"Sylvia Leo,Yusuke Kato,Yumeng Wu,Mutsumi Yokota,Masato Koike,Shiro Yui,Kiichiro Tsuchiya,Nobuaki Shiraki,Shoen Kume","The effect of Vitamin D3 and Valproic Acid on the maturation of human induced pluripotent stem cell-derived enterocyte-like cells.",,"Stem Cells",,,,,2023,May
"Zixuan Erinn Sim,Takayuki Enomoto,Nobuaki Shiraki,Shoen Kume","Protocol to generate human PSC-derived pancreatic beta-cells through methionine and zinc deprivation.",,"STAR Protocols",,,,,2023,Apr.
"Yukihiro Shimaya,Nobuaki Shiraki,Shoen Kume","Promoting pancreatic β cell proliferation: a powerful key for realizing regenerative therapy for diabetes. hionine and zinc deprivation.",,"J Diabetes Investig",,,,,2023,Apr.
"Ozawa H.,Kambe A,Hibi K,Murakami S,Oikawa A,Handa T,Fujiki K,Nakato R,Shirahige K,Kimura H,Shiraki N,Kume S.","Transient methionine deprivation triggers histone modification and potentiated differentiation of induced pluripotent stem cells.",,"Stem Cells",,"Vol. 41",,"pp. 271-286",2023,Mar.
"渡邊輝彦,Grace A. Helena,白木伸明,粂昭苑","浮遊型初代ヒト肝細胞を培養容器に接着させる培地の開発とそのアプリケーション","日本薬学会 第143年会",,,,,,2023,Mar.
"白木伸明,粂昭苑","ヒト多能性幹細胞由来膵β細胞の成熟化","第22回日本再生医療学会総会",,,,,,2023,Mar.
"Marwa ALI Ahmed,Yusuke Kato,Nobuaki Shiraki,Shoen Kume","Generation of induced pluripotent stem cell-derived beta-cells in blood amino acids-like medium.",,"Biology Open",,"Vol. 12",,,2023,Mar.
"門倉瑶乃,荒川哲大,山崎淳子,Erinn Zixuan Sim,白木伸明,粂昭苑","多能性幹細胞の未分化および分化状態における細胞内亜鉛動態解析","第22回日本再生医療学会総会",,,,,,2023,Mar.
"Marwa Ali,Yusuke Kato,Nobuaki Shiraki,Shoen Kume","Generation of induced pluripotent stem cell-derived Beta cells in blood amino acids-like medium","22nd IUNS-ICN International Congress of Nutrition",,,,,,2022,Dec.
"Dwina Juliana Warman,Takami Watanabe,Nobuaki Shiraki,Shoen Kume,Huijuan Jia,Hisanori Kato","Effects of two-day prenatal methionine deficiency on pancreatic development in newborn rats","22nd IUNS-ICN International Congress of Nutrition",,,,,,2022,Dec.
"渡邊輝彦,白木伸明,粂昭苑","ad-MEDビトリゲル2とciKIC IEC MMを用いて構築したヒトiPS細胞由来腸管上皮モデルの消化管吸収評価モデルとしての有用性","日本薬物動態学会第37回年会",,,,,,2022,Nov.
"Naoya Hiyoshi,Takayuki Enomoto,Airi Inoue,Yusuke Kato,Daisuke Sakano,Kimi Araki,Nobuaki Shiraki,Shoen Kume","Investigation of metabolite profile in plasma from Kuma mice using LC-MS/MS","MBSJ2022",,,,,,2022,Nov.
"金子 知代,榎本 孝幸,小島 慧理果,白木 伸明,粂 昭苑","メチオニン制限を組み込んだ新規iPS細胞膵臓分化方法の開発","日本アミノ酸学会第16回学術大会",,,,,,2022,Nov.
"Leo Sylvia,Kato Yusuke,Wu Yumeng,Shiraki Nobuaki,Kume Shoen","The effect of Vitamin D3 and Valproic Acid on the maturation of human induced pluripotent stem cell-derived enterocyte-like cells","MBSJ2022",,,,,,2022,Nov.
"坂野大介,粂 昭苑","新しい時代の1型糖尿病治療―再生医療の現状もふまえて",,"糖尿病プラクティス",,"Vol. 39","No. 6","pp. 625-629",2022,Sept.
"白木伸明,小澤弘樹,神戸梓沙,粂 昭苑","メチオニンは亜鉛代謝を介して多能性幹細胞を制御する","第33回日本微量元素学会学術集会",,,,,,2022,Sept.
"Fumiya Uefune,Toru Aonishi,Tetsuya Kitaguchi,Harumi Takahashi,Susumu Seino,Daisuke Sakano,Shoen Kume","Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer",,"Diabetes",,"Vol. 71","Issue 9","pp. 1946?1961",2022,Sept.
"Shiraki Nobuaki,Shoen Kume","Characterization of heterozygous ATTR Y114C amyloidosis-specific iPS cells","XVIII International Symposium on Amyloidosis ? ISA 2022",,,,,,2022,Aug.
"Shiraki Nobuaki,Shoen Kume","Characterization of heterozygous ATTR Y114C amyloidosis-specific iPS cells","XVIII International Symposium on Amyloidosis ? ISA 2022",,,,,,2022,Aug.
"粂 昭苑","Metabolic control of pluripotent stem cells in the generation of pancreatic endocrine beta cells.","第3 回JSRM-A*STARジョイントシンポジウム「Mesoderm and Endoderm」",,,,,,2022,Aug.
"Zixuan Erinn Sim,Takayuki Enomoto,Nobuaki Shiraki,Nao Furuta,Azusa Kambe,Hiroki Ozawa,Masayuki Miura,Shoen Kume","Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization.",,"Cell Reports",,"Vol. 40",,"pp. 111120",2022,July
"Kato Yusuke,Shiraki Nobuaki,Shoen Kume","Generation of functional pancreatic beta cells derived from human induced pluripotent Stem Cell-with physiological cell culture medium","ISSCR",,,,,,2022,June
"粂 昭苑","ヒトiPS細胞由来膵島の作成とインスリン分泌の制御機構解明","第95回日本内分泌学会学術総会",,,,,,2022,June
"小澤弘樹,神戸梓沙,日比滉大,木村宏,白木伸明,粂 昭苑","メチオニン除去培養によるエピジェネティック変化を伴うヒトiPS細胞分化促進","第44回日本分子生物学会",,,,,,2021,Dec.
