@book{CTT100874643, author = {堤 浩 and 三原 久和}, title = {薬剤−ペプチドコンジュゲートとペプチド創薬}, publisher = {化学同人}, year = 2021, } @book{CTT100773788, author = {堤 浩 and 三原久和}, title = {化学修飾ペプチドファージライブラリの構築と標的タンパク質に対するリガンドスクリーニング}, publisher = {技術情報協会}, year = 2017, } @book{CTT100773787, author = {堤 浩 and 三原久和}, title = {ペプチド立体構造の設計と機能}, publisher = {シーエムシー出版}, year = 2017, } @book{CTT100785178, author = {堤浩 and 三原久和}, title = {自己組織化現象を利用したペプチド性足場材料の開発}, publisher = {}, year = 2016, } @book{CTT100785179, author = {堤浩 and 三原久和}, title = {生体分子解析・細胞解析に向けた設計ペプチドチップ}, publisher = {}, year = 2015, } @book{CTT100785180, author = {堤浩 and 築地真也 and 浜地格}, title = {天然酵素の特異的修飾}, publisher = {}, year = 2010, } @book{CTT100785181, author = {堤浩 and 濱崎啓太}, title = {シクロデキストリン-ペプチドハイブリッド}, publisher = {}, year = 2005, } @article{CTT100874479, author = {Jyh Yea Chia and Takayuki Miki and Hisakazu Mihara and Hiroshi Tsutsumi}, title = {Biofunctional supramolecular hydrogels fabricated from a short self-assembling peptide modified with bioactive sequences for the 3D culture of breast cancer MCF-7 cells}, journal = {Bioorganic & Medicinal Chemistry}, year = 2021, } @article{CTT100852347, author = {Takayuki Miki and Taichi Nakai and Masahiro Hashimoto and Keigo Kajiwara and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Intracellular artificial supramolecules based on de novo designed Y15 peptides}, journal = {Nature Communications}, year = 2021, } @article{CTT100852348, author = {Hiroshi Tsutsumi and Kunifumi Tanaka and Jyh Yea Chia and Hisakazu Mihara}, title = {Short self‐assembling peptides with a urea bond: A new type of supramolecular peptide hydrogel materials}, journal = {Peptide Science}, year = 2021, } @article{CTT100856132, author = {Masahiro Hashimoto and Takayuki Miki and Iou Ven Chang and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Selection of fluorescent biosensors against galectin-3 from an NBD-modified phage library displaying designed α-helical peptides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2021, } @article{CTT100837820, author = {Teerapat Anananuchatkul and Hiroshi Tsutsumi and Takayuki Miki and Hisakazu Mihara.}, title = {hDM2 Protein-Binding Peptides Screened from Stapled alpha-Helical Peptide Phage Display Libraries with Different Types of Staple Linkers.}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2020, } @article{CTT100837826, author = {H. Tsutsumi and D. Matsubara and H. Mihara.}, title = {Functionalization of Self-assembling Peptide Materials Using Molecular Recognition of Supramolecular Peptide Nanofibers.}, journal = {Polymer Journal}, year = 2020, } @article{CTT100835142, author = {Teerapat Anananuchatkul and Iou Ven Chang and Takayuki Miki and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Construction of a Stapled α‑Helix Peptide Library Displayed on Phage for the Screening of Galectin-3-Binding Peptide Ligands}, journal = {ACS Omega}, year = 2020, } @article{CTT100809767, author = {Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Self-Assembling Peptides as Building Blocks of Functional Materials for Biomedical Applications.}, journal = {Bulletin of the Chemical Society of Japan}, year = 2019, } @article{CTT100773785, author = {H.Tsutsumi and M. Kawamura and H. Mihara}, title = {Osteoblastic Differentiation on Hydrogels Fabricated from Ca2+-Responsive Self-Assembling Peptides Functionalized with Bioactive Peptides}, journal = {Bioorganic & Medicinal Chemistry}, year = 2018, } @article{CTT100773753, author = {H.Tsutsumi and T. Shirai and H. Ohkusa and H. Mihara}, title = {Gold Nanoparticles Conjugated with Glycopeptides for Lectin Detection and Imaging on Cell Surface}, journal = {Protein & Peptide Letters}, year = 2018, } @article{CTT100773750, author = {I.V. Chang and H.Tsutsumi and H. Mihara}, title = {Screening for Concanavalin A Binders from a Mannose-modified α-Helix Peptide Phage Library}, journal = {Molecular BioSystems}, year = 2017, } @article{CTT100788725, author = {堤浩 and 澤田敏樹 and 三原久和}, title = {自己集合性ペプチドナノファイバーを用いたナノバイオ材料の創製}, journal = {Kobunshi Ronbunshu}, year = 2017, } @article{CTT100712221, author = {Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell Differentiation on Disk- and String-Shaped Hydrogels Fabricated from Ca(2+) Rresponsive Self-Assembling Peptides.