Tsuji, A. Kondo, H. Kimura, Y. Shinozuka, M. Hayashi, S. Kobayashi, M. Mukai. A truncated form of a transcription factor Mamo activates vasa in Drosophila embryos, Commun Biol, Vol. 2, pp. 422, Nov. 2019.
• K. Suda, Y. Muraoka, A. Ortega-Yanez, H. Yoshida, F. Kizu, T. Hochin, H. Kimura, M. Yamaguchi. Reduction of Rpd3 suppresses defects in locomotive ability and neuronal morphology induced by the knockdown of Drosophila SLC25A46 via an epigenetic pathway, Exp Cell Res, Vol. 385, No. 2, pp. 111673, Oct. 2019.
• A. Karoutas, W. Szymanski, T. Rausch, S. Guhathakurta, E. A. Rog-Zielinska, R. Peyronnet, J. Seyfferth, H. R. Chen, R. de Leeuw, B. Herquel, H. Kimura, G. Mittler, P. Kohl, O. Medalia, J. O. Korbel, A. Akhtar. The NSL complex maintains nuclear architecture stability via lamin A/C acetylation, Nat Cell Biol, Vol. 21, No. 10, pp. 1248-1260, Oct. 2019.
• F. Ohka, K. Shinjo, S. Deguchi, Y. Matsui, Y. Okuno, K. Katsushima, M. Suzuki, A. Kato, N. Ogiso, A. Yamamichi, K. Aoki, H. Suzuki, S. Sato, N. Arul Rayan, S. Prabhakar, J. Goke, T. Shimamura, R. Maruyama, S. Takahashi, A. Suzumura, H. Kimura, T. Wakabayashi, H. Zong, A. Natsume, Y. Kondo. Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas, Cancer Res, Vol. 79, No. 19, pp. 4814-4827, Oct. 2019.
• Yuko Sato, Lennart Hilbert, Haruka Oda, Yinan Wan, John M. Heddleston, Teng-Leong Chew, Vasily Zaburdaev, Philipp Keller, Timothee Lionnet, Nadine Vastenhouw, Hiroshi Kimura. Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live cell analysis, Development, vol. 146, no. 19, Sept. 2019.
• Chenjiang Liu, Yoshihiro Kobashigawa, Soichiro Yamauchi, Yuya Toyota, Manaka Teramoto, Yuka Ikeguchi, Natsuki Fukuda, Takashi Sato, Yuko Sato, Hiroshi Kimura, Hiroshi Morioka. Preparation of single-chain Fv antibodies in the cytoplasm of Escherichia coli by simplified and systematic chaperone optimization, The Journal of Biochemistry,, Volume 166, Issue 6, Page 455-462, Sept. 2019.
• N. Horikoshi, T. Kujirai, K. Sato, H. Kimura, H. Kurumizaka. Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo, Biochem Biophys Res Commun, Vol. 515, No. 4, pp. 719-724, Aug. 2019.
• Chan-I Chung, Yuko Sato, Yuki Ohmuro-Matsuyama, Shinichi Machida, Hitoshi Kurumizaka, Hiroshi Kimura, Hiroshi Ueda. Intrabody-based FRET probe to visualize endogenous histone acetylation, Scientific Reports, Springer-Nature, Vol. 9, No. 1, pp. 10188, July 2019.  公式リンク  
  
• S. Yamauchi, Y. Kobashigawa, N. Fukuda, M. Teramoto, Y. Toyota, C. Liu, Y. Ikeguchi, T. Sato, Y. Sato, H. Kimura, T. Masuda, S. Ohtsuki, K. Noi, T. Ogura, H. Morioka. Cyclization of Single-Chain Fv Antibodies Markedly Suppressed Their Characteristic Aggregation Mediated by Inter-Chain VH-VL Interactions, Molecules, Vol. 24, No. 14, July 2019.
• N. Zhao, K. Kamijo, P. D. Fox, H. Oda, T. Morisaki, Y. Sato, H. Kimura, T. J. Stasevich. A genetically encoded probe for imaging nascent and mature HA-tagged proteins in vivo, Nat Commun, Vol. 10, No. 1, pp. 2947, July 2019.
• A. Murashima, K. Shinjo, K. Katsushima, T. Onuki, Y. Kondoh, H. Osada, N. Kagaya, K. Shin-Ya, H. Kimura, M. Yoshida, S. Murakami, Y. Kondo. Identification of a chemical modulator of EZH2-mediated silencing by cell-based high-throughput screening assay, J Biochem, Vol. 166, No. 1, pp. 41-50, July 2019.
• Y. Hayashi-Takanaka, Y. Kina, F. Nakamura, S. Yamazaki, M. Harata, Rwmv Soest, H. Kimura, Y. Nakao. Effect of mycalolides isolated from a marine sponge Mycale aff. nullarosette on actin in living cells, Sci Rep, Vol. 9, No. 1, pp. 7540, May 2019.
• Ryosuke Nagashima, Kayo Hibino, S.S. Ashwin, Michael Babokhov, Shin Fujishiro, Ryosuke Imai, Tadasu Nozaki, Sachiko Tamura, Tomomi Tani, Hiroshi Kimura, Michael Shribak, Masato T. Kanemaki, Masaki Sasai, Kazuhiro Maeshima. Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II, Journal of Cell Biology, Vol. 218, No. 5, pp. 1511–1530, Mar. 2019.
• K. Yamagata, K. Nagai, H. Miyamoto, M. Anzai, H. Kato, K. Miyamoto, S. Kurosaka, R. Azuma, II Kolodeznikov, A. V. Protopopov, V. V. Plotnikov, H. Kobayashi, R. Kawahara-Miki, T. Kono, M. Uchida, Y. Shibata, T. Handa, Y. Hosoi, T. Mitani, K. Matsumoto, A. Iritani, K. Yamagata, K. Nagai, H. Miyamoto, M. Anzai, H. Kato, K. Miyamoto, S. Kurosaka, R. Azuma, II Kolodeznikov, A. V. Protopopov, V. V. Plotnikov, H. Kobayashi, R. Kawahara-Miki, T. Kono, M. Uchida, Y. Shibata, T. Handa, H. Kimura, Y. Hosoi, T. Mitani, K. Matsumoto, A. Iritani. Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging, Sci Rep, Vol. 9, No. 1, pp. 4050, Mar. 2019.
• Y. Arimura, H. Tachiwana, H. Takagi, T. Hori, H. Kimura, T. Fukagawa, H. Kurumizaka. The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism, Nat Commun, Vol. 10, No. 1, pp. 576, Feb. 2019.
• T. Matsuda, T. Irie, S. Katsurabayashi, Y. Hayashi, T. Nagai, N. Hamazaki, A. M. D. Adefuin, F. Miura, T. Ito, H. Kimura, K. Shirahige, T. Takeda, K. Iwasaki, T. Imamura, K. Nakashima. Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion, Neuron, Vol. 101, No. 3, pp. 472-485.e7, Feb. 2019.
• A. K. Okita, F. Zafar, J. Su, D. Weerasekara, T. Kajitani, T. S. Takahashi, H. Kimura, Y. Murakami, H. Masukata, T. Nakagawa. Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription, Commun Biol, Vol. 2, no. 17, pp. 17, Jan. 2019.
• Takeshi Shimi, Hiroshi Kimura. A mosaic of old and young nucleoporins., J Cell Biol, Vol. 218, No. 2, pp. 385－386, Jan. 2019.
• Tetsuya Handa, Hiroshi Kimura. A chromatin integration labelling method enables epigenomic profiling with lower input, Nat Cell Biol, Vol. 21, No. 2, pp. 287－296, Dec. 2018.
• Y. Arimura, M. Ikura, R. Fujita, M. Noda, W. Kobayashi, N. Horikoshi, J. Sun, L. Shi, M. Kusakabe, M. Harata, Y. Ohkawa, S. Tashiro, H. Kimura, T. Ikura, H. Kurumizaka. Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome, Nucleic Acids Res, Vol. 46, No. 19, pp. 10007-10018, Nov. 2018.
• Yuko Sato, Timothy J. Stasevich, Hiroshi Kimura. Visualizing the Dynamics of Inactive X Chromosomes in Living Cells Using Antibody-Based Fluorescent Probes, Methods Mol Biol, Humana, New York, NY, Vol. 1861, pp. 91-102, Sept. 2018.
• Y. Azuma, H. Imai, Y. Kawaguchi, I. Nakase, H. Kimura, S. Futaki. Modular Redesign of a Cationic Lytic Peptide To Promote the Endosomal Escape of Biomacromolecules, Angew Chem Int Ed Engl, Vol. 57, No. 39, pp. 12771-12774, Sept. 2018.
• Lusy Handoko, Bogumil Kaczkowski, Chung-Chau Hon, Marina Lizio, Masatoshi Wakamori, Takayoshi Matsuda, Takuhiro Ito, Prashanti Jeyamohan, Yuko Sato, Kensaku Sakamoto, Shigeyuki Yokoyama, Hiroshi Kimura, Aki Minoda, Takashi Umehara. JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states, Epigenetics, Volume 13, Issue 4, Page 410-431, Aug. 2018.
• L. Handoko, B. Kaczkowski, C. C. Hon, M. Lizio, M. Wakamori, T. Matsuda, T. Ito, P. Jeyamohan, Y. Sato, K. Sakamoto, S. Yokoyama, H. Kimura, A. Minoda, T. Umehara. JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states, Epigenetics, Vol. 13, No. 4, pp. 410-431, Aug. 2018.
• M. R. Higgs, K. Sato, J. J. Reynolds, S. Begum, R. Bayley, A. Goula, A. Vernet, K. L. Paquin, D. G. Skalnik, W. Kobayashi, M. Takata, N. G. Howlett, H. Kurumizaka, H. Kimura, G. S. Stewart. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2, Mol Cell, Vol. 71, No. 1, pp. 25-41.e6, July 2018.
• E. Arai, F. Miura, Y. Totoki, S. Yamashita, Y. Tian, M. Gotoh, H. Ojima, H. Nakagawa, Y. Takahashi, H. Nakamura, N. Hama, M. Kato, H. Kimura, Y. Suzuki, T. Ito, T. Shibata, Y. Kanai. Epigenome mapping of human normal purified hepatocytes: personal epigenome variation and genome-epigenome correlation, Epigenomics, Vol. 10, No. 7, pp. 955-979, July 2018.
• A. Takeuchi, K. Iida, T. Tsubota, M. Hosokawa, M. Denawa, J. B. Brown, K. Ninomiya, M. Ito, H. Kimura, T. Abe, H. Kiyonari, K. Ohno, M. Hagiwara. Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain, Cell Rep, Vol. 23, No. 5, pp. 1326-1341, May 2018.
• A. J. Parry, M. Hoare, D. Bihary, R. Hansel-Hertsch, S. Smith, K. Tomimatsu, E. Mannion, A. Smith, P. D'Santos, I. A. Russell, S. Balasubramanian, H. Kimura, S. A. Samarajiwa, M. Narita. NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence, Nat Commun, Vol. 9, No. 1, pp. 1840, May 2018.
• Y. Abe, Y. Fujiwara, H. Takahashi, Y. Matsumura, T. Sawada, S. Jiang, R. Nakaki, A. Uchida, N. Nagao, M. Naito, S. Kajimura, H. Kimura, T. F. Osborne, H. Aburatani, T. Kodama, T. Inagaki, J. Sakai. Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch, Nat Commun, Vol. 9, No. 1, pp. 1566, Apr. 2018.
• S. Kuroki, Y. Nakai, R. Maeda, N. Okashita, M. Akiyoshi, Y. Yamaguchi, S. Kitano, H. Miyachi, R. Nakato, K. Ichiyanagi, K. Shirahige, H. Kimura, Y. Shinkai, M. Tachibana. Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis, Stem Cell Reports, Vol. 10, No. 4, pp. 1340-1354, Apr. 2018.
• Akihito Harada, Kazumitsu Maehara, Yusuke Ono, Hiroyuki Taguchi, Kiyoshi Yoshioka, Yasuo Kitajima, Yan Xie, Yuko Sato, Takeshi Iwasaki, Jumpei Nogami, Seiji Okada, Tetsuro Komatsu, Yuichiro Semba, Tatsuya Takemoto, Hiroshi Kimura, Hitoshi Kurumizaka, Yasuyuki Ohkawa. Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration, Nature Communications, vol. 9, Apr. 2018.
• J. G. Ruppert, K. Samejima, M. Platani, O. Molina, H. Kimura, A. A. Jeyaprakash, S. Ohta, W. C. Earnshaw. HP1alpha targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry, Embo j, Vol. 37, No. 6, Mar. 2018.
• C. Jenness, S. Giunta, M. M. Muller, H. Kimura, T. W. Muir, H. Funabiki. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome, Proceedings of the National Academy of Sciences of the United States of America, Jan. 2018.
• C. C. L. Chen, P. Goyal, M. M. Karimi, M. H. Abildgaard, H. Kimura, M. C. Lorincz. H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2, Genome Res, Vol. 28, No. 1, pp. 37-51, Jan. 2018.
• K. Shiraishi, A. Shindo, A. Harada, H. Kurumizaka, H. Kimura, Y. Ohkawa, H. Matsuyama. Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders, Andrology, Vol. 6, No. 1, pp. 158-165, 2018.
• T. Kajitani, H. Kato, Y. Chikashige, C. Tsutsumi, Y. Hiraoka, H. Kimura, Y. Ohkawa, C. Obuse, D. Hermand, Y. Murakami. Ser7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAi, Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 52, pp. E11208-e11217, Dec. 2017.
• L. Imre, Z. Simandi, A. Horvath, G. Fenyofalvi, P. Nanasi, E. F. Niaki, E. Hegedus, Z. Bacso, U. Weyemi, R. Mauser, J. Ausio, A. Jeltsch, W. Bonner, L. Nagy, H. Kimura, G. Szabo. Nucleosome stability measured in situ by automated quantitative imaging, Scientific reports, Vol. 7, No. 1, pp. 12734, Oct. 2017.
• A. Shirai, T. Kawaguchi, H. Shimojo, D. Muramatsu, M. Ishida-Yonetani, Y. Nishimura, H. Kimura, J. I. Nakayama, Y. Shinkai. Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly, eLife, Vol. 6, Aug. 2017.
• T. Kamiunten, H. Ideno, A. Shimada, Y. Arai, T. Terashima, Y. Tomooka, Y. Nakamura, K. Nakashima, H. Kimura, Y. Shinkai, M. Tachibana, A. Nifuji. Essential roles of G9a in cell proliferation and differentiation during tooth development, Experimental cell research, Vol. 357, No. 2, pp. 202-210, Aug. 2017.
• P. N. T. An, K. Shimaji, R. Tanaka, H. Yoshida, H. Kimura, E. Fukusaki, M. Yamaguchi. Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a, Scientific reports, Vol. 7, No. 1, pp. 7343, Aug. 2017.
• S. Y. Isobe, K. Nagao, N. Nozaki, H. Kimura, C. Obuse. Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair, Cell reports, Vol. 20, No. 2, pp. 297-307, July 2017.
• R. Arai, T. Sugawara, Y. Minakuchi, Yuko Sato, A. Toyoda, K. Nabeshima, H. Kimura, A. Kimura. Reduction in chromosome mobility accompanies nuclear organization during early embryogenesis in Caenorhabditis elegans, Scientific reports, Vol. 7, No. 1, pp. 3631, June 2017.
• T. Yamazaki, Y. Hatano, T. Handa, S. Kato, K. Hoida, R. Yamamura, T. Fukuyama, T. Uematsu, N. Kobayashi, H. Kimura, K. Yamagata. Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase, PloS one, Vol. 12, No. 5, pp. e0177764, May 2017.
• Yuko Sato, Hiroshi Kimura. Semi-quantitative Analysis of H4K20me1 Levels in Living Cells Using Mintbody, bio-protocol, vol. 7, no. 10, May 2017.
• K. Kurita, T. Sakamoto, N. Yagi, Y. Sakamoto, A. Ito, N. Nishino, K. Sako, M. Yoshida, H. Kimura, M. Seki, S. Matsunaga. Live imaging of H3K9 acetylation in plant cells, Scientific reports, Vol. 7, pp. 45894, Apr. 2017.
• H. Taguchi, Y. Xie, N. Horikoshi, K. Maehara, A. Harada, J. Nogami, K. Sato, Y. Arimura, A. Osakabe, T. Kujirai, T. Iwasaki, Y. Semba, T. Tachibana, H. Kimura, Y. Ohkawa, H. Kurumizaka. Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8, Biochemistry, Vol. 56, No. 16, pp. 2184-2196, Apr. 2017.
• M. Partolina, H. C. Thoms, K. G. MacLeod, G. Rodriguez-Blanco, M. N. Clarke, A. V. Venkatasubramani, R. Beesoo, V. Larionov, V. S. Neergheen-Bhujun, B. Serrels, H. Kimura, N. O. Carragher, A. Kagansky. Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array, Cell death discovery, Vol. 3, pp. 16077, Mar. 2017.
• J. Ueda, A. Harada, T. Urahama, S. Machida, K. Maehara, M. Hada, Y. Makino, J. Nogami, N. Horikoshi, A. Osakabe, H. Taguchi, H. Tanaka, H. Tachiwana, T. Yao, M. Yamada, T. Iwamoto, A. Isotani, M. Ikawa, T. Tachibana, Y. Okada, H. Kimura, Y. Ohkawa, H. Kurumizaka, K. Yamagata. Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis, Cell reports, Vol. 18, No. 3, pp. 593-600, 2017.
• Y. Shishido, T. Baba, T. Sato, Y. Shima, K. Miyabayashi, M. Inoue, H. Akiyama, H. Kimura, Y. Kanai, Y. Ishihara, S. Haraguchi, A. Miyazaki, D. Rozman, T. Yamazaki, M. H. Choi, Y. Ohkawa, M. Suyama, K. I. Morohashi. Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells, Scientific reports, Vol. 7, pp. 41912, 2017.
• T. Shiomi, A. Muto, S. Hozumi, H. Kimura, Y. Kikuchi. Histone H3 Lysine 27 Trimethylation Leads to Loss of Mesendodermal Competence During Gastrulation in Zebrafish Ectodermal Cells, Zoological science, Vol. 34, No. 1, pp. 64-71, 2017.
• E. Kakumu, S. Nakanishi, H. M. Shiratori, A. Kato, W. Kobayashi, S. Machida, T. Yasuda, N. Adachi, N. Saito, T. Ikura, H. Kurumizaka, H. Kimura, M. Yokoi, W. Sakai, K. Sugasawa. Xeroderma pigmentosum group C protein interacts with histones: regulation by acetylated states of histone H3, Genes to cells : devoted to molecular & cellular mechanisms, 2017.
• Y. Sato, T. Kujirai, R. Arai, H. Asakawa, C. Ohtsuki, N. Horikoshi, K. Yamagata, J. Ueda, T. Nagase, T. Haraguchi, Y. Hiraoka, A. Kimura, H. Kurumizaka, H. Kimura. A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation, J Mol Biol, Vol. 428, No. 20, pp. 3885-3902, Oct. 2016.
• Yuki Kuniyoshi, Kazumitsu Maehara, Takeshi Iwasaki, Masayasu Hayashi, Yuichiro Semba, Masatoshi Fujita, Yuko Sato, Hiroshi Kimura, Akihito Harada, Yasuyuki Ohkawa. Identification of immunoglobulin gene sequences from a small read number of mRNA-seq using hybridomas, PLOS ONE, vol. 11, no. 10, Oct. 2016.
• S. Koide, M. Oshima, K. Takubo, S. Yamazaki, E. Nitta, A. Saraya, K. Aoyama, Y. Kato, S. Miyagi, Y. Nakajima-Takagi, T. Chiba, H. Matsui, F. Arai, Y. Suzuki, H. Kimura, H. Nakauchi, T. Suda, Y. Shinkai, A. Iwama. Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes, Blood, Vol. 128, No. 5, pp. 638-49, 2016.
• Y. Kang, J. Wang, A. Neff, S. Kratzer, H. Kimura, R. E. Davis. Differential Chromosomal Localization of Centromeric Histone CENP-A Contributes to Nematode Programmed DNA Elimination, Cell reports, 2016.
• T. Kujirai, N. Horikoshi, K. Sato, K. Maehara, S. Machida, A. Osakabe, H. Kimura, Y. Ohkawa, H. Kurumizaka. Structure and function of human histone H3.Y nucleosome, Nucleic acids research, Vol. 44, No. 13, pp. 6127-41, 2016.
• J. Ohzeki, N. Shono, K. Otake, N. M. Martins, K. Kugou, H. Kimura, T. Nagase, V. Larionov, W. C. Earnshaw, H. Masumoto. KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation, Developmental cell, Vol. 37, No. 5, pp. 413-27, 2016.
• K. Shimaji, T. Konishi, H. Yoshida, H. Kimura, M. Yamaguchi. Genome-wide genetic screen identified the link between dG9a and epidermal growth factor receptor signaling pathway in vivo, Experimental cell research, Vol. 346, No. 1, pp. 53-64, 2016.
• M. Suzuki, C. Takagi, S. Miura, Y. Sakane, T. Sakuma, N. Sakamoto, T. Endo, Y. Kamei, Y. Sato, H. Kimura, T. Yamamoto, N. Ueno, K. T. Suzuki. In vivo tracking of histone H3 lysine 9 acetylation in Xenopus laevis during tail regeneration, Genes Cells, Vol. 21, No. 4, pp. 358-69, 2016.  公式リンク  
  
