@article{CTT100926238, author = {Miki Nagase and Hikaru Ando and Yoshiaki Beppu and Hidetake Kurihara and Souta Oki and Fumimasa Kubo and Kazuki Yamamoto and Takashi Nagase and Shinya Kaname and Yoshihiro Akimoto and Hiroshi Fukuhara and Tatsuo Sakai and Shigehisa Hirose and Nobuhiro Nakamura}, title = {Glomerular Endothelial Cell Receptor Adhesion G-Protein-Coupled Receptor F5 (ADGRF5) and the Integrity of the Glomerular Filtration Barrier}, journal = {Journal of the American Society of Nephrology}, year = 2024, } @article{CTT100875253, author = {Hiroko Matsumoto and Hisako Miyagi and Nobuhiro Nakamura and Yasuhiro Shiga and Toshihiro Ohta and Shoko Fujiwara and Mikio Tsuzuki}, title = {Carbonic anhydrase inhibitor induces otic hair cell apoptosis via an intrinsic pathway and ER stress in zebrafish larvae}, journal = {Toxicology Reports}, year = 2021, } @article{CTT100853891, author = {Anastasia Georgiadi and Valeria Lopez-Salazar and Rabih El- Merahbi and Rhoda Anane Karikari and Xiaochuan Ma and André Mourão and Katarina Klepac and Lea Bühler and Ana Jimena Alfaro and Isabell Kaczmarek and Adam Linford and Madeleen Bosma and Olga Shilkova and Olli Ritvos and Nobuhiro Nakamura and Shigehisa Hirose and Maximilian Lassi and Raffaele Teperino and Juliano Machado and Marcel Scheideler and Arne Dietrich and Arie Geerlof and Annette Feuchtinger and Andreas Blutke and Katrin Fischer and Timo Dirk Müller and Katharina Kessler and Torsten Schöneberg and Doreen Thor and Silke Hornemann and Michael Kruse and Peter Nawroth and Olga Pivovarova-Ramich and Andreas Friedrich Hermann Pfeiffer and Michael Sattler and Matthias Blüher and Stephan Herzig}, title = {Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.}, journal = {Nature communications}, year = 2021, } @article{CTT100853893, author = {Doshun Ito and Hinata Kawamura and Akira Oikawa and Yuta Ihara and Toshio Shibata and Nobuhiro Nakamura and Tsunaki Asano and Shun-Ichiro Kawabata and Takashi Suzuki and Shinji Masuda}, title = {ppGpp functions as an alarmone in metazoa}, journal = {Communications Biology}, year = 2020, } @article{CTT100807735, author = {Kubo F and Ariestanti donna maretta and Oki Souta and Taku Fukuzawa and Demizu R and Sato Tomoya and Rahmaningsih Mara Sabirin and Hirose shigehisa and Nobuhiro Nakamura}, title = {Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells.}, journal = {Respiratory Research}, year = 2019, } @article{CTT100774347, author = {Hiroko Matsumoto and Shoko Fujiwara and Hisako Miyagi and Nobuhiro Nakamura and Yasuhiro Shiga and Toshihiro Ohta and Mikio Tsuzuki}, title = {Carbonic Anhydrase Inhibitors Induce Developmental Toxicity During Zebrafish Embryogenesis, Especially in the Inner Ear}, journal = {Marine Biotechnology}, year = 2017, } @article{CTT100745047, author = {Harada K and Masako Kato and Nobuhiro Nakamura}, title = {USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.}, journal = {Int. J. Mol. Sci.}, year = 2016, } @article{CTT100702013, author = {Miyagi H and Nag K and Sultana N and Munakata K and Hirose S and Nakamura N}, title = {Characterization of the zebrafish cx36.7 gene promoter: its regulation of cardiac-specific expression and skeletal muscle-specific repression}, journal = {Gene}, year = 2016, } @article{CTT100711043, author = {Donna Maretta Ariestanti and Hikaru Ando and SHIGEHISA HIROSE and Nobuhiro Nakamura}, title = {Targeted disruption of Ig-Hepta/Gpr116 causes emphysema-like symptoms that are associated with alveolar macrophage activation}, journal = {Journal of Biological Chemistry}, year = 2015, } @article{CTT100673922, author = {Kakon Nag and Naznin Sultana and Akira Kato and A Dranik and Nobuhiro Nakamura and Koichi Kutsuzawa and