"Keijun Kakihara,Masayuki Komada,Toshiaki Fukushima","Caspase-dependent STAMBPL1 cleavage promotes cell death through its C-terminal fragment with hyperactive deubiquitinating activity","The International Symposium in Tokyo 2022 “Ubiquitin New Frontier “from Neo-Biology to Target Protein Degradation”",,,,,,2023,Dec. "Yomogita H,Ito H,Hashimoto K,Kudo A,Fukushima T,Endo T,Hirate Y,Akimoto Y,Komada M,Kanai Y,Miyasaka N,Kanai-Azuma M","A possible function of Nik-related kinase in the labyrinth layer of delayed delivery mouse placentas",,"J Reprod Dev Mol",,"Vol. 69","No. 1","Page 32-40",2022,Dec. "Keijun Kakihara,Masayuki Komada,Toshiaki Fukushima","Cis-activity regulation of USP8 and STAMBPL1, two endosomal deubiquitinating enzymes, and role of dysregulation in disease onset","TMiMS国際シンポジウム「New Frontiers in Ubiquitin Proteasome System」",,,,,,2022,Dec. "Gai Ando,Keijun Kakihara,Masayuki Komada,Toshiaki Fukushima","Molecular mechanisms underlying the over-activation of USP8 and USP48 by Cushing’s disease-associated mutations","The International Symposium in Tokyo 2022 “Ubiquitin New Frontier “from Neo-Biology to Target Protein Degradation”",,,,,,2022,Dec. "福嶋 俊明,柿原 慧遵,浅水 謙吾,森次 圭,北口 哲也,駒田 雅之","クッシング病を引き起こすUSP8の過剰活性化機構","第95回 日本生化学会大会シンポジウム「ユビキチンワールドを制御する脱ユビキチン化酵素の疾患、創薬における重要性」","第95回日本生化学会大会要旨集",,,,,2022,Nov. "Marsya Yonna Nurrachma,Beni Lestari,駒田 雅之,福嶋 俊明","Ubiquitination-mediated activation of AKT and its cancer-associated mutants","第45回 日本分子生物学会年会",,,,,,2022,Nov. "西岡 柚香,柿原 慧遵,遠藤 彬則,駒田 雅之,福嶋 俊明","脱ユビキチン化酵素USP8によるVAMP8の制御とその細胞質分裂における意義の解明","第45回 日本分子生物学会年会",,,,,,2022,Nov. "Keijun Kakihara,Kei Moritsugu,Tetsuya Kitaguchi,Akinori Endo,Masayuki Komada,Toshiaki Fukushima","Autoinhibition of USP8 by WW-like domain and the dysregulation in Cushing’s disease","EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”","EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”",,,,,2022,Sept. "福嶋 俊明,柿原 慧遵,駒田 雅之","脱ユビキチン化酵素USP8の遺伝子変異を介したクッシング病の発症メカニズム","第27回 日本病態プロテアーゼ学会学術集会",,,,,,2022,Aug. "Beni Lestari,Satomi Naito,Akinori Endo,Hidenori Nishihara,Akira Kato,Erika Watanabe,Kimitoshi Denda,Masayuki Komada,Toshiaki Fukushima","Placental Mammals Acquired Functional Sequences in NRK for Regulating the CK2?PTEN?AKT Pathway and Placental Cell Proliferation",,"Molecular Biology and Evolution",,"Vol. 39","No. 2","p. msab371",2022,Feb. "蓬田裕,高峰愛幸,伊藤日加瑠,平手良和,福嶋俊明,駒田雅之,金井克晃,宮坂尚幸,金井正美","マウス、ヒト胎盤におけるNrk下流遺伝子群と分娩遅延の関連について","日本分子生物学会年会",,,,,,2021,Dec. "BENI Lestari,内藤 聡美,遠藤 彬則,西原 秀典,加藤 明,渡邊 恵理香,傳田 公紀,駒田 雅之,福嶋 俊明","Comparative Phylogenetic Analysis and Molecular Characterization Reveal Eutherian-Specific Role of NRK in Regulating Placenta Development","日本分子生物学会年会",,,,,,2021,Dec. "氷見 雄哉,柿原 慧遵,加藤 明,駒田 雅之,福嶋 俊明","脱ユビキチン酵素USP8はレンチウイルス粒子へのウイルスRNAの動員を阻害することによってウイルスの増殖を防ぐ","日本分子生物学会年会",,,,,,2021,Dec. "柿原慧遵,浅水謙吾,森次圭,北口哲也,遠藤彬則,木寺詔記,池口満徳,駒田雅之,福嶋俊明","脱ユビキチン化酵素USP8の自己阻害機構とクッシング病関連変異によるその解除","第44回日本分子生物学会年会","第44回日本分子生物学会年会要旨集",,,,,2021,Dec. "Keijun