"Masa-aki Kawano,Koji Doi,Hajime Fukuda,Yoshinori Kita,Imai Kensuke,Takamasa Inoue,Teruya Enomoto,Masanori Matsui,Mamoru Hatakeyama,Yuki Yamaguchi,Hiroshi Handa","SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes",,"Biotechnol. Rep.",,"Vol. 5",,"pp. 105-111",2015,Mar.
"Shuji Iida,Kensuke Imai,Sachiko Matsuda,Osamu Itano,Mamoru Hatakeyama,Satoshi Sakamoto,Daisuke Kokuryo,Koji Okabayashi,Takashi Endo,Yoshiyuki Ishii,Hirotoshi Hasegawa,Ichio Aoki,Hiroshi Handa,Yuko Kitagawa","In vivo identification of sentinel lymph nodes using MRI and size-controlled and monodispersed magnetite nanoparticles",,"Journal of Magnetic Resonance Imaging",,"Vol. 38","No. 6","pp. 1346?1355",2013,Nov.
"Teruya Enomoto,Masaaki Kawano,Hajime Fukuda,Wataru Sawada,Takamasa Inoue,Kok Chee Haw,Yoshinori Kita,Satoshi Sakamoto,Takeshi Imai,Mamoru Hatakeyama,Shigeyoshi Saito,Adarsh Sandhu,Masanori Matsui,Ichio Aoki,Hiroshi Handa","Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1",,"Journal of Biotechnology",,"Vol. 167","No. 1","pp. 8-15",2013,Aug.
"Teruya Enomoto,Masa-aki Kawano,Hajime Fukuda,Wataru Sawada,Takamasa Inoue,Kok Chee Haw,Yoshinori Kita,Satoshi Sakamoto,Yuki Yamaguchi,Takeshi Imai,Mamoru Hatakeyama,Shigeyoshi Saito,Adarsh Sandhu,Masanori Matsui,Ichio Aoki,Hiroshi Handa","Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1",,"J. Biotechnol.",,"Vol. 167","No. 1","pp. 8-15",2013,Aug.
"Satoshi Sakamoto,Mamoru Hatakeyama,Takumi Ito,Hiroshi Handa","Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound",,"Bioorganic & Medicinal Chemistry",,"Vol. 20","No. 6","pp. 1990?2001",2012,Mar.
"畠山士,半田宏","ナノ融合による先進バイオデバイス",,"バイオテクノロジーシリーズ","シーエムシー出版",,,"pp. 8-17",2011,Dec.
"畠山士,加部泰明,半田宏","ナノ粒子分散系の基礎と応用",,"CMCテクニカルライブラリー―ファインケミカルシリーズ","シーエムシー出版",,,,2011,Nov.
"Mamoru Hatakeyama,Hiroshi Kishi,Yoshinori Kita,Kensuke Imai,Kosuke Nishio,Satoki Karasawa,Yuka Masaike,Satoshi Sakamoto,Adarsh Sandhu,Akihiro Tanimoto,Tatsuya Gomi,Eiichi Kohda,Masanori Abe,Hiroshi Handa","A two-step ligand exchange reaction generates highly water-dispersed magnetic nanoparticles for biomedical applications",,"Journal of Materials Chemistry",,"Vol. 21","No. 16","pp. 5959-5966",2011,Mar.
