"Bo Zhu,Takanobu Yasuda,Tetsuya Kitaguchi","切らずに開く酵素スイッチ",,"日本化学会バイオテクノロジー部ニュースレター",,"Vol. 27","No. 2","Page 3-11",2024,Mar. "Bo Zhu,Yukihiko Yamasaki,Takanobu Yasuda,Cheng Qian,Zhirou Qiu,Hiroshi Ueda,Tetsuya Kitaguchi","A customizable one-pot detection system using β-glucuronidase switch and label-free antibody","化学工学会第89年会",,,,,,2024,Mar. "Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","発光酵素断片のトラップ&リリースに基づく抗原検出法","化学工学会第89年会",,,,,,2024,Mar. "Natsuki Shibukawa,Kana Sasamoto,瀬尾 秀宗,Takanobu Yasuda,Bo Zhu,太田 邦史,Hiroshi Ueda,Tetsuya Kitaguchi","バイオセンサーに変換可能な抗体の取得に向けた蛍光プローブタンパク質の開発","化学工学会第89年会",,,,,,2024,Mar. "Akihito Inoue,Bo Zhu,Takanobu Yasuda,Keisuke Mizutani,Ken Kobayashi,Tetsuya Kitaguchi","タンパク質言語モデルを用いた一変異効果予測による蛍光免疫センサーの機能向上","化学工学会第89年会",,,,,,2024,Mar. "Bo Zhu","Development of diverse immunosensors through rapid molecular evolutions and deep learning","日本生物工学会東日本支部賀詞交換会",,,,,,2024,Feb. "Bo Zhu","Molecular and whole-cell immunosensors developed by directed evolution for applications in diagnostics and food-safety control","BioTechnology Institute Seminar 2023 Fall",,,,,,2023,Nov. "Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","生物発光免疫センサーの発光活性増大機構の解明とその原理の 全長抗体への展開","第2回日本抗体学会学術大会","第2回日本抗体学会学術大会要旨集",,,,,2023,Nov. "Kana Sasamoto,Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","Efficient and rapid linker optimization with heterodimeric coiled coils improves the response of fluorescent biosensors comprising antibody and protein M",,"The Analyst",,"vol. 148",,"p. 5843-5850",2023,Oct. "岡田航輝,間部悟司,加藤晃代,Bo Zhu,Tetsuya Kitaguchi,中野秀雄","出芽酵母における翻訳促進ペプチドタグに関する研究","日本農芸化学会 中部・関西支部合同大会",,,,,,2023,Oct. "Keisuke Mizutani,Ken Kobayashi,Bo Zhu,Tetsuya Kitaguchi,Akihito Inoue","教師なしクラスタリングを用いたタンパク質機能予測","第26回情報論的学習理論ワークショップ (IBIS2023)",,,,,,2023,Oct. "Zhu, B.,Qiu, Z.,Mizutani, K.,Kobayashi, K.,Ueda, H.,Kitaguchi, T.","Rapid development of single fluorescent protein-based immunosensor Flashbody through ultra-high-throughput screening and cell-free protein synthesis","第75回?本?物?学会?会",,,,,,2023,Sept. "Takanobu Yasuda,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","抗体結合タンパク質を利用した全長抗体の生物発光センサー化","化学工学会第54回秋季大会","化学工学会第54回秋季大会要旨集",,,,,2023,Aug. "Bo Zhu,Zhe Du,Yancen Dai,Tetsuya Kitaguchi,Sebastian Behrens,Burckhard Seelig","Nanodroplet-Based Reagent Delivery into Water-in-Fluorinated-Oil Droplets",,"Biosensors",,"Vol. 13",,"pp. 768",2023,July "Satoshi Okada,Yuka Muto,Bo Zhu,Hiroshi Ueda,Hiroyuki Nakamura","Development of a Peptide Sensor Derived from Human ACE2 for Fluorescence Polarization Assays of the SARS-CoV-2 Receptor Binding Domain",,"Analytical Chemistry",," 95",," 6198-6202",2023,Apr. "Rianto Sato,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Naohiro Kato,Hiroshi Ueda","3分割ルシフェラーゼを用いた免疫測定法における相互作用の測定と数理モデルの作製","化学工学会第88年会","化学工学会第88年会要旨集",,,,,2023,Mar. "Akihito Inoue,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,村上明一,Hiroshi Ueda","酵母細胞表層提示系を用いたナノ抗体由来”nano Q-body”のTrp変異進化","化学工学会第88年会","化学工学会第88年会要旨集",,,,,2023,Mar. "Abdul Qawee Rani,Bo Zhu,Hiroshi Ueda,Tetsuya Kitaguchi","Recent progress in homogeneous immunosensors based on fluorescence or bioluminescence using antibody engineering",,"ANALYST",," 148",," 1422-1429",2023,Mar. "Bo Zhu,Cheng Qian,Haoxuan Tang,Tetsuya Kitaguchi,Hiroshi