@article{CTT100884134, author = {Hiroyuki Nakamura}, title = {DeepCubist: Molecular Generator for Designing Peptidomimetics Based on Complex Three-Dimensional Scaffolds}, journal = {}, year = 2022, } @article{CTT100883764, author = {S. Ogawa and Y. Asawa and M. Iiyama and A. Yoshimori and H. Nakamura and M. Oda}, title = {Regulation of binding between CD28 cytoplasmic region and SH2 domains of Grb2 and PI3K by carborane compounds for T-cell activation}, journal = {BIOORG. MED. CHEM. LETT.}, year = 2022, } @article{CTT100884135, author = {Hiroyuki Nakamura}, title = {Design of MMP-1 Inhibitors via SAR Transfer and Experimental Validation}, journal = {}, year = 2022, } @article{CTT100883765, author = {K. Umedera and T. Morita and H. Nakamura}, title = {Asymmetric construction of densely functionalized three-dimensional aza-tetracyclic scaffolds for drug discovery}, journal = {Chem. Commun}, year = 2022, } @article{CTT100884133, author = {A. G. Beck-Sickinger and D. P. Becker and O. Chepurna and B. Das and S. Flieger and E. Hey-Hawkins and N. Hosmane and S. S. Jalisatgi and H. Nakamura and R. Patil and M. da Graça and H. Vicente and C. Viñas}, title = {New Boron Delivery Agents}, journal = {Cancer Biother. Radiopharm.}, year = 2022, } @article{CTT100883550, author = {Kazuki Miura and Yijin Wen and Michihiko Tsushima and Hiroyuki Nakamura}, title = {Photodynamic therapy by glucose transporter 1–selective light inactivation}, journal = {ACS Omega}, year = 2022, } @article{CTT100877628, author = {K. Nishimura and S. Harrison and K. Kawai and T. Morita and K. Miura and S. Okada and H. Nakamura}, title = {Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor}, journal = {BIOORG. MED. CHEM. LETT.}, year = 2022, } @article{CTT100884132, author = {中村浩之}, title = {ホウ素の拓く創薬ワールド}, journal = {細胞「特集 低分子モダリティの進化―元素・光・分子機能に注目して」}, year = 2022, } @article{CTT100881362, author = {H. Kitamura and Y. Otake and N. Sugisawa and H. Sugisawa and T. Ida and H. Nakamura and S. Fuse and Hiroyuki Nakamura}, title = {Sequential Selective Introduction of Alcohols against Phosphorus Trichloride in a Continuous-Flow Reactor and Consideration of a Mechanism for Reduced Overreaction via the Addition of Imidazole}, journal = {Chemistry}, year = 2022, } @article{CTT100881360, author = {A. M.Hughes and J. A. Goldfinger and M. A. Palmieri and P. Ramos and I. S. Santa Cruz and L. De Leo and M. A. Garabalino and S. I. Thorp and P. Curotto and E. C.C. Pozzi and K. Kawai and S. Sato and M. E. Itoiz and V.A. Trivillin and J. S. Guidobono and H. Nakamura and A. E. Schwint}, title = {Boron neutron capture therapy (BNCT) mediated by maleimide-functionalized closo-dodecaborate albumin conjugates (MID:BSA) for oral cancer: Biodistribution studies and in vivo BNCT in the hamster cheek pouch oral cancer model}, journal = {Life (Basel)}, year = 2022, } @article{CTT100875492, author = {A. R Jalilian and A. Shahi and I. P. Swainson and H. Nakamura and M. Venkatesh and J. A. Osso Jr}, title = {Potential theranostic BNCT agents as multimodal radiopharmaceuticals}, journal = {Cancer Biotherapy and Radiopharmaceuticals}, year = 2022, } @article{CTT100875457, author = {S. Koyama and H. Sato and H. Sugai and M. Murakoshi and T. Kobayashi and S. Usami and K. Ikeda and Y. Haga and K. Tsumoto and H. Nakamura and N. Hirasawa and Kenji ISHIHARA and H. Wada}, title = {Effects of Salicylate Derivatives on Changes in Localization of H723R Pendrin Mutant Expressed in HEK293 Cells}, journal = {Auris Nasus Larynx}, year = 2022, } @article{CTT100875383, author = {Hiroyuki Nakamura}, title = {BODIPY Catalyzes Proximity‐Dependent Histidine Labellin}, journal = {}, year = 2022, } @article{CTT100875388, author = {R. Y. Utomo and S. Okada and A. Sumiyoshi and I. Aoki and H. Nakamura}, title = {Development of an MRI contrast agent for both detection and inhibition of the amyloid-β fibrillation process}, journal = {RSC Adv.