"Natsuki Shibukawa,Kana Sasamoto,瀬尾 秀宗,Takanobu Yasuda,Bo Zhu,太田 邦史,Hiroshi Ueda,Tetsuya Kitaguchi","バイオセンサーに変換可能な抗体の取得に向けた蛍光プローブタンパク質の開発","化学工学会第89年会",,,,,,2024,Mar. "Bo Zhu,Takanobu Yasuda,Tetsuya Kitaguchi","切らずに開く酵素スイッチ",,"日本化学会バイオテクノロジー部ニュースレター",,"Vol. 27","No. 2","Page 3-11",2024,Mar. "Akihito Inoue,Bo Zhu,Takanobu Yasuda,Keisuke Mizutani,Ken Kobayashi,Tetsuya Kitaguchi","タンパク質言語モデルを用いた一変異効果予測による蛍光免疫センサーの機能向上","化学工学会第89年会",,,,,,2024,Mar. "Bo Zhu,Yukihiko Yamasaki,Takanobu Yasuda,Cheng Qian,Zhirou Qiu,Hiroshi Ueda,Tetsuya Kitaguchi","A customizable one-pot detection system using β-glucuronidase switch and label-free antibody","化学工学会第89年会",,,,,,2024,Mar. "Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","発光酵素断片のトラップ&リリースに基づく抗原検出法","化学工学会第89年会",,,,,,2024,Mar. "Takanobu Yasuda,Tetsuya Kitaguchi","互いに引き合う螺旋状ペプチド ?二量体形成から細胞療法まで?",,"アグリバイオ","北隆館","vol. 8","No. 1","pp. 85-91",2024,Jan. "Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","生物発光免疫センサーの発光活性増大機構の解明とその原理の 全長抗体への展開","第2回日本抗体学会学術大会","第2回日本抗体学会学術大会要旨集",,,,,2023,Nov. "Keisuke Mizutani,Ken Kobayashi,Bo Zhu,Tetsuya Kitaguchi,Akihito Inoue","教師なしクラスタリングを用いたタンパク質機能予測","第26回情報論的学習理論ワークショップ (IBIS2023)",,,,,,2023,Oct. "岡田航輝,間部悟司,加藤晃代,Bo Zhu,Tetsuya Kitaguchi,中野秀雄","出芽酵母における翻訳促進ペプチドタグに関する研究","日本農芸化学会 中部・関西支部合同大会",,,,,,2023,Oct. "Kana Sasamoto,Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","Efficient and rapid linker optimization with heterodimeric coiled coils improves the response of fluorescent biosensors comprising antibody and protein M",,"The Analyst",,"vol. 148",,"p. 5843-5850",2023,Oct. "Zhu, B.,Qiu, Z.,Mizutani, K.,Kobayashi, K.,Ueda, H.,Kitaguchi, T.","Rapid development of single fluorescent protein-based immunosensor Flashbody through ultra-high-throughput screening and cell-free protein synthesis","第75回?本?物?学会?会",,,,,,2023,Sept. "Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","抗体結合タンパク質を利用した全長抗体の生物発光センサー化","化学工学会第54回秋季大会","化学工学会第54回秋季大会要旨集",,,,,2023,Aug. "Bo Zhu,Zhe Du,Yancen Dai,Tetsuya Kitaguchi,Sebastian Behrens,Burckhard Seelig","Nanodroplet-Based Reagent Delivery into Water-in-Fluorinated-Oil Droplets",,"Biosensors",,"Vol. 13",,"pp. 768",2023,July "Takanobu Yasuda,Tetsuya Kitaguchi","互いに引き合う螺旋状ペプチド : 二量体形成から細胞療法まで",,"月刊細胞","北隆館","Vol. 55","No. 9","pp. 749-753",2023,July "Takanobu Yasuda,大森 健太,Hiroshi Ueda,Tetsuya Kitaguchi","トラップ&リリースが拓いた免疫センサーの道と抗体薬物複合体の未来",,"生物工学会誌","公益社団法人 日本生物工学会","Vol. 101","No. 6","pp. 277-280",2023,June "Yoshihiro Ito,Ryuichi Sasaki,Sayaka Asari,Takanobu Yasuda,Hiroshi Ueda,Tetsuya Kitaguchi","Efficient Microfluidic Screening Method Using a Fluorescent Immunosensor for Recombinant Protein Secretions",,"Small",,"Volume 19","Issue 34"," 2207943",2023,Apr. "Akihito Inoue,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,村上明一,Hiroshi Ueda","酵母細胞表層提示系を用いたナノ抗体由来”nano Q-body”のTrp変異進化","化学工学会第88年会","化学工学会第88年会要旨集",,,,,2023,Mar. "Rianto Sato,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Naohiro Kato,Hiroshi Ueda","3分割ルシフェラーゼを用いた免疫測定法における相互作用の測定と数理モデルの作製","化学工学会第88年会","化学工学会第88年会要旨集",,,,,2023,Mar. "Yuri Osuga,Mai Takizawa,Rika Ishida,Marie Mita,Kazuki Harada,Tetsuya Kitaguchi,Takashi Tsuboi","Intracellular cGMP dynamics during incretin secretion revealed by red fluorescent protein-based cGMP sensor","第100回日本生理学会大会","第100回日本生理学会大会要旨集",,,,,2023,Mar. "Kazuki Harada,Maoko Takashima,Tetsuya Kitaguchi,Takashi Tsuboi","Temporal shift and involvement of actin in the docking dynamics of biphasic exocytosis of glucagon-like peptide-1.","第100回日本生理学会大会","第100回日本生理学会大会要旨集",,,,,2023,Mar. "Tetsuya Kitaguchi","Molecular evolution paves the way for development of fluorescent protein-based sensors.",,"第100回日本生理学会大会要旨集",,,,,2023,Mar. "Kazuki Harada,Maoko Takashima,Tetsuya Kitaguchi,Takashi Tsuboi","F-actin determines the time-dependent shift in docking dynamics of glucagon-like peptide-1 granules upon stimulation of secretion",,"FEBS lett",," 597",," 657",2023,Mar. "三田真理恵,坪井貴司,Tetsuya Kitaguchi","生体内のグルコース検出技術の進展と展望",,"月刊細胞",," 55",," 296-299",2023,Mar. "Abdul Qawee Rani,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","Recent progress in homogeneous immunosensors based on fluorescence or bioluminescence using antibody engineering",,"ANALYST",," 148",," 1422-1429",2023,Mar. "Donnell White III,Lothar Lauterboeck,Parnia Mobasheran,Tetsuya Kitaguchi,Antoine H. Chaanine,Qinglin Yang.","Real-time visualization of cytosolic and mitochondrial ATP dynamics in response to metabolic stress in cultured cells.",,"Cells",," 12",," 695",2023,Feb. "Bo Zhu,Cheng Qian,Haoxuan Tang,Tetsuya Kitaguchi,Hiroshi Ueda","Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces",,"Biochemistry",,,,,2023,Jan. "Tetsuya Kitaguchi","光るタンパク質が拓く細胞シグナルの世界",,"大隅ライフサイエンス研究会 第8回シンポジウム 要旨集",,,,,2022,Dec. "Tomoko Tsutsumi,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫センサーQuenchbodyのシグナル増幅と高速スクリーニング法の探索","第95回日本生化学会大会","第95回日本生化学会大会要旨集",,,,,2022,Nov. "B. Zhu,N. Nosaka,S. Kanamaru,J. Dong,Y. Dai,A. Inoue,Y. Yang,K. Kobayashi,T. Kitaguchi,H. Iwasaki,R. Koike,K. Wakabayashi,H. Ueda","Rapid and sensitive SARS-CoV-2 detection using a homogeneous fluorescent immunosensor Quenchbody with crowding agents",,"Analyst",,"Vol. 147","Number 22","p. 4971-4979",2022,Nov. "Cong Q. Vu,Taketoshi Kiya,Toshinori Fujie,Tetsuya Kitaguchi,Satoshi Arai","A green color fluorescence lifetime-based ATP biosensor","第45回日本分子生物学会年会","第45回日本分子生物学会年会要旨集",,,,,2022,Nov. "堀越美菜,角沙樹,Tetsuya Kitaguchi,原田一貴,松本光晴,坪井貴司","運動時の肝細胞における乳酸動態の可視化解析","第45回日本分子生物学会年会","第45回日本分子生物学会年会要旨集",,,,,2022,Nov. "角沙樹,堀越美菜,Tetsuya Kitaguchi,原田一貴,松本光晴,坪井貴司","肝臓における代謝機能の可視化解析","第45回日本分子生物学会年会","第45回日本分子生物学会年会要旨集",,,,,2022,Nov. "大須賀佑里,滝澤舞,石田りか,三田真理恵,原田一貴,Tetsuya Kitaguchi,坪井貴司","赤色cGMPセンサーを用いた消化管ホルモン分泌におけるcGMPの役割の解明","第45回日本分子生物学会年会","第45回日本分子生物学会年会要旨集",,,,,2022,Nov. "Keisuke