"上船史弥,坂野大介,粂 昭苑","膵β細胞におけるD1-D2ヘテロ多量体を介したドーパミンによるインスリン分泌抑制機構の解明","第44回日本分子生物学会",,,,,,2021,Dec.
"Grace Aprilia Helena,Nobuaki Shiraki,Shoen Kume","Improvement of Primary Human Hepatocyte Cell Attachment","第44回日本分子生物学会",,,,,,2021,Dec.
"徳間啓,坂野大介,粂 昭苑","WFS1の発現低下とインスリン分泌の関連性の解明","第44回日本分子生物学会",,,,,,2021,Dec.
"井上愛里,下道隆広,坂野大介,粂 昭苑","ドパミンによる膵臓発生機構の解明","第44回日本分子生物学会",,,,,,2021,Dec.
"Yasunobu Asawa,Kei Nishida,Kazuki Kawai,Kiyotaka Domae,Hyun Seung Ban,Akihiro Kitazaki,Hiroya Asami,Jun-Ya Kohno,Satoshi Okada,Hiraku Tokuma,Daisuke Sakano,Shoen Kume,Masaru Tanaka,Hiroyuki Nakamura","Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation",,"Bioconjugate Chemistry",,,,,2021,Nov.
"粂 昭苑","アミノ酸の代謝を活用したiPS細胞の分化誘導系の構築","日本亜鉛栄養治療研究会 学術集会",,,,,,2021,Nov.
"Shoen Kume","Metabolic control of pluripotent stem cells for the generation of pancreatic beta-cells","ISSCR /JSRM International Symposium",,,,,,2021,Oct.
"粂 昭苑","多能性幹細胞の維持と膵臓β細胞分化における亜鉛シグナルの関与","日本亜鉛栄養治療研究会 学術集会",,,,,,2021,Aug.
"粂 昭苑","ヒト多能性幹細胞を用いた糖尿病の再生医療","第64回日本糖尿病学会年次学術集会",,,,,,2021,May
"粂 昭苑","ヒトiPS細胞からの膵島作成とモデル細胞としての利用","第94回日本内分泌学会",,,,,,2021,Apr.
"粂 昭苑","夢の再生医療","昭和女子大学 女性教養講座",,,,,,2021,Mar.
"Taki K, Takagi H, Hirose T, Sun R., Yaginuma H, Mizoguchi A, Kobayashi T, Sugiyama M, Tsunekawa T, Onoue T, Hagiwara D, Ito Y, Iwama S, Suga H, Banno R, Sakano D, Kume S, Arima H","Dietary sodium chloride attenuates increased β-cell mass to cause glucose intolerance in mice under a high-fat diet",,"PLOS ONE",,"Vol. 16",,"  e0248065",2021,Mar.
"粂 昭苑","ヒトiPS細胞を用いた糖尿病の再生医療研究","第20回日本再生医療学会総会",,,,,,2021,Mar.
"白木 伸明,粂 昭苑","コラーゲンビトリゲル膜と新規培地で培養したヒトiPS細胞由来小腸細胞の有用性","第20回日本再生医療学会",,,,,,2021,Mar.
"萩本隆之介,LeoSylvia Han Yun,白木 伸明,粂 昭苑","吸収腸上皮細胞への分化を促進する低分子化合物のスクリーニング","第20回日本再生医療学会",,,,,,2021,Mar.
"滝波那拓,榎本孝幸,白木 伸明,粂 昭苑","ヒ膵島移植に用いるための免疫隔離カプセルの評価","第20回日本再生医療学会",,,,,,2021,Mar.
"Yoshida S, Honjo T, Iino K, Ishibe R, Leo S, Shimada T, Watanabe T, Ishikawa M, Maeda K, Kusuhara H, Shiraki N, Kume S","Generation of human induced pluripotent stem cell-derived functional enterocyte-like cells for pharmacokinetic studies",,"Stem Cell Reports",,"Vol. 16",,"  295-308",2021,Feb.
"Shinohara M, Arakawa H, Oda Y, Shiraki N, Sugiura S, Nishiuchi T, Satoh T, Iino K, Leo S, Kato Y, Araya K, Kawanishi T, Nakatsuji T, Mitsuta M, Inamura K, Goto T, Shinha K, Nihei W, Komori K, Nishikawa M, Kume S, Kato Y, Kanamori T, Sakai Y, Kimura H","Coculture of hiPS-derived intestinal cells and enhanced human hepatocyte functions in a pneumatic pressure-driven two-organ microphysiological system",,"Scientific Reports",,"Vol. 11",,"  5437",2021,Feb.
"Sim Z.E, Shiraki N, Kume S.","Recent progress in pancreatic islet cell therapy",,"Inflammation and Regeneration",,"Vol. 41",,"  1",2021,Jan.
"芝江柾葵,上船史弥,坂野大介,粂 昭苑","マウス膵内分泌細胞のVMAT2による膵島の機能制御","分子生物学会",,,,,,2020,Dec.
"粂 昭苑","メチオニン代謝による幹細胞制御、および膵臓β細胞分化に与える影響","分子生物学会",,,,,,2020,Dec.
"吉田晋平,本荘貴之,白木 伸明,粂 昭苑","薬物動態評価モデルとしてのヒトiPS細胞由来小腸上皮細胞の開発","第5回トランスポーター研究会関東部会",,,,,,2020,Nov.
"Shoen Kume","Directed differentiation of pluripotent stem cell-derived pancreatic beta cells","日本動物細胞工学会",,,,,,2020,Nov.
"坂野大介,粂 昭苑","膵臓内分泌細胞の発生と分化における1細胞レベルにおける理解",,"糖尿病学2020",,,,"pp. 26-33",2020,Sept.
"Sakano D, Uefune F, Tokuma H, Sonoda Y, Matsuura K, Takeda N, Nakagata N, Kume K, Shiraki N, Kume S.","VMAT2 safeguards beta-cells against dopamine cytotoxicity under high-fat diet induced stress",,"Diabetes",,"Vol. 69",,"  1-15",2020,Aug.
