"Keitaro Homma,Y. Miura*,M. Kobayashi,W. Chintrakulchai,M. Toyoda,K. Ogi,J. Michinishi,T. Ohtake,Y. Honda,T. Nomoto,H. Takemoto,N. Nishiyama","Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential",,"Sci. Technol. Adv. Mater.",,"Vol. 25","No. 1","pp. 233878",2024,Apr.
"Xin Shen,A. Dirisala,M. Toyoda,Yao Xiao,H. Guo,Y. Honda,T. Nomoto,H. Takemoto,Y. Miura,N. Nishiyama","pH-Responsive polyzwitterion covered nanocarriers for DNA delivery",,"J. Control. Release",,"Vol. 360",,"pp. 928-939",2023,July
"Haochen Guo,Xu Wen,Takahiro Nomoto,Kaito Kanamori,Yan Ming Voon,Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters.",,"Biomaterials",,"Vol. 293",,"pp. 121987",2023,Feb.
"Yuto Honda,Sayaka Onodera,Hiroyasu Takemoto,Faizah Noor,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Yudi Sun,Yutaka Miura,Nobuhiro Nishiyama","Thermo-responsive polymer-siRNA conjugates enabling artificial control of gene silencing around body temperature",,"Pharmaceutical Research",,"Vol. 40","No. 1","pp. 157-165",2022,Oct.
"Yijung Sung,Haochen Guo,Aria Ghasemizadeh,Xin Shen,Wanphiwat Chintrakulchai,Motoaki Kobayashi,Masahiro Toyoda,Koichi Ogi,Junya Michinishi,Tokoyuki Ohtake,Makoto Matsui,Yuto Honda,Takahiro Nomoto,Hiroyasu Takemoto,Yutaka Miura,Nobuhiro Nishiyama","Cancerous pH-responsive polycarboxybetaine-coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model",,"Cancer Science",,"Vol. 113","No. 12","pp. 4339-4349",2022,Oct.
"Aziz Awaad,Hiroyasu Takemoto,Muneaki Iizuka,Koichi Ogi,Yuki Mochida,Abdul-Hackam Ranneh,Masahiro Toyoda,Makoto Matsui,Takahiro Nomoto,Yuto Honda,Kotaro Hayashi,Keishiro Tomoda,Tomoyuki Ohtake,Yutaka Miura,Nobuhiro Nishiyama","Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration",,"Journal of Controlled Release",,"Vol. 346",,"pp. 392-404",2022,May
"Yuto Honda*,Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yutaka Miura,Nobuhiro Nishiyama*","Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity",,"ACS Applied Materials and Interfaces",,"Vol. 13","No. 46","pp. 54850?54859",2021,Nov.
"Yuto Honda*,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Kaori Taniwaki,Haochen Guo,Yutaka Miura,Nobuhiro Nishiyama*","Systemically Applicable Glutamine-Functionalized Polymer Exerting Multivalent Interaction with Tumors Overexpressing ASCT2.",,"ACS Applied Bio Materials",,"Vol. 4","No. 10","pp. 7402?7407",2021,Aug.
"Takahiro Nomoto,Ying Yao,Yukiya Inoue,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy",,"Journal of Controlled Release",,"Vol. 332",,"pp. 184-193",2021,Feb.
"Komoto Kana,Takahiro Nomoto,Muttaqien S.,Takemoto Hiroyasu,Matsui Makoto,Miura Yutaka,Nishiyama Nobuhiro","Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine",,"Cancer Science",,"Vol. 112","No. 1","pp. 410-421",2021,Jan.
"S Muttaqien,Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Photodynamic therapy using LCST polymers exerting pH-responsive isothermal phase transition",,"Journal of Controlled Release",,"Vol. 328",,"pp. 608-616",2020,Dec.
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Nobuhiro Nishiyama","多価環状RGDペプチド担持高分子型光増感剤によるphotochemical internalizationの検討","LASER WEEK IN KOCHI",,,,,,2020,Oct.
"Yuto Honda,Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yuka Kaihara,Yutaka Miura,Nobuhiro Nishiyama","Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery",,"Biomacromolecules",,"Vol. 21","No. 9","pp. 3826-3835",2020,Sept.
"Xiaohang Sun,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Haochen Guo,Yudi Sun,Yutaka Miura,Nobuhiro Nishiyama","Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives",,"Journal of Controlled Release",,,,,2020,Sept.
"Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","高分子修飾によるsiRNA周囲の空間支配と薬理機構制御",,,,,,,2020,Sept.
