"Zhang, Y.,Watanabe, S.,Tsutsumi, A.,Kadokura, H.,Kikkawa, M.,Inaba, K.,Hiroshi Kadokura","Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca<sup>2+</sup>-ATPase SERCA2b",,"EMBO Journal",,"Vol. 40","No. 19",,2021,
"Kanemura, S.,Sofia, E.F.,Hirai, N.,Okumura, M.,Kadokura, H.,Inaba, K.,Hiroshi Kadokura","Characterization of the endoplasmic reticulum?resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding",,"Journal of Biological Chemistry",,"Vol. 295","No. 36","pp. 12772-12785",2020,
"Kadokura, H.,Dazai, Y.,Fukuda, Y.,Hirai, N.,Nakamura, O.,Inaba, K.,Hiroshi Kadokura","Observing the nonvectorial yet cotranslational folding of a multidomain protein, LDL receptor, in the ER of mammalian cells",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 117","No. 28","pp. 16401-16408",2020,
"Fujimoto, T.,Inaba, K.,Kadokura, H.,Hiroshi Kadokura","Methods to identify the substrates of thiol-disulfide oxidoreductases",,"Protein Science",,"Vol. 28","No. 1","pp. 30-40",2019,
"Fujimoto, T.,Nakamura, O.,Saito, M.,Tsuru, A.,Matsumoto, M.,Kohno, K.,Inaba, K.,Kadokura, H.,Hiroshi Kadokura","Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member",,"Journal of Biological Chemistry",,"Vol. 293","No. 48","pp. 18421-18433",2018,
"Tsuchiya, Y.,Saito, M.,Kadokura, H.,Miyazaki, J.,Tashiro, F.,Imagawa, Y.,Iwawaki, T.,Kohno, K.,Hiroshi Kadokura","IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic ƒÀ cells",,"Journal of Cell Biology",,"Vol. 217","No. 4","pp. 1287-1301",2018,
"Okumura, M.,Kadokura, H.,Inaba, K.,Hiroshi Kadokura","Structures and functions of protein disulfide isomerase family members involved in proteostasis in the endoplasmic reticulum",,"Free Radical Biology and Medicine",,"Vol. 83",,"pp. 314-322",2015,
"Okumura, M.,Kadokura, H.,Hashimoto, S.,Yutani, K.,Kanemura, S.,Hikima, T.,Hidaka, Y.,Ito, L.,Shiba, K.,Masui, S.,Imai, D.,Imaoka, S.,Yamaguchi, H.,Inaba, K.,Hiroshi Kadokura","Inhibition of the functional interplay between endoplasmic reticulum (ER) Oxidoreduclin-1ƒ¿ (Ero1ƒ¿) and protein-disulfide isomerase (PDI) by the endocrine disruptor bisphenol A",,"Journal of Biological Chemistry",,"Vol. 289","No. 39","pp. 27004-27018",2014,
"Tsuru, A.,Fujimoto, N.,Takahashi, S.,Saito, M.,Nakamura, D.,Iwano, M.,Iwawaki, T.,Kadokura, H.,Ron, D.,Kohno, K.,Hiroshi Kadokura","Negative feedback by IRE1ƒÀ optimizes mucin production in goblet cells",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 110","No. 8","pp. 2864-2869",2013,
"Kadokura, H.,Saito, M.,Tsuru, A.,Hosoda, A.,Iwawaki, T.,Inaba, K.,Kohno, K.,Hiroshi Kadokura","Identification of the redox partners of ERdj5/JPDI, a PDI family member, from an animal tissue",,"Biochemical and Biophysical Research Communications",,"Vol. 440","No. 2","pp. 245-250",2013,
"Nakayashiki, T.,Saito, N.,Takeuchi, R.,Kadokura, H.,Nakahigashi, K.,Wanner, B.L.,Mori, H.,Hiroshi Kadokura","The tRNA thiolation pathway modulates the intracellular redox state in Escherichia coli",,"Journal of Bacteriology",,"Vol. 195","No. 9","pp. 2039-2049",2013,
"Chng, S.-S.,Xue, M.,Garner, R.A.,Kadokura, H.,Boyd, D.,Beckwith, J.,Kahne, D.,Hiroshi Kadokura","Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export",,"Science",,"Vol. 337","No. 6102","pp. 1665-1668",2012,
