@book{CTT100691757, author = {畠山士 and 半田宏}, title = {ナノ融合による先進バイオデバイス}, publisher = {シーエムシー出版}, year = 2011, } @book{CTT100691758, author = {畠山士 and 加部泰明 and 半田宏}, title = {ナノ粒子分散系の基礎と応用}, publisher = {シーエムシー出版}, year = 2011, } @book{CTT100614930, author = {半田宏 and 畠山士}, title = {コアシェル微粒子の設計・合成技術・応用の展開}, publisher = {シーエムシー出版}, year = 2010, } @book{CTT100614921, author = {Yasuaki Kabe and Mamoru Hatakeyama and Satoshi Sakamoto and KOSUKE NISHIO and Hiroshi Handa}, title = {Novel Applications of Affinity Beads}, publisher = {Jhon Wiley & Sons. Inc.}, year = 2009, } @book{CTT100527656, author = {畠山士 and 加部泰明 and 半田宏}, title = {『ナノ粒子分散系の科学と技術』シーエムシー出版・医薬品分野における分散技術}, publisher = {シーエムシー出版}, year = 2006, } @article{CTT100723498, author = {Masa-aki Kawano and Koji Doi and Hajime Fukuda and Yoshinori Kita and Imai Kensuke and Takamasa Inoue and Teruya Enomoto and Masanori Matsui and Mamoru Hatakeyama and Yuki Yamaguchi and Hiroshi Handa}, title = {SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes}, journal = {Biotechnol. Rep.}, year = 2015, } @article{CTT100691776, author = {Shuji Iida and Kensuke Imai and Sachiko Matsuda and Osamu Itano and Mamoru Hatakeyama and Satoshi Sakamoto and Daisuke Kokuryo and Koji Okabayashi and Takashi Endo and Yoshiyuki Ishii and Hirotoshi Hasegawa and Ichio Aoki and Hiroshi Handa and Yuko Kitagawa}, title = {In vivo identification of sentinel lymph nodes using MRI and size-controlled and monodispersed magnetite nanoparticles}, journal = {Journal of Magnetic Resonance Imaging}, year = 2013, } @article{CTT100691778, author = {Teruya Enomoto and Masaaki Kawano and Hajime Fukuda and Wataru Sawada and Takamasa Inoue and Kok Chee Haw and Yoshinori Kita and Satoshi Sakamoto and Takeshi Imai and Mamoru Hatakeyama and Shigeyoshi Saito and Adarsh Sandhu and Masanori Matsui and Ichio Aoki and Hiroshi Handa}, title = {Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1}, journal = {Journal of Biotechnology}, year = 2013, } @article{CTT100723504, author = {Teruya Enomoto and Masa-aki Kawano and Hajime Fukuda and Wataru Sawada and Takamasa Inoue and Kok Chee Haw and Yoshinori Kita and Satoshi Sakamoto and Yuki Yamaguchi and Takeshi Imai and Mamoru Hatakeyama and Shigeyoshi Saito and Adarsh Sandhu and Masanori Matsui and Ichio Aoki and Hiroshi Handa}, title = {Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1}, journal = {J. Biotechnol.}, year = 2013, } @article{CTT100691791, author = {Satoshi Sakamoto and Mamoru Hatakeyama and Takumi Ito and Hiroshi Handa}, title = {Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound}, journal = {Bioorganic & Medicinal Chemistry}, year = 2012, } @article{CTT100691797, author = {Mamoru Hatakeyama and Hiroshi Kishi and Yoshinori Kita and Kensuke Imai and Kosuke Nishio and Satoki Karasawa and Yuka Masaike and Satoshi Sakamoto and Adarsh Sandhu and Akihiro Tanimoto and Tatsuya Gomi and Eiichi Kohda and Masanori Abe and Hiroshi Handa}, title = {A two-step ligand exchange reaction generates highly water-dispersed magnetic nanoparticles for biomedical applications}, journal = {Journal of Materials Chemistry}, year = 2011, } @article{CTT100691811, author = {Masaki Hiramoto and Naoya Maekawa and Takeshi Kuge and Fumiaki Ayabe and Atsushi Watanabe and Yuka Masaike and Mamoru Hatakeyama and Hiroshi Handa and Takeshi Imai}, title = {High-performance affinity chromatography method for identification of L-arginine interacting factors using magnetic nanobeads}, journal = {Biomedical Chromatography}, year = 2010, } @article{CTT100691815, author = {Aiko Tominaga and Hideki Sugawara and Toshitaka Futagawa and Kazuhiko Inoue and Kazuki Sasaki and Naoto Minamino and Mamoru Hatakeyama and Hiroshi Handa and Atsuro Miyata}, title = {Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene}, journal = {Genes to Cells}, year = 2010, } @article{CTT100597656, author = {Satoshi Sakamoto and Yasuaki Kabe and Mamoru Hatakeyama and Yuki Yamaguchi and Hiroshi Handa}, title = {Development and application of high-performance affinity beads: toward chemical biology and drug discovery}, journal = {Chem. Rec.}, year = 2009, } @article{CTT100525670, author = {畠山士 and 西尾広介 and 中村光裕 and 坂本聡 and 加部泰明 and 和田忠士 and 半田宏}, title = {アフィニティ精製用担体としての高分子微粒子}, journal = {社団法人高分子学会、高分子論文集}, year = 2007, } @article{CTT100561138, author = {Hitoshi Uga and Chikanori Kuramori and Akiko Ohta and Yasunori Tsuboi and Hiroshi Tanaka and Mamoru Hatakeyama and Yuki Yamaguchi and Masahiro Kizaki and Takashi Takahashi and Hiroshi Handa}, title = {A new mechanism of methotrexate action revealed by target screening with affinity beads}, journal = {Mol. Pharmacol.}, year = 2006, } @article{CTT100542384, author = {M. Hasegawa and H. Ohno and H. Tanaka and M. Hatakeyama and H. Kawaguchi and T. Takahashi and H. Handa}, title = {Affinity identification of δ-opioid receptors using latex particles.}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2006, } @article{CTT100525056, author = {H. Uga and C. Kuramori and A. Ohta and Y. Tsuboi and H. Tanaka and M. Hatakeyama and Y. Yamaguchi and T. Takahashi and M. Kizaki and H. Handa.}, title = {A New Mechanism of Methotrexate Action Revealed by Target Screening with Affinity Beads}, journal = {MOLECULAR PHARMACOLOGY}, year = 2006, } @article{CTT100409898, author = {S. Ohba and M. Hatakeyama and H. Handa and H. Kawaguchi}, title = {Development of Polymer Latex Particles for Selective Cleavage of Mismatched DNA and Their Application for DNA Diagnosis.}, journal = {Bioconjugate Chemistry}, year = 2005, } @article{CTT100542386, author = {Y. Ohtsu and R. Ohba and Y. Imamura and M. Kobayashi and H. Hatori and T. Zenkoh and M. Hatakeyama and T. Manabe and M. Hino and Y. Yamaguchi and K. Kataoka and H. Kawaguchi and H. Watanabe and H. Handa}, title = {Selective ligand purification using high-performance affinity beads.}, journal = {Analytical Biochemistry}, year = 2005, } @article{CTT100561509, author = {Tatsuya Zenkoh and Hidetaka Hatori and Hiroshi Tanaka and Makoto Hasegawa and Mamoru Hatakeyama and Yasuaki Kabe and Hiroyuki Setoi and Haruma Kawaguchi and Hiroshi Handa and Takashi Takashi}, title = {Design and Synthesis of a Solid-Supported FR225659 Derivative for Its Receptor Screening}, journal = {Organic Letters}, year = 2004, } @article{CTT100409901, author = {S. Tsubouchi and K. Nishio and M. Ikeda and H. Narimatsu and M. Hatakeyama and N.Gokon and H. Handa}, title = {Polymer coating of ferrite nanoparticles by using “connector” chemical compounds.