@article{CTT100915694,
  author = {Hiyoshi N and Enomoto T and Uefune F and Kato Y and Wu Y and Araki K and Sakano D and Shiraki N and Kume S.},
  title = {A specific plasma amino acid profile in the Insulin2Q104del Kuma mice at the diabetic state and reversal from hyperglycemia.},
  journal = {Biochem. Biophys. Res. Commun.},
  year = 2023,
}

@article{CTT100915687,
  author = {Tokuma H and Sakano D and Shiraki N and Kume S},
  title = {Selective proteasome degradation of the C-terminally-truncated human WFS1 mutants in the pancreatic beta cells.},
  journal = {FEBS Open Bio.},
  year = 2023,
}

@article{CTT100882633,
  author = {Fumiya Uefune and Toru Aonishi and Tetsuya Kitaguchi and Harumi Takahashi and Susumu Seino and Daisuke Sakano and Shoen Kume},
  title = {Dopamine Negatively Regulates Insulin Secretion Through Activation of D1-D2 Receptor Heteromer},
  journal = {Diabetes},
  year = 2022,
}

@article{CTT100863388,
  author = {Yasunobu Asawa and Kei Nishida and Kazuki Kawai and Kiyotaka Domae and Hyun Seung Ban and Akihiro Kitazaki and Hiroya Asami and Jun-Ya Kohno and Satoshi Okada and Hiraku Tokuma and Daisuke Sakano and Shoen Kume and Masaru Tanaka and Hiroyuki Nakamura},
  title = {Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation},
  journal = {Bioconjugate Chemistry},
  year = 2021,
}

@article{CTT100780713,
  author = {Daisuke Sakano and Shoen Kume and Andersson O},
  title = {Inhibition of Cdk5 Promotes β-cell differentiation from ductal progenitors.},
  journal = {Diabetes},
  year = 2018,
}

@article{CTT100724016,
  author = {Daisuke Sakano and Choi S and Kataoka M and Shiraki N and Uesugi M and Kume K and Shoen Kume},
  title = {Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass.},
  journal = {Stem cell reports},
  year = 2016,
}

@article{CTT100712648,
  author = {Omori, H. and Ogaki, S. and Daisuke Sakano and Sato, M. and Umeda, K. and Takeda, N. and Nakagata, N. and Shoen Kume},
  title = {Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development},
  journal = {FEBS Letters},
  year = 2016,
}

@article{CTT100724022,
  author = {Nakashima, R. and Morooka, M. and Shiraki, N. and Daisuke Sakano and Ogaki, S. and Kume, K. and Kume, S.},
  title = {Neural cells play an inhibitory role in pancreatic differentiation of pluripotent stem cells},
  journal = {Genes to Cells},
  year = 2015,
}

@article{CTT100780724,
  author = {Nakashima R and Shiraki N and Daisuke Sakano and Ogaki S and Kume K and Shoen Kume},
  title = {Neural cells play an inhibitory role in pancreatic differentiation of pluripotent stem cells.},
  journal = {Genes to Cells},
  year = 2015,
}

@article{CTT100704221,
  author = {Shahjalal HM and Shiraki N and Daisuke Sakano and Kikawa K and Ogaki S and Baba H and Kume K and Shoen Kume},
  title = {Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system.},
  journal = {Journal of Molecular Cellular and Biology},
  year = 2014,
}

@article{CTT100724018,
  author = {Kazuhide Kikawa and Daisuke Sakano and Nobuaki Shiraki and Tomonori Tsuyama and Kazuhiko Kume and Fumio Endo and Shoen Kume},
  title = {Beneficial Effect of Insulin Treatment on Islet Transplantation Outcomes in Akita Mice},
  journal = {Plos One},
  year = 2014,
}

@article{CTT100724017,
  author = {Shahjalal, H.Md. and Shiraki, N. and Daisuke Sakano and Kikawa, K. and Ogaki, S. and Baba, H. and Kume, K. and Kume, S.},
  title = {Generation of insulin-producing β-like cells from human iPS cells in a defined and completely xeno-free culture system},
  journal = {Journal of Molecular Cell Biology},
  year = 2014,
}