"Masahiro Toyoda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","腫瘍内pH応答性の獲得を目指した高分子ベタイン内の両イオン性基の種類・間隔の検討",,,,,,,2020,Sept.
"Yudi Sun,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","ASO-分岐PEG結合体を内包する小分子キャリアの開発および機能評価",,,,,,,2020,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Kakeru Konarita,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Development of functional polymers to boost therapeutic potential of boronophenylalanine in neutron capture therapy","第69回高分子討論会",,,,,,2020,Sept.
"Kana Komoto,Takahiro Nomoto,S Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","がん鉄キレート療法のための効率的な除鉄を実現する機能性高分子の開発","第69回高分子討論会",,,,,,2020,Sept.
"I Dewa Agung Panji Dwipayana,Yuto Honda,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Development of a versatile drug delivery system using tannic acid and boronic acid-conjugated polymer","第69回高分子討論会",,,,,,2020,Sept.
"ムツタキンシャイクリザルエル,Yutaka Miura,Haochen Guo,Takahiro Nomoto,Kana Komoto,S Muttaqien,Xiaohang Sun,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Polymeric iron-chelators for improving high- dose vitamin C therapy","第69回高分子討論会",,,,,,2020,Sept.
"Haochen Guo,Takahiro Nomoto,Kana Komoto,S Muttaqien,Xiaohang Sun,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Effect of polymeric iron-chelators on high-dose vitamin C therapy","第36回日本DDS学会学術集会",,,,,,2020,Aug.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama",""環状アセタール構造に基づくゲムシタビン担持型高分子の開発とその機能評価 および副作用低減"","第36回日本DDS学会学術集会",,,,,,2020,Aug.
"Guo Haochen,Takahiro Nomoto,Kana Komoto,Sun Xiaohang,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Development of polymeric iron-chelators for enhancing high-dose vitamin C therapy","第 3 回 COI 学術交流会",,,,,,2020,July
"Takahiro Nomoto,Yuto Honda,Yuka Kaihara,Hiroaki Kinoh,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","タンニン酸とボロン酸ケミストリーを利用した高分子複合体の簡便調製法","第 3 回 COI 学術交流会",,,,,,2020,July
"Takahiro Nomoto,Sjaikhurrizal El Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Photodynamic therapy utilizing functional polymers that exert pH-responsive isothermal phase transition","ICPST-36",,,,,,2020,June
"Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama",""環状アセタール構造を介したゲムシタビンのポリアミノ酸への導入と薬効増大 および副作用低減"",,,,,,,2020,May
"Masahiro Toyoda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","高分子ベタイン内のイオン性基の種類・間隔の制御と腫瘍内pH応答性への展開","第69回高分子学会年次大会",,,,,,2020,May
"Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Iron chelation cancer therapy using functional polymers targeting tumors","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb.
"Yuto Honda,Takahiro NOMOTO,Makoto MATSUI,Hiroyasu TAKEMOTO,Yuka KAIHARA,Yutaka MIURA,Nobuhiro NISHIYAMA","Development of intracellular pH- responsive protein delivery system utilizing boronic acid-conjugated polymer and tannic acid","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(vinyl alcohol) for enhancing therapeutic effects of p-boronophenylalanine in neutron capture therapy","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb.
"Hiroyasu Takemoto","がん組織内環境を認識する機能性高分子の開発と被覆ナノ粒子への展開",,"Drug Delivery System DDS",,"Vol. 35","No. 1","pp. 84-85",2020,Jan.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,M Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism",,"Science Advances",,"Vol. 6","No. 4",,2020,Jan.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Gyomon Ryu,Masahiro Toyoda,Yuto Honda,Kaori Taniwaki,Naoki Yamada,Junhyun Kim,Keishiro Tomoda,Nobuhiro Nishiyama","Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects",,"Biomaterials",,"Vol. 235",,,2020,
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Photosensitizer delivery to tumor cells and tumor-associated vasculature using functional polymers","7th International ALA and Prophyrin Symposium (IAPS7)",,,,,,2019,Dec.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","生体適合性高分子とボロノフェニルアラニンから構成される中性子捕捉療法用代謝制御型ホウ素送達システム","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","がん治療のための効率的な生体内の除鉄を実現する機能性高分子の開発","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yuka Kaihara,Yutaka Miura,Nobuhiro Nishiyama","ボロン酸導入高分子とタンニン酸を用いた細胞内環境応答タンパク質送達システムの構築","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","環状アセタール構造に基づくゲムシタビンの高分子修飾と制がん効果増大及び副作用低減","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov.