"半田宏,畠山士","コアシェル微粒子の設計・合成技術・応用の展開",,,"シーエムシー出版",,,"p. 204-214",2010,July
"Masaki Hiramoto,Naoya Maekawa,Takeshi Kuge,Fumiaki Ayabe,Atsushi Watanabe,Yuka Masaike,Mamoru Hatakeyama,Hiroshi Handa,Takeshi Imai","High-performance affinity chromatography method for identification of L-arginine interacting factors using magnetic nanobeads",,"Biomedical Chromatography",,"Vol. 24","No. 6","pp. 606?612",2010,June
"Aiko Tominaga,Hideki Sugawara,Toshitaka Futagawa,Kazuhiko Inoue,Kazuki Sasaki,Naoto Minamino,Mamoru Hatakeyama,Hiroshi Handa,Atsuro Miyata","Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene",,"Genes to Cells",,"Vol. 15","No. 6","pp. 595?606",2010,June
"Yasuaki Kabe,Mamoru Hatakeyama,Satoshi Sakamoto,KOSUKE NISHIO,Hiroshi Handa","Novel Applications of Affinity Beads",,"PROTEIN TARGETING WITH SMALL MOLECULES, Chemical Biology Techniques and Applications","Jhon Wiley & Sons. Inc.",,,,2009,
"Satoshi Sakamoto,Yasuaki Kabe,Mamoru Hatakeyama,Yuki Yamaguchi,Hiroshi Handa","Development and application of high-performance affinity beads: toward chemical biology and drug discovery",,"Chem. Rec.",,"  9","  1","  66-85",2009,
"畠山士,西尾広介,中村光裕,坂本聡,関口健司,羽生尚広,加部泰明,和田忠士,半田宏","アフィニティ精製用担体としての高分子微粒子","第56回高分子学会年次大会","社団法人高分子学会",,"Vol. 56",,"pp. 3Pc149",2007,May
"畠山士,西尾広介,中村光裕,坂本聡,加部泰明,和田忠士,半田宏","アフィニティ精製用担体としての高分子微粒子",,"社団法人高分子学会、高分子論文集",,"Vol. 64","No. 1","pp. 9-20",2007,Jan.
"畠山士,加部泰明,半田宏","『ナノ粒子分散系の科学と技術』シーエムシー出版・医薬品分野における分散技術",,,"シーエムシー出版",,,"pp. 295-307",2006,Dec.
"川　和紀,嶋津　隆一,畠山　士,阿部　正紀,半田　宏,松下　伸広,吉村　昌弘","水熱法で成長させたフェライト粒子のポリマー被覆と磁気特性","粉体粉末冶金協会　平成18年度秋季大会","粉体粉末冶金協会",,,,"pp. 1-41B",2006,Dec.
"西尾広介,政池由佳,郷右近展之,壷内信吾,池田森人,成松宏樹,畠山士,坂本聡,阿部正紀,半田宏","ナノ磁性アフィニティビーズの構築","第14回高分子ミクロスフェア討論会","高分子ミクロスフェア討論会編集委員会",,"Vol. 14",,"pp. 145-146",2006,Nov.
"K. Nishio,Y. Masaike,N. Gokon,S. Tsubouchi,M. Ikeda,H. Narimatsu,M. Hatakeyama,S. Sakamoto,N. Hanyu,M. Abe,H. Handa.","Development of Novel Magnetic Nanobeads for Bio-Screening","The 3rd Asia Forum on Magnetics","The Magnetics Society of Japan",,"Vol. 30",,"pp. 485-486",2006,Sept.
"Hitoshi Uga,Chikanori Kuramori,Akiko Ohta,Yasunori Tsuboi,Hiroshi Tanaka,Mamoru Hatakeyama,Yuki Yamaguchi,Masahiro Kizaki,Takashi Takahashi,Hiroshi Handa","A new mechanism of methotrexate action revealed by target screening with affinity beads",,"Mol. Pharmacol.",,"Vol. 70","No. 5","pp. 1832-1839",2006,Aug.
