"山本淳一,山口雄輝,半田宏","レナリドマイド耐性多発性骨髄腫細胞の生存に重要なポマリドマイド依存性CRL4CRBNのネオ基質ARID2の解析","第45回日本分子生物学会",,,,,,2022,Dec. "Junichi Yamamoto,Tomoko Asatsuma-Okumura,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","History of IMiDs and Protein Degradation as a Pharmacological Modality",,"Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective","John Wiley & Sons",,,,2022,Nov. "Junichi Yamamoto,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders.",,"CHEM. SOC. REV.",," 51",," 6234-6250",2022,July "山本淳一","ポマリドミド依存的なCRLCRBNのネオ基質ARID2の解析","三重造血器腫瘍WEBセミナー",,,,,,2022,Mar. "山本淳一,山口雄輝,半田宏","ホ?マリト?ミト?依存的な CRBN のネオ基質 ARID2 の解析","第44回日本分子生物学会年会",,,,,,2021,Dec. "山本淳一,山口雄輝,半田宏","ポマリドミド依存的なCRBNのネオ基質ARID2の解析","第44回日本分子生物学会",,,,,,2021,Dec. "Nobuyuki Shimizu,Tomoko Asatsuma-Okumura,Junichi Yamamoto,Yuki Yamaguchi,Hiroshi Handa,Takumi Ito","PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates",,"Commun. Biol.",," 4"," 1"," 1277",2021,Nov. "山本淳一","ポマリドミドの新規作用機序の解明 ?新規創薬標的ARID2の発見?","BMS Myeloma Seminar",,,,,,2021,Oct. "Junichi Yamamoto,Tetsufumi Suwa,Yuki Murase,Shunpei Tateno,Hirotaka Mizutome,Tomoko Asatsuma-Okumura,Nobuyuki Shimizu,Tsutomu Kishi,Shuji Momose,Masahiro Kizaki,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells",,"Nature Chemical Biology",,,,,2020,Sept. "Shunpei Tateno,Midori Iida,Satoshi Fujii,Miki Katayama,Haruka Tokuyama,Junichi Yamamoto,Takumi Ito,Satoshi Sakamoto,Hiroshi Handa,Yuki Yamaguchi","Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide?",,"Scientific Reports",,"Volume 10","Number 4012",,2020,Mar. "Takahashi H,Ranjan A,Chen S,Suzuki H,Shibata M,Hirose T,Hirose H,Sasaki K,Abe R,Chen K,He Y,Zhang Y,Takigawa I,Tsukiyama T,Watanabe M,Fujii S,Iida M,Yamamoto J,Yamaguchi Y,Suzuki Y,Matsumoto M,Nakayama KI,Washburn MP,Saraf A,Florens L,Sato S,Tomomori-Sato C,Conaway RC,Conaway JW,Hatakeyama S","The role of Mediator and Little Elongation Complex in transcription termination",,"Nat Commun.",,"Vol. 11","No. 1","p. 1063",2020,Feb. "Asatsuma-Okumura T,Ando H,De Simone M,Yamamoto J,Sato T,Shimizu N,Asakawa K,Yamaguchi Y,Takumi Ito,Guerrini L,Hiroshi Handa","p63 is a cereblon substrate involved in thalidomide teratogenicity",,"Nature Chemical Biology",,," 15","Page 1077?1084",2019,Oct. "Ando, H.,Sato, T.,Ito, T.,Yamamoto, J.,Sakamoto, S.,Nitta, N.,Asatsuma-Okumura, T.,Shimizu, N.,Mizushima, R.,Aoki, I.,Imai, T.,Yamaguchi, Y.,Berk, A.J.,Hiroshi Handa","Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation",,"iScience",,,,,2019,Apr. "Fajar Muhamad,Ari Zukeran,Shunpei Tateno,Junichi Yamamoto,Hiroshi Handa,Yuki Yamaguchi","Mechanisms that affect post-transcriptional fate of RNA polymerase II-transcribed genes","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "高橋 秀尚,柴田 美音,瀧川 一学,渡部 昌,築山 忠維,山本 淳一,山口 雄輝,藤井聡,飯田緑,Amol Ranjan,Shigeo Sato,Chieri Tomomori-Sato,Joan Conaway,Ronald Conaway,畠山 鎮次","メディエーター複合体による転写終結制御機構","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "山本 淳一,Fajar Muhamad,瑞慶覧 安里,舘野 峻平,半田宏,山口 雄輝","NELFを中心としたポリ(A)付加部位の選択機構の解析","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "Shunpei Tateno,Ari Zukeran,Junichi Yamamoto,Yuki Yamaguchi","Molecular mechanisms for polyadenylation site selection by NELF and related factors","Mechanisms of Eukaryotic Transcription 2017",,,,,,2017,Aug. "瑞慶覧 安里,舘野 峻平,山本淳一,山口 雄輝","RNAポリメラーゼ?転写産物の長さを決める3’末端プロセシングの制御メカニズムの解明","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan. "瑞慶覧 安里,山本 淳一,山口 雄輝","How Pol II termination and 3' processing sites are precisely determined in higher eukaryotes.