Ueda","Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces",,"Biochemistry",,,,,2023,Jan. "B. Zhu,N. Nosaka,S. Kanamaru,J. Dong,Y. Dai,A. Inoue,Y. Yang,K. Kobayashi,T. Kitaguchi,H. Iwasaki,R. Koike,K. Wakabayashi,H. Ueda","Rapid and sensitive SARS-CoV-2 detection using a homogeneous fluorescent immunosensor Quenchbody with crowding agents",,"Analyst",,"Vol. 147","Number 22","p. 4971-4979",2022,Nov. "Tomoko Tsutsumi,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫センサーQuenchbodyのシグナル増幅と高速スクリーニング法の探索","第95回日本生化学会大会","第95回日本生化学会大会要旨集",,,,,2022,Nov. "Hiroshi Ueda,Jiulong Su,Bo Zhu,Akihito Inoue,大山浩之,森田いずみ,Jinhua Dong,小西良子,Tetsuya Kitaguchi,小林典裕,三宅司郎","各種食中毒から生活者を守る「パトロール酵母」の開発",,"第74回日本生物工学会大会要旨集",,,,,2022,Oct. "Hiroshi Ueda,Bo Zhu,Jinhua Dong","Isolation of recombinant human antibody for the prevention and rapid diagnosis of COVID-19","Joint SBJ Meeting with Indonesia, Philippines, and Thailand",,,,,,2022,Oct. "Hiroshi Ueda,Bo Zhu,Jiulong Su,Tetsuya Kitaguchi,Norihiro Kobayashi,Shiro Miyake.","Development of “patrol yeasts” for the detection of multiple toxic substances in foods","The 15th Asian Congress on Biotechnology","The 15th Asian Congress on Biotechnology",,,,,2022,Oct. "Jiulong Su,Bo Zhu,Akihito Inoue,Hiroyuki Oyama,Izumi Morita,Jinhua Dong,Takanobu Yasuda,Yoshiko Sugita-Konishi,Tetsuya Kitaguchi,Norihiro Kobayashi,Shiro Miyake,Hiroshi Ueda","The Patrol Yeast: a new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning",,"Biosensors and Bioelectronics","Elsevier","Vol. 219",," 114793",2022,Oct. "Haimei Li,Bo Zhu,Baowei Li,Limei Chen,Xuerao Ning,Hang Dong,Jingru Liang,Xueying Yang,Jinhua Dong,Hiroshi Ueda","Isolation of a human SARS-CoV-2 neutralizing antibody from a synthetic phage library and its conversion to fluorescent biosensors",,"Scientific Reports","Springer Nature","vol. 12",,"p. 15496",2022,Sept. "Bo Zhu,野坂 宜之,Jinhua Dong,Tetsuya Kitaguchi,小池 竜 司,若林 健二,Hiroshi Ueda","Converting antibodies to rapid response SARS-CoV-2 homogeneous immunosensors via Quenchbody technology and crowding agent","化学工学会第53回秋季大会","化学工学会第53 回秋季大会要旨集",,,,,2022,Sept. "Akihito Inoue,Taiga Suzuki,Yinghui Yang,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","コルチゾール認識ナノ抗体の蛍光免疫センサー化","第16回バイオ関連化学シンポジウム","第16回バイオ関連化学シンポジウム要旨集",,,,,2022,Sept. "Yancen Dai,Yuko Sato,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Kimura,Farid J. Ghadess,Hiroshi Ueda","Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting",,"Chemical Science","The Royal Society of Chemistry","Vol. 13","Issue 33","p. 9739-9748",2022,Aug. "Dai Yancen,Sato Yuko,Zhu Bo,Kitaguchi Tetsuya,Kimura Hiroshi,Farid J. Ghadessy,Ueda Hiroshi","Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live-cell imaging and sorting","Bioanalytical Sensors Gordon Research Conference","Bioanalytical Sensors Gordon Research Conference",,,,,2022,June "Bo Zhu,Haimei Li,Yancen Dai,Akihito Inoue,Yinghui Yang,Kaori Kobayashi,Tetsuya Kitaguchi,Jinhua Dong,Hiroshi Ueda","Rapid construction of homogeneous immunosensors for SARS-CoV-2 nucleocapsid and spike proteins using Quenchbody and Quenchprobe technology","Bioanalytical Sensors Gordon Research Conference","Bioanalytical Sensors Gordon Research Conference",,,,,2022,June "Bo Zhu,Cheng Qian,Haoxuan Tang,Tetsuya Kitaguchi,Hiroshi Ueda.","Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces",,"bioRxiv",,,,,2022,May "Kaori Kobayashi,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫プローブQuenchprobeのダブルラベル化の検討","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Yancen