}, journal = {International Conference on Ferrites (ICF-9)}, year = 2004, } @article{CTT100409902, author = {K. Nishio and M. Hasegawa and M. Ikeda and H. Narimatsu and Y. Hase and Y. Ogura and N. Gokon and S. Tsubouchi and M. Hatakeyama and M.Abe and H. Handa}, title = {Synthesis of monodisperse ferrite nanoparticles coated with polyacrylic acid (PAA).}, journal = {Transactions of the Materials Research Society of Japan}, year = 2004, } @article{CTT100409905, author = {T. Tomohiro and J. Sawada and C. Sawa and H. Nakura and S. Yoshida and M. Kodaka and M. Hatakeyama and H. Kawaguchi and H. Handa and H. Okuno}, title = {Total Analysis and Purification of Cellular Proteins Binding to Cisplatin-Damaged DNA Using Submicron Beads.}, journal = {Bioconjugate Chemistry}, year = 2002, } @article{CTT100409904, author = {M. Hiramoto and N. Shimizu and T. Nishi and D. Shima and S. Aizawa and H. Tanaka and M. Hatakeyama and H. Kawaguchi and H. Handa}, title = {High-performance affinity beads for identifying anti-NF-kappa-B drug receptors.}, journal = {Methods in Enzymology}, year = 2002, } @article{CTT100409906, author = {K. Kobayashi and M. Hatakeyama and Y. Toshima and Y. Tamada}, title = {Response by bylayer membranes containing the labial palpus of fly to stimulative substances.}, journal = {Molecular Crystals and Liquid Crystals}, year = 2001, } @article{CTT100542387, author = {N. Shimizu and K. Sugimoto and J. Tang and T. Nishi and I. Sato and M. Hiramoto and S. Aizawa and M. Hatakeyama and R. Ohba and H. Hatori and T. Yoshikawa and F. Suzuki and A. Oomori and H. Tanaka and H. Kawaguchi and H. Watanabe and H. Handa}, title = {High-performance affinity beads for identifying drug receptors.}, journal = {Nature Biotechnology}, year = 2000, } @article{CTT100409908, author = {M. Hatakeyama and S. Iwato and K. Hanashita and K. Nakamura and K. Fujimoto and H. Kawaguchi}, title = {DNA-carrying latex particles 3. Detection of point mutant DNA using an indirect labeled probe.}, journal = {Colloids and Surfaces A: Physicochemical and Engineering Aspects}, year = 1999, } @article{CTT100409911, author = {M. Hatakeyama and Y. Ogura and J. Sawada and K. Fujimoto and H. Handa and K. Kawaguchi}, title = {Preparation of dimerized polypeptide-carrying microspheres and purification of specific proteins bound to these micorspheres.}, journal = {Colloids and Surfaces B: Biointerfaces}, year = 1998, } @article{CTT100409909, author = {M. Hatakeyama and K. Nakamura and S. Iwato and H. Handa and K. Fujimoto and H. Kawaguchi}, title = {DNA-carrying latex particles 2. Distinction of normal and point mutant DNA using S1 nuclease.}, journal = {Colloids and Surfaces B: Biointerfaces}, year = 1998, } @article{CTT100409910, author = {M. Hatakeyama and S. Iwato and K. Fujimoto and H. Handa and H. Kawaguchi}, title = {DNA-carrying latex particles 1. Separation of normal and point mutant DNAs according to the difference in hybridization efficiency.