@book{CTT100811738,
  author = {Yoshiaki Masaki and Akihiro Ohkubo and Kohji Seio and Mitsuo Sekine},
  title = {Effects of 2'-O-Modifications on RNA Duplex Stability},
  publisher = {Springer},
  year = 2018,
}

@book{CTT100786536,
  author = {清尾康志 and 大窪章寛},
  title = {塩基部無保護ホスホロアミダイト法による核酸合成},
  publisher = {シーエムシー出版},
  year = 2018,
}

@book{CTT100722761,
  author = {KOHJI SEIO and Takashi Kanamori and Akihiro Ohkubo and MITSUO SEKINE},
  title = {Synthesis and Fluorescence Properties of Nucleosides with Pyrimimidine-Type Base Moieties},
  publisher = {},
  year = 2016,
}

@book{CTT100716366,
  author = {大窪章寛},
  title = {オリゴヌクレオチドの固相合成},
  publisher = {},
  year = 2015,
}

@book{CTT100785543,
  author = {Ohkubo Akihiro and Okamoto Itaru and Kasuya Rintaro and Sakamoto Kazushi and Sasami Takeshi and Odawara Yoko and Masaki Yoshiaki and Sakaue Toshiyuki and Nagasawa Hiroshi and Tsukahara Toshifumi and Seio Kohji and Sekine Mitsuo},
  title = {Protected DNA probes (PDP): A new strategy for gene detection},
  publisher = {},
  year = 2008,
}

@article{CTT100836620,
  author = {Akihiro Ohkubo and Shuuhei Nishizawa},
  title = {Chemical synthesis and biochemical characterization of cyclic oligonucleotides containing acyl groups at both 5´- and 3´-terminal positions},
  journal = {Bioorg. Med. Chem.},
  year = 2020,
}

@article{CTT100836619,
  author = {Akihiro Ohkubo and Kousuke Mutou and Lintaro Watanabe and Shuuhei Nishizawa and Shugo Hisamatsu and Takashi Kanamori},
  title = {Chemical synthesis and properties of modified oligonucleotides containing 5'-amino-5'-deoxy-5'-hydroxymethylthymidine residues},
  journal = {Bioorg. Med. Chem.},
  year = 2020,
}

@article{CTT100836618,
  author = {Akihiro Ohkubo and Tatsuya Ohnishi and Shuuhei Nishizawa and Yuri Nishimura and Shugo Hisamatsu},
  title = {The ability of a triplex-forming oligonucleotide to recognize T-A and C-G base pairs in a DNA duplex is enhanced by incorporating N-acetyl-2,7-diaminoquinoline},
  journal = {Bioorg. Med. Chem.},
  year = 2020,
}

@article{CTT100812079,
  author = {Takashi Kanamori and Masaki Y and Oda Y and Ohzeki H and Ohkubo A and Sekine M and Seio K.},
  title = {DNA triplex-based fluorescence turn-on sensors for adenosine using a fluorescent molecular rotor 5-(3-methylbenzofuran-2-yl) deoxyuridine},
  journal = {Org. Biomol Chem.},
  year = 2019,
}

@article{CTT100781220,
  author = {Takeshi Inde and Shuhei Nishizawa and Yuusaku Hattori and Takashi Kanamori and Hideya Yuasa and Kohji Seio and Mitsuo Sekine and Akihiro Ohkubo},
  title = {Synthesis of and triplex formation in oligonucleotides containing 2’-deoxy-6-thioxanthosine},
  journal = {},
  year = 2018,
}

@article{CTT100759919,
  author = {Tanasak Kaewsomboon and Shuhei Nishizawa and Takashi Kanamori and Hideya Yuasa and Akihiro Ohkubo},
  title = {pH-Dependent Switching of Base Pairs Using Artificial Nucleobases with Carboxyl Groups},
  journal = {J. Org. Chem.},
  year = 2018,
}

@article{CTT100748625,
  author = {Takashi Kanamori and Takashi Sawamura and Tatsumi Tanaka and Izumi Sotokawa and Ryota Mori and Kotaro Inada and Akihiro Ohkubo and Shun-Ichiro Ogura and Yasutoshi Murayama and Eigo Otsuji and Hideya Yuasa},
  title = {Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for HeLa and RAW264.7 cells, enhancing their photodamaging effect.},
  journal = {Bioorg. Med. Chem.},
  year = 2017,
}

@article{CTT100748623,
  author = {Takashi Kanamori and Akihiro Takamura and Nobuhiro Tago and Yoshiaki Masaki and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio},
  title = {Fluorescence enhancement of oligodeoxynucleotides modified with green fluorescent protein chromophore mimics upon triplex formation.},
  journal = {Org. Biomol. Chem.},
  year = 2017,
}

@article{CTT100722448,
  author = {Yoshiaki Masaki and Hugo Itou and Yuki Oda and Kazufumi Yamazaki and Nobuhiro Tago and Kentaro Ohno and Nozomi Ishii and Hirosuke Tsunoda and Takashi Kanamori and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio},
  title = {Enzymatic synthesis and reverse transcription of RNAs incorporating 2'-O-carbamoyl uridine triphosphate},
  journal = {Chemical Communications},
  year = 2016,
}

@article{CTT100716346,
  author = {Yu Ito and Yoshiaki Masaki and Takashi Kanamori and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE},
  title = {Synthesis of 5-[3-(2-aminopyrimidin-4-yl)aminopropyn-1-yl]uracil derivative that recognizes Ade-Thy base pairs in double-stranded DNA},
  journal = {Bioorg. Med. Chem. Lett.},
  year = 2016,
}