@article{CTT100780621,
  author = {Daisuke Sakano and Shiraki N and Kikawa K and Yamazoe T and Kataoka M and Umeda K and Araki K and Mao D and Matsumoto S and Nakagata N and Andersson O and Stainier D and Endo F and Kume K and Uesugi M and Shoen Kume},
  title = {VMAT2 identified as a regulator of late-stage β-cell differentiation.},
  journal = {Nature Chemical Biology},
  year = 2014,
}

@article{CTT100713329,
  author = {Iwashita, Hidefumi and Nobuaki Shiraki and Daisuke Sakano and Ikegami, Takashi and Shiga, Masanobu and Kazuhiko Kume and Shoen Kume},
  title = {Secreted Cerberus1 as a Marker for Quantification of Definitive Endoderm Differentiation of the Pluripotent Stem Cells},
  journal = {Plos One},
  year = 2013,
}

@article{CTT100704232,
  author = {Kataoka M and Kawamuro Y and Shiraki N and Miki R and Daisuke Sakano and Yoshida T and Yasukawa T and Kume K and Shoen Kume},
  title = {Recovery from diabetes in neonatal mice after a low-dose streptozotocin treatment.},
  journal = {},
  year = 2013,
}

@article{CTT100712655,
  author = {Daisuke Sakano and Shiraki, N. and Kume, S.},
  title = {The view of stem cell therapy for type 1 diabetes},
  journal = {Journal of the Japan Diabetes Society},
  year = 2011,
}

@article{CTT100712656,
  author = {Hossain, M.T. and Teshiba, S. and Shigeoka, Y. and Fujisawa, T. and Inoko, Y. and Daisuke Sakano and Yamamoto, K. and Banno, Y. and Aso, Y.},
  title = {Structural properties of silkworm small heat-shock proteins:SHSP19.9 and sHSP20.8},
  journal = {Bioscience, Biotechnology and Biochemistry},
  year = 2010,
}

@article{CTT100712657,
  author = {Daisuke Sakano and Kato, A. and Parikh, N. and McKnight, K. and Terry, D. and Stefanovic, B. and Kato, Y.},
  title = {BCL6 canalizes Notch-dependent transcription, excluding Mastermind-like1 from selected target genes during left-right patterning.},
  journal = {Developmental cell},
  year = 2010,
}

@article{CTT100712631,
  author = {Sakano Daisuke and Li Bin and Xia Qingyou and YAMAMOTO Kohji and FUJII Hiroshi and ASO Yoichi},
  title = {Genes Encoding Small Heat Shock Proteins of the Silkworm, Bombyx mori},
  journal = {Bioscience, biotechnology, and biochemistry},
  year = 2006,
}

@article{CTT100712659,
  author = {Zhang, P. and Yamamoto, K. and Aso, Y. and Banno, Y. and Daisuke Sakano and Wang, Y. and Fujii, H.},
  title = {Proteomic studies of isoforms of the P25 component of Bombyx mori fibroin},
  journal = {Bioscience, Biotechnology and Biochemistry},
  year = 2005,
}

@article{CTT100712660,
  author = {Daisuke Sakano and Furusawa, T. and Sugimura, Y. and Storey, J.M. and Storey, K.B.},
  title = {Metabolic shifts in carbohydrate metabolism during embryonic development of non-diapause eggs of the silkworm, Bombyx mori},
  journal = {Journal of Insect Biotechnology and Sericology},
  year = 2004,
}

@inproceedings{CTT100916692,
  author = {岸本 恵理子 and 徳間 啓 and 井上 愛里 and 白木 伸明 and 坂野 大介 and 粂 昭苑},
  title = {HSVTK-GCV スイッチを利用した iPS 細胞由来β細胞における造腫瘍抑制},
  booktitle = {},
  year = 2023,
}

@inproceedings{CTT100916690,
  author = {富永成海 and 上船史弥 and 井上愛⾥ and 板⾕勇輝 and 徳間啓 and ⽩⽊伸明 and 坂野⼤介 and 粂昭苑},
  title = {膵臓β細胞における不均⼀なドーパミン合成能の⽣理学的役割の解明},
  booktitle = {},
  year = 2023,
}

@inproceedings{CTT100895368,
  author = {Naoya Hiyoshi and Takayuki Enomoto and Airi Inoue and Yusuke Kato and Daisuke Sakano and Kimi Araki and Nobuaki Shiraki and Shoen Kume},
  title = {Investigation of metabolite profile in plasma from Kuma mice using LC-MS/MS},
  booktitle = {},
  year = 2022,
}