}, journal = {Colloids and Surfaces B: Biointerfaces}, year = 1998, } @article{CTT100409912, author = {H. Kawaguchi and M. Hatakeyama and S. Iwato and K.Fujimoto and H. Handa}, title = {Affinity latex for DNA diagnosis.}, journal = {Advances in Polymeric Biomaterials Science}, year = 1997, } @article{CTT100409913, author = {T. Imai and Y. Sumi and M. Hatakeyama and K. Fujimoto and H. Kawaguchi and N. Hayashida and K. Shiozaki and K. Terada and H. Yajima and H. Handa}, title = {Selective isolation of DNA and RNA using single-stranded DNA affinity latex particles.}, journal = {Journal of Colloid and Interface Science}, year = 1996, } @article{CTT100409914, author = {T. Shiroya and M. Hatakeyama and K. Fujimoto and H. Watanabe and T. Wada and T. Imai and H. Kawaguchi and H. Handa}, title = {Purification of transcription factor IIA using yeast TATA-binding protein affinity latex particles.}, journal = {International Journal of bio-chromatography}, year = 1995, } @inproceedings{CTT100533670, author = {畠山士 and 西尾広介 and 中村光裕 and 坂本聡 and 関口健司 and 羽生尚広 and 加部泰明 and 和田忠士 and 半田宏}, title = {アフィニティ精製用担体としての高分子微粒子}, booktitle = {社団法人高分子学会}, year = 2007, } @inproceedings{CTT100533669, author = {川 和紀 and 嶋津 隆一 and 畠山 士 and 阿部 正紀 and 半田 宏 and 松下 伸広 and 吉村 昌弘}, title = {水熱法で成長させたフェライト粒子のポリマー被覆と磁気特性}, booktitle = {粉体粉末冶金協会}, year = 2006, } @inproceedings{CTT100528469, author = {西尾広介 and 政池由佳 and 郷右近展之 and 壷内信吾 and 池田森人 and 成松宏樹 and 畠山士 and 坂本聡 and 阿部正紀 and 半田宏}, title = {ナノ磁性アフィニティビーズの構築}, booktitle = {高分子ミクロスフェア討論会編集委員会}, year = 2006, } @inproceedings{CTT100525055, author = {K. Nishio and Y. Masaike and N. Gokon and S. Tsubouchi and M. Ikeda and H. Narimatsu and M. Hatakeyama and S. Sakamoto and N. Hanyu and M. Abe and H. Handa.}, title = {Development of Novel Magnetic Nanobeads for Bio-Screening}, booktitle = {The Magnetics Society of Japan}, year = 2006, } @inproceedings{CTT100528464, author = {田中浩士 and 善光龍哉 and 羽鳥英孝 and 小林幹央 and 長谷川慎 and 畠山士 and 瀬戸井宏行 and 日野資弘 and 川口春馬 and 半田 宏 and 高橋孝志}, title = {糖新生阻害剤FR225659のライブラリー構築とその標的蛋白質の探索}, booktitle = {Combinatorial Chemistry研究会}, year = 2004, } @inproceedings{CTT100528461, author = {大場慎介 and 畠山士 and 半田宏 and 川口春馬}, title = {アフィニティラテックスを用いたミスマッチDNA識別}, booktitle = {日本バイオマテリアル学会}, year = 2002, } @inproceedings{CTT100528460, author = {涌井渉 and 畠山士 and 永井康彦 and 七里徳重 and 川口春馬}, title = {磁性体微粒子のその場生成をともなう重合による複合粒子の作製}, booktitle = {高分子学会}, year = 2001, } @inproceedings{CTT100528457, author = {小林一稔 and 畠山士 and 都島良行 and 玉田靖}, title = {ハエの舌弁組織を含有したリポソームの刺激応答評価}, booktitle = {高分子学会}, year = 2000, } @inproceedings{CTT100528455, author = {吉宗亜弓 and 畠山士 and 藤本啓二 and 半田宏 and 川口春馬}, title = {アフィニティラテックスにおけるポリエチレングリコール系スペーサーの検討}, booktitle = {高分子年次大会}, year = 2000, } @inproceedings{CTT100409917, author = {M. Hatakeyama and K. Nakamura and K. Hanashita and H. Handa and K. Fujimoto and H. Kawaguchi}, title = {Development of DNA affinity latex for genetic diagnosis.