@book{CTT100720954, author = {Tadashi Eguchi}, title = {大学院講義有機化学 II. 有機合成化学・生物有機化学 第2版 野依良治, 中筋一弘, 玉尾皓平, 奈良坂紘一, 柴崎正勝, 橋本俊一, 鈴木啓介, 山本陽介, 村田道雄編}, publisher = {東京化学同人}, year = 2015, } @book{CTT100542401, author = {江口正(共著)日本化学会 and 編}, title = {化学実験セーフティーガイド}, publisher = {化学同人}, year = 2006, } @book{CTT100468839, author = {K. Kakinuma and T. Eguchi}, title = {D-Glucose: Extremely versatile Resource for Organic Synthesis}, publisher = {My Favorite Organic Synthesis, The Society of Synthetic Organic Chemistry, Japan}, year = 2002, } @book{CTT100422606, author = {O. DANNENMULLER and K. ARAKAWA and T. EGUCHI and K. KAKINUMA and S. BLANC and A.-M. ALBRECHT and M. SCHMUTZ and Y. NAKATANI and G. OURISSON}, title = {Membrane Properties of Archaeal Phospholipids: Effect of Macrocyclization}, publisher = {Giant Vesicles}, year = 1999, } @book{CTT100434140, author = {TADASHI EGUCHI}, title = {創薬化学の基礎となる先導物質の合成法(共著)}, publisher = {廣川書店}, year = 1996, } @article{CTT100895298, author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Cross-Linking of the Nonribosomal Peptide Synthetase Adenylation Domain with a Carrier Protein Using a Pantetheine-Type Probe}, journal = {Non-Ribosomal Peptide Biosynthesis and Engineering: Methods and Protocols}, year = 2023, } @article{CTT100895291, author = {Taichi Chisuga and Satoshi Murakami and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase}, journal = {ACS Chem. Biol.}, year = 2023, } @article{CTT100895296, author = {Fumitaka Kudo and Takuji Chikuma and Mizuki Nambu and Taichi Chisuga and Shimpei Sumimoto and Arihiro Iwasaki and Kiyotake Suenaga and Akimasa Miyanaga and Tadashi Eguchi}, title = {Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii}, journal = {ACS Chem. Biol.}, year = 2023, } @article{CTT100887107, author = {Fumitaka Kudo and Kosuke Kishikawa and Kazuma Tsuboi and Takafusa Kido and Takeo Usui and Junko Hashimoto and Kazuo Shin-ya and Akimasa Miyanaga and Tadashi Eguchi}, title = {Acyltransferase Domain Exchanges between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics}, journal = {ChemBioChem}, year = 2023, } @article{CTT100884597, author = {Akimasa Miyanaga and Koichi Kawada and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi}, title = {Structural Basis of Transient Interactions of the Acyltransferase VinK with the Loading Acyl Carrier Protein of the Vicenistatin Modular Polyketide Synthase}, journal = {BIOCHEMISTRY}, year = 2023, } @article{CTT100882107, author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Recent Advances in Structural Analysis of Adenylation Domain in Natural Product Biosynthesis}, journal = {Curr. Opin. Chem. Biol.}, year = 2022, } @article{CTT100884397, author = {Fumitaka Kudo and Atsushi Minato and Shusuke Sato and Nayuta Nagano and Chitose Maruyama and Yoshimitsu Hamano and Junko Hashimoto and Ikuko Kozone and Kazuo Shin-ya and Tadashi Eguchi}, title = {Mechanism of S-Adenosyl-L-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-L-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis}, journal = {ORG LETT}, year = 2022, } @article{CTT100881283, author = {Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthesis of Cyclitols}, journal = {Nat. Prod. Rep}, year = 2022, } @article{CTT100880056, author = {Taichi Chisuga and Akimasa Miyanaga and Tadashi Eguchi}, title = {Protein–protein Recognition Involved in Intermodular Transacylation Reaction in Modular Polyketide Synthase in the Biosynthesis of Vicenistatin}, journal = {ChemBioChem}, year = 2022, } @article{CTT100869840, author = {Shusuke Sato and Fumitaka Kudo and Tadashi Eguchi}, title = {Characterization of the Cobalamin-Dependent Radical SAM C-Methyltransferase Fom3 in Fosfomycin Biosynthesis}, journal = {Methods Enymol.}, year = 2022, } @article{CTT100866242, author = {Makoto Takashima and Kiyoshi Suzuki and Hideo Mochizuki and Satoshi Uemura and Jin-ichi Inokuchi and Tadashi Eguchi}, title = {Expression of Highly Active Chondroitin 4-O-Sulfotransferase-1 in Escherichia coli by a Trigger Factor Fusion Protein Expression System}, journal = {Process Biochem}, year = 2022, } @article{CTT100865326, author = {Taichi Chisuga and Akira Nagai and Akimasa Miyanaga and Ena Goto and Kosuke Kishikawa and Fumitaka Kudo and Tadashi Eguchi}, title = {Structural Insight into the Reaction Mechanism of Ketosynthase-Like Decarboxylase in a Loading Module of Modular Polyketide Synthases}, journal = {ACS Chem. Biol.}, year = 2022, } @article{CTT100864715, author = {Makoto Takashima and Ippei Watanabe and Akimasa Miyanaga and Tadashi Eguchi}, title = {Substrate Specificity of Chondroitinase ABC I Based on Analyses of Biochemical Reactions and Crystal Structures in Complex with Disaccharides}, journal = {Glycobiology}, year = 2021, } @article{CTT100861310, author = {Akimasa Miyanaga and Risako Ouchi and Fumitaka Kudo and Tadashi Eguchi}, title = {Complex Structure of the Acyltransferase VinK and the Carrier Protein VinL with a Pantetheine Cross-linking Probe}, journal = {Acta Crystallogr F Struct. Biol. Commun.}, year = 2021, } @article{CTT100861907, author = {Shusuke Sato and Fumitaka Kudo and Michel Rohmer and Tadashi Eguchi}, title = {Biochemical and Mutational Analysis of Radical SAM Adenosylhopane Synthase HpnH Derived from Zymomonas mobilis Reveals that the Conserved Cysteine-106 Residue Reduces a Radical Intermediate and Determines the Stereochemistry}, journal = {Biochemistry}, year = 2021, } @article{CTT100847581, author = {Fumitaka Kudo and Yukinobu Kitayama and Akimasa Miyanaga and Mario Numakura and Tadashi Eguchi}, title = {Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis}, journal = {ChemBioChem}, year = 2021, } @article{CTT100845120, author = {Fumitaka Kudo and Sotaro Takahashi and Akimasa Miyanaga and Yuichiro Nakazawa and Kota Nishino and Yuki Hayakawa and Koichi Kawamura and Fumihiro Ishikawa and Naeko Iwai and Yoko Nagumo and Takeo Usui and Tadashi Eguchi}, title = {Mutational Biosynthesis of the Hitachimycin Analogs Regulated by β-Phenylalanine Selective Adenylation Enzyme HitB}, journal = {ACS Chemical Biology}, year = 2021, } @article{CTT100842144, author = {Fumitaka Kudo and Ayaka Mori and Mai Koide and Ryo Yajima and Ryohei Takeishi and Akimasa Miyanaga and Tadashi Eguchi}, title = {One-pot Enzymatic Synthesis of 2-Deoxy-scyllo-inosose from D-Glucose and Polyphosphate}, journal = {Biosci. Biotechnol. Biochem.}, year = 2021, } @article{CTT100840666, author = {Tadashi Eguchi}, title = {巻頭言:新しい時代の研究スタイルとは}, journal = {有機合成化学協会誌}, year = 2020, } @article{CTT100833477, author = {Akimasa Miyanaga and Ryoma Takaku and Makoto Takaishi and Etsu Tashiro and Fumitaka Kudo and Tadashi Eguchi}, title = {Generation of Incednine Derivatives by Mutasynthesis}, journal = {J. Antibiot.}, year = 2020, } @article{CTT100829288, author = {Akimasa Miyanaga and Shohei Kurihara and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi}, title = {Structural Characterization of Complex of Adenylation Domain and Carrier Protein by using Pantetheine Cross-linking Probe}, journal = {ACS Chem. Biol.}, year = 2020, } @article{CTT100823503, author = {Chitose Maruyama and Yukiko Chinone and Shusuke Sato and Fumitaka Kudo and Kosuke Ohsawa and Junya Kubota and Junko Hashimoto and Ikuko Kozone and Takayuki Doi and Kazuo Shin-ya and Tadashi Eguchi and Yoshimitsu Hamano}, title = {C-Methylation of S-Adenosyl-L-methionine Occurs prior to Cyclopropanation in the Biosynthesis of a Bacterial 1-Amino-2-methylcyclopropanecarboxylic Acid (Norcoronamic acid) in a Bacterium}, journal = {Biomolecules}, year = 2020, } @article{CTT100821998, author = {Fumitaka Kudo and Yukinobu Kitayama and Akimasa Miyanaga and Akane Hirayama and Tadashi Eguchi}, title = {Biochemical and Structural Analysis of a Dehydrogenase KanD2 and an Aminotransferase KanS2 that are Responsible for the Construction of the Kanosamine Moiety in Kanamycin Biosynthesis}, journal = {Biochemistry}, year = 2020, } @article{CTT100820078, author = {Fumitaka Kudo and Tadashi Eguchi}, title = {生体内におけるラジカル反応:ラジカル酵素による炭素–炭素結合形成反応}, journal = {化学}, year = 2020, } @article{CTT100811958, author = {Shusuke Sato and Fumitaka Kudo and Michel Rohmer and Tadashi Eguchi}, title = {Characterization of Radical SAM Adenosylhopane Synthase, HpnH, which Catalyzes the 5’-Deoxyadenosyl Radical Addition to Diploptene in the Biosynthesis of C35 Bacteriohopanepolyols}, journal = {Angew. Chem. Int. Ed.}, year = 2020, } @article{CTT100809797, author = {Daisuke Kawasaki and Akimasa Miyanaga and Taichi Chisuga and Fumitaka Kudo and Tadashi Eguchi}, title = {Functional and Structural Analyses of Split-Dehydratase Domain in the Biosynthesis of Macrolactam Polyketide Cremimycin}, journal = {Biochemistry}, year = 2019, } @article{CTT100813105, author = {Fumitaka Kudo and Takeshi Tsunoda and Kaito Yamaguchi and Akimasa Miyanaga and Tadashi Eguchi}, title = {Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis}, journal = {Biochemistry}, year = 2019, } @article{CTT100804280, author = {Shusuke Satou and Fumitaka Kudo and Tadashi Eguchi}, title = {抗生物質ホスホマイシン生合成の全貌解明}, journal = {バイオサイエンスとインダストリー}, year = 2019, } @article{CTT100806649, author = {Fumitaka Kudo and Jiahao Zhang and Shusuke Sato and Akane Hirayama and Tadashi Eguchi}, title = {Functional Characterization of 3-Aminobenzoic Acid Adenylation Enzyme PctU and UDP-N-Acetyl-D-Glucosamine: 3-Aminobenzoyl-ACP Glycosyltransferase PctL in Pactamycin Biosynthesis}, journal = {ChemBioChem}, year = 2019, } @article{CTT100799606, author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Structural Analysis of Glycine Oxidase Homologue CmiS2 Reveals a Unique Substrate Recognition Mechanism for Formation of a β-Amino Acid Starter Unit in Cremimycin Biosynthesis}, journal = {BIOCHEMISTRY}, year = 2019, } @article{CTT100798092, author = {Xiaoli Zhang and Wei Chen and Qiong Gao and Junsheng Yang and Xueni Yan and Han Zhao and Lin Su and Meimei Yang and Chenlang Gao and Yao Yao and Ken Inoki and Dan Li and Rong Shao and Shiyi Wang and Nirakar Sahoo and Fumitaka Kudo and Tadashi Eguchi and Benfang Ruan and Haoxing Xu}, title = {Rapamycin Directly Activates Lysosomal Mucolipin TRP Channels Independent of mTOR}, journal = {PLOS Biol.}, year = 2019, } @article{CTT100795800, author = {Fumihiro Ishikawa and Akimasa Miyanaga and Hinano Kitayama and Shinya Nakamura and Isao Nakanishi and Fumitaka Kudo and Tadashi Eguchi and Genzoh Tanabe}, title = {An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket}, journal = {Angew. Chem. Int. Ed.}, year = 2019, } @article{CTT100793478, author = {Jolanta Cieślak and Akimasa Miyanaga and Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi}, title = {Functional and Structural Characterization of Adenylation Enzyme IdnL7 Involved in Incednine Biosynthesis}, journal = {Acta Crystallogr. F Struct. Biol. Commun.