@article{CTT100718549, author = {Guangzhe Li and Soyoko Azuma and Hidemitsu Minegishi and Hiroyuki Nakamura}, title = {Synthesis and biological evaluation of meta-carborane-containing phenoxyacetanilides as inhibitors of hypoxia-inducible factor (HIF)-1 transcriptional activity}, journal = {Journal of Organometallic Chemistry}, year = 2015, } @article{CTT100705286, author = {Hiroyuki Nakamura and Shoji Tachikawa and Shinichi Sato and Hisanao Hazama and Kunio Awazu}, title = {Localization-dependent cell-killing effects of protoporphyrin (PPIX)-lipid micelles and liposomes in photodynamic therapy}, journal = {Bioorganic & Medicinal Chemistry}, year = 2015, } @article{CTT100718553, author = {Shinichi Sato and Kosuke Nakamura and Hiroyuki Nakamura}, title = {Tyrosine-Specific Chemical Modification with in situ Hemin-Activated Luminol Derivatives}, journal = {ACS chemical biology}, year = 2015, } @article{CTT100705297, author = {Hiroyuki Nakamura and T Sato and Akira Sato and Tasuku Ito and Syoji Imamichi and Sota Kikuhara and Hiroaki Fujimori and Takahisa Hirai and Soichiro Saito}, title = {Proteomic analysis of cellular response induced by boron neutron capture reaction in human squamous cell carcinoma SAS cells}, journal = {Applied Radiation and Isotopes}, year = 2015, } @article{CTT100718550, author = {Guangzhe Li and Soyoko Azuma and Shinichi Sato and Hidemitsu Minegishi and Hiroyuki Nakamura}, title = {ortho-Carboranylphenoxyacetanilides as inhibitors of hypoxia-inducible factor (HIF)-1 transcriptional activity and heat shock protein (HSP) 60 chaperon activity}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2015, } @article{CTT100718554, author = {Hiroyuki Nakamura and Hayato Koganei and Shoji Tachikawa and E. El-Zaria Mohamed}, title = {Synthesis of Oligo-closo-dodecaborates by Hüisgen Click Reaction as Encapsulated Agents for Preparation of High-Boron-Content Liposomes for Neutron Capture Therapy}, journal = {New J. Chem}, year = 2015, } @article{CTT100705294, author = {Hiroyuki Nakamura}, title = {C(sp3)–H versus C(sp3)–C(sp) in Activation of Propargylic Amines under Transition-Metal Catalysis}, journal = {Synlett}, year = 2015, } @article{CTT100718543, author = {Hidemitsu Minegishi and Yushi Futamura§ and Shinji Fukashiro and Makoto Muroi and Makoto Kawatani and Hiroyuki Osada and Hiroyuki Nakamura}, title = {Methyl 3-((6-Methoxy-1, 4-dihydroindeno [1, 2-c] pyrazol-3-yl) amino) benzoate (GN39482) as a Tubulin Polymerization Inhibitor Identified by MorphoBase and ChemProteoBase Profiling Methods}, journal = {Journal of medicinal chemistry}, year = 2015, } @article{CTT100718541, author = {Mizuho Inai and Masaya Yamauchi and Norihiro Honda and Hisanao Hazama and Shoji Tachikawa and Hiroyuki Nakamura and Tomoki Nishida and Hidehiro Yasuda and Yasufumi Kaneda and Kunio Awazu}, title = {Hemagglutinating virus of Japan envelope (HVJ-E) allows targeted and efficient delivery of photosensitizer for photodynamic therapy against advanced prostate cancer}, journal = {Optical Molecular Probes, Imaging and Drug Delivery}, year = 2015, } @article{CTT100718556, author = {Hyun Seung Ban and Hiroyuki