@book{CTT100705281, author = {田中健 and 中村浩之 and 岩本武明 and 斎藤雅一 and 柴田高範 and 長澤和夫 and 西林仁昭}, title = {ウェイド「有機化学」問題の解き方}, publisher = {丸善}, year = 2016, } @article{CTT100741946, author = {G. Dormán and H. Nakamura and A. Pulsipher and G. D. Prestwich}, title = {The Life of Pi Star: Exploring the Exciting and Forbidden Worlds of the Benzophenone Photophore}, journal = {Chem. Rev.}, year = 2016, } @article{CTT100734669, author = {S. Fuse and T. Ohuchi and Y. Asawa and S. Sato and H. Nakamura}, title = {Development of 1-Aryl-3-furanyl/Thienyl-imidazopyridine Templates for Inhibitors against Hypoxia Inducible Factor (HIF)-1 Transcriptional Activity}, journal = {Bioorganic and Medicinal Chemistry Letters}, year = 2016, } @article{CTT100734541, author = {Y. Mifune and H. Nakamura and S. Fuse}, title = {A Rapid and Clean Synthetic Approach to Cyclic Peptides via Micro-flow Peptide Chain Elongation and Photochemical Cyclization: Synthesis of a Cyclic RGD Peptide}, journal = {Organic & Biomolecular Chemistry}, year = 2016, } @article{CTT100734523, author = {Shinichiro Fuse and Yuto Mifune and Hiroyuki Nakamura and Hiroshi Tanaka}, title = {Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation}, journal = {Nature Communications}, year = 2016, } @article{CTT100828139, author = {T. Morita and S. Fuse and H. Nakamura}, title = {Generation of 4-Isoxazolyl Anion Species: Facile Access to 4-Substituted Isoxazoles}, journal = {Angewandte Chemie International Edition}, year = 2016, } @article{CTT100828138, author = {T. Morita and S. Fuse and H. Nakamura}, title = {Generation of 4-Isoxazolyl Anion Species: Facile Access to 4-Substituted Isoxazoles}, journal = {Angewandte Chemie International Edition}, year = 2016, } @article{CTT100718516, author = {Shunsuke Kikuchi and Daisuke Kanoh and Shinichi Sato and Yoshinori Sakurai and Minoru Suzuki and Hiroyuki Nakamura}, title = {Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy}, journal = {Journal of Controlled Release}, year = 2016, } @article{CTT100774134, author = {Shunsuke Kikuchi and Daisuke Kanoh and Shinichi Sato and Yoshinori Sakurai and Minoru Suzuki and Hiroyuki Nakamura}, title = {Maleimide-Functionalized closo-Dodecaborate Albumin Conjugates (MID-AC): The Unique Ligation at both Cysteine and Lysine Residues Enabling to Efficient Boron Delivery to Tumor for Neutron Capture Therapy}, journal = {J. CONTROL. RELEASE}, year = 2016, } @article{CTT100718515, author = {Guangzhe Li and Hiroyuki Nakamura}, title = {Synthesis of 2-Indolyltetrahydroquinolines by Zinc (II)-Catalyzed Intramolecular Hydroarylation-Redox Cross-Dehydrogenative Coupling of N-Propargylanilines with Indoles}, journal = {Angewandte Chemie International Edition}, year = 2016, } @article{CTT100718514, author = {Masao Sasai and Hiroyuki Nakamura and Nagao Sougawa and Yoshinori Sakurai and Minoru