Yamashita,Takashi Tsuboi,Hiroshi Ueda,Tetsuya Kitaguchi.","Development of a GFP-based biosensor for visualizing intracellular IP3 dynamics","第45回日本分子生物学会年会","第45回日本分子生物学会年会要旨集",,,,,2022,Nov. "Sohei Hiasa,Takeru Fujimori,Saki Aiki,Hiroshi Ueda,Takashi Tsuboi,Tetsuya Kitaguchi.","幅広い濃度範囲の検出を可能とする複数の緑色蛍光cAMPセンサーの開発","第45回日本分子生物学会年会","第45回日本分子生物学会年会要旨集",,,,,2022,Nov. "Kana Sasamoto,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","逆並行結合抑制型ペプチドペアによる抗体を蛍光免疫センサに変換するプローブタンパク質Coiled Q-probeの蛍光応答向上","第95回日本生化学会大会","第95回日本生化学会大会要旨集",,,,,2022,Nov. "Akihito Inoue,Takanobu Yasuda,Tetsuya Kitaguchi,村上明一,Hiroshi Ueda","酵母提示系によるナノ抗体由来の蛍光免疫センサnano Q-bodyの分子進化法の開発","第95回日本生化学会大会","第95回日本生化学会大会要旨集",,,,,2022,Nov. "Tetsuya Kitaguchi","分子進化と半合理デザインを駆使した遺伝子コード型蛍光センサーの創出",,"第96回日本薬理学会年会要旨集",,,,,2022,Nov. "Toshiaki Fukushima,Keijun Kakihara,Kengo Asamizu,森次 圭,Tetsuya Kitaguchi,Masayuki Komada","クッシング病を引き起こすUSP8の過剰活性化機構","第95回 日本生化学会大会シンポジウム「ユビキチンワールドを制御する脱ユビキチン化酵素の疾患、創薬における重要性」","第95回日本生化学会大会要旨集",,,,,2022,Nov. "Hiroshi Ueda,Jiulong Su,Bo Zhu,Akihito Inoue,大山浩之,森田いずみ,Jinhua Dong,小西良子,Tetsuya Kitaguchi,小林典裕,三宅司郎","各種食中毒から生活者を守る「パトロール酵母」の開発",,"第74回日本生物工学会大会要旨集",,,,,2022,Oct. "Hiroshi Ueda,Bo Zhu,Jiulong Su,Tetsuya Kitaguchi,Norihiro Kobayashi,Shiro Miyake.","Development of “patrol yeasts” for the detection of multiple toxic substances in foods","The 15th Asian Congress on Biotechnology","The 15th Asian Congress on Biotechnology",,,,,2022,Oct. "Ito Yoshihiro,佐々木隆一,朝里さやか,Tetsuya Kitaguchi,Hiroshi Ueda","微小ドロップレット培養とバイオセンサーを用いたタンパク質高生産株スクリーニング法の開発","第74回日本生物工学会大会","第74回日本生物工学会大会要旨集",,,,,2022,Oct. "Jiulong Su,Bo Zhu,Akihito Inoue,Hiroyuki Oyama,Izumi Morita,Jinhua Dong,Takanobu Yasuda,Yoshiko Sugita-Konishi,Tetsuya Kitaguchi,Norihiro Kobayashi,Shiro Miyake,Hiroshi Ueda","The Patrol Yeast: a new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning",,"Biosensors and Bioelectronics","Elsevier","Vol. 219",," 114793",2022,Oct. "Ito Yoshihiro,佐々木隆一,朝里さやか,Tetsuya Kitaguchi,Hiroshi Ueda","微小ドロップレット培養とバイオセンサーを用いたタンパク質高生産株スクリーニング法の開発",,"創立100周年記念 第74回日本生物工学会大会 トピックス集",,,," 22-23",2022,Oct. "Haruki Kurata,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","発光タグを付加したペプチドを用いた免疫センサーの構築","化学工学会第53回秋季大会","化学工学会第53 回秋季大会要旨集",,,,,2022,Sept. "Cong Quang Vu,Taketoshi Kiya,Toshinori Fujie,Tetsuya Kitaguchi,Satoshi Arai.","A green color fluorescence lifetime-based biosensor for quantitative imaging of intracellular ATP in multicellular system","第60回日本生物物理学会","第60回日本生物物理学会要旨集",,,,,2022,Sept. "Keijun Kakihara,Kei Moritsugu,Tetsuya Kitaguchi,Akinori Endo,Masayuki Komada,Toshiaki Fukushima","Autoinhibition of USP8 by WW-like domain and the dysregulation in Cushing’s disease","EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”","EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”",,,,,2022,Sept. "Fumiya Uefune,Toru Aonishi,Tetsuya Kitaguchi,Harumi Takahashi,Susumu Seino,Daisuke Sakano,Shoen Kume","Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer",,"Diabetes",,"Vol. 71","Issue 9","pp. 1946?1961",2022,Sept. "Takanobu Yasuda,Kana Sasamoto,Tetsuya Kitaguchi,Hiroshi Ueda","逆平行結合抑制ペプチドペアを用いたクエンチ抗体の構築と評価","第16回バイオ関連化学シンポジウム","第16回バイオ関連化学シンポジウム要旨集",,,,,2022,Sept. "Akihito Inoue,Taiga Suzuki,Yinghui Yang,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","コルチゾール認識ナノ抗体の蛍光免疫センサー化","第16回バイオ関連化学シンポジウム","第16回バイオ関連化学シンポジウム要旨集",,,,,2022,Sept. "Kazuki Harada,Maoko Takashima,Tetsuya Kitaguchi,Takashi Tsuboi.","Exocytotic dynamics of glucagon-like peptide-1 from enteroendocrine L cell line is regulated by actin polymerization",,"bioRxiv",,,,,2022,Sept. "Mai Takizawa,Yuri Osuga,Rika Ishida,Marie Mita,Kazuki Harada,Hiroshi Ueda,Tetsuya Kitaguchi,Takashi Tsuboi.","Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging.",,"Commun Biol",," 5",," 833",2022,Sept. "Bo Zhu,野坂 宜之,Jinhua Dong,Tetsuya Kitaguchi,小池 竜 司,若林 健二,Hiroshi Ueda","Converting antibodies to rapid response SARS-CoV-2 homogeneous immunosensors via Quenchbody technology and crowding agent","化学工学会第53回秋季大会","化学工学会第53 回秋季大会要旨集",,,,,2022,Sept. "Yancen Dai,Yuko Sato,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Kimura,Farid J. Ghadess,Hiroshi Ueda","Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting",,"Chemical Science","The Royal Society of Chemistry","Vol. 13","Issue 33","p. 9739-9748",2022,Aug. "Sohei Hiasa,Takeru Fujimori,Saki Aiki,Hiroshi Ueda,Takashi Tsuboi,Tetsuya Kitaguchi","Development of green fluorescent protein-based cAMP indicators with expanded dynamic range and various working ranges",,"Jxiv",,,,,2022,June "王軍鋒,辻村有紀,Tetsuya Kitaguchi,前田英次郎,横田秀夫,松本健郎","FRET型張力センサ発現マウスの血管と腱の引張に伴うFRET変化","日本機械学会 第34回バイオエンジニアリング講演会","日本機械学会 第34回バイオエンジニアリング講演会要旨集",,,,,2022,June "Ferdinandus,Madoka Suzuki,Yoshie Harada,Cong Quang Vu,Satya Ranjan Sarker,Shin’ichi Ishiwata,Tetsuya Kitaguchi,Satoshi Arai.","Modulation of Local Cellular Activities using a Photothermal Dye-Based Subcellular-Sized Heat Spot",,"ACS Nano",," 16",," 9004",2022,June "Dai Yancen,Sato Yuko,Zhu Bo,Kitaguchi Tetsuya,Kimura Hiroshi,Farid J. Ghadessy,Ueda Hiroshi","Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live-cell imaging and sorting","Bioanalytical Sensors Gordon Research Conference","Bioanalytical Sensors Gordon Research Conference",,,,,2022,June "Bo Zhu,Haimei Li,Yancen Dai,Akihito Inoue,Yinghui Yang,Kaori Kobayashi,Tetsuya Kitaguchi,Jinhua Dong,Hiroshi Ueda","Rapid construction of homogeneous immunosensors for SARS-CoV-2 nucleocapsid and spike proteins using Quenchbody and Quenchprobe technology","Bioanalytical Sensors Gordon Research Conference","Bioanalytical Sensors Gordon Research Conference",,,,,2022,June "Bo Zhu,Cheng Qian,Haoxuan Tang,Tetsuya Kitaguchi,Hiroshi Ueda.","Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces",,"bioRxiv",,,,,2022,May "Yancen Dai,Bo Zhu,Yuko Sato,Hiroshi Kimura,Farid J. Ghadessy,Tetsuya Kitaguchi,Hiroshi Ueda.","Development of an immunofluorescence probe Q-body for the direct visualization of tumor marker p53 in fixed and living cells.","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Yanmin Chen,Yancen Dai,Tetsuya Kitaguchi,Hiroshi Ueda.","Development of a multicolor Q-body construction method using Escherichia coli.","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Rika Tsubaki,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫センサーCoiled Quenchbodyのがん光線力学療法への応用","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Kaori Kobayashi,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫プローブQuenchprobeのダブルラベル化の検討","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Saki Tsuno,Marie Mita,Mina Horikoshi,Tetsuya Kitaguchi,Kazuki Harada Mitsuharu Matsumoto,Takashi Tsuboi.","In vivo imaging analysis of metabolic functions in the liver.","第99回日本生理学会大会","第99回日本生理学会大会要旨集",,,,,2022,Mar. "Mina Horikoshi,Saki Tsuno,Marie Mita,Tetsuya Kitaguchi,Kazuki Harada,Takashi Tsuboi.","Live-cell imaging analysis of glucose metabolism in hepatocytes.","第99回日本生理学会大会","第99回日本生理学会大会要旨集",,,,,2022,Mar. "Marie Mita,Izumi Sugawara,Kazuki Harada,Motoki Ito,Mai Takizawa,Kentaro Ishida,Hiroshi Ueda,Tetsuya Kitaguchi,Takashi Tsuboi.","Visualization of intracellular glucose metabolism dynamics by red fluorescent protein-based glucose indicators.","第99回日本生理学会大会","第99回日本生理学会大会要旨集",,,,,2022,Mar. "Kazuki Harada,Maoko Takahsima,Tetsuya Kitaguchi,Takashi Tsuboi.","Involvement of intracellular second messengers and cytoskeleton in the exocytosis of intestinal hormone.","第99回日本生理学会大会","第99回日本生理学会大会要旨集",,,,,2022,Mar. "Marie Mita,Izumi Sugawara,Kazuki Harada,Motoki Ito,Mai Takizawa,Kentaro Ishida,Hiroshi Ueda,Tetsuya Kitaguchi,Takashi Tsuboi.","Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics",,"Cell Chem Biol",," 29",," 98",2022,Jan. "Keijun Kakihara,Kengo Asamizu,森次圭,Tetsuya Kitaguchi,Akinori Endo,木寺詔記,池口満徳,Masayuki Komada,Toshiaki Fukushima","脱ユビキチン化酵素USP8の自己阻害機構とクッシング病関連変異によるその解除","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Takanobu Yasuda,Yoshiyuki Ueno,栃尾尚哉,八木宏昌,Tetsuya Kitaguchi,Takanori Kigawa,Hiroshi Ueda","NMRによる新規免疫センサーHibodyの抗原結合に伴う発光活性増大機構の解明","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "三田真理恵,菅原和,原田一貴,伊藤幹,滝澤舞,石田賢太郎,Hiroshi Ueda,Tetsuya Kitaguchi,坪井貴司","赤色蛍光タンパク質型グルコースセンサーの開発と糖代謝のライブセルイメージング","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Mai Honjo,Hiroshi Aihara,Yanyan Hou,Hiroshi Ueda,伊藤寿朗,Tetsuya Kitaguchi","抗体を分子認識ドメインとする蛍光タンパク質プローブを用いたジベレリンの定量","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Keisuke Yamashita,Ippei Tsujimura,Takashi Tsuboi,Hiroshi Ueda,Tetsuya Kitaguchi.","Generation of a genetically-encoded IP3 biosensor based on a green fluorescent protein.","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Sohei Hiasa,Takeru Fujimori,Saki Aiki,Hiroshi Ueda,Takashi Tsuboi,Tetsuya Kitaguchi.","Development of green fluorescent protein-based indicators visualizing wide-range of cAMP dynamics for live-cell imaging.","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Kazuki Harada,Maoko Takahsima,Tetsuya Kitaguchi,Takashi Tsuboi.","Role of intracellular Ca2+ and cAMP in glucagon-like peptide-1 exocytosis from enteroendocrine L cells.","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Ippei Tsujimura,Hiroshi Ueda,Tetsuya Kitaguchi.","Development of an antibody-based red fluorescent probe and its characterization.","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Junfeng Wang,Yuki Tsujimura,Tetsuya Kitaguchi,Eijiro Maeda,Hideo Yokota,Takeo Matsumoto.","Generation and evaluation of transgenic mice expressing tension sensor based on FRET.","The 11th Asian-Pacific Conference on Biomechanics","The 11th Asian-Pacific Conference on Biomechanics",,,,,2021,Dec. "原田一貴,Tetsuya Kitaguchi,坪井貴司","蛍光タンパク質を用いた緑色乳酸センサーとピルビン酸センサーの開発",,"比較内分泌学",," 47",," e0007",2021,Dec. "Ferdinandus,Madoka Suzuki,Yoshie Harada,Satya Ranjan Sarker,Shin’ichi Ishiwata,Tetsuya Kitaguchi,Satoshi Arai.","Photothermal dye-based subcellular-sized heat spot enabling the modulation of local cellular activities.",,"bioRxiv",,,,,2021,Dec. "Akihito Inoue,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Akikazu Murakami,Hiroshi Ueda","Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface",,"Scientific Reports","Springer Nature","Vol. 11",,"p. 22590",2021,Nov. "Akihito Inoue,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Akikazu Murakami,Hiroshi Ueda.","Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface.",,"Res Sq",,,,,2021,Nov. "Takanobu Yasuda,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda","レシオ計測が可能な蛍光免疫センサーFRET Coiled Q-bodyにおけるDonor-Acceptor間距離の検討","第94回日本生化学会大会","第94回日本生化学会大会要旨集",,,,,2021,Nov. "Takanobu Yasuda,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫センサープローブCoiled Q-probeを用いた各種低分子の検出と,FRET型プローブへの展開","第94回日本生化学会大会","第94回日本生化学会大会要旨集",,,,,2021,Nov. "Kaito Iijima,Yoshiyuki Ueno,Tetsuya Kitaguchi,Hiroshi Ueda","発光タグ融合抗体結合タンパク質を用いた新規抗原検出系の構築","第94回日本生化学会大会","第94回日本生化学会大会要旨集",,,,,2021,Nov. "Keijun Kakihara,Kengo Asamizu,Kei Moritsugu,Masahide Kubo,Tetsuya Kitaguchi,Akinori Endo,Akinori Kidera,Mitsunori Ikeguchi,Akira Kato,Masayuki Komada,Toshiaki Fukushima.","Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.",,"Commun Biol",," 4",," 1272",2021,Nov. "Yancen Dai,Atsushi Izutani,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","Intracellular detection of tumor suppressor protein p53 by Q-body technology","第 73回日本生物工学会大会","第 73回日本生物工学会大会要旨集",,,,,2021,Oct. "Akihito Inoue,Takanobu Yasuda,Tetsuya Kitaguchi,村上 明一,Hiroshi Ueda","酵母提示系を用いたナノ抗体由来の蛍光免疫センサ“mini Q-body”選択法の開発","第 73回日本生物工学会大会","第 