}, year = 2019, } @article{CTT100790301, author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi}, title = {Structural Basis of Nonribosomal Codes for Nonproteinogenic Amino Acid Selective Adenylation Enzymes in the Biosynthesis of Natural Products}, journal = {J. Ind. Microbiol. Biotechnol.}, year = 2019, } @article{CTT100777252, author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Protein-Protein Interactions in Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Assembly Lines}, journal = {Nat. Prod. Rep.}, year = 2018, } @article{CTT100770362, author = {Shusuke Sato and Fumitaka Kudo and Tomohisa Kuzuyama and Friedrich Hammerschmidt and Tadashi Eguchi}, title = {C-Methylation Catalyzed by Fom3, a Cobalamin-Dependent Radical S-Adenosyl-L-methionine Enzyme in Fosfomycin Biosynthesis, Proceeds with Inversion of Configuration}, journal = {BIOCHEMISTRY}, year = 2018, } @article{CTT100770338, author = {Shusuke Sato and Akimasa Miyanaga and Seung-Young Kim and Tomohisa Kuzuyama and Fumitaka Kudo and Tadashi Eguchi}, title = {Biochemical and Structural Analysis of FomD that Catalyzes the Hydrolysis of Cytidylyl (S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis}, journal = {BIOCHEMISTRY}, year = 2018, } @article{CTT100769097, author = {Akimasa Miyanaga and Risako Ouchi and Fumihiro Ishikawa and Ena Goto and Genzoh Tanabe and Fumitaka Kudo and Tadashi Eguchi}, title = {Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis}, journal = {J. Am. Chem. Soc.}, year = 2018, } @article{CTT100758522, author = {Akane Hirayama and Jinmiao Chu and Ena Goto and Fumitaka Kudo and Tadashi Eguchi}, title = {NAD(+)-Dependent Dehydrogenase PctP and PLP-Dependent Aminotransferase PctC Catalyze the First Post-glycosylation Modification of Sugar Intermediate in Pactamycin Biosynthesis}, journal = {ChemBioChem}, year = 2018, } @article{CTT100758696, author = {Satoru Watanabe and Hiroaki Ozawa and Hiroaki Kato and Kaori Nimura-Matsune and Toshifumi Hirayama and Fumitaka Kudo and Tadashi Eguchi and Katsumi Kakinuma and Hirofumi Yoshikawa}, title = {Carbon-free Production of 2-Deoxy-scyllo-inosose (DOI) in Cyanobacterium Synechococcus elongatus PCC 7942}, journal = {Biosci. Biotechnol. Biochem.}, year = 2018, } @article{CTT100755156, author = {Akimasa Miyanaga and Ryuichi Takayanagi and Takashi Furuya and Ayano Kawamata and Tomohiro Itagaki and Yoshiharu Iwabuchi and Naoki Kanoh and Fumitaka Kudo and Tadashi Eguchi}, title = {Substrate Recognition by a Dual-Function P450 Monooxygenase Involved in FD-891 Biosynthesis}, journal = {ChemBioChem}, year = 2017, } @article{CTT100749760, author = {Su-Hee Cho and Seung-Young Kim and Takeo Tomita and Taro Shiraishi and Jin-Soo Park and Shusuke Sato and Fumitaka Kudo and Tadashi Eguchi and Nobutaka Funa and Makoto Nishiyama and Tomohisa Kuzuyama}, title = {Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme}, journal = {ACS Chem. Biol.}, year = 2017, } @article{CTT100744572, author = {Cieślak J and Miyanaga A and Takaku R and Takaishi M and Amagai K and Kudo F and Eguchi T}, title = {Biochemical characterization and structural insight into aliphatic β-amino acid adenylation enzymes IdnL1 and CmiS6}, journal = {Proteins: Structure, Function, and Bioinformatics}, year = 2017, } @article{CTT100744573, author = {Chisuga T and Miyanaga A and Kudo F and Eguchi T}, title = {Structural analysis of the dual function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an α,β-unsaturated thioester}, journal = {J Biol Chem}, year = 2017, } @article{CTT100747989, author = {Shusuke Sato and Fumitaka Kudo and Seung-Young Kim and Tomohisa Kuzuyama and Tadashi Eguchi}, title = {Methylcobalamin-Dependent Radical SAM C-Methyltransferase Fom3 Recognizes Cytidylyl-2-hydroxyethylphosphonate and Catalyzes the Nonstereoselective C-Methylation in Fosfomycin Biosynthesis}, journal = {Biochemistry}, year = 2017, } @article{CTT100744357, author = {Keita Amagai and Haruo Ikeda and Junko Hashimoto and Ikuko Kozone and Miho Izumikawa and Fumitaka Kudo and Tadashi Eguchi and Takemichi Nakamura and Hiroyuki Osada and Shunji Takahashi and Kazuo Shin-ya}, title = {Identification of a Gene Cluster for Telomestatin Biosynthesis and Heterologous Expression Using a Specific Promotor in a Clean Host}, journal = {Sci. Rep.}, year = 2017, } @article{CTT100737484, author = {Fumitaka Kudo and Takahiro Tokumitsu and Tadashi Eguchi}, title = {Substrate Specificity of Radical S-Adenosyl-L-methionine Dehydratase AprD4 and Its Partner Reductase AprD3 in the C3′-Deoxygenation of Aminoglycoside Antibiotics}, journal = {J. Antibiot.}, year = 2017, } @article{CTT100714562, author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Mechanisms of β-Amino Acid Incorporation in Polyketide Macrolactam Biosynthesis}, journal = {Curr. Opin. Chem. Biol.}, year = 2016, } @article{CTT100734359, author = {Fumitaka Kudo and Takeshi Tsunoda and Makoto Takashima and Tadashi Eguchi}, title = {Five-membered Cyclitol Phosphate Formation by a myo-Inositol Phosphate Synthase Ortholog in the Biosynthesis of the Carbocyclic Nucleoside Antibiotic Aristeromycin}, journal = {ChemBioChem}, year = 2016, } @article{CTT100714590, author = {Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {天然物生合成酵素によるキャリアータンパク質の認識機構}, journal = {バイオサイエンスとインダストリー}, year = 2016, } @article{CTT100711106, author = {Fumitaka Kudo and Yasunori Matsuura and Takaaki Hayashi and Masayuki Fukushima and Tadashi Eguchi}, title = {Genome Mining of the Sordarin Biosynthetic Gene Cluster from Sordaria araneosa Cain ATCC 36386: Characterization of Cycloaraneosene Synthase and GDP-6-Deoxyaltrose Transferase}, journal = {J. Antibiot.}, year = 2016, } @article{CTT100704202, author = {Yuko Nishiyama and Tomohiro Ohmichi and Sayaka Kazami and Hiroki Iwasaki and Kousuke Mano and Yoko Nagumo and Fumitaka Kudo and Sosaku Ichikawa and Yoshiharu Iwabuchi and Naoki Kanoh and Tadashi Eguchi and Hiroyuki Osada and Takeo Usui}, title = {Vicenistatin Induces the Early Endosome-derived Vacuole Formation in Mammalian Cells}, journal = {Biosci. Biotechnol. Biochem.}, year = 2016, } @article{CTT100704203, author = {Akimasa Miyanaga and Yuki Hayakawa and Mario Numakura and Junko Hashimoto and Kuniko Teruya and Takashi Hirano and Kazuo Shin-ya and Fumitaka Kudo and Tadashi Eguchi}, title = {Identification of the Fluvirucin B2 (Sch 38518) Biosynthetic Gene Cluster from Actinomadula fulva subsp. indica ATCC 53714: Substrate Specificity of β-amino Acid Selective Adenylating Enzyme FlvN}, journal = {Biosci. Biotechnol. Biochem.}, year = 2016, } @article{CTT100704213, author = {Naoki Kanoh and Tomohiro Itagaki and Ayano Kawamata and Miho Takeuchi and Keisuke Hamada and Yoshiharu Iwabuchi and Tadashi Eguchi and Fumitaka Kudo and Takeo Usui}, title = {Synthesis and Structure-activity Relationship Study of FD891: Importance of the Side Chain and C8-C9 Epoxide for Cytotoxic Activity against Cancer Cells}, journal = {J. Antibiot.}, year = 2016, } @article{CTT100701945, author = {Fumitaka Kudo and Tadashi Eguchi}, title = {Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinary of Old Drugs}, journal = {Chem. Rec.}, year = 2016, } @article{CTT100701323, author = {Akimasa Miyanaga and Shohei Iwasawa and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi}, title = {Structure-based Analysis of the Molecular Interactions between Acyltransferase and Acyl Carrier Protein in Vicenistatin Biosynthesis}, journal = {Proc. Natl. Acad. Sci. USA}, year = 2016, } @article{CTT100701015, author = {Fumitaka Kudo and Koichi Kawamura and Takashi Furuya and Hiroto Yamanishi and Atsushi Motegi and Akiko Komatsubara and Mario Numakura and Akimasa Miyanaga and Tadashi Eguchi}, title = {Parallel Post-Polyketide Synthase Modification Mechanism Involved in FD-891 Biosynthesis in Streptomyces graminofaciens A-8890}, journal = {ChemBioChem}, year = 2016, } @article{CTT100698953, author = {Akane Hirayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Mechanism-based Trapping of the Quinonoid Intermediate Using the K276R Mutant of PLP-Dependent 3-Aminobenzoate Synthase PctV in the Biosynthesis of Pactamycin}, journal = {ChemBioChem}, year = 2015, } @article{CTT100724227, author = {Y. Yamada and S. Arima and T. Nagamitsu and Johmoto Kohei and H. Uekusa and TADASHI EGUCHI and K. Shin-ya and D. E. Cane and H. Ikeda}, title = {Novel terpenes generated by heterologous expression of bacterial terpene synthase genes in an engineered Streptomyces host}, journal = {J. Antibiot.}, year = 2015, } @article{CTT100691925, author = {Yuuki Yamada and Shiho Arima and Tohru Nagamitsu and Kohei Johmoto and Hidehiro Uekusa and Tadashi Eguchi and Kazuo Shin-ya and David E. Cane and Haruo Ikeda}, title = {Novel Terpenes Generated by Heterologous Expression of Bacterial Terpene Synthase Genes in an Engineered Streptomyces Host}, journal = {J. Antibiot.}, year = 2015, } @article{CTT100685171, author = {Fumitaka Kudo and Koichi Kawamura and Asuka Uchino and Akimasa Miyanaga and Mario Numakura and Ryuichi Takayanagi and Tadashi Eguchi}, title = {Genome Mining of Hitachimycin Biosynthetic Gene Cluster; Involvement of Phenylalanine-2,3-aminomutase in the Biosynthesis}, journal = {ChemBioChem}, year = 2015, } @article{CTT100682076, author = {Ryohei Takeishi and Fumitaka Kudo and Mario Numakura and Tadashi Eguchi}, title = {Epimerization at C-3’’ in Butirosin Biosynthesis by an NAD(+)-Dependent Dehydrogenase BtrE and an NADPH-Dependent Reductase BtrF}, journal = {ChemBioChem}, year = 2015, } @article{CTT100677894, author = {Akimasa Miyanaga and Jolanta Cieślak and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi}, title = {The Crystal Structure of Adenylation Enzyme VinN Reveals a Unique β-Amino Acid Recognition Mechanism}, journal = {J. Biol. Chem.}, year = 2014, } @article{CTT100676692, author = {Fumitaka Kudo and Shota Hoshi and Taiki Kawashima and Toshiaki Kamachi and Tadashi Eguchi}, title = {Characterization of a Radical S‑Adenosyl‑L‑methionine Epimerase, NeoN, in the Last Step of Neomycin B Biosynthesis}, journal = {J. Am. Chem. Soc.}, year = 2014, } @article{CTT100675647, author = {TADASHI EGUCHI}, title = {微生物二次代謝産物生合成の精密解析}, journal = {The Japanese Journal of Antibiotics}, year = 2014, } @article{CTT100674034, author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi}, title = {Biosynthesis of Natural Products Containing β-Amino Acids}, journal = {Nat. Prod. Rep.}, year = 2014, } @article{CTT100667944, author = {Yuji Shinohara and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {The Crystal Structure of the Amidohydrolase VinJ Shows a Unique Hydrophobic Tunnel for its Interaction with Polyketide Substrates}, journal = {FEBS Lett}, year = 2014, } @article{CTT100665526, author = {Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi}, title = {Identification of Incednine Biosynthetic Gene Cluster: Characterization of Novel β-Glutamate-β-decarboxylase IdnL3}, journal = {J. Antibiot.