Kakihara,Kengo Asamizu,Kei Moritsugu,Masahide Kubo,Tetsuya Kitaguchi,Akinori Endo,Akinori Kidera,Mitsunori Ikeguchi,Akira Kato,Masayuki Komada,Toshiaki Fukushima.","Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.",,"Commun Biol",," 4",," 1272",2021,Nov. "Keijun Kakihara,Kengo Asamizu,Kei Moritsugu,Masahide Kubo,Tetsuya Kitaguchi,Akinori Endo,Akinori Kidera,Mitsunori Ikeguchi,Akira Kato,Masayuki Komada,Toshiaki Fukushima","The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain",,"bioRxiv",,,,,2021,May "福嶋俊明,遠藤彬則,川口紘平,円由香,駒田雅之","クッシング病の治療薬開発を目指したUSP8-STAM1複合体を作用点とするACTH分泌制御物質の開発","第6回橋渡し研究戦略的推進プログラムシンポジウム",,,,,,2021,Mar. "Mattioni A,Boldt K,Auciello G,Rappoport JZ,Ueffing M,Castagnoli L,Cesareni G,Santonico E.,Anna Mattioni,Karsten Boldt,Giulio Auciello,Masayuki Komada,Joshua Z Rappoport,Marius Ueffing,Luisa Castagnoli,Gianni Cesareni,Elena Santonico","Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family.",,"The FEBS Journal",,"Vol. 287","No. 16","pp. 3526-3550",2020,Aug. "Satomi Naito,Toshiaki Fukushima,Akinori Endo,Kimitoshi Denda,Masayuki Komada","Nik-related kinase is targeted for proteasomal degradation by the chaperone-dependent ubiquitin ligase CHIP",,"FEBS Letters",," 594"," 11"," 1778-1786",2020,Mar. "Keijun Kakihara,Kengo Asamizu,Akinori Endo,Kei Moritsugu,Akira Kato,Masayuki Komada,Toshiaki Fukushima","The enzyme activity of USP8 is regulated by the intramolecular interaction of the USP domain and the WW domain","新学術領域「ケモユビキチン」第3回班会議",,,,,,2019,Dec. "KIMITOSHI DENDA,Kanako Ida,Masataka Tanno,Kanako Nakao-Wakabayashi,Masayuki Komada,nobuhiro hayashi","Proteomic analysis of Nrk gene-disrupted placental tissue cells explains physiological significance of NRK",,"BMC research notes",,"Vol. 12","No. 1","p. 785",2019,Dec. "Toshiaki Fukushima,Yuka Madoka,Akinori Endo,Kohei Kawaguchi,Saki Arakaki,Masayuki Komada","Constitutive formation of USP8-STAM1 complex plays an important role in the onset of Cushing’s disease","The 2019 joint meeting of the American Society for Cell Biology (ASCB) and European Molecular Biology Organization (EMBO)",,,,,,2019,Dec. "Keijun Kakihara,Kengo Asamizu,Akinori Endo,Masayuki Komada,Toshiaki Fukushima","A novel autoinhibitory mechanism of ubiquitin-specific protease 8 activity via the intramolecular interaction","The 2019 joint meeting of the American Society for Cell Biology (ASCB) and European Molecular Biology Organization (EMBO)",,,,,,2019,Dec. "Satomi Naito,Akinori Endo,Kimitoshi Denda,Yuka Madoka,Akira Kato,Masayuki Komada,Toshiaki Fukushima","Nrk prevents hyperplasia by modulating CK2-PTEN-Akt signaling pathway","The 2019 joint meeting of the American Society for Cell Biology (ASCB) and European Molecular Biology Organization (EMBO)",,,,,,2019,Dec. "Satomi Naito,Akinori Endo,Kimitoshi Denda,Akira Kato,Masayuki Komada,Toshiaki Fukushima","Nik-related kinase is regulated by quality control