73回日本生物工学会大会要旨集",,,,,2021,Oct. "王軍鋒,辻村 有紀,Tetsuya Kitaguchi,前田 英次郎,横田 秀夫,松本健郎","FRET型張力センサを発現するトランスジェニックマウスの作製と評価","日本機械学会 2021年度年次大会",,,,,,2021,Sept. "Akihito Inoue,Yuki Ohmuro,Tetsuya Kitaguchi,Hiroshi Ueda","Construction of mini Q-body using the nanobody to detect chemotherapy agent.","Nonobodies (Hybrid 2nd edition)",,,,,,2021,Sept. "Junetae Park,Ryota Arisaka,柴田貴広,内田浩二,Jinhua Dong,Tetsuya Kitaguchi,Hiroshi Ueda","ゲノム編集法によるオープンサンドイッチ免疫測定用抗体の産生","化学工学会第52回秋季大会","化学工学会第52回秋季大会要旨集",,,,,2021,Sept. "Akihito Inoue,Takanobu Yasuda,Tetsuya Kitaguchi,村上 明一,Hiroshi Ueda","酵母細胞表層提示系を用いた抗ヒト血清アルブミン (HSA)ナノ抗体由来“mini Q-body”の選択","化学工学会第52回秋季大会","化学工学会第52回秋季大会要旨集",,,,,2021,Sept. "Bo Zhu,Jinhua Dong,寧雪じょう,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda","Quenchbodyを用いた1分間SARS-CoV-2及び変異株の検出法","化学工学会第52回秋季大会","化学工学会第52回秋季大会要旨集",,,,,2021,Sept. "Akihito Inoue,Yuki Ohmuro,Tetsuya Kitaguchi,Hiroshi Ueda","Construction of mini Q-body using the nanobody to detect chemotherapy agent.","31st Anniversary World Congress on Biosensors",,,,,,2021,July "Hiroshi Ueda,Jinhua Dong,Takanobu Yasuda,Masaki Takahashi,Kana Sasamoto,Hiroyuki Oyama,Izumi Morita,Hee-Jin Jeong,Tetsuya Kitaguchi,Norihiro Kobayashi.","PM Q-probe: a fluorescent binding protein that converts many antibodies to a fluorescent biosensor.","31st Anniversary World Congress on Biosensors",,,,,,2021,July "Xuerao Ning,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","Construction of Fluorescent Immunosensor Quenchbody to Detect His-Tagged Recombinant Proteins Produced in Bioprocess",,"Sensors","MDPI","vol. 21","Issue 15","p. 4993",2021,July "T. Yasuda,A. Inoue,T. Kitaguchi,H. Ueda","Rapid construction of fluorescence quenching-based immunosensor Q-bodies using α-helical coiled-coil peptides",,"Chemical Communications",,"vol. 57",,"p. 8206-8209",2021,July "新井敏,サルケア・サティア,Tetsuya Kitaguchi","単色蛍光タンパク質型FLIMセンサーを用いたATPの時空間定量イメージング","第21回日本蛋白質科学会年会","第21回日本蛋白質科学会年会要旨集",,,,,2021,June "Hiroshi Ueda,Ryota Arisaka,朴俊泰,Jinhua Dong,柴田貴広,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,内田浩二","ゲノム編集法による酸化脂質類の非競合的免疫測定系の構築","第74回日本酸化ストレス学会・第21回日本NO学会 合同学術集会","第74回日本酸化ストレス学会・第21回日本NO学会 合同学術集会要旨集",,,,,2021,May "Tetsuya Kitaguchi","蛍光タンパク質センサーの革新を目指すマルチカラー化と分子認識能の多様化","3大学医工連携オンラインセミナー","3大学医工連携オンラインセミナー・Web要旨集",,,,,2021,May "Marie Mita,Devina Wongso,Hiroshi Ueda,Takashi Tsuboi,Tetsuya Kitaguchi","Development of a single fluorescent protein-based green glucose indicator by semirational molecular design and molecular evolution.",,"Methods Mol Biol","Springer"," 2274",," 89-100",2021,May "Keijun Kakihara,Kengo Asamizu,Kei Moritsugu,Masahide Kubo,Tetsuya Kitaguchi,Akinori Endo,Akinori Kidera,Mitsunori Ikeguchi,Akira Kato,Masayuki Komada,Toshiaki Fukushima","The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain",,"bioRxiv",,,,,2021,May "Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Kimura,Hiroshi Ueda","Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies",,"ACS Omega","American Chemical Society","vol. 6","Issue 15","p. 10039-10046",2021,Apr. "Xuerao Ning,Tetsuya Kitaguchi,Hiroshi Ueda","Construction of fluorescent biosensor Q-body for detecting recombinant proteins produced in bioprocess","化学工学会第86年会","化学工学会第86年会要旨集",,,,,2021,Mar. "Kana Sasamoto,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","迅速簡便に高性能な蛍光免疫センサーを構築可能なCoiled Q-probeの創出","化学工学会第86年会","化学工学会第86年会要旨集",,,,,2021,Mar. "Junqian Wang,Tetsuya Kitaguchi,Hiroshi Ueda","Development of a novel immunosensor system based on antigen-dependent assembly of fluorescent proteins.","化学工学会第86年会","化学工学会第86年会要旨集",,,,,2021,Mar. "Yancen Dai,Atsushi Izutani,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda.","Instant detection of tumor suppressor protein p53 by Q-body technology.","化学工学会第86年会","化学工学会第86年会要旨集",,,,,2021,Mar. "Zhu Bo,Dong Jinhua,Xuerao Ning,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda.","Development of quenchbody-based 1-minute SARS-CoV-2 detection assay.","化学工学会第86年会","化学工学会第86年会要旨集",,,,,2021,Mar. "Kazuki Harada,Takumi Nakamura,Taichi Kamiya,Mai Takizawa,Kazuo Nakajima,Tetsuya Kitaguchi,Kunihiro Ohta,Tadafumi Kato,Takashi Tsuboi.","Mechanism of L-glutamine-induced glucagon-like peptide-1 secretion via taste receptor and cAMP signaling.","第98回日本生理学会大会","第98回日本生理学会大会要旨集",,,,,2021,Mar. "Marie Mita,Mai Takizawa,Rei Nagata,Kazuki Harada,Hiroshi Ueda,Tetsuya Kitaguchi,Takashi Tsuboi.","Sucralose activates intracellular Ca2+ and cAMP signaling in enteroendocrine L cells.","第98回日本生理学会大会","第98回日本生理学会大会要旨集",,,,,2021,Mar. "Hiroshi Aihara,Yanyan Hou,Hiroshi Ueda,Toshiro Ito,Tetsuya Kitaguchi.","Development of a plant hormone probe employing antibody as molecular recognition domain for visualizing intracellular dynamics.","第43回日本分子生物学会年会","第43回日本分子生物学会年会要旨集",,,,,2020,Dec. "Takeru Fujimori,Saki Aiki,Hiroshi Ueda,Takashi Tsuboi,Tetsuya Kitaguchi.","Development of turn-on type green fluorescent cAMP biosensors applicable to wide range of cAMP dynamics.","第43回日本分子生物学会年会","第43回日本分子生物学会年会要旨集",,,,,2020,Dec. "Jiulong Su,Tetsuya Kitaguchi,Norihiro Kobayashi,Shiro Miyake,Hiroshi Ueda.","Development of patrol yeasts for the detection of toxic substances in foods.","第43回日本分子生物学会年会","第43回日本分子生物学会年会要旨集",,,,,2020,Dec. "Ippei Tsujimura,Hiroshi Aihara,Hiroshi Ueda,Tetsuya Kitaguchi.","Development of a red fluorescent probe inducing its intensity change by antigen binding.","第43回日本分子生物学会年会","第43回日本分子生物学会年会要旨集",,,,,2020,Dec. "Akihito Inoue,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Ueda","Creation of a Nanobody-Based Fluorescent Immunosensor Mini Q‐body for Rapid Signal-On Detection of Small Hapten Methotrexate",,"ACS Sensors",,"vol. 5","no. 11","p. 3457?3464",2020,Nov. "Kazuki Harada,Takami Chihara,Yuki Hayasaka,Marie Mita,Mai Takizawa,Kentaro Ishida,Mary