Dai,Bo Zhu,Yuko Sato,Hiroshi Kimura,Farid J. Ghadessy,Tetsuya Kitaguchi,Hiroshi Ueda.","Development of an immunofluorescence probe Q-body for the direct visualization of tumor marker p53 in fixed and living cells.","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Rika Tsubaki,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Hiroshi Ueda","蛍光免疫センサーCoiled Quenchbodyのがん光線力学療法への応用","化学工学会第87年会","化学工学会第87年会要旨集",,,,,2022,Mar. "Akihito Inoue,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Akikazu Murakami,Hiroshi Ueda.","Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface.",,"Res Sq",,,,,2021,Nov. "Akihito Inoue,Takanobu Yasuda,Bo Zhu,Tetsuya Kitaguchi,Akikazu Murakami,Hiroshi Ueda","Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface",,"Scientific Reports","Springer Nature","Vol. 11",,"p. 22590",2021,Nov. "Bo Zhu,Jinhua Dong,寧雪じょう,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda","Quenchbodyを用いた1分間SARS-CoV-2及び変異株の検出法","化学工学会第52回秋季大会","化学工学会第52回秋季大会要旨集",,,,,2021,Sept. "Zhu Bo,Dong Jinhua,Xuerao Ning,Akihito Inoue,Tetsuya Kitaguchi,Hiroshi Ueda.","Development of quenchbody-based 1-minute SARS-CoV-2 detection assay.","化学工学会第86年会","化学工学会第86年会要旨集",,,,,2021,Mar. "Bo Zhu,Rui Gan,Maria D. Cabezas,Takaaki Kojima,Robert Nicol,Michael C. Jewett,Hideo Nakano","Increasing cell‐free gene expression yields from linear templates in Escherichia coli and Vibrio natriegens extracts by using DNA‐binding proteins",,"Biotechnology and Bioengineering",,"Vol. 117","Issue 12","pp. 3849-3857",2020,Aug. "Almasul Alfi,Bo Zhu,Jasmina Damnjanovic,Takaaki Kojima,Yugo Iwasaki,Hideo Nakano","Production of active manganese peroxidase in Escherichia coli by co-expression of chaperones and in?vitro maturation by ATP-dependent chaperone release",,"Journal of Bioscience and Bioengineering",,"Vol. 128","No. 3","pp. 290-295",2019,Sept. "Takaaki Kojima,Ayako Nakane,Bo Zhu,Almasul Alfi,Hideo Nakano","A simple, real-time assay of horseradish peroxidase using biolayer interferometry.",,"Bioscience, biotechnology, and biochemistry",,"Vol. 83","No. 10","pp. 1822-1828",2019,May "Takaaki Kojima,Takuro Mizoguchi,Eri Ota,Jumpei Hata,Keisuke Homma,Bo Zhu,Kiyotaka Hitomi,Hideo Nakano","Immobilization of proteins onto microbeads using a DNA binding tag for enzymatic assays.",,"Journal of bioscience and bioengineering",,,,,2015,Oct. "Bo Zhu,Takuro Mizoguchi,Takaaki Kojima,Hideo Nakano","Ultra-high-throughput screening of an in vitro-synthesized horseradish peroxidase displayed on microbeads using cell sorter.",,"PloS one",,"Vol. 10","No. 5","pp. e0127479",2015,May "KOJIMA Takaaki,ZHU Bo,NAKANO Hideo","Construction of a DNA Library on Microbeads Using Whole Genome Amplification.",,"In: Kroneis T. (eds) Whole Genome Amplification, Methods in Molecular Biology",,,,,2015,Jan. "Ryoko Ninomiya,Bo Zhu,Takaaki Kojima,Yugo Iwasaki,Hideo Nakano","Role of disulfide bond isomerase DsbC, calcium ions, and hemin in cell-free protein synthesis of active manganese peroxidase isolated from Phanerochaete chrysosporium",,"Journal of Bioscience and Bioengineering.",,"Vol. 117","No. 5","pp. 652-657",2014,May "Yan Han,Fang Chen,Nuo Li,Bo Zhu,Xianzhen Li","Bacillus marcorestinctum sp. nov., a novel soil acylhomoserine lactone quorum-sensing signal quenching bacterium.",,"International journal of molecular sciences",,"Vol. 11","No. 2","pp. 507-520",2010,Feb.