@article{CTT100745068,
  author = {T. Kuchimaru and T. Suka and K. Hirota and T. Kadonosono and S. Kizaka-Kondoh},
  title = {A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system},
  journal = {Sci Rep},
  year = 2016,
}

@article{CTT100745075,
  author = {近藤 科江 and 口丸 高弘 and 門之園 哲哉},
  title = {生体光イメージング研究「生体の窓」活用の最前線},
  journal = {実験医学},
  year = 2016,
}

@article{CTT100712113,
  author = {Hoang NT and Kadonosono T and Kuchimaru T and Kizaka-Kondoh S.},
  title = {Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model.},
  journal = {Cancer Science},
  year = 2016,
}

@article{CTT100712114,
  author = {Kuchimaru T. and Iwano S. and Kiyama M. and Mitsumata S. and Kadonosono T. and Niwa H. and Maki S. and Kizaka-Kondoh S.},
  title = {A luciferin analog generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging.},
  journal = {Nat Commun,},
  year = 2016,
}

@article{CTT100709403,
  author = {Sachiko Horie and Yasuhiro Suzuki and Miho Kobayashi and Tetsuya Kadonosono and Shinae Kizaka-Kondoh and Tetsuya Kodama and Yasufumi Sato},
  title = {Distinctive role of vasohibin-1A and its splicing variant vasohibin-1B in tumor angiogenesis},
  journal = {Cancer Gene Therapy},
  year = 2016,
}

@article{CTT100712738,
  author = {近藤科江 and 口丸高弘 and 門之園哲哉},
  title = {がん間質における低酸素応答が悪性化を駆動する},
  journal = {実験医学},
  year = 2016,
}