@article{CTT100716352,
  author = {Nobuhiro Tago and Yoshiaki Masaki and Takashi Kanamori and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE},
  title = {A New Microfluidic Phase-Transfer Reaction Using HPLC Guard Columns as the Reactor for the N3 Protection of Uridine Derivatives},
  journal = {SYNLETT},
  year = 2015,
}

@article{CTT100714589,
  author = {Takashi Sawamura and Tatsumi Tanaka and hiroyuki ishige and masayuki Iizuka and yasutoshi murayama and Eigo Otsuji and Akihiro Ohkubo and Shun-ichiro OGURA and HIDEYA YUASA},
  title = {The Effect of Coatings on the Affinity of Lanthanide Nanoparticles to MKN45 and HeLa Cancer Cells and Improvement in Photodynamic Therapy Efficiency},
  journal = {International Journal of Molecular Sciences},
  year = 2015,
}

@article{CTT100714786,
  author = {Ohkubo and Kenji Yamada and Yu Ito and Kiichi Yoshimura and Koichiro Miyauchi and Takashi Kanamori and Yoshiaki Masaki and KOHJI SEIO and HIDEYA YUASA and Mitsuo},
  title = {Synthesis and Triplex-forming Properties of Oligonucleotides Capable of Recognizing Corresponding DNA Duplexes Containing Four Base Pairs},
  journal = {Nucleic Acids Res.},
  year = 2015,
}

@article{CTT100716358,
  author = {Takahito Tomori and Yuya Miyatake and Takashi Kanamori and Yoshiaki Masaki and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE},
  title = {Synthesis of peptide nucleic acids containing pyridazine derivatives as cytosine and thymine analogs, and their duplexes with complementary oligodeoxynucleotides},
  journal = {ORG. LETT.},
  year = 2015,
}

@article{CTT100716360,
  author = {munefumi tokugawa and Kazuhei Kaneko and Masanori Saito and Takashi Kanamori and Yoshiaki Masaki and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE},
  title = {Synthesis of responsive fluorescent Nucleobases 7-(Benzofuran-2-yl)-7- deazahypoxanthine and 7-(benzofuran-2-yl)-7-deazaguanine using cross-coupling reaction},
  journal = {CHEM. LETT.},
  year = 2015,
}

@article{CTT100716361,
  author = {Takashi Kanamori and Hiroki Ohzeki and Yoshiaki Masaki and Akihiro Ohkubo and MITSUO SEKINE and KOHJI SEIO},
  title = {Controlling the fluorescence of benzofuran-modified uracil residues in oligonucleotides by triple-helix formation},
  journal = {Chembiochem},
  year = 2015,
}

@article{CTT100714791,
  author = {Junji Takeuchi and Akihiro Ohkubo and Hideya Yuasa},
  title = {A Ring-Flippable Sugar as a Stimuli-Responsive Component of Liposomes},
  journal = {Chemistry—An Asian Journal},
  year = 2015,
}

@article{CTT100785547,
  author = {Masaki Yoshiaki and Yamada Takeshi and Saneyoshi Hisao and Ohkubo Akihiro and Seio Kohji and Sekine Mitsuo},
  title = {Synthesis and Exon-Skipping Activity of Chemically Modified RNAs},
  journal = {Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications},
  year = 2014,
}

@article{CTT100785023,
  author = {K. Yamada and Y. Masaki and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine},
  title = {A new modified cytosine base capable of base pairing with guanine using four hydrogen bonds},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2014,
}

@article{CTT100785027,
  author = {Y. Masaki and R. Miyasaka and K. Hirai and T. Kanamori and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine},
  title = {Properties of 5- and/or 2-modified 2 '-O-cyanoethyl uridine residue: 2 '-O-cyanoethyl-5-propynyl-2-thiouridine as an efficient duplex stabilizing component},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2014,
}

@article{CTT100785013,
  author = {T. Yamada and Y. Masaki and N. Okaniwa and T. Kanamori and A. Ohkubo and H. Tsunoda and K. Seio and M. Sekine},
  title = {Synthesis and properties of oligonucleotides modified with 2 '-O-(2-carboxyethyl)nucleotides and their carbamoyl derivatives},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2014,
}

@article{CTT100785032,
  author = {K. Seio and M. Tokugawa and H. Tsunoda and A. Ohkubo and F. Arisaka and M. Sekine},
  title = {Assembly of pyrene-modified DNA/RNA duplexes incorporating a G-rich single strand region},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS},
  year = 2013,
}

@article{CTT100785035,
  author = {Y. Iijima and S. Kojima and E. Kodama and S. Kurohagi and T. Kanamori and Y. Masaki and A. Ohkubo and M. Sekine and K. Seio},
  title = {Modified oligodeoxynucleotide primers for reverse-transcription of target RNAs that can discriminate among length variants at the 3 '-terminus},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2013,
}

@article{CTT100785034,
  author = {A. Ohkubo and Y. Kondo and M. Suzuki and H. Kobayashi and T. Kanamori and Y. Masaki and K. Seio and K. Nagai and M. Sekine},
  title = {Chemical synthesis of U1 snRNA derivatives},
  journal = {ORGANIC LETTERS},
  year = 2013,
}

@article{CTT100785033,
  author = {K. Seio and T. Kanamori and M. Tokugawa and H. Ohzeki and Y. Masaki and H. Tsunoda and A. Ohkubo and M. Sekine},
  title = {Fluorescent properties of oligonucleotides doubly modified with an indole-fused cytosine analog and 2-aminopurine},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2013,
}