Suzuki and Chun Man Lee}, title = {Novel Hyaluronan Formulation Enhances the Efficacy of Boron Neutron Capture Therapy for Murine Mesothelioma}, journal = {Anticancer research}, year = 2016, } @article{CTT100718513, author = {Hyun Seung Ban and Yoshikazu Uto and Misun Won and Hiroyuki Nakamura}, title = {Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015)}, journal = {Expert opinion on therapeutic patents}, year = 2016, } @article{CTT100705305, author = {Hiroyuki Nakamura and M Yamauchi and N Honda and H Hazama and S Tachikawa and K Awazu}, title = {Effective Photodynamic Therapy in Drug-Resistant Prostate Cancer Cells Utilizing a Non-Viral Antitumor Vector}, journal = {Laser Therapy}, year = 2016, } @inproceedings{CTT100823012, author = {佐藤伸一 and 中村公亮 and 中村浩之}, title = {酵素Horseradish Peroxidaseを利用したタンパク質化学修飾}, booktitle = {}, year = 2016, } @inproceedings{CTT100823013, author = {中村浩之}, title = {世界をリードする次世代低侵襲がん治療:中性子捕捉療法}, booktitle = {}, year = 2016, } @inproceedings{CTT100734629, author = {石井秀一 and 布施新一郎 and 佐藤伸一 and 中野洋文 and 中村浩之}, title = {天然物タンシノンIIAを基盤とした新規HIF-1α阻害剤の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100823011, author = {中村浩之}, title = {生体高分子を用いたホウ素デリバリーシステムの構築}, booktitle = {}, year = 2016, } @inproceedings{CTT100734181, author = {小竹佑磨 and 中村浩之 and 布施新一郎}, title = {マイクロフロー合成法を駆使するN-メチル化ペプチドの合成法開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100733983, author = {石井秀一 and 布施新一郎 and 佐藤伸一 and 中野洋文 and 中村浩之}, title = {天然物タンシノンIIAを基盤とした新規HIF-1α阻害剤の開発研究}, booktitle = {}, year = 2016, } @inproceedings{CTT100823010, author = {Hiroyuki Nakamura and Kikuchi and Daisuke Kanoh and Shinichi Sato and Yoshinori Sakurai and Minoru Suzuki}, title = {Maleimide-Functionalized closo-Dodecaborate Albumin Conjugate: Unique Ligation at Cysteine and Lysine Residues Enables Efficient Boron Delivery to Tumor for Neutron Capture Therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100823009, author = {中村浩之}, title = {リポソーム包埋型およびアルブミン結合型ホウ素キャリアー}, booktitle = {}, year = 2016, } @inproceedings{CTT100734360, author = {S. Fuse and Y. Mifune and H. Nakamura and H. Tanaka}, title = {Total Synthesis of Feglymycin based on a Linear/Convergent Hybrid Approach using Micro-flow Amide Bond Formation}, booktitle = {}, year = 2016, } @inproceedings{CTT100734182, author = {石井秀一 and 布施新一郎 and 中村浩之}, title = {多環性オルトキノン化合物の短段階合成を志向したPd触媒による脱水素型環化反応の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100823008, author = {中村浩之}, title = {中性子捕捉療法用ホウ素高集積リポソームの開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100823005, author = {Hiroyuki Nakamura}, title = {Enhanced Permeability and Retention (EPR) Effect-Based Efficient Boron Delivery Systems for BNCT}, booktitle = {}, year = 2016, } @inproceedings{CTT100823006, author = {S. Ishii and S. Kikuchi and S. Sato and H. Nakamura}, title = {Development of