"粂 昭苑","ヒト多能性幹細胞を用いた膵島再生研究","第93回日本内分泌学会",,,,,,2020,July
"Sakano D, Inoue A, Enomoto T, Imasaka M, Okada S, Yokota M, Koike M, Araki K, Kume S.","Insulin2 Q104del (Kuma) mutant mice develop diabetes with dominant inheritance,",,"Scientific Reports",,"Vol. 10",,"  12187",2020,July
"粂 昭苑","多能性幹細胞からの腸管細胞の作製と利用","Reprocell 主催のWeb seminar",,,,,,2020,May
"白木伸明 粂昭苑","臓器チップに要求される細胞組織ソースと細胞共用培地",,"細胞",,"Vol. 52","No. 4","pp. 174-177",2020,Apr.
"Yoshida S, Hirota M, Kawachi T, Kume S, Takahashi K","Generation of intestinal organoids derived from human pluripotent stem cells for drug testing",,"Scientific Reports",,"Vol. 10",,"  5989",2020,Apr.
"坂野大介 粂昭苑","膵β細胞再生療法の最前線",,"糖尿病・内分泌代謝科",,"Vol. 50","No. 2","pp. 1-6",2020,Feb.
"Shoen Kume","Detailed analysis at a single-cell level of cells undergoing pancreatic differentiation.",,"J Diabetes Investig",,"vol. 10",,"  20-21",2020,Jan.
"Shoen Kume","Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells",,"Biology Open",,"Vol. 8",,,2019,June
"粂昭苑","多能性幹細胞を用いた内胚葉由来の組織の作製",,"ファルマシア",,"Vol. 55","No. 6","pp. 520-527",2019,June
"Shoen Kume","A Culture Substratum with Net-like Polyamide Fibers Promotes the Differentiation of Mouse and Human Pluripotent Stem Cells to Insulin-Producing Cells.",,"Biomedical Materials",,"vol. 14","No. 4",,2019,June
"小田 雄一,篠原 満利恵,飯生 啓太,新谷 華梨,進 和美,佐藤 琢,荒川 大,白木 伸明,立野 知世,杉浦 慎治,粂 昭苑,加藤 将 夫,金森 敏幸,木村 啓志,酒井 康行","二臓器連結モデル型 Microphysiological System を用いた新鮮ヒト肝細胞とヒト iPS 細胞由来腸管上皮細胞の灌流共培養","細胞アッセイ研究会",,,,,,2019,Jan.
"柴田 伊真,下道 隆広,渡邊 輝彦,山口 宏之,白木 伸明,粂 昭苑","メチオニン除去培地とコラーゲンビトリゲル薄膜を用いて分化誘導したヒト iPS 細胞由来肝臓細胞を利用した薬物毒性試験系の構築","細胞アッセイ研究会2019",,,,,,2019,Jan.
"井上愛里,坂野大介,榎本孝幸,中原  舞,岡田  誠治,荒木喜美,粂昭苑","Insulin2タンパクへのQ104del変異導入による自然発症１型糖尿病モデルマウスの作製","第41回日本分子生物学会年会",,,,,,2018,Nov.
"日比 滉大,秋山 智彦,洪実,白木 伸明,粂 昭苑","メチオニン除去培養によるヒトiPS細胞分化促進の機序解明","第41回 日本分子生物学会年会",,,,,,2018,Nov.
"本荘 貴之,飯生 啓太,前田 和哉,渡邊 輝彦,石川 晶也,楠原 洋之,白木 伸明,粂 昭苑","ヒトiPS細胞から機能的な小腸吸収上皮細胞への新規分化誘導系の構築","第41回 日本分子生物学会年会",,,,,,2018,Nov.
"小田 雄一,篠原 満利恵,飯生 啓太,新谷 華梨,進 和美,佐藤 琢,荒川 大,白木 伸明,立野 知世,杉浦 慎治,粂 昭苑,加藤 将 夫,金森 敏幸,木村 啓志,酒井 康行","二臓器連結?圧力駆動型Microphysiological Systemを用いたヒト肝細胞とヒトiPS細胞由来腸管上皮細胞のリアルタイム灌流共培養","日本動物実験代替法学会 第31回大会",,,,,,2018,Nov.
"Zixuan Erinn Sim,Nobuaki Shiraki,Shoen Kume","Insulin supplement is essential in differentiating human induced pluripotent stem cells into pancreatic beta cells","AOCE 2018",,,,,,2018,Sept.
"Shoen Kume","iPS cell elimination in a cell sheet by methionine-free and 42 °C condition for tumor prevention.",,"Tissue Eng Part C Methods",,,,,2018,Sept.
"Shoen Kume","Future perspectives for the treatment of diabetes: importance of a regulatory framework.",,"Therapeutic Innovation & Regulatory Science",,,,,2018,Sept.
"粂昭苑","創薬応用へ向けた幹細胞由来ヒト腸細胞研究の現状",,"薬剤学",,"Vol. 78","No. 4","pp. 170-174",2018,July
"Shoen Kume","Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells.",,"Plos One",,"Vol. 13","No. 7",,2018,July
"白木 伸明,粂昭苑","ES/iPS細胞から膵β細胞への分化制御と糖尿病再生医療の現状と展開 (特集 代謝関連疾患と合併症の再生医療の最前線)",,"内分泌・糖尿病・代謝内科 = Endocrinology, diabetology & metabolism","科学評論社","Vol. 47","No. 1","pp. 7-11",2018,July
"Daisuke Sakano,Shoen Kume,Andersson O","Inhibition of Cdk5 Promotes β-cell differentiation from ductal progenitors.",,"Diabetes",,"Vol. 67",,"pp. 58-70",2018,Feb.
"Uefune F,Sonoda Y,Sakano D,Aonishi T,Kume S","Analysis of Vmat2 mediated regulation in insulin secretion","International Diabetes Federation Congress",,,,,,2017,Dec.