"M. Hasegawa,H. Ohno,H. Tanaka,M. Hatakeyama,H. Kawaguchi,T. Takahashi,H. Handa","Affinity identification of δ-opioid receptors using latex particles.",,"Bioorganic & Medicinal Chemistry Letters",,"Vol. 16",,"pp. 158-161",2006,
"H. Uga,C. Kuramori,A. Ohta,Y. Tsuboi,H. Tanaka,M. Hatakeyama,Y. Yamaguchi,T. Takahashi,M. Kizaki,H. Handa.","A New Mechanism of Methotrexate Action Revealed by Target Screening with Affinity Beads",,"MOLECULAR PHARMACOLOGY",,"Vol. 70","No. 5","pp. 1832-1839",2006,
"S. Ohba,M. Hatakeyama,H. Handa,H. Kawaguchi","Development of Polymer Latex Particles for Selective Cleavage of Mismatched DNA and Their Application for DNA Diagnosis.",,"Bioconjugate Chemistry",,"Vol. 16",,"pp. 551-558",2005,
"Y. Ohtsu,R. Ohba,Y. Imamura,M. Kobayashi,H. Hatori,T. Zenkoh,M. Hatakeyama,T. Manabe,M. Hino,Y. Yamaguchi,K. Kataoka,H. Kawaguchi,H. Watanabe,H. Handa","Selective ligand purification using high-performance affinity beads.",,"Analytical Biochemistry",,"Vol. 338",,"pp. 245-252",2005,
"Tatsuya Zenkoh,Hidetaka Hatori,Hiroshi Tanaka,Makoto Hasegawa,Mamoru Hatakeyama,Yasuaki Kabe,Hiroyuki Setoi,Haruma Kawaguchi,Hiroshi Handa,Takashi Takashi","Design and Synthesis of a Solid-Supported FR225659 Derivative for Its Receptor Screening",,"Organic Letters",,"Vol. 6",,"pp. 2477-2480",2004,June
"S. Tsubouchi,K. Nishio,M. Ikeda,H. Narimatsu,M. Hatakeyama,N.Gokon,H. Handa","Polymer coating of ferrite nanoparticles by using “connector” chemical compounds.","International Conference on Ferrites (ICF-9), 9th","International Conference on Ferrites (ICF-9)",,,,"pp. 449-454",2004,
"田中浩士,善光龍哉,羽鳥英孝,小林幹央,長谷川慎,畠山士,瀬戸井宏行,日野資弘,川口春馬,半田　宏,高橋孝志","糖新生阻害剤FR225659のライブラリー構築とその標的蛋白質の探索","第19回Combinatorial Chemistry研究会","Combinatorial Chemistry研究会",,"Vol. 19",,"pp. O-10",2004,
"畠山士,加部泰明,半田宏","ナノテクノロジーによる薬物レセプター探索",,"Drug Delivery System",,"Vol. 19","No. 2","pp. 127-132",2004,
"K. Nishio,M. Hasegawa,M. Ikeda,H. Narimatsu,Y. Hase,Y.　Ogura,N.　Gokon,S.　Tsubouchi,M.　Hatakeyama,M.Abe,H.　Handa","Synthesis　of　monodisperse　ferrite nanoparticles　coated　with　polyacrylic acid (PAA).",,"Transactions of the Materials Research Society of Japan",,"Vol. 29",,"pp. 1659-1662",2004,
"加部泰明,畠山士,半田宏","新規アフィニティービーズの構築とその応用",,"化学工業、化学工業社",,"Vol. 54",,"pp. 50-55",2003,
"大場慎介,畠山士,半田宏,川口春馬","アフィニティラテックスを用いたミスマッチDNA識別","第24回日本バイオマテリアル学会","日本バイオマテリアル学会",,"Vol. 24",,"pp. 219",2002,Nov.
"T. Tomohiro,J. Sawada,C. Sawa,H. Nakura,S. Yoshida,M. Kodaka,M. Hatakeyama,H. Kawaguchi,H. Handa,H. Okuno","Total Analysis and Purification of Cellular Proteins Binding to Cisplatin-Damaged DNA Using Submicron Beads.",,"Bioconjugate Chemistry",,"Vol. 13",,"pp. 162-166",2002,
"M. Hiramoto,N. Shimizu,T. Nishi,D. Shima,S. Aizawa,H. Tanaka,M. Hatakeyama,H. Kawaguchi,H. Handa","High-performance affinity beads for identifying anti-NF-kappa-B drug receptors.",,"Methods in Enzymology",,"Vol. 353",,"pp. 81-88",2002,
"涌井渉,畠山士,永井康彦,七里徳重,川口春馬","磁性体微粒子のその場生成をともなう重合による複合粒子の作製","第50回高分子年次大会","高分子学会",,"Vol. 3",,"pp. 645",2001,May
"K. Kobayashi,M. Hatakeyama,Y. Toshima,Y. Tamada","Response by bylayer membranes containing the labial palpus of fly to stimulative substances.",,"Molecular Crystals and Liquid Crystals",,"Vol. 370",,"pp. 347-352",2001,
"小林一稔,畠山士,都島良行,玉田靖","ハエの舌弁組織を含有したリポソームの刺激応答評価","第49回高分子討論会","高分子学会",,"Vol. 13",,"pp. 4218-4219",2000,Sept.