}, booktitle = {The 4th Asian Symposium on Biomedical Materials}, year = 1999, } @inproceedings{CTT100528451, author = {中村恭子 and 畠山士 and 藤本啓二 and 川口春馬}, title = {DNA固定ラテックスとS1ヌクレアーゼを用いた点変異DNAの識別}, booktitle = {高分子学会}, year = 1998, } @inproceedings{CTT100528448, author = {畠山士 and 中村恭子 and 花下香子 and 藤本啓二 and 半田宏 and 川口春馬}, title = {遺伝子診断のためのDNAアフィニティラテックスの改良}, booktitle = {高分子学会}, year = 1998, } @inproceedings{CTT100528441, author = {畠山士 and 岩戸聡子 and 中村恭子 and 藤本啓二 and 半田宏 and 川口春馬}, title = {DNA固定ラテックス粒子上での点変異遺伝子の識別}, booktitle = {高分子学会}, year = 1997, } @inproceedings{CTT100528436, author = {畠山士 and 岩戸聡子 and 中村恭子 and 藤本啓二 and 半田宏 and 川口春馬}, title = {高分子ミクロスフェアを用いた点変異DNAの識別}, booktitle = {高分子学会}, year = 1997, } @inproceedings{CTT100528431, author = {畠山士 and 中村恭子 and 岩戸聡子 and 藤本啓二 and 半田宏 and 川口春馬}, title = {DNA一本鎖切断酵素を用いた遺伝子システムの構築}, booktitle = {高分子学会}, year = 1997, } @inproceedings{CTT100528429, author = {岩戸聡子 and 畠山士 and 藤本啓二 and 半田宏 and 川口春馬}, title = {DNA固定ラテックスを用いた点変異検出システムの構築}, booktitle = {高分子学会}, year = 1997, } @inproceedings{CTT100409919, author = {M. Hatakeyama and H. Handa and K. Fujimoto and H. Kawaguchi}, title = {Preparation of dimerized polypeptide-carrying microspheres and purification of specific protein bound to these microspheres.}, booktitle = {The 3rd Far-Eastern Symposium on Biomedical Materials}, year = 1997, } @inproceedings{CTT100409918, author = {M. Hatakeyama and S. Iwato and K. Nakamura and K. Fujimoto and H. Kawaguchi}, title = {Affinity latex for DNA diagnosis.}, booktitle = {7th Iketani conference, International symposium on advanced technology of fine particles}, year = 1997, } @inproceedings{CTT100528427, author = {岩戸聡子 and 畠山士 and 藤本啓二 and 半田宏 and 川口春馬}, title = {DNA固定ラテックスを用いた点変異検出システムの構築}, booktitle = {高分子ミクロスフェア討論会編集委員会}, year = 1996, } @inproceedings{CTT100528424, author = {畠山士 and 小倉豊 and 澤田潤一 and 後藤正英 and 藤本啓二 and 半田宏 and 川口春馬}, title = {ミクロスフェア表面へのポリペプチド鎖への固定化とアフィニティ活性}, booktitle = {高分子学会}, year = 1996, } @inproceedings{CTT100409920, author = {M. Hatakeyama and Y. Ogura and J. Sawada and M. Goto and K. Fujimoto and H. Handa and H. Kawaguchi}, title = {Preparation of polypeptide-carrying microspheres and their affinity activity.}, booktitle = {36th IUPAC International Symposium on Macromolecules}, year = 1996, } @inproceedings{CTT100528419, author = {畠山士 and 今井剛 and 藤本啓二 and 半田宏 and 川口春馬}, title = {転写タンパク分離精製のためのいくつかのアフィニティラテックス}, booktitle = {日本MRS学会}, year = 1995, } @inproceedings{CTT100528414, author = {畠山士 and 藤本啓二 and 半田宏 and 川口春馬}, title = {ラテックス粒子へのポリペプチドのハイブリッド化}, booktitle = {高分子学会}, year = 1995, } @inproceedings{CTT100409921, author = {M. Hatakeyama and Y. Ogura and J. Sawada and K. Fujimoto and H. Handa and H. Kawaguchi}, title = {Affinity separation by latex particles.}, booktitle = {The Second Far-Eastern Symposium on Biomedical Materials}, year = 1995, } @inproceedings{CTT100528409, author = {畠山士 and 白谷俊史 and 藤本啓二 and 半田宏 and 川口春馬}, title = {転写因子精製のためのアフィニティラテックス}, booktitle = {高分子ミクロスフェア討論会編集委員会}, year = 1994, } @misc{CTT100409915, author = {畠山士 and 加部泰明 and 半田宏}, title = {ナノテクノロジーによる薬物レセプター探索}, year = 2004, } @misc{CTT100409916, author = {加部泰明 and 畠山士 and 半田宏}, title = {新規アフィニティービーズの構築とその応用}, year = 2003, } @misc{CTT100594289, author = {Mamoru Hatakeyama}, title = {高分子ミクロスフェアを用いたアフィニティ分離と遺伝子診断への応用}, year = 1998, } @phdthesis{CTT100594289, author = {Mamoru Hatakeyama}, title = {高分子ミクロスフェアを用いたアフィニティ分離と遺伝子診断への応用}, school = {慶應義塾大学}, year = 1998, }