• S. Suzuki, H. Kato, Y. Suzuki, Y. Chikashige, Y. Hiraoka, H. Kimura, K. Nagao, C. Obuse, S. Takahata, Y. Murakami. Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast, Nucleic acids research, Vol. 44, No. 9, pp. 4147-62, 2016.
• R. Hansel-Hertsch, D. Beraldi, S. V. Lensing, G. Marsico, K. Zyner, A. Parry, M. Di Antonio, J. Pike, H. Kimura, M. Narita, D. Tannahill, S. Balasubramanian. G-quadruplex structures mark human regulatory chromatin, Nature genetics, 2016.
• D. Muramatsu, H. Kimura, K. Kotoshiba, M. Tachibana, Y. Shinkai. Pericentric H3K9me3 Formation by HP1 Interaction-defective Histone Methyltransferase Suv39h1, Cell structure and function, Vol. 41, No. 2, pp. 145-152, 2016.
• W. H. Shang, T. Hori, F. G. Westhorpe, K. M. Godek, A. Toyoda, S. Misu, N. Monma, K. Ikeo, C. W. Carroll, Y. Takami, A. Fujiyama, H. Kimura, A. F. Straight, T. Fukagawa. Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres, Nature communications, Vol. 7, pp. 13465, 2016.
• T. Urahama, A. Harada, K. Maehara, N. Horikoshi, K. Sato, Y. Sato, K. Shiraishi, N. Sugino, A. Osakabe, H. Tachiwana, W. Kagawa, H. Kimura, Y. Ohkawa, H. Kurumizaka. Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis, Epigenetics Chromatin, Vol. 9, pp. 2, 2016.
• M. Oka, S. Mura, K. Yamada, P. Sangel, S. Hirata, K. Maehara, K. Kawakami, T. Tachibana, Y. Ohkawa, H. Kimura, Y. Yoneda. Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes, Elife, Vol. 5, pp. e09540, 2016.
• E. Nakajima, K. Shimaji, T. Umegawachi, S. Tomida, H. Yoshida, N. Yoshimoto, S. Izawa, H. Kimura, M. Yamaguchi. The Histone Deacetylase Gene Rpd3 Is Required for Starvation Stress Resistance, PloS one, Vol. 11, No. 12, pp. e0167554, 2016.
• N. M. Martins, J. H. Bergmann, N. Shono, H. Kimura, V. Larionov, H. Masumoto, W. C. Earnshaw. Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3, Molecular biology of the cell, Vol. 27, No. 1, pp. 177-96, 2016.
• J. Y. Kaimori, K. Maehara, Y. Hayashi-Takanaka, A. Harada, M. Fukuda, S. Yamamoto, N. Ichimaru, T. Umehara, S. Yokoyama, R. Matsuda, T. Ikura, K. Nagao, C. Obuse, N. Nozaki, S. Takahara, T. Takao, Y. Ohkawa, H. Kimura, Y. Isaka. Histone H4 lysine 20 acetylation is associated with gene repression in human cells, Sci Rep, Vol. 6, pp. 24318, 2016.
• K. Katsushima, A. Natsume, F. Ohka, K. Shinjo, A. Hatanaka, N. Ichimura, S. Sato, S. Takahashi, H. Kimura, Y. Totoki, T. Shibata, M. Naito, H. J. Kim, K. Miyata, K. Kataoka, Y. Kondo. Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment, Nat Commun, Vol. 7, pp. 13616, 2016.
• M. Goto, N. Toda, K. Shimaji, D. N. Suong, N. Vo, H. Kimura, H. Yoshida, Y. H. Inoue, M. Yamaguchi. Polycomb-dependent nucleolus localization of Jumonji/Jarid2 during, Spermatogenesis, Vol. 6, No. 3, pp. e1232023, 2016.  公式リンク  
  
• Stunnenberg, H.G., Abrignani, S., Adams, D., de Almeida, M., Altucci, L., Amin, V., Amit, I., Antonarakis, S.E., Aparicio, S., Arima, T., Arrigoni, L., Arts, R., Asnafi, V., Badosa, M.E., Bae, J.-B., Bassler, K., Beck, S., Berkman, B., Bernstein, B.E., Bilenky, M., Bird, A., Bock, C., Boehm, B., Bourque, G., Breeze, C.E., Brors, B., Bujold, D., Burren, O., Bussemakers, M.J., Butterworth, A., Campo, E., Carrillo-de-Santa-Pau, E., Chadwick, L., Chan, K.M., Chen, W., Cheung, T.H., Chiapperino, L., Choi, N.H., Chung, H.-R., Clarke, L., Connors, J.M., Cronet, P., Danesh, J., Dermitzakis, M., Drewes, G., Durek, P., Dyke, S., Dylag, T., Eaves, C.J., Ebert, P., Eils, R., Eils, J., Ennis, C.A., Enver, T., Feingold, E.A., Felder, B., Ferguson-Smith, A., Fitzgibbon, J., Flicek, P., Foo, R.S.-Y., Fraser, P., Frontini, M., Furlong, E., Gakkhar, S., Gasparoni, N., Gasparoni, G., Geschwind, D.H., Glažar, P., Graf, T., Grosveld, F., Guan, X.-Y., Guigo, R., Gut, I.G., Hamann, A., Han, B.-G., Harris, R.A., Heath, S., Helin, K., Hengstler, J.G., Heravi-Moussavi, A., Herrup, K., Hill, S., Hilton, J.A., Hitz, B.C., Horsthemke, B., Hu, M., Hwang, J.-Y., Ip, N.Y., Ito, T., Javierre, B.-M., Jenko, S., Jenuwein, T., Joly, Y., Jones, S.J.M., Kanai, Y., Kang, H.G., Karsan, A., Kiemer, A.K., Kim, S.C., Kim, B.-J., Kim, H.-H., Kimura, H., Kinkley, S., Klironomos, F., Koh, I.-U., Kostadima, M., Kressler, C., Kreuzhuber, R., Kundaje, A., Küppers, R., Larabell, C., Lasko, P., Lathrop, M., Lee, D.H.S., Lee, S., Lehrach, H., Leitão, E., Lengauer, T., Lernmark, Å., Leslie, R.D., Leung, G.K.K., Leung, D., Loeffler, M., Ma, Y., Mai, A., Manke, T., Marcotte, E.R., Marra, M.A., Martens, J.H.A., Martin-Subero, J.I., Maschke, K., Merten, C., Milosavljevic, A., Minucci, S., Mitsuyama, T., Moore, R.A., Müller, F., Mungall, A.J., Netea, M.G., Nordström, K., Norstedt, I., Okae, H., Onuchic, V., Ouellette, F., Ouwehand, W., Pagani, M., Pancaldi, V., Pap, T., Pastinen, T., Patel, R., Paul, D.S., Pazin, M.J., Pelicci, P.G., Phillips, A.G., Polansky, J., Porse, B., Pospisilik, J.A., Prabhakar, S., Procaccini, D.C., Radbruch, A., Rajewsky, N., Rakyan, V., Reik, W., Ren, B., Richardson, D., Richter, A., Rico, D., Roberts, D.J., Rosenstiel, P., Rothstein, M., Salhab, A., Sasaki, H., Satterlee, J.S., Sauer, S., Schacht, C., Schmidt, F., Schmitz, G., Schreiber, S., Schröder, C., Schübeler, D., Schultze, J.L., Schulyer, R.P., Schulz, M., Seifert, M., Shirahige, K., Siebert, R., Sierocinski, T., Siminoff, L., Sinha, A., Soranzo, N., Spicuglia, S., Spivakov, M., Steidl, C., Strattan, J.S., Stratton, M., Südbeck, P., Sun, H., Suzuki, N., Suzuki, Y., Tanay, A., Torrents, D., Tyson, F.L., Ulas, T., Ullrich, S., Ushijima, T., Valencia, A., Vellenga, E., Vingron, M., Wallace, C., Wallner, S., Walter, J., Wang, H., Weber, S., Weiler, N., Weller, A., Weng, A., Wilder, S., Wiseman, S.M., Wu, A.R., Wu, Z., Xiong, J., Yamashita, Y., Yang, X., Yap, D.Y., Yip, K.Y., Yip, S., Yoo, J.-I., Zerbino, D., Zipprich, G., Hirst, M., Hiroshi Kimura. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery, Cell, Vol. 167, No. 5, pp. 1145-1149, 2016.  公式リンク  
  