@inproceedings{CTT100745244,
  author = {酒井 栞 and 門之園 哲哉 and 遠藤 みのり and 口丸 高弘 and 井上 正宏 and 近藤 科江},
  title = {肺がん細胞株による休眠がん細胞標的薬剤の有効性評価},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745243,
  author = {伊藤 雄大 and 門之園 哲哉 and ThiHongNgoc Hoang and 口丸 高弘 and 近藤 科江},
  title = {HIF活性化細胞を標的とした新規融合タンパク質製剤の物性評価},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745242,
  author = {PONGSUCHART M and 米澤 早紀子 and Hoang ThiHongNgoc and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {Identification of genes regulating osteosarcoma extravasation in lung metastasis},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745241,
  author = {礒崎 達大 and 片岡 直也 and 峯岸 美紗 and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {早期骨転移形成過程におけるがん細胞と骨髄微笑環境の相互作用解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745097,
  author = {門之園 哲哉 and Wanaporn Yimchuen and 塩澤 唯 and 北澤 舞花 and 太田 優美 and 口丸 高弘 and 近藤 科江},
  title = {「構造ゆらぎ」制御による高性能な抗体医薬品代替分子の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745240,
  author = {塩澤 唯 and 門之園 哲哉 and 北澤 舞花 and Yimchuen Wanaporn and 口丸 高弘 and 瀧 真清 and 伊東 祐二 and 近藤 科江},
  title = {標的結合ペプチドの構造ゆらぎ抑制による高親和性PD-1結合タンパク質の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745239,
  author = {北澤 舞花 and 門之園 哲哉 and 塩澤 唯 and Yimchuen Wanaporn and 口丸 高弘 and 近藤 科江},
  title = {構造ゆらぎを抑制した高親和性HER2標的結合分子スクリーニング技術の開発},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745238,
  author = {礒崎 達大 and 片岡 直也 and 峯岸 美紗 and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {定量的生物発光イメージングによる早期骨転移微小環境の解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745237,
  author = {塩澤 唯 and 門之園 哲哉 and 北澤 舞花 and Wanaporn Yimchuen and 口丸 高弘 and 瀧 真澄 and 伊東 祐二 and 近藤 科江},
  title = {標的結合ペプチドの構造ゆらぎ抑制による高親和性抗PD-1タンパク質の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745236,
  author = {北澤 舞花 and 門之園 哲哉 and 塩澤 唯 and 口丸 高弘 and 近藤 科江},
  title = {構造ゆらぎの制御によるHER2高親和性抗体代替分子の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745235,
  author = {礒崎 達大 and 片岡 直也 and 峯岸 美紗 and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {マルチ生物発光レポーターシステムを用いた骨転移病巣形成の分子機構の解明},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745203,
  author = {口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {近赤外生物発光を用いたがん組織の非侵襲イメージング},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745202,
  author = {Shinae Kondoh and Takahiro Kuchimaru and Tetsuya Kadonosono},
  title = {Symposium 5: The roles of vascular remodeling in tissue hypoxia Imaging strategies for detection of HIF activity},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745199,
  author = {門之園 哲哉 and Wanaporn Yimchuen and 塩澤 唯 and 北澤 舞花 and 太田 優美 and 口丸 高弘 and 近藤 科江},
  title = {腫瘍悪性化促進因子活性を中和する分子標的薬創製に向けた抗体代替分子設計},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745194,
  author = {椿 卓也 and 門之園 哲哉 and 塩澤 唯 and 口丸 高弘 and 近藤 科江},
  title = {新規接着性ミエロイド細胞による腫瘍悪性化機構の機能解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745195,
  author = {酒井 栞 and 門之園 哲哉 and 遠藤 みのり and 口丸 高弘 and 井上 正宏 and 近藤 科江},
  title = {肺がん細胞株による休眠がん細胞標的薬剤の有効性評価},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745196,
  author = {片岡 直也 and 口丸 高弘 and 礒崎 達大 and 峯岸 美紗 and 門之園 哲哉 and 近藤 科江},
  title = {転移早期過程における前立腺がんと骨髄間質細胞の相互作用解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745197,
  author = {口丸 高弘 and 岩野 智 and 三股 舜 and 牧 昌次郎 and 門之園 哲哉 and 近藤 科江},
  title = {近赤外生物発光イメージングによる生体深部組織の可視化},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745198,
  author = {米澤 早紀子 and Mongkol Pongschart and Diem Tran and 口丸 高弘 and Ngoc Honag and 門之園 哲哉 and 近藤 科江},
  title = {骨肉腫細胞の肺転移における血管外浸潤過程を制御する分子機構の解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745228,
  author = {Takahiro Kuchimaru and Tetsuya Kadonosono and Shinae Kizaka-Kondoh},
  title = {Bioluminescence imaging in living animals},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100741259,
  author = {YIMCHUEN WANAPORN and 門之園 哲哉 and 古田 忠臣 and 塩澤 唯 and 北澤 舞花 and 口丸 高弘 and 櫻井 実 and 近藤 科江},
  title = {Development of IgG-based antibody mimetics with a constrained target-binding peptide},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100784501,
  author = {近藤科江 and 口丸高弘 and 門之園哲哉},
  title = {In vivo imaging of HIF activity},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745246,
  author = {濱道 修生 and 梅田 泉 and 門之園 哲哉 and 近藤 科江 and 藤井 博史},
  title = {腫瘍内Hypoxia Inducible Factor 1α (HIF1α) 発現領域をターゲットしたTOP3の体内動態の検討},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745245,
  author = {口丸 高弘 and 岩野 智 and 木山 正宏 and 三股 舜 and 門之園 哲哉 and 丹羽 治樹 and 牧 昌次郎 and 近藤 科江},
  title = {近赤外発光基質による生体深部組織の高感度イメージング},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745096,
  author = {口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {生物発光を用いた腫瘍組織の低酸素イメージング},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745200,