@inproceedings{CTT100878698,
  author = {徳間啓 and 坂野大介 and 粂 昭苑},
  title = {WFS1の発現低下とインスリン分泌の関連性の解明},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100878696,
  author = {上船史弥 and 坂野大介 and 粂 昭苑},
  title = {膵β細胞におけるD1-D2ヘテロ多量体を介したドーパミンによるインスリン分泌抑制機構の解明},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100878697,
  author = {井上愛里 and 下道隆広 and 坂野大介 and 粂 昭苑},
  title = {ドパミンによる膵臓発生機構の解明},
  booktitle = {},
  year = 2021,
}

@inproceedings{CTT100852312,
  author = {芝江柾葵 and 上船史弥 and 坂野大介 and 粂 昭苑},
  title = {マウス膵内分泌細胞のVMAT2による膵島の機能制御},
  booktitle = {},
  year = 2020,
}

@inproceedings{CTT100784188,
  author = {井上愛里 and 坂野大介 and 榎本孝幸 and 中原  舞 and 岡田  誠治 and 荒木喜美 and 粂昭苑},
  title = {Insulin2タンパクへのQ104del変異導入による自然発症１型糖尿病モデルマウスの作製},
  booktitle = {},
  year = 2018,
}

@inproceedings{CTT100784180,
  author = {荒木菜 and 豊田悠暉 and 坂野大介 and 粂昭苑},
  title = {膵β細胞発生におけるモノアミンシグナル伝達経路の解明},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100784181,
  author = {豊田悠暉 and 荒木菜 and 坂野大介 and 粂昭苑},
  title = {モノアミンによる膵β細胞の分化及び成熟化調節機構に関する研究},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100784189,
  author = {Uefune F and Sonoda Y and Sakano D and Aonishi T and Kume S},
  title = {Analysis of Vmat2 mediated regulation in insulin secretion},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100784182,
  author = {坂野大介 and 豊田悠暉 and 荒木菜 and 粂昭苑},
  title = {モノアミンシグナルによる膵β細胞の分化・増殖制御},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100744663,
  author = {Hiraku Tokuma and Zixuan Erinn Sim and Fumiya Uefune and Daisuke Sakano and Nobuaki Shiraki and Shoen Kume},
  title = {Establishment and analysis of hiPSC that visualize the INSULIN producing cells},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100744655,
  author = {D.Sakano and S.Kume},
  title = {Monoamine signals control beta-cell differentiation, maturation and function},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100744666,
  author = {Uefune F and Sonoda Y and Sakano D and Aonishi T and Kume S},
  title = {Role of vesicular monoamine transporter 2 in insulin secretion},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100744670,
  author = {Hiraku Tokuma and Erinn Sim Zixuan and Fumiya Uefune and Daisuke Sakano and Nobuaki Shiraki and Shoen Kume.},
  title = {Generation and Characterization of an INSULIN promoter driven mCherry Reporter Human iPS Cell Lines Using CRISPR/Cas9 system},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100724024,
  author = {Daisuke Sakano and 園田雄輝 and Fumiya Uefune and Shoen Kume},
  title = {Monoamine signals that control differentiation and proliferation of pancreatic beta cells},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100724026,
  author = {坂野大介 and 園田雄輝 and 上船史弥 and 粂昭苑},
  title = {モノアミンシグナルによる膵β細胞の増殖・分化の制御},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100724031,
  author = {坂野大介},
  title = {モノアミンシグナルによる膵β細胞の分化、増殖制御},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100724028,
  author = {Daisuke Sakano and 園田雄輝 and Fumiya Uefune and Shoen Kume},
  title = {Monoamine signaling controls cell proliferation and differentiation state of  pancreatic beta cell},
  booktitle = {},
  year = 2016,
}

@inproceedings{CTT100851723,
  author = {Sakano Daisuke and Choi Sungik and Kataoka Masateru and Shiraki Nobuaki and Uesugi Motonari and Kume Kazuhiko and Kume Shoen and 坂野大介},
  title = {Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass},
  booktitle = {Stem cell reports},
  year = 2016,
}

@inproceedings{CTT100724023,
  author = {坂野大介 and 園田雄輝 and 上船史弥 and 粂昭苑},
  title = {モノアミンを介したシグナルによる膵β細胞の増殖・機能調節},
  booktitle = {},
  year = 2015,
}