}, year = 2013, } @article{CTT100664822, author = {Mai Koide and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Characterization of Polyphosphate Glucokinase SCO5059 from Streptomyces coelicolor A3(2)}, journal = {Biosci. Biotechnol. Biochem}, year = 2013, } @article{CTT100660856, author = {Keita Amagai and Ryoma Takaku and Fumitaka Kudo and Tadashi Eguchi}, title = {A Unique Amino Transfer Mechanism for Constructing the β-Amino Fatty Acid Starter Unit in the Biosynthesis of Macrolactam Antibiotic Cremimycin}, journal = {ChemBioChem}, year = 2013, } @article{CTT100658213, author = {Akane Hirayama and Tadashi Eguchi and Fumitaka Kudo}, title = {A Single PLP-Dependent Enzyme PctV Catalyzes the Transformation of 3-Dehydroshikimate into 3-Aminobenzoate in the Biosynthesis of Pactamycin}, journal = {ChemBioChem}, year = 2013, } @article{CTT100658609, author = {Shiori Itagaki and Minami Haga and Yuji Oikawa and Ayaka Sakoda and Yoshie Ohke and Hiroshi Sawada and Tadashi Eguchi and Hideyuki Tamegai}, title = {Difference on the Roles of of Glutamine Amidotransferase Subunit of Pyridoxal 5'-Phosphate Synthase between Bacillus circulans and Bacillus subtilis}, journal = {Biosci. Biotechnol. Biochem.}, year = 2013, } @article{CTT100646029, author = {Hayato Fukuda and Yuko Nishiyama and Shiina Nakamura and Yutaro Ohno and Tadashi Eguchi and Yoshiharu Iwabuchi and Takeo Usui and Naoki Kanoh}, title = {Synthesis and Structure-Activity Relationship of Vicenistatin, a Cytotoxic 20-Membered Macrolactam Glycoside}, journal = {Chem. Asian J}, year = 2012, } @article{CTT100642612, author = {Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi}, title = {A Unique Pathway for the 3-Aminobutyrate Starter Unit from L-Glutamate through β-Glutamate during Biosynthesis of the 24-Membered Macrolactam Antibiotic, Incednine}, journal = {Org. Lett.}, year = 2012, } @article{CTT100640083, author = {Fumitaka Kudo and Yusaku Asou and Moe Watanabe and Takashi Kitayama and Tadashi Eguchi}, title = {Potent Oligomerization and Macrocyclization Activity of the Thioesterase Domain of Vicenistatin Polyketide Synthase}, journal = {Synlett}, year = 2012, } @article{CTT100634881, author = {Hilda Sucipto and Fumitaka Kudo and Tadashi Eguchi}, title = {The Last Step of Kanamycin Biosynthesis: Unique Deamination Reaction Catalyzed by the α-Ketoglutarate-dependent Nonheme Iron Dioxygenase KanJ and the NADPH Dependent Reductase KanK}, journal = {Angew. Chem. Int. Ed.}, year = 2012, } @article{CTT100631778, author = {Eriko Nango and Takashi Yamamoto and Takashi Kumasaka and Tadashi Eguchi}, title = {Structure of Thermus thermophilus Homoisocitrate Dehydrogenase in Complex with a Designed Inhibitor}, journal = {J. Biochem.}, year = 2011, } @article{CTT100630082, author = {Keita Amagai and Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthetic Pathway of Macrolactam Polyketide Antibiotic Cremimycin}, journal = {Tetrahedron}, year = 2011, } @article{CTT100631073, author = {Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi}, title = {A Natural Protecting Group Strategy To Carry an Amino Acid Starter Unit in the Biosynthesis of Macrolactam Polyketide Antibiotics}, journal = {J. Am. Chem. Soc.}, year = 2011, } @article{CTT100630342, author = {Chiaki Nakano and Fumitaka Kudo and Tadashi Eguchi and Yasuo Ohnishi}, title = {Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (-)-epi-α-Bisabolol and (-)-Germacradiene-4-ol Synthases from Streptomyces citricolor}, journal = {ChemBioChem}, year = 2011, } @article{CTT100616607, author = {Takeshi Hoshino and Eriko Nango and Seiki Baba and Tadashi Eguchi and Takashi Kumasaka}, title = {Crystallization and Preliminary X-ray Analysis of Isopentenyl Diphosphate Isomerase from Methanocaldococcus jannaschii}, journal = {Acta Cryst.}, year = 2011, } @article{CTT100617878, author = {Fumitaka Kudo and Takanori Yonezawa and Akiko Komatsubara and Kazutoshi Mizoue and Tadashi Eguchi}, title = {Cloning of the Biosynthetic Gene Cluster for Naphtoxanthene Antibiotic FD-594 from Streptomyces sp. TA-0256}, journal = {J. Antibiot.}, year = 2011, } @article{CTT100615410, author = {Qingping Xu and Tadashi Eguchi and Irimpan I. Mathews and Christopher L. Rife and Hsiu-Ju Chiu and Carol L. Farr and Julie Feuerhelm and Lukasz Jaroszewski and Heath E. Klock and Mark W. Knuth and Mitchell D. Miller and Dana Weekes and Marc-André Elsliger and Ashley M. Deacon and Adam Godzik and Scott A. Lesley and Ian A. Wilson}, title = {Insights into Substrate Specificity of Geranylgeranyl Reductases Revealed by the Structure of Digeranylgeranylglycerophospholipid Reductase from Thermoplasma acidophilum, an Essential Enzyme in the Biosynthesis of Archaeal Membrane Lipids}, journal = {J. Mol. Biol.}, year = 2010, } @article{CTT100612951, author = {Hayato Fukuda and Shiina Nakamura and Tadashi Eguchi and Yoshiharu Iwabuchi and Naoki Kanoh}, title = {Concise Total Synthesis of Vicenistatin}, journal = {Synlett}, year = 2010, } @article{CTT100608685, author = {Fumitaka Kudo and Atsushi Motegi and Kazutoshi Mizoue and Tadashi Eguchi}, title = {Cloning and Characterization of the Biosynthetic Gene Cluster of 16-Membered Macrolide Antibiotic FD-891: Involvement of a Dual Functional Cytochrome P450 Monooxygenase Catalyzing Epoxidation and Hydroxylation}, journal = {ChemBioChem}, year = 2010, } @article{CTT100607805, author = {Hideyuki Tamegai and Hiroshi Sawada and Eriko Nango and Rie Aoki and Haruka Hirakawa and Teruhiko Iino and Tadashi Eguchi}, title = {Roles of 20 kDa Protein Associated with a Carbocycle-forming Enzyme Involved in Aminoglycoside Biosynthesis in Primary and Secondary Metabolism}, journal = {Biosci. Biotechnol. Biochem.}, year = 2010, } @article{CTT100596610, author = {Fumitaka Kudo and Hilda Sucipto and Tadashi Eguchi}, title = {Enzymatic Activity of a Glycosyltransferase KanM2 Encoded in the Kanamycin Biosynthetic Gene Cluster}, journal = {J. Antibiot.}, year = 2009, } @article{CTT100592893, author = {Fumitaka Kudo and Taiki Kawashima and Kenichi Yokoyama and Tadashi Eguchi}, title = {Enzymatic Preparation of Neomycin C from Ribostamycin}, journal = {J. Antibiot.}, year = 2009, } @article{CTT100591629, author = {Eriko Nango and Takashi Yamamoto and Takashi Kumasaka and Tadashi Eguchi}, title = {Crystal Structure of 3-Isopropylmalate Dehydrogenase in Complex with NAD+ and a Designed Inhibitor}, journal = {Bioorg. Med. Chem.}, year = 2009, } @article{CTT100590296, author = {Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthetic Genes for Aminoglycoside Antibiotics}, journal = {J. Antibiot.}, year = 2009, } @article{CTT100590291, author = {Susumu Inaba and Tadashi Eguchi and Atsushi Motegi and Kazutoshi Mizoue and Takeo Usui and Kazuo Nagai and Takao Kataoka}, title = {The Cytotoxic Macrolide FD-891 Induces Caspase-8-dependent Mitochondrial Release of Cytochrome c and Subsequent Apoptosis in Human Leukemia Jurkat Cells}, journal = {J. Antibiot.}, year = 2009, } @article{CTT100564692, author = {Kenichi Yokoyama and Daijiro Ohmori and Fumitaka Kudo and Tadashi Eguchi}, title = {Mechanistic Study on the Reaction of a Radical SAM Dehydrogenase BtrN by Electron Paramagnetic Resonance Spectroscopy}, journal = {Biochemistry}, year = 2008, } @article{CTT100558983, author = {Makoto Takaishi and Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthetic Pathway of 24-Membered Macrolactam Glycoside Incednine}, journal = {Tetrahedron}, year = 2008, } @article{CTT100558982, author = {Eriko Nango and Atsushi Minami and Takashi Kumasaka and Tadashi Eguchi}, title = {Crystallization and Preliminary X-ray Analysis of Vicenisaminyltransferase VinC}, journal = {Acta Cryst.}, year = 2008, } @article{CTT100554300, author = {Kenichi Yokoyama and Yasuhito Yamamoto and Fumitaka Kudo and Tadashi Eguchi}, title = {Involvement of Two Distinct N-Acetylglucosaminyltransferases and a Dual-Function Deacetylase in Neomycin Biosynthesis}, journal = {ChemBioChem}, year = 2008, } @article{CTT100552437, author = {Ying Lin and Jerome Volkman and Kenneth M. Nicholas and Takashi Yamamoto and Tadashi Eguchi and Susan L. Nimmo and Ann H. West and Paul F. Cook}, title = {Chemical Mechanism of Homoisocitrate Dehydrogenase from Saccharomyces cerevisiae}, journal = {Biochemistry}, year = 2008, } @article{CTT100552436, author = {Takashi Yamamoto and Tadashi Eguchi}, title = {Thiahomoisocitrate: A Highly Potent Inhibitor of Homoisocitrate Dehydrogenase Involved in the α-Aminoadipate Pathway}, journal = {Bioorg. Med. Chem.}, year = 2008, } @article{CTT100548277, author = {Eriko Nango and Takashi Kumasaka and Toshifumi Hirayama and Nobuo Tanaka and Tadashi Eguchi}, title = {Structure of 2-Deoxy-scyllo-inosose Synthase, a Key Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics, in Complex with a Mechanism-Based Inhibitor and NAD+}, journal = {Proteins}, year = 2008, } @article{CTT100546560, author = {Kenichi Yokoyama and Mario Numakura and Fumitaka Kudo and Daijiro Ohmori and Tadashi Eguchi}, title = {Characterization and Mechanistic Study of a Radical SAM Dehydrogenase in the Biosynthesis of Butirosin}, journal = {J. Am. Chem. Soc.}, year = 2007, } @article{CTT100544435, author = {Takeshi Hoshino and Tadashi Eguchi}, title = {Functional Analysis of Type 1 Isopentenyl Diphosphate Isomerase from Halobacterium sp. NRC-1}, journal = {Biosci. Biotechnol. Biochem.}, year = 2007, } @article{CTT100543115, author = {Fumitaka Kudo and Yuko Kasama and Toshifumi Hirayama and Tadashi Eguchi}, title = {Cloning of the Pactamycin Biosynthetic Gene Cluster and Characterization of a Crucial Glycosyltransferase prior to a Unique Cyclopentane Ring Formation}, journal = {J. Antibiot.}, year = 2007, } @article{CTT100551122, author = {Fumitaka Kudo and Takuya Fujii and Shunsuke Kinoshita and Tadashi Eguchi}, title = {Unique O-Ribosylation in the Biosynthesis of Butirosin}, journal = {Bioorg. Med. Chem.}, year = 2007, } @article{CTT100531578, author = {Toshifumi Hirayama and Fumitaka Kudo and Zhen Huang and Tadashi Eguchi}, title = {Role of Glutamate 243 in the Active Site of 2-Deoxy-scyllo-inosose Synthase from Bacilllus circulans}, journal = {Bioorg. Med. Chem.}, year = 2007, } @article{CTT100532833, author = {Atsushi Minami and Tadashi Eguchi}, title = {Substrate Flexibility of Vicenisaminyltransferase VinC Involved in the Biosynthesis of Vicenistatin}, journal = {J. Am. Chem. Soc.}, year = 2007, } @article{CTT100532105, author = {Takashi Yamamoto and Kentaro Miyazaki and Tadashi Eguchi}, title = {Substrate Specificity Analysis and Inhibitor Design of Homoisocitrate Dehydrogenase}, journal = {Bioorg. Med. Chem.