"Sopha, P.,Kadokura, H.,Yamamoto, Y.H.,Takeuchi, M.,Saito, M.,Tsuru, A.,Kohno, K.,Hiroshi Kadokura","A novel mammalian ER-located J-protein, DNAJB14, can accelerate ERAD of misfolded membrane proteins.",,"Cell structure and function",,"Vol. 37","No. 2","pp. 177-187",2012,
"Chng, S.-S.,Dutton, R.J.,Denoncin, K.,Vertommen, D.,Collet, J.-F.,Kadokura, H.,Beckwith, J.,Hiroshi Kadokura","Overexpression of the rhodanese PspE, a single cysteine-containing protein, restores disulphide bond formation to an Escherichia coli strain lacking DsbA",,"Molecular Microbiology",,"Vol. 85","No. 5","pp. 996-1006",2012,
"Shinya, S.,Kadokura, H.,Imagawa, Y.,Inoue, M.,Yanagitani, K.,Kohno, K.,Hiroshi Kadokura","Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro",,"Nucleic Acids Research",,"Vol. 39","No. 12","pp. 5245-5254",2011,
"Yanagitani, K.,Kimata, Y.,Kadokura, H.,Kohno, K.,Hiroshi Kadokura","Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA",,"Science",,"Vol. 331","No. 6017","pp. 586-589",2011,
"Kadokura, H.,Beckwith, J.,Hiroshi Kadokura","Mechanisms of oxidative protein folding in the bacterial cell envelope",,"Antioxidants and Redox Signaling",,"Vol. 13","No. 8","pp. 1231-1246",2010,
"Yamamoto, Y.H.,Kimura, T.,Momohara, S.,Takeuchi, M.,Tani, T.,Kimata, Y.,Kadokura, H.,Kohno, K.,Hiroshi Kadokura","A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR.",,"Cell structure and function",,"Vol. 35","No. 2","pp. 107-116",2010,
"Ohtsu, I.,Wiriyathanawudhiwong, N.,Morigasaki, S.,Nakatani, T.,Kadokura, H.,Takagi, H.,Hiroshi Kadokura","The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in Escherichia coli",,"Journal of Biological Chemistry",,"Vol. 285","No. 23","pp. 17479-17487",2010,
"Eser, M.,Masip, L.,Kadokura, H.,Georgiou, G.,Beckwith, J.,Hiroshi Kadokura","Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 106","No. 5","pp. 1572-1577",2009,
"Kadokura, H.,Beckwith, J.,Hiroshi Kadokura","Detecting Folding Intermediates of a Protein as It Passes through the Bacterial Translocation Channel",,"Cell",,"Vol. 138","No. 6","pp. 1164-1173",2009,
"Zhou, Y.,Cierpicki, T.,Jimenez, R.H.F.,Lukasik, S.M.,Ellena, J.F.,Cafiso, D.S.,Kadokura, H.,Beckwith, J.,Bushweller, J.H.,Hiroshi Kadokura","NMR Solution Structure of the Integral Membrane Enzyme DsbB: Functional Insights into DsbB-Catalyzed Disulfide Bond Formation",,"Molecular Cell",,"Vol. 31","No. 6","pp. 896-908",2008,
"Segatori, L.,Murphy, L.,Arredondo, S.,Kadokura, H.,Gilbert, H.,Beckwith, J.,Georgiou, G.,Hiroshi Kadokura","Conserved role of the linker ƒ¿-helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB",,"Journal of Biological Chemistry",,"Vol. 281","No. 8","pp. 4911-4919",2006,
"Kadokura, H.,Hiroshi Kadokura","Oxidative protein folding: Many different ways to introduce bisulfide bonds",,"Antioxidants and Redox Signaling",,"Vol. 8","No. 5-6","pp. 731-733",2006,
"Sevier, C.S.,Kadokura, H.,Tam, V.C.,Beckwith, J.,Fass, D.,Kaiser, C.A.,Hiroshi Kadokura","The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases",,"Protein Science",,"Vol. 14","No. 6","pp. 1630-1642",2005,
"Kadokura, H.,Nichols II, L.,Beckwith, J.,Hiroshi Kadokura","Mutational alterations of the key cis proline residue that cause accumulation of enzymatic reaction intermediates of DsbA, a member of the thioredoxin superfamily",,"Journal of Bacteriology",,"Vol. 187","No. 4","pp. 1519-1522",2005,