Shigehisa Hirose and Toshihiro Akaike}, title = {Ligand-induced internalization, recycling, and resensitization of adrenomedullin receptors depend not on CLR or RAMP alone but on the receptor complex as a whole}, journal = {Gen Comp Endocrinol}, year = 2015, } @article{CTT100681418, author = {Nakamura N and Harada K and Kato M and Hirose S}, title = {Ubiquitin-specific protease 19 regulates the stability of the E3 ubiquitin ligase MARCH6}, journal = {Experimental Cell Research}, year = 2014, } @article{CTT100681435, author = {Fukuzawa T and Ishida J and Kato A and Ichinose T and Ariestanti DM and Takahashi Tomoya and Ito Kunitoshi and Abe J and Suzuki T and Wakana S and Fukamizu A and Nobuhiro Nakamura and hirose shige}, title = {Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein D.}, journal = {PLOS One}, year = 2013, } @article{CTT100681433, author = {Ito yusuke and Kobayashi S and Nobuhiro Nakamura and Esaki M and Miyagi H and Hoshijima K and Hirose S}, title = {Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake}, journal = {Front. Physio.}, year = 2013, } @article{CTT100681432, author = {Zhao B and Ito Kunitoshi and Iyengar PV and Hirose S and Nobuhiro Nakamura}, title = {MARCH7 E3 ubiquitin ligase is highly expressed in developing spermatids of rats and its possible involvement in head and tail formation}, journal = {Histochem. Cell Biol}, year = 2013, } @article{CTT100653200, author = {Fukuda H and Hirata T and Nakamura N and Kato A and Kawahara K and Wakabayashi S and Chang MH and Romero MF and Hirose S.}, title = {Identification and properties of a novel variant of NBC4 (Na(+)/HCO(3)- co-transporter 4) that is predominantly expressed in the choroid plexus.}, journal = {Biochem J}, year = 2013, } @article{CTT100681431, author = {Han SO and Xiao K and Kim J and Wu JH and Wisler JW and Nobuhiro Nakamura and Freedman NJ and Shenoy SK}, title = {MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β2-adrenergic receptors}, journal = {J Cell Biol}, year = 2012, } @article{CTT100681430, author = {Yogo K and Tojima H and Ohno JY and Ogawa T and Nobuhiro Nakamura and SHIGEHISA HIROSE and Takeya T and Kohsaka T}, title = {Identification of SAMT family proteins as substrates of MARCH11 in mouse spermatids}, journal = {Histochem. Cell Biol.}, year = 2012, } @article{CTT100681427, author = {Iyengar PV and Hirota T and hirose S and Nobuhiro Nakamura}, title = {Membrane-associated RING-CH 10 (MARCH10 Protein) is a microtubule-associated E3 ubiquitin ligase of the spermatid flagella}, journal = {J. Biol. Chem.}, year = 2011, } @article{CTT100616877, author = {Kaori Saito and Nobuhiro Nakamura and Yusuke Ito and Kazuyuki Hoshijima and Masahiro Esaki and Boqiang Zhao and Shigehisa Hirose}, title = {Identification of zebrafish FXYD11a protein that is highly expressed in ion-transporting epithelium of the gill and skin and its possible role in ion homeostasis}, journal = {Frontiers in Physiology}, year = 2010, } @article{CTT100592829, author = {Nakada T and Westhoff CM and Yoko Yamaguchi and Susumu Hyodo and X Li and Takayuki Muro and Kato A and Nakamura N and Hirose S.}, title = {Rhesus glycoprotein p2 (Rhp2) is a novel member of the Rh family of ammonia transporters highly expressed in shark kidney}, journal = {J. Biol. Chem.}, year = 2010, } @article{CTT100590637, author = {Aihara Takeshi and Nobuhiro Nakamura and Shinji Honda and SHIGEHISA HIROSE}, title = {A novel potential role for gametogenetin-binding protein 1 (GGNBP1) in mitochondrial morphogenesis during spermatogenesis in mice.