• Yuko Sato, M. Mukai, H. Kimura. Histone Acetylation on Drosophila Polytene Chromosomes Visualized by Mintbody, Cytologia, vol. 80, no. 4, pp. 383-384, Dec. 2015.  公式リンク  
  
• Kazumitsu Maehara, Akihito Harada, Yuko Sato, Masaki Matsumoto, Keiichi I. Nakayama, Hiroshi Kimura, Yasuyuki Ohkawa. Tissue-specific expression of histone H3 variants diversified after species separation, Epigenetics & Chromatin, vol. 8, Sept. 2015.
• Akihito Harada, Kazumitsu Maehara, Yuko Sato, Daijiro Konno, Taro Tachibana, Hiroshi Kimura, Yasuyuki Ohkawa. Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle, Nucleic Acids Research, vol. 43, no. 2, pp. 775-786, Jan. 2015.
• K. Ruan, T. G. Yamamoto, H. Asakawa, Y. Chikashige, H. Kimura, H. Masukata, T. Haraguchi, Y. Hiraoka. Histone H4 acetylation required for chromatin decompaction during DNA replication, Scientific reports, Vol. 5, pp. 12720, 2015.
• K. Shimaji, T. Konishi, S. Tanaka, H. Yoshida, Y. Kato, Y. Ohkawa, T. Sato, M. Suyama, H. Kimura, M. Yamaguchi. Genomewide identification of target genes of histone methyltransferase dG9a during Drosophila embryogenesis, Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, No. 11, pp. 902-14, 2015.
• Y. Shinchi, M. Hieda, Y. Nishioka, A. Matsumoto, Y. Yokoyama, H. Kimura, S. Matsuura, N. Matsuura. SUV420H2 suppresses breast cancer cell invasion through down regulation of the SH2 domain-containing focal adhesion protein tensin-3, Experimental cell research, Vol. 334, No. 1, pp. 90-9, 2015.
• N. Shono, J. Ohzeki, K. Otake, N. M. Martins, T. Nagase, H. Kimura, V. Larionov, W. C. Earnshaw, H. Masumoto. CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly, Journal of cell science, Vol. 128, No. 24, pp. 4572-87, 2015.
• S. Wada, H. Ideno, A. Shimada, T. Kamiunten, Y. Nakamura, K. Nakashima, H. Kimura, Y. Shinkai, M. Tachibana, A. Nifuji. H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro, Histochemistry and cell biology, Vol. 144, No. 1, pp. 13-20, 2015.
• K. Wagatsuma, S. Tani-ichi, B. Liang, S. Shitara, K. Ishihara, M. Abe, H. Miyachi, S. Kitano, T. Hara, M. Nanno, H. Ishikawa, K. Sakimura, M. Nakao, H. Kimura, K. Ikuta. STAT5 Orchestrates Local Epigenetic Changes for Chromatin Accessibility and Rearrangements by Direct Binding to the TCRgamma Locus, Journal of immunology (Baltimore, Md. : 1950), Vol. 195, No. 4, pp. 1804-14, 2015.
• W. Yoshida, J. Tomikawa, M. Inaki, H. Kimura, M. Onodera, K. Hata, K. Nakabayashi. An insulator element located at the cyclin B1 interacting protein 1 gene locus is highly conserved among mammalian species, PloS one, Vol. 10, No. 6, pp. e0131204, 2015.
• Y. Abe, R. Rozqie, Y. Matsumura, T. Kawamura, R. Nakaki, Y. Tsurutani, K. Tanimura-Inagaki, A. Shiono, K. Magoori, K. Nakamura, S. Ogi, S. Kajimura, H. Kimura, T. Tanaka. JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis, Vol. 6, pp. 7052, 2015.
• J. D. Dias, T. Rito, E. Torlai Triglia, A. Kukalev, C. Ferrai, M. Chotalia, E. Brookes, H. Kimura, A. Pombo. Methylation of RNA polymerase 竇｡ non-cosensus Lysine residues marks early mammalian cells, eLife, Vol. 4, 2015.
• A. Harada, K. Maehara, Y. Sato, D. Konno, T. Tachibana, H. Kimura, Y. Ohkawa. Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle, Nucleic acids research, Vol. 43, No. 2, pp. 775-86, 2015.
• Y. Hayashi-Takanaka, K. Maehara, A. Harada, T. Umehara, S. Yokoyama, C. Obuse, Y. Ohkawa, N. Nozaki, H. Kimura. Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies, Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 23, No. 4, pp. 753-66, 2015.
• D. Iwamoto, K. Yamagata, M. Kishi, Y. Hayashi-Takanaka, H. Kimura, T. Wakayama, K. Saeki. Early development of cloned bovine embryos produced from oocytes enucleated by fluorescence metaphase II imaging using a conventional halogen-lamp microscope, Cellular reprogramming, Vol. 17, No. 2, pp. 106-14, 2015.
• T. Kamiunten, H. Ideno, A. Shimada, Y. Nakamura, H. Kimura, K. Nakashima, A. Nifuji. Coordinated expression of H3K9 histone methyltransferases during tooth development in mice, Histochemistry and cell biology, Vol. 143, No. 3, pp. 259-66, 2015.
• H. Kimura, Y. Hayashi-Takanaka, T. J. Stasevich, Y. Sato. Visualizing posttranslational and epigenetic modifications of endogenous proteins in vivo, Histochemistry and cell biology, Vol. 144, No. 2, pp. 101-9, 2015.
• K. Kirschner, S. A. Samarajiwa, J. M. Cairns, S. Menon, P. A. Perez-Mancera, K. Tomimatsu, C. Bermejo-Rodriguez, Y. Ito, T. Chandra, M. Narita, S. K. Lyons, A. G. Lynch, H. Kimura, T. Ohbayashi, S. Tavare. Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53, PLoS genetics, Vol. 11, No. 3, pp. e1005053, 2015.
• K. Kurimoto, Y. Yabuta, K. Hayashi, H. Ohta, H. Kiyonari, T. Mitani, Y. Moritoki, K. Kohri, H. Kimura, T. Yamamoto, Y. Katou, K. Shirahige, M. Saitou. Quantitative Dynamics of Chromatin Remodeling during Germ Cell Specification from Mouse Embryonic Stem Cells, Cell stem cell, Vol. 16, No. 5, pp. 517-32, 2015.
• K. Maehara, A. Harada, Y. Sato, M. Matsumoto, K. I. Nakayama, H. Kimura, Y. Ohkawa. Tissue-specific expression of histone H3 variants diversified after species separation, Epigenetics & chromatin, Vol. 8, pp. 35, 2015.
• A. Matsuda, Y. Chikashige, D. Q. Ding, C. Ohtsuki, C. Mori, H. Asakawa, H. Kimura, T. Haraguchi, Y. Hiraoka. Highly condensed chromatins are formed adjacent to subtelomeric and decondensed silent chromatin in fission yeast, Nature communications, Vol. 6, pp. 7753, 2015.
• Y. Matsumura, R. Nakaki, T. Inagaki, A. Yoshida, Y. Kano, H. Kimura, T. Tanaka, S. Tsutsumi, M. Nakao, T. Doi, K. Fukami, T. F. Osborne, T. Kodama, H. Aburatani, J. Sakai. H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation, Molecular cell, Vol. 60, No. 4, pp. 584-96, 2015.
• M. Mukai, S. Hira, K. Nakamura, S. Nakamura, H. Kimura, M. Sato, S. Kobayashi. H3K36 Trimethylation-Mediated Epigenetic Regulation is Activated by Bam and Promotes Germ Cell Differentiation During Early Oogenesis in Drosophila, Biology open, Vol. 4, No. 2, pp. 119-24, 2015.
• T. Nojima, T. Gomes, A. R. Grosso, H. Kimura, M. J. Dye, S. Dhir, M. Carmo-Fonseca, N. J. Proudfoot. Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing, Cell, Vol. 161, No. 3, pp. 526-40, 2015.
• L. M. Rapkin, K. Ahmed, S. Dulev, R. Li, H. Kimura, A. M. Ishov, D. P. Bazett-Jones. The histone chaperone DAXX maintains the structural organization of heterochromatin domains, Epigenetics & chromatin, Vol. 8, pp. 44, 2015.
• Timothy J. Stasevich, Yoko Hayashi-Takanaka, Yuko Sato, Kazumitsu Maehara, Yasuyuki Ohkawa, Kumiko Sakata-Sogawa, Makio Tokunaga, Takahiro Nagase, Naohito Nozaki, James G. McNally, Hiroshi Kimura. Regulation of RNA polymerase II activation by histone acetylation in single living cells, Nature, vol. 516, No. 7530, pp. 272-275, Dec. 2014.
• Timothy J Stasevich, Yuko Sato, Naohito Nozaki, Hiroshi Kimura. Quantifying histone and RNA polymerase II post-translational modification dynamics in mother and daughter cells, Methods, vol. 70, no. 2-3, pp. 77-78, Dec. 2014.
• Jun Ueda, Kazumitsu Maehara, Daisuke Mashiko, Takako Ichinose, Tatsuma Yao, Mayuko Hori, Yuko Sato, Hiroshi Kimura, Yasuyuki Ohkawa, Kazuo Yamagata. Heterochromatin Dynamics during the Differentiation Process Revealed by the DNA Methylation Reporter Mouse, MethylRO, Stem Cell Reports, vol. 2, no. 6, pp. 910-924, June 2014.
• T. Baba, H. Otake, T. Sato, K. Miyabayashi, Y. Shishido, C. Y. Wang, Y. Shima, H. Kimura, M. Yagi, Y. Ishihara, S. Hino, H. Ogawa, M. Nakao, T. Yamazaki, D. Kang, Y. Ohkawa, M. Suyama, B. C. Chung, K. Morohashi. Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1, Nature communications, Vol. 5, pp. 3634, 2014.
• Ideno H, Shimada A, Shimada A, Nakamura Y, Shimada A, Kimura H, Shimada A, Araki R, Shimada A, Abe M, Shimada A, Nakashima K, Shimada A, Nifuji A, Shimada A. Search for conditions to detect epigenetic marks and nuclear proteins in immunostaining of the testis and cartilage., J Histology 2014, pp. pp658293, 2014.
• Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y., Yamagata, K., Hiroshi Kimura. Erratum: Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO (Stem Cell Reports (2014) 2 (910-924)), Stem Cell Reports, Vol. 3, No. 1, pp. 216, 2014.  公式リンク  
  