}, year = 2007, } @article{CTT100532106, author = {Paul D. Fraser and Eugenia M. A. Enfissi and Michael Goodfellow and Tadashi Eguchi and Peter M. Bramley}, title = {Metabolite Profiling of Plant Carotenoids using the Matrix-assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry}, journal = {Plant J.}, year = 2007, } @article{CTT100532832, author = {Yuji Nishimura and Tadashi Eguchi}, title = {Stereochemistry of Reduction in Digeranylgeranylglycerophospholipid Reductase Involved in the Biosynthesis of Archaeal Membrane Lipids from Thermoplasma acidophilum}, journal = {Bioorg. Chem.}, year = 2007, } @article{CTT100533134, author = {Hiroyuki Morii and Tadashi Eguchi and Yosuke Koga}, title = {In vitro Biosynthesis of Ether-type Glycolipids in the Methanoarchaeon Methanothermobacter thermautotrophicus}, journal = {J. Bacteriol.}, year = 2007, } @article{CTT100531577, author = {Toshifumi Hirayama and Hideyuki Tamegai and Fumitaka Kudo and Kazumasa Kojima and Katsumi Kakinuma and Tadashi Eguchi}, title = {Biosynthesis of 2-Deoxystreptamine-containing Antibiotics in Streptoalloteichus hindudtanus JCM 3268: Characterization of 2-Deoxy-scyllo-inosose Synthase}, journal = {J. Antibiot.}, year = 2006, } @article{CTT100541861, author = {Fumitaka Kudo and Takashi Kitayama and Tadashi Eguchi and Katsumi Kakinuma}, title = {Macrolactam Formation Catalyzed by the Thioesterase Domain of Vicenistatin Polyketide Synthase}, journal = {Tetrahedron Lett.}, year = 2006, } @article{CTT100410282, author = {Takeshi Hoshino and Hideyuki Tamegai and Katsumi Kakinuma and Tadashi Eguchi}, title = {Inhibition of Type 2 Isopentenyl Diphosphate Isomerase from Methanocaldococcus jannaschii by a Mechanism-based Inhibitor of Type 1 Isopentenyl Diphosphate Isomerase}, journal = {Bioorg. Med. Chem.}, year = 2006, } @article{CTT100541866, author = {Shigehiro Tohyama and Katsumi Kakinuma and Tadashi Eguchi}, title = {The Complete Biosynthetic Gene Cluster of the 28-Membered Polyketide Macrolactones, Halstoctacosanolides, from Streptomyces halstedii HC34}, journal = {J. Antibiot.}, year = 2006, } @article{CTT100542378, author = {Yuji Nishimura and Tadashi Eguchi}, title = {Biosynthesis of Archaeal Membrane Lipids: Digeranylgeranylglycerophospholipid Reductase of the Thermoacidophilic Archaeon Thermoplasma acidophilum}, journal = {J. Biochem.}, year = 2006, } @article{CTT100541860, author = {Fumitaka Kudo and Yasuhito Yamamoto and Kenichi Yokoyama and Tadashi Eguchi and Katsumi Kakinuma}, title = {Biosynthesis of 2-Deoxystreptamine by Three Crucial Enzymes in Streptomyces fradiae NBRC12773}, journal = {J. Antibiot.}, year = 2005, } @article{CTT100540365, author = {Fumitaka Kudo and Mario Numakura and Hideyuki Tamegai and Hideki Yamamoto and Tadashi Eguchi and Katsumi Kakinuma}, title = {Extended Sequence and Functional Analysis of the Butirosin Biosynthetic Gene Cluster in Bacillus circulans SANK 72073}, journal = {J. Antibitot.}, year = 2005, } @article{CTT100540368, author = {Kenichi Yokoyama and Fumitaka Kudo and Mieko Kuwahara and Kousuke Inomata and Hideyuki Tamegai and Tadashi Eguchi and Katsumi Kakinuma}, title = {Stereochemical Recognition of Doubly Functional Aminotransferase in 2-Deoxystreptamine Biosynthesis}, journal = {J. Am. Chem. Soc.}, year = 2005, } @article{CTT100390189, author = {Fumitaka Kudo and Kenichi Kawabe and Hisako Kuriki and Tadashi Eguchi and Katsumi Kakinuma}, title = {A New family of Pathways for Glucose-1-phosphate/Glucosamine-1-phosphate Nucleotidylyltransferase in the Biosynthetic Antibiotics}, journal = {J. Am. Chem. Soc.}, year = 2005, } @article{CTT100390256, author = {Eriko Nango and Takashi Kumasaka and Takao Sato and Nobuo Tanaka and Katsumi Kakinuma and Tadashi Eguchi}, title = {Crystallization and X-ray Analysis of 2-Deoxy-scyllo-inosose Synthase, the Key Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics}, journal = {Acta Cryst.}, year = 2005, } @article{CTT100390250, author = {Zhen Huang and Katsumi Kakinuma and Tadashi Eguchi}, title = {Stereospecificity of Hydride Transfer in NAD+-Catalyzed 2-Deoxy-scyllo-inosose Synthase, the Key Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminocyclitol Antibiotics}, journal = {Bioorg. Chem.}, year = 2005, } @article{CTT100390252, author = {Tadashi Eguchi and Yasumasa Dekishima and Hideki Aizawa and Hideyuki Tamegai and Katsumi Kakinuma and Norihiko Misawa and Tomohisa Kuzuyama and Haruo Seto}, title = {Preparation of Highly Deuterated Zeaxanthin, Lycopene, and β-Carotene from Fully Deuterated Mevalonate using Engineered Escherichia coli}, journal = {Tetrahedron}, year = 2005, } @article{CTT100391449, author = {Tadashi Eguchi}, title = {Mevalonolactone-d9; A Versatile Tool for Biosynthetic Study of Isoprenoids. Synthesis and Its Application.}, journal = {J. Synth. Org. Chem. Jpn.}, year = 2005, } @article{CTT100390258, author = {Atsushi Minami and Katsumi Kakinuma and Tadashi Eguchi}, title = {Aglycon Switch Approach toward Unnatural Glycosides from Natural Glycoside with Glycosyltransferase VinC}, journal = {Tetrahedron Lett.}, year = 2005, } @article{CTT100390257, author = {Yasushi Ogasawara and Katsumi Kakinuma and Tadashi Eguchi}, title = {Involvement of Glutamate Mutase in the Biosynthesis of the Unique Starter Unit of the Macrolactam Polyketide Antibiotic Vicenistatin}, journal = {J. Antibiot.}, year = 2005, } @article{CTT100390254, author = {Atsushi Minami and Rei Uchida and Tadashi Eguchi and Katsumi Kakinuma}, title = {Enzymatic Approach to Unnatural Glycosides with Diverse Aglycon Scaffolds Using Glycosyltransferase VinC}, journal = {J. Am. Chem. Soc.}, year = 2005, } @article{CTT100499193, author = {Eriko NANGO and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Active Site Mapping of 2-Deoxy-scyllo-inosose Synthase, the Key Starter Enzyme for the Biosynthesis of 2-Deoxystreptamine. Mechanism-based Inhibition and Identification of Lysine-141 as the Entrapped Nucleophile}, journal = {J. Org. Chem.}, year = 2004, } @article{CTT100499195, author = {Tadashi EGUCHI and Keita YAMAMOTO and Kazutoshi MIZOUE and Katsumi KAKINUMA}, title = {Structure Revision of FD-891, a 16-Membered Macrolide Antibiotic}, journal = {J. Antibiot.}, year = 2004, } @article{CTT100539420, author = {Shigehiro TOHYAMA and Tadashi EGUCHI and Rabindra P. DHAKAL and Tomoyoshi AKASHI and Miyuki OTSUKA and Katsumi KAKINUMA}, title = {Genome-inspired Search for New Antibiotics. Isolation and Structure Determination of New 28-Membered Polyketide Macrolactones, Halstoctacosanolides A and B, from Streptomyces halstedii HC34}, journal = {Tetrahedron}, year = 2004, } @article{CTT100485247, author = {Eriko Nango and Fumitaka Kudo and Tadashi Eguchi and Katsumi Kakinuma}, title = {Reaction Stereochemistry of 2-Deoxy-scyllo-inosose Synthase. The Key Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics}, journal = {Chem. Lett.}, year = 2003, } @article{CTT100483172, author = {Tadashi EGUCHI and Yuji NISHIMURA and Katsumi KAKINUMA}, title = {Importance of the Isopropylidene Terminal of Geranylgeranyl Group for the Formation of Tetraether Lipid in Methanogenic Archaea}, journal = {Tetrahedron Lett.}, year = 2003, } @article{CTT100483175, author = {Tadashi EGUCHI and Eriko WATANABE and Katsumi KAKINUMA}, title = {Practical Enantioselective Synthesis of Fully Deuterated (R)-Mevalonolactone}, journal = {Tetrahedron}, year = 2003, } @article{CTT100483174, author = {Kentaro TAKEI and Yasumasa DEKISHIMA and Tadashi EGUCHI and Tomoyuki YAMAYA and Hitoshi SAKAKIBARA}, title = {A New Method for Enzymatic Preparation of Isopentenyladenine-type and trans-Zeatin-type Cytokinins with Radioisotope-labeling}, journal = {J. Plant. Res.}, year = 2003, } @article{CTT100506722, author = {Takashi YUKITA and Hiroshi NISHIDA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Biosynthesis of (2R)-4-Amino-2-hydroxybutyric Acid, Unique and Biologically Significant Substituent in }, journal = {J. Antibiot.}, year = 2003, } @article{CTT100538781, author = {Tadashi EGUCHI and Yasumasa DEKISHIMA and Yoshimitsu HAMANO and Tohru DAIRI and Haruo SETO and Katsumi KAKINUMA}, title = {A New Approach for the Investigation of Isoprenoid Biosynthesis Featuring Pathway Switching, Deuterium Hyperlabeling and 1H NMR Spectroscopy. The Reaction Mechanism of a Novel Streptomyces Diterpene Cyclase}, journal = {J. Org. Chem.}, year = 2003, } @article{CTT100479238, author = {H. Tamegai and T. Eguchi and K. Kakinuma}, title = {First Identification of Streptomyces Genes Involved in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics. Genetic and Evolutionary Analysis of L-Glutamine:2-Deoxy-scyllo-inosose Aminotransferase Genes}, journal = {J. Antibiot.}, year = 2002, } @article{CTT100468834, author = {Y. Matsushima and H. Itoh and T. Nakayama and S. Horiuchi and T. Eguchi and K. Kakinuma}, title = {Enantioselective Total Synthesis of Vicenistatin, a Novel 20-Membered Macrocyclic Lactam Antitumor Antibiotic}, journal = {Perkin 1}, year = 2002, } @article{CTT100468836, author = {H. Tamegai and E. Nango and M. Kuwahara and H. Yamamoto and Y. Ota and H. Kuriki and T. Eguchi and K. Kakinuma}, title = {Identification of L-Glutamine: 2-Deoxy-scyllo-inosose Aminotransferase Required for the Biosynthesis of Butirosin in Bacillus circulans}, journal = {J. Antibiot.}, year = 2002, } @article{CTT100468837, author = {T. Eguchi and K. Kobayashi and H. Uekusa and Y. Ohashi and K. Mizoue and Y. Matsushima and K. Kakinuma}, title = {Stereostructure of a Novel Cytotoxic 18-Membered Macrolactone Antibiotic FD-891}, journal = {Org. Lett.}, year = 2002, } @article{CTT100468835, author = {T. Eguchi and S. Sasaki and Z. Huang and K. Kakinuma}, title = {Importance of Specific Hydrogen-Bond Donor-Acceptor Interactions for the Key Carbocycle-forming Reaction Catalyzed by 2-Deoxy-scyllo-inosose Synthase in the Biosynthesis of 2-Deoxystreptamine-containing Aminocyclitol Antibiotics}, journal = {J. Org. Chem.}, year = 2002, } @article{CTT100450885, author = {Yoshitaka MATSUSHIMA and Takuya NAKAYAMA and Masaki FUJITA and Renuka BHANDARI and Tadashi EGUCHI and Kazutoshi SHINDO and Katsumi KAKINUMA}, title = {Isolation and Structure Elucidation of Vicenistatin M, and Importance of the Vicenisamine Aminosugar for Exerting Cytotoxicity of Vicenistatin}, journal = {J. Antibiot.}, year = 2001, } @article{CTT100450884, author = {Yoshitaka MATSUSHIMA and Takuya NAKAYAMA and Shigehiro TOHYAMA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Versatile Route to 2,6-Dideoxyaminosugars from Non-sugar Materials: Syntheses of Vicenisamine and Kedarosamine}, journal = {Perkin 1}, year = 2001, } @article{CTT100450883, author = {Kenji ARAKAWA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {36-Membered Macrocyclic Diether Lipid is Advantageous for Archaea to Thrive under the Extreme Thermal Environments}, journal = {Bull. Chem. Soc. Jpn.