@book{CTT100720778, author = {Hiroyasu Takemoto and Kanjiro Miyata and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Bioresponsive Polymer-Based Nucleic Acid Carriers}, publisher = {}, year = 2014, } @book{CTT100720815, author = {武元宏泰 and 宮田完二郎}, title = {生体内還元環境とそれに応答する薬剤キャリア設計}, publisher = {}, year = 2013, } @article{CTT100773950, author = {Y. Anraku and H. Kuwahara and Y. Fukusato and A. Mizoguchi and T. Ishii and K. Nitta and Y. Matsumoto and K. Toh and K. Miyata and S. Uchida and K. Nishina and K. Osada and K. Itaka and N. Nishiyama and H. Mizusawa and T. Yamasoba and T. Yokota and K. Kataoka}, title = {Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain}, journal = {Nature Communications}, year = 2017, } @article{CTT100752056, author = {Mitsuru Naito and Ryota Azuma and Hiroyasu Takemoto and Mao Hori and Naoto Yoshinaga and Shigehito Osawa and Rimpei Kamegawa and Hyun Jin Kim and Takehiko Ishii and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori}, title = {Multilayered Polyion Complexes with Dissolvable Silica Layer Covered by Controlling Densities of cRGD-conjugated PEG Chains for Cancer-targeted siRNA Delivery}, journal = {Journal of Biomaterials Science, Polymer Edition}, year = 2017, } @article{CTT100752111, author = {C. Moriya and H. Taniguchi and K. Miyata and N. Nishiyama and K. Kataoka and K. Imai}, title = {Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice}, journal = {Carcinogenesis}, year = 2017, } @article{CTT100720807, author = {Yi Yu and Hyun Jin Kim and Peng Mi and Meng Zheng and Hiroyasu Takemoto and Kazuko Toh and Kim Beob Soo and Kotaro Hayashi and Mitsuru Naito and Yu Matsumoto and Kanjiro Miyata and Kazunori Kataoka}, title = {Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.}, journal = {Journal of Controlled Release}, year = 2016, } @article{CTT100714260, author = {Haruka Nishida and Yoko Matsumoto and Kei Kawana and Christie James and Mitsuru Naito and Kim Beob Soo and Kazuko Toh and Hyun Su Min and Yi Yu and Yu Mastumoto and Hyun Jin Kim and Kanjiro Miyata and Ayumi Taguchi and Kensuke Tomio and Aki Yamashita and Tomoko Inoue and Hiroe Nakamura and Asaha Fujimoto and Masakazu Sato and Mitsuyo Yoshida and Katsuyuki Adachi and Takahide Arimoto and Osamu Wada-Hiraike and Katsutoshi Oda and Takeshi Nagamatsu and Nobuhiro Nishiyama and Kazunori Kataoka and Yutaka Osuga and Tomoyuki Fujii}, title = {Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes}, journal = {Journal of Controlled Release}, year = 2016, } @article{CTT100714258, author = {Hirokuni Uchida and Keiji Itaka and Satoshi Uchida and Takehiko Ishii and Tomoya Suma and Kanjiro Miyata and Makoto Oba and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure}, journal = {Journal of the American Chemical Society}, year = 2016, } @article{CTT100720773, author = {Kotaro Hayashi and Hiroyuki Chaya and Shigeto Fukushima and Sumiyo Watanabe and Hiroyasu Takemoto and Kensuke Osada and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers}, journal = {Macromolecular Rapid Communications}, year = 2016, } @article{CTT100720774, author = {Kotaro Hayashi and Hiroyuki Chaya and Shigeto Fukushima and Sumiyo Watanabe and Hiroyasu Takemoto and Kensuke Osada and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Macromol. Rapid Commun. 6/2016.}, journal = {Macromolecular rapid communications}, year = 2016, } @article{CTT100714351, author = {Masahiro Murakami and Kazutaka Nishina and Chie Watanabe and Kie Yoshida-Tanaka and Wenying Piao and Hiroya Kuwahara and Yuji Horikiri and Kanjiro Miyata and Nobuhiro Nishiyama and Kazunori Kataoka and Masayuki Yoshida and Hidehiro Mizusawa and Takanori Yokota}, title = {Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route}, journal = {Scientific Reports}, year = 2015, } @article{CTT100720777, author = {Hui Gao and Hiroyasu Takemoto and Qixian Chen and Mitsuru Naito and Hirokuni Uchida and Xueying Liu and Kanjiro Miyata and Kazunori Kataoka}, title = {Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity}, journal = {Chemical Communications}, year = 2015, } @article{CTT100720776, author = {Meng Zheng and Hyun Jin Kim and Hiroyasu Takemoto and Kanjiro Miyata and Kazunori Kataoka}, title = {Precisely regulated nanoarchitecture comprised of gold nanotemplate and unimer polyion complex for systemic delivery of siRNA}, journal = {Journal of Controlled Release}, year = 2015, } @article{CTT100723941, author = {Yoshinori Maeda and Frederico Pittella and Takahiro Nomoto and Hiroyasu Takemoto and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles}, journal = {Macromolecular Rapid Communications}, year = 