ubiquitin ligase CHIP","新学術領域「ケモユビキチン」第3回班会議",,,,,,2019,Dec. "Kimitoshi Denda,Kanako Ida,Masataka Tanno Kanako Nakao-Wakabayashi,Masayuki Komada,Nobuhiro Hayashi","Proteomic analysis of Nrk gene-disrupted placental tissue cells explains physiological significance of NRK",,"BMC research notes",,"Vol. 12","No. 1","pp. 785",2019,Nov. "Keishi Fukuura,Yasumichi Inoue,Chiharu Miyajima,Shin Watanabe,Muneshige Tokugawa,Daisuke Morishita,Nobumichi Ohoka,Masayuki Komada,Hidetoshi Hayashi","The ubiquitin-specific protease USP17 prevents cellular senescence by stabilizing the methyltransferase SET8 and transcriptionally repressing p21",,"The journal of biological chemistry",,"Vol. 294","No. 44","pp. 16429-16439",2019,Nov. "Keijun Kakihara,Kengo Asamizu,Akinori Endo,Masayuki Komada,Toshiaki Fukushima","A novel autoinhibitory mechanism of ubiquitin-specific protease 8 activity via the intramolecular interaction","The 92nd Annual Meeting of the Japanease Biochemical Society",,,,,,2019,Sept. "柿原 慧遵,浅水 謙吾,遠藤 彬則,駒田 雅之,福嶋 俊明","脱ユヒ?キチン化酵素 USP8 の自己活性抑制機構","2019年度日本生化学会関東支部例会",,,,,,2019,June "WH. Chan,M. Komada,T. Fukushima,EM. Southard-Smith,CR. Anderson. MJ. Wakefield","RNA-seq of Isolated Chromaffin Cells Highlights the Role of Sex-Linked and Imprinted Genes in Adrenal Medulla Development",,"Scientific Reports",,"Vol. 9","No. 1","Page 3929",2019,Mar. "Ryohei Sakai,Ryosuke Fukuda,Shin Unida,Misaki Aki,Yuji Ono,Akinori Endo,Satoshi Kusumi,Daisuke Koga,Toshiaki Fukushima,Masayuki Komada,Tsukasa Okiyoneda","The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors",,"Journal of cell science",,"Vol. 132","No. 3","pp. 228007",2019,Feb. "Ryohei Sakai,Ryosuke Fukuda,Shin Unida,Misaki Aki,Yuji Ono,Akinori Endo,Satoshi Kusumi,Daisuke Koga,Toshiaki Fukushima,Masayuki Komada,Tsukasa Okiyoneda","The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors",,"Journal of cell science",,"Vol. 132","No. 3","pp. 228007",2019,Feb. "柿原慧遵,浅水謙吾,遠藤彬則,駒田雅之,福嶋俊明","脱ユビキチン化酵素USP8の自己活性抑制機構","第2回ユビキチン研究会",,,,,,2019,Jan. "Akinori Endo,Toshiaki Fukushima,Masayuki Komada","A deubiquitinase USP8, a master regulator of endosome-centered membrane traffic, controls inter-cellular signal transduction.","Annual Meeting of the Molecular Biology Society of Japan",,,,,,2018,Nov. "Satomi Naito,Akinori Endo,Toshiaki Fukushima,Kimitoshi Denda,Akira Kato,Masayuki Komada","Molecular mechanisms underlying the control of Nrk protein levels and Nrk-mediated anti-proliferation effects","Annual Meeting of the Molecular Biology Society of Japan",,,,,,2018,Nov. "Takahiro Sawada,Kazuya Inoko,Kohei Kawaguchi,Akinori Endo,Yasushi Saeki,Keiji Tanaka,Toshiaki Fukushima,Masayuki Komada","Nuclear localization mechanism of deubiquitinating enzyme USP8 in Cushing’s disease","Annual Meeting of the Molecular Biology Society of