@article{CTT100785029,
  author = {K. Yamada and A. Ohkubo and Y. Esaka and T. Kanamori and Y. Masaki and K. Seio and M. Sekine},
  title = {Base recognition of gap sites in DNA-DNA and DNA-RNA duplexes by short oligonucleotides},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS},
  year = 2013,
}

@article{CTT100785031,
  author = {K. Yamada and Y. Hattori and T. Inde and T. Kanamori and A. Ohkubo and K. Seio and M. Sekine},
  title = {Remarkable stabilization of antiparallel DNA triplexes by strong stacking effects of consecutively modified nucleobases containing thiocarbonyl groups},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS},
  year = 2013,
}

@article{CTT100785037,
  author = {K. Seio and M. Tokugawa and T. Kanamori and H. Tsunoda and A. Ohkubo and M. Sekine},
  title = {Synthesis and properties of cationic 2 '-O- N-(4-aminobutyl)carbamoyl modified oligonucleotides},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS},
  year = 2012,
}

@article{CTT100785043,
  author = {T. Harakawa and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine},
  title = {Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts},
  journal = {Bioorganic & Medicinal Chemistry Letters},
  year = 2012,
}

@article{CTT100785039,
  author = {A. Ohkubo and N. Tago and A. Yokouchi and ; Y. Nishino and K. Yamada and H. Tsunoda and K. Seio and M. Sekine},
  title = {Synthesis of 5 '-terminal capped oligonucleotides using O-N phosphoryl migration of phosphoramidite derivatives},
  journal = {ORGANIC LETTERS},
  year = 2012,
}

@article{CTT100785042,
  author = {T. Kanamori and Y. Masaki and M. Mizuta and H. Tsunoda and A. Ohkubo and M. Sekine and K. Seio},
  title = {DNA duplexes and triplex-forming oligodeoxynucleotides incorporating modified nucleosides forming stable and selective triplexes},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2012,
}

@article{CTT100785041,
  author = {Y. Masaki and R. Miyasaka and K. Hirai and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine},
  title = {Prediction of the stability of modified RNA duplexes based on deformability analysis: Oligoribonucleotide derivatives modified with 2 '-o-cyanoethyl-5-propynyl-2-thiouridine as a promising component},
  journal = {CHEMICAL COMMUNICATIONS},
  year = 2012,
}

@article{CTT100785040,
  author = {A. Ohkubo and Y. Nishino and Y. Ito and H. Tsunoda and K. Seio and M. Sekine},
  title = {Formation of new base pairs between inosine and 5-methyl-2-thiocytidine derivatives},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2012,
}

@article{CTT100785038,
  author = {K. Seio and S. Kurohagi and E. Kodama and Y. Masaki and H. Tsunoda and A. Ohkubo and M. Sekine},
  title = {Short-RNA selective binding of oligonucleotides modified using adenosine and guanosine derivatives that possess cyclohexyl phosphates as substituents},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2012,
}

@article{CTT100785047,
  author = {A. Ohkubo and A. Yokouchi and K. Yamada and H. Tsunoda and K. Seio and M. Sekine},
  title = {Synthesis and properties of oligonucleotides having 5 '-terminal 2,2,7-trimethylguanosine cap analogues},
  journal = {NUCLEIC ACID THERAPEUTICS},
  year = 2011,
}

@article{CTT100785044,
  author = {T. Yamada and N. Okaniwa and H. Saneyoshi and A. Ohkubo and K. Seio and T. Nagata and Y. Aoki and S. Takeda and M. Sekine},
  title = {Synthesis of 2 '-O- 2-(N-methylcarbamoyl)ethyl ribonucleosides using oxa-michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides},
  journal = {JOURNAL OF ORGANIC CHEMISTRY},
  year = 2011,
}

@article{CTT100785045,
  author = {H. Tsunoda and T. Kudo and Y. Masaki and A. Ohkubo and K. Seio and M. Sekine},
  title = {Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions},
  journal = {NUCLEIC ACIDS RESEARCH},
  year = 2011,
}

@article{CTT100785049,
  author = {S. Q. Cao and I. Okamoto and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis and triplex-forming properties of oligonucleotides containing thio-substituted C-nucleoside 4-thiopseudoisocytidine},
  journal = {TETRAHEDRON LETTERS},
  year = 2011,
}

@article{CTT100785046,
  author = {M. Sekine and Y. Oeda and Y. Iijima and H. Taguchi and A. Ohkubo and K. Seio},
  title = {Synthesis and hybridization properties of 2 '-O-methylated oligoribonucleotides incorporating 2 '-O-naphthyluridines},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2011,
}

@article{CTT100785048,
  author = {A. Ohkubo and Y. Nishino and A. Yokouchi and Y. Ito and Y. Noma and Y. Kakishima and Y. Masaki and H. Tsunoda and K. Seio and M. Sekine},
  title = {Stable triplex formation using the strong stacking effect of consecutive thionucleoside moieties},
  journal = {CHEMICAL COMMUNICATIONS},
  year = 2011,
}

@article{CTT100785053,
  author = {H. Tsunoda and T. Kudo and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis of oligodeoxynucleotides using fully protected deoxynucleoside 3 '-phosphoramidite building blocks and base recognition of oligodeoxynucleotides incorporating N-3-cyano-ethylthymine},
  journal = {MOLECULES},
  year = 2010,
}

@article{CTT100785050,
  author = {K. Yamada and H. Taguchi and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis and biochemical properties of oligodeoxynucleotides acylated by the chemically stable 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5 ' or 3 ' terminus},
  journal = {Tetrahedron letters},
  year = 2010,
}

