@book{CTT100848796, author = {木曽良明 and 秋山 泰 and 大上 雅史 and 吉川 寧 and 和久井 直樹}, title = {中分子創薬に適した特性を有する環状ペプチドのインシリコ設計(第8章)}, publisher = {シーエムシー出版}, year = 2019, } @article{CTT100795110, author = {Takashi Tajimi and Naoki Wakui and Keisuke Yanagisawa and Yasushi Yoshikawa and Masahito Ohue and Yutaka Akiyama}, title = {Computational prediction of plasma protein binding of cyclic peptides from small molecule experimental data using sparse modeling techniques}, journal = {BMC Bioinformatics}, year = 2018, } @article{CTT100851475, author = {Daisuke Kami and Tomoya Kitani and Akihiro Nakamura and Naoki Wakui and Rena Mizutani and Masahito Ohue and Fuyuki Kametani and Nobuyoshi Akimitsu and Satoshi Gojo}, title = {The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency}, journal = {PLOS ONE}, year = 2018, } @article{CTT100783049, author = {Wakui, N. and Yoshino, R. and Yasuo, N. and Ohue, M. and Sekijima, M.}, title = {Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: A molecular dynamics simulation approach}, journal = {Journal of Molecular Graphics and Modelling}, year = 2018, } @inproceedings{CTT100851873, author = {Yuta Yamada and Yasushi Yoshikawa and Naoki Wakui and Masahito Ohue and Yutaka Akiyama}, title = {Development of Membrane Permeability Prediction Method for Cyclic Peptids with Machine Learning}, booktitle = {}, year = 2019, } @inproceedings{CTT100823269, author = {黄毅聰 and 吉川寧 and 和久井直樹 and 大上雅史 and 秋山泰.}, title = {拡張サンプリング法による環状ペプチドの膜透過性予測システムの構築}, booktitle = {研究報告バイオ情報学(BIO)}, year = 2019, } @inproceedings{CTT100810731, author = {山田 雄太 and 吉川 寧 and 和久井 直樹 and 大上 雅史 and 秋山 泰}, title = {機械学習を用いた環状ペプチドの膜透過性予測手法の開発}, booktitle = {研究報告バイオ情報学(BIO)}, year = 2019, } @inproceedings{CTT100851460, author = {Takashi Tajimi and Naoki Wakui and Keisuke Yanagisawa and Yasushi Yoshikawa and Masahito Ohue and Yutaka Akiyama}, title = {Computational prediction of plasma protein binding of cyclic peptides from small molecule experimental data using sparse modeling techniques}, booktitle = {BMC Bioinformatics}, year = 2018, } @inproceedings{CTT100776749, author = {多治見隆志 and 和久井直樹 and 大上雅史 and 秋山泰}, title = {複数のLasso回帰解に基づく解釈性の良い予測モデルを目指した環状ペプチド医薬品の体内安定性予測}, booktitle = {研究報告バイオ情報学(BIO)}, year = 2018, } @inproceedings{CTT100783054, author = {Naoki Wakui and Ryunosuke Yoshino and Nobuaki Yasuo and Masahito Ohue and Masakazu Sekijima}, title = {Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: a molecular dynamics simiulation approach}, booktitle = {}, year = 2017, } @inproceedings{CTT100703206, author = {和久井直樹 and 大上雅史 and 千葉峻太朗 and 石田貴士 and 岩﨑博史 and 秋山泰}, title = {既知の活性/非活性化合物のドッキング解析によるバーチャルスクリーニングに適したタンパク質立体構造モデルの選択}, booktitle = {研究報告バイオ情報学(BIO)}, year = 2015, } @misc{CTT100807255, author = {和久井直樹}, title = {分子動力学シミュレーションによるアポトーシス抑制性タンパク質阻害剤の標的選択性に関する研究}, year = 2018, } @misc{CTT100807235, author = {和久井直樹}, title = {分子動力学シミュレーションによるアポトーシス抑制性タンパク質阻害剤の標的選択性に関する研究}, year = 2018, } @misc{CTT100807243, author = {和久井直樹}, title = {分子動力学シミュレーションによるアポトーシス抑制性タンパク質阻害剤の標的選択性に関する研究}, year = 2018, } @phdthesis{CTT100807255, author = {和久井直樹}, title = {分子動力学シミュレーションによるアポトーシス抑制性タンパク質阻害剤の標的選択性に関する研究}, school = {東京工業大学}, year = 2018, } @phdthesis{CTT100807235, author = {和久井直樹}, title = {分子動力学シミュレーションによるアポトーシス抑制性タンパク質阻害剤の標的選択性に関する研究}, school = {東京工業大学}, year = 2018, } @phdthesis{CTT100807243, author = {和久井直樹}, title = {分子動力学シミュレーションによるアポトーシス抑制性タンパク質阻害剤の標的選択性に関する研究}, school = {東京工業大学}, year = 2018, }