Japan",,,,,,2018,Nov. "H. Furuta,H. Yoshihara,T. Fukushima,Y. Yoneyama,A. Ito,C. Worrall,A. Girnita,L. Girnita,M. Yoshida,T. Asano,M. Komada,N. Kataoka,K. Chida,F. Hakuno,SI. Takahashi","IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line",,"Oncotarget",,"Vol. 9","No. 74","Page 33871-33883",2018,Sept. "福嶋俊明,澤田崇広,猪子和也,待鳥卓,遠藤彬則,駒田雅之","脱ユビキチン化酵素USP8の遺伝子変異に起因するACTH過剰産生の分子機構","第2回 POMC研究者の集い",,,,,,2018,Sept. "待鳥 卓,猪子 和也,川口 紘平,遠藤 彬則,福嶋 俊明,駒田 雅之","USP8 遺伝子のゲノム編集によるCushing 病モデル細胞の作製と解析","第33回日本下垂体研究会学術集会",,,,,,2018,Aug. "Julia Saifetiarova,Martin Paukert,Masayuki Komada,Manzoor A Bhat","Reorganization of Destabilized Nodes of Ranvier in β IV Spectrin Mutants Uncovers Critical Timelines for Nodal Restoration and Prevention of Motor Paresis",,"The Journal of neuroscience",,"Vol. 38","No. 28","pp. 6267-6282",2018,July "Kohei Kawaguchi,Akinori Endo,Toshiaki Fukushima,Masayuki Komada","Ubiquitin-specific protease 8 suppresses collagen secretion by deubiquitinating Sec31","Cell and Developmental Biology Meeting",,,,,,2018,June "Xie Xuan,Shunsuke Matsumoto,Akinori Endo,Toshiaki Fukushima,Hiroyuki Kawahara,Yasushi Saeki,Masayuki Komada","Deubiquitinases USP5 and USP13 are recruited to and regulate heat-induced stress granules by deubiquitinating activities.","Cold Spring Harbor Asia Conferences, Ubiquitin Family, Autophagy and Diseases",,,,,,2018,Apr. "川口紘平,卯尾和音,田中利明,駒田雅之","脱ユビキチン化酵素の基質特異性改変に成功",,"科学新聞",,,,,2017,Apr. "Kohei Kawaguchi,Kazune Uo,Toshiaki Tanaka,Masayuki Komada.","Choosing the right substrate for the right function: role of ubiquitin-interacting motifs on ubiquitin-specific proteases",,"Tokyo Tech News",,,,,2017,Apr. "Kohei Kawaguchi,Kazune Uo,Toshiaki Tanaka,Masayuki Komada","Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25",,"Scientific Reports","Springer Nature Publishing","vol. 7",,,2017,Mar. "川口紘平,卯尾和音,田中利明,駒田雅之","脱ユビキチン化酵素の基質特異性を改変することに成功-複雑なタンパク質の制御機構の一端を解明-",,"生命理工ニュース",,,,,2017,Mar. "川口紘平,卯尾和音,田中利明,駒田雅之","脱ユビキチン化酵素の基質特異性を改変することに成功 ―複雑なタンパク質の制御機構の一端を解明―",,"東工大ニュース",,,,,2017,Mar. "田中利明,駒田雅之","母性Cyclin E-DNMT1新規複合体によるツメガエル尾部形成のエピジェネティックな制御","第39回日本分子生物学会",,,,,,2016,Nov. "柳川 享世,傳田 公紀,稲谷 卓也,田中 利明,福嶋 俊明,Nobue Kumaki,稲垣 豊,駒田 雅之","乳がんを抑制する新たな遺伝子を発見",,"大学ジャーナル",,,,,2016,Sept. "柳川 享世,傳田 公紀,稲谷 卓也,田中 利明,福嶋 俊明,Nobue Kumaki,稲垣 豊,駒田 雅之","乳がんを抑制する新たな遺伝子を発見―ヒト乳がんの診断・治療への応用に期待―",,,"東工大ニュース",,,,2016,Sept. "Masayuki Komada","The Ankrd13 Family of Ubiquitin-interacting Motif-bearing Proteins Regulates Valosin-containing Protein/p97 Protein-mediated Lysosomal Trafficking of Caveolin 1",,"J. Biol. Chem.",,,,,2016,Mar. "Masayuki Komada","The USP8 mutational status may predict drug susceptibility in corticotroph adenomas of Cushing's disease",,"Eur. J. Endocrinol.",,,,,2016,Feb. "駒田雅之","クッシング病の原因遺伝子と発症機構",,"Annual Review 糖尿病・代謝・内分泌 2016",,,,"pp. 180-186",2016,Jan. "駒田雅之","脱ユビキチン化酵素によるエンドサイトーシス制御と遺伝子疾患",,"医学のあゆみ",,"Vol. 256",,"pp. 15881-15887",2016,Jan. "駒田雅之","増殖因子受容体の分解制御と制癌",,"バイオ研究のフロンティア3 − 医療・診断をめざす先端バイオテクノロジー",,,,,2016, "卯尾和音,田中利明,駒田雅之","脱ユビキチン化酵素USP25におけるユビキチン結合モチーフUIMの機能","第38回日本分子生物学会、第88回日本生化学会 