@article{CTT100785058,
  author = {A. Ohkubo and T. Sakaue and H. Tsunoda and K. Seio and M. Sekine},
  title = {Synthesis and hybridization properties of oligonucleotides incorporating bi- and tricyclic cytosine derivatives},
  journal = {Chemistry letters},
  year = 2010,
}

@article{CTT100785060,
  author = {A. Ohkubo and Y. Kuwayama and Y. Nishino and H. Tsunoda and K. Seio and M. Sekine},
  title = {Oligonucleotide synthesis involving deprotection of amidine-type protecting groups for nucleobases under acidic conditions},
  journal = {ORGANIC LETTERS},
  year = 2010,
}

@article{CTT100785062,
  author = {Y. Masaki and R. Miyasaka and A. Ohkubo and K. Seio and M. Sekine},
  title = {Linear relationship between deformability and thermal stability of 2 '-O-modified RNA hetero duplexes},
  journal = {JOURNAL OF PHYSICAL CHEMISTRY B},
  year = 2010,
}

@article{CTT100785061,
  author = {Y. Masaki and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis of 6-N-(benzothiazol-2-yl)deoxyadenosine and its exciton-coupled circular dichroism},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2010,
}

@article{CTT100815690,
  author = {Magat Juan, E.C. and Shimizu, S. and Ma, X. and Kurose, T. and Haraguchi, T. and Zhang, F. and Tsunoda, M. and Akihiro Ohkubo and Sekine, M. and Shibata, T. and Millington, C.L. and Williams, D.M. and Takénaka, A.},
  title = {Insights into the DNA stabilizing contributions of a bicyclic cytosine analogue: Crystal structures of DNA duplexes containing 7,8-dihydropyrido [2,3-d]pyrimidin-2-one},
  journal = {Nucleic Acids Research},
  year = 2010,
}

@article{CTT100785055,
  author = {K. Seio and M. Shiraishi and E. Utagawa and A. Ohkubo and M. Sekine},
  title = {Synthesis of oligodeoxynucleotides using the oxidatively cleavable 4-methoxytritylthio (MMTrS) group for protection of the 5 '-hydroxyl group},
  journal = {NEW JOURNAL OF CHEMISTRY},
  year = 2010,
}

@article{CTT100785515,
  author = {Y. Oeda and Y. Iijima and H. Taguchi and A. Ohkubo and K. Seio and M. Sekine},
  title = {Microwave-Assisted Synthesis of 2 '-O-Aryluridine Derivatives},
  journal = {ORGANIC LETTERS},
  year = 2009,
}

@article{CTT100785506,
  author = {K. Seio and R. Tawarada and T. Sasami and M. Serizawa and M. Ise and A. Ohkubo and M. Sekine},
  title = {Synthesis and hybridization of 2 '-O-methyl-RNAs incorporating 2 '-O-carbamoyluridine and unique participation of the carbamoyl group in U-G base pair},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2009,
}

@article{CTT100785549,
  author = {Seio Kohji and Miyazaki Kazuya and Kurohagi Sayako and Masaki Yoshiaki and Tsunoda Hirosuke and Ohkubo Akihiro and Sekine Mitsuo},
  title = {Synthesis and properties of terminally modified oligonucleotides capable of short-RNA selective hybridization.},
  journal = {Nucleic acids symposium series (2004)},
  year = 2009,
}

@article{CTT100785504,
  author = {K. Yamada and H. Taguchi and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis and properties of nucleoside derivatives acylated by chemically stable 2-(trimethylsilyl)benzoyl group},
  journal = {Bioorganic & Medicinal Chemistry},
  year = 2009,
}

@article{CTT100785512,
  author = {A. Ohkubo and K. Sasaki and Y. Noma and H. Tsunoda and K. Seio and M. Sekine},
  title = {Efficient solid-phase synthesis of oligodeoxynucleotides having a 5 '-terminal 2,2,7-trimethylguanosine pyrophosphate linkage},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2009,
}

@article{CTT100785516,
  author = {M. Mizuta and K. Seio and A. Ohkubo and M. Sekine},
  title = {Fluorescence Properties of Pyrimidopyrimidoindole Nucleoside dC(PPI) Incorporated into Oligodeoxynucleotides},
  journal = {JOURNAL OF PHYSICAL CHEMISTRY B},
  year = 2009,
}

@article{CTT100785509,
  author = {T. Sasami and R. Tawarada and A. Ohkubo and M. Sekine and K. Seio},
  title = {Computational evaluation of the stability of 2 '-O-methyl-RNA/RNA duplexes incorporating 3-deazaguanine derivatives by ab initio calculations and a molecular dynamics simulation},
  journal = {JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM},
  year = 2009,
}

@article{CTT100785513,
  author = {A. Ohkubo and Y. Noma and K. Aoki and H. Tsunoda and K. Seio and M. Sekine},
  title = {Introduction of 3 '-Terminal Nucleosides Having a Silyl-Type Linker into Polymer Supports without Base Protection},
  journal = {JOURNAL OF ORGANIC CHEMISTRY},
  year = 2009,
}

@article{CTT100785510,
  author = {T. Sasami and Y. Odawara and A. Ohkubo and M. Sekine and K. Seio},
  title = {Synthesis of oligodeoxynucleotides incorporating 2-N-carbamoylguanine and evaluation of the hybridization properties},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2009,
}

@article{CTT100785517,
  author = {K. Miyata and R. Tamamushi and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis and Triplex Formation of Oligonucleotides Containing 8-Thioxodeoxyadenosine},
  journal = {Organic Letters},
  year = 2009,
}

