論文

• Yohei Kono, Stephen A. Adam, Yuko Sato, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS, J Cell Biol, Vol. 221, No. 12, e202201024, Oct. 2022.
• Kenji Fukushima, Noriko Itaba, Yohei Kono, Shizuma Okazaki, Shinpei Enokida, Naomi Kuranobu, Jun Murakami, Makoto Enokida, Hideki Nagashima, Susumu Kanzaki, Noriyuki Namba, Goshi Shiota. Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice, Regenerative Therapy, Vol. 18, pp. 292-301, Dec. 2021.  公式リンク  
  
• Sakaguchi Takuki, Kono Yohei, Itaba Noriko, Morimoto Minoru, Isomoto Hajime, Shiota Goshi. Identification of a Novel Deactivating Small-Molecule Compound for Fibrogenic Hepatic Stellate Cells, Yonago Acta Medica, Tottori University Medical Press, Vol. 63, No. 1, pp. 79-87, Feb. 2020.
• Noriko Itaba, Yohei Kono, Kaori Watanabe, Tsuyoshi Yokobata, Hiroyuki Oka, Mitsuhiko Osaki, Hiroki Kakuta, Minoru Morimoto, Goshi Shiota. Reversal of established liver fibrosis by IC-2-engineered mesenchymal stem cell sheets, Scientific Reports, Vol. 9, No. 1, May 2019.
• Noriko Itaba, Ikuya Noda, Hiroyuki Oka, Yohei Kono, Kaori Okinaka, Tsuyoshi Yokobata, Shizuma Okazaki, Minoru Morimoto, Goshi Shiota. Hepatic cell sheets engineered from human mesenchymal stem cells with a single small molecule compound IC-2 ameliorate acute liver injury in mice, Regenerative Therapy, Vol. 9, pp. 45-57, Dec. 2018.  公式リンク  
  
• Kenji Oyama, Keita Kanki, Hiroki Shimizu, Yohei Kono, Junya Azumi, Kan Toriguchi, Etsuro Hatano, Goshi Shiota. Impact of Preferentially Expressed Antigen of Melanoma on the Prognosis of Hepatocellular Carcinoma, Gastrointestinal Tumors, Vol. 3, No. 3-4, pp. 128-135, Aug. 2016.
• Noriko Itaba, Tomohiko Sakabe, Keita Kanki, Junya Azumi, Hiroki Shimizu, Yohei Kono, Yoshiaki Matsumi, Ken-ichiro Abe, Takayuki Tonoi, Hiroyuki Oka, Toshihiko Sakurai, Hiroyuki Saimoto, Minoru Morimoto, Yo Mabuchi, Yumi Matsuzaki, Goshi Shiota. Identification of the small molecule compound which induces hepatic differentiation of human mesenchymal stem cells, Regenerative Therapy, Vol. 2, pp. 32-41, Dec. 2015.
• Itaba Noriko, Matsumi Yoshiaki, Okinaka Kaori, Ashla An Afida, Kono Yohei, Osaki Mitsuhiko, Morimoto Minoru, Sugiyama Naoyuki, Ohashi Kazuo, Okano Teruo, Shiota Goshi. Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice, Scientific Reports, Nature Publishing Group, Vol. 5, No. 1, Oct. 2015.
• Noriko Itaba, Peninah M. Wairagu, Natsumi Aramaki, Toshihiro Yasui, Yoshiaki Matsumi, Yohei Kono, Ai N.H. Phan, Makoto Otsu, Takahiro Kunisada, Yukio Nakamura, Hideyuki Okano, Yangsik Jeong, Goshi Shiota. Nuclear receptor gene alteration in human induced pluripotent stem cells with hepatic differentiation propensity, Hepatology Research, Vol. 44, No. 14, pp. E408-E419, May 2014.
• Remina Ikeda, Kyoko Ishii, Yoshiko Hoshikawa, Junya Azumi, Yuta Arakaki, Toshihiro Yasui, Shizuka Matsuura, Yoshiaki Matsumi, Yohei Kono, Yusuke Mizuta, Akihiro Kurimasa, Ichiro Hisatome, Scott L. Friedman, Hironaka Kawasaki, Goshi Shiota. Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation, Inflammation Research, Vol. 60, No. 6, pp. 597-604, Feb. 2011.

著書

• 汐田剛史, 河野洋平, 板場則子, 土谷博之. 第3章 肝障害を来す成因と障害機序をおさえる「３．代謝性肝疾患」, 月刊薬事, 株式会社じほう, Vol. 62, No. 2, pp. 112-117, Jan. 2020.
• 河野洋平, 汐田剛史. 海外文献紹介「マウス成体内においてCas9によるゲノム編集が疾患の変異および表現型を修正する」, 日本再生医療学会雑誌 再生医療, メディカルレビュー社, Vol. 13, No. 4, pp. 78, Nov. 2014.

国際会議発表 (査読有り)

• Yohei Kono, Noriko Itaba, Goshi Shiota. Regenerative therapy for liver fibrosis using IC-2-engineered mesenchymal stem cell sheets, The 8th Meeting of the International Federation for Artificial Organs, Nov. 2019.
• Yohei Kono, Noriko Itaba, Peninah M. Wairagu, Ai N.H. Phan, Yuki Kayahara, Yangsik Jeong, Goshi Shiota. Nuclear receptor gene expression during hepatic differentiation from human induced pluripotent stem cells with hepatic differentiation propensity, The 18th Takeda Science Foundation Symposium on Bioscience, Jan. 2015.

その他の論文・著書など

• Yohei Kono, Stephen A. Adam, Karen L. Reddy, Yixian Zheng, Ohad Medalia, Robert D. Goldman, Hiroshi Kimura, Takeshi Shimi. Nucleoplasmic Lamin C Rapidly Accumulates at Sites of Nuclear Envelope Rupture with BAF and cGAS, Jan. 2022.  公式リンク  
  

研究ハイライト

• 河野洋平, 志見剛, 佐藤優子, 木村宏. 動物細胞の核膜における核膜孔複合体とラミンの結合の定量解析に成功 心筋症などの遺伝病における細胞病態の解明への一歩. 2022～2022.

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