合同大会",,,,,,2015,Dec. "Masayuki Komada","The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease",,"J. Clin. Endocrinol. Metab.",,,,,2015,July "Masayuki Komada","Decoding the genetic basis of Cushing's disease: USP8 in the spotlight",,"Eur. J. Endorinol.",,"Vol. 173",,"pp. M73-M83",2015,May "Masayuki Komada","The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc",,"Proc. Natl. Acad. Sci. USA",,,,,2015,Mar. "駒田雅之","見えてきたユビキチンを介する核小体の多彩な機能",,"ファルマシア",,"Vol. 51",,"pp. 300-304",2015,Jan. "駒田雅之","難病“クッシング病”発症の分子メカニズム",,"バイオサイエンスとインダストリー",,"Vol. 73",,"pp. 300-301",2015,Jan. "駒田雅之","脱ユビキチン化酵素USP8の機能獲得型変異がクッシング病を引き起こす",,"ACTH Related Peptides",,"Vol. 26",,"pp. 56-58",2015,Jan. "駒田雅之","脱ユビキチン化酵素USP8変異とCushing病",,"クッシング症候群診療マニュアル 改訂2版",,,,"pp. 259-260",2015,Jan. "Masayuki Komada","Mutations in the deubiquitinase gene USP8 cause Cushing's disease",,"Nat. Genet.",,,,,2015,Jan. "駒田雅之","脱ユビキチン化酵素USP8の機能獲得型変異がクッシング病を引き起こす",,"ライフサイエンス新着論文レビュー First Author’s",,,,,2015,Jan. "Masayuki Komada","In vivo assembly of the axon initial segment in motor neurons",,"Brain Struct. Funct.",,,,,2014,July "Hidetaka Tanno,Takeshi Shigematsu,Shuhei Nishikawa,Akira Hayakawa,Kimitoshi Denda,Toshiaki Tanaka,Masayuki Komada","Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37",,"Journal of Biological Chemistry",,"vol. 289",,"pp. 2415-2423",2014, "Masayuki Komada","Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS",,"Histochem. Cell Biol.",,,,,2013,Aug. "Masayuki Komada","The ubiquitin code and its decoding machinery in the endocytic pathway",,"J. Biochem.",,"Vol. 153",,"pp. 497-504",2013,Apr. "駒田雅之","ユビキチン化によるFrizzledのリソソーム分解を介したWntシグナル強度の制御",,,,"Vol. 32",,"pp. 396-400",2013,Jan. "X.Li,Y.Bian,Y.Takizawa,T.Hashiomoto,N.Kitamura,T.Ikoma,J.Tanaka,Y.Inagaki,M.Komada,T.Tanaka","ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression.",,"Molecular Cancer Research",,"vol. 11",,"pp. 1437-1447",2013, "Masayuki Komada","The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane",,"Mol. Biol. Cell",,,,,2012,Apr. "Masayuki Komada","Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves",,"Mol. Cell. Biol.",,,,,2012,Jan. "Masayuki Komada","Balanced ubiquitination determines cellular responsiveness to extracellular stimul",,"Cell. Mol. Life Sci.",,"Vol. 69",,"pp. 4007?4016",2012,Jan. "Masayuki Komada","Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor",,"J. Biol. Chem.",,,,,2011,Aug. "Masayuki Komada","Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor",,"Nat. Commun.",,,,,2011,Jan. "駒田雅之","ユビキチン化による核小体の構造と機能の制御",,"生体の科学",,"Vol. 62",,"pp. 422-423",2011,Jan. "Masayuki Komada","Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis",,"J. Neuropathol. Exp. Neurol.",,,,,2010,Oct. "Masayuki Komada","Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt",,"EMBO J.",,,,,2010,July "Masayuki Komada","Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay",,"Am. J. Hum. Genet.",,,,,2010,June "Masayuki