@article{CTT100785514,
  author = {A. Ohkubo and R. Kasuya and K. Miyata and H. Tsunoda and K. Seio and M. Sekine},
  title = {New thermolytic carbamoyl groups for the protection of nucleobases},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2009,
}

@article{CTT100785507,
  author = {K. Seio and Y. Takaku and K. Miyazaki and S. Kurohagi and Y. Masaki and A. Ohkubo and M. Sekine},
  title = {Synthesis of terminally modified oligonucleotides and their hybridization dependence on the size of the target RNAs},
  journal = {ORGANIC & BIOMOLECULAR CHEMISTRY},
  year = 2009,
}

@article{CTT100785524,
  author = {K. Seio and M. Mizuta and K. Tasaki and K. Tamaki and A. Ohkubo and M. Sekine},
  title = {Hybridization-dependent fluorescence of oligodeoxynucleotides incorporating new pyrene-modified adenosine residues},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2008,
}

@article{CTT100785527,
  author = {A. Ohkubo and Y. Kuwayama and T. Kudo and H. Tsunoda and K. Seio and M. Sekine},
  title = {O-selective condensation using P-N bond cleavage in RNA synthesis without base protection},
  journal = {Organic letters},
  year = 2008,
}

@article{CTT100785553,
  author = {M. Mizuta and J. I. Banba and T. Kanamori and R. Tawarada and A. Ohkubo and M. Sekine and K. Seio},
  title = {New nucleotide pairs for stable DNA triplexes stabilized by stacking interaction},
  journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY},
  year = 2008,
}

@article{CTT100785552,
  author = {A. Ohkubo and R. Kasuya and K. Aoki and A. Kobori and H. Taguchi and K. Seio and M. Sekine},
  title = {Efficient synthesis of functionalized oligodeoxyribonucleotides with base-labile groups using a new silyl linker},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY},
  year = 2008,
}

@article{CTT100785525,
  author = {H. Saneyoshi and K. Tamaki and A. Ohkubo and K. Seio and M. Sekine},
  title = {Synthesis and hybridization properties of 2 '-O-(tetrazol-5-yl)ethyl-modified oligonucleotides},
  journal = {TETRAHEDRON},
  year = 2008,
}

@article{CTT100785528,
  author = {A. Ohkubo and R. Kasuya and K. Sakamoto and K. Miyata and H. Taguchi and H. Nagasawa and T. Tsukahara and T. Watanobe and Y. Maki and K. Seio and M. Sekine},
  title = {'Protected DNA Probes' capable of strong hybridization without removal of base protecting groups},
  journal = {NUCLEIC ACIDS RESEARCH},
  year = 2008,
}

@article{CTT100785518,
  author = {H. Tsunoda and A. Ohkubo and H. Taguchi and K. Seio and M. Sekine},
  title = {Synthesis and properties of DNA oligomers containing 2 '-deoxynucleoside N-oxide derivatives},
  journal = {JOURNAL OF ORGANIC CHEMISTRY},
  year = 2008,
}

@article{CTT100785523,
  author = {M. Sumino and A. Ohkubo and H. Taguchi and K. Seio and M. Sekine},
  title = {Synthesis and properties of oligodeoxynucleotides containing 5-carboxy-2'-deoxycytidines},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS},
  year = 2008,
}

@article{CTT100785559,
  author = {A. Ohkubo and K. Tanaka and H. Taguchi and K. Seio and H. Nagasawa and T. Tsukahara and M. Sekine},
  title = {An effective method for the in situ synthesis of DNA-CPG conjugates using chemical ligation technology as tools for SNP analysis},
  journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS},
  year = 2007,
}

@article{CTT100785544,
  author = {Saneyoshi Hisao and Okamoto Itaru and Masaki Yoshiaki and Ohkubo Akihiro and Seio Kohji and Mitsuo},
  title = {Facile synthesis of 2 '-O-cyanoethyluridine by ring-opening reaction of 2,2 '-anhydrouridine with cyanoethyl trimethylsilyl ether in the presence of BF3 center dot Et2O},
  journal = {Tetrahedron Letters},
  year = 2007,
}

@article{CTT100785554,
  author = {E. Utagawa and A. Ohkubo and M. Sekine and K. Seio},
  title = {Synthesis of branched Oligonucleotides with three different sequences using an oxidatively removable tritylthio group},
  journal = {JOURNAL OF ORGANIC CHEMISTRY},
  year = 2007,
}

@article{CTT100785560,
  author = {A. Ohkubo and H. Taguchi and K. Seio and H. Nagasawa and T. Tsukahara and M. Sekine},
  title = {A new hydrophobic linker effective for the in situ synthesis of DNA-CPG conjugates as tools for SNP analysis},
  journal = {TETRAHEDRON LETTERS},
  year = 2007,
}

@article{CTT100785557,
  author = {T. Sasami and Y. Odawara and A. Ohkubo and M. Sekine and K. Seio},
  title = {Synthesis and hybridization properties of oligodeoxynucleotides incorporating 2-N-carbamoylguanine derivatives as guanine analogs},
  journal = {TETRAHEDRON LETTERS},
  year = 2007,
}

@article{CTT100785556,
  author = {K. Seio and T. Sasami and A. Ohkubo and K. Ando and M. Sekine},
  title = {Highly selective recognition of cytosine over uracil and adenine by a guanine analogue, 2-N-Acetyl-3-deazaguanine, in 2 '-O-Methyl-RNA/RNA and DNA duplexes},
  journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY},
  year = 2007,
}