Arai,Saki Tsuno,Mitsuharu Matsumoto,Takeshi Ishihara,Hiroshi Ueda,Tetsuya Kitaguchi,Takashi Tsuboi","Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.",,"Sci Rep",," 10",," 19562",2020,Nov. "Akihito Inoue,Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫センサーQ-bodyを提示した酵母細胞の構築と抗原検出","化学工学会第51回秋季大会","化学工学会第51回秋季大会要旨集",,,,,2020,Sept. "Hiroshi Ueda,Jinhua Dong,Chihiro Miyake,Takanobu Yasuda,Masaki Takahashi,大山浩之,森田いずみ,Tetsuya Kitaguchi,小林典裕","抗体を蛍光免疫センサーQ-body 化可能なタンパク質PM Q-probe による各種バイオマーカーの測定","化学工学会第51回秋季大会","化学工学会第51回秋季大会要旨集",,,,,2020,Sept. "Jiulong Su,Yasuyuki Nakamura,Tetsuya Kitaguchi,Jun Ishii,Akihito Kondo,Norihiro Kobayashi,Shiro Miyake,Hiroshi Ueda.","Development of patrol yeasts for the detection of toxic substances in foods.","第93回日本生化学会大会","第93回日本生化学会大会要旨集",,,,,2020,Sept. "J. Dong,C. Miyake,T. Yasuda,H. Oyama,I. Morita,T. Tsukahara,M. Takahashi,H.-J. Jeong,T. Kitaguchi,N. Kobayashi,H. Ueda","PM Q-probe: A fluorescent binding protein that converts many antibodies to a fluorescent biosensor",,"Biosensors and Bioelectronics","Elsevier","vol. 165",,"p. 112425",2020,July "Takanobu Yasuda,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda.","Creation and evaluation of immunosensors that enable ratiometric assay by rapid dual-color labeling of antibody fragments.","第20回日本蛋白質科学会年会","第20回日本蛋白質科学会年会要旨集",,,,,2020,July "Yoshiyuki Ueno,Naoya Tochio,Junqian Wang,Tetsuya Kitaguchi,Takanori Kigawa,Hiroshi Ueda.","Mechanistic analysis of novel immunosensor Hibody to clarify the antigen-dependent protrusion of tag sequence attached to the antibody N-terminus.","第20回日本蛋白質科学会年会","第20回日本蛋白質科学会年会要旨集",,,,,2020,July "Tetsuya Kitaguchi","細胞生理機能を操る!人工の受容体から臨床応用まで",,"生物工学会誌",," 98",," 194",2020,Apr. "Chungyong Han,Beom K. Choi,Seon-Hee Kim,Su-Jung Sim,Seongeun Han,Bomi Park,Yohei Tsuchiya,Masaki Takahashi,Young H. Kim,Hyeon-Seok Eom,Tetsuya Kitaguchi,Hiroshi Ueda,Byoung S. Kwon","Polymorphic region-specific antibody for evaluation of affinity-associated profile of chimeric antigen receptor",,"Molecular Therapy: Oncolytics","Cell Press","Vol. 17",,"p. 293-305",2020,Apr. "Takumi Nakamura,Kazuki Harada,Taichi Kamiya,Mai Takizawa,Jim K?ppers,Kazuo Nakajima,Michael G?tschow,Tetsuya Kitaguchi,Kunihiro Ohta,Tadafumi Kato,Takashi Tsuboi.","Glutamine-induced signaling pathways via amino acid receptors in enteroendocrine L cell lines.",,"J Mol Endocrinol",," 64",," 133-143",2020,Apr. "Ryota Arisaka,Tetsuya Kitaguchi,Hiroshi Ueda","ハイブリドーマ細胞のゲノム編集によるオープンサンドイッチ免疫測定用人工抗体の生産","化学工学会第85年会","化学工学会第85年会要旨集",,,,,2020,Mar. "Kanai, Y.,Ohmuro-Matsuyama, Y.,Tanioku, M.,Ushiba, S.,Ono, T.,Inoue, K.,Kitaguchi, T.,Kimura, M.,Ueda, H.,Matsumoto, K.","Graphene Field Effect Transistor-Based Immunosensor for Ultrasensitive Noncompetitive Detection of Small Antigens",,"ACS Sensors",,"Vol. 5","No. 1","p. 24-28",2020,Jan. "Yuki Oe,Xiaowen Wang,Tommaso Patriarchi,Ayumu Konno,Katsuya Ozawa,Kazuko Yahagi,Hirokazu Hirai,Takashi Tsuboi,Tetsuya Kitaguchi,Lin Tian,Thomas J McHugh,Hajime Hirase.","Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance.",,"Nat Commun",," 11",," 471",2020,Jan. "高橋昌樹,Jinhua Dong,Tetsuya Kitaguchi,Hiroshi Ueda","抗体結合タンパク質Mからなる蛍光バイオセンサープローブ"Q-probe"の熱安定化と各種抗原検出への応用","第42回日本分子生物学会年会","第42回日本分子生物学会年会要旨集",,,,,2019,Dec. "Kazuki Harada,Takumi Nakamura,Taichi Kamiya,Mai Takizawa,Kazuo Nakajima,Tetsuya Kitaguchi,Kunihiro Ohta,Tadafumi Kato,Takashi Tsuboi.","Mechanism of L-glutamine-induced glucagon-like peptide-1 secretion from enteroendocrine L cells via amino acid receptors.","第42回日本分子生物学会年会","第42回日本分子生物学会年会要旨集",,,,,2019,Dec. "Hiroshi Aihara,Yanyan Hou,Hiroshi Ueda,伊藤寿朗,Tetsuya Kitaguchi","生細胞イメージングを目指した遺伝子コード型ジベレリンプローブの開発","第42回日本分子生物学会年会","第42回日本分子生物学会年会要旨集",,,,,2019,Dec. "千原貴美,三田真理恵,菅原和,相木彩希,早坂優希,原田一貴,Hiroshi Ueda,Tetsuya Kitaguchi,坪井貴司","蛍光タンパク質を用いた緑色蛍光輝度変化型乳酸センサーの開発","第42回日本分子生物学会年会","第42回日本分子生物学会年会要旨集",,,,,2019,Dec. "三田真理恵,伊藤幹,原田一貴,菅原和,永田怜,芦田翼,Hiroshi Ueda,坪井貴司,Tetsuya Kitaguchi","緑色蛍光グルコースセンサーが検出する人工甘味料による膵β細胞のグルコース恒常性攪乱","第42回日本分子生物学会年会","第42回日本分子生物学会年会要旨集",,,,,2019,Dec. "Jiulong Su,Tetsuya Kitaguchi,Yuki Ohmuro-Matsuyama,Theresa Seah,Farid J. Ghadessy,Shawn Hoon,Hiroshi Ueda","Transmembrane signaling on a protocell: Creation of receptor-enzyme chimeras for immunodetection of specific antibodies and antigens",,"Scientific Reports","Springer-Nature","vol. 9",,"p. 18189",2019,Dec. "Chihiro Adachi,Naoto Kakinuma,Soohyun Jo,Takayuki Ishii,Yusuke Arai,Satoshi Arai,Tetsuya Kitaguchi,Sen Takeda,Takafumi Inoue.","Sonic hedgehog enhances calcium oscillations in hippocampal astrocytes.",,"J Biol Chem",," 294",," 16034-16048",2019,Nov. "Kaoru Uesugi,Yuki Mori,Johannes Nicolaus Wibisana,Tetsuya Kitaguchi,Osamu Tabata,Keisuke Morishima.","Design of microstructure for developing fret function induced cell based force sensor.","?TAS 2019",,,,,,2019,Oct. "Cyrus Beh,Theresa Seah,Jiulong Su,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Ueda,Shawn Hoon.","Facile method for creating arrays of lipid-capped elastomer microwells for bioinspired protocellular sensors.","?TAS 2019",,,,,,2019,Oct. "Jiulong Su,Cyrus Beh,Tetsuya Kitaguchi,Yuki Ohmuro,Theresa Seah,Shawn Hoon,Hiroshi Ueda.","Creation of a novel sensor enzyme and its integration into protocell for digital detection of various anti-epitope tag antibodies.","18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019)",,,,,,2019,Sept. "Hiroshi Ueda,Takanobu Yasuda,Yoshiyuki Ueno,Akihito Inoue,Masaki Takahashi,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Jinhua Dong","Beyond Q-body: 色素修飾が不要な新規免疫測定素子の構築","第 71回日本生物工学会大会","第 71回日本生物工学会大会要旨集",,,,,2019,Sept. "上杉薫,ウィビサナ・ジョハネス ニコラウス,Tetsuya Kitaguchi,田畑修,森島圭祐","細胞利用型力センサの開発を目的とした細胞へのFRET機能遺伝子導入","第37回日本ロボット学会学術講演会","第37回日本ロボット学会学術講演会要旨集",,,,,2019,Sept. "Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Kimura,Hiroshi