"Hiroyasu Takemoto,Muhammad Aziz,Ranneh Hackam,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","腫瘍内pH応答性高分子ベタインの設計と被覆ナノ粒子への展開","第68回高分子討論会",,,,,,2019,Sept.
"Takahiro Nomoto,S Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","腫瘍内低pH環境に応答して親水-疎水相転移挙動を示す高分子コンジュゲート型光増感剤","PhotoDynamic Medicine 2019",,,,,,2019,Sept.
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","温度応答性高分子-siRNA結合体の合成と外部刺激によるsiRNAの生物活性制御","第68回高分子討論会",,,,,,2019,Sept.
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん細胞の高密度グルタミントランスポーターと選 択的な相互作用を示す機能性高分子の開発","第68回高分子討論会",,,,,,2019,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","生体適合性高分子とp-boronophenylalanineから構成されるホウ素送達システムの開発と構成高分子の物性が体内動態と治療効果に与える影響に関する考察","第16回日本中性子捕捉療法学会",,,,,,2019,Sept.
"Kaito Kanamori,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","BPA delivery system utilizing sugar-modified polymers forming stable boronate esters","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)",,,,,2019,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Makoto Matsui,Hiroyasu Takemoto,Nobuhiro Nishiyama","Boosting Therapeutic Potential of p-Boronophenylalanine Using Biocompatible Polymers","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)",,,,,,2019,Sept.
"Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","がん治療を指向した生体内鉄イオンをキレートする機能性高分子の開発","第35回日本DDS学会学術集会",,,,,,2019,July
"Hiroyasu Takemoto,Muhammad Aziz,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","腫瘍 pH 応答性高分子ベタインの開発とナノ粒子のがん送達への展開","第35回日本DDS学会学術集会",,,,,,2019,July
"Makoto Matsui,Yuka Kaihara,Hiroyasu Takemoto,Takahiro Nomoto,Nobuhiro Nishiyama","薬物送達技術を応用した新規骨折治療法の開発","第35回日本DDS学会学術集会",,,,,,2019,July
"Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","ボロン酸エステルを利用したホウ素薬物送達キャリアの開発","第35回日本DDS学会学術集会",,,,,,2019,July
"Nobuhiro Nishiyama,Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui","Development of polymeric iron chelator for cancer therapy","The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics",,,,,,2019,July
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","温度応答性高分子-siRNA結合体とのポリイオンコンプレックス形成と外部刺激によるsiRNA の薬効制御",,,,,,,2019,July
"Hiroyasu Takemoto,Wang, Chih-Ling,Takahiro Nomoto,Matsui, Makoto,Tomoda, Keishiro,Nobuhiro Nishiyama","Pyruvate responsiveness based on α-oxohydrazone formation for intracellular siRNA release from polyion complex-based carriers",,"Biomacromolecules",,,,,2019,May
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん細胞の高密度グルタミントランスポーターを標的として選択的な相互作用を示す機能性高分子の開発","第68回高分子学会年次大会",,,,,,2019,May
"Masahiro Toyoda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","腫瘍内pH応答性高分子ベタイン内のイオン性基間距離の検討","第68回高分子学会年次大会",,,,,,2019,May
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","ポリイオンコンプレックスを利用した温度応答性高分子-siRNA結合体の細胞内導入と外部刺激によるsiRNAの生物活性制御","第68回高分子学会年次大会",,,,,,2019,May
"Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","糖修飾高分子とホウ素薬物から構成される薬物送達システムの開発","第68回高分子学会年次大会",,,,,,2019,May
"Watanabe, Sumiyo,Hayashi, Kotaro,Toh, Kazuko,Kim Hyun Jin,Liu, Xueying,Chaya, Hiroyuki,Fukushima, Shigeto,Katsushima, Keisuke,Kondo, Yutaka,Uchida, Satoshi,Ogura, Satomi,Takahiro Nomoto,Hiroyasu Takemoto,Cabral, Horacio,Kinoh, Hiroaki,Tanaka, Hiroyoshi,Kano, Mitsunobu,Matsumoto, Yu,Fukuhama, Hiroshi,Uchida, Shyunya,Nagaku, Masaomi,Osada, Kensuke,Nobuhiro Nishiyama,Miyata, Kanjiro,Kataoka, Kazunori","In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers",,"Nature Communications",,,,,2019,Apr.