@article{CTT100785565,
  author = {K. Miyata and R. Mineo and R. Tamamushi and M. Mizuta and A. Ohkubo and H. Taguchi and K. Seio and T. Santa and M. Sekine},
  title = {Synthesis and fluorescent properties of bi- and tricyclic 4-N-carbamoyldeoxycytidine derivatives},
  journal = {JOURNAL OF ORGANIC CHEMISTRY},
  year = 2007,
}

@article{CTT100785563,
  author = {M. Mizuta and K. Seio and K. Miyata and A. Ohkubo and H. Taguchi and M. Sekine},
  title = {A pyrimidopyrimidoindole nucleoside (dC(PPI)): Photophysical properties and thermal stability of the modified DNA duplexes},
  journal = {NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS},
  year = 2007,
}

@article{CTT100785555,
  author = {K. Seio and T. Terada and M. Mizuta and A. Ohkubo and H. Taguchi and M. Sekine},
  title = {Synthesis and hybridization properties of oligodeoxynucleotides with long-chain linkers},
  journal = {HELVETICA CHIMICA ACTA},
  year = 2007,
}

@article{CTT100785572,
  author = {K. Miyata and R. Tamamushi and A. Ohkubo and H. Taguchi and K. Seio and T. Santa and M. Sekine},
  title = {Synthesis and properties of a new fluorescent bicyclic 4-N-carbamoyldeoxycytidine derivative},
  journal = {ORGANIC LETTERS},
  year = 2006,
}

@article{CTT100785601,
  author = {H. Taguchi and A. Ohkubo and M. Sekine and K. Seio and H. Kakeya and H. Osada and T. Sasaki},
  title = {Synthesis and biological properties of new phosmidosine analogs having an N-acylsulfamate linkage},
  journal = {NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS},
  year = 2006,
}

@article{CTT100785578,
  author = {M. Sekine and M. Aoyagi and M. Ushioda and A. Ohkubo and K. Seio},
  title = {Chemically stabilized phenylboranylidene groups having a dimethoxytrityl group as a colorimetrically detectable protecting group designed for cis-1,2-diol functions of ribonucleosides in the solid-phase synthesis of m(2)(2,2)G5 ' ppT},
  journal = {JOURNAL OF ORGANIC CHEMISTRY},
  year = 2005,
}

@article{CTT100785586,
  author = {A. Ohkubo and Y. Ezawa and K. Seio and M. Sekine},
  title = {O-selectivity and utility of phosphorylation mediated by phosphite triester intermediates in the N-unprotected phosphoramidite method},
  journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY},
  year = 2004,
}

@article{CTT100505241,
  author = {Akihiro Ohkubo},
  title = {A New Strategy for the Synthesis of Oligodeoxynucleotides Directed toward Perfect O-Selective Internucleotidic Bond Formation without Base Protection},
  journal = {Tetrahedron letters},
  year = 2004,
}

@article{CTT100505243,
  author = {Akihiro Ohkubo},
  title = {O-Selectivity and Utility of Phosphorylation Mediated by a Phosphite Intermediate in N-Unprotected Phosphoramidite Method},
  journal = {Journal of the American Chemical Society},
  year = 2004,
}

@article{CTT100505242,
  author = {Akihiro Ohkubo},
  title = {A New Approach for Pyrophosphate Bond Formation Starting from Phosphoramidite Derivatives by Use of 6-Trifluoromethyl-1-hyroxybenzotriazole-Mediated O-N Phosphoryl Migration},
  journal = {Tetrahedron letters},
  year = 2004,
}

@article{CTT100505245,
  author = {大窪章寛},
  title = {精密ゲノム遺伝子解析法を指向した新技術の展開},
  journal = {蛋白質　核酸　酵素},
  year = 2004,
}

@article{CTT100505244,
  author = {Akihiro Ohkubo},
  title = {Synthesis and Hybridization Affinty of Oligodeoxyribonucleosides Incorporating 4-N-(N-arylcarbamoyl)deoxycytidine Derivatives},
  journal = {Tetrahedron letters},
  year = 2004,
}

@article{CTT100505240,
  author = {Akihiro Ohkubo},
  title = {Proton-Block Strategy for the Synthesus of Oligodeoxynucleotides without Base Protection, Capping Reaction, and P-N Bond Cleavage Reaction},
  journal = {Journal of Organic Chemistry},
  year = 2003,
}

@inproceedings{CTT100854515,
  author = {大窪章寛 and 緒方大介 and 西澤周平},
  title = {三重鎖形成能を向上できる2,6-ジアミノ-1,8-キノリンおよび5'-アミノチミジン誘導体を含むアンチパラレル型三重鎖形成核酸の開発},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100854511,
  author = {大窪章寛},
  title = {次世代の核酸テクノロジーを支える新規核酸合成法の開発},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100854522,
  author = {大窪章寛 and 宮﨑祐宇 and 三宅優 and 池田黄介 and 吉田蒼馬 and 西澤周平 and 伊藤優},
  title = {固相担体に導入した HOBt 誘導体による核酸縮合反応の高効率化},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100854519,
  author = {Akihiro Ohkubo and Shuuhei Nishizawa and Daisuke Ogata and Gaohong Tu and Yu Ito},
  title = {Development of the artificial triplex-forming oligonucleotides containing chemically modified nucleobases or sugar moieties},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100854525,
  author = {大窪章寛 and 久恒一賜 and 宗像功太郎 and 西澤周平 and 伊藤優},
  title = {ビニル基のリボヌクレオシド2´-水酸基高選択的な導入と核酸合成への応用},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100854524,
  author = {大窪章寛 and 伊藤優},
  title = {板状ポーラスガラス上で光分解性保護基を利用した新規核酸合成法の開発},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100854527,
  author = {Akihiro Ohkubo and Yu Miyake and Kousuke Ikeda and Yu Miyazaki and Saaya Akazawa},
  title = {Development of A New Method for Chemical Synthesis of Genomic DNAs},
  booktitle = {},
  year = 2020,
}