Ueda","YFP断片融合抗体プローブを用いたヒストン翻訳後修飾検出系の構築","第 71回日本生物工学会大会","第 71回日本生物工学会大会要旨集",,,,,2019,Sept. "Junfeng Wang,Shukei Sugita,Tatsuo Michiue,Takashi Tsuboi,Tetsuya Kitaguchi,Takeo Matsumoto.","A novel FRET analysis method for a single actin stress fiber: Application to MC3T3-E1 cells during movement on a substrate.",,"J Biorheol",," 33",," 21-26",2019,July "Akihito Inoue,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Ueda","ナノ抗体を用いた抗がん剤センサーmini Q-body の構築","第19回日本蛋白質科学会年会","第19回日本蛋白質科学会年会要旨集",,,,,2019,June "Yoshiyuki Ueno,Takanobu Yasuda,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Ueda","N末にNanoluc由来タグを持つ抗体断片は抗原依存的にNanolucの発光活性を増大させる","第19回日本蛋白質科学会年会","第19回日本蛋白質科学会年会要旨集",,,,,2019,June "Takanobu Yasuda,Tetsuya Kitaguchi,Hiroshi Ueda","コイルドコイル形成ペプチドを利用した蛍光ラベル化法による抗体断片の迅速FRETバイオセンサー化","第19回日本蛋白質科学会年会","第19回日本蛋白質科学会年会要旨集",,,,,2019,June "Jiulong Su,Cyrus Beh,Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Shawn Hoon,Hiroshi Ueda","Creation of stable and strictly regulated enzyme switch for signal-on immunodetection of various small antigens",,"Journal of Bioscience and Bioengineering",,,,,2019,June "Yuki Ohmuro-Matsuyama,Tetsuya Kitaguchi,Hiroshi Kimura,Hiroshi Ueda","分割YFP融合Intrabodyを用いた生細胞内ヒストンアセチル化検出プローブの構築","第19回日本蛋白質科学会年会","第19回日本蛋白質科学会年会要旨集",,,,,2019,June "新井敏,Tetsuya Kitaguchi","細胞内ATPの同時計測を可能にする3色の蛍光センサー",,"B&I",," 77"," 22"," 130-131",2019,Mar. "M. Mita,M. Ito,I. Sugawara,H. Ueda,T. Tsuboi,T. Kitaguchi","Green fluorescent protein-based glucose indicators report glucose dynamics in living cells",,"Analytical Chemistry",,"Vol. 91","No. 7","p. 4821-4830",2019,Mar. "Hiroshi Ueda,Yuki Omuro,Tetsuya Kitaguchi","均相系測定を可能にする抗原応答性標識抗体の創製","日本分析化学会第67年会",,,,,,2018,Sept. "Satoshi Arai,R?kus Kriszt,Kazuki Harada,Liang-Sheng Looi,Shogo Matsuda,Devina Wongso,Satoshi Suo,Shoichi Ishiura,Yu-Hua Tseng,Michael Raghunath,Toshiro Ito,Takashi Tsuboi,Tetsuya Kitaguchi.","RGB-color intensiometric indicators visualize spatiotemporal dynamics of ATP in single cells.",,,,,,,2018,Aug. "Jiulong Su,Jinhua Dong,Tetsuya Kitaguchi,Yuki Omuro,Hiroshi Ueda","Noncompetitive homogeneous immunodetection of small molecules based on beta-glucuronidase complementation",,"Analyst",,"vol. 143",,"p. 2096-2101",2018,Apr. "Hiroshi Ueda,Chihiro Miyake,Tomoya Tsukahara,高橋昌樹,児島智樹,Heejin Jeong,Jinhua Dong,Tetsuya Kitaguchi,大橋広之","蛍光免疫センサーQ-body迅速構築のための新しい戦略","化学工学会第49回秋季大会","化学工学会第49回秋季大会要旨集",,,,,2017,Sept. "Harada, Kazuki,Ito, Motoki,Wang, Xiaowen,Tanaka, Mika,Wongso, Devina,Konno, Ayumu,Hirai, Hirokazu,Hirase, Hajime,Tsuboi, Takashi,Tetsuya Kitaguchi","Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging",,"Scientific Reports",,"Vol. 7",,,2017,Aug. "Harada, Kazuki,Tetsuya Kitaguchi,Kamiya, Taichi,Aung, Kyaw Htet,Nakamura, Kazuaki,Ohta, Kunihiro,Tsuboi, Takashi","Lysophosphatidylinositol-induced activation of the cation channel TRPV2 triggers glucagon-like peptide-1 secretion in enteroendocrine L cells",,"Journal of Biological Chemistry",,"Vol. 292","No. 26","pp. 10855-10864",2017,June "Devina Wongso,Jinhua Dong,Hiroshi Ueda,Tetsuya Kitaguchi","Flashbody: a next generation Fluobody with fluorescence intensity enhanced by antigen binding",,"Analytical Chemistry",,"Vol. 89",,"p. 6719-6725",2017,May "Hou, Yanyan,Tetsuya Kitaguchi,Kriszt, Rokus,Tseng, Yu-Hua,Raghunath, Michael,Suzuki, Madoka","Ca2+- associated triphasic pH changes in mitochondria during brown adipocyte activation",,"Molecular Metabolism",,"Vol. 6","No. 8","pp. 797-808",2017,May "Kriszt, Rokus,Arai, Satoshi,Itoh, Hideki,Lee, Michelle H.,Goralczyk, Anna G.,Ang, Xiu Min,Cypess, Aaron M.,White, Andrew P.,Shamsi, Farnaz,Xue, Ruidan,Lee, Jung Yeol,Lee, Sung-Chan,Hou, Yanyan,Tetsuya Kitaguchi,Sudhaharan, Thankiah,Ishiwata, Shin'ichi,Lane, E. Birgitte,Chang, Young-Tae,Tseng, Yu-Hua,Suzuki, Madoka,Raghunath, Michael","Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes",,"Scientific Reports",,"Vol. 7",,,2017,May "Matsuda, Shogo,Harada, Kazuki,Ito, Motoki,Takizawa, Mai,Wongso, Devina,Tsuboi, Takashi,Tetsuya Kitaguchi","Generation of a cGMP Indicator with an Expanded Dynamic Range by Optimization of Amino Acid Linkers between a Fluorescent Protein and PDE5 alpha",,"Acs Sensors",,"Vol. 2","No. 1","pp. 46-51",2017,Jan. "Medina, Johan,Nakagawa, Yuko,Nagasawa, Masahiro,Fernandez, Anny,Sakaguchi, Kazushige,Tetsuya Kitaguchi,Kojima, Itaru","Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose",,"Journal of Biological Chemistry",,"Vol. 291","No. 44","pp. 23126-23135",2016, "Junfeng Wang,Masahiro Ito,Wenhao Zhong,Shukei Sugita,Tatsuo Michiue,Takashi Tsuboi,Tetsuya Kitaguchi,Takeo Matsumoto.","Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor.",,"J Biomech Sci Eng",,"Vol. 11","No. 4"," 16-00504",2016, "Hou, Yanyan,Arai, Satoshi,Tetsuya Kitaguchi,Suzuki, Madoka","Intracellular bottom-up generation of targeted nanosensors for single-molecule imaging",,"Nanoscale",,"Vol. 8","No. 6","pp. 3218-3225",2016, "Yamashita, Satoshi,Tsuboi, Takashi,Ishinabe, Nanako,Tetsuya Kitaguchi,Michiue, Tatsuo","Wide and high resolution tension measurement using FRET in embryo",,"Scientific Reports",,"Vol. 6",,,2016, "Harada, Kazuki,Tetsuya Kitaguchi,Tsuboi, Takashi","Integrative function of adrenaline receptors for glucagon-like peptide-1 exocytosis in enteroendocrine L cell line GLUTag",,"Biochemical and Biophysical Research Communications",,"Vol. 460","No. 4","pp. 1053-1058",2015, "Oya, Manami,Tetsuya Kitaguchi,Harada, Kazuki,Numano, Rika,Sato, Takahiro,Kojima, Masayasu,Tsuboi, Takashi","Low glucose-induced ghrelin secretion is mediated by an ATP-sensitive potassium channel",,"Journal of Endocrinology",,"Vol. 226","No. 1","pp. 25-34",2015, "Odaka, Haruki,Arai, Satoshi,Inoue, Takafumi,Tetsuya