}, journal = {Biopolymers}, year = 2016, } @article{CTT100809782, author = {Megumi Kawamura and Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell Proliferation and Differentiation on Functionalized Self-Assembling Peptide Hydrogels.}, journal = {Peptide science}, year = 2016, } @article{CTT100712222, author = {Hiroshi Tsutsumi and Kazuhiko Nakano and Hisakazu Mihara}, title = {Dihydrofolate Reductase Inhibitory Peptides Screened from a Structured Designed β-Loop Peptide Library Displayed on Phage}, journal = {Molecular BioSystems}, year = 2015, } @article{CTT100677099, author = {Ji Yang and Tadaomi Furuta and Minoru Sakurai and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {A Computational Study of the Interaction of Amphiphilic α-Helical Cell-Penetrating Peptides with Heparan Sulfate}, journal = {Bull. Chem. Soc. Jpn.}, year = 2014, } @article{CTT100673035, author = {Ji Yang and Hiroshi Tsutsumi and Tadaomi Furuta and Minoru Sakurai and Hisakazu Mihara}, title = {Interaction of Amphiphilic α-Helical Cell-Penetrating Peptides with Heparan Sulfate}, journal = {Org. Biomol. Chem.}, year = 2014, } @article{CTT100712224, author = {Hyejin Park and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell-Selective Intracellular Drug Delivery Using Doxorubicin and α-Helical Peptides Conjugated to Gold Nanoparticles}, journal = {Biomaterials}, year = 2014, } @article{CTT100712227, author = {Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Self-Assembling Peptide Nanofibers Promoting Cell Adhesion and Differentiation}, journal = {Biopolymers}, year = 2013, } @article{CTT100712230, author = {Chie Hashimoto and Wataru Nomura and Tetsuo Narumi and Fujino, Masayuki and Hiroshi Tsutsumi and Masaki Haseyama and Naoki Yamamoto and Tsutomu Murakami and Hirokazu Tamamura}, title = {Anti-HIV-1 Peptide Derivatives Based on the HIV-1 Co-receptor CXCR4}, journal = {ChemMedChem}, year = 2013, } @article{CTT100712231, author = {Kanako Arai and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {A Monosaccharide-Modified Peptide Phage Library for Screening of Ligands to Carbohydrate-Binding Proteins}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2013, } @article{CTT100712228, author = {Vu, Nhuan T. and Yoshitaka Moriwaki and Jose M. M. Caaveiro and Tohru Terada and Hiroshi Tsutsumi and Iraru Hamachi and Kentaro Shimizu and Kouhei Tsumoto}, title = {Selective Binding of Antimicrobial Porphyrins to the Heme-Receptor IsdH-HEAT3 of Staphylococcus aureus}, journal = {Protein Science}, year = 2013, } @article{CTT100712229, author = {Hyejin Park and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell Penetration and Cell-Selective Drug Delivery Using -Helix Peptides Conjugated with Gold Nanoparticles}, journal = {Biomaterials}, year = 2013, } @article{CTT100712232, author = {Hiroshi Tsutsumi and Hiroyuki Ohkusa and Hyejin Park and Tsuyoshi Takahashi and HIDEYA YUASA and Hisakazu Mihara}, title = {Gold Nanoparticles Conjugated with Monosaccharide-modified Peptide for Lectin Detection}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2012, } @article{CTT100643220, author = {T. Sawada and M. Tsuchiya and T. Takahashi and Hiroshi Tsutsumi and H. Mihara}, title = {Cell-Adhesive Hydrogels Composed of Peptide Nanofibers Responsive to Biological Ions}, journal = {Polymer Journal}, year = 2012, } @article{CTT100712234, author = {Yoshitaka Moriwaki and Jose M. M. Caaveiro and Tanaka, Yoshikazu and Hiroshi Tsutsumi and Iraru Hamachi and Kouhei Tsumoto}, title = {Molecular Basis of Recognition of Antibacterial Porphyrins by Heme-Transporter IsdH-NEAT3 of Staphylococcus aureus}, journal = {Biochemistry}, year = 2011, } @article{CTT100712235, author = {Hiroshi Tsutsumi and Seiichiro Abe and Tomoaki Mino and Wataru Nomura and Hirokazu Tamamura}, title = {Intense Blue Fluorescence in a Leucine Zipper Assembly}, journal = {ChemBioChem}, year = 2011, } @article{CTT100712238, author = {Wataru Nomura and Tomoaki Mino and Tetsuo Narumi