  author = {Shinae Kondoh and Tetsuya Kadonosono and Takahiro Kuchimaru},
  title = {In vivo imaging of HIF activity},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745257,
  author = {伊藤 雄大 and 門之園 哲哉 and ThiHongNgoc Hoang and 口丸 高弘 and 近藤 科江},
  title = {低酸素がんを標的とした融合タンパク質製剤の物性評価},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100741254,
  author = {YIMCHUEN WANAPORN and 門之園 哲哉 and 古田 忠臣 and 塩澤 唯 and 北澤 舞花 and 口丸 高弘 and 櫻井 実 and 近藤 科江},
  title = {Evaluation of immunoglobulin-based antibody mimetics with a constrained target-binding peptide},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745190,
  author = {口丸 高弘 and 岩野 智 and 三股 舜 and 牧 昌次郎 and 門之園 哲哉 and 近藤 科江},
  title = {近赤外生物発光イメージングによる深部組織がんの高感度検出},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745191,
  author = {梅田 泉 and 柿島 祐 and 石川 龍太郎 and 濱道 修生 and 口丸 高弘 and 門之園 哲哉 and 近藤 科江 and 藤井 博史},
  title = {腫瘍内低酸素誘導転写因子活性の核医学画像診断の試み},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745192,
  author = {門之園 哲哉 and Wanaporn Yimchuen and 塩澤 唯 and 北澤 舞花 and 太田 優美 and 口丸 高弘 and 近藤 科江},
  title = {標的結合ペプチドのゆらぎ制御による抗体代替分子の創製法},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745193,
  author = {門之園 哲哉 and YIMCHUEN WANAPORN and 塩澤 唯 and 北澤 舞花 and 太田 優美 and 口丸 高弘 and 近藤 科江},
  title = {A protein-engineering method for identifying a scaffold making peptides structurally constrained in order to develop high-affinity antibody mimetics},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745247,
  author = {塩澤 唯 and 門之園 哲哉 and 北澤 舞花 and YIMCHUEN WANAPORN and 口丸 高弘 and Masumi Taki and Yuji Ito and 近藤 科江},
  title = {Development of a high-affinity anti-PD-1 small protein harboring a constrained PD-1-binding peptide},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745248,
  author = {北澤 舞花 and 門之園 哲哉 and 塩澤 唯 and YIMCHUEN WANAPORN and 口丸 高弘 and Masumi Taki and Yuji Ito and 近藤 科江},
  title = {Development of fibronectin-based small protein harboring a structurally constrained HER2-binding peptide},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745249,
  author = {椿 卓也 and 門之園 哲哉 and 塩澤 唯 and 口丸 高弘 and 近藤 科江},
  title = {腫瘍内新規接着性ミエロイド細胞の機能解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745250,
  author = {YIMCHUEN WANAPORN and 門之園 哲哉 and 塩澤 唯 and 北澤 舞花 and 口丸 高弘 and 近藤 科江},
  title = {Development of antibody mimetics with constrained target-binding peptide for cancer therapy},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745251,
  author = {塩澤 唯 and 門之園 哲哉 and 北澤 舞花 and Wanaporn Yimchuen and 口丸 高弘 and 近藤 科江},
  title = {ゆらぎ抑制標的結合ペプチドによるPD-1結合低分子量タンパク質の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745252,
  author = {酒井 栞 and 門之園 哲哉 and 遠藤 みのり and 口丸 高弘 and 井上 正宏 and 近藤 科江},
  title = {肺がん細胞株による休眠がん細胞標的薬剤の薬効評価},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745253,
  author = {礒崎 達大 and 口丸 高弘 and 片岡 直也 and 門之園 哲哉 and 近藤 科江},
  title = {早期骨転移形成過程における腫瘍微小環境およびがん細胞と骨髄間質細胞の相互作用解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745255,
  author = {TRAN T.PHUONG DIEM and PONGSUCHART M and 米澤 早紀子 and Hoang ThiHongNgoc and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {Analysis of Wnt signaling involvement in lung metastasis by using murine osteosarcoma cell lines},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745256,
  author = {米澤 早紀子 and Mongkol Pongsuchart and Diem Tran and Hoang Thi Hong Ngoc and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {骨肉腫の肺転移における血管外浸潤過程を制御する分子機構の解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745227,
  author = {Tetsuya Kadonosono and Tadashi Shiozawa and Takuya Tsubaki and Takahiro Kuchimaru and Shinae Kizaka-Kondoh},
  title = {In vivo optical imaging of protumoral functions of adherent myeloid cells},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745087,
  author = {門之園哲哉},
  title = {化学合成可能な高性能抗体代替分子の開発技術},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745189,
  author = {椿 卓也 and 門之園 哲哉 and 塩澤 唯 and 口丸 高弘 and 近藤 科江},
  title = {腫瘍内新規接着性ミエロイド細胞による腫瘍悪性化機構の解明},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745226,
  author = {Takahiro Kuchimaru and Kenji Nakagawa and Tatsuhiro Isozaki and Tetsuya Kadonosono and Shinae Kizaka-Kondoh},
  title = {A multi-bioluminescence reporter system visualized molecular basis of bone metastasis},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745188,
  author = {門之園哲哉},
  title = {ペプチドの「構造ゆらぎ」抑制による高性能な標的結合分子創製技術},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745259,
  author = {北澤 舞花 and 門之園 哲哉 and 塩澤 唯 and 口丸 高弘 and 近藤 科江},
  title = {構造ゆらぎ抑制によるHER2高親和性抗体代替分子の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745258,