@inproceedings{CTT100854528,
  author = {大窪章寛 and 明瀬友輝},
  title = {2-アミノキノリン誘導体を有するアンチパラレル型三重鎖形成 核酸の合成と性質},
  booktitle = {},
  year = 2020,
}

@inproceedings{CTT100785025,
  author = {Shuhei Nishizawa and Tatsuya Ohnishi and Lintaro Watanabe and Takashi Kanamori and Hideya Yuasa and Akihiro Ohkubo},
  title = {Synthesis and properties of triplex-forming oligonucleotides containing modified sugar moieties and nucleobases},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785028,
  author = {Ritsu Hashimoto and Shuhei Nishizawa and Yu Miyake and Takashi Kanamori and Hideya Yuasa and Akihiro Ohkubo},
  title = {Synthesis and properties of cyclic oligonucleotides containing acyl groups at the 5'- and 3'- terminal sites},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100786338,
  author = {金森功吏 and 大西達也 and 渡辺凛太郎 and 西澤周平 and 湯浅英哉 and 大窪章寛},
  title = {糖部および塩基部修飾核酸を用いた三重鎖形成核酸の合成と性質},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785026,
  author = {西澤 周平 and 橋本  律 and 三宅  優 and 金森 功吏 and 湯浅 英哉 and 大窪 章寛},
  title = {アシル基を有する環状オリゴヌクレオチドの合成と性質},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785021,
  author = {渡辺 凜太郎 and 青山 知寛 and 武藤 功甫 and 金森 功吏 and 湯浅 英哉 and 大窪 章寛},
  title = {5'-アミノ-5'-ヒドロキシメチルチミジン誘導体を含むオリゴヌクレオチドの合成と性質},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785024,
  author = {KAEWSOMBOON Tanasak and Kousuke Ikeda and Shuhei Nishizawa and Takashi Kanamori and Hideya Yuasa and Akihiro OHKUBO},
  title = {Synthesis of the modified oligonucleotide containing o-chlorobenzoic acid and its pH dependence of hybridization properties},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785022,
  author = {大西 達也 and 西村 ゆり and 金森 功吏 and 湯浅 英哉 and 大窪 章寛},
  title = {2-アミノキノリン誘導体を含む新規三重鎖形成核酸の合成と性質},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785020,
  author = {西澤 周平 and 橋本 律 and 三宅 優 and 金森 功吏 and 湯浅 英哉 and 大窪 章寛},
  title = {アシル基を有する環状オリゴヌクレオチドの合成と性質},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100781933,
  author = {稲田宏太郎 and 金森功吏 and 大窪章寛 and 小倉俊一郎 and 湯浅英哉},
  title = {GFP色素誘導体を用いた糖鎖受容体のturn-on型蛍光プローブの設計と合成},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100785018,
  author = {Shuhei Nishizawa and Tanasak Kaewsomboon and Takashi Kanamori and Hideya Yuasa and Akihiro Ohkubo},
  title = {Synthesis and Properties of Modified Oligonucleotides Containing Benzoic Acid Derivatives as Nucleobases},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100785019,
  author = {Tomohiro Aoyama and Kosuke Muto and Lintaro Watanabe and Takashi Kanamori and Hideya Yuasa and Akihiro Ohkubo},
  title = {Synthesis and properties of new modified oligonucleotides containing amino groups at the 5ʼ-positions of ribose moieties},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100785014,
  author = {Tanasak Kaewsomboon and Shuhei Nishizawa and Ritsu Hashimoto and Yu Miyake and Takashi Kanamori and Hideya Yuasa and Akihiro Ohkubo},
  title = {Synthesis and Properties of Cyclic Oligonucleotides Containing Acyl Groups},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100785017,
  author = {Takuma Shiraiwa and Kousuke Ikeda and Hirotomo Tanaka and Takashi Kanamori and HIDEYA YUASA and Akihiro Ohkubo},
  title = {Synthesis and properties of 3ʼ-O-protected nucleoside 5ʼ-triphosphate derivatives},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100781928,
  author = {西澤周平 and 橋本律 and 三宅優 and 金森功吏 and 湯浅英哉 and 大窪章寛},
  title = {5’および3’末端にアシル基を有する環状オリゴヌクレオチドの合成と性質},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100781929,
  author = {大西達也 and 西村ゆり and 金森功吏 and 湯浅英哉 and 大窪章寛},
  title = {2-アミノキノリン誘導体を含む三重鎖形成核酸の合成と性質},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100748628,
  author = {Takashi Kanamori and Satoshi Kuwabara and Shun-ichiro Ogura and Akihiro Ohkubo and Hideya  Yuasa},
  title = {In silico screening and synthesis of carbohydrate-modified fluorescent probes for the detection of selectins},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100785015,
  author = {西村 ゆり and Tanasak Kaewsomboon and 金森 功吏 and 湯浅 英哉 and 大窪 章寛},
  title = {イソフタル酸誘導体を有する新規修飾核酸の合成と 性質},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100785016,
  author = {細谷輝 and 金森 功吏 and 湯浅 英哉 and 大窪 章寛},
  title = {U1 snRNA 誘導体の合成},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100748630,
  author = {西澤周平 and 橋本 律 and 金森功吏 and 湯浅 英哉 and 大窪章寛},
  title = {5´および 3´末端にアシル基を有する環状オリゴヌクレオチ ドの合成},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100722445,
  author = {Yoshiaki Masaki and Ryuta Miyasaka and Keishi Yamamoto and Keita Yoshida and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio},
  title = {Deformability analysis of chemically modified RNA and its applicability for estimation of RNA duplex stability},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100724885,
  author = {小田雄貴 and 伊藤比佑吾 and 金森功吏 and 大窪章寛 and 正木慶昭 and 関根光雄 and 清尾康志},
  title = {塩基性条件下不安定なヌクレオシド三リン酸の新規合成法の開発},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100723956,
  author = {Yu Ito and Takashi Kanamori and Yoshiaki Masaki and Akihiro Ohkubo and Kohji Seio and Mitsuo Sekine},
  title = {Synthesis of deoxyuridine derivatives modified with 2,4-diaminopyrimidine moiety for the development of high affinity triplex forming oligonucleotides},
  booktitle = {},
  year = 2015,
}