Komada","Involvement of a membrane skeletal protein, 4.1G, for Sertoli/germ cell interaction",,"Reproduction",,,,,2010,May "駒田雅之","軸索に特異的なスペクトリン細胞膜骨格の機能",,"生体の科学",,"Vol. 61",,"pp. 498-499",2010,Jan. "駒田雅之","脱ユビキチン化酵素群の細胞機能",,"脱ユビキチン化酵素群の細胞機能",,"Vol. 82",,"pp. 378-387",2010,Jan. "駒田雅之","受容体のユビキチン化と脱ユビキチン化を介した細胞のWnt応答性の制御",,"細胞工学",,"Vol. 29",,"pp. 1237-1243",2010,Jan. "駒田雅之","増殖因子受容体の分解制御と制癌",,"バイオ研究のフロンティア3 − 医療・診断をめざす先端バイオテクノロジー",,,,,2009,Oct. "Masayuki Komada","Nucleophosmin/B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36",,"J. Biol. Chem.",,,,,2009,Oct. "Masayuki Komada","Dispensable role of protein 4.1B/DAL-1 in rodent adrenal medulla regarding generation of pheochromocytoma and plasmalemmal localization of TSLC1",,,,,,,2009,Mar. "Masayuki Komada","Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36",,"J. Cell Sci.",,,,,2009,Mar. "駒田雅之","核小体の機能のユビキチンダイナミクスによる制御",,"生体の科学",,"Vol. 60",,"pp. 521-526",2009,Jan. "駒田雅之","ユビキチン修飾系による細胞質分裂の制御",,"蛋白質核酸酵素",,"Vol. 54",,"pp. 11-19",2009,Jan. "Masayuki Komada","Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains",,"Nature",,,,,2008,Sept. "Masayuki Komada","Sodium channel cluster, betaIV-spectrin and ankyrinG positive "hot spots" on dendritic segments of parvalbumin-containing neurons and some other neurons in the mouse and rat main olfactory bulbs",,"Neurosci. Res.",,,,,2008,Aug. "Masayuki Komada","Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2",,"Biochem. J.",,,,,2008,May "Masayuki Komada","Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis",,"J. Cell Sci.",,,,,2008,Apr. "駒田雅之","アミノ酸とヌクレオチドの代謝",,"バイオ系のための基礎化学問題集 − 生物化学・有機化学・物理化学",,,,,2008,Mar. "Masayuki Komada","Controlling receptor downregulation by ubiquitination and deubiquitination",,"Curr. Drug Discov. Technol.",,"Vol. 5",,"pp. 78-84",2008,Mar. "駒田雅之","エンドソームと細胞質分裂の接点−ユビキチン化/脱ユビキチン化による調節",,"蛋白質核酸酵素",,"Vol. 53",,"pp. 2094-2098",2008,Jan. "Masayuki Komada","Interaction of membrane skeletal protein, protein 4.1B and p55, and sodium bicarbonate cotransporter 1 in mouse renal S1-S2 proximal tubules",,"J. Histochem. Cytochem.",,,,,2007,Aug. "Masayuki Komada","14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase",,"Exp. Cell Res.",,,,,2007,Aug. "Masayuki Komada","Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein",,"J. Biol. Chem.",,,,,2007,Aug. "駒田雅之","輸送タンパク質は体内の宅配便",,"トコトンやさしいタンパク質の本",,,,,2007,Feb. "Masayuki Komada","Regulation of endosomal cargo sorting by deubiquitinating enzymes",,"Research Advances in Biological Chemistry",,,,"pp. 27-38",2007,Jan. "駒田雅之","神経繊維ランビエ絞輪部近傍の軸索構築に関するタンパク質間相互作用",,"生体の科学",,"Vol. 58",,"pp. 476-477",2007,Jan. "駒田雅之,水野英美","エンドソームにおけるメンブレントラフィックの脱ユビキチン化による調節",,,"細胞工学","Vol. 25","No. 11","pp. 1258-1263",2006,Nov. "Mizuno, E.,Kobayashi, K.,Yamamoto, A.,Kitamura, N.,Komada, M.","A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes",,"Traffic",,"Vol. 7",,"pp. 