Nakamura}, title = {Boron-Based Drug Design}, journal = {The Chemical Record}, year = 2015, } @article{CTT100705299, author = {Hiroyuki Nakamura and Kunio Awazu and Mizuho Inai}, title = {Photodynamic therapy using hemagglutinating virus of Japan envelope (HVJ-E): a novel therapeutic approach for the treatment of hormone antagonistic prostate cancer}, journal = {Proc. SPIE 9308 Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIV}, year = 2015, } @article{CTT100718559, author = {Hiroyuki Nakamura and Lisa Tazaki and Daisuke Kanoh and Shinichi Sato}, title = {Diaryl-substituted carboranes as inhibitors of hypoxia inducible factor-1 transcriptional activity}, journal = {Pure and Applied Chemistry}, year = 2015, } @article{CTT100705289, author = {中村浩之}, title = {ホウ素化合物・薬剤の歴史と現状}, journal = {RADIOISOTOPES}, year = 2015, } @article{CTT100705291, author = {中村浩之 and 山内 将哉 and 本多 典広 and 立川 将士 and 粟津 邦男}, title = {抗腫瘍効果を持つ非ウイルスベクター用いた薬剤耐性前立腺がん細胞に対する高効率な光線力学療法}, journal = {日本レーザー医学会誌}, year = 2015, } @inproceedings{CTT100823259, author = {S. Sato and K. Nakamura and H. Nakamura}, title = {Tyrosine-selective chemical modification using single-electron-transfer catalyst}, booktitle = {}, year = 2015, } @inproceedings{CTT100823258, author = {Hiroyuki Nakamura}, title = {Overview and Prospect of Boron Agents for Neutron Capture Therapy}, booktitle = {}, year = 2015, } @inproceedings{CTT100705336, author = {Hiroyuki Nakamura}, title = {Discovery of Carboranylphenoxy-acetanilides as Inhibitors of heat shock protein (HSP) 60 chaperon activity}, booktitle = {}, year = 2015, } @inproceedings{CTT100838248, author = {佐々木悠介 and 上原至雅 and Hiroyuki Nakamura}, title = {Synthesis of Benzamidines as a Specific Inhibitor Targeting to EpidermalGrowthFactor Receptor and Vascular Endothelial Growth Factor Receptor Tyrosine Kinases}, booktitle = {}, year = 2015, } @inproceedings{CTT100823261, author = {S. Kikuchi and D. Kanoh and S. Sato and H. Nakamura}, title = {Use of serum albumin as an efficient boron delivery carrier for neutron capture therapy}, booktitle = {}, year = 2015, } @inproceedings{CTT100700055, author = {Shinichiro Fuse and Yuto Mifune and Nobutake Tanabe and Hiroyuki Nakamura and Takashi Takahashi}, title = {Utilization of microflow technology for the site-selective modification of multifunctionalized molecules}, booktitle = {}, year = 2015, } @inproceedings{CTT100700106, author = {Taiki Morita and Shinichiro Fuse and Keisuke Matsumura and Hirotaka Sugiyama and Daisuke Kobayashi and Hiroshi Tanaka and Hiroyuki Nakamura and Takashi Takahashi}, title = {Rapid synthesis of tri/tetraaryl-substituted pyrazoles via [3+2] cycloadditon and C-H direct arylation approaches}, booktitle = {}, year = 2015, } @inproceedings{CTT100823260, author = {Hiroyuki Nakamura}, title = {Development of boronated liposomes as efficient boron delivery vehicles for neutron capture therapy,}, booktitle = {}, year = 2015, } @inproceedings{CTT100705335, author = {Hiroyuki Nakamura}, title = {Target Protein-Selective Labeling and Inactivation Using Ligand-Directed Ru(bpy)3 Photocatalysts}, booktitle = {}, year = 2015, } @inproceedings{CTT100698800, author = {盛田大輝 and 田中浩士 and 中村浩之 and 布施新一郎}, title = {4連続の直接アリール化による4置換ピラゾールの合成とその発光特性}, booktitle = {}, year = 2015, } @inproceedings{CTT100699088, author = {布施新一郎 and 小竹佑磨 and 御舩悠人 and 中村浩之 and 田中浩士}, title = {マイクロフローリアクター内での四連続反応によるαアリールカルボニル化合物合成法の開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100823256, author = {S. Sato and K. Nakamura and H. Nakamura}, title = {Heme-Catalyzed Tyrosine Click Reaction with Luminol Derivatives}, booktitle = {}, year = 2015, } @inproceedings{CTT100823257, author = {Hiroyuki Nakamura}, title = {Anticancer Drug Design Using the Element Boron}, booktitle = {}, year = 2015, } @inproceedings{CTT100705337, author = {Hiroyuki Nakamura}, title = {Highly Boronated Liposomes as Efficient Boron Delivery Vehicles for Neutron Capture Therapy}, booktitle = {}, year = 2015, } @inproceedings{CTT100823253, author = {菊地 俊介 and 佐藤 伸一 and 中村 浩之}, title = {血清アルブミンを用いた新しいホウ素送達法の開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100696265, author = {盛田大輝 and 田中浩士 and 中村浩之 and 布施新一郎}, title = {連続的C-H結合直接アリール化による4置換ピラゾールの合成}, booktitle = {}, year = 2015, } @inproceedings{CTT100696657, author = {御舩悠人 and 布施新一郎 and 田中浩士 and 中村浩之 and 高橋孝志}, title = {カルボン酸の迅速かつ強力な活性化を基盤とするマイクロフローペプチド合成法の開発とフェグリマイシンの合成研究}, booktitle = {}, year = 2015, } @inproceedings{CTT100823254, author = {中村浩之}, title = {ホウ素をつかってがんに挑む 〜ホウ素創薬の最前線〜}, booktitle = {}, year = 2015, } @inproceedings{CTT100705345, author = {中村浩之}, title = {何故新しいホウ素薬剤は開発されないのか?—これからのBoron Delivery Systemを考えるー}, booktitle = {}, year = 2015, } @inproceedings{CTT100823251, author = {中村浩之 and 立川将士 and Clara Vinas and 鈴木実 and 小野公二}, title = {ホウ素高集積化リポソームを指向した内封ホウ素薬剤開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100823252, author = {立川将士 and 佐藤伸一 and 間久直 and 金田安史 and 粟津邦男 and 中村浩之}, title = {ポルフィリン脂質リポソームの細胞内局在とPDT効果}, booktitle = {}, year = 2015, } @inproceedings{CTT100705344, author = {中村浩之}, title = {光を使って生命機能を探る・操る}, booktitle = {}, year = 2015, } @inproceedings{CTT100823246, author = {中村浩之 and 峯岸秀光 and 室井誠 and 二村友史 and 川谷誠 and 長田裕之}, title = {高い細胞増殖阻害を有するインデノピラゾールの発見とプロファイリング法による阻害機構の解明}, booktitle = {}, year = 2015, } @inproceedings{CTT100823247, author = {佐藤伸一 and 中村公亮 and 中村浩之}, title = {ルミノール誘導体を用いたチロシン残基に選択的な共有結合形成反応の開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100823248, author = {李 廣哲 and 峯岸 秀充 and 佐藤 伸一 and 中村 浩之}, title = {カルボラン骨格を有する新規Hsp60阻害剤の開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100823249, author = {青野晴美 and 川谷誠 and 二村友史 and 室井誠 and 峯岸秀充 and 中村浩之 and 長田裕之}, title = {MorphoBaseおよびChemProteoBaseを用いたGN39482の標的同定}, booktitle = {}, year = 2015, } @inproceedings{CTT100823250, author = {中村浩之}, title = {インデノピラゾール骨格を基軸とした創薬研究}, booktitle = {}, year = 2015, } @inproceedings{CTT100823129, author = {Hiroyuki Nakamura}, title = {Development of Liposomes for Efficient Boron Neutron Capture Therapy,}, booktitle = {}, year = 2015, } @inproceedings{CTT100823130, author = {Hiroyuki Nakamura}, title = {Development of Liposomes for Efficient Boron Neutron Capture Therapy,}, booktitle = {}, year = 2015, } @inproceedings{CTT100823127, author = {中村公亮 and 佐藤伸一 and 中村浩之}, title = {Luminol誘導体を用いた鉄触媒存在下でのTyr残基高選択的ラベル化反応}, booktitle = {}, year = 2015, } @inproceedings{CTT100823128, author = {Hiroyuki Nakamura}, title = {Development of Liposomes for Efficient Boron Neutron Capture Therapy,}, booktitle = {}, year = 2015, } @inproceedings{CTT100823126, author = {中村浩之 and 峯岸秀充 and 室井誠 and 二村友史 and 川谷誠 and 長田裕之}, title = {高い細胞増殖阻害を有するインデノピラゾール化合物の発見とその作用機序解明}, booktitle = {}, year = 2015, } @inproceedings{CTT100823606, author = {峯岸秀充 and 中村浩之}, title = {ベンゾフロピラゾール化合物の合成とHIF-1転写活性への影響}, booktitle = {}, year = 2015, } @inproceedings{CTT100685024, author = {H. Nakamura and Shinichi Sato}, title = {Development of Ligand-directed Ru(bpy)3 Photocatalysts for Target Protein Knockdown and Labeling}, booktitle = {}, year = 2015, } @inproceedings{CTT100718544, author = {Mizuho Inai and Masaya Yamauchi and Norihiro Honda and Hisanao Hazama and Shoji Tachikawa and Hiroyuki Nakamura and Tomoki Nishida and Hidehiro Yasuda and Yasufumi Kaneda and Kunio Awazu}, title = {Photodynamic therapy using hemagglutinating virus of Japan envelope (HVJ-E): a novel therapeutic approach for the treatment of hormone antagonistic prostate cancer}, booktitle = {SPIE BiOS}, year = 2015, } @inproceedings{CTT100823600, author = {Hiroyuki Nakamura}, title = {Development of Chemical Tools for Target Protein-Selective Identification and Selective Modification}, booktitle = {}, year = 2015, } @inproceedings{CTT100823601, author = {佐藤伸一 and 森田耕平 and 中村浩之}, title = {リガンド連結型Ru光触媒を用いたタンパク質ノックダウンとラベル化の制御}, booktitle = {}, year = 2015, } @inproceedings{CTT100823602, author = {Hiroyuki Nakamura}, title = {Development of Liposomes for Efficient Boron Neutron Capture Therapy}, booktitle = {}, year = 2015, } @inproceedings{CTT100823603, author = {中村公亮 and 佐藤伸一 and 中村浩之}, title = {ルミノール誘導体を用いた鉄触媒存在下でのTyr残基特異的タンパク質ラベル化反応}, booktitle = {}, year = 2015, } @inproceedings{CTT100823604, author = {菊地俊介 and 加納大輔 and 佐藤伸一 and 中村浩之}, title = {中性子捕捉療法のための血清アルブミンを用いた新しいホウ素送達法の開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100823605, author = {大内俊明 and 峯岸秀充 and 中村浩之}, title = {イミダゾピリジン骨格を有する新規HIF-1α阻害剤の開発}, booktitle = {}, year = 2015, } @inproceedings{CTT100823599, author = {Hiroyuki Nakamura}, title = {Development of Chemical Tools for Target Protein-Selective Identification and Modification}, booktitle = {}, year = 2015, } @inproceedings{CTT100685025, author = {中村浩之}, title = {DDSによるがん治療の最前線}, booktitle = {}, year = 2015, } @inproceedings{CTT100823598, author = {M. Inai and M. Yamauchi and N. Honda and H. Hazama and S. Tachikawa and H. Nakamura and Y. Kaneda and K. Awazu}, title = {Therapeutic effect of porphyrus envelope-mediated photodynamic therapy: a novel therapeutic approach for the treatment of hormone antagonistic prostate cancer}, booktitle = {}, year = 2015, } @inproceedings{CTT100720055, author = {中村浩之}, title = {ホウ素でがんに挑む}, booktitle = {}, year = 2015, } @inproceedings{CTT100823597, author = {中村 浩之}, title = {がん細胞内部で放射線を発生させる次世代治療法〜ホウ素中性子捕捉療法}, booktitle = {}, year = 2015, } @misc{CTT100736999, author = {中村浩之 and 峯岸 秀充}, title = {ベンゾフロピラゾール誘導体}, howpublished = {公開特許}, year = 2016, month = {}, note = {特願2015-092606(2015/04/30), 特開2016-210687(2016/12/15)} }