}, year = 2001, } @article{CTT100450882, author = {Katsumi KAKINUMA and Yasumasa DEKISHIMA and Yoshitaka MATSUSHIMA and Tadashi EGUCHI and Norihiko MISAWA and Motoki TAKAGI and Tomohisa KUZUYAMA and Haruo SETO}, title = {New Approach to Multiply Deuterated Isoprenoids Using Triply Engineered Escherichia coli and Its Potential as a Tool for Mechanistic Enzymology}, journal = {J. Am. Chem. Soc.}, year = 2001, } @article{CTT100450886, author = {Yasumasa DEKISHIMA and Tadashi EGUCHI and Katsumi KAKINUMA and Yoshitaka MATSUSHIMA and Norihiko MISAWA and Motoki TAKAGI and Tomohisa KUZUYAMA and Haruo SETO}, title = {Preparation of Multiply Deuterated Carotenoid by Triply Engineered Escherichia coli with Perdeuterated Mevalonate}, journal = {Carotenoid Science}, year = 2001, } @article{CTT100450887, author = {Kenji ARAKAWA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Highly Thermostable Liposome from 72-Membered Macrocyclic Tetraether Lipid. Importance of 72-Membered Lipid for Archaea to Thrive under Hyperthermal Environments}, journal = {Chem. Lett.}, year = 2001, } @article{CTT100450888, author = {Hiroshi NISHIDA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Amino Acid Starter Unit in the Biosynthesis of Macrolactam Polyketide Antitumor Antibiotic Vicenistatin}, journal = {Tetrahedron}, year = 2001, } @article{CTT100468833, author = {M. Fujita and H. Tamegai and T. Eguchi and K. Kakinuma}, title = {Novel Sustrate-specificity of Designer 3-Isopropylmalate Dehydrogenase Derived from Thermus thermophilus HB-8}, journal = {Biosci. Biotechnol. Biochem.}, year = 2001, } @article{CTT100485251, author = {Yasumasa Ota and Hideyuki Tamegai and Fumitaka Kudo and Hisako Kuriki and Aumi Koike-Takeshita and Tadashi Eguchi and Katsumi Kakinuma}, title = {Butirosin-biosynthetic Gene Cluster from Bacillus circulans}, journal = {J. Antibiot.}, year = 2000, } @article{CTT100485252, author = {Katsumi Kakinuma and Eriko Nango and Fumitaka Kudo and Yoshitaka Matsushima and Tadashi Eguchi}, title = {An Expeditious Chemo-enzymatic Route from Glucose to Catechol by the Use of 2-Deoxy-scyllo-inosose Synthase}, journal = {Tetrahedron Letters}, year = 2000, } @article{CTT100435351, author = {Tadashi EGUCHI and Kenji ARAKAWA and Katsumi KAKINUMA and Sangita GHOSH and Yoichi NAKATANI and Guy OURISSON}, title = {Giant Vesicles from 72-Membered Macrocyclic Archaeal Phospholipid Analogues: Initiation of Vesicle Formation by Molecular Recognition between Membrane Components}, journal = {Chem. Eur. J.}, year = 2000, } @article{CTT100444596, author = {Jun OGIHARA and Jun KATO and Kunio OISHI and Yoshinori FUJIMOTO and Tadashi EGUCHI}, title = {Production and Structural Analysis of PP-V, A Homologue of Monascorubramine, Produced by a New Isolate of Penicillium sp.}, journal = {J. Biosci. Bioeng.}, year = 2000, } @article{CTT100435353, author = {Miyuki OTSUKA and Masaki FUJITA and Yoshitaka MATSUSHIMA and Tadashi EGUCHI and Kazutoshi SHINDO and Katsumi KAKINUMA}, title = {Biosynthetic Pathway of Macrolactam Polyketide Glycoside Antitumor Antibiotic Vicenistatins}, journal = {Tetrahedron}, year = 2000, } @article{CTT100435352, author = {Tadashi EGUCHI and Shinobu KANAI and Katsumi KAKINUMA and Tadayasu OKAZAKI and Kazutoshi MIZOUE}, title = {Synthesis of NG-061 and its Analogs, and Their Biological Evaluation as an Enhancer of Nerve Growth Factor}, journal = {Chem. Pharm. Bull.}, year = 2000, } @article{CTT100435350, author = {Tadashi EGUCHI and Hayato TAKYO and Mikio MORITA and Katsumi KAKINUMA and Yosuke KOGA}, title = {Unusual Double-Bond Migration as Plausible Key Reaction in the Biosynthesis of the Isoprenoidal Membrane Lipids of Methanogenic Archaea}, journal = {Chem. Commun.}, year = 2000, } @article{CTT100435349, author = {Masaaki FUJITA and Yumiko TOYOOKA and Hideyuki TAMEGAI and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Arg-94 is Crucial to the Catalysis of 3-Isopropylmalate Dehydrogenase from Thermus thermophilus HB8}, journal = {J. Mol. Cat. B}, year = 2000, } @article{CTT100435348, author = {Kazuhiro TANAKA and Erko STACKEBRANDT and Shigehiro TOHYAMA and Tadashi EGUCHI}, title = {Desulfovirga adipica gen. nov., sp. nov., an Adipate-degrading, Gram-negative, Sulfate-reducing Bacterium}, journal = {Int. J. Syst. Evol. Microbiol.}, year = 2000, } @article{CTT100435346, author = {Olivier DANNENMULLER and Kenji ARAKAWA and Tadashi EGUCHI and Katsumi KAKINUMA and Sylvie BLANC and Anne-Marie ALBRECHT and Marc SCHMUTZ and Yoichi NAKATANI and Guy OURISSON}, title = {Membrane Properties of Archaeal Macrocyclic Diether Phospholipids}, journal = {Chem. Eur. J.}, year = 2000, } @article{CTT100444764, author = {J. Ogihara and J. Kato and K. Oishi and Y. Fujimoto and T. Euchi}, title = {Production and structural analysis of PP-V, a homologue of monascorubramine, produced by a new isolate of Penicillium sp.}, journal = {J. Biosci. Bioeng.}, year = 2000, } @article{CTT100430115, author = {江口正 and 荒川賢治 and 柿沼勝己}, title = {30員環を越す巨大な環状化合物の合成:古細菌細胞膜の脂質分子を中心として}, journal = {有機合成化学協会誌}, year = 1999, } @article{CTT100426142, author = {Akira CHIBA and Noriko ARAI and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {3-Isopropylidenemalic Acid: A Mechanism-based Inhibitor of 3-Isopropylmalate Dehydrogenase}, journal = {Chem. Lett.}, year = 1999, } @article{CTT100422600, author = {Akira CHIBA and Tadashi EGUCHI and Tairo OSHIMA and Katsumi KAKINUMA}, title = {Synthesis of Cyclopropane Substrate Analog for Isopropylmalate Dehydrogenase and Its Inhibition Mechanism}, journal = {Tetrahedron}, year = 1999, } @article{CTT100422602, author = {Renuka BHANDARI and Tadashi EGUCHI and Akiko SEKINE and Yuji OHASHI and Katsumi KAKINUMA and Mayumi ITO and Kazutoshi MIZOUE}, title = {Structure of NG-061, A Novel Potentiator of Nerve Growth Factor (NGF) Isolated from Penicillium minioluteum F-4627}, journal = {J. Antibiot.}, year = 1999, } @article{CTT100422601, author = {M. ITO and N. SAKAI and K. ITO and F. MIZOBE and K. HARADA and K. MIZOUE and R. BHANDARI and T. EGUCHI and K. Kakinuma}, title = {A Novel Fungal Metabolite NG-061 Enhances and Mimics Neurotrophic Effect of Nerve Growth Factor (NGF) on Neurite Outgrowth in PC12 Cells}, journal = {J. Antibiot.}, year = 1999, } @article{CTT100422605, author = {Akira CHIBA and Tadashi EGUCHI and Tairo OSHIMA and Katsumi KAKINUMA}, title = {Coenzyme Activity of NAD Analogs for 3-Isopropylmalate Dehydrogenase from Thermus thermophilus HB8}, journal = {Biosci. Biotechnol. Biochem.}, year = 1999, } @article{CTT100422604, author = {Akira CHIBA and Tetsuya AOYAMA and Rieko SUZUKI and Tadashi EGUCHI and Tairo OSHIMA and Katsumi KAKINUMA}, title = {Synthetic and Mechanistic Studies of (2R,3S)-3-Vinylmalic Acid as a Mechanism-Based Inhibitor of 3-Isopropylmalate Dehydrogenase}, journal = {J. Org. Chem.}, year = 1999, } @article{CTT100422603, author = {Kenji ARAKAWA and Hiroki KANO and Tadashi EGUCHI and Yayoi NISHIYAMA and Katsumi KAKINUMA}, title = {Significance of the 72-Membered Macrocyclic Structure Found in Archaeal Membrane Lipids: Model Studies of the Macrocyclic Tetraether Diphospholipids by Calorimetric, 31P NMR, and Electron Microscopic Analyses}, journal = {Bull. Chem. Soc. Jpn.}, year = 1999, } @article{CTT100384651, author = {Tadashi EGUCHI and Katsuya KONDO and Katsumi KAKINUMA and Hidehiro UEKUSA and Yuji OHASHI and Kazutoshi MIZOUE and Ya-Fang QIAO}, title = {Unique Solvent-Dependent Atropisomerism of a Novel Cytotoxic Naphthoxanthene Antibiotic FD-594}, journal = {J. Org. Chem.}, year = 1999, } @article{CTT100384643, author = {Ya-Fang QIAO and Tadayasu OKAZAKI and Tsutomu ANDO and Kazutoshi MIZOUE and Katsuya KONDO and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Isolation and Characterization of a New Pyrano[4',3':6,7]naphtho[1,2-b]xanthene Antibiotic FD-594}, journal = {J. Antibiot.}, year = 1998, } @article{CTT100384641, author = {Hideyuki MATSUNAMI and Hiroshi KAWAGUCHI and Kenji INAGAKI and Tadashi EGUCHI and Katsumi KAKINUMA and Hideyuki TANAKA}, title = {Overproduction and Substrate Specificity of 3-Isopropylmalate Dehydrogenase from Thiobacillus ferrooxidans}, journal = {Biosci. Biotechnol. Biochem.}, year = 1998, } @article{CTT100422596, author = {Kenji Arakawa and Tadashi Eguchi and Katsumi Kakinuma}, title = {Specific Deuterium Labeling of Archaeal 36-Membered Macrocyclic Diether Lipid}, journal = {Bull. Chem. Soc. Jpn.}, year = 1998, } @article{CTT100422595, author = {Kenji ARAKAWA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {An Olefin Metathesis Approach to 36- and 72-Membered Archaeal Macrocyclic Membrane Lipids}, journal = {J. Org. Chem.}, year = 1998, } @article{CTT100384653, author = {Kenji ARAKAWA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Tightly Packed Membranes Composed of 36-Membered Macrocyclic Diether Phospholipid Found in Archaea Growing under Deep-sea Hydrothermal Vents}, journal = {Chem. Lett.}, year = 1998, } @article{CTT100384652, author = {Yoshitaka MATSUSHIMA and Hiroaki ITOHh and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Enantioselective and Convergent Synthesis of the 20-Membered Lactam Aglycon of Vicenistatin Antitumor Antibiotic}, journal = {J. Antibiot.}, year = 1998, } @article{CTT100384650, author = {Tadashi EGUCHI and Mikio MORITA and Katsumi KAKINUMA}, title = {Multigram Synthesis of Mevalonolactone-d9 and Its Application to Stereochemical Analysis by 1H NMR of the Saturation Reaction in the Biosynthesis of the 2, 3-Di-O-phytanyl-sn-glycerol Core of the Archaeal Membrane Lipid}, journal = {J. Am. Chem. Soc.}, year = 1998, } @article{CTT100384649, author = {Noriaki YAMAUCHI and Masashi KISHIDA and Keiju SAWADA and Yuji OHASHI and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Solvent-dependent Stereochemical Anomaly in the Nucleophilic Addition of Ester-derived Enolate to Bicyclo[3, 3, 0]octan-2-one System of Diacetone Glucose-3-ulose}, journal = {Chem. Lett.}, year = 1998, } @article{CTT100384648, author = {Miyuki OTSUKA and Tadashi EGUCHI and Kazutoshi SHINDO and Katsumi KAKINUMA}, title = {Non-Fatty Acyl Polyketide Starter in the Biosynthesis of Vicenistatin, an Antitumor Macrolactam Antibiotic}, journal = {Tetrahedron Lett.}, year = 1998, } @article{CTT100384647, author = {Hiroko ARAI and Yoshitaka MATSUSHIMA and Tadashi EGUCHI and Kazutoshi SHINDO and Katsumi KAKINUMA}, title = {Absolute Stereochemistry of Vicenistatin, a Novel 20-Membered Macrocyclic Lactam Antitumor Antibiotic}, journal = {Tetrahedron Lett.}, year = 1998, } @article{CTT100384646, author = {Tadashi EGUCHI and Kazuya IBARAGI and Katsumi KAKINUMA}, title = {Total Synthesis of Archaeal 72-Membered Macrocyclic Tetraether Lipids}, journal = {J. Org. Chem.