Kitaguchi","Genetically-Encoded Yellow Fluorescent cAMP Indicator with an Expanded Dynamic Range for Dual-Color Imaging",,"Plos One",,"Vol. 9","No. 6",,2014, "Tetsuya Kitaguchi,Oya, Manami,Wada, Yoshiko,Tsuboi, Takashi,Miyawaki, Atsushi","Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells",,"Biochemical Journal",,"Vol. 450",,"pp. 365-373",2013, "Oya, Manami,Tetsuya Kitaguchi,Pais, Ramona,Reimann, Frank,Gribble, Fiona,Tsuboi, Takashi","The G Protein-coupled Receptor Family C Group 6 Subtype A (GPRC6A) Receptor Is Involved in Amino Acid-induced Glucagon-like Peptide-1 Secretion from GLUTag Cells",,"Journal of Biological Chemistry",,"Vol. 288","No. 7","pp. 4513-4521",2013, "Oya, Manami,Tetsuya Kitaguchi,Yanagihara, Yu,Numano, Rika,Kakeyama, Masaki,Ikematsu, Kazuya,Tsuboi, Takashi","Vesicular nucleotide transporter is involved in ATP storage of secretory lysosomes in astrocytes",,"Biochemical and Biophysical Research Communications",,"Vol. 438","No. 1","pp. 145-151",2013, "Shimozono, Satoshi,Iimura, Tadahiro,Kitaguchi, Tetsuya,Higashijima, Shin-ichi,Miyawaki, Atsushi,Tetsuya Kitaguchi","Visualization of an endogenous retinoic acid gradient across embryonic development",,"Nature",,"Vol. 496","No. 7445","pp. 363-+",2013, "Sato, Mai,Kitaguchi, Tetsuya,Numano, Rika,Ikematsu, Kazuya,Kakeyama, Masaki,Murata, Masayuki,Sato, Ken,Tsuboi, Takashi,Tetsuya Kitaguchi","The small GTPase Cdc42 modulates the number of exocytosis-competent dense-core vesicles in PC12 cells",,"Biochemical and Biophysical Research Communications",,"Vol. 420","No. 2","pp. 417-421",2012, "Mori, Ryoichi,Ikematsu, Kazuya,Kitaguchi, Tetsuya,Kim, Sang E.,Okamoto, Momoko,Chiba, Takuya,Miyawaki, Atsushi,Shimokawa, Isao,Tsuboi, Takashi,Tetsuya Kitaguchi","Release of TNF-alpha from macrophages is mediated by small GTPase Rab37",,"European Journal of Immunology",,"Vol. 41","No. 11","pp. 3230-3239",2011, "Tsuboi, Takashi,Kitaguchi, Tetsuya,Karasawa, Satoshi,Fukuda, Mitsunori,Miyawaki, Atsushi,Tetsuya Kitaguchi","Age-dependent Preferential Dense-Core Vesicle Exocytosis in Neuroendocrine Cells Revealed by Newly Developed Monomeric Fluorescent Timer Protein",,"Molecular Biology of the Cell",,"Vol. 21","No. 1","pp. 87-94",2010, "Aoki, Ryo,Kitaguchi, Tetsuya,Miyawaki, Atsushi,Tsuboi, Takashi,Tetsuya Kitaguchi","Myosin II modulates fusion pore opening period via cortical F-actin reorganization",,"Journal of Physiological Sciences",,"Vol. 60",,"pp. S176",2010, "Aoki, Ryo,Kitaguchi, Tetsuya,Oya, Manami,Yanagihara, Yu,Sato, Mai,Miyawaki, Atsushi,Tsuboi, Takashi,Tetsuya Kitaguchi","Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis",,"Biochemical Journal",,"Vol. 429",,"pp. 497-504",2010, "Tsuboi, Takashi,Kitaguchi, Tetsuya,Karasawa, Satoshi,Fukuda, Mitsunori,Miyawaki, Atsushi,Tetsuya Kitaguchi","Age-dependent preferential secretory vesicle exocytosis in neuroendocrine cells",,"Journal of Physiological Sciences",,"Vol. 60",,"pp. S11",2010, "Aoki, Ryo,Kitaguchi, Tetsuya,Tsuboi, Takashi,Tetsuya Kitaguchi","MYOSIN II REGULATES "KISS-AND-RUN" DENSE-CORE EXOCYTOSIS REVEALED BY TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY",,"Journal of Physiological Sciences",,"Vol. 59",,"pp. 301",2009, "Sugiyama, Mayu,Sakaue-Sawano, Asako,Iimura, Tadahiro,Fukami, Kiyoko,Kitaguchi, Tetsuya,Kawakami, Koichi,Okamoto, Hitoshi,Higashijima, Shin-ichi,Miyawaki, Atsushi,Tetsuya Kitaguchi","Illuminating cell-cycle progression in the developing zebrafish embryo",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 106","No. 49","pp. 20812-20817",2009, "Kitaguchi, Tetsuya,Kawakami, Koichi,Kawahara, Atsuo,Tetsuya Kitaguchi","Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesis",,"Mechanisms of Development",,"Vol. 126","No. 5-6","pp. 314-323",2009, "Futatsugi, A,Nakamura, T,Yamada, MK,Ebisui, E,Nakamura, K,Uchida, K,Kitaguchi, T,Takahashi-Iwanaga, H,Noda, T,Aruga, J,Mikoshiba, K,Tetsuya Kitaguchi","IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism",,"Science",,"Vol. 309","No. 5744","pp. 2232-2234",2005, "Kitaguchi, T,Swartz, KJ,Tetsuya Kitaguchi","An inhibitor of TRPV1 channels isolated from funnel web spider venom",,"Biochemistry",,"Vol. 44","No. 47","pp. 15544-15549",2005, "Kitaguchi, T,Sukhareva, M,Swartz, KJ,Tetsuya Kitaguchi","Stabilizing the closed gate of the Shaker Kv channel with a hydrophobic seal",,"Biophysical Journal",,"Vol. 86","No. 1","pp. 433A",2004, "Kitaguchi, T,Sukhareva, M,Swartz, KJ,Tetsuya Kitaguchi","Stabilizing the closed S6 gate in the Shaker K-v channel through modification of a hydrophobic seal",,"Journal of General Physiology",,"Vol. 124","No. 4","pp. 319-332",2004, "Kitaguchi, T,Sukhareva, M,Swartz, KJ,Tetsuya Kitaguchi","The non-conducting mechanism of the V478W mutation in Shaker Kv channels",,"Biophysical Journal",,"Vol. 84","No. 2","pp. 219A",2003, "Sukhareva, M,Kitaguchi, T,Swartz, K,Tetsuya Kitaguchi","A mutation within the activation gate of the Shaker K+ channel decreasing single channel conductance",,"Biophysical Journal",,"Vol. 84","No. 2","pp. 74A",2003, "Kitaguchi, T,Mizugishi, K,Hatayama, M,Aruga, J,Mikoshiba, K,Tetsuya Kitaguchi","Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry",,"Development Growth & Differentiation",,"Vol. 44","No. 1","pp. 55-61",2002, "Kitaguchi, Tetsuya,Nagai, Takeharu,Nakata, Katsunori,Aruga, Jun,Mikoshiba, Katsuhiko,Tetsuya Kitaguchi","Zic3 is involved in the left-right specification of the Xenopus embryo",,"Development Growth and Differentiation",,"Vol. 43","No. Supplement","pp. S98",2001, "Kitaguchi, T,Nakata, K,Nagai, T,Aruga, J,Mikoshiba, K,Tetsuya Kitaguchi","Xenopus Polycomblike 2 (XPcl2) controls anterior to posterior patterning of the neural tissue",,"Development Genes and Evolution",,"Vol. 211","No. 6","pp. 