}, journal = {Biology of Reproduction}, year = 2009, } @article{CTT100585520, author = {Masahiro Esaki and Kazuyuki Hoshijima and Nobuhiro Nakamura and Keijiro Munakata and Mikiko Tanaka and Kayoko Ookata and Kazuhide Asakawa and Koichi Kawakami and Weiyi Wang and Eric S. Weinberg}, title = {Mechanism of development of ionocytes rich in vacuolar-type H+-ATPase in the skin of zebrafish larvae}, journal = {Dev. Biol.}, year = 2009, } @article{CTT100549859, author = {Nobuhiro Nakamura and Shigehisa Hirose}, title = {Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane}, journal = {Mol. Biol. Cell}, year = 2008, } @article{CTT100548544, author = {Morokuma Y and Nobuhiro Nakamura and Akira Kato and Notoya M and yoko yamamoto and Sakai Y and 福田英一 and Yamashina S and Hirata Y and SHIGEHISA HIROSE}, title = {MARCH-XI, a novel transmembrane ubiquitin ligase implicated in ubiquitin-dependent protein sorting in developing spermatids}, journal = {J. Biol. Chem.}, year = 2007, } @article{CTT100681426, author = {Nobuhiro Nakamura and Yasuo Kimura and Masaki Tokuda and Shinji Honda and Shigehisa Hirose}, title = {MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology}, journal = {EMBO Rep.}, year = 2006, } @article{CTT100540624, author = {Tateno, T. and Nakamura N. and Hirata Y. and SHIGEHISA HIROSE}, title = {Role of C-terminus of Kir7.1 potassium channel in cell-surface expression}, journal = {Cell Biol. Int.}, year = 2006, } @article{CTT100540459, author = {H Fukuda and N Nakamura and S Hirose}, title = {MARCH-III is a novel component of endosomes with properties similar to those of MARCH-II}, journal = {J Biochem}, year = 2006, } @article{CTT100681428, author = {Nobuhiro Nakamura and Fukuda H and Kato A and Hirose S}, title = {MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking}, journal = {Molecular Biology of the Cell}, year = 2005, } @article{CTT100681425, author = {Y Suzuki and Y Yasuoka and T Shimohama and M Nishikitani and N Nakamura and S Hirose and K Kawahara}, title = {Expression of the K+ channel Kir7.1 in developing rat kidney: role in K+ excretion}, journal = {Kidney Int}, year = 2003, } @article{CTT100681420, author = {K Miyamoto and N Nakamura and M Kashiwagi and S Honda and A Kato and S Hasegawa and Y Takei and S Hirose}, title = {RING finger, B-box, and coiled-coil (RBCC) protein expression in branchial epithelial cells of Japanese eel, Anguilla japonica}, journal = {Eur. J. Biochem}, year = 2002, } @article{CTT100681421, author = {K Ookata and A Tojo and Y Suzuki and N Nakamura and K Kimura and CS Wilcox and S Hirose}, title = {Localization of inward rectifier potassium channel Kir7.1 in the basal membrane of distal nephron}, journal = {J. Am. Soc. Nephrol}, year = 2000, } @article{CTT100681424, author = {N Nakamura and Y Suzuki and Y Ikeda Y and M Notoya and S Hirose}, title = {Complex structure and regulation of expression of the rat gene for inward rectifier potassium channel Kir7.1}, journal = {J. Biol. Chem}, year = 2000, } @article{CTT100481762, author = {N Nakamura and Y Suzuki and H Sakuta and K Ookata and K Kawahara and S Hirose}, title = {Inwardly rectifying potassium channel Kir7.1 is highly expressed in the thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase}, journal = {Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels}, year = 2000, } @article{CTT100681423, author = {N Nakamura and Y Suzuki and H Sakuta and K Ookata and K Kawahara and S Hirose}, title = {Inwardly rectifying potassium channel Kir7.1 is highly expressed in the thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase}, journal = {Biochem. J}, year = 1999, } @article{CTT100681422, author = {Y Suzuki Y and M Itakura and M Kashiwagi and N Nakamura and T Matsuki and H Sakuta and N Naito and K Takano and T Fujita and S Hirose}, title = {Identification by differential display of a hypertonicity-inducible inward rectifier