"坂野大介,豊田悠暉,荒木菜,粂昭苑","モノアミンシグナルによる膵β細胞の分化・増殖制御","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"豊田悠暉,荒木菜,坂野大介,粂昭苑","モノアミンによる膵β細胞の分化及び成熟化調節機構に関する研究","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"荒木菜,豊田悠暉,坂野大介,粂昭苑","膵β細胞発生におけるモノアミンシグナル伝達経路の解明","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"Shoen Kume","Sweetness induces sleep through gustatory signaling independent of nutritional value in a starved fruit fly.",,"Scientific Reports",,"Vol. 7",,,2017,July
"Hiraku Tokuma,Zixuan Erinn Sim,Fumiya Uefune,Daisuke Sakano,Nobuaki Shiraki,Shoen Kume","Establishment and analysis of hiPSC that visualize the INSULIN producing cells","第89回日本細胞生物学会大会",,,,,,2017,June
"Erinn Sim Zixuan,Saeko Momma,Nobuaki Shiraki,Shoen Kume","A NOVEL 3D SPHEROID CULTURE SYSTEM FOR GENERATING FUNCTIONAL PANCREATIC beta CELLS DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS","ISSCR 2017 Annual Meeting",,,,,,2017,June
"D.Sakano,S.Kume","Monoamine signals control beta-cell differentiation, maturation and function","糖尿病ミニシンポジウム",,,,,,2017,June
"Uefune F,Sonoda Y,Sakano D,Aonishi T,Kume S","Role of vesicular monoamine transporter 2 in insulin secretion","日本発生生物学会第50回大会",,,,,,2017,May
"門馬紗英子,白木伸明,粂昭苑","多能性幹細胞から膵臓β細胞への分化誘導過程におけるアミノ酸要求性","第71回日本栄養・食糧学会大会",,,,,,2017,May
"Hiraku Tokuma,Erinn Sim Zixuan,Fumiya Uefune,Daisuke Sakano,Nobuaki Shiraki,Shoen Kume.","Generation and Characterization of an INSULIN promoter driven mCherry Reporter Human iPS Cell Lines Using CRISPR/Cas9 system","日本発生生物学会第50回大会",,,,,,2017,May
"Shoen Kume","Erythropoietin facilitates definitive endodermal differentiation of mouse embryonic stem cells via activation of ERK signaling.",,"Am. J. of Physiology - Cell Physiology",,,,,2017,May
"Shoen Kume","Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm.",,"BMC Biotechnology",,"Vol. 17",,,2017,Feb.
"Shoen Kume","Heterogeneity of beta-cells.",,"J Diabetes Investig",,,,,2017,Jan.
"神戸梓沙,白木伸明,木村宏,粂昭苑","ヒトiPS細胞におけるメチオニン代謝とヒストン修飾の役割","第39回日本分子生物学会年会",,,,,,2016,Dec.
"古田奈央,荒川哲大,岩畑大悟,白木伸明,粂昭苑","未分化iPS細胞および分化過程おける亜鉛の役割","第39回日本分子生物学会年会",,,,,,2016,Dec.
"Daisuke Sakano,園田雄輝,Fumiya Uefune,Shoen Kume","Monoamine signals that control differentiation and proliferation of pancreatic beta cells","分子生物学会",,,,,,2016,Dec.
"坂野大介,園田雄輝,上船史弥,粂昭苑","モノアミンシグナルによる膵β細胞の増殖・分化の制御","生化学会",,,,,,2016,Sept.
"Daisuke Sakano,園田雄輝,Fumiya Uefune,Shoen Kume","Monoamine signaling controls cell proliferation and differentiation state of  pancreatic beta cell","生化学会",,,,,,2016,Sept.
"Arakawa A,Shiraki N,Tsuyama T,Shoen Kume,Iwahata D,Yamada N","Quantification of intracellular Zn, Fe, Cu within both iPS cells and differentiated cells using HPLC coupled to ICP-MS.",,"J. Anal Bioanal Tech",,"Vol. 7","Issue 1","p. 1000295",2016,July
"Omori, H.,Ogaki, S.,Daisuke Sakano,Sato, M.,Umeda, K.,Takeda, N.,Nakagata, N.,Shoen Kume","Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development",,"FEBS Letters",,,,,2016,July
"Daisuke Sakano,Choi S,Kataoka M,Shiraki N,Uesugi M,Kume K,Shoen Kume","Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass.",,"Stem cell reports",,"Vol. 7","No. 1","pp. 95-109",2016,July
"門馬紗英子,白木伸明,及川彰,粂昭苑","幹細胞の未分化維持及び分化におけるメチオニン代謝の役割","第68回日本細胞生物学会大会",,,,,,2016,June
"Nakahara Y,Muto A,Sakuma T,Yamamoto T,Shoen Kume,Kikuchi Y","Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish.",,"Genes to Cells",,"Vol. 21",,"p. 492-504",2016,June
"Tomonori Tsuyama,Nobuaki Shiraki,Shoen Kume","Definitive Endoderm Differentiation of Human Embryonic Stem Cells Combined with Selective Elimination of Undifferentiated Cells by Methionine Deprivation.",,"Methods in molecular biology (Clifton, N.J.)",,"Vol. 1341",,"pp. 173-80",2016,Apr.
"Soichiro Ogaki,Hisayoshi Omori,Mayu Morooka,Nobuaki Shiraki,Seiichi Ishida,Shoen Kume","Late stage definitive endodermal differentiation can be defined by Daf1 expression",,"BMC Developmental Biology",,"Vol. 16",,,2016,Mar.
"白木伸明,粂昭苑","アミノ酸代謝によるヒト多能性幹細胞の維持・分化誘導",,"Medical Science Digest",,"Vol. 42","No. 2","pp. 52-53",2016,Feb.
"白木伸明,粂昭苑","iPS細胞と肝胆膵疾患ー膵臓・肝臓への分化ー",,"G.I.Research",,"Vol. 24","No. 2","pp. 94-100",2016,Feb.
"白木伸明,門馬紗英子,粂昭苑","幹細胞分化におけるアミノ酸代謝の役割","第9回日本アミノ酸学会学術大会",,,,,,2016,
"坂野大介,園田雄輝,上船史弥,粂昭苑","モノアミンを介したシグナルによる膵β細胞の増殖・機能調節","分子生物学会",,,,,,2015,Dec.
"Nakashima R,Shiraki N,Daisuke Sakano,Ogaki S,Kume K,Shoen Kume","Neural cells play an inhibitory role in pancreatic differentiation of pluripotent stem cells.",,"Genes to Cells",,"Vol. 20",,"p. 1028-1045",2015,Oct.