2014, } @article{CTT100720785, author = {Frederico Pittella and Cabral Horacio and Yoshinori Maeda and Peng Mi and Sumiyo Watanabe and Hiroyasu Takemoto and Hyun Jin Kim and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles}, journal = {Journal of Controlled Release}, year = 2014, } @article{CTT100720784, author = {Hyun Jin Kim and Hiroyasu Takemoto and Yi Yu and Meng Zheng and Yoshinori Maeda and Hiroyuki Chaya and Kotaro Hayashi and Peng Mi and Frederico Pittella and Christie James and Kazuko Toh and Yu Mastumoto and Nobuhiro Nishiyama and Kanjiro Miyata and Kazunori Kataoka}, title = {Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles}, journal = {Acs Nano}, year = 2014, } @article{CTT100720786, author = {Hiroyasu Takemoto and Kanjiro Miyata and Shota Hattori and Takehiko Ishii and Tomoya Suma and Satoshi Uchida and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Acidic pH-Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosomal Escape with Reduced IFN alpha-Associated Immune Response}, journal = {Angewandte Chemie-International Edition}, year = 2013, } @article{CTT100720789, author = {Kanjiro Miyata and Christie James and Tomoya Suma and Hiroyasu Takemoto and Hirokuni Uchida and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Fine-Tuning of Repeating Aminoethyelene Units in Poly(aspartamide) Side Chains for Enhanced siRNA Delivery}, journal = {Tailored Polymer Architectures For Pharmaceutical and Biomedical Applications}, year = 2013, } @article{CTT100720791, author = {Tomoya Suma and Kanjiro Miyata and Yasutaka Anraku and Sumiyo Watanabe and Christie James and Hiroyasu Takemoto and Momoko Shioyama and Noha Gouda and Takehiko Ishii and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Smart Multilayered Assembly for Biocompatible siRNA Delivery Featuring Dissolvable Silica, Endosome-Disrupting Polycation, and Detachable PEG}, journal = {Acs Nano}, year = 2012, } @article{CTT100720793, author = {Hiroyasu Takemoto and Kanjiro Miyata and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {siRNA-grafted polymer for efficient siRNA delivery system}, journal = {Abstracts of Papers of the American Chemical Society}, year = 2012, } @article{CTT100720790, author = {Hiroyasu Takemoto and Kanjiro Miyata and Takehiko Ishii and Shota Hattori and Shigehito Osawa and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Accelerated Polymer-Polymer Click Conjugation by Freeze-Thaw Treatment}, journal = {Bioconjugate Chemistry}, year = 2012, } @article{CTT100720799, author = {Hiroyasu Takemoto and Atsushi Ishii and Kanjiro Miyata and Masataka Nakanishi and Makoto Oba and Takehiko Ishii and Yuichi Yamasaki and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system}, journal = {Biomaterials}, year = 2010, } @article{CTT100720798, author = {Kanjiro Miyata and Noha Gouda and Hiroyasu Takemoto and Makoto Oba and Yan Lee and Hiroyuki Koyama and Yuichi Yamasaki and Keiji Itaka and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Enhanced transfection with silica-coated polyplexes loading plasmid DNA}, journal = {Biomaterials}, year = 2010, } @article{CTT100720796, author = {Kanjiro Miyata and Takahiro Nomoto and Hiroyasu Takemoto and Hyun Jin Kim and Yu Matsumoto and Makoto Oba and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Development of advanced polymer-based nanodevices for nucleic acids delivery}, journal = {Abstracts of Papers of the American Chemical Society}, year = 2010, } @inproceedings{CTT100774002, author = {Hiroyasu Takemoto and Kanjiro Miyata and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Size-regulated siRNA carriers from small complex loading single siRNA molecule for systemic delivery to tumor tissue}, booktitle = {}, year = 2018, } @inproceedings{CTT100752154, author = {武元宏泰 and キム ヒュンジン and 宮田完二郎 and 西山伸宏 and 片岡一則}, title = {単分子siRNA内包型小会合体を要素とするsiRNAキャリアの構築と全身投与による腫瘍組織への送達}, booktitle = {}, year = 2017, } @inproceedings{CTT100752143, author = {越後真梨那 and 武元 宏泰 and 林 光太朗 and 宮田 完二郎 and 金澤秀子 and 片岡 一則 and 西山 伸宏}, title = {がん細胞内にて特異的に切断される Linker を利用した siRNA 送達キャリアの開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100752141, author = {武元宏泰 and 宮田完二郎 and 林光太朗 and 持田祐希 and 片岡一則 and 西山伸宏}, title = {シロキサンネットワークにて形成されるsiRNA内包有機-無機ハイブリッドナノ粒子の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100768256, author = {Takahiro Nomoto and Shigeto Fukushima and Michiaki Kumagai and Kaori Machitani and Kanjiro Miyata and Makoto Oba and Yu Matsumoto and Kensuke Osada and Nobuhiro Nishiyama and Kazunori Kataoka}, title = {Three-layered polyplex micelle for light-induced gene transfer}, booktitle = {}, year = 2015, }