pottasium channel highly expressed in chloride cells}, journal = {J. Biol. Chem}, year = 1999, } @inproceedings{CTT100917185, author = {Kazuki Yamamoto and Masako Kato and Yoshiaki Beppu and 長瀬美樹 and Nobuhiro Nakamura}, title = {Mechanosensory activation of ADGRF5 and its effect on KLF2 gene expression}, booktitle = {}, year = 2023, } @inproceedings{CTT100917184, author = {Shiyota Yamada and Nobuhiro Nakamura}, title = {Effects of cigarette smoke extracts on the expression of the G protein-coupled receptor Adgrf5 and KLF2 in mouse pulmonary endothelial cells}, booktitle = {}, year = 2023, } @inproceedings{CTT100917189, author = {中村 信大 and 山田 翔太 and 山本 一輝 and 長瀬美樹}, title = {免疫制御を担う新規受容体分子の肺血管内皮細胞のニコチン応答と炎症応答に及ぼす影響}, booktitle = {}, year = 2023, } @inproceedings{CTT100894894, author = {山田 翔太 and 中村信大}, title = {タバコ煙抽出液処理によるマウス肺血管内皮細胞におけるGタンパク質共役型受容体Adgrf5の発現変動}, booktitle = {}, year = 2022, } @inproceedings{CTT100883498, author = {Nobuhiro Nakamura}, title = {Targeted disruption of GPR116 (ADGRF5) impairs the integrity of the glomerular filtration barrier in mice.}, booktitle = {}, year = 2022, } @inproceedings{CTT100894895, author = {中村 信大 and 山田 翔太}, title = {細胞外マトリックス異常を伴うノックアウトマウスを用いたGPCR分子の新機能解明を目指した研究}, booktitle = {}, year = 2022, } @inproceedings{CTT100875254, author = {Takuto Anno and Masako Kato and Eiichi Kikuchi and Nobuhiro Nakamura}, title = {Identification of MARCH2 as a Ubiquitinating Enzyme for Syntaxin-6 and the Effect of Ubiquitination onSubcellular Localization of Syntaxin-6}, booktitle = {}, year = 2021, } @inproceedings{CTT100875259, author = {松本 聖慈 and 加藤 真子 and 中村 信大}, title = {A549細胞におけるUSP30-AS1の発現制御とUSP30の発現への影響の解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100836147, author = {菊地 英一 and 加藤 真子 and 安濃 拓人 and 安濃 卓人 and 中村 信大}, title = {E3ユビキチンリガーゼMARCH2によるSyntaxin-6のユビキチン化の解析}, booktitle = {}, year = 2020, } @inproceedings{CTT100836144, author = {別府 義彬 and 長瀬 美樹 and 安東 輝 and 栗原 秀剛 and 久保 文雅 and 沖 颯太 and 坂井 健雄 and 広瀬 茂久 and 中村 信大}, title = {Gタンパク質共役型受容体Adgrf5の欠損による腎糸球体濾過障壁の構造異常}, booktitle = {}, year = 2020, } @inproceedings{CTT100836146, author = {永沢 佑陽 and 加藤 真子 and 中村 信大}, title = {ヒトGタンパク質共役型受容体ADGRF5のタンパク質発現調節機構の解析}, booktitle = {}, year = 2020, } @inproceedings{CTT100836153, author = {Tomoya Sato and Masako Kato and Fumimasa Kubo and Nobuhiro Nakamura}, title = {Intracellular signaling Mechanism of G-protein coupled receptor ADGRF5}, booktitle = {}, year = 2018, } @inproceedings{CTT100836150, author = {久保 文雅 and Donna Ariestanti and 沖 颯太 and 福澤拓 and 出水 遼太郎 and 佐藤朋哉 and Rahmaningsih Sabirin and 広瀬茂久 and 中村 信大}, title = {Gタンパク質共役型受容体ADGRF5の欠損は肺血管内皮細胞における炎症性分子の発現と喘息に似た表現圭を誘導する}, booktitle = {}, year = 2018, } @inproceedings{CTT100836154, author = {久保 文雅 and Donna Ariestanti and 沖 颯太 and Rahmaningsih Sabirin and 出水 遼太郎 and 中村 信大}, title = {Adgrf5欠損マウスは気管支喘息および肺線維症様の表現型を現す}, booktitle = {}, year = 2017, } @inproceedings{CTT100836155, author = {Fumimasa Kubo and Donna Maretta Ariestanti and Souta Oki and Rahmaningsih Mara Sabirin and 出水 遼太郎 and Nobuhiro Nakamura}, title = {Adgrf5 deficient mice exhibit bronchial asthma- and fibrosis-like phenotypes}, booktitle = {}, year = 2017, } @inproceedings{CTT100774337, author = {Xiaochuan Ma et al. and Nobuhiro Nakamura and Hirose S and Anastasia Georgiadi and Stephan Herzig}, title = {FNDC4 Promotes Brown-Like Adipocyte Formation and Glucose Clearance via an Orphan G-protein Coupled Receptor}, booktitle = {DIABETES}, year = 2017, } @inproceedings{CTT100745165, author = {A Georgiadi and S Seaman and O Ritvos and BS Croix and Nobuhiro Nakamura and SHIGEHISA HIROSE and M Scheideler and S Herzig and PA Böstrom}, title = {Fndc4, a highly identical ortholog of Irisin binds and activates a