"Hiroyasu Takemoto","抗体とDDS",,"ドラッグキャリア設計入門 DDSからナノマシンまで","丸善出版",,"  第3章","pp. 125",2019,Jan.
"Hiroyasu Takemoto","バイオシグナルに応答する高分子の設計と薬物送達キャリアへの展開",,"ドラッグキャリア設計入門 DDSからナノマシンまで","丸善出版",,"  第2章","pp. 68-76",2019,Jan.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Metabolism-controlled boron delivery systems composed of biocompatible polymers and boronophenylalanine for neutron capture therapy",,"Abstracts of Papers of the American Chemical Society",,,,,2019,
"Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Boron Delivery Using Sugar-Modified Polymers for Neutron Capture Therapy","The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics",,,,,,2019,
"Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety",,"BIOMACROMOLECULES",,"Vol. 20","No. 4","pp. 1493-1504",2018,Dec.
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Conjugation of siRNA and a polymer with coil-globule transition property for control of siRNA activity around body temperature","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Yuka Kaihara,Makoto Matsui,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Development of novel drug delivery system for enhancing bone regeneration in bone fracture model mouse","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Yuto Honda,Naoki Yamada,Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism.","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Hiroyasu Takemoto,Abdul-Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","Ethylenediamine-based polyzwitterion that becomes cationic at tumorous pH for effective tumor accumulation of the coated nanomaterials","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Sjaikhurrizal El Muttaqien,松井 誠,武元 宏泰,野本 貴 大,友田 敬士郎,西山 伸宏","Poly(N-isopropylacrylamide) derivatives exering remarkable LCST shift in response to slight pH chnge via detachment of hydrophilic acid-labile moiety","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Sun Xiaohang,Taknaori Inaba,Kazuki Ohsakama,Mika Shishido,Hiroki Yoshioka,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","Development of degradable poly(ethylene glycol)(PEG) derivatives for suppressing cellular vacuolations","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of poly(amino acid)-based carrier that loads gemcitabine via reversible linkage and its evaluation using pancreatic cancer model","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Metabolism-controlled boron delivery systems composed of p-boronophenylalanine and poly(vinyl alcohol)","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct.
"Ying Yao,Takahiro Nomoto,Yukiya Inoue,Minoru Suzuki,Makoto Matsui,Hiroyasu Takemoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced tumor-targeted delivery of p-boronophenylalanine using fructose-functionalized polymers for boron neutron capture therapy","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct.
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Multiple cyclic RGD-conjugated functional polymers controlling intratumoral distribution of IRDye 700DX","Photodynamic Therapy and Photodiagnosis Update 2018",,,,,,2018,Sept.
"Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","生体適合性機能性高分子によるボロノフェニルアラニンの代謝制御と治療効果の向上","第15回日本中性子捕捉療法学会学術大会",,,,,,2018,Sept.
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","グルタミン代謝が亢進したがん細胞の高密度グルタ ミントランスポーターを認識してアフィニティを示す機能性高 分子","第67回高分子討論会",,,,,,2018,Sept.
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of gemcitabine-conjugated poly(amino acid) and its evaluation using pancreatic tumor model","第67回高分子討論会",,,,,,2018,Sept.
"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","Size-regulated siRNA carriers from small complex loading single siRNA molecule for systemic delivery to tumor tissue","第77回日本癌学会学術総会",,,,,,2018,Sept.
"R. Toshiyama R,M. Konno,H. Eguchi,H. Takemoto,T. Noda,A. Asai,J. Koseki,N. Haraguchi,Y. Ueda,K. Matsushita,K. Asukai,T. Ohashi,Y. Iwagami,D. Yamada,D. Sakai,T. Asaoka,T. Kudo,K. Kawamoto,K. Gotoh,S. Kobayashi,T. Satoh,Y. Doki,N. Nishiyama,M. Mori,H. Ishii","Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells",,"Oncogene",,"Vol. 38","No. 2","pp. 244-260",2018,Aug.
"Sjaikhurrizal El Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor","256th ACS National Meeting & Exposition",,,,,,2018,Aug.
"Hiroyasu Takemoto,Abduhl Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials","256th ACS National Meeting & Exposition",,,,,,2018,Aug.