@misc{CTT100815804,
  author = {大窪章寛},
  title = {精密有機合成を駆使した核酸化学の新展開},
  year = 2010,
}

@misc{CTT100595805,
  author = {Akihiro Ohkubo},
  title = {水酸基高選択的な塩基部無保護ホスホロアミダイト法の開発},
  year = 2004,
}

@misc{CTT100907805,
  author = {大窪章寛 and 久恒一賜},
  title = {２’－ビニルＲＮＡホスホロアミダイトユニットの開発},
  howpublished = {公開特許},
  year = 2023,
  month  = {},
  note   = {特願2022-035609(2022/03/08), 特開2023-130982(2023/09/21)}
}


@misc{CTT100902704,
  author = {大窪章寛 and 伊藤優 and 赤澤紗彩},
  title = {３’－エキソヌクレアーゼを用いた長鎖核酸の精製法},
  howpublished = {公開特許},
  year = 2023,
  month  = {},
  note   = {特願2021-178735(2021/11/01), 特開2023-067467(2023/05/16)}
}


@misc{CTT100884608,
  author = {大窪章寛 and 伊藤優},
  title = {光透過性を向上させたポーラスガラス上での光制御型核酸フロー合成},
  howpublished = {公開特許},
  year = 2022,
  month  = {},
  note   = {特願2021-033892(2021/03/03), 特開2022-134635(2022/09/15)}
}


@misc{CTT100840039,
  author = {大窪章寛 and 池田黄介 and 三宅優},
  title = {核酸合成用固相担体及びそれを用いた核酸の製造方法},
  howpublished = {登録特許},
  year = 2023,
  month  = {},
  note   = {特願2019-031683(2019/02/25), 特開2020-132604(2020/08/31), 特許第7298866号(2023/06/19)}
}


@misc{CTT100690777,
  author = {関根光雄 and 清尾康志 and 大窪章寛 and 角田浩佑 and 正木慶昭 and 金森功吏 and 山田　希 and 山崎一史 and 伊藤比祐吾},
  title = {2'-0-カルバモイル修飾ヌクレオシド三リン酸},
  howpublished = {登録特許},
  year = 2017,
  month  = {},
  note   = {特願2013-152578(2013/07/23), 特開2015-020994(2015/02/02), 特許第6261027号(2017/12/22)}
}


@misc{CTT100593886,
  author = {関根光雄 and 清尾康志 and 大窪章寛 and 角田　浩佑 and 工藤　智美},
  title = {ヌクレオシドトリホスフェート誘導体},
  howpublished = {公開特許},
  year = 2009,
  month  = {},
  note   = {特願2008-057295(2008/03/07), 特開2009-215171(2009/09/24)}
}


@misc{CTT100591483,
  author = {関根光雄 and 清尾康志 and 大窪章寛 and 田中　邦彦},
  title = {オリゴヌクレオチド固定化固相担体},
  howpublished = {公開特許},
  year = 2009,
  month  = {},
  note   = {特願2006-066396(2006/03/10), 特開2009-153381(2009/07/16)}
}


@misc{CTT100577192,
  author = {関根光雄 and 清尾康志 and 大窪章寛 and 坂本　一石 and 佐々見　武志},
  title = {オリゴヌクレオチド誘導体、遺伝子検出用プローブ及びＤＮＡチップ},
  howpublished = {登録特許},
  year = 2011,
  month  = {},
  note   = {特願2007-505962(2006/02/28), 再表2006-093157(2008/08/07), 特許第4882074号(2011/12/16)}
}


@misc{CTT100572772,
  author = {関根光雄 and 清尾康志 and 大窪章寛},
  title = {固体支持体及びDNAチップ},
  howpublished = {公開特許},
  year = 2007,
  month  = {},
  note   = {特願2005-263722(2005/09/12), 特開2007-078399(2007/03/29)}
}


@misc{CTT100572816,
  author = {関根光雄 and 清尾康志 and 大窪章寛 and 粕谷　林太郎},
  title = {トリチル型化合物},
  howpublished = {公開特許},
  year = 2006,
  month  = {},
  note   = {特願2005-066555(2005/03/10), 特開2006-248956(2006/09/21)}
}




@phdthesis{CTT100595805,
  author = {Akihiro Ohkubo},
  title = {水酸基高選択的な塩基部無保護ホスホロアミダイト法の開発},
  school = {東京工業大学},
  year = 2004,
}