309-314",2001, "Kitaguchi, T,Nagai, T,Nakata, K,Aruga, J,Mikoshiba, K,Tetsuya Kitaguchi","Zic3 is involved in the left-right specification of the Xenopus embryo",,"Development",,"Vol. 127","No. 22","pp. 4787-4795",2000, "Kitaguchi, T,Murata, M,Iijima, K,Kamide, K,Imagawa, T,Ikeda, Y,Tetsuya Kitaguchi","Characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib alpha: A potential substitute for platelet transfusion",,"Biochemical and Biophysical Research Communications",,"Vol. 261","No. 3","pp. 784-789",1999, "Nakata, Katsunori,Nagai, Takeharu,Koyabu, Yoshio,Kitaguchi, Tetsuya,Aruga, Jun,Mikoshiba, Katsuhiko,Tetsuya Kitaguchi","Xenopus Zic family and its role in neural and neural crest development",,"Society for Neuroscience Abstracts",,"Vol. 25","No. 1-2","pp. 526",1999, "Aruga, Jun,Nagai, Takeharu,Nakata, Katsunori,Kitaguchi, Tetsuya,Mizugishi, Kiyomi,Mikoshiba, Katsuhiko,Tetsuya Kitaguchi","Roles of Zic family in neural development",,"Neuroscience Research Supplement",,,"No. 22","pp. S42",1998, "Kitaguchi, T,Murata, M,Ambo, H,Ikeda, Y,Tetsuya Kitaguchi","Characterization of cDNA encoding full-length mouse platelet glycoprotein IX",,"Blood Coagulation & Fibrinolysis",,"Vol. 9","No. 4","pp. 381-385",1998, "Kitaguchi, T,Watanabe, N,Ambo, H,Moriki, A,Handa, M,Yagi, K,Zama, T,Isshiki, I,Watanabe, R,Murata, M,Ikeda, Y,Tetsuya Kitaguchi","Characterization of the gene encoding mouse platelet glycoprotein Ib beta.",,"Blood",,"Vol. 90","No. 10","pp. 3013",1997, "Kitaguchi, Tetsuya,Watanabe, Naohide,Ambo, Hironobu,Moriki, Takanori,Handa, Makoto,Yagi, Kanako,Zama, Takeru,Isshiki, Ikuko,Watanabe, Reiko,Murata, Mitsuru,Ikeda, Yasuo,Tetsuya Kitaguchi","Characterization of the gene encoding mouse platelet glycoprotein Ibbeta",,"Blood",,"Vol. 90","No. 10 SUPPL. 1 PART 2","pp. 69B",1997, "Moriki, T,Murata, M,Kitaguchi, T,Anbo, H,Handa, M,Watanabe, K,Takahashi, H,Ikeda, Y,Tetsuya Kitaguchi","Expression and functional characterization of an abnormal platelet membrane glycoprotein Ib alpha (Met(239)->Val) reported in patients with platelet-type von Willebrand disease",,"Blood",,"Vol. 90","No. 2","pp. 698-705",1997, "Iijima, K,Murata, M,Nakamura, K,Kitaguchi, T,Handa, M,Watanabe, K,Fujimura, Y,Yoshioka, A,Ikeda, Y,Tetsuya Kitaguchi","High shear stress attenuates agonist-induced, glycoprotein IIb/IIIa-mediated platelet aggregation when von Willebrand factor binding to glycoprotein Ib/IX is blocked",,"Biochemical and Biophysical Research Communications",,"Vol. 233","No. 3","pp. 796-800",1997, "Kitaguchi, T,Murata, R,Lijima, K,Okada, M,Amatsuji, Y,Kamide, K,Imagawa, T,Matsuda, H,Ruggeri, ZM,Ikeda, Y,Tetsuya Kitaguchi","Liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib alpha enhance ristocetin-induced platelet aggregation",,"Thrombosis and Haemostasis",,,,"pp. OC735",1997, "Kitaguchi, T,Murata, M,Ikeda, Y,Tetsuya Kitaguchi","[Establishment and characterization of transgenic mice expressing human platelet glycoprotein Ib alpha].",,"Rinsho byori. The Japanese journal of clinical pathology",,"Vol. Suppl 104",,"pp. 51-9",1997, "Okada, M,Murata, M,Suzuki, H,Kitaguchi, T,Handa, M,Watanabe, K,Sakai, K,Tanoue, K,Ikeda, Y,Tetsuya Kitaguchi","von Willebrand factor binding to glycoprotein Ib/IX induces platelet shape change under high shear stress conditions - An electron microscopic study",,"Thrombosis and Haemostasis",,,,"pp. P2626",1997, "Kitaguchi, T,Murata, M,Anbo, H,Moriki, T,Ikeda, Y,Tetsuya Kitaguchi","Characterization of the gene encoding mouse platelet glycoprotein Ib beta",,"Thrombosis Research",,"Vol. 87","No. 2","pp. 235-244",1997, "Moriki, Tokanori,Murata, Mitsuru,Kitaguchi, Tetsuya,Watanabe, Reiko,Yokoyama, Kenji,Handa, Makoto,Watanabe, Kiyoaki,Ikeda, Yasuo,Tetsuya Kitaguchi","In vitro evaluation of antiplatelet efficacy of a recombinant, soluble platelet membrane receptor derived from a variant glycoprotein Ib-alpha",,"Blood",,"Vol. 88","No. 10 SUPPL. 1 PART 1-2","pp. 34A",1996, "Kitaguchi, Tetsuya,Murata, Mitsuru,Iijima, Kaori,Okada, Mitsuhiro,Amatsuji, Yasuo,Kamiide, Kaeko,Imagawa, Takashi,Matsuda, Hiroshi,Ruggeri, Zaverio,Ikeda, Yasuo,Tetsuya Kitaguchi","Construction and functional characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein Ib-alpha",,"Blood",,"Vol. 88","No. 10 SUPPL. 1 PART 1-2","pp. 52B",1996, "Kitaguchi, T,Murata, M,Iijima, K,Okada, M,Amatsuji, Y,Kamiide, K,Imagawa, T,Matsuda, H,Ruggeri, Z,Ikeda, Y,Tetsuya Kitaguchi","Construction and functional characterization of liposomes carrying von Willebrand factor-binding domain of platelet glycoprotein lb alpha.",,"Blood",,"Vol. 88","No. 10","pp. 2935",1996, "Okada, M,Murata, M,Suzuki, H,Kitaguchi, T,Handa, M,Watanabe, K,Sakai, K,Tanoue, K,Ikeda, Y,Tetsuya Kitaguchi","Electron microscopic analysis of shear-induced platelet aggregation",,"Blood",,"Vol. 88","No. 10","pp. 2940",1996, "Okada, Mitsuhiro,Murata, Mitsuru,Suzuki, Hidenori,Kitaguchi, Tetsuya,Handa, Makoto,Watanabe, Kiyoaki,Sakai, Kiyotaka,Tanoue, Kenjiro,Ikeda, Yasuo,Tetsuya Kitaguchi","Electron microscopic analysis of shear-induced platelet aggregation",,"Blood",,"Vol. 88","No. 10 SUPPL. 1 PART 1-2","pp. 53B",1996, "Kitaguchi, T,Murata, M,Kuramochi, T,Kobayashi, K,Ito, M,Ueyama, Y,Nomura, T,Hikichi, K,Miyakawa, Y,Handa, M,Hiraoka, Y,Aiso, S,Ikeda, Y,Tetsuya Kitaguchi","Establishment and characterization of transgenic mice expressing human platelet glycoprotein Ib alpha",,"Biochemical and Biophysical Research Communications",,"Vol. 220","No. 2","pp. 418-424",1996, "Moriki, T,Murata, M,Kitaguchi, T,Watanabe, R,Yokoyama, K,Handa, M,Watanabe, K,Ikeda, Y,Tetsuya Kitaguchi","In vitro evaluation of antiplatelet efficacy of a recombinant, soluble platelet membrane receptor derived from a variant glycoprotein Ib alpha.",,"Blood",,"Vol. 88","No. 10","pp. 126",1996,