}, year = 1998, } @article{CTT100384645, author = {Mikio MORITA and Noriaki YAMAUCHI and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Structural Diversity of Membrane Core Lipid of Extreme Halophiles}, journal = {Biosci. Biotechnol. Biochem.}, year = 1998, } @article{CTT100384644, author = {Katsuya KONDO and Tadashi EGUCHI and Katsumi KAKINUMA and Kazutoshi MIZOUE and Ya-Fang QIAO}, title = {Structure and Biosynthesis of FD-594 ; a New Antitumor Atibiotic}, journal = {J. Antibiot.}, year = 1998, } @article{CTT100384642, author = {Hiroyuki MORII and Tadashi EGUCHI and Masateru NISHIHARA and Katsumi KAKINUMA and Helmut KONIG and Yosuke KOGA}, title = {A Novel Ether Core Lipid with an H-Shaped C┣D280┫D2-Isoprenoid Hydrocarbon Chain from the Hyperthermophilic Methanogen Methanothermus fervidus}, journal = {Biochim. Biophys. Acta}, year = 1998, } @article{CTT100384639, author = {Tadashi EGUCHI and Miki FUKUDA and Yumiko TOYOOKA and Katsumi KAKINUMA}, title = {Rational De Nove Design of NADH Mimic for Stereoselective Reduction Based on Molecular Orbital Calculation}, journal = {Tetrahedron}, year = 1998, } @article{CTT100384640, author = {Kazuhiro TAGUCHI and Kenji ARAKAWA and Tadashi EGUCHI and Katsumi KAKINUMA and Yoichi NAKATANI and Guy OURISSON}, title = {Synthesis of Macrocyclic Phosphates as Models of Archaeal Membrane Lipids. Monolayer and Bilayer Studies}, journal = {New J. Chem.}, year = 1998, } @article{CTT100384636, author = {Masashi KISHIDA and Noriaki YAMAUCHI and Keiju SAWADA and Yuji OHASHI and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Enantioselective Synthesis of(R)-Mevalonolactone and(R)-Mevalonolactone-d┣D29┫D2 on Carbohydrate Template}, journal = {Perkin 1}, year = 1997, } @article{CTT100384635, author = {Akira CHIBA and Tadashi EGUCHI and Tairo OSHIMA and Katsumi KAKINUMA}, title = {Synthesis of Conformationally Restricted Substrate Analogs and Their Interaction with 3-Isopropylmalate Dehydrogenase Derived from Thermus thermophilus}, journal = {Tetrahedron}, year = 1997, } @article{CTT100384637, author = {Tadashi EGUCHI and Kenji ARAKAWA and Takumi TERACHI and Katsumi KAKINUMA}, title = {Total Synthesis of Archaeal 36-Membered Macrocyclic Diether Lipid}, journal = {J. Org. Chem.}, year = 1997, } @article{CTT100384638, author = {Tadashi EGUCHI and Hiroki KANO and Kenji ARAKAWA and Katsumi KAKINUMA}, title = {Synthetic Studies of Archaeal Macrocyclic Tetraether Lipids : Practical Synthesis of 72-Membered Tetraether Model Compounds}, journal = {Bull. Chem. Soc. Jpn.}, year = 1997, } @article{CTT100384634, author = {Yutaka MAEDA and Keiko TAGO and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {A Versatile Synthon for Chirally β-Deuterated L-Amino Acids and Synthesis of(3R)-and(3S)-[3-┣D12┫D1H┣D21┫D2]-L-Serine}, journal = {Biosci. Biotech. Biochem.}, year = 1996, } @article{CTT100384633, author = {Masashi KISHIDA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Remote Asymmetric Induction Observed in the Alkylation of Propionate Attached to a Carbohydrate Template}, journal = {Tetrahedron Lett.}, year = 1996, } @article{CTT100384632, author = {Tadashi EGUCHI and Hiroki KANO and Katsumi KAKINUMA}, title = {Synthetic Study on Archaeal Macrocyclic Tetraether Lipids-A Versatile Approach to Desmethylated Analogs of 72-Membered Dibiphytanyldiglycerol}, journal = {Chem. Commun.}, year = 1996, } @article{CTT100384631, author = {Tetsuya AOYAMA and Tadashi EGUCHI and Tairo OSHIMA and Katsumi KAKINUMA}, title = {Synthesis of DL-threo-3-(1-Fluoro-1-methylethyl)-and DL-threo-3-(1,1-Difluoroethyl)malic Acids. Mechanistic Studies of 3-Isopropylmalate Dehydrogenase}, journal = {J. Chem. Soc. Perkin 1}, year = 1995, } @article{CTT100384630, author = {Yumiko TOYOOKA and Toshihiro MATSUZAWA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {NADH Mimics on Diacetone-D-glucose : Stereoselective Biomimetic Reduction of Benzoylformate and Interpretation of Chirality Transfer Deduced by Molecular Orbital Approach}, journal = {Tetrahedron}, year = 1995, } @article{CTT100402380, author = {Y. Fujimoto and C. Murasaki and T. Eguchi and K. Kakinuma and C. P. Dutta}, title = {Formation of 9,25-cyclofernane by reductive homoallylic cyclization of fern-9(11)-en-25-ol mesylate}, journal = {Chem. Pharm. Bull.}, year = 1994, } @article{CTT100402378, author = {M. Sahai and M. Singh and Y. K. Gupta and S. Akashi and R. Yuji and K. Hirayama and H. Asaki and H. Araya and N. Hara and T. Eguchi and K. Kakinuma and Y. Fujimoto}, title = {Annonaceous acetogenins from the seeds of Annona squamosa. Adjacent bis-tetrahydrofuranic acetogenins}, journal = {Chem. Pharm. Bull.}, year = 1994, } @article{CTT100384625, author = {Noriaki YAMAUCHI and Takumi TERACHI and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Mechanistic and Stereochemical Studies on Ferrier Reaction by Means of Chirally Deuterated Glucose}, journal = {Tetrahedron}, year = 1994, } @article{CTT100384629, author = {Yasuyuki TAKENAKA and Tetsuya AOYAMA and Tadashi EGUCHI and Yuji OHASHI and Katsumi KAKINUMA}, title = {Structure of Ethyl (2S┣D1*┫D1, 3R┣D1*┫D1)-2-Benzoyloxy-4,4-difluoro-3-(4-methoxyphenyl)pentanoate}, journal = {Analytical Science}, year = 1994, } @article{CTT100384628, author = {Yoshinori FUJIMOTO and Chikako MURASAKI and Tadashi EGUCHI and Katsumi KAKINUMA and C. P. DUTTA}, title = {Formation of 9,25-Cyclofernance by Reductive Homoallylic Cyclization of Fern-9(11)-en-25-ol Mesylate}, journal = {Chem. Pharm. Bull.}, year = 1994, } @article{CTT100384627, author = {M. SAHAI and S. SINGH and M. SINGH and Y. K. GUPTA and S. AKASHI and R. YUJI and K. Hirayama and H. ASAKI and H. ARAYA and N. HARA and T. EGUCHI}, title = {Annonaceous Acetogenins from the Seed of Annona Squamosa. Adjacent Bistetrahydofuraanic Acetogenins}, journal = {Chem. Pharm. Bull.}, year = 1994, } @article{CTT100384626, author = {Hiroaki TERASAWA and Kentaro MIYAZAKI and Tairo OSHIMA and Tadashi EGUCHI and Katsumi KAKINUMA}, title = {Synthesis of 2-O-Methyl Ether and 1-Carboxamide Derivatives of (2R,3S)-3-Isopropylmalic Acid and Their Interaction with Thermophilic 3-Isopropylmalate Dehydrogenase}, journal = {Biosci. Biotech. Biochem.}, year = 1994, } @article{CTT100402015, author = {C. P. Dutta and J. Banerjee and G. Datta and U. K. Som and T. Eguchi and C. Murasaki and K. Kakinuma and Y. Fujimoto}, title = {Tuberosic acid, a pentacyclic triterpene from Nephrolepsis tuberosa}, journal = {Phytochemistry}, year = 1993, } @article{CTT100402014, author = {J. Mungarulire and R. M. Munabu and C. Murasaki and T. Eguchi and Y. Fujimoto and K. Kakinuma and K. Kobayashi and M. Uramoto and N. Ikekawa}, title = {A novel steroidal saponin, pogosterol from Vernonia pogosperma}, journal = {Chem. Pharm. Bull.}, year = 1993, } @article{CTT100384623, author = {Osamu KIKUCHI and Tadashi EGUCHI and Katsumi KAKINUMA and Yasuhiko KOEZUKA and Kazutoshi SHINDO and Noboru OTAKE}, title = {Chemical Modification of Gilvocarcin V. Modification of the Side Chain}, journal = {J. Antibiot.}, year = 1993, } @article{CTT100384624, author = {C. P. DUTTA and J. BANERJEE and G. DATTA and U. K. SOM and Tadashi EGUCHI and Chikako MURASAKI and Katsumi KAKINUMA and Yoshinori FUJIMOTO}, title = {Tuberosic Acid, A Pentacyclic Triterpene from Nephrolepsis tuberosa}, journal = {Phytochemistry}, year = 1993, } @article{CTT100384620, author = {J. MUNGARULIRE and R. M. MUNABU and C. MURASAKI and T. EGUCHI and Y. FUJIMOTO and K. KAKINUMA and K. Kobayashi and M. Uramoto and N. Ikekakwa}, title = {A Novel Steroidal Sapogenin, Pogosterol from Vernonia pogosperma}, journal = {Chem. Pharm Bull.}, year = 1993, } @article{CTT100384622, author = {Tadashi EGUCHI and Takashi KOUDATE and Katsumi KAKINUMA}, title = {The Overman Rearrangement on a Diacetone-D-Glucose Template : Kinetic and Theoretical Studies on the Chirality Transcription}, journal = {Tetrahedron}, year = 1993, } @article{CTT100384621, author = {Tadashi EGUCHI and Takumi TERACHI and Katsumi KAKINUMA}, title = {Direct Closure of a 36-Membered Ring Using the McMurry Coupling : Synthetic Studies on Archaebacterial Macrocyclic Membrane Lipids}, journal = {Tetrahedron Lett.}, year = 1993, } @article{CTT100384619, author = {Mitsuzi YOSHIDA and Yoko TANAKA and Tadashi EGUCHI and Nobuo IKEKAWA and Nagahiro SAIJO}, title = {Effect of Hexafluoro-1,25-dihydroxyvitamin D┣D23┫D2 and Sodium Butyrate Combination on Differentiation and Proliferation of HL-60 Leukemia Cells}, journal = {Anticancer Research}, year = 1992, } @article{CTT100384609, author = {Tadashi EGUCHI and Tetsuya AOYAMA and Katsumi KAKINUMA}, title = {Remarkable Reversal of Stereoselectivity in Witting-Type Olefinations of α-Fluorinated Alkyl Aryl Ketones}, journal = {Tetrahedron Letters}, year = 1992, } @article{CTT100384618, author = {Katsumi KAKINUMA and Izumi TAKAGI and Tadashi EGUCHI}, title = {Stereochemistry in the Triose-phosphate Isomerase Reaction in Archabacteria Halobacterium halobium}, journal = {Tetrahedron Lett.}, year = 1992, } @article{CTT100384610, author = {Katsumi KAKINUMA and Takashi KOUDATE and Hui-Yin. LI and Tadashi EGUCHI}, title = {Enantiocontrol Intrinsic Antiparallel Double Repulsion on Diacetone-D-glucose Template. Enantioselective Synthesis of Alanine and Chirally Deuterated Glycine}, journal = {Tetrahedron Letters}, year = 1991, } @article{CTT100384611, author = {Katsumi KAKINUMA and Toshihiro MATSUZAWA and Tadashi EGUCHI}, title = {Diacetone Glucose Architecture as a Chirality Template I. Crucial Effects of the Intramolecular Oxygens upon the LiAlH┣D24┫D2 Reduction of the Propargyl Alcohol of the 3-C-Ethynyl-1,2 : 5,6-di-O-isopropylidene-α-D-allofuranose Derivatives}, journal = {Tetrahedron}, year = 1991, } @article{CTT100402310, author = {J. Banerjee and G. Datta and C. P. Dutta and T. Eguchi and Y. Fujimoto and K. Kakinuma}, title = {Fern-9(11)-en-25-oic acid, a triterpene from Adiantum venustum}, journal = {Phytochemistry}, year = 1991, } @article{CTT100402313, author = {Y. Fujimoto and T. Eguchi and C. Murasaki and Y. Ohashi and K. Kakinuma and H. Takagaki and M. Abe and K. Inazawa and K. Yamazaki and N. Ikekawa and O. Yoshikawa and T. Ikekawa}, title = {Studies on the structure and stereochemistry of cytotoxic furanonaphthoquinones from Tabebuia impetiginosa: 5- and 8-hydroxy-2-(1-hydroxyethyl)naphtho[2,3-b]furan-4,9-diones}, journal = {J. Chem. Soc., Perkin Trans. 