closo-Dodecaborate-Serum Albumin Conjugates via Ruthenium-Photocatalyzed Tyrosine Modification for Neutron Capture Therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100727127, author = {稲井瑞穂 and 古山祐 and 洪暎淳 and 本多典広 and 間久直 and 布施新一郎 and 中村浩之 and 金田安史 and 粟津邦男}, title = {複製能欠損ウイルス粒子を用いた光感受性薬剤の細胞内局在と腫瘍選択性の検討}, booktitle = {}, year = 2016, } @inproceedings{CTT100823007, author = {中村浩之}, title = {化学でがんの根治に挑む}, booktitle = {}, year = 2016, } @inproceedings{CTT100715879, author = {盛田大輝 and 布施新一郎 and 中村浩之}, title = {4-イソオキサゾリルアニオンを利用したイソオキサゾール4位の官能基化}, booktitle = {}, year = 2016, } @inproceedings{CTT100720037, author = {Hiroyuki Nakamura}, title = {Zinc(II)-Catalyzed Intramolecular Hydroarylation-Redox Cross-Dehydrogenative Coupling of Propargylic Amines}, booktitle = {}, year = 2016, } @inproceedings{CTT100720041, author = {中村浩之}, title = {Boron compounds suitable for BNCT}, booktitle = {}, year = 2016, } @inproceedings{CTT100720291, author = {洪暎淳 and 稲井瑞穂 and 古山祐 and 本多典広 and 間久直 and 布施新一郎 and 中村浩之 and 金田安史 and 粟津邦男}, title = {抗がん剤耐性前立腺がん細胞への迅速な薬剤輸送に向けた複製能欠損ウイルス粒子への光感受性物質の封入}, booktitle = {電気学会 光・量子デバイス研究会}, year = 2016, } @inproceedings{CTT100823001, author = {大西宏明 and 大塚弘毅 and 松島早月 and 渡邊卓 and 中村浩之 and 広川貴次}, title = {蛋白質立体構造解析と分子動力学に基づくEGFR分子標的薬の効果予測}, booktitle = {}, year = 2016, } @inproceedings{CTT100823002, author = {Hiroyuki Nakamura and Kikuchi and Daisuke Kanoh and Shinichi Sato and Yoshinori Sakurai and Minoru Suzuki}, title = {Maleimide-Functionalized closo-Dodecaborate Albumin Conjugates: Unique Ligation at Cysteine and Lysine Residues Enables Efficient Boron Delivery to Tumor for Neutron Capture Therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100823003, author = {佐藤伸一 and 中村公亮 and 中村浩之}, title = {Horseradish Peroxidaseを触媒として利用したタンパク質チロシン残基ラベル化反応}, booktitle = {}, year = 2016, } @inproceedings{CTT100823004, author = {佐藤伸一 and 中村公亮 and 中村浩之}, title = {生体内ヘムの鉄酸化状態変化を利用したタンパク質ラベリング}, booktitle = {}, year = 2016, } @inproceedings{CTT100722307, author = {Syifa Asatyas and 林智広 and 望月誠仁 and 佐藤伸一 and 中村浩之}, title = {顕微ラマン分光イメージング法による単一細胞中のホウ素化合物の濃度分布の可視化}, booktitle = {第13回日本中性子捕捉療法学会学術大会}, year = 2016, } @inproceedings{CTT100823000, author = {中村浩之}, title = {化学でがんを克服できるか?}, booktitle = {}, year = 2016, } @inproceedings{CTT100822999, author = {佐藤伸一 and 菊地俊介 and 石井里武 and 中村浩之}, title = {新規ホウ素キャリアを指向したホウ素修飾アルブミンの開発―ホウ素クラスター共役マレイミドの利用―}, booktitle = {第13回日本中性子捕捉療法学会学術大会}, year = 2016, } @inproceedings{CTT100822998, author = {石井里武 and 菊地俊介 and 佐藤伸一 and 中村浩之}, title = {新規ホウ素キャリアを指向したホウ素修飾アルブミンの開発―チロシン残基修飾法の利用}, booktitle = {}, year = 2016, } @inproceedings{CTT100712717, author = {Taiki Morita and Shinichiro Fuse and Hiroyuki Nakamura}, title = {Preparation of 4-isoxazolyl Grignard reagent and its application for divergent synthesis of 4-substituted isoxazoles}, booktitle = {}, year = 