• C. Zierhut, C. Jenness, H. Kimura, H. Funabiki. Nucleosomal regulation of chromatin composition and nuclear assembly revealed by histone depletion, Nature structural & molecular biology, Vol. 21, No. 7, pp. 617-25, 2014.
• Y. Yokoyama, A. Matsumoto, M. Hieda, Y. Shinchi, E. Ogihara, M. Hamada, Y. Nishioka, H. Kimura, K. Yoshidome, M. Tsujimoto, N. Matsuura. Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity, Breast cancer research : BCR, Vol. 16, No. 3, pp. R66, 2014.
• J. Ueda, K. Maehara, D. Mashiko, T. Ichinose, T. Yao, M. Hori, Y. Sato, H. Kimura, Y. Ohkawa, K. Yamagata. Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO, Stem cell reports, Vol. 2, No. 6, pp. 910-24, 2014.
• T. J. Stasevich, Y. Sato, N. Nozaki, H. Kimura. Quantifying histone and RNA polymerase II post-translational modification dynamics in mother and daughter cells, Methods (San Diego, Calif.), Vol. 70, No. 2-3, pp. 77-88, 2014.
• C. Song, Y. Feodorova, J. Guy, L. Peichl, K. L. Jost, H. Kimura, M. C. Cardoso, A. Bird, H. Leonhardt, B. Joffe, I. Solovei. DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution, Epigenetics & chromatin, Vol. 7, pp. 17, 2014.
• A. Onoda, O. Hosoya, K. Sano, K. Kiyama, H. Kimura, S. Kawano, R. Furuta, M. Miyaji, K. Tsutsui, K. M. Tsutsui. Nuclear dynamics of topoisomerase IIbeta reflects its catalytic activity that is regulated by binding of RNA to the C-terminal domain, Nucleic acids research, Vol. 42, No. 14, pp. 9005-20, 2014.
• T. Nakayama, K. Mihara, J. Kawata, H. Kimura, H. Saitoh. Adhesion of suspension cells on a coverslip in serum-free conditions, Analytical biochemistry, Vol. 466, pp. 1-3, 2014.
• T. Maejima, T. Inoue, Y. Kanki, T. Kohro, G. Li, Y. Ohta, H. Kimura, M. Kobayashi, A. Taguchi, S. Tsutsumi, H. Iwanari, S. Yamamoto, H. Aruga, S. Dong, J. F. Stevens, H. M. Poh, K. Yamamoto, T. Kawamura, I. Mimura, J. Suehiro, A. Sugiyama, K. Kaneki, H. Shibata, Y. Yoshinaka, T. Doi, A. Asanuma, S. Tanabe, T. Tanaka, T. Minami, T. Hamakubo, J. Sakai, N. Nozaki, H. Aburatani, M. Nangaku, X. Ruan, H. Tanabe, Y. Ruan, S. Ihara, A. Endo, T. Kodama, Y. Wada. Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells, PloS one, Vol. 9, No. 5, pp. e96005, 2014.
• J. Jullien, K. Miyamoto, V. Pasque, G. E. Allen, C. R. Bradshaw, N. J. Garrett, R. P. Halley-Stott, H. Kimura, K. Ohsumi, J. B. Gurdon. Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming, Molecular cell, Vol. 55, No. 4, pp. 524-36, 2014.
• T. Hori, W. H. Shang, A. Toyoda, S. Misu, N. Monma, K. Ikeo, O. Molina, G. Vargiu, A. Fujiyama, H. Kimura, W. C. Earnshaw, T. Fukagawa. Histone H4 Lys 20 monomethylation of the CENP-A nucleosome is essential for kinetochore assembly, Developmental cell, Vol. 29, No. 6, pp. 740-9, 2014.
• T. Hirose, G. Virnicchi, A. Tanigawa, T. Naganuma, R. Li, H. Kimura, T. Yokoi, S. Nakagawa, M. Benard, A. H. Fox, G. Pierron. NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies, Molecular biology of the cell, Vol. 25, No. 1, pp. 169-83, 2014.
• Y. Hayashi-Takanaka, T. J. Stasevich, H. Kurumizaka, N. Nozaki, H. Kimura. Evaluation of chemical fluorescent dyes as a protein conjugation partner for live cell imaging, PloS one, Vol. 9, No. 9, pp. e106271, 2014.
• A. Hayashi, N. Yamauchi, J. Shibahara, H. Kimura, T. Morikawa, S. Ishikawa, G. Nagae, A. Nishi, Y. Sakamoto, N. Kokudo, H. Aburatani, M. Fukayama. Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior, PloS one, Vol. 9, No. 3, pp. e91330, 2014.
• Yasuhiro Arimura, Hiroshi Kimura, Takashi Oda, Koichi Sato, Akihisa Osakabe, Hiroaki Tachiwana, Yuko Sato, Yasuha Kinugasa, Tsuyoshi Ikura, Masaaki Sugiyama, Mamoru Sato, Hitoshi Kurumizaka. Structural basis of a nucleosome containing histone H2A.B/H2A.Bbd that transiently associates with reorganized chromatin, Scientific Reports, vol. 3, Dec. 2013.
• Yuko Sato, Masanori Mukai, Jun Ueda, Michiko Muraki, Timothy J. Stasevich, Naoki Horikoshi, Tomoya Kujirai, Hiroaki Kita, Taisuke Kimura, Seiji Hira, Yasushi Okada, Yoko Hayashi-Takanaka, Chikashi Obuse, Hitoshi Kurumizaka, Atsuo Kawahara, Kazuo Yamagata, Naohito Nozaki, Hiroshi Kimura. Genetically encoded system to track histone modification in vivo, Scientific Reports, vol. 3, Aug. 2013.
• Y. Mishima, M. Watanabe, T. Kawakami, C. D. Jayasinghe, J. Otani, Y. Kikugawa, M. Shirakawa, H. Kimura, O. Nishimura, S. Aimoto, S. Tajima, I. Suetake. Hinge and chromoshadow of HP1alpha participate in recognition of K9 methylated histone H3 in nucleosomes, Journal of molecular biology, Vol. 425, No. 1, pp. 54-70, 2013.
• S. Kuroki, M. Akiyoshi, M. Tokura, H. Miyachi, Y. Nakai, H. Kimura, Y. Shinkai, M. Tachibana. JMJD1C, a JmjC domain-containing protein, is required for long-term maintenance of male germ cells in mice, Biology of reproduction, Vol. 89, No. 4, pp. 93, 2013.
• D. Inoue, J. Kitaura, K. Togami, K. Nishimura, Y. Enomoto, T. Uchida, Y. Kagiyama, K. C. Kawabata, F. Nakahara, K. Izawa, T. Oki, A. Maehara, M. Isobe, A. Tsuchiya, Y. Harada, H. Harada, T. Ochiya, H. Aburatani, H. Kimura, F. Thol, M. Heuser, R. L. Levine, O. Abdel-Wahab, T. Kitamura. Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations, The Journal of clinical investigation, Vol. 123, No. 11, pp. 4627-40, 2013.
• H. Ideno, A. Shimada, K. Imaizumi, H. Kimura, M. Abe, K. Nakashima, A. Nifuji. Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development, Gene expression patterns : GEP, Vol. 13, No. 3-4, pp. 84-90, 2013.
• N. Horikoshi, K. Sato, K. Shimada, Y. Arimura, A. Osakabe, H. Tachiwana, Y. Hayashi-Takanaka, W. Iwasaki, W. Kagawa, M. Harata, H. Kimura, H. Kurumizaka. Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2, Acta crystallographica. Section D, Biological crystallography, Vol. 69, No. Pt 12, pp. 2431-9, 2013.
• A. Eberhart, Y. Feodorova, C. Song, G. Wanner, E. Kiseleva, T. Furukawa, H. Kimura, G. Schotta, H. Leonhardt, B. Joffe, I. Solovei. Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina, Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 21, No. 5, pp. 535-54, 2013.
• C. Dinant, G. Ampatziadis-Michailidis, H. Lans, M. Tresini, A. Lagarou, M. Grosbart, A. F. Theil, W. A. van Cappellen, H. Kimura, J. Bartek, M. Fousteri, A. B. Houtsmuller, W. Vermeulen, J. A. Marteijn. Enhanced chromatin dynamics by FACT promotes transcriptional restart after UV-induced DNA damage, Molecular cell, Vol. 51, No. 4, pp. 469-79, 2013.
• K. Deguchi, G. Nagamatsu, H. Miyachi, Y. Kato, S. Morita, H. Kimura, S. Kitano, I. Hatada, Y. Saga, M. Tachibana, Y. Shinkai. Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells, Biology of reproduction, Vol. 88, No. 2, pp. 36, 2013.
• Hiroshi Kimura. Pericentric heterochromatin generated by HP1 interaction-defective histone methyltransferase Suv39h1, J Biol Chem, 2013.
• Y. Arimura, H. Kimura, T. Oda, K. Sato, A. Osakabe, H. Tachiwana, Y. Sato, Y. Kinugasa, T. Ikura, M. Sugiyama, M. Sato, H. Kurumizaka. Structural basis of a nucleosome containing histone H2A.B/H2A.Bbd that transiently associates with reorganized chromatin, Scientific reports, Vol. 3, pp. 3510, 2013.
• L. Abd Al Kader, T. Oka, K. Takata, X. Sun, H. Sato, I. Murakami, T. Toji, A. Manabe, H. Kimura, T. Yoshino. In aggressive variants of non-Hodgkin lymphomas, Ezh2 is strongly expressed and polycomb repressive complex PRC1.4 dominates over PRC1.2, Virchows Archiv : an international journal of pathology, Vol. 463, No. 5, pp. 697-711, 2013.
• Muramatsu, D., Singh, P.B., Kimura, H., Tachibana, M., Shinkai, Y., Hiroshi Kimura. Pericentric heterochromatin generated by HP1 protein interaction-defective histone methyltransferase Suv39h, Journal of Biological Chemistry, Vol. 288, No. 35, pp. 25285-25296, 2013.  公式リンク  
  
• Y. Sato, M. Mukai, J. Ueda, M. Muraki, T. J. Stasevich, N. Horikoshi, T. Kujirai, H. Kita, T. Kimura, S. Hira, Y. Okada, Y. Hayashi-Takanaka, C. Obuse, H. Kurumizaka, A. Kawahara, K. Yamagata, N. Nozaki, H. Kimura. Genetically encoded system to track histone modification in vivo, Scientific reports, Vol. 3, pp. 2436, 2013.
• A. Osakabe, H. Tachiwana, M. Takaku, T. Hori, C. Obuse, H. Kimura, T. Fukagawa, H. Kurumizaka. Vertebrate Spt2 is a novel nucleolar histone chaperone that assists in ribosomal DNA transcription, Journal of cell science, Vol. 126, No. Pt 6, pp. 1323-32, 2013.
• R. S. Nozawa, K. Nagao, K. T. Igami, S. Shibata, N. Shirai, N. Nozaki, T. Sado, H. Kimura, C. Obuse. Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway, Nature structural & molecular biology, Vol. 20, No. 5, pp. 566-73, 2013.
• M. Sadaie, R. Salama, T. Carroll, K. Tomimatsu, T. Chandra, A. R. Young, M. Narita, P. A. Perez-Mancera, D. C. Bennett, H. Chong, H. Kimura. Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence, Genes & development, Vol. 27, No. 16, pp. 1800-8, 2013.
• Hiroshi Kimura. Uneven alterations in the lamin B1 genomic profile regulate heterochromatin formation and gene expression during senescence., Genes Dev, 2013.
• Y. Yokoyama, M. Hieda, Y. Nishioka, A. Matsumoto, S. Higashi, H. Kimura, H. Yamamoto, M. Mori, S. Matsuura, N. Matsuura. Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo, Cancer science, Vol. 104, No. 7, pp. 889-95, 2013.
• H. Tachiwana, Y. Miya, N. Shono, J. Ohzeki, A. Osakabe, K. Otake, V. Larionov, W. C. Earnshaw, H. Kimura, H. Masumoto, H. Kurumizaka. Nap1 regulates proper CENP-B binding to nucleosomes, Nucleic acids research, Vol. 41, No. 5, pp. 2869-80, 2013.
• W. H. Shang, T. Hori, N. M. Martins, A. Toyoda, S. Misu, N. Monma, I. Hiratani, K. Maeshima, K. Ikeo, A. Fujiyama, H. Kimura, W. C. Earnshaw, T. Fukagawa. Chromosome engineering allows the efficient isolation of vertebrate neocentromeres, Developmental cell, Vol. 24, No. 6, pp. 635-48, 2013.
• Asayama K, Ohkubo T, Metoki H, Obara T, Inoue R, Kikuya M, Thijs L, Staessen JA, Imai Y, Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP), Hiroshi Kimura. Cardiovascular outcomes in the first trial of antihypertensive therapy guided by self-measured home blood pressure., Nov. 2012.  公式リンク  
  
• K. Sato, M. Ishiai, K. Toda, S. Furukoshi, A. Osakabe, H. Tachiwana, Y. Takizawa, W. Kagawa, H. Kitao, N. Dohmae, C. Obuse, H. Kimura, M. Takata, H. Kurumizaka. Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair, The EMBO journal, Vol. 31, No. 17, pp. 3524-36, 2012.
• K. Yamagata, D. Iwamoto, Y. Terashita, C. Li, S. Wakayama, Y. Hayashi-Takanaka, H. Kimura, K. Saeki, T. Wakayama. Fluorescence cell imaging and manipulation using conventional halogen lamp microscopy, PloS one, Vol. 7, No. 2, pp. e31638, 2012.
• A. Vielle, J. Lang, Y. Dong, S. Ercan, C. Kotwaliwale, A. Rechtsteiner, A. Appert, Q. B. Chen, A. Dose, T. Egelhofer, H. Kimura, P. Stempor, A. Dernburg, J. D. Lieb, S. Strome, J. Ahringer. H4K20me1 contributes to downregulation of X-linked genes for C. elegans dosage compensation, PLoS genetics, Vol. 8, No. 9, pp. e1002933, 2012.
• Y. Ushijima, Y. H. Inoue, T. Konishi, D. Kitazawa, H. Yoshida, K. Shimaji, H. Kimura, M. Yamaguchi. Roles of histone H3K9 methyltransferases during Drosophila spermatogenesis, Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 20, No. 3, pp. 319-31, 2012.
• J. Ohzeki, J. H. Bergmann, N. Kouprina, V. N. Noskov, M. Nakano, H. Kimura, W. C. Earnshaw, V. Larionov, H. Masumoto. Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly, The EMBO journal, Vol. 31, No. 10, pp. 2391-402, 2012.
• M. Kubiura, M. Okano, H. Kimura, F. Kawamura, M. Tada. Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells, Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 20, No. 7, pp. 837-48, 2012.
• J. M. Kim, T. K. To, J. Ishida, A. Matsui, H. Kimura, M. Seki. Transition of chromatin status during the process of recovery from drought stress in Arabidopsis thaliana, Plant & cell physiology, Vol. 53, No. 5, pp. 847-56, 2012.
• T. Katayama, H. Kobayashi, T. Okamura, Y. Yamasaki-Katayama, T. Kibayashi, H. Kimura, K. Ohsawa, S. Kohsaka, M. Minami. Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase, PloS one, Vol. 7, No. 7, pp. e40813, 2012.
• K. Karmodiya, A. R. Krebs, M. Oulad-Abdelghani, H. Kimura, L. Tora. H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells, BMC genomics, Vol. 13, pp. 424, 2012.
• Y. Hirano, K. Hizume, H. Kimura, K. Takeyasu, T. Haraguchi, Y. Hiraoka. Lamin B receptor recognizes specific modifications of histone H4 in heterochromatin formation, The Journal of biological chemistry, Vol. 287, No. 51, pp. 42654-63, 2012.
• A. Eberhart, H. Kimura, H. Leonhardt, B. Joffe, I. Solovei. Reliable detection of epigenetic histone marks and nuclear proteins in tissue cryosections, Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 20, No. 7, pp. 849-58, 2012.
• T. Chandra, K. Kirschner, J. Y. Thuret, B. D. Pope, T. Ryba, S. Newman, K. Ahmed, S. A. Samarajiwa, R. Salama, T. Carroll, R. Stark, R. Janky, M. Narita, L. Xue, A. Chicas, S. Nunez, R. Janknecht, Y. Hayashi-Takanaka, M. D. Wilson, A. Marshall, D. T. Odom, M. M. Babu, D. P. Bazett-Jones, S. Tavare, P. A. Edwards, S. W. Lowe, H. Kimura, D. M. Gilbert. Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation, Molecular cell, Vol. 47, No. 2, pp. 203-14, 2012.
• E. Brookes, I. de Santiago, D. Hebenstreit, K. J. Morris, T. Carroll, S. Q. Xie, J. K. Stock, M. Heidemann, D. Eick, N. Nozaki, H. Kimura, J. Ragoussis, S. A. Teichmann, A. Pombo. Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs, Cell stem cell, Vol. 10, No. 2, pp. 157-70, 2012.
• J. H. Bergmann, J. N. Jakubsche, N. M. Martins, A. Kagansky, M. Nakano, H. Kimura, D. A. Kelly, B. M. Turner, H. Masumoto, V. Larionov, W. C. Earnshaw. Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function, Journal of cell science, Vol. 125, No. Pt 2, pp. 411-21, 2012.
• J. H. Bergmann, M. G. Rodriguez, N. M. Martins, H. Kimura, D. A. Kelly, H. Masumoto, V. Larionov, L. E. Jansen, W. C. Earnshaw. Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore, The EMBO journal, Vol. 30, No. 2, pp. 328-40, 2011.
• Y. Yamazaki, R. Tokumasu, H. Kimura, S. Tsukita. Role of claudin species-specific dynamics in reconstitution and remodeling of the zonula occludens, Molecular biology of the cell, Vol. 22, No. 9, pp. 1495-504, 2011.
• A. Hagiwara, Y. Tanaka, R. Hikawa, N. Morone, A. Kusumi, H. Kimura, M. Kinoshita. Submembranous septins as relatively stable components of actin-based membrane skeleton, Cytoskeleton (Hoboken, N.J.), Vol. 68, No. 9, pp. 512-25, 2011.
• Y. Hayashi-Takanaka, K. Yamagata, T. Wakayama, T. J. Stasevich, T. Kainuma, T. Tsurimoto, M. Tachibana, Y. Shinkai, H. Kurumizaka, N. Nozaki, H. Kimura. Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling, Nucleic acids research, Vol. 39, No. 15, pp. 6475-88, 2011.
• T. Kondo, K. Hamao, K. Kamijo, H. Kimura, M. Morita, M. Takahashi, H. Hosoya. Enhancement of myosin II/actin turnover at the contractile ring induces slower furrowing in dividing HeLa cells, The Biochemical journal, Vol. 435, No. 3, pp. 569-76, 2011.
• T. Liu, A. Rechtsteiner, T. A. Egelhofer, A. Vielle, I. Latorre, M. S. Cheung, S. Ercan, K. Ikegami, M. Jensen, P. Kolasinska-Zwierz, H. Rosenbaum, H. Shin, S. Taing, T. Takasaki, A. L. Iniguez, A. Desai, A. F. Dernburg, H. Kimura, J. D. Lieb, J. Ahringer, S. Strome, X. S. Liu. Broad chromosomal domains of histone modification patterns in C. elegans, Genome research, Vol. 21, No. 2, pp. 227-36, 2011.
• H. Tachiwana, W. Kagawa, T. Shiga, A. Osakabe, Y. Miya, K. Saito, Y. Hayashi-Takanaka, T. Oda, M. Sato, S. Y. Park, H. Kimura, H. Kurumizaka. Crystal structure of the human centromeric nucleosome containing CENP-A, Nature, Vol. 476, No. 7359, pp. 232-5, 2011.
• H. Tachiwana, A. Osakabe, T. Shiga, Y. Miya, H. Kimura, W. Kagawa, H. Kurumizaka. Structures of human nucleosomes containing major histone H3 variants, Acta crystallographica. Section D, Biological crystallography, Vol. 67, No. Pt 6, pp. 578-83, 2011.
• T. K. To, J. M. Kim, A. Matsui, Y. Kurihara, T. Morosawa, J. Ishida, M. Tanaka, T. Endo, T. Kakutani, T. Toyoda, H. Kimura, S. Yokoyama, K. Shinozaki, M. Seki. Arabidopsis HDA6 regulates locus-directed heterochromatin silencing in cooperation with MET1, PLoS genetics, Vol. 7, No. 4, pp. e1002055, 2011.
• Tachiwana H, Kagawa W, Osakabe A, Kawaguchi K, Shiga T, Hayashi-Takanaka Y, Kimura H, Kurumizaka H. Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T., June 2010.  公式リンク  
  
