"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","Size-regulated siRNA carriers from small complex loading single siRNA molecule for systemic delivery to tumor tissue","第77回日本癌学会学術総会",,,,,,2018,Sept.
"Y. Anraku,H. Kuwahara,Y. Fukusato,A. Mizoguchi,T. Ishii,K. Nitta,Y. Matsumoto,K. Toh,K. Miyata,S. Uchida,K. Nishina,K. Osada,K. Itaka,N. Nishiyama,H. Mizusawa,T. Yamasoba,T. Yokota,K. Kataoka","Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain",,"Nature Communications",,"Vol. 8",,"pp. 1001",2017,Oct.
"Mitsuru Naito,Ryota Azuma,Hiroyasu Takemoto,Mao Hori,Naoto Yoshinaga,Shigehito Osawa,Rimpei Kamegawa,Hyun Jin Kim,Takehiko Ishii,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori","Multilayered Polyion Complexes with Dissolvable Silica Layer Covered by Controlling Densities of cRGD-conjugated PEG Chains for Cancer-targeted siRNA Delivery",,"Journal of Biomaterials Science, Polymer Edition",,"Vol. 28",,"pp. 1109-1123",2017,Mar.
"武元宏泰,キム ヒュンジン,宮田完二郎,西山伸宏,片岡一則","単分子siRNA内包型小会合体を要素とするsiRNAキャリアの構築と全身投与による腫瘍組織への送達","日本薬学会第137年会",,,,,,2017,Mar.
"C. Moriya,H. Taniguchi,K. Miyata,N. Nishiyama,K. Kataoka,K. Imai","Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice",,"Carcinogenesis",,"Vol. 38","No. 6","pp. 638-648",2017,Jan.
"越後真梨那,武元 宏泰,林 光太朗,宮田 完二郎,金澤秀子,片岡 一則,西山 伸宏","がん細胞内にて特異的に切断される Linker を利用した siRNA 送達キャリアの開発","日本バイオマテリアル学会シンポジウム 2016",,,,,,2016,Nov.
"武元宏泰,宮田完二郎,林光太朗,持田祐希,片岡一則,西山伸宏","シロキサンネットワークにて形成されるsiRNA内包有機-無機ハイブリッドナノ粒子の開発","日本バイオマテリアル学会シンポジウム 2016",,,,,,2016,Nov.
"Yi Yu,Hyun Jin Kim,Peng Mi,Meng Zheng,Hiroyasu Takemoto,Kazuko Toh,Kim Beob Soo,Kotaro Hayashi,Mitsuru Naito,Yu Matsumoto,Kanjiro Miyata,Kazunori Kataoka","Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.",,"Journal of Controlled Release","Elsevier",,,,2016,Sept.
"Haruka Nishida,Yoko Matsumoto,Kei Kawana,Christie James,Mitsuru Naito,Kim Beob Soo,Kazuko Toh,Hyun Su Min,Yi Yu,Yu Mastumoto,Hyun Jin Kim,Kanjiro Miyata,Ayumi Taguchi,Kensuke Tomio,Aki Yamashita,Tomoko Inoue,Hiroe Nakamura,Asaha Fujimoto,Masakazu Sato,Mitsuyo Yoshida,Katsuyuki Adachi,Takahide Arimoto,Osamu Wada-Hiraike,Katsutoshi Oda,Takeshi Nagamatsu,Nobuhiro Nishiyama,Kazunori Kataoka,Yutaka Osuga,Tomoyuki Fujii","Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes",,"Journal of Controlled Release",,"Vol. 231",,"pp. 29-37",2016,Mar.
"Hirokuni Uchida,Keiji Itaka,Satoshi Uchida,Takehiko Ishii,Tomoya Suma,Kanjiro Miyata,Makoto Oba,Nobuhiro Nishiyama,Kazunori Kataoka","Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure",,"Journal of the American Chemical Society",,"Vol. 138","No. 5","pp. 1478-1481",2016,Jan.
"Kotaro Hayashi,Hiroyuki Chaya,Shigeto Fukushima,Sumiyo Watanabe,Hiroyasu Takemoto,Kensuke Osada,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers",,"Macromolecular Rapid Communications",,"Vol. 37","No. 6","pp. 486-493",2016,Jan.
"Kotaro Hayashi,Hiroyuki Chaya,Shigeto Fukushima,Sumiyo Watanabe,Hiroyasu Takemoto,Kensuke Osada,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Macromol. Rapid Commun. 6/2016.",,"Macromolecular rapid communications",,"Vol. 37","No. 6","pp. 560",2016,Jan.
"Takahiro Nomoto,Shigeto Fukushima,Michiaki Kumagai,Kaori Machitani,Kanjiro Miyata,Makoto Oba,Yu Matsumoto,Kensuke Osada,Nobuhiro Nishiyama,Kazunori Kataoka","Three-layered polyplex micelle for light-induced gene transfer","The 13th US-Japan DDS symposium",,,,,,2015,Dec.
"Masahiro Murakami,Kazutaka Nishina,Chie Watanabe,Kie Yoshida-Tanaka,Wenying Piao,Hiroya Kuwahara,Yuji Horikiri,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka,Masayuki Yoshida,Hidehiro Mizusawa,Takanori Yokota","Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route",,"Scientific Reports",,"Vol. 5",,,2015,Nov.