高等真核生物においてPol IIの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか","第39回日本分子生物学会年会",,,,,,2016,Nov. "瑞慶覧 安里,山本 淳一,山口 雄輝","NELFを中心としたポリ(A)付加部位選択のメカニズム","第39回日本分子生物学会年会",,,,,,2016,Nov. "瑞慶覧 安里,舘野 峻平,山本淳一,山口 雄輝","NELFを中心としたポリ(A)付加部位選択のメカニズム","新学術領域研究「転写サイクル」班会議2016",,,,,,2016,Sept. "瑞慶覧 安里,長谷川 冴妃子,舘野 峻平,山本淳一,山口 雄輝","高等真核生物においてPOL ?の転写終結と3'プロセシングの部位はいかにして正確に決定されるのか","新学術領域研究「転写サイクル」班会議2016",,,,,,2016,Sept. "伊藤 拓水,朝妻 知子,山本 淳一,安藤 秀樹,佐藤 智美,山口 雄輝,半田 宏","リガンド依存的ユビキチンリガーゼCRBNの制御機構","日本ケミカルバイオロジー学会第11回年会",,,,,,2016,June "山口 雄輝,伊藤拓水,山本淳一,半田宏","サリドマイドの多様な薬理作用の分子メカニズム","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb. "瑞慶覧 安里,山本 淳一,磯部 智康,山口 雄輝","NELFを中心としたRNAの品質管理のメカニズム","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb. "Qing-Fu Cao,Junichi Yamamoto,Tomoyasu Isobe,Shunpei Tateno,Yuki Murase,Yexi Chen,Hiroshi Handa,Yuki Yamaguchi","Characterization of the human transcription elongation factor Rtf1: evidence for non-overlapping functions of Rtf1 and the Paf1 complex",,"Mol. Cell. Biol.",,"Vol. 35","No. 20","pp. 3459-3470",2015,Oct. "Yuki Yamaguchi,Junichi Yamamoto","Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes","MECHANISM OF EUKARYOTIC TRANSCRIPTION",,,,,,2015,Aug. "Tatsuya Fukushima,Junichi Yamamoto,Masashi Fukuchi,Shuzo Hirata,Heo Hyo Jung,Osamu Hirata,Yuki Shibano,Chihaya Adachi,Hironori Kaji*","Material degradation of liquid organic semiconductors analyzed by nuclear magnetic resonance spectroscopy",,"AIP Advances",,"Vol. 5",,"pp. 087124",2015,Aug. "瑞慶覧 安里,山本 淳一,磯部智康,山口 雄輝","NELFを中心としたmRNAの品質管理のメカニズム","新学術領域研究「転写サイクル」班会議2015",,,,,,2015,Aug. "山口 雄輝,磯部智康,曹 青福,山本 淳一","転写伸長段階の制御メカニズム:新たな制御因子の探索","新学術領域研究「転写サイクル」班会議2015",,,,,,2015,Aug. "山本淳一,半田宏,山口 雄輝","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes","新学術領域研究「転写サイクル」冬の若手ワークショップ2015",,,,,,2015,Feb. "Yuki Yamaguchi,Junichi Yamamoto","Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes","新学術領域研究「転写サイクル」国際シンポジウム2014",,,,,,2014,Nov. "山本淳一","RNA ポリメラーゼII転写産物の3’末端プロセシング経路の運命決定機構に関する研究",,,,,,,2014,Sept. "山本淳一","RNA ポリメラーゼII転写産物の3’末端プロセシング経路の運命決定機構に関する研究",,,,,,,2014,Sept. "山本淳一","RNA ポリメラーゼII転写産物の3’末端プロセシング経路の運命決定機構に関する研究",,,,,,,2014,Sept. "山本淳一","RNA ポリメラーゼII転写産物の3’末端プロセシング経路の運命決定機構に関する研究",,,,,,,2014,Sept. "山本淳一,半田宏,山口雄輝","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug. "山口雄輝,山本淳一,半田宏","ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug. "Junichi Yamamoto,Yuri Hagiwara,Kunitoshi Chiba,Tomoyasu Isobe,Takashi Narita,Hiroshi Handa,Yuki Yamaguchi","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes.",,"Nat. Commun.",,"Vol. 5",,"pp. 4263",2014,June "Kunitoshi Chiba,Junichi Yamamoto,Yuki Yamaguchi,Hiroshi Handa","Promoter-proximal pausing and its release: molecular mechanisms and physiological functions",,"Exp. Cell Res.",,"Vol. 316","No. 17","p. 2723-2730",2010,Oct. "Sol Kim,Junichi Yamamoto,Yexi Chen,Masatoshi Aida,Tadashi Wada,Hiroshi Handa,Yuki Yamaguchi","Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation",,"Genes Cells",,"Vol. 15","No. 9","p. 1003-1013",2010,Sept. "Yexi Chen,Yuki Yamaguchi,Yuta Tsugeno,Junichi Yamamoto,Tomoko Yamada,Mitsuhiro Nakamura,Koji Hisatake,Hiroshi Handa","DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation",,"Genes Dev.",," 23"," 23"," 2765-2777",2009,Dec. "Takashi Narita,Yung, T.M.C.,Junichi Yamamoto,Tsuboi, Y.,Tanabe, H.,Tanaka, K.,Yamaguchi, Y.,HIROSHI HANDA,,","NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs",,"Mol. Cell",,"Vol. 26","No. 3","pp. 349-365",2007,May