"吉宗亜弓,畠山士,藤本啓二,半田宏,川口春馬","アフィニティラテックスにおけるポリエチレングリコール系スペーサーの検討","第49回高分子年次大会","高分子年次大会",,"Vol. 5",,"pp. 976",2000,May
"N. Shimizu,K. Sugimoto,J. Tang,T. Nishi,I. Sato,M. Hiramoto,S. Aizawa,M. Hatakeyama,R. Ohba,H. Hatori,T. Yoshikawa,F. Suzuki,A. Oomori,H. Tanaka,H. Kawaguchi,H. Watanabe,H. Handa","High-performance affinity beads for identifying drug receptors.",,"Nature Biotechnology",,"Vol. 18",,"pp. 877-881",2000,
"M. Hatakeyama,S. Iwato,K. Hanashita,K. Nakamura,K. Fujimoto,H. Kawaguchi","DNA-carrying latex particles 3. Detection of point mutant DNA using an indirect labeled probe.",,"Colloids and Surfaces A: Physicochemical and Engineering Aspects",,"Vol. 153",,"pp. 445-451",1999,
"M. Hatakeyama,K. Nakamura,K. Hanashita,H. Handa,K. Fujimoto,H. Kawaguchi","Development of DNA affinity latex for genetic diagnosis.","The 4th Asian Symposium on Biomedical Materials","The 4th Asian Symposium on Biomedical Materials",,,,"pp. 117",1999,
"中村恭子,畠山士,藤本啓二,川口春馬","DNA固定ラテックスとS1ヌクレアーゼを用いた点変異DNAの識別","第47回高分子討論会","高分子学会",,"Vol. 12",,"pp. 3074-3075",1998,Sept.
"畠山士,中村恭子,花下香子,藤本啓二,半田宏,川口春馬","遺伝子診断のためのDNAアフィニティラテックスの改良","第47回高分子年次大会","高分子学会",,"Vol. 4",,"pp. 805",1998,May
"畠山士","高分子ミクロスフェアを用いたアフィニティ分離と遺伝子診断への応用",,,,,,,1998,Mar.
"M. Hatakeyama,Y. Ogura,J. Sawada,K. Fujimoto,H. Handa,K. Kawaguchi","Preparation of dimerized polypeptide-carrying microspheres and purification of specific proteins bound to these micorspheres.",,"Colloids and Surfaces B: Biointerfaces",,"Vol. 10",,"pp. 41-49",1998,
"M. Hatakeyama,K. Nakamura,S. Iwato,H. Handa,K. Fujimoto,H. Kawaguchi","DNA-carrying latex particles 2. Distinction of normal and point mutant DNA using S1 nuclease.",,"Colloids and Surfaces B: Biointerfaces",,"Vol. 10",,"pp. 171-178",1998,
"M. Hatakeyama,S. Iwato,K. Fujimoto,H. Handa,H. Kawaguchi","DNA-carrying latex particles 1. Separation of normal and point mutant DNAs according to the difference in hybridization efficiency.",,"Colloids and Surfaces B: Biointerfaces",,"Vol. 10",,"pp. 161-169",1998,
"畠山士,岩戸聡子,中村恭子,藤本啓二,半田宏,川口春馬","DNA固定ラテックス粒子上での点変異遺伝子の識別","第46回高分子討論会","高分子学会",,"Vol. 12",,"pp. 3096-3097",1997,Sept.