"白木伸明,粂昭苑","iPS細胞の内胚葉系への誘導",,"日本臨牀",,"Vol. 73",,"pp. 107-114",2015,June
"白木 伸明,粂昭苑","糖尿病の再生医療 (第5土曜特集 糖尿病のすべて) -- (糖尿病対策と将来の根治・予防)",,"医学のあゆみ","医歯薬出版","Vol. 252","No. 5",,2015,May
"白木伸明,粂昭苑","幹細胞維持と分化におけるメチオニン代謝",,"日本臨牀",,"Vol. 73","No. 5","pp. 765-772",2015,May
"坂野大介,粂昭苑","-ヒト多能性幹細胞からの機能的な膵β細胞の作出-",,,"メディカルレビュー社",,,"Page 12-13",2015,Apr.
"Jun Tomita,Taro Ueno,Madoka Mitsuyoshi,Shoen Kume,Kazuhiko Kume","The NMDA Receptor Promotes Sleep in the Fruit Fly, Drosophila melanogaster",,"Plos One",,"Vol. 10","No. 5",,2015,Apr.
"Soichiro Ogaki,Mayu Morooka,Kaito Otera,Shoen Kume","A cost-effective system for differentiation of intestinal epithelium from human induced pluripotent stem cells",,"Scientific Reports",,"Vol. 5",,,2015,Apr.
"坂野 大介,粂昭苑","ケミカルバイオロジーを応用した機能的β細胞作製 (特集 糖尿病領域における再生医療の現状と展望)",,"糖尿病","医学出版","Vol. 7","No. 3",,2015,Mar.
"Daisuke Sakano,Nobuaki Shiraki,Shoen Kume","Pancreatic differentiation from murine embryonic stem cells",,"Methods in Molecular Biology",,"Vol. 1341",,"pp. 417-423",2015,Mar.
"白木伸明,粂昭苑","糖尿病の再生医学",,"医学のあゆみ",,"Vol. 252","No. 5","pp. 647-653",2015,Jan.
"白木伸明,粂昭苑","ES/iPS細胞からの膵臓β細胞への分化誘導",,"糖尿病学2015","診断と治療社",,,"  1-9",2015,
"Umeda K,Shiraki N,Shoen Kume","Hepatic Differentiation from Human Ips Cells Using M15 Cells.",,"Methods in Molecular Biology",,,,,2014,Nov.
"Yamazoe T,Shiraki N,Shoen Kume","Hepatic Differentiation from Murine and Human iPS Cells Using Nanofiber Scaffolds.",,"Methods in Molecular Biology",,,,,2014,Nov.
"白木 伸明,粂昭苑","iPS細胞研究最前線 : 疾患モデルから臓器再生まで(Vol.10)ES/iPS細胞を用いた内胚葉細胞(膵,肝,小腸)への分化誘導",,"医学のあゆみ","医歯薬出版","Vol. 251","No. 12",,2014,Nov.
"Shahjalal HM,Shiraki N,Daisuke Sakano,Kikawa K,Ogaki S,Baba H,Kume K,Shoen Kume","Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system.",,"Journal of Molecular Cellular and Biology",,"Vol. 6",,"p. 394-408",2014,Oct.
"坂野 大介,粂昭苑","VMAT2と膵β細胞分化",,"内分泌・糖尿病・代謝内科","科学評論社","Vol. 39","No. 2",,2014,Aug.
"坂野 大介,粂昭苑","膵β細胞研究の進化と展望(第1回)多能性幹細胞から膵β細胞への分化を制御するシグナル",,"Islet equality","ノバルティスファーマ","Vol. 3","No. 3",,2014,Aug.
"坂野 大介,粂昭苑","ES細胞・iPS細胞を用いた発生分化の研究と再生医学への応用 (特集 器官の発生と再生の基礎)",,"生体の科学","金原一郎記念医学医療振興財団 ; 1949-","Vol. 65","No. 3",,2014,June
"Hakim, Farzana,Kaitsuka, Taku,Raeed, Jamiruddin Mohd,Wei, Fan-Yan,Nobuaki Shiraki,Akagi, Tadayuki,Yokota, Takashi,Shoen Kume,Kazuhito Tomizawa","High Oxygen Condition Facilitates the Differentiation of Mouse and Human Pluripotent Stem Cells into Pancreatic Progenitors and Insulin-producing Cells*",,"Journal of Biological Chemistry",,"Vol. 289","No. 14","pp. 9623-9638",2014,Apr.
"Kaitsuka, Taku,Noguchi, Hirofumi,Nobuaki Shiraki,Kubo, Takuya,Wei, Fan-Yan,Hakim, Farzana,Shoen Kume,Kazuhito Tomizawa","Generation of Functional Insulin-Producing Cells From Mouse Embryonic Stem Cells Through 804G Cell-Derived Extracellular Matrix and Protein Transduction of Transcription Factors",,"Stem Cells Translational Medicine",,"Vol. 3","No. 1","pp. 114-127",2014,Apr.
"Isono, Kaori,Jono, Hirofumi,Ohya, Yuki,Nobuaki Shiraki,Taiji Yamazoe,Sugasaki, Ayaka,Era, Takumi,Fusaki, Noemi,Tasaki, Masayoshi,Ueda, Mitsuharu,Shinriki, Satoru,Inomata, Yukihiro,Shoen Kume,Ando, Yukio","Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells",,"Stem Cell Research",,"Vol. 12","No. 2","pp. 574-583",2014,Apr.
"Kazuhide Kikawa,Daisuke Sakano,Nobuaki Shiraki,Tomonori Tsuyama,Kazuhiko Kume,Fumio Endo,Shoen Kume","Beneficial Effect of Insulin Treatment on Islet Transplantation Outcomes in Akita Mice",,"Plos One",,"Vol. 9","No. 4",,2014,Apr.
"Nobuaki Shiraki,Soichiro Ogaki,Shoen Kume","Profiling of embryonic stem cell differentiation.",,"The review of diabetic studies : RDS",,"Vol. 11","No. 1","pp. 102-14",2014,Apr.
"Nobuaki Shiraki,Yasuko Shiraki,Tomonori Tsuyama,Fumiaki Obata,Masayuki Miura,Genta Nagae,Hiroyuki Aburatani,Kazuhiko Kume,Fumio Endo,Shoen Kume","Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells",,"Cell Metabolism",,"Vol. 19","No. 5","pp. 780-794",2014,Apr.