• H. Numa, J. M. Kim, A. Matsui, Y. Kurihara, T. Morosawa, J. Ishida, Y. Mochizuki, H. Kimura, K. Shinozaki, T. Toyoda, M. Seki, M. Yoshikawa, Y. Habu. Transduction of RNA-directed DNA methylation signals to repressive histone marks in Arabidopsis thaliana, The EMBO journal, Vol. 29, No. 2, pp. 352-62, 2010.
• R. S. Nozawa, K. Nagao, H. T. Masuda, O. Iwasaki, T. Hirota, N. Nozaki, H. Kimura, C. Obuse. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation, Nature cell biology, Vol. 12, No. 7, pp. 719-27, 2010.
• T. Matsui, D. Leung, H. Miyashita, I. A. Maksakova, H. Miyachi, H. Kimura, M. Tachibana, M. C. Lorincz, Y. Shinkai. Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET, Nature, Vol. 464, No. 7290, pp. 927-31, 2010.
• H. Kimura, Y. Hayashi-Takanaka, K. Yamagata. Visualization of DNA methylation and histone modifications in living cells, Current opinion in cell biology, Vol. 22, No. 3, pp. 412-8, 2010.
• A. E. Kelly, C. Ghenoiu, J. Z. Xue, C. Zierhut, H. Kimura, H. Funabiki. Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B, Science (New York, N.Y.), Vol. 330, No. 6001, pp. 235-9, 2010.
• S. Inagaki, A. Miura-Kamio, Y. Nakamura, F. Lu, X. Cui, X. Cao, H. Kimura, H. Saze, T. Kakutani. Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome, The EMBO journal, Vol. 29, No. 20, pp. 3496-506, 2010.
• H. Hashimoto, Y. Takami, E. Sonoda, T. Iwasaki, H. Iwano, M. Tachibana, S. Takeda, T. Nakayama, H. Kimura, Y. Shinkai. Histone H1 null vertebrate cells exhibit altered nucleosome architecture, Nucleic acids research, Vol. 38, No. 11, pp. 3533-45, 2010.
• H. Furuhashi, T. Takasaki, A. Rechtsteiner, T. Li, H. Kimura, P. M. Checchi, S. Strome, W. G. Kelly. Trans-generational epigenetic regulation of C. elegans primordial germ cells, Epigenetics & chromatin, Vol. 3, No. 1, pp. 15, 2010.
• N. Reynoird, B. E. Schwartz, M. Delvecchio, K. Sadoul, D. Meyers, C. Mukherjee, C. Caron, H. Kimura, S. Rousseaux, P. A. Cole, D. Panne, C. A. French, S. Khochbin. Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains, The EMBO journal, Vol. 29, No. 17, pp. 2943-52, 2010.
• A. Rechtsteiner, S. Ercan, T. Takasaki, T. M. Phippen, T. A. Egelhofer, W. Wang, H. Kimura, J. D. Lieb, S. Strome. The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny, PLoS genetics, Vol. 6, No. 9, pp. e1001091, 2010.
• Y. Hayashi-Takanaka, K. Yamagata, N. Nozaki, H. Kimura. Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase, The Journal of cell biology, Vol. 187, No. 6, pp. 781-90, 2009.
• Goto Y, Kimura H. Inactive X chromosome-specific histone H3 modifications and CpG hypomethylation flank a chromatin boundary between an X-inactivated and an escapegene, Nucleic Acids Res, Vol. 37, pp. pp7416, 2009.
• S. Cardinale, J. H. Bergmann, D. Kelly, M. Nakano, M. M. Valdivia, H. Kimura, H. Masumoto, V. Larionov, W. C. Earnshaw. Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier, Molecular biology of the cell, Vol. 20, No. 19, pp. 4194-204, 2009.
• Y. Wada, Y. Ohta, M. Xu, S. Tsutsumi, T. Minami, K. Inoue, D. Komura, J. Kitakami, N. Oshida, A. Papantonis, A. Izumi, M. Kobayashi, H. Meguro, Y. Kanki, I. Mimura, K. Yamamoto, C. Mataki, T. Hamakubo, K. Shirahige, H. Aburatani, H. Kimura, T. Kodama, P. R. Cook, S. Ihara. A wave of nascent transcription on activated human genes, Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 43, pp. 18357-61, 2009.
• A. Ishimura, M. Terashima, H. Kimura, K. Akagi, Y. Suzuki, S. Sugano, T. Suzuki. Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene, Biochemical and biophysical research communications, Vol. 389, No. 2, pp. 366-71, 2009.
• J. Yomoda, M. Muraki, N. Kataoka, T. Hosoya, M. Suzuki, M. Hagiwara, H. Kimura. Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A, Genes to cells : devoted to molecular & cellular mechanisms, Vol. 13, No. 3, pp. 233-44, 2008.
• J. M. Kim, T. K. To, J. Ishida, T. Morosawa, M. Kawashima, A. Matsui, T. Toyoda, H. Kimura, K. Shinozaki, M. Seki. Alterations of lysine modifications on the histone H3 N-tail under drought stress conditions in Arabidopsis thaliana, Plant & cell physiology, Vol. 49, No. 10, pp. 1580-8, 2008.
• S. Hirayama, Y. Yamazaki, A. Kitamura, Y. Oda, D. Morito, K. Okawa, H. Kimura, D. M. Cyr, H. Kubota, K. Nagata. MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination, Molecular biology of the cell, Vol. 19, No. 3, pp. 899-911, 2008.
• H. Tachiwana, A. Osakabe, H. Kimura, H. Kurumizaka. Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro, Nucleic acids research, Vol. 36, No. 7, pp. 2208-18, 2008.
• M. Tachibana, Y. Matsumura, M. Fukuda, H. Kimura, Y. Shinkai. G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription, The EMBO journal, Vol. 27, No. 20, pp. 2681-90, 2008.
• H. Kimura, Y. Hayashi-Takanaka, Y. Goto, N. Takizawa, N. Nozaki. The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies, Cell structure and function, Vol. 33, No. 1, pp. 61-73, 2008.
• Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R, Yoder K, Izumi S, Kuraoka I, Tanaka K, Kimura H. DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics., Mol Cell Biol, Vol. 27, pp. pp7028, 2007.
• Hashimoto H, Sonoda E, Takami Y, Kimura H, Nakayama T, Tachibana M, Takeda S, Shinkai Y. "Histone H1 variant, H1R is involved in DNA damage response.", DNA Repair (Amst), Vol. 6, pp. pp1584, 2007.
• Nojima T, Hirose T, Kimura H, Hagiwara M. The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export., J Biol Chem, Vol. 282, pp. pp15645, 2007.
• Shiomi Y, Masutani C, Hanaoka F, Kimura H, Tsurimoto T. "A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity.", J Biol Chem, Vol. 282, pp. pp20906, 2007.
• Kimura H, Niimi A, Lehmann A, Zhao GY, Hochegger H, Boulton SJ, Takeda S. Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells., Cancer Res, Vol. 67, pp. pp8536, 2007.
• Kimura H, Takizawa N, Allemand E, Hori T, Iborra FJ, Nozaki N, Muraki M, Hagiwara M, Krainer AR, Fukagawa T, Okawa K. "A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B. ", J Cell Biol, Vol. 175, pp. pp389, 2006.
• Kitamura A, Kubota H, Pack CG, Matsumoto G, Takahashi Y, Kimura H, Kinjo M, Morimoto RI, Nagata K. Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state., Nat Cell Biol, Vol. 8, pp. pp1163, 2006.
• Mikami Y, Hori T, Kimura H, Fukagawa T. The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis., Mol Cell Biol, Vol. 25, pp. pp1958, 2005.
• Minoshima Y, Hori T, Okada M, Kimura H, Haraguchi T, Hiraoka Y, Bao YC, Kawashima T, Kitamura T, Fukagawa T. The constitutive centromere component CENP-50 is required for recovery from spindle damage., Mol Cell Biol, Vol. 25, pp. pp10315, 2005.
• Iborra FJ, Kimura H, Cook PR. The functional organization of mitochondrial genomes in human cells., BMC Biol, Vol. 2, pp. 9, 2004.
• Muraki M, Ohkawara B, Hosoya T, Onogi H, Koizumi J, Koizumi T, Sumi K, Yomoda J, Murray MV, Kimura H, Furuichi K, Shibuya H, Krainer AR, Suzuki M, Hagiwara M. Manipulation of alternative splicing by a newly developed inhibitor of Clks., J Biol Chem, Vol. 279, pp. pp24246, 2004.
• Inoue K, Zama T, Kamimoto T, Aoki R, Ikeda Y, Kimura H, Hagiwara M. TNFalpha-induced ATF3 expression is bidirectionally regulated by the JNK and ERK pathways in vascular endothelial cells., Genes Cells, Vol. 9, pp. pp59, 2004.
• Hori T, Haraguchi T, Hiraoka Y, Kimura H, Fukagawa T. Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells, J Cell Sci, Vol. 116, pp. pp3347, 2003.
• D?ringer C, Hamiche A, Gustafsson L, Kimura H, Svanborg C. HAMLET interacts with histones and chromatin in tumor cell nuclei., J Biol Chem, Vol. 278, pp. pp41528, 2003.
• Tatsumi Y, Ohta S, Kimura H, Tsurimoto T, Obuse C. The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1., J Biol Chem, Vol. 278, pp. pp41528, 2003.
• Kudo Y, Boyd CA, Kimura H, Cook PR, Redman CW, Sargent IL. Quantifying the syncytialisation of human placental trophoblast BeWo cells grown in vitro., Biochim Biophys Acta, Vol. 1640, pp. ｐｐ25, 2003.
• Suzuki H, Wu J, Hossain K, Ohhata T, Du J, Akhand AA, Hayakawa A, Kimura H, Hagiwara M, Nakashima I. Involvement of MKK6 in TCRalphabeta(int)CD69lo: a target population for apoptotic cell death in thymocytes., FASEB J, Vol. 17, pp. pp1538, 2003.
• Kwek KY, Murphy S, Furger A, Thomas B, O'Gorman W, Kimura H, Proudfoot NJ, Akoulitchev A. U1 snRNA associates with TFIIH and regulates transcriptional initiation., Nat Struct Biol, Vol. 9, pp. ｐｐ800, 2002.
• Ishimi Y, Okayasu I, Kato C, Kwon HJ, Kimura H, Yamada K, Song SY. Enhanced expression of Mcm proteins in cancer cells derived from uterine cervix, Eur J Biochem, Vol. 270, pp. ｐｐ1089, 2002.
• Kimura H, Sugaya K, Cook PR. The transcription cycle of RNA polymerase II in living cells., J Cell Biol, Vol. 159, pp. ｐｐ777, 2002.
• Kimura H, Cook PR. Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B, J Cell Biol, Vol. 153, pp. pp1341, 2001.
• Takebayashi SI, Manders EM, Kimura H, Taguchi H, Okumura K. Mapping sites where replication initiates in mammalian cells using DNA fibers, Exp Cell Res, Vol. 271, pp. ｐｐ263, 2001.
• Jones E, Kimura H, Vigneron M, Wang Z, Roeder RG, Cook PR. "Isolation and characterization of monoclonal antibodies directed against subunits of human RNA polymerases I, II, and III.", Exp Cell Res, Vol. 254, pp. pp163, 2000.
• Kuwahara K, Yoshida M, Kondo E, Sakata A, Watanabe Y, Abe E, Kouno Y, Tomiyasu S, Fujimura S, Tokuhisa T, Kimura H, Ezaki T, Sakaguchi N. "A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication", Blood, Vol. 95, pp. pp2321, 2000.
• Wade-Martins R, White RE, Kimura H, Cook PR, James MR. Stable correction of a genetic deficiency in human cells by an episome carrying a 115 kb genomic transgene., Nature Biotechnol, Vol. 18, pp. pp1311, 2000.
• Kimura H, Tao Y, Roeder RG, Cook PR. Direct imaging of DNA in living cells reveals the dynamics of chromosome formation., Mol Cell Biol, Vol. 19, pp. pp5385, 1999.
• Manders EM, Kimura H, Cook PR. Direct imaging of DNA in living cells reveals the dynamics of chromosome formation., J Cell Biol, Vol. 144, pp. pp813, 1999.
• Ishimi Y, Komamura Y, You Z, Kimura H. Biochemical function of mouse minichromosome maintenance 2 protein, J Biol Chem, Vol. 273, pp. pp8369, 1998.
• Ishimi Y, Ichinose S, Omori A, Kimura H. Binding of human minichromosome maintenance proteins with histone H3, J Biol Chem, Vol. 271, pp. pp24115, 1996.
• Yoshida I, Kimura H, Takagi N. The mouse Mcmd gene for DNA replication protein P1MCM3 maps to bands A3-A5 on chromosome 1 by fluorescence in situ hybridization., Genomics, Vol. 32, pp. pp483, 1996.
• Kimura H, Ohtomo T, Yamaguchi M, Ishii A, Sugimoto K. Mouse MCM proteins: complex formation and transportation to the nucleus., Genes Cells, Vol. 1, pp. pp977, 1996.
• Takizawa N, Kimura H, Sugimoto K. "Sequence of mouse CDC47, a member of the minichromosome maintenance (Mcm) family involved in the DNA replication licensing system.", Gene, Vol. 167, pp. pp343, 1995.
• Kimura H, Takizawa N, Nozaki N, Sugimoto K. Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins., Nucleic Acids Res, Vol. 23, pp. pp2097, 1995.
• Kimura H, Nozaki N, Sugimoto K. "DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. ", EMBO J, Vol. 13, pp. pp4311, 1994.