"畠山士,岩戸聡子,中村恭子,藤本啓二,半田宏,川口春馬","高分子ミクロスフェアを用いた点変異DNAの識別","第7回バイオ・高分子シンポジウム","高分子学会",,"Vol. 7",,"pp. 5-6",1997,July
"畠山士,中村恭子,岩戸聡子,藤本啓二,半田宏,川口春馬","DNA一本鎖切断酵素を用いた遺伝子システムの構築","第46回高分子年次大会","高分子学会",,"Vol. 3",,"pp. 215",1997,May
"岩戸聡子,畠山士,藤本啓二,半田宏,川口春馬","DNA固定ラテックスを用いた点変異検出システムの構築","第46回高分子年次大会","高分子学会",,"Vol. 3",,"pp. 215",1997,May
"H. Kawaguchi,M. Hatakeyama,S. Iwato,K.Fujimoto,H. Handa","Affinity latex for DNA diagnosis.",,"Advances in Polymeric Biomaterials Science",,"Vol. 34",,"pp. 355-362",1997,
"M. Hatakeyama,H. Handa,K. Fujimoto,H. Kawaguchi","Preparation of dimerized polypeptide-carrying microspheres and purification of specific protein bound to these microspheres.","The 3rd Far-Eastern Symposium on Biomedical Materials","The 3rd Far-Eastern Symposium on Biomedical Materials",,,,"pp. 66-67",1997,
"M. Hatakeyama,S. Iwato,K. Nakamura,K. Fujimoto,H. Kawaguchi","Affinity latex for DNA diagnosis.","7th Iketani conference, International symposium on advanced technology of fine particles","7th Iketani conference, International symposium on advanced technology of fine particles",,,,"pp. 148",1997,
"岩戸聡子,畠山士,藤本啓二,半田宏,川口春馬","DNA固定ラテックスを用いた点変異検出システムの構築","第9回高分子ミクロスフェア討論会","高分子ミクロスフェア討論会編集委員会",,"Vol. 9",,"pp. 129-132",1996,Nov.
"畠山士,小倉豊,澤田潤一,後藤正英,藤本啓二,半田宏,川口春馬","ミクロスフェア表面へのポリペプチド鎖への固定化とアフィニティ活性","第45回高分子年次大会","高分子学会",,"Vol. 4",,"pp. 534",1996,May
"T. Imai,Y. Sumi,M. Hatakeyama,K. Fujimoto,H. Kawaguchi,N. Hayashida,K. Shiozaki,K. Terada,H. Yajima,H. Handa","Selective isolation of DNA and RNA using single-stranded DNA affinity latex particles.",,"Journal of Colloid and Interface Science",,"Vol. 177",,"pp. 245-249",1996,
"M. Hatakeyama,Y. Ogura,J. Sawada,M. Goto,K. Fujimoto,H. Handa,H. Kawaguchi","Preparation of polypeptide-carrying microspheres and their affinity activity.","36th IUPAC International Symposium on Macromolecules","36th IUPAC International Symposium on Macromolecules",,,,"pp. 490",1996,
"畠山士,今井剛,藤本啓二,半田宏,川口春馬","転写タンパク分離精製のためのいくつかのアフィニティラテックス","第7回MRS-Jシンポジウム","日本MRS学会",,,,"pp. 195",1995,Sept.
"畠山士,藤本啓二,半田宏,川口春馬","ラテックス粒子へのポリペプチドのハイブリッド化","第44回高分子年次大会","高分子学会",,"Vol. 3",,"pp. 407",1995,May
"M. Hatakeyama,Y. Ogura,J. Sawada,K. Fujimoto,H. Handa,H. Kawaguchi","Affinity separation by latex particles.","The Second Far-Eastern Symposium on Biomedical Materials","The Second Far-Eastern Symposium on Biomedical Materials",,,,"pp. 89",1995,
"T. Shiroya,M. Hatakeyama,K. Fujimoto,H. Watanabe,T. Wada,T. Imai,H. Kawaguchi,H. Handa","Purification of transcription factor IIA using yeast TATA-binding protein affinity latex particles.",,"International Journal of bio-chromatography",,"Vol. 1",,"pp. 191-198",1995,
"畠山士,白谷俊史,藤本啓二,半田宏,川口春馬","転写因子精製のためのアフィニティラテックス","第8回高分子ミクロスフェア討論会","高分子ミクロスフェア討論会編集委員会",,"Vol. 8",,"pp. 103-106",1994,Nov.