}, year = 2022, } @article{CTT100865917, author = {Tae-Hee Han and M. K. Park and H. Nakamura and H. S. Ban}, title = {Capsaicin inhibits HIF-1α accumulation through suppression of mitochondrial respiration in lung cancer cells}, journal = {Biomedicine & Pharmacotherapy}, year = 2022, } @article{CTT100866095, author = {T. Morita and H. Murakami and Y. Asawa and H. Nakamura}, title = {Enantioselective Synthesis of Oxazaborolidines by Palladium-Catalyzed N−H/B−H Double Activation of 1,2-Azaborines}, journal = {Angew. Chem. Int. Ed.}, year = 2022, } @article{CTT100866098, author = {M. Tsushima and S. Sato and K. Miura and T. Niwa and HIDEKI TAGUCHI and H. Nakamura}, title = {Intracellular photocatalytic-proximity labeling for profiling protein–protein interactions in microenvironments}, journal = {Chem. Commun.}, year = 2022, } @article{CTT100866102, author = {R. Y. Utomo and A. Sugie and S. Okada and K. Miura and H. Nakamura}, title = {Detoxification of amyloid β fibrils by curcumin derivatives and their verification in a Drosophila Alzheimer's model}, journal = {Chem. Commun.}, year = 2022, } @article{CTT100864848, author = {G. Li and G. Yu and C. Wang and T. Morita and X. Zhang and H. Nakamura}, title = {Copper(I)-catalysed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N-propargylanilines with phosphites}, journal = {Org. biomol. chem.}, year = 2022, } @article{CTT100866101, author = {M. Tsuda and T. Morita and H. Nakamura}, title = {Synthesis of isoxazoloazaborines via gold(i)-catalyzed propargyl aza-Claisen rearrangement/borylative cyclization cascade}, journal = {Chem. Commun.}, year = 2022, } @article{CTT100865918, author = {H. Ueda and P.Wipf and H. Nakamura}, title = {Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities}, journal = {Bioorganic & Medicinal Chemistry}, year = 2022, } @inproceedings{CTT100884313, author = {中村浩之}, title = {BNCTの適応拡大を目指したホウ素薬剤開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100887611, author = {Hiroyuki Nakamura}, title = {Chemical Manipulation of Target Proteins Using Ruthenium bis(Bipyridine) Complexes}, booktitle = {}, year = 2022, } @inproceedings{CTT100884131, author = {Hiroyuki Nakamura}, title = {Development of Intracellular Photocatalytic Proximity Protein Labeling (iPPL) for Profiling Protein–Protein Interactions}, booktitle = {}, year = 2022, } @inproceedings{CTT100884130, author = {H. Nakamura and T. Morita and H. Murakami}, title = {Development of 1,2-Azaborine-fused Heterocycles and Their Novel Functionalization}, booktitle = {}, year = 2022, } @inproceedings{CTT100884012, author = {中村浩之}, title = {光触媒を用いた生細胞内標的タンパク質近接場標識法(iPPL 法)の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100884011, author = {中村浩之}, title = {ホウ素クラスターの創薬化学}, booktitle = {}, year = 2022, } @inproceedings{CTT100881420, author = {中村浩之}, title = {光反応を利用したタンパク質の化学修飾}, booktitle = {}, year = 2022, } @inproceedings{CTT100881419, author = {Taiki Morita and Hiroki Murakami and Hiroyuki Nakamura}, title = {Asymmetric Synthesis of Oxazaborolidines via Palladium-Catalyzed N-H/B-H Double Functionalization of 1,2-Azaborines}, booktitle = {}, year = 2022, } @inproceedings{CTT100881418, author = {Hiroyuki Nakamura and Yasunobu Asawa}, title = {Comprehensive Exploration of Chemical Space Using Trisubstituted Carboranes}, booktitle = {}, year = 2022, } @inproceedings{CTT100877626, author = {北村宙士 and 小竹佑磨 and 杉澤直斗 and 杉澤宏樹 and 井田朋智 and 中村浩之 and 布施新一郎}, title = {非対称リン酸トリエステルのマイクロフロー合成および反応機構解明}, booktitle = {}, year = 2022, } @inproceedings{CTT100877627, author = {北村宙士 and 小竹佑磨 and 杉澤直斗 and 杉澤宏樹 and 井田朋智 and 中村浩之 and 布施新一郎}, title = {非対称リン酸トリエステルのマイクロフロー合成および反応機構解明}, booktitle = {}, year = 2022, } @inproceedings{CTT100877625, author = {中村浩之 and 西村開 and 盛田大輝 and 岡田智 and 三浦一輝 and 柏木秀基 and 福尾祐介 and 松本孔貴 and 鈴木実 and 中井啓 and 川端信司}, title = {中性子捕捉療法のための血清アルブミンを利用したホウ素キャリアの開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100877624, author = {Hiroyuki Nakamura}, title = {Boron Delivery using Serum Albumin}, booktitle = {}, year = 2022, } @inproceedings{CTT100875469, author = {Rohmad Yudi Utomo and 杉江淳 and 岡田智 and 三浦一輝 and 中村浩之}, title = {Curcumin誘導体のアミロイドβ繊維の解離を介した解毒作用とショウジョウバエのアルツハイマー病モデルにおける検証}, booktitle = {}, year = 2022, } @inproceedings{CTT100875468, author = {西村開 and 盛田大輝 and 岡田智 and 三浦一輝 and 柏木秀基 and 福尾祐介 and 松本孔貴 and 高田卓志 and 鈴木実 and 中井啓 and 川端信司 and 中村浩之}, title = {中性子捕捉療法のための、アルブミンリガンドを基軸としたホウ素キャリアの開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875467, author = {社本乙華 and 小室敬史 and 杉澤直斗 and 中村浩之 and 布施新一郎}, title = {マイクロフローリアクター内での環状ペプチド合成法の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875466, author = {植原彩奈 and 盛田大輝 and 佐々木雄彦 and 中村浩之}, title = {リゾホスファチジルイノシトール(4,5)ビスリン酸の合成研究}, booktitle = {}, year = 2022, } @inproceedings{CTT100875464, author = {盛田大輝 and 中村浩之}, title = {ピペラジン酸およびN-ヒドロキシアミノ酸の直接縮合を基盤としたDentigerumycin Aの合成研究}, booktitle = {}, year = 2022, } @inproceedings{CTT100875463, author = {中村浩之 and Rohmad Yudi Utomo and 岡田智 and 住吉晃 and 青木 伊知男}, title = {アミロイドβ繊維化を検出・阻害するMRIプローブの開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875462, author = {村上弘樹 and 盛田大輝 and 中村浩之}, title = {パラジウム触媒を用いた1,2-アザボリン類の不斉N-H/B-H二官能基化法の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875461, author = {津田正仁 and 盛田大輝 and 中村浩之}, title = {金(I)触媒によるプロパルギルアザClaisen転位反応を用いたイソオキサゾロアザボリンの合成と亜鉛カルベノイドによるN−O結合へのメチレン挿入反応の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875460, author = {中村浩之}, title = {中性子捕捉療法:承認までの軌跡と今後の展望}, booktitle = {}, year = 2022, } @inproceedings{CTT100875459, author = {Hiroyuki Nakamura}, title = {Development of Intracellular Photocatalytic Proximity Protein Labeling (iPPL)}, booktitle = {}, year = 2022, } @inproceedings{CTT100875470, author = {三浦一輝 and Wen Yijin and 對馬 理彦 and 中村浩之}, title = {細胞透過型有機光触媒による標的タンパク質選択的不活性化と抗腫瘍活性プローブへの応用}, booktitle = {}, year = 2022, } @inproceedings{CTT100875458, author = {中村浩之}, title = {タンパク質夾雑空間解析のための細胞内光触媒近接場標識法(iPPL法)の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875357, author = {Michihiko Tsushima and Kazuki Miura and Shinichi Sato and Hiroyuki Nakamura}, title = {Intrecellular photocatalytic proximity labeling for profiling protein-protein interactins in multimolecular crowding}, booktitle = {}, year = 2022, } @misc{CTT100909669, author = {中村浩之 and 岡田智}, title = {新規蛍光検出薬}, howpublished = {公開特許}, year = 2023, month = {}, note = {特願2022-079168(2022/05/13), 特開2023-167748(2023/11/24)} } @misc{CTT100884602, author = {中村浩之 and 盛田大輝 and 岡田智 and 西村開 and 川端 信司 and 鰐渕 昌彦 and 福尾 祐介 and 柏木 秀基}, title = {新規ホウ素薬剤}, howpublished = {公開特許}, year = 2022, month = {}, note = {PCT/JP2022/010452(2022/03/10), WO 2022/191262(2022/09/15)} } @misc{CTT100884601, author = {布施新一郎 and 北村宙士 and 小竹佑磨 and 中村浩之}, title = {非対称型リン酸トリエステルの製造方法、対称型リン酸トリエステルの製造方法、リン酸エステルの製造方法、及び、有機リン化合物の製造方法}, howpublished = {公開特許}, year = 2022, month = {}, note = {PCT/JP2022/004557(2022/02/04), WO 2022/185843(2022/09/09)} } @misc{CTT100881786, author = {中村浩之 and 浅輪泰允 and 織田 昌幸}, title = {カルボラン化合物若しくはその塩又はこれらの溶媒和物}, howpublished = {公開特許}, year = 2022, month = {}, note = {PCT/JP2021/039442(2021/10/26), WO 2022/092068(2022/05/05)} } @misc{CTT100882394, author = {中村浩之 and 梅寺倖平 and 盛田大輝 and 小路 弘行 and 吉森 篤史}, title = {新規含窒素三環性骨格化合物およびその使用}, howpublished = {公開特許}, year = 2022, month = {}, note = {特願2020-204328(2020/12/09), 特開2022-091476(2022/06/21)} } @misc{CTT100835044, author = {中村浩之 and 佐藤伸一 and 深瀬 浩一}, title = {電気化学的手法を用いたハロゲン化物の製造方法}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2018-239130(2018/12/21), 特開2020-100865(2020/07/02), 特許第7166531号(2022/10/28)} } @misc{CTT100800020, author = {中村浩之}, title = {ホウ素含有葉酸誘導体}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2017-162387(2017/08/25), 特開2019-038778(2019/03/14), 特許第7154528号(2022/10/07)} }