  author = {塩澤 唯 and 門之園 哲哉 and 北澤 舞花 and 口丸 高弘 and 近藤 科江},
  title = {構造ゆらぎ抑制による高親和性PD-1結合タンパク質の創製},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745186,
  author = {酒井 栞 and 門之園 哲哉 and 口丸 高弘 and 井上 正宏 and 近藤 科江},
  title = {休眠がん細胞を標的とする薬剤の特異性評価と標的分子の探索},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745187,
  author = {椿 卓也 and 門之園 哲哉 and 口丸 高弘 and 近藤 科江},
  title = {新規接着性ミエロイド細胞による腫瘍悪性化機構の解明},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100709231,
  author = {神永真帆 and 石田忠 and 門之園哲哉 and 近藤科江 and 小俣透},
  title = {がん細胞特異的結合ペプチドスクリーニングのためのマイクロ流体デバイス},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745225,
  author = {Tatsuhiro Isozaki and Takahiro Kuchimaru and Naoya Kataoka and Kenji Nakagawa and Tetsuya Kadonosono and Shinae Kizaka-Kondoh},
  title = {A multi-bioluminescence reporter system to decipher ineractions between cancer cells and bone marrow stromal cells in early bone metastasis},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745183,
  author = {PONGSUCHART M and Nguyen KhaThe and 米澤 早紀子 and Hoang ThiHongNgoc and 口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {Identification of responsible genes for osteosarcoma extravasation in lung metastasis by using in vivo image-guided system},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745224,
  author = {Takahiro Kuchimaru and Sataoshi Iwano and Masahiro Kiyama and Shun Mitsumata and Tetsuya Kadonosono and Haruki Niwa and Shojiro Maki and Shinae Kizaka-Kondoh},
  title = {A luciferin analog generating near-infrared bioluminescence improves detection sensitivity of deep-tissue tumor},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100712748,
  author = {近藤 科江 and 門之園 哲哉 and Hoang Thi Hong Ngoc and 伊藤雄大 and 口丸高弘},
  title = {低酸素誘導転写因子HIFが活性化したがんを標的にした融合タンパク質製剤を用いた},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100712747,
  author = {Shinae Kondoh and Tetsuya Kadonosono and Takahiro Kuchimaru},
  title = {Imaging of HIF-active tumors: Exploration tool for malignancy},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745260,
  author = {門之園 哲哉 and Wanaporn Yimchuen and 塩澤 唯 and 北澤 舞花 and 口丸 高弘 and 近藤 科江},
  title = {標的結合ペプチドの「構造ゆらぎ」抑制による高性能な腫瘍イメージングプローブの開発},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745261,
  author = {口丸 高弘 and 岩野 智 and 木山 正啓 and 三股 舜 and 門之園 哲哉 and 丹羽 治樹 and 牧 昌次郎 and 近藤 科江},
  title = {深部組織の高感度イメージングを可能にする近赤外ルシフェリンアナログ},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745262,
  author = {片岡 直也 and 口丸 高弘 and 中川 賢治 and 礒崎 達大 and 門之園 哲哉 and 近藤 科江},
  title = {発光イメージングを用いた骨転移早期過程における前立腺がんと骨髄間質細胞の相互作用解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745185,
  author = {門之園 哲哉 and 口丸 高弘 and 近藤 科江},
  title = {抗体由来標的結合ペプチドの「構造ゆらぎ」抑制による高性能な抗体代替分子の開発},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745184,
  author = {近藤 科江 and 門之園 哲哉 and Hoang Thi Hong Ngoc and 伊藤雄大 and 口丸高弘},
  title = {HIFが活性化したがんを標的にした融合タンパク質製剤を用いた難治がん治療法の開発},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745182,
  author = {近藤 科江 and 門之園 哲哉 and 口丸 高弘},
  title = {Imaging of HIF-active tumors: Exploration tool for malignancy},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745181,
  author = {門之園哲哉},
  title = {化学合成可能な高性能抗体代替ペプチドの作製技術},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745222,
  author = {Shinae Kizaka-Kondoh and Takahiro Kuchimaru and Tomoya Suka and Tetsuya Kadonosono},
  title = {A novel injectable bioluminescence resonance energy transfer-based in vivo imaging probe for HIF-active cancer cells},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745179,
  author = {口丸 高弘 and 門之園 哲哉 and 近藤 科江},
  title = {発光イメージングによるがん転移機構の分子的解明},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745223,
  author = {Takahiro Kuchimaru and Satoshi Iwano and Masahiro Kiyama and Shun Mitsumata and Tetsuya Kadonosono and Haruki Niwa and Shojiro Maki and Shinae Kizaka-Kondoh},
  title = {A luciferin analog improves detection sensitivity of deep-tissue tumor using near-infrared bioluminescence},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745263,
  author = {北澤 舞花 and 門之園 哲哉 and 塩澤 唯 and 口丸 高弘 and 近藤 科江},
  title = {高性能な腫瘍標的結合ペプチドスクリーニング法の開発},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745264,
  author = {塩澤 唯 and 椿 卓也 and 桜井 史門 and 門之園 哲哉 and 口丸 高弘 and 近藤 科江},
  title = {光イメージングによる腫瘍関連骨髄系細胞の機能解析},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100745180,
  author = {門之園 哲哉 and 口丸 高弘 and 近藤 科江},
  title = {VASHドメイン構造により制御されるSVBP依存的細胞外分泌},
  booktitle = {},
  year = 2016,
}

@misc{CTT100787101,
  author = {門之園哲哉 and 近藤科江},
  title = {標的結合ペプチドの安定化方法},
  howpublished = {登録特許},
  year = 2021,
  month  = {},
  note   = {特願2017-559228(2016/12/28), 再表2017/115828(2018/10/18), 特許第6872797号(2021/04/22)}
}