1}, year = 1991, } @article{CTT100384614, author = {Y. FUJIMOTO and C. MURASAKI and K. KAKINUMA and T. EGUCHI and N. IKEKAWA and M. FURUYA and K. HIRAYAMA and T. IKEKAWA and M. SAHAI and Y. K. GUPTA}, title = {Squamostatin-A : Unprecedented Bis-tetrahydrofuran Acetogenin from Annona squamosa}, journal = {Tetrahedron Letters}, year = 1990, } @article{CTT100384612, author = {Tadashi EGUCHI and Hui-Yin LI and Jun-ichi KAZAMI and Katsumi KAKINUMA and Noboru OTAKE}, title = {Intermolecular Stacking of Gilvocarcin V Tetraacetate as Evidenced by Nuclear Magnetic Resonance Studies}, journal = {Journal of Antibiotics}, year = 1990, } @article{CTT100384613, author = {TADASHI EGUCHI}, title = {Conformational Analysis of 1α, 25-Dihydroxyvitamin D┣D23┫D2 by Nuclear Magnetic Resonance}, journal = {Bioorganic Chemistry}, year = 1990, } @article{CTT100399731, author = {Y. Fujimoto and K. Kakinuma and T. Eguchi and N. Ikekawa and N. Hirayama and A. Mbarushimana and D. Ntahomvukiye}, title = {12,15-Dihydroxylabda-8(17),13-dien-19-oic acid from Guizotia scabra}, journal = {Phytochemistry}, year = 1990, } @article{CTT100389783, author = {Y. Fujimoto and C. Murasaki and K. Kakinuma and T. Eguchi and N. Ikekawa and M. Furuya and K. Hirayama and T. Ikekawa and M. Sahai and Y. K. Gupta and A. B. Ray}, title = {Squamostatin-A: Unprecedented bis-tetrahydrofuran acetogenin from Annona squamosa}, journal = {Tetrahedron Lett.}, year = 1990, } @article{CTT100384615, author = {Tadashi EGUCHI and Mitsuji YOSHIDA and Nobuo IKEKAWA}, title = {Synthesis and Biological Activities of 22-Hydroxy and 22-Methoxy Derivatives of 1α, 25-Dihydroxyvitamin D┣D23┫D2 : Importance of Side Chain Conformation for Biological Activities}, journal = {Bioorganic Chemistry}, year = 1989, } @article{CTT100399717, author = {Y. Fujimoto and T. Eguchi and K. Kakinuma and N. Ikekawa and M. Sahai and Y. K. Gupta}, title = {Squamocin, a new cytotoxic bis-tetrahydrofuran containing acetogenin from Annona squamosa}, journal = {Chem. Pharm. Bull.}, year = 1988, } @article{CTT100399712, author = {T. Eguchi and Y. Fujimoto and K. Kakinuma and N. Ikekawa and M. Sahai and M. P. Verma and Y. K. Gupta}, title = {23-Hydroxyphysalolactone, a new withanolide with a 23-hydroxyl group from Physalis peruviana (Solanaceae)}, journal = {Chem. Pharm. Bull.}, year = 1988, } @article{CTT100506572, author = {Tadashi EGUCHI and Yoshinori FUJIMOTO and Katsumi KAKINUMA and Nobuo IKEKAWA and Mahendra SAHAI}, title = {23-Hydroxyphysalolactone, a New Withanolide with a 23-Hydroxyl Group from Physalis peruviana(Solanaceae)}, journal = {Munna P. VERMA, Yogesh K. GUPTA}, year = 1988, } @article{CTT100384616, author = {Tadashi EGUCHI and Suguru TAKATSUTO and Masaji ISHIGURO and Nobuo IKEKAWA and Yoko TANAKA and Hector F. DELUCA}, title = {Synthesis and Determination of Configuration of Natural 25-Hydroxyvitamin D┣D23┫D2 26,23-lactone}, journal = {Proceedings of the Natinal Academy of Science of the United States of America}, year = 1981, } @article{CTT100384617, author = {Yoko TANAKA and Hector F. DELUCA and Heinrich K. SCHNOES and Nobuo IKEKAWA and Tadashi EGUCHI}, title = {23,25-Dihydroxyvitamin D┣D23┫D2 : A Natural Precursor in the Biosynthesis of 25-Hydroxyvitamin D┣D23┫D2-26,23-lactone}, journal = {Proceedings of the Natinal Academy of Science of the United States of America}, year = 1981, } @inproceedings{CTT100895306, author = {Kaede Kotagiri and Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Protein-protein interaction between dehydratase and acyl carrier protein in the biosynthesis of macrolactam antibiotic cremimycin}, booktitle = {}, year = 2023, } @inproceedings{CTT100895304, author = {Kentaro Hirano and Hiroaki Kishikawa and Kazuma Tsuboi and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロライド抗生物質FD-891 と virustomycin Aの生合成遺伝子改変}, booktitle = {}, year = 2023, } @inproceedings{CTT100895303, author = {Taiga Yokouchi and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ビリデノマイシンの生合成研究}, booktitle = {}, year = 2023, } @inproceedings{CTT100895302, author = {Dawei Wang and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ヒタチマイシン生合成におけるアデニル化酵素HitBの基質特異性の改変}, booktitle = {}, year = 2023, } @inproceedings{CTT100895301, author = {Mutsumi Ikezaki and Kazuma Tsuboi and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ヒタチマイシン生合成における脱水素酵素HitM4の構造機能解析}, booktitle = {}, year = 2023, } @inproceedings{CTT100895300, author = {Rina Yasutomi and Fumitaka Kudo and Tadashi Eguchi}, title = {アミノグリコシド系抗生物質イスタマイシンとスポラリシンの生合成研究}, booktitle = {}, year = 2023, } @inproceedings{CTT100895299, author = {Aoi Sakamoto and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {アミノグリコシド系抗生物質4′-デオキシブチロシンの生合成研究}, booktitle = {}, year = 2023, } @inproceedings{CTT100895305, author = {Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Protein-protein interaction between ketosynthase-like decarboxylase and acyl carrier protein in type I polyketide synthases}, booktitle = {}, year = 2023, } @inproceedings{CTT100883608, author = {野原麻耶 and 宮野夏妃 and 倉本怜季 and Akimasa Miyanaga and 木下佳奈 and 石川文洋 and 高島克輝 and Fumitaka Kudo and Tadashi Eguchi and 田邉元三}, title = {拡張型基質結合部位をもつアデニル化酵素の機能·構造解析および非天然型誘導体合成への応用}, booktitle = {}, year = 2022, } @inproceedings{CTT100883607, author = {Akimasa Miyanaga and 高橋壯太朗 and Koichi Kawamura and Shohei Kurihara and Yuichiro Nakazawa and Naeko Iwai and 南雲陽子 and 臼井健郎 and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ヒタチマイシンの生合成研究}, booktitle = {}, year = 2022, } @inproceedings{CTT100877479, author = {Fumitaka Kudo and Michel Rohmer and TADASHI EGUCHI}, title = {Biosynthesis of bacteriohopanepolyols: characterization of radical SAM adenosylation enzyme HpnH}, booktitle = {}, year = 2022, } @inproceedings{CTT100877510, author = {Naeko Iwai and Yoko Nagumo and Fumitaka Kudo and Tadashi Eguchi and Takeo Usui}, title = {Studies on the mechanism of plasma membrane disruption by hitachimycin}, booktitle = {}, year = 2022, } @inproceedings{CTT100877507, author = {Atsushi Minato and Shusuke Sato and Chitose Maruyama and Yoshimitsu Hamano and Fumitaka Kudo and Tadashi Eguchi}, title = {1-アミノ-2-メチルシクロプロパンカルボン酸生合成におけるメチル基転移酵素の機能解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100869563, author = {Mizuki Nambu and Takuji Chikuma and 岩﨑有紘 and 末永聖武 and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {リングビアペプチンB推定生合成遺伝子クラスター中の二鉄含有酸化酵素の機能解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100869562, author = {Masato Fushimi and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {I型ポリケチド合成酵素における同一モジュールのアシル基転移酵素とアシルキャリアタンパク質の相互作用解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100869561, author = {Kenji Nagata and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質生合成におけるアデニル化酵素とアシルキャリアタンパク質間の相互作用解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100869560, author = {Akira Nagai and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {I型ポリケチド合成酵素ローディングモジュールにおけるケト合成酵素様脱炭酸酵素の変異体解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100869559, author = {Taichi Chisuga and Akira Nagai and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {I型ポリケチド合成酵素ローディングモジュールにおけるケト合成酵素様脱炭酸酵素の機能構造解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100877497, author = {Shusuke Sato and Fumitaka Kudo and Michel Rohmer and Tadashi Egchi}, title = {Characterization of Radical SAM Adenosylhopane Synthase HpnH in the Biosynthesis of C35 Bacteriohopanepolyols}, booktitle = {}, year = 2021, } @inproceedings{CTT100858451, author = {Fumitaka Kudo and Yukinobu Kitayama and Akimasa Miyanaga and Tadashi Eguchi}, title = {Kanamycin biosynthesis – Post-glycosylation modification of sugar moieties}, booktitle = {}, year = 2021, } @inproceedings{CTT100858450, author = {Naeko Iwai and Yoko Nagumo and Sotaro Takahashi and Fumitaka Kudo and Tadashi Eguchi and Takeo Usui}, title = {Hitachimycinによる出芽酵母細胞内pHホメオスタシス障害}, booktitle = {}, year = 2021, } @inproceedings{CTT100858445, author = {Kazuho Okada and Akane Hirayama and Fumitaka Kudo and Tadashi Eguchi}, title = {抗腫瘍抗生物質パクタマイシン生合成における脱水素酵素PctPの基質特異性}, booktitle = {}, year = 2021, } @inproceedings{CTT100858443, author = {Taichi Hirayama and Fumitaka Kudo and Tadashi Eguchi}, title = {アナモックス菌の細胞膜成分ラダラン脂質の推定生合成中間体の合成研究}, booktitle = {}, year = 2021, } @inproceedings{CTT100858442, author = {Mai Mutoh and Fumitaka Kudo and Tadashi Eguchi}, title = {ジテルペングリコシド抗生物質ソルダリンの麹菌異種発現系を用いた生合成解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100858441, author = {Shusuke Sato and Fumitaka Kudo and Tadashi Eguchi}, title = {バクテリオホパンポリオール生合成において炭素-炭素結合形成反応を触媒するラジカルSAM酵素HpnHの機能解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100845833, author = {Akimasa Miyanaga and Yukinobu Kitayama and Fumitaka Kudo and Tadashi Eguchi}, title = {カナマイシン生合成酵素KanD2とKanJの結晶構造解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100845832, author = {Taichi Chisuga and Akimasa Miyanaga and Shohei Kurihara and 安達成彦 and 川崎政人 and 守屋俊夫 and 千田俊哉 and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ヒタチマイシン生合成におけるアデニル化酵素とキャリアタンパク質間相互認識機構}, booktitle = {}, year = 2021, } @inproceedings{CTT100845830, author = {Daiki Nagayama and Yuichiro Nakazawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ヒタチマイシン生合成におけるポストPKS修飾酵素の機能解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100808979, author = {石川文洋 and Akimasa Miyanaga and 北山陽菜乃 and Fumitaka Kudo and Tadashi Eguchi and 田邉 元三}, title = {アデニル化酵素のエンジニアリングによる基質許容性の拡張および構造的基盤}, booktitle = {}, year = 2019, } @inproceedings{CTT100808982, author = {Akimasa Miyanaga and Taichi Chisuga and Daisuke Kawasaki and Fumitaka Kudo and Tadashi Eguchi}, title = {クレミマイシン生合成における3-アミノノナン酸ユニット構築に関わる酵素の構造機能解析}, booktitle = {}, year = 2019, } @inproceedings{CTT100808981, author = {石川文洋 and Akimasa Miyanaga and 北山陽菜乃 and Fumitaka Kudo and Tadashi Eguchi and 田邉 元三}, title = {アデニル化酵素の基質特異性の拡張および構造的基盤}, booktitle = {}, year = 2019, } @inproceedings{CTT100808980, author = {Fumihiro Ishikawa and Akimasa Miyanaga and Hinano Kitayama and Fumitaka Kudo and Tadashi Eguchi and Genzoh Tanabe}, title = {Reprogramming aryl acid adenylation domains for non-native building blocks}, booktitle = {}, year = 2019, } @inproceedings{CTT100808985, author = {Sotaro Takahashi and Yuichiro Nakazawa and Koichi Kawamura and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Engineering of hitachimycin biosynthesis}, booktitle = {}, year = 2019, } @inproceedings{CTT100808983, author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthetic studies on 3-aminononanoic acid starter unit of cremimycin}, booktitle = {}, year = 2019, } @inproceedings{CTT100808984, author = {Kosuke Kishikawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Engineering of macrocyclic polyketides biosynthesis in Streptomyces graminofaciens}, booktitle = {}, year = 2019, } @inproceedings{CTT100808978, author = {石川文洋 and Akimasa Miyanaga and 北山陽菜乃 and Fumitaka Kudo and Tadashi Eguchi and 田邉元三}, title = {アデニル化酵素の基質特異性の拡張および構造的基盤}, booktitle = {}, year = 2019, } @inproceedings{CTT100792471, author = {Hiroaki Kishikawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {18員環マクロライド抗生物質Virustomycin Aの生合成遺伝子クラスター}, booktitle = {}, year = 2019, } @inproceedings{CTT100806722, author = {Shusuke Sato and Fumitaka Kudo and Tomohisa Kuzuyama and Tadashi Eguchi}, title = {Radical SAM C-Methylation in Fosfomycin Biosynthesis}, booktitle = {}, year = 2019, } @inproceedings{CTT100792791, author = {Shuusuke Satou and Akimasa Miyanaga and 葛山智久 and Fumitaka Kudo and Tadashi Eguchi}, title = {ホスホマイシン生合成における新規加水分解酵素FomDの機能解析}, booktitle = {}, year = 2019, } @inproceedings{CTT100792474, author = {Jolanta Cieslak and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Functional and structural analysis of unique adenylation enzyme IdnL7 involved in biosynthesis of macrolactam antibiotic incednine}, booktitle = {}, year = 2019, } @inproceedings{CTT100792473, author = {Ena Goto and Risako Ouchi and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {ジソラゾール生合成におけるアシル基転移酵素とアシルキャリアプロテイン間の相互作用解析}, booktitle = {}, year = 2019, } @inproceedings{CTT100792472, author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質クレミマイシン生合成におけるsplit DHドメインの機能解析}, booktitle = {}, year = 2019, } @inproceedings{CTT100792470, author = {Yukinobu Kitayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {カナマイシン生合成における脱水素酵素KanD2の基質認識機構}, booktitle = {}, year = 2019, } @inproceedings{CTT100779586, author = {Fumitaka Kudo and Akane Hirayama and Jiahao Zhang and Akimasa Miyanaga and Tadashi Eguchi}, title = {抗腫瘍抗生物質パクタマイシンの生合成研究}, booktitle = {}, year = 2018, } @inproceedings{CTT100780279, author = {Shusuke Sato and Fumitaka Kudo and Tomohisa Kuzuyama and Tadashi Eguchi}, title = {C-Methylation mechanism in fosfomycin biosynthesis}, booktitle = {}, year = 2018, } @inproceedings{CTT100779580, author = {Fumitaka Kudo and Akimasa Miyanaga and Ryuichi Takayanagi and Takashi Furuya and Atsushi Motegi and Tadashi Eguchi}, title = {Study on a dual functional cytochrome P450 in the biosynthesis of macrolide antibiotic FD-891}, booktitle = {}, year = 2018, } @inproceedings{CTT100779577, author = {Ena Goto and Risako Ouchi and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Cross-linking reaction to investigate protein-protein interaction in polyketide synthases}, booktitle = {}, year = 2018, } @inproceedings{CTT100779578, author = {Kosuke Kishikawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthesis of two macrolides produced by Streptomyces graminofaciens}, booktitle = {}, year = 2018, } @inproceedings{CTT100780129, author = {Fumitaka Kudo and Shuusuke Satou and TADASHI EGUCHI}, title = {Radical SAM enzymes in natural products biosynthesis}, booktitle = {}, year = 2018, } @inproceedings{CTT100779575, author = {Daisuke Kawasaki and Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthesis of 3-aminofatty acid starter units of macrolactam antibiotics}, booktitle = {}, year = 2018, } @inproceedings{CTT100779569, author = {Kaito Yamaguchi and Takeshi Tunoda and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {ヌクレオシド系抗生物質アリステロマイシンの生合成における炭素五員環形成の立体}, booktitle = {}, year = 2018, } @inproceedings{CTT100779572, author = {Yuichiro Nakazawa and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ヒタチマイシンの生合成におけるATP依存リガーゼHitBの基質特異性}, booktitle = {}, year = 2018, } @inproceedings{CTT100779571, author = {Risako Ouchi and 石川文洋 and Ena Goto and 木村真希 and Akimasa Miyanaga and 田邉元三 and Fumitaka Kudo and Tadashi Eguchi}, title = {ポリケチド生合成におけるアシル基転移酵素とアシルキャリアタンパク質のクロスリンク反応の検討}, booktitle = {}, year = 2018, } @inproceedings{CTT100779570, author = {Takaoki Kitayama and Akane Hirayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {カナマイシン生合成におけるカノサミン部位の構築機構}, booktitle = {}, year = 2018, } @inproceedings{CTT100780131, author = {Shusuke Sato and Seung-Young Kim and Tomohisa Kuzuyama and Fumitaka Kudo and Tadashi Egchi}, title = {C-Methylation in the Fosfomycin Biosynthesis}, booktitle = {}, year = 2017, } @inproceedings{CTT100780283, author = {Shuusuke Satou and Fumitaka Kudo and Tadashi Eguchi and 葛山智久}, title = {ホスホマイシン生合成におけるラジカルS-アデノシル-L-メチオニンC-メチル化酵素の機能解析}, booktitle = {}, year = 2017, } @inproceedings{CTT100780285, author = {Akane Hirayama and Fumitaka Kudo and Tadashi Eguchi}, title = {抗腫瘍抗生物質パクタマイシンの生合成におけるアミノ基導入機構}, booktitle = {}, year = 2017, } @inproceedings{CTT100780140, author = {Fumitaka Kudo and Takahiro Tokumitsu and Tadashi Eguchi}, title = {Functional analysis of radical SAM enzyme AprD4 and reductase AprD3 in the C3′-deoxygenation in apramycin biosynthesis}, booktitle = {}, year = 2017, } @inproceedings{CTT100779562, author = {Ryuichi Takayanagi and Takashi Furuya and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi and 川又綾乃 and 岩渕好治 and 叶直樹}, title = {マクロライド系抗生物質FD-891の生合成におけるシトクロムP450酸化酵素GfsFの基質特異性}, booktitle = {}, year = 2017, } @inproceedings{CTT100779561, author = {Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Ⅲ型チオエステラーゼ SAV606の構造機能解析}, booktitle = {}, year = 2017, } @inproceedings{CTT100779611, author = {Jolanta Cieslak and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Structural analysis of hydrophobic β-amino acid adenylation enzymes CmiS6 and IdnL1}, booktitle = {}, year = 2016, } @inproceedings{CTT100779612, author = {Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質クレミマイシンの生合成における開始基質3-アミノノナン酸の構築機構-FAD依存酸化酵素CmiS2の構造機能解析}, booktitle = {}, year = 2016, } @inproceedings{CTT100779610, author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi}, title = {Biosynthesis of Macrolactam Antibiotics in Actinomycetes}, booktitle = {}, year = 2016, } @inproceedings{CTT100779606, author = {Fumitaka Kudo and Takeshi Tunoda and Akimasa Miyanaga and Makoto Takashima and Tadashi Eguchi}, title = {ヌクレオシド系抗生物質アリステロマイシンの生合成遺伝子のゲノムマイニング}, booktitle = {}, year = 2016, } @inproceedings{CTT100779605, author = {Taichi Chisuga and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {III 型チオエステラーゼの構造機構解析}, booktitle = {}, year = 2016, } @inproceedings{CTT100749125, author = {Akimasa Miyanaga and yuki hayakawa and Mario Numakura and 橋本絢子 and 新家一男 and Fumitaka Kudo and Tadashi Eguchi}, title = {Fluvirucin B2生合成遺伝子クラスターの同定と機能解析}, booktitle = {}, year = 2016, } @inproceedings{CTT100779600, author = {Taishi Ando and Koichi Kawamura and Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi}, title = {ポリケチド抗生物質ヒタチマイシン生合成における PKS 後修飾機構解明に向けた遺伝子破壊実験}, booktitle = {}, year = 2016, } @inproceedings{CTT100779613, author = {Akane Hirayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {Characterization of PLP-dependent 3-aminobenzoate synthase PctV in pactamycin biosynthesis}, booktitle = {}, year = 2015, } @inproceedings{CTT100749118, author = {Akimasa Miyanaga and Jolanta Cieślak and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi}, title = {Functional and structural of β-amino acid-activating adenylation enzymes in macrolactam biosynthesis}, booktitle = {}, year = 2015, } @inproceedings{CTT100779615, author = {Kouta Nishino and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {生合成遺伝子破壊株を利用したヒタチマイシン類縁体生産の試み}, booktitle = {}, year = 2015, } @inproceedings{CTT100779616, author = {Shohei Iwasawa and Akimasa Miyanaga and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ビセニスタチン生合成に関わるアシル基転移酵素VinKの基質認識機構解析}, booktitle = {}, year = 2015, } @inproceedings{CTT100749120, author = {Akimasa Miyanaga and Yuji Shinohara and Shohei Iwasawa and Jolanta Cieślak and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ビセニスタチン生合成酵素の構造機能解析に基づくβ-アミノ酸スターター部位構築機構の解明}, booktitle = {}, year = 2015, } @inproceedings{CTT100779622, author = {Ayaka Mori and mai koide and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {糖質から炭素六員環化合物への酵素的変換}, booktitle = {}, year = 2015, } @inproceedings{CTT100779627, author = {Takeshi Tunoda and Makoto Takashima and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {ヌクレオシド系抗生物質アリステロマイシン生合成に関わるOrf2の機能解析}, booktitle = {}, year = 2015, } @inproceedings{CTT100749123, author = {Akimasa Miyanaga and Takashi Furuya and Fumitaka Kudo and Tadashi Eguchi}, title = {FD-891生合成に関わるシトクロムP450酸化酵素GfsFの結晶構造解析}, booktitle = {}, year = 2015, } @inproceedings{CTT100779626, author = {yuki hayakawa and Koichi Kawamura and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {非天然型基質投与によるヒタチマイシン類縁体生産}, booktitle = {}, year = 2015, } @inproceedings{CTT100779625, author = {Koichi Kawamura and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {ポリケチド抗生物質ヒタチマイシンの生合成遺伝子の機能解析}, booktitle = {}, year = 2015, } @inproceedings{CTT100779624, author = {Takashi Furuya and Koichi Kawamura and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロライド系抗生物質FD-891生合成におけるポストPKS修飾酵素の機能解析}, booktitle = {}, year = 2015, } @inproceedings{CTT100779623, author = {Akane Hirayama and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {パクタマイシン生合成における3-アミノ安息香酸合成酵素の反応}, booktitle = {}, year = 2015, } @inproceedings{CTT100749127, author = {Akimasa Miyanaga and Yuji Shinohara and Fumitaka Kudo and Tadashi Eguchi}, title = {ビセニスタチン生合成におけるATP依存性リガーゼVinNの結晶構造解析}, booktitle = {}, year = 2014, } @inproceedings{CTT100779630, author = {Asuka Uchino and Mario Numakura and Akimasa Miyanaga and Tadashi Eguchi and Fumitaka Kudo}, title = {マクロラクタム抗生物質ヒタチマイシンのスターター部位構築に関わる酵素の機能解析}, booktitle = {}, year = 2014, } @inproceedings{CTT100779634, author = {Yuji Shinohara and Akimasa Miyanaga and Fumitaka Kudo and Tadashi Eguchi}, title = {マクロラクタム抗生物質ビセニスタチン生合成に関わるペプチダーゼVinJのX線結晶構造解析}, booktitle = {}, year = 2013, } @misc{CTT100678396, author = {Fumitaka Kudo and Akimasa Miyanaga and Tadashi Eguchi}, title = {β-アミノ酸含有マクロラクタム抗生物質の生合成}, year = 2014, } @misc{CTT100574493, author = {Fumitaka Kudo and Tadashi Eguchi}, title = {Biosynthetic Enzymes for the Aminoglycosides Butirosin and Neomycin}, year = 2009, } @misc{CTT100549397, author = {Eriko Nango and TADASHI EGUCHI}, title = {糖質環化酵素の構造と機能の解明 −バイオマスから化学工業資源へ−}, year = 2008, } @misc{CTT100541862, author = {Fumitaka Kudo and TADASHI EGUCHI}, title = {天然有機化合物の生合成に学ぶ アミノグリコシド抗生物質生合成研究の進歩}, year = 2006, } @misc{CTT100594192, author = {TADASHI EGUCHI}, title = {ビタミンD3の活性代謝物並びに関連化合物の立体化学及び生理活性に関する研究}, year = 1990, } @misc{CTT100674897, author = {TADASHI EGUCHI and Fumitaka Kudo}, title = {2-デオキシ-scyllo-イノソースの調製法 }, howpublished = {PublishedPatent}, year = 2014, month = {}, note = {特願2012-211752(2012/09/26), 特開2014-064513(2014/04/17)} } @misc{CTT100630147, author = {TADASHI EGUCHI}, title = {エンド-β-1, 4-グルカナーゼ、酵素組成物、ポリヌクレオチド、ポリヌクレオチド構造体、組換プラスミド、形質転換微生物、及びエンド-β-1, 4-グルカナーゼの製造方法}, howpublished = {PublishedPatent}, year = 2011, month = {}, note = {特願2009-267144(2009/11/25), 特開2011-109937(2011/06/09)} } @misc{CTT100577199, author = {TADASHI EGUCHI}, title = {ホモイソクエン酸脱水素酵素の阻害剤}, howpublished = {PublishedPatent}, year = 2009, month = {}, note = {特願2007-184589(2007/07/13), 特開2009-019021(2009/01/29)} } @misc{CTT100572827, author = {KATSUMI KAKINUMA and Fumitaka Kudo and TADASHI EGUCHI}, title = {ラクタム及びラクトン合成酵素}, howpublished = {PublishedPatent}, year = 2006, month = {}, note = {特願2005-019886(2005/01/27), 特開2006-204169(2006/08/10)} } @phdthesis{CTT100594192, author = {TADASHI EGUCHI}, title = {ビタミンD3の活性代謝物並びに関連化合物の立体化学及び生理活性に関する研究}, school = {Tokyo Institute of Technology}, year = 1990, }