2016, } @inproceedings{CTT100822997, author = {S. Sato and K. Morita and H. Nakamura}, title = {Protein modification using ligand-directed Ru(bpy)3 photocatalysts,}, booktitle = {}, year = 2016, } @inproceedings{CTT100822996, author = {中村浩之 and 佐藤伸一}, title = {タンパク質化学修飾法のパラダイムシフト}, booktitle = {}, year = 2016, } @inproceedings{CTT100709162, author = {滝沢美織 and 布施新一郎 and 中村浩之}, title = {有機D-π-A色素の構造-PDT活性相関の解明}, booktitle = {}, year = 2016, } @inproceedings{CTT100708114, author = {稲葉恵 and 峯岸秀充 and 佐藤伸一 and 布施新一郎 and 中村浩之}, title = {ベンゾフロピラゾール類縁体の設計、合成およびHIF-1阻害能評価}, booktitle = {}, year = 2016, } @inproceedings{CTT100709164, author = {洪暎淳 and 稲井瑞穂 and 本多典広 and 間久直 and 布施新一郎 and 中村浩之 and 金田安史 and 粟津邦男}, title = {迅速な薬剤輸送に向けた複製能欠損センダイウイルス粒子への光感受性物質の封入条件の検討}, booktitle = {}, year = 2016, } @inproceedings{CTT100709163, author = {古山祐 and 稲井瑞穂 and 本多典広 and 間久直 and 布施新一郎 and 中村浩之 and 金田安史 and 粟津邦男}, title = {複製能欠損ウィルス粒子とプロトポルフィリンIV脂質を利用したPDT過程のタイムラプス撮影による作用機序の検討}, booktitle = {}, year = 2016, } @inproceedings{CTT100822990, author = {羽田野兼資 and 佐藤伸一 and 中村浩之}, title = {Ru(bpy)3触媒によるチロシン残基修飾法の分子機構の解明研究}, booktitle = {}, year = 2016, } @inproceedings{CTT100822991, author = {佐藤 伸一 and 中村 公亮 and 中村 浩之}, title = {Horseradish Peroxidaseを触媒としたチロシン残基選択的なタンパク質ラベル化反応}, booktitle = {}, year = 2016, } @inproceedings{CTT100822992, author = {對馬 理彦 and 佐藤 伸一 and 中村 浩之}, title = {ビーズ固相表面における一電子酸化的なタンパク質修飾法の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100822993, author = {布施新一郎 and 滝沢美織 and 中村浩之}, title = {新規PDT用有機色素の開発を志向したD-π-A色素の迅速合成と機能評価}, booktitle = {}, year = 2016, } @inproceedings{CTT100822995, author = {中村浩之 and 立川将士 and 平松亮 and 川端信司 and 黒岩敏彦}, title = {ホウ素クラスター含有水溶性プロトポルフィリン誘導体の合成とPDT効果}, booktitle = {}, year = 2016, } @inproceedings{CTT100709161, author = {布施新一郎 and 滝沢美織 and 中村浩之}, title = {新規PDT用有機色素の開発を志向したD-π-A色素の迅速合成と機能評価}, booktitle = {}, year = 2016, } @inproceedings{CTT100822988, author = {佐藤 伸一 and 中村 公亮 and 中村 浩之}, title = {活性化ヘム検出に立脚した活性酸素誘導性細胞死の評価系開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100708308, author = {松村圭介 and 吉崎聡一 and 米谷真人 and 和田雄二 and 尾込裕平 and 早瀬修二 and 海宝龍夫 and 布施新一郎 and 田中浩士 and 中村浩之 and 高橋孝志}, title = {化学選択的ワンポット連結反応を駆使した色素増感太陽電池用DπA色素の効率的合成法の開発とその機能評価}, booktitle = {}, year = 2016, } @inproceedings{CTT100720044, author = {中村浩之}, title = {Identification and Modification of Target Protein using Small Molecules with Light}, booktitle = {}, year = 2016, } @inproceedings{CTT100720042, author = {中村浩之}, title = {Development of Boron Delivery Nano Vehicles for Neutron Capture Therapy of Cancers}, booktitle = {}, year = 2016, } @inproceedings{CTT100822989, author = {稲葉 恵 and 峯岸 秀充 and 佐藤 伸一 and 中村 浩之}, title = {ベンゾフロピラゾール類縁体の設計、合成およびHIF-1阻害能評価}, booktitle = {}, year = 2016, } @inproceedings{CTT100703101, author = {御舩悠人 and 田中浩士 and 中村浩之 and 布施新一郎}, title = {マイクロフローアミド結合形成法を基盤とするフェグリマイシンの全合成}, booktitle = {}, year = 2016, } @inproceedings{CTT100823267, author = {北村 捷 and 京極 信輔 and Manjusha Joshi and 中村 浩之 and 岩田 耕一}, title = {ピコ秒時間分解けい光分光法で観測された単一成分脂質二重膜における不均一構造}, booktitle = {}, year = 2016, } @inproceedings{CTT100823266, author = {佐藤 伸一 and 中村 公亮 and 中村 浩之 and }, title = {ルミノール誘導体を用いたチロシン残基選択的な化学修飾法開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100823265, author = {羽田野 兼資 and 佐藤 伸一 and 中村 浩之}, title = {光触媒を用いたTyr残基修飾反応における一電子移動範囲の解明}, booktitle = {}, year = 2016, } @inproceedings{CTT100823264, author = {佐藤 伸一 and 中村 公亮 and 中野 洋文 and 中村 浩之}, title = {チロシン残基選択的化学修飾法を用いたチロシンホスファターゼ活性スクリーニング法の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100718508, author = {稲葉 恵 and 峯岸 秀充 and 布施 新一郎 and 中村 浩之}, title = {ベンゾフロピラゾール骨格をもつ 新規HIF-1阻害剤の開発研究}, booktitle = {}, year = 2016, } @inproceedings{CTT100720050, author = {Hiroyuki Nakamura}, title = {Development of Efficient Boron Delivery Nano Carriers for Neutron Capture Therapy}, booktitle = {}, year = 2016, } @inproceedings{CTT100720046, author = {中村浩之}, title = {外部エネルギーと局所増感型ナノデバイスによる低侵襲がん治療}, booktitle = {}, year = 2016, } @inproceedings{CTT100823262, author = {S. Sato and H. Nakamura}, title = {Heme-Catalyzed Tyrosine Click Reaction}, booktitle = {}, year = 2016, } @inproceedings{CTT100823263, author = {佐藤伸一 and 中村公亮 and 中村浩之}, title = {ヘムを触媒とする酸化的チロシン修飾法開発とその応用}, booktitle = {}, year = 2016, } @inproceedings{CTT100700897, author = {中村浩之 and 佐藤伸一 and 立川将士 and 布施新一郎 and 間久直 and 粟津邦男 and 金田安史}, title = {光感受性ポルフィリン脂質の開発とナノ粒子化による光線力学的治療効果}, booktitle = {}, year = 2016, } @inproceedings{CTT100705343, author = {中村浩之}, title = {ホウ素を使ってがんに挑む 〜ホウ素創薬の最前線〜}, booktitle = {}, year = 2016, } @inproceedings{CTT100705334, author = {中村浩之}, title = {外部エネルギーと局所増感型ナノデバイスによる低侵襲がん治療}, booktitle = {}, year = 2016, } @misc{CTT100770810, author = {中村浩之 and 伊東 忍  and 吉岡 正人 }, title = {新規トコフェリルアスコルビン酸誘導体とその製造方法}, howpublished = {公開特許}, year = 2018, month = {}, note = {特願2016-212132(2016/10/28), 特開2018-070509(2018/05/10)} } @misc{CTT100785207, author = {佐藤伸一 and 中村浩之 and 中野 洋文}, title = {チロシンホスファターゼ及びチロシンキナーゼ活性の測定方法}, howpublished = {登録特許}, year = 2020, month = {}, note = {特願2017-544450(2016/09/26), 特開(再表)2017/061288(2018/09/06), 特許第6770750号(2020/09/30)} } @misc{CTT100808478, author = {中村浩之}, title = {ホウ素含有化合物とタンパク質とのコンジュゲートを含む医薬組成物}, howpublished = {登録特許}, year = 2020, month = {}, note = {特願2017-534171(2016/07/26), 再表2017/026276(2018/05/24), 特許第6788278号(2020/11/04)} } @misc{CTT100736999, author = {中村浩之 and 峯岸 秀充}, title = {ベンゾフロピラゾール誘導体}, howpublished = {公開特許}, year = 2016, month = {}, note = {特願2015-092606(2015/04/30), 特開2016-210687(2016/12/15)} } @misc{CTT100713470, author = {佐藤伸一 and 中村浩之}, title = {チロシンの修飾方法}, howpublished = {登録特許}, year = 2019, month = {}, note = {特願2014-246487(2014/12/05), 特開2016-108266(2016/06/20), 特許第6598286号(2019/10/11)} }