"Kadokura, H.,Tian, H.,Zander, T.,Bardwell, J.C.A.,Beckwith, J.,Hiroshi Kadokura","Snapshots of DsbA in Action: Detection of Proteins in the Process of Oxidative Folding",,"Science",,"Vol. 303","No. 5657","pp. 534-537",2004,
"Kadokura, H.,Katzen, F.,Beckwith, J.,Hiroshi Kadokura","Protein disulfide bond formation in prokaryotes",,"Annual Review of Biochemistry",,"Vol. 72",,"pp. 111-135",2003,
"Kadokura, H.,Hiroshi Kadokura","Protein disulfide bond formation in vivo",,"Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme",,"Vol. 48","No. 10","pp. 1386-1393",2003,
"Kadokura, H.,Beckwith, J.,Hiroshi Kadokura","Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA",,"EMBO Journal",,"Vol. 21","No. 10","pp. 2354-2363",2002,
"Suzuki, K.,Sami, M.,Kadokura, H.,Nakajima, H.,Kitamoto, K.,Hiroshi Kadokura","Biochemical characterization of horA-independent hop resistance mechanism in Lactobacillus brevis",,"International Journal of Food Microbiology",,"Vol. 76","No. 3","pp. 223-230",2002,
"Kadokura, H.,Kawasaki, H.,Yoda, K.,Yamasaki, M.,Kitamoto, K.,Hiroshi Kadokura","Efficient export of alkaline phosphatase overexpressed from a multicopy plasmid requires degP, a gene encoding a periplasmic protease of Escherichia coli",,"Journal of General and Applied Microbiology",,"Vol. 47","No. 3","pp. 133-141",2001,
"Xu, X.Y.,Kadokura, H.,Okubo, A.,Kitamoto, K.,Yamazaki, S.,Hiroshi Kadokura","Cloning and sequencing of a gene encoding a novel salt stress-induced membrane protein from Rhodobacter sphaeroides f. sp. denitrificans",,"Applied Microbiology and Biotechnology",,"Vol. 56","No. 3-4","pp. 442-447",2001,
"Kadokura, H.,Beckwith, J.,Hiroshi Kadokura","The expanding world of oxidative protein folding",,"Nature Cell Biology",,"Vol. 3","No. 11","pp. E247-E249",2001,
"Kadokura, H.,Bader, M.,Tian, H.,Bardwell, J.C.A.,Beckwith, J.,Hiroshi Kadokura","Roles of a conserved arginine residue of DsbB in linking protein disulfide-bond-formation pathway to the respiratory chain of Escherichia coli",,"Proceedings of the National Academy of Sciences of the United States of America",,"Vol. 97","No. 20","pp. 10884-10889",2000,
"Maruyama, J.-I.,Ohnuma, H.,Yoshikawa, A.,Kadokura, H.,Nakajima, H.,Kitamoto, K.,Hiroshi Kadokura","Production and product quality assessment of human hepatitis B virus pre-S2 antigen in submerged and solid-state cultures of Aspergillus oryzae",,"Journal of Bioscience and Bioengineering",,"Vol. 90","No. 1","pp. 118-120",2000,
"Haruta, M.,Murata, M.,Kadokura, H.,Homma, S.,Hiroshi Kadokura","Immunological and molecular comparison of polyphenol oxidase in Rosaceae fruit trees",,"Phytochemistry",,"Vol. 50","No. 6","pp. 1021-1025",1999,
"Haruta, M.,Murata, M.,Hiraide, A.,Kadokura, H.,Yamasaki, M.,Sakuta, M.,Shimizu, S.,Kadokura, H.,Hiroshi Kadokura","Cloning genomic dna encoding apple polyphenol oxidase and comparison of the gene product in escherichia coli and in apple",,"Bioscience, Biotechnology and Biochemistry",,"Vol. 62","No. 2","pp. 358-362",1998,
"Sami, M.,Suzuki, K.,Sakamoto, K.,Kadokura, H.,Kitamoto, K.,Yoda, K.,Hiroshi Kadokura","A plasmid pRH45 of Lactobacillus brevis confers hop resistance",,"Journal of General and Applied Microbiology",,"Vol. 44","No. 5","pp. 361-363",1998,
"Wang, T.,Kadokura, H.,Yada, K.,Yamasaki, M.,Hiroshi Kadokura","Identification of a sulfhydryl-reducing agent-inducible protein highly homologous to protein synthesis elongation factor Tu in Bacillus subtilis",,"Wei sheng wu xue bao = Acta microbiologica Sinica",,"Vol. 38","No. 1","pp. 6-12",1998,