著書

• 木村宏. エピゲノム解析手法の標準化；ヒストン修飾解析, 実験医学増刊：『エピゲノム研究：修飾の全体像の理解から先制・個別化医療へ』, 羊土社, p. 32－37, 2017.
• 田代聡, 木村宏. Nucleome研究の世界動向, 実験医学, 羊土社, Vol. 35, p. 78－82, 2017.
• 木村宏, 田代聡. ヌクレオソーム解析時代の幕開け, 細胞工学, 学研メディカル秀潤社, Vol. 35, No. 2, p. 66－69, 2016.
• 木村宏. 遺伝子活性化のしくみの生きた細胞内での観察, パリティ, 丸善出版株式会社, Vol. 31, No. 1, p. 70－72, 2016.
• Hiroshi Kimura, Yuko Sato. DNA replication and histone modification, DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology, pp. 469-488, 2016.
• 原口徳子, 木村宏, 平岡泰. 新・生細胞 蛍光イメージング, 新・生細胞 蛍光イメージング, 共立出版, Nov. 2015.
• 木村宏. 転写, 生体の科学, 医学書院, Vol. 6, No. 5, p. 468-469, Oct. 2015.
• 木村宏. 単一細胞解析から明らかになった転写を制御するヒストン修飾の役割, 細胞工学, 学研メディカル秀潤社, Vol. 34, No. 3, pp. 271－272, Feb. 2015.
• 木村宏. 生細胞イメージングで解き明かすエピジェネティクな遺伝子発現の制御, 科研費ＮＥＷＳ, 日本学術振興会研究事業部企画調査室, Vol. 2, p. 12, 2015.

国際会議発表 (査読有り)

• Junya Adachi, Toshiaki Fukushima, Haruka Oda, Hiroka Sugai, Kohei Sato, Hiroshi Kimura, Kazushi Kinbara. Development of Anthracene-Based Fluorescent Probes for Application in Cellular Systems, The 19th International Symposium on Novel Aromatic Compounds, July 2022.
• Satoshi Uchino, Yuma Ito, Jessica Dai, Yuko Sato, Tetsuya Handa, Yasuyuki Ohkawa, Makio Tokunaga, Hiroshi Kimura. Live imaging of the initiation and elongation forms of RNA polymerase II using phosphorylation-specific probes., The 30th Hot Spring Harbor International Symposium(Online), Jan. 2022.
• Yuko Sato, Lennart Hilbert, Vasily Zaburdaev, Nadine Vastenhouw, Hiroshi Kimura. Histone modification dynamics during zygotic genome activation, International Symposium for Female Researchers in Chromatin Biology 2019, June 2019.
• Ideno, Hisashi, Kamiunten, Taichi, Shimada, Akemi, Terashima, Tatsuo, Nakashima, Kazuhisa, Tomooka, Yasuhiro, Nakamura, Yoshiki, Hiroshi Kimura, Tachibana, Makoto, Nifuji, Akira. H3K9MTase G9a regulates tooth development in mice., Annual Meeting of the American-Society-for-Bone-and-Mineral-Research (ASBMR), JOURNAL OF BONE AND MINERAL RESEARCH, WILEY, Vol. 32, pp. S334-S334, Dec. 2017.
• Nanasi, P., Imre, L., Horvath, A., Halasz, L., Szanto, A., Hiroshi Kimura, Szekvolgyi, L., Nagy, L., Szabo, G.. Breaking good:+1 nucleosome destabilization by nicking, 42nd Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back, FEBS JOURNAL, WILEY, Vol. 284, pp. 221-221, Sept. 2017.
• Ideno, H., Komatsu, K., Shimada, A., Arai, Y., Nakashima, K., Tachibana, M., Hiroshi Kimura, Nifuji, A.. Histone methyltransferase G9a is essential for osteoblastic differentiation and skull bone formation during development., ASCB/EMBO Meeting, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 28, 2017.
• Hilbert, L., Sato, Y., Hiroshi Kimura, Julicher, F., Honigmann, A., Zaburdaev, V., Vastenhouw, N.. Interphase chromatin is adaptively folded by ongoing transcription and RNA accumulation., ASCB/EMBO Meeting, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 28, 2017.
• Handoko, L., Chang, J., Kaczkowski, B., Fujita, K., Lizio, M., Sato, Y., Wakamori, M., Hiroshi Kimura, Taniguchi, Y., Yanagida, T., Umehara, T., Minoda, A.. Studying combinatorial histone modifications, Annual Meeting of the American-Society-for-Cell-Biology (ASCB), MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 27, 2016.
• Koide, Shuhei, Takubo, Keiyo, Oshima, Motohiko, Miyagi, Satoru, Saraya, Atsunori, Wang, Changshan, Matsui, Hirotaka, Hiroshi Kimura, Shinkai, Yoichi, Suda, Toshio, Iwama, Atsushi. HISTONE METHYLTRANSFERASE SETDB1 REGULATES ENERGY METABOLISM IN HEMATOPOIETIC STEM AND PROGENITOR CELLS, 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), EXPERIMENTAL HEMATOLOGY, ELSEVIER SCIENCE INC, Vol. 43, No. 9, pp. S73-S73, Sept. 2015.
• Ito Y, Harata M, Kimura K, Sakata-Sogawa K, Tokunaga M. Dynamics of INO80 Chromatin Remodeling Complex by Live-cell Molecular Imaging., International Symposium on Chromatin Structure, Dynamics, and Function, Aug. 2015.
• Hiroshi Kimura. Kinetics of Histone and RNA Polymerase Ⅱ Modifications during Transcriptional Activation, 2015.
• Hiroshi Kimura. Histone modifications associated with transcriptional activation of coding and non-coding DNA in living cells, 2015.
• Hiroshi Kimura. Chromatin modification dynamics in transcriptional activation, 2015.
• Hiroshi Kimura. Detecting protein function in living cells:From mobility analysis to posttranslational modification tracking, 2015.
• Yuma Ito, Hiroshi Kimura, Hitoshi Kurumizaka, Masahiko Harada, Kumiko Sakata-Sogawa, Makio Tokunaga. Integrated Imaging Approach to the Study of Chromatin Dynamics, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Kazumitsu Maehara, Akihito Hrada, Yuko Sato, Masaki Matsumoto, Keiichi I.Nakayama, Hiroshi Kimura, Yasuyuki Ohkawa. The Diversity of mouse histone H3 variants, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Brian P.English, Tatsuya Morisaki, Kumiko Sakata-Sogawa, Makio Tokunaga, Naohito Nozaki, Hiroshi Kimura, Timothee Lionnet Timothy J.Stasevich. Towards Single-Gene Imaging of Endogenous Histone and RNA Polumerase ⅡModifications in Living Cells, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Noriko Yasuhara, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Noriko Saitoh, Hiroshi Kimura, Yoshihiro Yoneda. The role of nuclear transport in Chromatin Dynamics, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Masahiro Oka, Sonoko Mura, Kohji Yamada, Percival Sangel, Yasuyuki Ohkawa, Hiroshi Kimura, Yoshihiro Yoneda. Functional analysis of leukemogenic Nup98-Hox fusion protein, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Sin-Ya Isobe, Yoshi-Nobu Ohkubo, Koji Nagao, Naohito Nozaki, Hiroshi Kimura, Chikashi Obuse. DNA Double Strand Breaks Repair Pathwey is Controlled by Differential Phosphorylation of 53BP1, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Jun Ueda, Takashi Urahama, Akihito Harada, Shinichi Machida, Kazumitsu Maehara Naoki Horikoshi, Akihisa Osakabe, Hiroaki Tachiwana, Tatsuma Yao, Minami Yamada, Takashi Iwamoto, Masahito Ikawa, Taro Tachibana, Hiroshi Kimura, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Kazuo Yamagata. Mouse Testis Specific Histone H3 Variant, H3mmT is Essential for Spermatogenesis and Ensures the Entry into Meiosis, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Paulina Rybak, Agnieszka Waligorska, Agnieszka M.Hoang, Lukasz Bujnowicz, Hiroshi Kimura, Jurek Dobrucki. Global Nuclear Changes Induced By Replication Stress, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Takashi Urahama, Akihito Harada, Kazumitsu Maehara, Naoki Horikoshi, Koichi Sato, Yuko Sato, Koji Shiraishi, Norihiro Sugino, Akihisa Osakabe, Hiroaki Tachiwana, Wataru Kagawa, Hiroshi Kimura, Yasuyuki Ohkawa, Hitoshi Kurumizawa. Structural, Biochemical, and Genome-Wide Analyses of Human Histone Variant H3.5, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Hiroyuki Taguchi, Naoki Horikoshi, Koichi Sato, Yasuhiro Arimura, Akihisa Osakabe, Kazumitsu Maehara, Hiroshi Kimura, Yasuyuki Ohkawa, Hitoshi Kurumizaka. Structural and biochemical analyses of the nucleosome containing a novel human H3 variant, H3F3AP6, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Naoki Horikoshi, Koichi Sato, Yasuhiro Arimura, Hiroyuki Oku, Masayuki Kusakabe, Masahiko Harata, Hiroshi Kimura, Hitoshi Kurumizaka. Reconstitution and structural analyses of the heterotypic nucleosome containing H2A.Z and H2A, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Tetsuya Handa, Hiroshi Kimura. Dynamics of Histone Modifications and RNA Polmerase Ⅱin Heat Shock Response, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Yuko Sato, Hiroshi Kimura. Visualizing The Inactive X Chromosome in Living Cells by Using H4K20mel-mintbody, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Tomoya Kujirai, Naoki Horikoshi, Koichi Sato, Kazumitsu Maehara, Akihisa Osakabe, Shinichi Machida, Yasuyuki Ohkawa, Hiroshi Kimura, Hitoshi Kurumizaka. The distinct characters of histone H3.Y nucleosome, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Ito Y, Inaba N, Harata M, Kimura H, Tokunaga M, Sakata-Sogawa K.. Quantitative imaging analysis of molecular dynamics of actin- related protein in the nucleus., 58th Annual Meeting of Biophysical Society, Feb. 2014.

