@article{CTT100714121, author = {Faizah Noor and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil–Globule Transition Behavior}, journal = {Bioconjugate Chemistry}, year = 2016, } @article{CTT100752062, author = {H. Hino and M. Kamiya and K. Kitano and K. Mizuno and S. Tanaka and N. Nishiyama and K. Kataoka and Y. Urano and J. Nakajima}, title = {Rapid cancer fluorescence imaging using a γ-glutamyltranspeptidase-specific probe for primary lung cancer}, journal = {Translational Oncology}, year = 2016, } @article{CTT100752053, author = {M. Iijima and D. Ulkoski and S. Sakuma and D. Matsukuma and N. Nishiyama and H. Otsuka and C. Scholz}, title = {Synthesis of PEGylated poly(amino acid) pentablock copolymers and their self-assembly}, journal = {Polymer International}, year = 2016, } @article{CTT100714252, author = {Nobuhiro Nishiyama and Yasuhiro Matsumura and Kazunori Kataoka}, title = {Development of polymeric micelles for targeting intractable cancers.}, journal = {Cancer science}, year = 2016, } @article{CTT100714250, author = {Peng Mi and Daisuke Kokuryo and Cabral Horacio and Hailiang Wu and Yasuko Terada and Tsuneo Saga and Ichio Aoki and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy}, journal = {Nature Nanotechnology}, year = 2016, } @article{CTT100714253, author = {Yoko Matsumoto and Miyamoto Yuichiro and Cabral Horacio and Yu Mastumoto and Kazunori Nagasawa and Shunsuke Nakagawa and Tetsu Yano and Daichi Maeda and Katsutoshi Oda and Kei Kawana and Nobuhiro Nishiyama and Kazunori Kataoka and Tomoyuki Fujii}, title = {Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132}, journal = {Cancer Science}, year = 2016, } @article{CTT100723937, author = {Takahiro Nomoto and Shigeto Fukushima and Michiaki Kumagai and Kozo Miyazaki and Aki Inoue and Peng Mi and Yoshinori Maeda and Kazuko Toh and Yu Mastumoto and Yuji Morimoto and Akihiro Kishimura and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy.}, journal = {Biomaterials science}, year = 2016, } @article{CTT100714260, author = {Haruka Nishida and Yoko Matsumoto and Kei Kawana and Christie James and Mitsuru Naito and Kim Beob Soo and Kazuko Toh and Hyun Su Min and Yi Yu and Yu Mastumoto and Hyun Jin Kim and Kanjiro Miyata and Ayumi Taguchi and Kensuke Tomio and Aki Yamashita and Tomoko Inoue and Hiroe Nakamura and Asaha Fujimoto and Masakazu Sato and Mitsuyo Yoshida and Katsuyuki Adachi and Takahide Arimoto and Osamu Wada-Hiraike and Katsutoshi Oda and Takeshi Nagamatsu and Nobuhiro Nishiyama and Kazunori Kataoka and Yutaka Osuga and Tomoyuki Fujii}, title = {Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes}, journal = {Journal of Controlled Release}, year = 2016, } @article{CTT100720773, author = {Kotaro Hayashi and Hiroyuki Chaya and Shigeto Fukushima and Sumiyo Watanabe and Hiroyasu Takemoto and Kensuke Osada and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers}, journal = {Macromolecular Rapid Communications}, year = 2016, } @article{CTT100720774, author = {Kotaro Hayashi and Hiroyuki Chaya and Shigeto Fukushima and Sumiyo Watanabe and Hiroyasu Takemoto and Kensuke Osada and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Macromol. Rapid Commun. 6/2016.}, journal = {Macromolecular rapid communications}, year = 2016, } @article{CTT100714258, author = {Hirokuni Uchida and Keiji Itaka and Satoshi Uchida and Takehiko Ishii and Tomoya Suma and Kanjiro Miyata and Makoto Oba and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure}, journal = {Journal of the American Chemical Society}, year = 2016, } @inproceedings{CTT100752174, author = {Nobuhiro Nishiyama}, title = {evelopment of supramolecular nanodevices for cancer diagnostics and therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100752147, author = {Chihhao Huang and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {2-nitrobenzensulfonamide groups as a chemical linker with enhanced extracellular stability and redox-sensitive cleavability for siRNA-conjugated polymer system}, booktitle = {}, year = 2016, } @inproceedings{CTT100752148, author = {Faizah Noor and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {Artificial control of siRNA bioactivity based on the phase transition behavior of the conjugated polymeric molecule}, booktitle = {}, year = 2016, } @inproceedings{CTT100752141, author = {Hiroyasu Takemoto and Kanjiro Miyata and Kotaro Hayashi and Yuki Mochida and Kazunori Kataoka and Nobuhiro