"Hui Gao,Hiroyasu Takemoto,Qixian Chen,Mitsuru Naito,Hirokuni Uchida,Xueying Liu,Kanjiro Miyata,Kazunori Kataoka","Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity",,"Chemical Communications",,"Vol. 51","No. 15","pp. 3158-3161",2015,
"Meng Zheng,Hyun Jin Kim,Hiroyasu Takemoto,Kanjiro Miyata,Kazunori Kataoka","Precisely regulated nanoarchitecture comprised of gold nanotemplate and unimer polyion complex for systemic delivery of siRNA",,"Journal of Controlled Release",,"Vol. 213",,"pp. E75-E76",2015,
"Yoshinori Maeda,Frederico Pittella,Takahiro Nomoto,Hiroyasu Takemoto,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles",,"Macromolecular Rapid Communications",,"Vol. 35","No. 13","pp. 1211-1215",2014,
"Frederico Pittella,Cabral Horacio,Yoshinori Maeda,Peng Mi,Sumiyo Watanabe,Hiroyasu Takemoto,Hyun Jin Kim,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles",,"Journal of Controlled Release",,"Vol. 178",,"pp. 18-24",2014,
"Hyun Jin Kim,Hiroyasu Takemoto,Yi Yu,Meng Zheng,Yoshinori Maeda,Hiroyuki Chaya,Kotaro Hayashi,Peng Mi,Frederico Pittella,Christie James,Kazuko Toh,Yu Mastumoto,Nobuhiro Nishiyama,Kanjiro Miyata,Kazunori Kataoka","Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles",,"Acs Nano",,"Vol. 8","No. 9","pp. 8979-8991",2014,
"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","Bioresponsive Polymer-Based Nucleic Acid Carriers",,"Nonviral Vectors For Gene Therapy Lipid- and Polymer-Based Gene Transfer",,"Vol. 88",,"pp. 289-323",2014,
"Hiroyasu Takemoto,Kanjiro Miyata,Shota Hattori,Takehiko Ishii,Tomoya Suma,Satoshi Uchida,Nobuhiro Nishiyama,Kazunori Kataoka","Acidic pH-Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosomal Escape with Reduced IFN alpha-Associated Immune Response",,"Angewandte Chemie-International Edition",,"Vol. 52","No. 24","pp. 6218-6221",2013,
"武元宏泰,宮田完二郎","生体内還元環境とそれに応答する薬剤キャリア設計",,"遺伝子医学MOOK別冊 ここまで広がるドラッグ徐放技術の最前線 古くて新しいドラッグデリバリーシステム",,,,"  351-356",2013,
"Kanjiro Miyata,Christie James,Tomoya Suma,Hiroyasu Takemoto,Hirokuni Uchida,Nobuhiro Nishiyama,Kazunori Kataoka","Fine-Tuning of Repeating Aminoethyelene Units in Poly(aspartamide) Side Chains for Enhanced siRNA Delivery",,"Tailored Polymer Architectures For Pharmaceutical and Biomedical Applications",,"Vol. 1135",,"pp. 189-196",2013,
"Tomoya Suma,Kanjiro Miyata,Yasutaka Anraku,Sumiyo Watanabe,Christie James,Hiroyasu Takemoto,Momoko Shioyama,Noha Gouda,Takehiko Ishii,Nobuhiro Nishiyama,Kazunori Kataoka","Smart Multilayered Assembly for Biocompatible siRNA Delivery Featuring Dissolvable Silica, Endosome-Disrupting Polycation, and Detachable PEG",,"Acs Nano",,"Vol. 6","No. 8","pp. 6693-6705",2012,
"Hiroyasu Takemoto,Kanjiro Miyata,Nobuhiro Nishiyama,Kazunori Kataoka","siRNA-grafted polymer for efficient siRNA delivery system",,"Abstracts of Papers of the American Chemical Society",,"Vol. 243",,,2012,
"Hiroyasu Takemoto,Kanjiro Miyata,Takehiko Ishii,Shota Hattori,Shigehito Osawa,Nobuhiro Nishiyama,Kazunori Kataoka","Accelerated Polymer-Polymer Click Conjugation by Freeze-Thaw Treatment",,"Bioconjugate Chemistry",,"Vol. 23","No. 8","pp. 1503-1506",2012,
"Hiroyasu Takemoto,Atsushi Ishii,Kanjiro Miyata,Masataka Nakanishi,Makoto Oba,Takehiko Ishii,Yuichi Yamasaki,Nobuhiro Nishiyama,Kazunori Kataoka","Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system",,"Biomaterials",,"Vol. 31","No. 31","pp. 8097-8105",2010,
"Kanjiro Miyata,Noha Gouda,Hiroyasu Takemoto,Makoto Oba,Yan Lee,Hiroyuki Koyama,Yuichi Yamasaki,Keiji Itaka,Nobuhiro Nishiyama,Kazunori Kataoka","Enhanced transfection with silica-coated polyplexes loading plasmid DNA",,"Biomaterials",,"Vol. 31","No. 17","pp. 4764-4770",2010,
"Kanjiro Miyata,Takahiro Nomoto,Hiroyasu Takemoto,Hyun Jin Kim,Yu Matsumoto,Makoto Oba,Nobuhiro Nishiyama,Kazunori Kataoka","Development of advanced polymer-based nanodevices for nucleic acids delivery",,"Abstracts of Papers of the American Chemical Society",,"Vol. 240",,,2010,