@inproceedings{CTT100712677,
  author = {坂野 大介 and 粂昭苑},
  title = {膵β細胞研究の進化と展望(第1回)多能性幹細胞から膵β細胞への分化を制御するシグナル},
  booktitle = {Islet equality},
  year = 2014,
}

@inproceedings{CTT100712674,
  author = {坂野 大介 and 粂昭苑},
  title = {VMAT2と膵β細胞分化},
  booktitle = {内分泌・糖尿病・代謝内科},
  year = 2014,
}

@inproceedings{CTT100712675,
  author = {坂野 大介 and 粂昭苑},
  title = {ES細胞・iPS細胞を用いた発生分化の研究と再生医学への応用 (特集 器官の発生と再生の基礎)},
  booktitle = {生体の科学},
  year = 2014,
}

@inproceedings{CTT100712630,
  author = {坂野 大介 and 白木 伸明 and 粂 昭苑},
  title = {iPS細胞を用いた膵β細胞分化誘導の研究},
  booktitle = {日本内科学会雑誌},
  year = 2009,
}

@inproceedings{CTT100712679,
  author = {坂野 大介},
  title = {受賞課題 家蚕の温度ストレス適応性に関する研究 (平成21年度 財団法人衣笠会「繊維学術賞」報告)},
  booktitle = {繊維研究所研究報告},
  year = 2009,
}

@misc{CTT100895356,
  author = {坂野大介 and 粂 昭苑},
  title = {新しい時代の1型糖尿病治療―再生医療の現状もふまえて},
  year = 2022,
}

@misc{CTT100895358,
  author = {坂野大介 and 粂 昭苑},
  title = {膵臓内分泌細胞の発生と分化における1細胞レベルにおける理解},
  year = 2020,
}

@misc{CTT100712681,
  author = {坂野大介 and 粂昭苑},
  title = {-ヒト多能性幹細胞からの機能的な膵β細胞の作出-},
  year = 2015,
}

@misc{CTT100723365,
  author = {Daisuke Sakano and Nobuaki Shiraki and Shoen Kume},
  title = {Pancreatic differentiation from murine embryonic stem cells},
  year = 2015,
}

@misc{CTT100712673,
  author = {坂野 大介 and 粂昭苑},
  title = {ケミカルバイオロジーを応用した機能的β細胞作製 (特集 糖尿病領域における再生医療の現状と展望)},
  year = 2015,
}

@misc{CTT100712676,
  author = {坂野 大介 and 粂 昭苑},
  title = {膵β細胞・膵島の再生研究 (特集 糖尿病 : 診断・治療Update)},
  year = 2014,
}

@misc{CTT100712036,
  author = {木川 和英 and 坂野大介 and 白木 伸明},
  title = {Akitaマウスに対するインスリン治療が膵島移植の成績に与える効果 (特集 小児内分泌学の進歩2014) -- (糖尿病・糖代謝異常)},
  year = 2013,
}

@misc{CTT100712039,
  author = {坂野大介 and 白木 伸明 and 粂昭苑},
  title = {多能性幹細胞から膵β細胞への分化 (特集 発生・分化・再生と代謝関連臓器)},
  year = 2013,
}

@misc{CTT100712678,
  author = {坂野 大介 and 粂昭苑},
  title = {多能性幹細胞からの膵β細胞分化誘導 (特集 臨床医にもわかる糖尿病基礎研究)},
  year = 2012,
}

@misc{CTT100712041,
  author = {坂野大介 and 白木 伸明 and 粂昭苑},
  title = {１型糖尿病治療の新しい知見  ６．ｉＰＳ細胞による糖尿病医療研究のこれから},
  year = 2011,
}

@misc{CTT100712040,
  author = {坂野大介 and 白木 伸明 and 粂昭苑},
  title = {iPS細胞による糖尿病医療研究のこれから},
  year = 2011,
}

@misc{CTT100815586,
  author = {粂昭苑 and 坂野大介 and 榎本孝幸 and 荒木　喜美　 and 岡田　誠治　},
  title = {糖尿病モデル動物},
  howpublished = {公開特許},
  year = 2019,
  month  = {},
  note   = {特願2018-076855(2018/04/12), 特開2019-180315(2019/10/24)}
}