Nishiyama}, title = {シロキサンネットワークにて形成されるsiRNA内包有機-無機ハイブリッドナノ粒子の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752175, author = {Nobuhiro Nishiyama}, title = {Challenge to new generation micellar nanocarriers}, booktitle = {}, year = 2016, } @inproceedings{CTT100752166, author = {Nobuhiro Nishiyama}, title = {精密合成高分子材料を基盤する がん診断・治療ナノマシンの創製}, booktitle = {}, year = 2016, } @inproceedings{CTT100752144, author = {Naoki Yamada and Yuto Honda and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Novel glutamine-based polymeric ligand for transporter-mediated tumor targeting}, booktitle = {}, year = 2016, } @inproceedings{CTT100752143, author = {越後真梨那 and Hiroyasu Takemoto and Kotaro Hayashi and Kanjiro Miyata and 金澤秀子 and Kazunori Kataoka and Nobuhiro Nishiyama}, title = {がん細胞内にて特異的に切断される Linker を利用した siRNA 送達キャリアの開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752163, author = {Nobuhiro Nishiyama}, title = {高分子ナノテクノロジーを基盤とした革新的ナノ診断・治療システムの開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752164, author = {Nobuhiro Nishiyama}, title = {精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製}, booktitle = {}, year = 2016, } @inproceedings{CTT100752131, author = {Faizah Noor and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {Development of siRNA-conjugated polymer with coil-globule transition behavior for an artificially controlled gene silencing activity}, booktitle = {}, year = 2016, } @inproceedings{CTT100752139, author = {Xiaohang Sun and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {がんへの薬剤の集積状態をレポートするナノメディシンの開 発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752136, author = {Junhyun Kim and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {高分子ミセルにおける内核構造の安定性の差異がもたらす腫瘍集積性に関する考察}, booktitle = {}, year = 2016, } @inproceedings{CTT100752135, author = {Chih Ling Wang and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {A Novel Design of Polyion Complex (PIC) with The Pyruvate-Reactive Function toward Enhanced Cytosolic Release of siRNA}, booktitle = {}, year = 2016, } @inproceedings{CTT100752160, author = {Nobuhiro Nishiyama}, title = {がんの標的治療のための高分子ミセル型薬物送達システムの開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752158, author = {Nobuhiro Nishiyama}, title = {高分子ナノテクノロジーを基盤とする革新的がん診断・治療システムの創出}, booktitle = {}, year = 2016, } @inproceedings{CTT100752157, author = {Nobuhiro Nishiyama}, title = {高分子ミセル型ナノ医薬品の開発-アカデミアからの取り組み-}, booktitle = {}, year = 2016, } @inproceedings{CTT100752162, author = {Nobuhiro Nishiyama}, title = {高分子ナノテクノロジーを基盤とした革新的DDSの開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752130, author = {NOOR and Hiroyasu Takemoto and Takahiro Nomoto and Nobuhiro Nishiyama}, title = {Development of thermoresponsive polymer-siRNA conjugates for controlled RNAi activity}, booktitle = {}, year = 2016, } @inproceedings{CTT100752128, author = {Chih-Ling and Hiroyasu Takemoto and Nobuhiro Nishiyama}, title = {Programmed siRNA Release based on α-Oxohydrazone Chemistry for Polyion complex-based siRNA Delivery System}, booktitle = {}, year = 2016, } @inproceedings{CTT100752153, author = {Nobuhiro Nishiyama}, title = {高分子ミセル型ナノマシンが拓く未来医療}, booktitle = {}, year = 2016, } @inproceedings{CTT100752156, author = {Nobuhiro Nishiyama}, title = {高分子ナノテクノロジーを基盤とする革新的ナノメディシンの創製}, booktitle = {}, year = 2016, } @inproceedings{CTT100752176, author = {Nobuhiro Nishiyama}, title = {Development of supramolecular nanodevices for cancer diagnosis and therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100752151, author = {Nobuhiro Nishiyama}, title = {高分子ナノテクノロジーを基盤とした革新的核酸医薬シーズ送達システムの創出}, booktitle = {}, year = 2016, } @inproceedings{CTT100752178, author = {Nobuhiro Nishiyama and Horacio Cabral}, title = {Development of supramolecular nanomedicines for cancer diagnosis and therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100752179, author = {Nobuhiro Nishiyama}, title = {Development of supramolecular nanodevices for cancer diagnosis and therapy}, booktitle = {}, year = 2016, } @misc{CTT100752031, author = {P. Mi and F. Wang and N. Nishiyama and H. Cabral}, title = {Molecular cancer imaging with polymeric nanoassemblies: from tumor detection to theranostics}, year = 2016, } @misc{CTT100761475, author = {Nobuhiro Nishiyama and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui}, title = {結合体}, howpublished = {PublishedPatent}, year = 2017, month = {}, note = {特願2016-113664(2016/06/07), 特開2017-218408(2017/12/14)} }