国内会議発表 (査読有り)

• Shuntaro Sato, Yuma Ito, Yuko Sato, Hiroshi Kimura, Makio Tokunaga. Single-molecule imaging of post-translational modification using genetically encoded antibody probe., The 56th Annual Meeting of the Biophysical Society of Japan, Sept. 2018.
• Nagao, Koji, Isobe, Shin-Ya, Ohkubo, Yoshi-Nobu, Hayashi-Takanaka, Yoko, Hiroshi Kimura, Sado, Takashi, Obuse, Chikashi. Constitution of Higher Order Heterochromatin Structure Based on Epigenetic Code, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 91, No. 6, pp. 318-318, Dec. 2016.
• Kajitani, Takuya, Kato, Hiroaki, Chikashige, Yuji, Hiroshi Kimura, Ohkawa, Yasuyuki, Herand, Damien, Murakami, Yota. Phosphorylation at Ser7 of RNA polymerase II CTD limits transcription speed and transcription elongation, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 91, No. 6, pp. 348-348, Dec. 2016.
• 伊藤由馬, 原田昌彦, 木村宏, 十川久美子, 徳永万喜洋. １分子イメージングとFRAPによるINO80クロマチン再構成複合体の核内動態解析, 第8回「光塾」, Dec. 2016.
• Tsubasa Isogaki, Yuma Ito, Shota Ichikawa, Hiroshi Kimura, Masahiko Harata, Kumiko Sakata-Sogawa, Makio Tokunaga. Fluorescence recovery after photobleaching(FRAP) analysis of INO80 chromatin remodeling complex, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• 縣 保年, 我妻 慶祐, 寺田 晃士, 田中 裕之, 伊川 友活, 増田 喬子, 河本 宏, 木村 宏. E2A転写因子 foci を足場としたT細胞受容体遺伝子座の染色体ダイナミクス, 第10回エピジェネティクス研究会年会, 2016.
• 白井 温子, 川口 隆之, 村松 大輔, 石田 真由美, 木村 宏, 中山 潤一, 眞貝 洋一. ヒストンメチル化酵素Suv39h1を介したヘテロクロマチン形成機構の解明, 第10回日本エピジェネティクス研究会年会, 2016.
• 桝本 寛, 庄野 暢晃, 大関 潤一郎, 大竹 興一郎, 長瀬 隆弘, 木村 宏, Larionov Vladimir, Earnshaw William C. 合成セントロメアDNAとtetO/tetRデザリングシステムを用いたセントロメアクロマチン集合機構の解明・キネトコア機能とセントロメアエピヘネティクスの繋がり, 第10回日本エピジェネティクス研究会年会, 2016.
• 大関 淳一郎, 庄野 暢晃, 大竹 興一郎, 久郷 和人, 木村 宏, 長瀬 隆弘, LarionovVladimir, William Earnshaw, 桝本 寛. アセチル化酵素KAT７によるヒストン交換反応はヘテロクロマチン化に拮抗してCENP-A集合を促進する, 2016.
• 梶谷 卓也, 加藤 太陽, 近重 裕次, 平岡 泰, 鈴木 穣, 木村 宏, 大川 恭行, 小布施 力史, Hermand damien, 村上 洋太. RNAPⅡ-CTD Ser7のﾘﾝ酸化は転写を減速させることでncRNAのクロマチン結合を促進しヘテロクロマチン形成を行う, 第10回日本エピジェネティクス研究会年会, 2016.
• 木村 宏, 林 陽子, 大川 恭行, 野崎 直仁. 特異的モノクロナール抗体を用いた被修飾型ヒストンH3の局在と動態の解析, 第10回日本エピジェネティクス研究会年会, 2016.
• 佐藤 優子, 鯨井 智也, 堀越 直樹, 胡桃坂 仁志, 木村 宏. ヒストンH4K20モノメチル化修飾特異的mintbodyを用いた生細胞イメージング, 第10回日本エピジェネティクス研究会年会, 2016.
• 林 陽子, 木村 宏. 単一細胞解析によるヒストン修飾の細胞周期における変動と酵素郡の働き, 第10回日本エピジェネティクス研究会年会, 2016.
• 半田 哲也, 木村 宏. 修飾特異的モノクローナル抗体を用いたヒストン修飾とRNAポリメラーゼⅡの動態解析, 第10回日本エピジェネティクス研究会年会, 2016.
• Kajitani, Takuya, Kato, Hiroaki, Chikashige, Yuji, Hiraoka, Yasushi, Hiroshi Kimura, Ohkawa, Yasuyuki, Nagao, Koji, Obuse, Chikashis, Hermand, Damien, Murakavii, Yota. Ser7 phosphorylation of RNAPII-CTD ensures on-chromatin retention of nascent ncRNAs, facilitating establishment and epigenetic inheritance of RNAi-depnendent heterochromatin formation, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 90, No. 6, pp. 360-360, Dec. 2015.
• Yuma Ito, Hiroshi Kimura, Masahiko Harada, Kumiko Sakata-Sogawa, Makio Tokunaga. Dynamics of actin-related protein 4 in living cell nucleus for dynamic chromatin regulation, 第53回日本生物物理学会年会, Sept. 2015.
• Hiroshi Kimura. Dynamics of actin-related protein 4 in living cell nucleus for dynamic chromatin regulation, Sept. 2015.
• Yuma Ito, Tsubasa Isogaki, Hiroshi Kimura, Masahiko Harada, Kumiko Sakata-Sogawa, Makio Tokunaga. Intranuclear dynamics of INO80 chromatin remodeling complex by fluorescent recovery after photobleaching, 第53回日本生物物理学会年会, Sept. 2015.
• 木村宏. ストレス対応のクロマチンダイナミクス, 2015.
• 木村宏. 細胞周期・メタボリズムとヒストン修飾動態, 2015.
• Hiroshi Kimura. Chromatin modification and transcription activation in vivo, 2015.
• 木村宏. ヒストン修飾と転写制御, 2015.
• 長尾 恒治, 榊原 祐樹, 柴田 幸子, 野澤 竜介, 坂口 武久, 木村 宏, 佐渡 敬, 小布施 力史. アリル特異的ChlP-seq法によるマウス不活性化X染色体のクロマチン動態の解析, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 和田 悟史, 出野 尚, 島田 明美, 上運天 太一, 中村 芳樹, 中島 和久, 木村 宏, 眞貝 洋一, 立花 誠, 二藤 彰. ヒストンメチル化酵素G9a遺伝子欠損による腱の形成阻害, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 原田 哲仁, 佐藤 優子, 木村 宏, 大川 恭行. 多様化した新規マウスヒストンH3バリアントの組織特異的発現の同定と機能解析, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 田中 万結, 新井 大祐, 木村 宏, 中尾 洋一. 味噌に含まれるヒストン修飾制御活性を有する化合物の探索, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 相馬 里奈, 坂本 匠, 田中 万結, 石橋 信宏, 新井 大祐, 木村 宏, 中尾 洋一. LC-MS/MSを用いた味噌中のヒストン修飾活性化合物の探索, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 石橋 信宏, 新井 大祐, 木村 宏, 中尾 洋一. 日本食食材に含まれるヒストン修飾制御成分の探索, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 林 礼佳, 首浦 武作志, 石下 聡, 堀 哲也, 木村 宏, 松田 洋一, 深川 竜郎, 多田 政子. ニワトリにおけるゲノムワイドなエピジェネティクスリプログラミング, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 森田 鋭, 佐藤 優子, 沖山 佳生, 渡邊 千鶴, 梅原 崇史, 本間 光貴, 横山 茂之, 木村 宏. アセチル化ヒストンH4K16を特異的に認識する抗体の結晶構造解析, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• Toru Sengoku, Satoshi Morita, Yuko Sato, Yoshio Okiyama, Chiduru Watanabe, Teruki Honma, Takashi Umehara, Shgeyuki Yokoyama, Hiroshi Kimura. Structural and functional analysis of modified histone peptide interactions with specific antibody recognition, BMB2015, 2015.
• 林（高中）陽子, 野崎 直仁, 木村 宏. 特異的抗体によるヒストンH4修飾動態の単一細胞解析, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 大関 淳一郎, 庄野 暢晃, 大竹 興一郎, 久郷 和人, 木村 宏, 長瀬 隆弘, Vladimir Larionov, William C.Earnshaw, 桝本 寛. M18BP1結合蛋白質であるHDP1(HAT Domain Protein１）は、セントロメアへのCENP-A蛋白質の集合を正に制御し、Suv39h1によるセントロメアの不活性化を防ぐ, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 後藤 萌, 戸田 成美, 吉田 英樹, 井上 喜博, 木村 宏, 山口 政光. ショウジョウバエエピジェネティック制御因子jumonji(djmj)/Jarid2の精子形成過程における核小体局在を制御する仕組み, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• Kohei Shimaji, Takahiro Konishi, Shintaro Tanaka, Hideki Yoshida, Yasuko Kato, Yasuyuki Okawa, Tetsuya Sato, Mikita Suyama, Hiroshi Kimura, Masamitsu Yamaguchi. Functional analyses of Drosophila histone methyltransferase G9a, BMB2015, 2015.
• 向 正則, 平 誠司, 藤原 真人, 中村 翔一, 辻 拓真, 宮形 奈紗, 木村 宏, 小林 悟. 生殖細胞関連遺伝子の発現活性化に関わるエピジェネティックな制御機構, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 磯部 真也, 大久保 義真, 石本 祥平, 長尾 恒治, 野崎 直仁, 木村 宏, 小布施 力史. 新規53BP1結合タンパク質SCAIは、Rif1に阻害的に働くことで相同組換え修復を促進する, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 小出 周平, 田久保 圭誉, 大島 基彦, 宮城 聡, 更屋 敦則, 青山 和正, 王 長山, 松井 啓隆, 木村 宏, 眞貝 洋一, 須田 年生, 岩間 厚志. ヒストンメチル化酵素Stebd1は造血幹前駆細胞のエネルギー代謝に必須である, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 原田 哲仁, 前原 一満, 田口 裕之, 佐藤 優子, 謝 炎, 立花 太郎, 木村 宏, 胡桃坂 仁, 大川 恭行. 新規ヒストンH3バリアントH3mm7は骨格筋分化能を制御する, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 岡 正啓, 村 苑子, 山田 幸司, Percival Sangel, 大川 恭行, 木村 宏, 米田 悦啓. 白血病病因因子Nup98-HoxA9の機能解析, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 上田 潤, 浦浜 崇, 原田 哲仁, 町田 晋一, 前原 一満, 堀越 直樹, 越坂部 晃永, 八尾 竜馬, 山田 みなみ, 岩本 隆司, 磯谷 綾子, 伊川 正人, 立花 太郎, 木村 宏, 大川 恭行, 胡桃坂 仁, 山縣 一夫. マウス精巣特異的ヒストンH3バリアントであるH3tは精子形成過程に必須である, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• 木村 宏, 半田 哲也, 佐藤 優子. 転写誘導におけるヒストンアセチル化の役割, 第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会, 2015.
• Takuya Kajitani, Hiroaki Kato, Yutaka Suzuki, Yuji Chikashige, Hiroshi Kimura, Yasuyuki Ohkawa, Chikashi Obuse, Koji Nagao, Damien Hermand, Yota Murakami. CTD-code of RNA polymerase Ⅱ regulates dynamics of IncRNA for RNAi-dependent heterochromatin, BMB2015, 2015.
• Naomichi Inaba, Yuma Ito, Harata Masahiko, Hiroshi Kimura, Makio Tokunaga, Kumiko Sakata-Sogawa. Quantitative analysis of molecular dynamics of Arp4beta upon transcriptional activation by single-molecule fluorescence imaging and FRAP, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• 新倉和美, 十川久美子, 木村宏, 徳永万喜洋. 転写因子の免疫刺激による共局在の変化：マルチカラー分子イメージング, 第45回日本生物物理学会年会, Dec. 2007.

国際会議発表 (査読なし・不明)

• Yuko Sato, Satoshi Uchino, Hiroshi Kimura. Chromatin mobility of X-linked loci and its transcription regulation, The 30th Hot Spring Harbor International Symposium, Jan. 2022.
• Hiroshi Kimura. Tracking histone and RNA polymerase II modifications in living cells using genetically encoded probes, RIKEN BDR Symposium, Mar. 2021.
• Hiroshi Kimura. Roles of histone acetylation and nuclear F-actin in zebrafish embryo development, Chromosome Dynamics - An international symposium on chromatin and chromosome stability., Dec. 2019.
• Hiroshi Kimura. Single-cell histone modification analysis: from live-cell imaging to epigenome profiling., Single Cell Omics Germany Workshop "Advances in single cell epigenomics 2019", Nov. 2019.
• Hiroshi Kimura. Modification-specific intracellular antibodies for monitoring histone modification in vivo, 3rd Epigenetics and Bioengineering Conference (EpiBio 2019), Sept. 2019.
• Hiroshi Kimura. Chromatin modification dynamics during the activation and inactivation of transcription, Gordon Research Conference "Genome Architecture in Cell Fate and Disease", Aug. 2019.
• Yuko Sato, Hiroshi Kimura. Zygotic genome activation is dynamically mediated by histone acetylation in zebrafish, Cold Spring Harbor Laboratory Meeting “Nuclear Organization & Function”, May 2018.
• Chan-I Chung, Yuki Ohmuro-Matsuyama, Yuko Sato, Hiroshi Kimura, Hiroshi Ueda. Development of intrabody-based FRET probe for monitoring histone H3 acetylation in living cells, Pacifichem 2015, Nov. 2015.

国内会議発表 (査読なし・不明)