"Sami, M.,Yamashita, H.,Kadokura, H.,Kitamoto, K.,Yoda, K.,Yamasaki, M.,Hiroshi Kadokura","A new and rapid method for determination of beer-spoilage ability of lactobacilli",,"Journal of the American Society of Brewing Chemists",,"Vol. 55","No. 4","pp. 137-140",1997,
"Sami, M.,Yamashita, H.,Hirono, T.,Kadokura, H.,Kitamoto, K.,Yoda, K.,Yamasaki, M.,Hiroshi Kadokura","Hop-resistant Lactobacillus brevis contains a novel plasmid harboring a multidrug resistance-like gene",,"Journal of Fermentation and Bioengineering",,"Vol. 84","No. 1","pp. 1-6",1997,
"Wang, T.,Hiroshi, K.,Makari, Y.,Hiroshi Kadokura","Identification of a disulfide bonded protein from cytoplasm of Bacillus subtilis",,"Chinese Science Bulletin",,"Vol. 42","No. 20","pp. 1756-1760",1997,
"Wang, T.,Kadokura, H.,Yoda, K.,Yamasaki, M.,Hiroshi Kadokura","Internal amino acid sequence analysis of proteins after limited proteolytic cleavage",,"Progress in Biochemistry and Biophysics",,"Vol. 24","No. 1","pp. 68-71",1997,
"Chang, Y.-C.,Kadokura, H.,Yoda, K.,Yamasaki, M.,Hiroshi Kadokura","Secretion of active subtilisin YaB by a simultaneous expression of separate pre-pro and pre-mature polypeptides in Bacillus subtilis",,"Biochemical and Biophysical Research Communications",,"Vol. 219","No. 2","pp. 463-468",1996,
"Nagao, K.,Taguchi, Y.,Arioka, M.,Kadokura, H.,Takatsuki, A.,Yoda, K.,Yamasaki, M.,Hiroshi Kadokura","bfr1<sup>+</sup>, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily",,"Journal of Bacteriology",,"Vol. 177","No. 6","pp. 1536-1543",1995,
"Kadokura, H.,Watanabe, K.,Tsuneizumi, K.,Yoda, K.,Yamasaki, M.,Hiroshi Kadokura","Physiological and biochemical analysis of the effects of alkaline phosphatase overproduction in Escherichia coli",,"Journal of Bacteriology",,"Vol. 177","No. 12","pp. 3596-3600",1995,
"Kadokura, H.,Yoda, K.,Watanabe, S.,Kikuchi, Y.,Tamura, G.,Yamasaki, M.,Hiroshi Kadokura","Enhancement of protein secretion by optimizing protein synthesis: isolation and characterization of Escherichia coli mutants with increased secretion ability of alkaline phosphatase",,"Applied Microbiology and Biotechnology",,"Vol. 41","No. 2","pp. 163-169",1994,
"Noda, Y.,Nishikawa, S.,Shiozuka, K.-I.,Kadokura, H.,Nakajima, H.,Yoda, K.,Katayama, Y.,Morohoshi, N.,Haraguchi, T.,Yamasaki, M.,Hiroshi Kadokura","Molecular cloning of the protocatechuate 4,5-dioxygenase genes of Pseudomonas paucimobilis",,"Journal of Bacteriology",,"Vol. 172","No. 5","pp. 2704-2709",1990,
"Kadokura, H.,Yoda, K.,Imai, M.,Yamasaki, M.,Hiroshi Kadokura","Production and secretion in Escherichia coli of hepatitis b virus pre-S2 antigen as fusion proteins with ƒÀ-lactamase",,"Applied and Environmental Microbiology",,"Vol. 56","No. 9","pp. 2742-2747",1990,
"Tachibana, K.-I.,Yoda, K.,Watanabe, S.,Kadokura, H.,Katayama, Y.,Yamane, K.,Yamasaki, M.,Tamura, G.,Hiroshi Kadokura","Secretion of Bacillus subtilis ƒ¿-amylase in the periplasmic space of Escherichia coli",,"Journal of General Microbiology",,"Vol. 133","No. 7","pp. 1775-1782",1987,
"Tachibana, K.,Imai, M.,Okamoto, H.,Yoda, K.,Kadokura, H.,Katayama, Y.,Yamasaki, M.,Hiroshi Kadokura","Expression of the pre-S(2) gene of hepatitis B virus in Escherichia coli",,"Biotechnology Letters",,"Vol. 8","No. 10","pp. 677-682",1986,