論文

• Bartlett DA, Dileep V, Handa T, Ohkawa Y, Kimura H, Henikoff S. High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq), J Cell Biol, 220, 12, e202103078, Feb. 2022.
• Uchino S, Ito Y, Sato Y, Handa T, Ohkawa Y, Tokunaga M, Kimura H. Live imaging of transcription sites using an elongating RNA polymerase II-specific probe., J Cell Biol, Vol. 221, No. 2, p. e202104134 (23 pages), Dec. 2021.  公式リンク  
  
• Maehara K, Tomimatsu K, Harada A, Tanaka Kaori, Sato Shoko, Fukuoka M, Okada S, Handa T, Kurumizaka H, Saitoh N, Hiroshi Kimura, Ohkawa Y. Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections, Mol Syst Biol, 17, 11, e10323, Nov. 2021.
• Forero-Quintero LS, Raymond W, Handa T, Saxton MN, Morisaki T, Kimura H, Bertrand E, Munsky B, Stasevich TJ. Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene, Nat Commun, 12, 1, 3158, May 2021.
• Uchino S, Ito Y, Sato Y, Handa T, Yasuyuki Ohkawa, Tokunaga M, Kimura H. Visualizing transcription sites in living cells using a genetically encoded probe specific for the elongating form of RNA polymerase II, bioRxiv, No. 2021.04.27, p. 441582, Apr. 2021.  公式リンク  
  
• Sjoerd J D Tjalsma, Mayako Hori, Yuko Sato, Aurelie Bousard, Akito Ohi, Ana Cláudia Raposo, Julia Roensch, Agnes Le Saux, Jumpei Nogami, Kazumitsu Maehara, Tomoya Kujirai, Tetsuya Handa, Sandra Bagés-Arnal, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Simão Teixeira da Rocha, Jan J Żylicz, Hiroshi Kimura, Edith Heard. H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing, EMBO reports, volume 22, Issue 3, e51989, Mar. 2021.
• Tetsuya Handa, Akihito Harada, Kazumitsu Maehara, Shoko Sato, Masaru Nakao, Naoki Goto, Hitoshi Kurumizaka, Yasuyuki Ohkawa, Hiroshi Kimura. Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input, Nat Protoc, Vol. 15, No. 10, pp. 3334-3360, Aug. 2020.
• K. Yamagata, K. Nagai, H. Miyamoto, M. Anzai, H. Kato, K. Miyamoto, S. Kurosaka, R. Azuma, II Kolodeznikov, A. V. Protopopov, V. V. Plotnikov, H. Kobayashi, R. Kawahara-Miki, T. Kono, M. Uchida, Y. Shibata, T. Handa, Y. Hosoi, T. Mitani, K. Matsumoto, A. Iritani, K. Yamagata, K. Nagai, H. Miyamoto, M. Anzai, H. Kato, K. Miyamoto, S. Kurosaka, R. Azuma, II Kolodeznikov, A. V. Protopopov, V. V. Plotnikov, H. Kobayashi, R. Kawahara-Miki, T. Kono, M. Uchida, Y. Shibata, T. Handa, H. Kimura, Y. Hosoi, T. Mitani, K. Matsumoto, A. Iritani. Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging, Sci Rep, Vol. 9, No. 1, pp. 4050, Mar. 2019.
• Tetsuya Handa, Hiroshi Kimura. A chromatin integration labelling method enables epigenomic profiling with lower input, Nat Cell Biol, Vol. 21, No. 2, pp. 287－296, Dec. 2018.

国際会議発表 (査読有り)

• Satoshi Uchino, Yuma Ito, Jessica Dai, Yuko Sato, Tetsuya Handa, Yasuyuki Ohkawa, Makio Tokunaga, Hiroshi Kimura. Live imaging of the initiation and elongation forms of RNA polymerase II using phosphorylation-specific probes., The 30th Hot Spring Harbor International Symposium(Online), Jan. 2022.

国内会議発表 (査読なし・不明)

• 内野 哲志, 伊藤 由馬, 佐藤 優子, 半田 哲也, 大川 恭行, 徳永 万喜洋, 木村 宏. リン酸化型RNAポリメラーゼII可視化プローブによる転写部位の生細胞観察, 第39回染色体ワークショップ・第20回核ダイナミクス研究会, オンライン, Dec. 2021.
• 内野 哲志, 伊藤 由馬, Jessica Dai, 佐藤 優子, 半田 哲也, 大川 恭行, 徳永 万喜洋, 木村 宏. 転写伸長型RNAポリメラーゼII可視化プローブによる生細胞内における 転写伸長部位の観察, 第44回日本分子生物学会年会, Dec. 2021.
• Yuko Sato, Nguyen Thi Bich Ngoc, Haruka Oda, Tetsuya Handa, Hidenori Nishihara, Akihito Harada, Yasuyuki Ohkawa, Hiroshi Kimura. Spatiotemporal dynamics of histone modifications during zebrafish zygotic genome activation, 第43回日本分子生物学会年会, Dec. 2020.

その他の論文・著書など

• 木村宏, 半田哲也. ヒストン修飾解析の最前線, 遺伝子医学, No. 10, pp. 124－129, Jan. 2020.

特許など

• 木村宏, 半田哲也, 佐藤優子, 林　陽子, 大川　恭行　, 原田　哲仁　, 胡桃坂　仁志　. ＤＮＡ結合タンパク質の結合領域の近傍に所望のＤＮＡ断片を挿入する方法. 特許. 登録. 国立大学法人東京工業大学, 国立大学法人九州大学. 2017/05/24. 特願2018-536938. 2019/08/08. 再表2018/042776. 特許第6943376号. 2021/09/13 2021.

[ BibTeX 形式で保存 ]    [ 論文・著書をCSV形式で保存 ]    [ 特許をCSV形式で保存 ]