"Hiroyasu Takemoto","Development of polyzwitterion that recognizes tumorous pH for effective delivery of the coated nanoparticles","3rd Bone and Biomaterials Workshop",,,,,,2018,June
"Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討","第34回日本DDS学会学術集会",,,,,,2018,June
"Hiroyasu Takemoto","Bioresponsive Polyzwitterion that Recognizes Tumorous pH for a Construction of Tumor-Targeted Carriers","The 35th International Conference of Photopolymer Science and Technology",,,,,,2018,June
"Ying Yao,Takahiro Nomoto,Yukiya Inoue,Minoru Suzuki,Makoto Matsui,Hiroyasu Takemoto,Keishiro Tomoda,Nobuhiro Nishiyama","Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy","第34回日本DDS学会学術集会",,,,,,2018,June
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","可逆的にゲムシタビンを担持するポリアミノ酸型キャリアの開発とすい臓がんモデルでの機能評価","第67回高分子年次大会",,,,,,2018,May
"Hiroyasu Takemoto,Ranneh Abdul-Hackam,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Yuki Mochida,Mitsuru Naito,Nobuhiro Nishiyama","腫瘍内環境を認識する高分子ベタインの開発とナノ粒子の効率的な腫瘍集積への展開","第67回高分子年次大会",,,,,,2018,May
"Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","siRNAへのCoil-globule挙動を有する高分子の結合と生体温度付近での遺伝子発現抑制能の精密制御","第67回高分子年次大会",,,,,,2018,May
"X. Dou,T. Nomoto,H. Takemoto,M. Matsui,K. Tomoda,N. Nishiyama","Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers",,"Scientific Reports",,"Vol. 8","No. 1","pp. 8126",2018,May
"A.-H. Ranneh,H. Takemoto,S. Sakuma,A. Awaad,T. Nomoto,Y. Mochida,M. Matsui,K. Tomoda,M. Naito,N. Nishiyama","An ethylenediamine-based switch to control the polyzwitterion charge at tumorous pH for effective tumor accumulation of coated nanomaterials",,"Angewandte Chemie International Edition",,"Vol. 57","No. 18","pp. 5057",2018,Apr.
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Glutamine-Functionalized Polymer for Tumor-Selective High Affinity by Sensing Dense Glutamine Transporters Associated with Aberrant Metabolism","14th US-JAPAN Symposium on Drug Delivery Systems",,,,,,2017,Dec.
"H. Takemoto,N. Nishiyama","Functional polymer-based siRNA delivery carrier that recognizes site- specific biosignals",,"Journal of Controlled Release",,"Vol. 267",,,2017,Dec.
"Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate","14th US-JAPAN Symposium on Drug Delivery Systems",,,,,,2017,Dec.
"Hiroyasu Takemoto,Nobuhiro Nishiyama","Construction of siRNA-polymer conjugate and its biological application","IUMRS-ICA2017",,,,,,2017,Nov.
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん選択的に相互作用するグルタミン担持高分子の創製と機能評価","第39回日本バイオマテリアル学会大会",,,,,,2017,Nov.
"Xuebo Dou,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","光増感剤結合型高分子における多岐環状ＲＧＤペプチドの腫瘍集積性と腫瘍内分布への効果の検討","第66回高分子討論会",,,,,,2017,Sept.
"Shunya Sakuma,Abdul-Hackam RANNEH,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","腫瘍指向性ステルス高分子の開発とDDSへの応 用-ベタイン構造内アニオン性基の影響-","第66回高分子討論会",,,,,,2017,Sept.
"Hiroki Shinkai,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発","第66回高分子討論会",,,,,,2017,Sept.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減","第66回高分子討論会",,,,,,2017,Sept.
"Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上","Photopolymer Science and Technology (ICPST-34)",,,,,,2017,July
"N. Yamada,Y. Honda,H. Takemoto,T. Nomoto,M. Matsui,K. Tomoda,M. Konno,H. Ishii,M. Mori,N. Nishiyama","Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism",,"Scientific Reports",,"Vol. 7","No. 1","pp. 6077",2017,July
"Hiroyasu Takemoto,Huang Chih-Hao,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-Nitrobenzenesulfonamide Group that Responds to Intracellular Redox Potential with Enhanced Photostability for a Construction of Polymer-siRNA Conjugate System","The 34th International Conference of Photopolymer Science and Technology (ICPST-34)",,,,,,2017,June
"Hiroki Shinkai,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発","第66回高分子年次大会",,,,,,2017,May
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters","第66回高分子年次大会",,,,,,2017,May
"Hiroyasu Takemoto,Chih Hao Huang,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system","第66回高分子年次大会",,,,,,2017,May
"Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発","第66回高分子年次大会",,,,,,2017,May
"Shunya Sakuma,Ranneh Hackam,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-","第66回高分子年次大会",,,,,,2017,May
"Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism.","253rd American Chemical Society National Meeting & Exposition",,,,,,2017,Apr.