"坂野 大介,粂 昭苑","膵β細胞・膵島の再生研究 (特集 糖尿病 : 診断・治療Update)",,"最新医学","最新医学社","Vol. 69","No. 1",,2014,Feb.
"Daisuke Sakano,Shiraki N,Kikawa K,Yamazoe T,Kataoka M,Umeda K,Araki K,Mao D,Matsumoto S,Nakagata N,Andersson O,Stainier D,Endo F,Kume K,Uesugi M,Shoen Kume","VMAT2 identified as a regulator of late-stage β-cell differentiation.",,"Nature Chemical Biology",,"Vol. 10","No. 2","pp. 141-148",2014,Feb.
"池 道彦,坂東 昌子,粂昭苑,近藤科江,大垣 昌夫,大竹 文雄","シンポジウム『保育と行動経済学―学内保育園を通じて―』",,"行動経済学","Association of Behavioral Economics and Finance","Vol. 7",,"pp. 101-129",2014,
"坂野大介,白木 伸明,粂昭苑","多能性幹細胞から膵β細胞への分化 (特集 発生・分化・再生と代謝関連臓器)",,"内分泌・糖尿病・代謝内科","科学評論社","Vol. 35","No. 2",,2013,Aug.
"Ogaki S,Shiraki N,Kume K,Shoen Kume","Wnt and Notch signals guide embryonic stem cell differentiation into the intestinal lineages.",,"Stem Cells",,"Vol. 31",,"p. 1086-1096",2013,June
"Iwashita, Hidefumi,Nobuaki Shiraki,Daisuke Sakano,Ikegami, Takashi,Shiga, Masanobu,Kazuhiko Kume,Shoen Kume","Secreted Cerberus1 as a Marker for Quantification of Definitive Endoderm Differentiation of the Pluripotent Stem Cells",,"Plos One",,"Vol. 8","No. 5",,2013,Apr.
"山添 太士,白木 伸明,佐々木 裕,粂昭苑","肝臓の再生医療 (特集 再生医療)",,"日本医師会雑誌","日本医師会","Vol. 142","No. 4",,2013,Apr.
"Taiji Yamazoe,Nobuaki Shiraki,Toyoda, Masashi,Kiyokawa, Nobutaka,Okita, Hajime,Miyagawa, Yoshitaka,Akutsu, Hidenori,Umezawa, Akihiro,Sasaki, Yutaka,Kazuhiko Kume,Shoen Kume","A synthetic nanofibrillar matrix promotes in vitro hepatic differentiation of embryonic stem cells and induced pluripotent stem cells",,"Journal of Cell Science",,"Vol. 126","No. 23","pp. 5391-5399",2013,Apr.
"Kahoko Umeda,Suzuki, Keiichiro,Taiji Yamazoe,Nobuaki Shiraki,Higuchi, Yuichiro,Tokieda, Kumiko,Kazuhiko Kume,Mitani, Kohnosuke,Shoen Kume","Albumin gene targeting in human embryonic stem cells and induced pluripotent stem cells with helper-dependent adenoviral vector to monitor hepatic differentiation",,"Stem Cell Research",,"Vol. 10","No. 2","pp. 179-194",2013,Apr.
"Kawabata, Minako,Taro Ueno,Jun Tomita,Kawatani, Junko,Tomoda, Akemi,Shoen Kume,Kazuhiko Kume","Temporal organization of rest defined by actigraphy data in healthy and childhood chronic fatigue syndrome children",,"Bmc Psychiatry",,"Vol. 13",,,2013,Apr.
"Kataoka M,Kawamuro Y,Shiraki N,Miki R,Daisuke Sakano,Yoshida T,Yasukawa T,Kume K,Shoen Kume","Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment.",,,,,,,2013,Jan.
"坂野 大介,粂昭苑","多能性幹細胞からの膵β細胞分化誘導 (特集 臨床医にもわかる糖尿病基礎研究)",,"ホルモンと臨床","医学の世界社","Vol. 60","No. 11",,2012,Nov.
"白木 伸明,粂昭苑","ES/iPS細胞から膵臓への分化誘導(最前線,<特集>躍進する幹細胞研究)",,"ファルマシア","公益社団法人日本薬学会","Vol. 48","No. 9",,2012,Aug.
"Taro Ueno,Jun Tomita,Tanimoto, Hiromu,Endo, Keita,Ito, Kei,Shoen Kume,Kazuhiko Kume","Identification of a dopamine pathway that regulates sleep and arousal in Drosophila",,"Nature Neuroscience",,"Vol. 15","No. 11","pp. 1516-1523",2012,Apr.
"Takahama, Kazuhiro,Jun Tomita,Taro Ueno,Yamazaki, Masako,Shoen Kume,Kazuhiko Kume","Pan-neuronal knockdown of the c-Jun N-terminal Kinase (JNK) results in a reduction in sleep and longevity in Drosophila",,"Biochemical and Biophysical Research Communications",,"Vol. 417","No. 2","pp. 807-811",2012,Apr.
"Taro Ueno,Jun Tomita,Shoen Kume,Kazuhiko Kume","Dopamine Modulates Metabolic Rate and Temperature Sensitivity in Drosophila melanogaster",,"Plos One",,"Vol. 7","No. 2",,2012,Apr.
"Taro Ueno,Masuda, Naoki,Shoen Kume,Kazuhiko Kume","Dopamine Modulates the Rest Period Length without Perturbation of Its Power Law Distribution in Drosophila melanogaster",,"Plos One",,"Vol. 7","No. 2",,2012,Apr.
"Yamazaki, Masako,Jun Tomita,Takahama, Kazuhiro,Taro Ueno,Madoka Mitsuyoshi,Sakamoto, Erina,Shoen Kume,Kazuhiko Kume","High calorie diet augments age-associated sleep impairment in Drosophila",,"Biochemical and Biophysical Research Communications",,"Vol. 417","No. 2","pp. 812-816",2012,Apr.
"坂野大介,白木 伸明,粂昭苑","１型糖尿病治療の新しい知見  ６．ｉＰＳ細胞による糖尿病医療研究のこれから",,"糖尿病","THE JAPAN DIABETES SOCIETY","Vol. 54","No. 4",,2011,Sept.