and Nami Ohashi and Akemi Masuda and Chie Hashimoto and Hiroshi Tsutsumi and Hirokazu Tamamura}, title = {Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins}, journal = {Biopolymers}, year = 2010, } @article{CTT100712236, author = {Shintaro Suzuki and Maddali, Kasthuraiah and Chie Hashimoto and Urano, Emiko and Nami Ohashi and Tomohiro Tanaka and Ozaki, Taro and Arai, Hiroshi and Hiroshi Tsutsumi and Tetsuo Narumi and Wataru Nomura and Naoki Yamamoto and Pommier, Yves and Atsushi Komano and Hirokazu Tamamura}, title = {Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products: Structure-Activity Relationship Studies}, journal = {Bioorganic & Medicinal Chemistry}, year = 2010, } @article{CTT100712237, author = {Shintaro Suzuki and Urano, Emiko and Chie Hashimoto and Hiroshi Tsutsumi and Toru Nakahara and Tomohiro Tanaka and Yuta Nakanishi and Maddali, Kasthuraiah and Han, Yan and Hamatake, Makiko and Miyauchi, Kosuke and Pommie, Yves and Beutler, John A. and Sugiura, Wataru and Fuji, Hideyoshi and Hoshino, Tyuji and Kyoko Itotani and Wataru Nomura and Tetsuo Narumi and Naoki Yamamoto and Atsushi Komano and Hirokazu Tamamura}, title = {Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products}, journal = {Journal of Medicinal Chemistry}, year = 2010, } @article{CTT100712239, author = {Hiroshi Tsutsumi and Wataru Nomura and Seiichiro Abe and Tomoaki Mino and Akemi Masuda and Nami Ohashi and Tomohiro Tanaka and Kenji Ohba and Naoki Yamamoto and Kazunari Akiyoshi and Hirokazu Tamamura}, title = {Fluorogenically Active Leucine Zipper Peptides as Tag-Probe Pairs for Protein Imaging in Living Cells}, journal = {Angewandte Chemie-International Edition}, year = 2009, } @article{CTT100712241, author = {Tomohiro Tanaka and Hiroshi Tsutsumi and Wataru Nomura and Yasuaki Tanabe and Nami Ohashi and Esaka, Ai and Chihiro Ochiai and Sato, Jun and Kyoko Itotani and Tsutomu Murakami and Kenji Ohba and Naoki Yamamoto and Nobutaka Fujii and Hirokazu Tamamura}, title = {Structure-Activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold: Identification of the New Pharmacophore}, journal = {Organic & Biomolecular Chemistry}, year = 2008, } @article{CTT100712242, author = {Wataru Nomura and Yasuaki Tanabe and Hiroshi Tsutsumi and Tomohiro Tanaka and Kenji Ohba and Naoki Yamamoto and Hirokazu Tamamura}, title = {Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening}, journal = {Bioconjugate Chemistry}, year = 2008, } @article{CTT100712245, author = {Hirokazu Tamamura and Tomohiro Tanaka and Hiroshi Tsutsumi and Nemoto, Koji and Mizokami, Satoko and Nami Ohashi and Shinya Oishi and Nobutaka Fujii}, title = {Versatile Use of Acid-Catalyzed Ring-opening of β-Aziridinyl-α, β-Enoates to Stereoselective Synthesis of Peptidomimetics}, journal = {Tetrahedron}, year = 2007, } @article{CTT100712252, author = {Hirokazu Tamamura and Hiroshi Tsutsumi and Hiroyuki Masuno and Ogawa, T. and Kenichi Hiramatsu and Araki, T. and Ueda, S. and Shinya Oishi and Esaka, A. and Wang, Z. and Peiper, S. C. and Trent, J. O. and Nobutaka Fujii}, title = {Synthesis and Biological Evaluation of CXCR4 Antagonists as Pharmaceutical Agents}, journal = {Journal of Peptide Science}, year = 2006, } @article{CTT100712251, author = {Hirokazu Tamamura and Hiroshi Tsutsumi and Nobutaka Fujii}, title = {The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases}, journal = {Mini-Reviews in Medicinal Chemistry}, year = 2006, } @article{CTT100712255, author = {Hirokazu Tamamura and Akio Ojida and Ogawa, Teppei and Hiroshi Tsutsumi and Hiroyuki Masuno and Nakashima, Hideki and Naoki Yamamoto and Iraru Hamachi and Nobutaka Fujii}, title = {Identification of a New Class of Low Molecular Weight Antagonists against the Chemokine Receptor CXCR4 Having the Dipicolylamine-Zinc(II) Complex Structure}, journal = {Journal of Medicinal Chemistry}, year = 2006, } @article{CTT100712257, author = {Hirokazu Tamamura and Hiroshi Tsutsumi and Hiroyuki Masuno and Mizokami, Satoko and Kenichi Hiramatsu and Wang, Zixuan and Trent, John O. and Nakashima, Hideki and Naoki Yamamoto and Peiper, Stephen C. and Nobutaka Fujii}, title = {Development of Linear Type of Low Molecular Weight CXCR4 Antagonists Based on T140 Analogs}, journal = {Organic & Biomolecular Chemistry}, year = 2006, } @article{CTT100712254, author = {Yousuke Takaoka and Hiroshi Tsutsumi and Noriyuki Kasagi and Eiji Nakata and Iraru Hamachi}, title = {One-Pot and Sequential Organic Chemistry on an Enzyme Surface to Tether a Fluorescent Probe at the Proximity of the Active Site with Restoring Enzyme Activity}, journal = {Journal of the American Chemical Society}, year = 2006, } @article{CTT100712256, author = {Akio Ojida and Masa-aki Inoue and Mito-oka, Y and Hiroshi Tsutsumi and Sada, K and Iraru Hamachi}, title = {Effective Disruption of Phosphoprotein-Protein Surface Interaction Using Zn(II) Dipicolylamine-Based Artificial Receptors via Two-Point Interaction}, journal = {Journal of the American Chemical Society}, year = 2006, } @article{CTT100712259, author = {Hirokazu Tamamura and Esaka, A and Ogawa, T and Araki, T and Ueda, S and Wang, ZX and Trent, JO and Hiroshi Tsutsumi and Hiroyuki Masuno and Nakashima, H and Naoki Yamamoto and Peiper, SC and Akira Otaka and Nobutaka Fujii}, title = {Structure-Activity Relationship Studies on CXCR4 Antagonists Having Cyclic Pentapeptide Scaffolds}, journal = {Organic & Biomolecular Chemistry}, year = 2005, } @article{CTT100712258, author = {Akio Ojida and Hiroshi Tsutsumi and Noriyuki Kasagi and Iraru Hamachi}, title = {Suzuki Coupling for Protein Modification}, journal = {Tetrahedron Letters}, year = 2005, } @article{CTT100712260, author = {Hiroshi Tsutsumi and Hiroshi Ikeda and Hisakazu Mihara and Akihiko Ueno}, title = {Enantioselective Ester Hydrolysis Catalyzed by β-Cyclodextrin Conjugated with β-Hairpin Peptides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2004, } @article{CTT100712261, author = {Hiroshi Tsutsumi and Keita Hamasaki and Hisakazu Mihara and Akihiko Ueno}, title = {Rate Enhancement and Enantioselectivity in Ester Hydrolysis Catalysed by Cyclodextrin-Peptide Hybrids}, journal = {Journal of the Chemical Society Perkin Transactions 2}, year = 2000, } @article{CTT100712262, author = {Hiroshi Tsutsumi and Keita Hamasaki and Hisakazu Mihara and Akihiko Ueno}, title = {Cyclodextrin-Peptide Hybrid as a Hydrolytic Catalyst Having Multiple Functional Groups}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2000, } @misc{CTT100785177, author = {Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Self-Assembly of Designed Peptides and Their Nanomaterials Applications}, year = 2013, } @misc{CTT100712226, author = {Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Soft Materials Based on Designed Self-Assembling Peptides: from Design to Application}, year = 2013, } @misc{CTT100712244, author = {Hirokazu Tamamura and Hiroshi Tsutsumi and Wataru Nomura and Tomohiro Tanaka and Nobutaka Fujii}, title = {A Future Perspective on the Development of Chemokine Receptor CXCR4 Antagonists}, year = 2008, } @misc{CTT100712243, author = {Hirokazu Tamamura and Hiroshi Tsutsumi and Wataru Nomura and Nobutaka Fujii}, title = {Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing}, year = 2008, } @misc{CTT100712246, author = {Hiroshi Tsutsumi and Tomohiro Tanaka and Nami Ohashi and Hiroyuki Masuno and Hirokazu Tamamura and Kenichi Hiramatsu and Araki, Takanobu and Ueda, Satoshi and Shinya Oishi and Nobutaka Fujii}, title = {Therapeutic Potential of the Chemokine Receptor CXCR4 Antagonists as Multifunctional Agents}, year = 2007, } @misc{CTT100712248, author = {Hiroshi Tsutsumi and Hirokazu Tamamura and Nobutaka Fujii}, title = {Inhibitors of the Chemokine Receptor CXCR4. Chemotherapy of AIDS, Metastatic Cancer, Leukemia and Rheumatoid Arthritis}, year = 2007, } @misc{CTT100712249, author = {Hirokazu Tamamura and Hiroshi Tsutsumi and Hiroyuki Masuno and Nobutaka Fujii}, title = {Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetra- and Pentapeptide-Scaffolds towards the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis}, year = 2007, } @misc{CTT100712253, author = {Hirokazu Tamamura and Hiroshi Tsutsumi}, title = {Specific Probes for Chemokine Receptors}, year = 2006, }