"Hiroyasu Takemoto,Huang Chih-Hao,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate.","253rd American Chemical Society National Meeting & Exposition",,,,,,2017,Apr.
"Hiroyasu Takemoto,Hyun Jin Kim,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","単分子siRNA内包型小会合体を要素とするsiRNAキャリアの構築と全身投与による腫瘍組織への送達","日本薬学会第137年会",,,,,,2017,Mar.
"Ranneh Hackam,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of stealth shell based on polycarboxybetaine structure tuned to selectively interact with cells in tumor extracellular acidic pH","日本薬学会第137年会",,,,,,2017,Mar.
"Takanori Inaba,Hiroyasu Takemoto,Makoto Matsui,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced antitumor activity and reduced gastrointestinal toxicity of gemcitabine based on conjugation with biocompatible polymer via acetal linker","International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)",,,,,,2017,Mar.
"?Tsukasa Nishimori,Naoki Yamada,Hiroyasu Takemoto,Kentaro Suina,Juntaro Yamasaki,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Osamu Nagano,Hideyuki Saya,Nobuhiro Nishiyama","Development of intravenously injectable sulfasalazine derivatives to treat stem-like cancer cells","International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)",,,,,,2017,Mar.
"Mitsuru Naito,Ryota Azuma,Hiroyasu Takemoto,Mao Hori,Naoto Yoshinaga,Shigehito Osawa,Rimpei Kamegawa,Hyun Jin Kim,Takehiko Ishii,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori","Multilayered Polyion Complexes with Dissolvable Silica Layer Covered by Controlling Densities of cRGD-conjugated PEG Chains for Cancer-targeted siRNA Delivery",,"Journal of Biomaterials Science, Polymer Edition",,"Vol. 28",,"pp. 1109-1123",2017,Mar.
"Shigehito Osawa,Takehiko Ishii,Hiroyasu Takemoto,Kensuke Osada,Kazunori Kataoka","A facile amino-functionalization of poly(2-oxazoline)s’ distal end through sequential azido end-capping and Staudinger reactions",,"European Polymer Journal",,"Vol. 88",,"pp. 553-561",2017,Feb.
"Chi-Hao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group as a new chemical linker with redox sensitivity for siRNA-conjugated polymer system","11th Annual Symposium on Nanobiotechnology 2017",,,,,,2017,Feb.
"Chih-Hao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Utility of 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-conjugated Polymer System",,"ChemMedChem",,"Vol. 12","No. 1","pp. 19-22",2017,Jan.
"Hiroyasu Takemoto","第33回日本DDS学会学術集会",,"Drug delivery system","日本DDS学会","Vol. 32","No. 4","pp. 348-349",2017,
"Chihhao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzensulfonamide groups as a chemical linker with enhanced extracellular stability and redox-sensitive cleavability for siRNA-conjugated polymer system","The 11th SPSJ International Polymer Conference (IPC2016)",,,,,,2016,Dec.
"Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Artificial control of siRNA bioactivity based on the phase transition behavior of the conjugated polymeric molecule","The 11th SPSJ International Polymer Conference (IPC2016)",,,,,,2016,Dec.
"Hiroyasu Takemoto,Kanjiro Miyata,Kotaro Hayashi,Yuki Mochida,Kazunori Kataoka,Nobuhiro Nishiyama","シロキサンネットワークにて形成されるsiRNA内包有機-無機ハイブリッドナノ粒子の開発","日本バイオマテリアル学会シンポジウム 2016",,,,,,2016,Nov.
"Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel glutamine-based polymeric ligand for transporter-mediated tumor targeting","3rd International Conference on Biomaterials Science in Tokyo",,,,,,2016,Nov.
"越後真梨那,Hiroyasu Takemoto,Kotaro Hayashi,Kanjiro Miyata,金澤秀子,Kazunori Kataoka,Nobuhiro Nishiyama","がん細胞内にて特異的に切断される Linker を利用した siRNA 送達キャリアの開発","日本バイオマテリアル学会シンポジウム 2016",,,,,,2016,Nov.
"Xiaohang Sun,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","がんへの薬剤の集積状態をレポートするナノメディシンの開 発","第65回高分子討論会",,,,,,2016,Sept.
"Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Development of siRNA-conjugated polymer with coil-globule transition behavior for an artificially controlled gene silencing activity","第65回高分子討論会",,,,,,2016,Sept.
"Chih Ling Wang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","A Novel Design of Polyion Complex (PIC) with The Pyruvate-Reactive Function toward Enhanced Cytosolic Release of siRNA","第65回高分子討論会",,,,,,2016,Sept.
"Yi Yu,Hyun Jin Kim,Peng Mi,Meng Zheng,Hiroyasu Takemoto,Kazuko Toh,Kim Beob Soo,Kotaro Hayashi,Mitsuru Naito,Yu Matsumoto,Kanjiro Miyata,Kazunori Kataoka","Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.",,"Journal of Controlled Release","Elsevier",,,,2016,Sept.
"Junhyun Kim,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","高分子ミセルにおける内核構造の安定性の差異がもたらす腫瘍集積性に関する考察","第65回高分子討論会",,,,,,2016,Sept.
"Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil?Globule Transition Behavior",,"Bioconjugate Chemistry",,,,,2016,Aug.
"NOOR,Hiroyasu Takemoto,Takahiro Nomoto,Nobuhiro Nishiyama","Development of thermoresponsive polymer-siRNA conjugates for controlled RNAi activity","第６５回高分子学会年次大会",,,,,,2016,May
"Chih-Ling,Hiroyasu Takemoto,Nobuhiro Nishiyama","Programmed siRNA Release based on α-Oxohydrazone Chemistry for Polyion complex-based siRNA Delivery System","第６５回高分子学会年次大会",,,,,,2016,May
"Kotaro Hayashi,Hiroyuki Chaya,Shigeto Fukushima,Sumiyo Watanabe,Hiroyasu Takemoto,Kensuke Osada,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers",,"Macromolecular Rapid Communications",,"Vol. 37","No. 6","pp. 486-493",2016,Jan.
"Kotaro Hayashi,Hiroyuki Chaya,Shigeto Fukushima,Sumiyo Watanabe,Hiroyasu Takemoto,Kensuke Osada,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Macromol. Rapid Commun. 6/2016.",,"Macromolecular rapid communications",,"Vol. 37","No. 6","pp. 560",2016,Jan.
"Meng Zheng,Hyun Jin Kim,Hiroyasu Takemoto,Kanjiro Miyata,Kazunori Kataoka","Precisely regulated nanoarchitecture comprised of gold nanotemplate and unimer polyion complex for systemic delivery of siRNA",,"Journal of Controlled Release",,"Vol. 213",,"pp. E75-E76",2015,
"Hiroyasu Takemoto,Nobuhiro Nishiyama","ジブロックコポリマーを基盤とする高分子ミセル型制がん剤送達キャリア",,"DDSキャリア作成プロトコル集",,,,"  73-79",2015,
"Hui Gao,Hiroyasu Takemoto,Qixian Chen,Mitsuru Naito,Hirokuni Uchida,Xueying Liu,Kanjiro Miyata,Kazunori Kataoka","Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity",,"Chemical Communications",,"Vol. 51","No. 15","pp. 3158-3161",2015,
"Hiroyasu Takemoto,Nobuhiro Nishiyama","Design of Functional Polymers for Intracellular Nucleic Acids Delivery",,"Intracellular Delivery Ii: Fundamentals and Applications",,"Vol. 7",,"pp. 207-217",2014,
"Hiroyasu Takemoto,Nobuhiro Nishiyama,Kazunori Kataoka","凍結濃縮現象によるClick反応加速",,"クリックケミストリー?基礎から実用まで-（ファインケミカルシリーズ）",,,,"  184-191",2014,
"Hyun Jin Kim,Hiroyasu Takemoto,Yi Yu,Meng Zheng,Yoshinori Maeda,Hiroyuki Chaya,Kotaro Hayashi,Peng Mi,Frederico Pittella,Christie James,Kazuko Toh,Yu Mastumoto,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles",,"Acs Nano",,"Vol. 8","No. 9","pp. 8979-8991",2014,
"Frederico Pittella,Cabral Horacio,Yoshinori Maeda,Peng Mi,Sumiyo Watanabe,Hiroyasu Takemoto,Hyun Jin Kim,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles",,"Journal of Controlled Release",,"Vol. 178",,"pp. 18-24",2014,