• 足立 惇弥, 福嶋 俊明, 小田 春佳, 菅井 祥加, 佐藤 浩平, 木村 宏, 金原 数. 粘度応答性蛍光プローブの開発と生細胞内における応答性, 第17回バイオ関連化学シンポジウム, Sept. 2023.
• 大室有紀, 北口哲也, 上田宏, 木村宏. YFP断片とintrabodyを利用した生細胞内におけるエピジェネティクス変化の観察法構築, 第45回日本分子生物学会年会, 第16回日本エピジェネティクス研究会年会 要旨集, June 2023.
• 足立 惇弥, 小田 春佳, 福嶋 俊明, 菅井 祥加, 佐藤 浩平, 木村 宏, 金原 数. 水溶性蛍光プローブの生細胞内における粘度応答性とメラノソームの可視化, 日本化学会第103春季年会, Mar. 2023.
• Yuko Sato, Hiroshi Kimura. Transcriptional regulation and chromatin modifications during zebrafish zygotic genome activation., 第45回日本分子生物学会年会, Dec. 2022.
• 伊藤 由馬, 木村 宏. 先端技術と理論で迫るクロマチン機能の理解, 第60回日本生物物理学会年会, Sept. 2022.
• 上田 宏, DAI YANCEN, 佐藤 優子, 朱 博, 北口 哲也, 木村 宏, Farid J. Ghadessy. 生細胞内タンパク質の動態観察とそれによる細胞分別が可能な蛍光抗体プローブIntra Q-bodyの構築, 第16回バイオ関連化学シンポジウム 要旨集, Sept. 2022.
• Yuko Sato, Yuma Ito, Satoshi Uchino, Makio Tokunaga, Hiroshi Kimura. Chromatin mobility of X-linked loci and its epigenetic regulation, 第60回日本生物物理学会年会, Sept. 2022.
• 足立惇弥, 福嶋 俊明, 小田 春佳, 菅井 祥加, 佐藤 浩平, 木村 宏, 金原 数. 非TICT型粘度応答性蛍光プローブの開発と生細胞イメージングへの適用, 2022年光化学討論会, Sept. 2022.
• 佐藤優子, 内野哲志, 岡翔平, 木村宏. 小分子抗体プローブを用いたエピジェネティクス修飾動態の生細胞イメージング, 第78回 日本顕微鏡学会学術講演会, May 2022.
• Yancen Dai, Bo Zhu, Yuko Sato, Hiroshi Kimura, Farid J. Ghadessy, Tetsuya Kitaguchi, Hiroshi Ueda.. Development of an immunofluorescence probe Q-body for the direct visualization of tumor marker p53 in fixed and living cells., 化学工学会第87年会, 化学工学会第87年会要旨集, Mar. 2022.
• 小澤弘樹, 神戸梓沙, 日比滉大, 木村宏, 白木伸明, 粂 昭苑. メチオニン除去培養によるエピジェネティック変化を伴うヒトiPS細胞分化促進, 第44回日本分子生物学会, Dec. 2021.
• 内野 哲志, 伊藤 由馬, Jessica Dai, 佐藤 優子, 半田 哲也, 大川 恭行, 徳永 万喜洋, 木村 宏. 転写伸長型RNAポリメラーゼII可視化プローブによる生細胞内における 転写伸長部位の観察, 第44回日本分子生物学会年会, Dec. 2021.
• 内野 哲志, 伊藤 由馬, 佐藤 優子, 半田 哲也, 大川 恭行, 徳永 万喜洋, 木村 宏. リン酸化型RNAポリメラーゼII可視化プローブによる転写部位の生細胞観察, 第39回染色体ワークショップ・第20回核ダイナミクス研究会, オンライン, Dec. 2021.
• 佐藤優子, 内野哲志, 伊藤由馬, 前原一満, 大川恭行, 徳永万喜洋, 木村宏. 生細胞プローブを用いた不活性化X染色体動態と転写制御の解析, 第94回 日本生化学会大会, Nov. 2021.
• Hiroshi Kimura. Gene regulation and chromatin dynamics in living cells, The 79th of Annual Meeting of the Japanese Cancer Association, Oct. 2021.
• 木村 宏. 転写活性化に伴うヒストンアセチル化とクロマチンのダイナミクス, 第93回 日本生化学会大会, Sept. 2021.
• Yuko Sato, Nguyen Thi Bich Ngoc, Haruka Oda, Tetsuya Handa, Hidenori Nishihara, Akihito Harada, Yasuyuki Ohkawa, Hiroshi Kimura. Spatiotemporal dynamics of histone modifications during zebrafish zygotic genome activation, 第43回日本分子生物学会年会, Dec. 2020.
• 佐藤優子, 木村宏. Xist RNAの生細胞動態解析, 第93回日本生化学会大会, Sept. 2020.
• 木村 宏. ゼブラフィッシュ胚性ゲノム活性化におけるヒストンアセチル化の役割と核内環境変化, 第42回日本分子生物学会年会, Dec. 2019.
• Hiroshi Kimura. Tracking RNA polymerase II and histone modification dynamics during the zygotic genome activation, 第92回日本生化学会大会, Oct. 2019.
• 木村宏. ヘテロクロマチンのダイナミクス, 平成31年度遺伝研研究会「クロマチン・細胞核の形成とダイナミクスによるゲノム制御」, Oct. 2019.
• 大室有紀, 北口哲也, 木村宏, 上田宏. YFP断片融合抗体プローブを用いたヒストン翻訳後修飾検出系の構築, 第 71回日本生物工学会大会, 第 71回日本生物工学会大会要旨集, Sept. 2019.
• 大室有紀, 北口哲也, 木村宏, 上田宏. 分割YFP融合Intrabodyを用いた生細胞内ヒストンアセチル化検出プローブの構築, 第19回日本蛋白質科学会年会, 第19回日本蛋白質科学会年会要旨集, June 2019.
• 佐藤優子, 木村宏. 細胞内抗体Mintbodyを用いた生細胞エピジェネティクス解析, 日本エピジェネティクス研究会年会, May 2018.
• Hilbert, Lennart, Yuko Sato, Hiroshi Kimura, Honigmann, Alf, Zaburdaev, Vasily, Vastenhouw, Nadine. Transcription Locally Disperses Chromatin and Thereby Organizes the Global Architecture of Interphase Nuclei, 58th Annual Meeting of the Biophysical-Society, BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 112, No. 3, pp. 211A-211A, Feb. 2017.
• 神戸梓沙, 白木伸明, 木村宏, 粂昭苑. ヒトiPS細胞におけるメチオニン代謝とヒストン修飾の役割, 第39回日本分子生物学会年会, Dec. 2016.
• Ichinomiya Katsuo, Timothy J Stasevich, Hiroshi Kimura, Kumiko Sakata-Sogawa, Makio Tokunaga. Spatio-temporal quantitative analysis of molecular dynamics and interactions in cells using multicolor single-molecules imaging, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• 中村和樹, 児玉信介, 竹山優子, 松岡昌志, 大内和夫, 木村宏, 森山敏文, 若林裕之. 初期校正後のALOS PALSARの校正観測, 日本リモートセンシング学会第45回学術講演会論文集, pp. 209-210, Dec. 2008.

その他の論文・著書など

• Yohei Kono, Stephen A. Adam, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture with BAF and cGAS, Jan. 2022.  公式リンク  
  
• 佐藤優子, 木村宏. 生きた細胞でクロマチン修飾変化を見る Mintbody, 実験医学別冊「クロマチン解析実践プロトコール」, pp. 233-240, Dec. 2020.
• 趙 寧, 森崎達也, 小田春佳, 佐藤優子, 木村 宏, Stasevich Timothy J. タンパク質1分子を翻訳過程からイメージング可能なプローブ「HA Frankenbody」, 実験医学, No. 38, pp. 613－617, Feb. 2020.
• 木村宏, 半田哲也. ヒストン修飾解析の最前線, 遺伝子医学, No. 10, pp. 124－129, Jan. 2020.
• 木村宏. FRAP/FLIP―フォトブリーチによる生細胞内分子動態計測, 実験医学, Vol. 36, no. 20, pp. 3398－3399, Dec. 2018.
• 木村宏. ヒストン修飾と特異的モノクローナル抗体, Dojin News, No. 166, pp. 1－5, Dec. 2018.
• 木村宏. ヒストンの細胞内ダイナミクス, 実験医学, Vol. 36, no. 17, pp. 2890－2896, Nov. 2018.
• 佐藤優子, 木村宏. 遺伝子不活性化マークを生細胞で観察できる蛍光プローブ, 化學工業, Vol. 69, No. 8, pp. 589－594, Aug. 2018.
• 木村宏. ヌクレオームコンソーシアム, 生物物理, Vol. 58, No. 4, pp. 221－222, Apr. 2018.
• 木村宏. 生細胞イメージングによりとらえるクロマチンの修飾および遺伝子発現の活性化, 領域融合レビュー, Feb. 2018.
• 木村宏, 佐藤優子. 遺伝子発現の理解と制御のための「ヌクレオーム」研究とエピゲノム編集, JATAFFジャーナル, Vol. 7, No. 5, pp. 3－6, Nov. 2017.
• 木村宏, 佐藤優子. ゲノム，エピゲノムからヌクレオームへ：遺伝情報発現制御機構の包括的理解に向けて, 情報管理, 国立研究開発法人 科学技術振興機構, Vol. 60, No. 8, pp. 555-563, 2017.
• Kimura H, Yamagata K, N.Beaujean, H.Jammes, A.Jouneau. Visualization of epigenetic modifications in preimplantation embryos., Nuclear Reprogramming, second edition, (Methods in Molecular Biology ), Humana Press, 2015.
• Hieda M, Matsuura N, Kimura H, M.Verma. Histone Modifications Assosiated with Cancer Cell Migration and Invasion, Cancer Epigenetics - Risk Assessment, Diagnosis, Treatment, and Prognosis, (Methods in Molecular Biology), Humana Press, 2015.
• Kimura H, Sato Y, J. Zhang, C. Schultz. Histone modification sensors in living cells., Optical Probes in Biology, Taylor & Francis Books, Inc., 2015.
• 木村 宏. ヒストンH2A─最も多様性のあるコアヒストン, 実験医学, Vol. 32, pp. pp2087-2091, 2014.
• 佐藤優子, 木村 宏, 畑田出穂, 久保田健夫. エピジェネティクスの生細胞イメージング技術, エピジェネティクス―基礎研究から産業応用への展望―, シーエムシー出版, pp. pp142-160, 2014.
• Hiroshi Kimura. Histone modification for human epigenome analysis., J Hum Genet, Vol. 58, pp. pp439-445, 2013.
• 木村宏, 佐藤優子, 佐々木裕之, 中尾光善, 中島欽一. ヒストン修飾検出法, 遺伝子医学MOOK 25号「エピジェネティクスと病気」, メディカル・ドゥ, Vol. 25, pp. pp247-253, 2013.
• 木村宏, 胡桃坂仁志, 平岡 泰, 原口徳子. ヌクレオソーム, 染色体と細胞核のダイナミクス, 化学同人, pp. pp19-50, 2013.
• 木村 宏, 牛島俊和, 眞貝洋一. ヒストン修飾検出法, エピジェネティクスキーワード事典, 羊土社, pp. pp275-281, 2013.
• 木村宏, 佐藤陽子, 林 陽子. 内在性蛋白質翻訳後修飾の生細胞計測, 生物物理, Vol. 52, pp. pp234-235, 2012.
• Kimura H, Hayashi-Takanaka Y, Yamagata K. Visualization of DNA methylation and histone modifications in living cells., Curr Opin Cell Biol, Vol. 22, pp. pp412-418, 2010.
• 木村宏, 林 陽子. エピゲノム制御にかかわるヒストン修飾のイメージング, 医学のあゆみ, Vol. 235, pp. pp995-1000, 2010.
• 木村宏, 佐藤優子, 林陽子, 牛島俊和, 塩田邦郎, 田嶋正二, 吉田稔. 特異的モノクローナル抗体を用いたメチル化ヒストンダイナミクスの可視化., エピジェネティクスと疾患（実験医学増刊）, 羊土社, pp. pp115-121, 2010.
• 木村宏, 林 陽子, 平岡泰, 原田昌彦, 田代聡. ヒストンダイナミクスの可視化と膜透過化細胞による再構成., 細胞核－遺伝情報制御と疾患：染色体・核輸送のダイナミクスと細胞分化から個体発生，破綻による疾患まで, 羊土社, pp. pp153-158, 2009.
• 木村宏. ビフォー＆アフター フォトブリーチ, 蛋白質核酸酵素, Vol. 53, pp. pp1992-1999, 2008.
• 林陽子, 後藤友二, 木村宏, 牛島俊和, 眞貝洋一. クロマチン免疫沈降法., エピジェネティクス実験プロトコール, 羊土社, pp. pp143-166, 2008.
• 原口徳子, 木村宏, 平岡泰. 生細胞蛍光イメージング, 講義と実習：生細胞蛍光イメージング－阪大・北大顕微鏡コースブック., 共立出版, 2007.
• 木村宏. 光退色と光刺激による細胞内分子動態の解析, 化学と生物, Vol. 45, pp. pp798-804, 2007.
• Kimura H, Cook,P.R., K.Takeyasu, K.Nagata. Structure and function of inner-nuclear architectures., Nuclear Dynamics, Springer-Verlag Tokyo, pp. pp177-195, 2006.
• 木村宏. 機能の頑強性と可塑性を支える細胞核構造., 蛋白質核酸酵素, Vol. 51, pp. PP293-300, 2006.
• 木村宏, 米田悦啓, 五十嵐和彦, 中尾光喜. 細胞核の解析技術：オーバービュー, 細胞核の世界：ダイナミクスから病態まで, 共立出版, pp. pp1970-1971, 2006.
• 木村宏, 米田悦啓, 五十嵐和彦, 中尾光喜. 細胞周期と細胞分裂のダイナミクス：オーバービュー, 細胞核の世界：ダイナミクスから病態まで, 共立出版, pp. pp2115-2116, 2006.
• Hiroshi Kimura. Histone dynamics in living cells revealed by photobleaching, DNA Repair, Vol. 4, pp. pp939-950, 2005.
• 木村宏, 押村光雄, 平岡泰. クロマチンタンパク質のFRAP解析：結合・解離速度の測定, クロマチン・染色体実験プロトコール, 羊土社, pp. pp115-127, 2005.
• 木村宏. フォトブリーチング法による蛍光標識蛋白質の細胞内動態解析法①：固定細胞を用いた条件設定, 実験医学, Vol. 13, pp. pp1739-1745, 2004.
• 木村宏. フォトブリーチング法による蛍光標識蛋白質の細胞内動態解析法②：生細胞における測定と定量的解析のためのアプローチ., 実験医学, Vol. 13, pp. pp1851185, 2004.
• 木村宏, 竹安邦夫, 米田悦啓. 転写の分子イメージング, 細胞核のダイナミクス, シュプリンガーフェアラーク東京, pp. pp23-32, 2004.
• Kimura H, Hieda M, Cook PR. Measuring histone and polymerase dynamics in living cells., Methods Enzymol, Vol. 375, pp. pp381-393, 2004.
• 木村宏. 時間軸にわたる染色体機能の変化., 医学のあゆみ, Vol. 208, pp. pp890-894, 2004.
• 木村宏. クロマチンのダイナミクス, 生体の科学, Vol. 54, pp. pp166-170, 2003.
• 木村宏. 生細胞におけるクロマチンの分子動態と機能, 細胞工学, Vol. 21, pp. pp1147-1153, 2003.
• 木村宏. 細胞核構造と機能のストカスティックな制御, 生物物理, Vol. 43, pp. pp234-239, 2003.
• 木村宏. 四角いスタンプ, 細胞工学, Vol. 22, pp. pp1041, 2003.
• 木村宏, 半田 宏. 転写ファクトリーと核内構造, わかる実験医学シリーズ｢転写がわかる｣, 羊土社, pp. pp99-106, 2002.
• 木村宏. 生細胞におけるクロマチンの可視化, 実験医学別冊｢クローズアップ実験法総集編｣, 羊土社, pp. pp167-172, 2002.
• 木村宏. 生細胞におけるクロマチンの可視化, 実験医学, Vol. 19, pp. pp2313-2317, 2001.
• Pombo A, Jones E, Iborra FJ, Kimura H, Sugaya K, Cook PR, Jackson DA. Specialized transcription factories within mammalian nuclei., Crit Rev Eukaryot Gene Expr, Vol. 10, pp. pp21-29, 2000.

特許など

• 木村宏, 佐藤優子, 大井彰人, 胡桃坂　仁志, 鯨井　智也, 大川　恭行. ヒストンＨ３トリメチル化リシン特異的モノクローナル抗体又はその抗原結合性断片. 特許. 公開. 国立大学法人東京工業大学. 2017/06/06. 特願2017-111580. 2020/08/27. 特開2020-127366. 2020.
• 木村宏, 半田哲也, 佐藤優子, 林　陽子, 大川　恭行　, 原田　哲仁　, 胡桃坂　仁志　. ＤＮＡ結合タンパク質の結合領域の近傍に所望のＤＮＡ断片を挿入する方法. 特許. 登録. 国立大学法人東京工業大学, 国立大学法人九州大学. 2017/05/24. 特願2018-536938. 2019/08/08. 再表2018/042776. 特許第6943376号. 2021/09/13 2021.

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