1017-1031",2006, "Uemoto, Y.,Suzuki, S.,Terada, N.,Ohno, N.,Ohno, S.,Yamanaka, S.,Komada, M.","Specific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of Ranvier.",,"J. Biol. Chem.",,,,"pp. 10.1074/jbc.M609223200",2006, "Nishimura, K.,Akiyama, H.,Komada, M.,Kamiguchi, H.","betaIV-spectrin forms a diffusion barrier against L1CAM at the axon initial segment.",,"Mol. Cell. Neurosci.",,,,"pp. 10.1016/j.men.2006.11.017",2006, "Nakamura, N.,Tanaka, N.,Kitamura, N.,Komada, M.","Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.",,"Genes Cells",,"Vol. 11",,"pp. 593-606",2006, "Ohno, N.,Terada, N.,Yamakawa, H.,Komada, M.,Ohara, O.,Trapp, B. D.,Ohno, S.","Expression of protein 4.1G in Schwann cells of the peripheral nervous system",,"J. Neurosci. Res.",,"Vol. 84",,"pp. 568-577",2006, "Yamasaki, A.,Tani, K.,Yamamoto, A.,Kitamura, N.,Komada, M.","The Ca2+-binding protein ALG-2 is recruited to ER exit sites by Sec31A and stabilizes the localization of Sec31A",,"Mol. Biol. Cell",,"Vol. 17",,"pp. 4876-4887",2006, "Mizuno, E.,Iura, T.,Mukai, A.,Yoshimori, T.,Kitamura, N.,Komada, M.","Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes.",,"Mol. Biol. Cell",,"Vol. 16",,"pp. 5163-5174",2005, "Komada, M.,Kitamura, N","The Hrs/STAM complex in the downregulation of receptor tyrosine kinases.",,"J. Biochem.",,"Vol. 137",,"pp. 1-8",2005, "駒田雅之","軸索起始部とランビエ絞輪へのNaチャネル局在化機構",,"生体の科学","生体の科学","Vol. 56","No. 3","pp. 221-225",2005, "駒田雅之","受容体チロシンキナーゼのユビキチン化による分解機構",,"現代医療","現代医療","Vol. 36",,"pp. 93-99",2004, "Morino, C.,Kato, M.,Yamamoto, A.,Mizuno, E.,Hayakawa, A.,Komada, M.,Kitamura, N.","A role for Hrs in endosomal sorting of ligand-stimulated and unstimulated epidermal growth factor receptor.",,"Exp. Cell Res.",,"Vol. 297",,"pp. 380-391",2004, "駒田雅之","ホスファチジルイノシトール3?リン酸とエンドソームにおける膜輸送",,"ファルマシア","ファルマシア","Vol. 40",,"pp. 635-639",2004, "Mizuno, E.,Kawahata, K.,Okamoto, A.,Kitamura, N.,Komada, M.","Association with Hrs is required for the early endosomal localization, stability, and function of STAM",,"J. Biochem.",,"Vol. 135",,"pp. 385-396",2004, "Mizuno, E.,Kawahata, K.,Kato, M.,Kitamura, N.,Komada, M.","STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif.",,"Mol. Biol. Cell",,"Vol. 14",,,2003, "Kunzmann, S.,Wohlfahrt, J.G.,Itoh, S.,Asao, H.,Komada, M.,Akdis, C.A.,Blaser, K.,Schmidt-Weber, C.B.","SARA and Hrs attenuate susceptibility to TGF-beta1-mediated T cell suppression.",,"FASEB J.",,"Vol. 17",,"pp. 194-202",2003, "Komada, M.,Soriano, P","betaIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier.",,"J. Cell Biol.",,"Vol. 156",,"pp. 337-348",2002, "Sun,C.