"Nobuhiro Nishiyama,Hiroyasu Takemoto","Polymeric Micelles",,"Encyclopedia of Polymeric Nanomaterials",,,,,2014,
"Shigehito Osawa,Kensuke Osada,Shigehiro Hiki,Anjaneyulu Dirisala,Hiroyasu Takemoto,Takehiko Ishii,Kazunori Kataoka","Design of poly(oxazoline) based triblock copolymer for polyplex micelles with core protective parisade",,"Abstracts of Papers of the American Chemical Society",,"Vol. 248",,,2014,
"Yoshinori Maeda,Frederico Pittella,Takahiro Nomoto,Hiroyasu Takemoto,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles",,"Macromolecular Rapid Communications",,"Vol. 35","No. 13","pp. 1211-1215",2014,
"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","Bioresponsive Polymer-Based Nucleic Acid Carriers",,"Nonviral Vectors For Gene Therapy Lipid- and Polymer-Based Gene Transfer",,"Vol. 88",,"pp. 289-323",2014,
"Hiroyasu Takemoto,Kanjiro Miyata,Shota Hattori,Takehiko Ishii,Tomoya Suma,Satoshi Uchida,Nobuhiro Nishiyama,Kazunori Kataoka","Acidic pH-Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosomal Escape with Reduced IFN alpha-Associated Immune Response",,"Angewandte Chemie-International Edition",,"Vol. 52","No. 24","pp. 6218-6221",2013,
"Kanjiro Miyata,Christie James,Tomoya Suma,Hiroyasu Takemoto,Hirokuni Uchida,Nobuhiro Nishiyama,Kazunori Kataoka","Fine-Tuning of Repeating Aminoethyelene Units in Poly(aspartamide) Side Chains for Enhanced siRNA Delivery",,"Tailored Polymer Architectures For Pharmaceutical and Biomedical Applications",,"Vol. 1135",,"pp. 189-196",2013,
"Hiroyasu Takemoto,Kanjiro Miyata","生体内還元環境とそれに応答する薬剤キャリア設計",,"遺伝子医学MOOK別冊 ここまで広がるドラッグ徐放技術の最前線 古くて新しいドラッグデリバリーシステム",,,,"  351-356",2013,
"Hiroyasu Takemoto,Kanjiro Miyata,Takehiko Ishii,Shota Hattori,Shigehito Osawa,Nobuhiro Nishiyama,Kazunori Kataoka","Accelerated Polymer-Polymer Click Conjugation by Freeze-Thaw Treatment",,"Bioconjugate Chemistry",,"Vol. 23","No. 8","pp. 1503-1506",2012,
"Tomoya Suma,Kanjiro Miyata,Yasutaka Anraku,Sumiyo Watanabe,Christie James,Hiroyasu Takemoto,Momoko Shioyama,Noha Gouda,Takehiko Ishii,Nobuhiro Nishiyama,Kazunori Kataoka","Smart Multilayered Assembly for Biocompatible siRNA Delivery Featuring Dissolvable Silica, Endosome-Disrupting Polycation, and Detachable PEG",,"Acs Nano",,"Vol. 6","No. 8","pp. 6693-6705",2012,
"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","siRNA-grafted polymer for efficient siRNA delivery system",,"Abstracts of Papers of the American Chemical Society",,"Vol. 243",,,2012,
"Kanjiro Miyata,Takahiro Nomoto,Hiroyasu Takemoto,Hyun Jin Kim,Yu Matsumoto,Makoto Oba,Nobuhiro Nishiyama,Kazunori Kataoka","Development of advanced polymer-based nanodevices for nucleic acids delivery",,"Abstracts of Papers of the American Chemical Society",,"Vol. 240",,,2010,
"Kanjiro Miyata,Noha Gouda,Hiroyasu Takemoto,Makoto Oba,Yan Lee,Hiroyuki Koyama,Yuichi Yamasaki,Keiji Itaka,Nobuhiro Nishiyama,Kazunori Kataoka","Enhanced transfection with silica-coated polyplexes loading plasmid DNA",,"Biomaterials",,"Vol. 31","No. 17","pp. 4764-4770",2010,
"Hiroyasu Takemoto,Atsushi Ishii,Kanjiro Miyata,Masataka Nakanishi,Makoto Oba,Takehiko Ishii,Yuichi Yamasaki,Nobuhiro Nishiyama,Kazunori Kataoka","Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system",,"Biomaterials",,"Vol. 31","No. 31","pp. 8097-8105",2010,