"Nagae G,Isagawa T,Shiraki N,Fujita T,Yamamoto S,Tsutsumi S,Nonaka A,Yoshiba S,Matsusaka K,Midorikawa Y,Ishikawa S,Soejima H,Fukayama M,Suemori H,Nakatsuji N,Shoen Kume,Aburatani H","Tissue-specific demethylation in CpG-poor promoters during cellular differentiation.",,"Human Molecular Genetics",,"Vol. 20",,"p. 2710-2721",2011,July
"Taro Ueno,Shoen Kume,Kazuhiko Kume","Dopaminergic sleep regulation in Drosophila melanogaster",,"Neuroscience Research",,"Vol. 71",,"pp. E172",2011,Apr.
"Higuchi Y,Shiraki N,Shoen Kume","In vitro models of pancreatic differentiation using embryonic stem or induced pluripotent stem cells.",,"Congenital Anomalies",,"Vol. 51",,"p. 21-25",2011,Mar.
"坂野大介,白木 伸明,粂昭苑","iPS細胞による糖尿病医療研究のこれから",,"糖尿病","日本糖尿病学会","Vol. 54","No. 4",,2011,Mar.
"Matsuo, Akira,Yoshida, Tetsu,Yasukawa, Takanori,Miki, Rika,Kazuhiko Kume,Shoen Kume","Epiplakin1 is expressed in the cholangiocyte lineage cells in normal liver and adult progenitor cells in injured liver",,"Gene Expression Patterns",,"Vol. 11","No. 3-4","pp. 255-262",2011,Feb.
"Ogaki S,Harada S,Shiraki N,Kume K,Shoen Kume","An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.",,"BMC Developmental Biology",,"Vol. 11",,,2011,
"Isagawa T,Nagae G,Shiraki N,Fujita T,Sato N,Ishikawa S,Shoen Kume,Aburatani H","DNA methylation profiling of embryonic stem cell differentiation into the three germ layers.",,"PLoS ONE",,"Vol. 6",,,2011,
"Shiraki N,Yamazoe T,Qin Z,Ohgomori K,Mochitate K,Kume K,Shoen Kume","Efficient differentiation of embryonic stem cells into hepatic cells in vitro using a feeder-free basement membrane substratum.",,"Plos One",,"Vol. 6",,,2011,
"Higuchi Y,Shiraki N,Yamane K,Qin Z,Mochitate K,Araki K,Senokuchi T,Yamagata K,Hara M,Kume K,Shoen Kume","Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages.",,"Journal of Cell Sciences",,"Vol. 123",,"p. 2733-2742",2010,Aug.
"Katsumoto K,Shiraki N,Miki R,Shoen Kume","Embryonic and adult stem cell systems in mammals: ontology and regulation.",,"Development Growth Differentiation",,"Vol. 52",,"p. 115-129",2010,Jan.
"山添 太士,白木 伸明,粂昭苑","ES細胞由来分化肝細胞の創出 (AYUMI ヒト幹細胞による薬物代謝・トランスポート・副作用予測--iPS・ES細胞・間葉系細胞を用いた新たな創薬スクリーニング)",,"医学のあゆみ","医歯薬出版","Vol. 232","No. 2",,2010,
"Shiraki N,Harada S,Ogaki S,Kume K,Shoen Kume","Identification of DAF1/CD55, a novel definitive endoderm marker.",,"Cell Structure Function",,"Vol. 35",,"p. 73-80",2010,
"梅田 香穂子,白木 伸明,粂昭苑","最新医学講座 iPS細胞(9)ES細胞やiPS細胞からの膵臓分化誘導と臨床への応用",,"臨床検査","医学書院","Vol. 53","No. 10",,2009,Oct.
"樋口 裕一郎,白木 伸明,粂昭苑","iPS細胞を用いた膵臓細胞の作製と, その移植医療への応用",,"移植",,"Vol. 44","No. 3",,2009,May
"Yoshida T,Murata K,Shiraki N,Kume K,Shoen Kume","Analysis of gene expressions of embryonic stem-derived Pdx1-expressing cells: implications of genes involved in pancreas differentiation.",,"Development Growth Differentiation",,"Vol. 51",,"p. 463-472",2009,May
"Taro Ueno,Jun Tomita,Yamazaki, Masako,Shoen Kume,Kazuhiko Kume","Three state model for the evaluation of arousal and sleep in fruit fly",,"Journal of Neurogenetics",,"Vol. 23",,"pp. S81",2009,Apr.
"Shiraki N,Higuchi Y,Harada S,Umeda K,Isagawa T,Aburatani H,Kume K,Shoen Kume","Differentiation and characterization of embryonic stem cells into three germ layers.",,"Biochemical and Biophysical Research Communications",,"Vol. 381",,"p. 694-699",2009,Apr.
"Shiraki N,Umeda K,Sakashita N,Takeya M,Kume K,Shoen Kume","Differentiation of mouse and human embryonic stem cells into hepatic lineages.",,"Genes to Cells",,"Vol. 13",,"p. 731-746",2008,July
"Yoshida T,Shiraki N,Baba H,Goto M,Fujiwara S,Kume K,Shoen Kume","Expression patterns of epiplakin1 in pancreas, pancreatic cancer and regenerating pancreas.",,"Genes to Cells",,"Vol. 13",,"p. 667-678",2008,July
"Shiraki N,Yoshida T,Araki K,Umezawa A,Higuchi Y,Goto H,Kume K,Shoen Kume","Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm.",,"Stem Cells",,"Vol. 26",,"p. 874-885",2008,Apr.
"白木 伸明,粂昭苑","再生医療・遺伝子治療 ES細胞を用いた膵臓の再生医学 (新時代の糖尿病学(3)病因・診断・治療研究の進歩) -- (糖尿病治療学の進歩)",,"日本臨床","日本臨床社","Vol. 66","No. 7",,2008,
"粂昭苑,白木 伸明","膵の発生分化と幹細胞系を用いた膵の再生医学",,"臨床病理 = THE OFFICIAL JOURNAL OF JAPANESE SOCIETY OF LABORATORY MEDICINE","日本臨床検査医学会事務所","Vol. 54","No. 4",,2006,Mar.
"Shiraki, N,Lai, CJ,Hishikari, Y,Shoen Kume","TGF-beta signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells",,"Genes To Cells",,"Vol. 10","No. 6","pp. 503-516",2005,Apr.