novel orphan receptor G-protein coupled receptor}, booktitle = {Diabetologie und Stoffwechsel}, year = 2016, } @inproceedings{CTT100802387, author = {Fukuda, Hidekazu and Hirata, Taku and Nobuhiro Nakamura and Kawahara, Katsumasa and Hirose, Shigehisa}, title = {Characterization of a novel variant of the Na+/HCO3- cotransporter 4 (NBC 4) expressed in rat choroid plexus}, booktitle = {JOURNAL OF PHYSIOLOGICAL SCIENCES}, year = 2013, } @inproceedings{CTT100853894, author = {Fukuda, Hidekazu and Hirata, Taku and Nobuhiro Nakamura and Kawahara, Katsumasa and Hirose, Shigehisa}, title = {Characterization of a novel variant of the Na+/HCO3- cotransporter 4 (NBC 4) expressed in rat choroid plexus}, booktitle = {Journal of Physiological Sciences}, year = 2013, } @inproceedings{CTT100853896, author = {Ito, Yusuke and Kobayashi, Sayako and Esaki, Masahiro and Nobuhiro Nakamura and Hoshijima, Kazuyuki and Hirose, Shigehisa}, title = {LOCALIZATION OF CARBONIC ANHYDRASES IN MITOCHONDRIA-RICH CELLS OF ZEBRAFISH}, booktitle = {Journal of Physiological Sciences}, year = 2009, } @inproceedings{CTT100853897, author = {Nakamura Nobuhiro and Fukuda Hidekazu and Kato Akira and Hirose Shigehisa}, title = {Identification of a novel syntaxin-6-binding protein}, booktitle = {Cell Structure and Function}, year = 2005, } @inproceedings{CTT100853898, author = {Fukuda Hidekazu and Hirata Taku and Nakamura Nobuhiro and Wakabayashi S and Romero MF and Hirose Shigehisa}, title = {Molecular characterization and immunohistochemical localization of a bicarbonate transporter highly and predominantly expressed in rat choroid plexus epithelial cells}, booktitle = {Faseb Journal}, year = 2005, } @inproceedings{CTT100400050, author = {H Fukuda and N Nakamura and A Kato and S Hirose}, title = {Kdg2, a novel multidomain protein involved in the regulation of recycling endosomal trafficking.}, booktitle = {Mol. Cell. Proteomics}, year = 2003, } @inproceedings{CTT100488875, author = {Nakamura N and 福田英一 and Ikeda Y and SHIGEHISA HIROSE}, title = {Kdg1, a novel RING-finger membrane protein that localizes in the recycling endosome compartment.}, booktitle = {Mol. Biol. Cell}, year = 2002, } @inproceedings{CTT100481761, author = {Y Suzuki and N Nakamura and H Sakuta and KTakano and T Fujita and S Hirose}, title = {Cloning and properties of a hypertonicity-inducible inward rectifier K+ channel from euryhaline eels}, booktitle = {Cell Volume Regulation}, year = 1998, } @misc{CTT100853892, author = {Nobuhiro Nakamura}, title = {Cigarette smoke attenuates p300‐mediated Nrf2 acetylation in macrophages: Is stabilizing Nrf2 enough to halt COPD progression?}, year = 2021, } @misc{CTT100774345, author = {Nobuhiro Nakamura}, title = {Ubiquitin System}, year = 2018, } @misc{CTT100681436, author = {Sultana N and Nobuhiro Nakamura and Hirose Shige and Kutsuzawa K and Akaike T and Nag K}, title = {Congenital heart disease and biotechnology: Connecting by connexin}, year = 2014, } @misc{CTT100681434, author = {Nobuhiro Nakamura}, title = {Ubiquitination regulates the morphogenesis and function of sperm organelles}, year = 2013, } @misc{CTT100681429, author = {Nobuhiro Nakamura}, title = {The role of the transmembrane RING finger proteins in cellular and organelle function}, year = 2011, } @misc{CTT100596053, author = {Nobuhiro Nakamura}, title = {Kdg1, a Membrane Protein of the Recycling Endosome with Ubiquitin Ligase Activity, Promotes Degradation of the Transferrin Receptor}, year = 2003, } @phdthesis{CTT100596053, author = {Nobuhiro Nakamura}, title = {Kdg1, a Membrane Protein of the Recycling Endosome with Ubiquitin Ligase Activity, Promotes Degradation of the Transferrin Receptor}, school = {東京工業大学}, year = 2003, }