-X.,Haipek, C.,Scoles, D.R.,Pulst, S.M.,Giovannini, M.,Komada, M.,Gutmann, D.H.","Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, Hrs (hepatocyte growth factor-regulated tyrosine kinase substrate).",,"Hum. Mol. Genet.",,"Vol. 11",,"pp. 3167-3178",2002, "Komada, M.,Kitamura, N.","Hrs and Hbp: possible regulators of endocytosis and exocytosis",,"Biochem. Biophys. Res. Commun.",,"Vol. 281",,"pp. 1065-1069",2001, "Komada, M.,McLean, D.J.,Griswold, M.D.,Russell, L.D.,Soriano, P.","E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis",,"Genes Dev.",,"Vol. 14",,"pp. 1332-1342",2000, "駒田雅之","FYVEフィンガータンパク質Hrsのマウス発生における役割",,"実験医学","実験医学","Vol. 17","No. 13","pp. 1655-1658",1999, "Komada, M.,Soriano, P.","Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis",,"Genes Dev.",,"Vol. 13",,"pp. 1475-1485",1999, "Masayuki Komada","Human Hrs, a tyrosine kinase substrate in growth factor-stimulated cells: cDNA cloning and mapping of the gene to chromosome 17",,"Gene",,"Vol. 213",,"pp. 125-132",1998, "Komada, M.,Masaki, R.,Yamamoto, A.,Kitamura, N.","Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes",,"J. Biol. Chem.",,"Vol. 272",,"pp. 20538-20544",1997, "Masayuki Komada","Vascular endothelial growth factor expression in choroidal neovascularization in rats",,"Graefe's Arch. Clin. Exp. Ophthalmol.",,"Vol. 235",,"pp. 313-319",1997, "Komada, M.,Kitamura, N","Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain",,"Mol. Cell. Biol.",,"Vol. 15",,"pp. 6213-6221",1995, "駒田雅之","Hepatocyte growth factor/scatter factor受容体の構造と機能に関する研究",,,,,,,1994, "Komada, M.,Kitamura, N.","Regulatory role of major tyrosine autophosphorylation site of kinase domain of c-Met receptor (scatter factor/hepatocyte growth factor receptor)",,"J. Biol. Chem.",,"Vol. 269",,"pp. 16131-16136",1994, "Masayuki Komada","Gene expression and regulation of HGF-SF",,"Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and the C-Met Receptor","Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and the C-Met Receptor",,,,1993, "Komada, M.,Hatsuzawa, K.,Shibamoto, S.,Ito, F.,Nakayama, K.,Kitamura, N.","Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin",,"FEBS Lett.",,"Vol. 328",,"pp. 25-29",1993, "Masayuki Komada","Evidence for involvement of furin in cleavage and activation of diphtheria toxin",,"J. Biol. Chem.",,"Vol. 268",,"pp. 26461-26465",1993, "Komada, M.,Kitamura, N.","The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor",,"Oncogene",,"Vol. 8",,"pp. 2381-2390",1993, "Komada, M.,Miyazawa, K.,Ishii, T.,Kitamura, N.","Characterization of hepatocyte-growth-factor receptors on Meth A cells",,"Eur. J. Biochem.",,"Vol. 204",,"pp. 857-864",1992, "Masayuki Komada","Detection of three distinct phospholipases A2 in cultured mast cells",,"J. Biochem.",,"Vol. 111",,"pp. 175-181",1992, "Masayuki Komada","Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains",,"Biochemistry",,"Vol. 31",,"pp. 9555-9561",1992, "駒田雅之","ラットII型ホスホリパーゼA2の遺伝子のクローニングと構造解析",,,,,,,1990, "Komada, M.,Kudo, M.,Inoue, K.","Structure of gene coding for rat group II phospholipase A2",,"Biochem. Biophy. Res. Commun.",,"Vol. 168",,"pp. 1059-1065",1990, "Komada, M.,Kudo, I.,Mizushima, H.,Kitamura, N.,Inoue, K.","Structure of cDNA coding for rat platelet phospholipase A2",,"J. Biochem.",,"Vol. 106",,"pp. 545-547",1989,