"Ohmuraya, M,Hirota, M,Araki, M,Mizushima, N,Matsui, M,Mizumoto, T,Haruna, K,Shoen Kume,Takeya, M,Ogawa, M,Araki, K,Yamamura, K","Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice",,"Gastroenterology",,"Vol. 129","No. 2","pp. 696-705",2005,Apr.
"Shoen Kume","The molecular basis and prospects in pancreatic development",,"Development Growth & Differentiation",,"Vol. 47","No. 6","pp. 367-374",2005,Apr.
"Kume, K,Shoen Kume,Park, SK,Hirsh, J,Jackson, FR","Dopamine is a regulator of arousal in the fruit fly",,"Journal of Neuroscience",,"Vol. 25","No. 32","pp. 7377-7384",2005,Apr.
"Kodama, S,Toyonaga, T,Kondo, T,Matsumoto, K,Tsuruzoe, K,Kawashima, J,Goto, H,Kume, K,Shoen Kume,Sakakida, M,Araki, E","Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice",,"Biochemical and Biophysical Research Communications",,"Vol. 327","No. 4","pp. 1170-1178",2005,Apr.
"Kume, S,Shoen Kume","Stem-cell-based approaches for regenerative medicine",,"Development Growth & Differentiation",,"Vol. 47","No. 6","pp. 393-402",2005,Apr.
"Shoen Kume","Stem cell-based approaches for regenerative medicine.",,"Development Growth & Differentiation",,"Vol. 47","No. 6","pp. 393-402",2005,Apr.
"Saneyoshi, T,Shoen Kume,Mikoshiba, K","Calcium/calmodulin-dependent protein kinase I in Xenopus laevis",,"Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology",,"Vol. 134","No. 3","pp. 499-507",2003,Apr.
"Rajagopal, J,Anderson, WJ,Shoen Kume,Martinez, OI,Melton, DA","Insulin staining of ES cell progeny from insulin uptake",,"Science",,"Vol. 299","No. 5605","pp. 363",2003,
"Saneyoshi, T,Kume, S,Amasaki, Y,Mikoshiba, K,Shoen Kume","The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos",,"Nature",,"Vol. 417","No. 6886","pp. 295-299",2002,Apr.
"Kume, S,Saneyoshi, T,Mikoshiba, K,Shoen Kume","Desensitization of IP3-induced Ca2+ release by overexpression of a constitutively active Gq alpha protein converts ventral to dorsal fate in Xenopus early embryos",,"Development Growth & Differentiation",,"Vol. 42","No. 4","pp. 327-335",2000,Apr.
"Shoen Kume,Inoue, T,Mikoshiba, K","G alpha s family G proteins activate IP3-Ca2+ signaling via G beta gamma and transduce ventralizing signals in Xenopus",,"Developmental Biology",,"Vol. 226","No. 1","pp. 88-103",2000,Apr.
"Shoen Kume","Role of the inositol 1,4,5-trisphosphate receptor in early embryonic development",,"Cellular and Molecular Life Sciences",,"Vol. 56","No. 3-4","pp. 296-304",1999,
"Shoen Kume,Mikoshiba, K","[Role of PI signaling in early development].",,"Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme",,"Vol. 43","No. 12 Suppl","pp. 1834-40",1998,Apr.
"Mikoshiba, Katsuhiko,Shoen Kume,Muto, Akira","Role of IP3 receptor/Ca2+ channel on egg and embryo development",,"Zygote",,"Vol. 6","No. SUPPL. 1","pp. S56",1998,Apr.
"Kume, S,Muto, A,Okano, H,Mikoshiba, K,Shoen Kume","Developmental expression of the inositol 1,4,5-trisphosphate receptor and localization of inositol 1,4,5-trisphosphate during early embryogenesis in Xenopus laevis",,"Mechanisms of Development",,"Vol. 66","No. 1-2","pp. 157-168",1997,Apr.
"Kume, S,Muto, A,Inoue, T,Suga, K,Okano, H,Mikoshiba, K,Shoen Kume","Role of inositol 1,4,5-trisphosphate receptor in ventral signaling in Xenopus embryos",,"Science",,"Vol. 278","No. 5345","pp. 1940-1943",1997,Apr.
"Umemori, H,Inoue, T,Kume, S,Sekiyama, N,Nagao, M,Itoh, H,Nakanishi, S,Mikoshiba, K,Yamamoto, T,Shoen Kume","Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit",,"Science",,"Vol. 276","No. 5320","pp. 1878-1881",1997,Apr.
"Kume, S,Yamamoto, A,Inoue, T,Muto, A,Okano, H,Mikoshiba, K,Shoen Kume","Developmental expression of the inositol 1,4,5-trisphosphate receptor and structural changes in the endoplasmic reticulum during oogenesis and meiotic maturation of Xenopus laevis",,"Developmental Biology",,"Vol. 182","No. 2","pp. 228-239",1997,Apr.
"Muto, A,Kume, S,Inoue, T,Okano, H,Mikoshiba, K,Shoen Kume","Calcium waves along the cleavage furrows in cleavage-stage Xenopus embryos and its inhibition by heparin",,"Journal of Cell Biology",,"Vol. 135","No. 1","pp. 181-190",1996,Apr.
"HONDA, Z,TAKANO, T,HIROSE, N,SUZUKI, T,MUTO, A,KUME, S,MIKOSHIBA, K,ITOH, K,SHIMIZU, T,Shoen Kume","G(Q) PATHWAY DESENSITIZES CHEMOTACTIC RECEPTOR-INDUCED CALCIUM SIGNALING VIA INOSITOL TRISPHOSPHATE RECEPTOR DOWN-REGULATION",,"Journal of Biological Chemistry",,"Vol. 270","No. 9","pp. 4840-4844",1995,Apr.
"KUME, S,MUTO, A,ARUGA, J,NAKAGAWA, T,MICHIKAWA, T,FURUICHI, T,NAKADE, S,OKANO, H,MIKOSHIBA, K,Shoen Kume","THE XENOPUS IP(3) RECEPTOR - STRUCTURE, FUNCTION, AND LOCALIZATION IN OOCYTES AND EGGS",,"Cell",,"Vol. 73","No. 3","pp. 555-570",1993,Apr.
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