@book{CTT100712750, author = {駒田雅之}, title = {クッシング病の原因遺伝子と発症機構}, publisher = {}, year = 2016, } @book{CTT100712771, author = {駒田雅之}, title = {増殖因子受容体の分解制御と制癌}, publisher = {}, year = 2016, } @book{CTT100712751, author = {駒田雅之}, title = {脱ユビキチン化酵素USP8変異とCushing病}, publisher = {}, year = 2015, } @book{CTT100712772, author = {駒田雅之}, title = {増殖因子受容体の分解制御と制癌}, publisher = {}, year = 2009, } @book{CTT100712773, author = {駒田雅之}, title = {アミノ酸とヌクレオチドの代謝}, publisher = {}, year = 2008, } @book{CTT100712774, author = {駒田雅之}, title = {輸送タンパク質は体内の宅配便}, publisher = {}, year = 2007, } @book{CTT100532001, author = {駒田雅之 and 水野英美}, title = {エンドソームにおけるメンブレントラフィックの脱ユビキチン化による調節}, publisher = {細胞工学}, year = 2006, } @book{CTT100540163, author = {駒田雅之}, title = {軸索起始部とランビエ絞輪へのNaチャネル局在化機構}, publisher = {生体の科学}, year = 2005, } @book{CTT100387617, author = {駒田雅之}, title = {受容体チロシンキナーゼのユビキチン化による分解機構}, publisher = {現代医療}, year = 2004, } @book{CTT100540161, author = {駒田雅之}, title = {ホスファチジルイノシトール3-リン酸とエンドソームにおける膜輸送}, publisher = {ファルマシア}, year = 2004, } @book{CTT100438583, author = {駒田雅之}, title = {FYVEフィンガータンパク質Hrsのマウス発生における役割}, publisher = {実験医学}, year = 1999, } @book{CTT100438595, author = {Masayuki Komada}, title = {Gene expression and regulation of HGF-SF}, publisher = {Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and the C-Met Receptor}, year = 1993, } @article{CTT100898144, author = {Yomogita H and Ito H and Hashimoto K and Kudo A and Fukushima T and Endo T and Hirate Y and Akimoto Y and Komada M and Kanai Y and Miyasaka N and Kanai-Azuma M}, title = {A possible function of Nik-related kinase in the labyrinth layer of delayed delivery mouse placentas}, journal = {J Reprod Dev Mol}, year = 2022, } @article{CTT100874480, author = {Beni Lestari and Satomi Naito and Akinori Endo and Hidenori Nishihara and Akira Kato and Erika Watanabe and Kimitoshi Denda and Masayuki Komada and Toshiaki Fukushima}, title = {Placental Mammals Acquired Functional Sequences in NRK for Regulating the CK2–PTEN–AKT Pathway and Placental Cell Proliferation}, journal = {Molecular Biology and Evolution}, year = 2022, } @article{CTT100875112, author = {Keijun Kakihara and Kengo Asamizu and Kei Moritsugu and Masahide Kubo and Tetsuya Kitaguchi and Akinori Endo and Akinori Kidera and Mitsunori Ikeguchi and Akira Kato and Masayuki Komada and Toshiaki Fukushima.}, title = {Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.}, journal = {Commun Biol}, year = 2021, } @article{CTT100853325, author = {Mattioni A and Boldt K and Auciello G and Rappoport JZ and Ueffing M and Castagnoli L and Cesareni G and Santonico E. and Anna Mattioni and Karsten Boldt and Giulio Auciello and Masayuki Komada and Joshua Z Rappoport and Marius Ueffing and Luisa Castagnoli and Gianni Cesareni and Elena Santonico}, title = {Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family.}, journal = {The FEBS Journal}, year = 2020, } @article{CTT100837022, author = {Satomi Naito and Toshiaki Fukushima and Akinori Endo and Kimitoshi Denda and Masayuki Komada}, title = {Nik-related kinase is targeted for proteasomal degradation by the chaperone-dependent ubiquitin ligase CHIP}, journal = {FEBS Letters}, year = 2020, } @article{CTT100839127, author = {KIMITOSHI DENDA and Kanako Ida and Masataka Tanno and Kanako Nakao-Wakabayashi and Masayuki Komada and nobuhiro hayashi}, title = {Proteomic analysis of Nrk gene-disrupted placental tissue cells explains physiological significance of NRK}, journal = {BMC research notes}, year = 2019, } @article{CTT100853334, author = {Kimitoshi Denda and Kanako Ida and Masataka Tanno Kanako Nakao-Wakabayashi and Masayuki Komada and Nobuhiro Hayashi}, title = {Proteomic analysis of Nrk gene-disrupted placental tissue cells explains physiological significance of NRK}, journal = {BMC research notes}, year = 2019, } @article{CTT100853336, author = {Keishi Fukuura and Yasumichi Inoue and Chiharu Miyajima and Shin Watanabe and Muneshige Tokugawa and Daisuke Morishita and Nobumichi Ohoka and Masayuki Komada and Hidetoshi Hayashi}, title = {The ubiquitin-specific protease USP17 prevents cellular senescence by stabilizing the methyltransferase SET8 and transcriptionally repressing p21}, journal = {The journal of biological chemistry}, year = 2019, } @article{CTT100813373, author = {WH. Chan and M. Komada and T. Fukushima and EM. Southard-Smith and CR. Anderson. MJ. Wakefield}, title = {RNA-seq of Isolated Chromaffin Cells Highlights the Role of Sex-Linked and Imprinted Genes in Adrenal Medulla Development}, journal = {Scientific Reports}, year = 2019, } @article{CTT100853340, author = {Ryohei Sakai and Ryosuke Fukuda and Shin Unida and Misaki Aki and Yuji Ono and Akinori Endo and Satoshi Kusumi and Daisuke Koga and Toshiaki Fukushima and Masayuki Komada and Tsukasa Okiyoneda}, title = {The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors}, journal = {Journal of cell science}, year = 2019, } @article{CTT100853339, author = {Ryohei Sakai and Ryosuke Fukuda and Shin Unida and Misaki Aki and Yuji Ono and Akinori Endo and Satoshi Kusumi and Daisuke Koga and Toshiaki Fukushima and Masayuki Komada and Tsukasa Okiyoneda}, title = {The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors}, journal = {Journal of cell science}, year = 2019, } @article{CTT100813374, author = {H. Furuta and H. Yoshihara and T. Fukushima and Y. Yoneyama and A. Ito and C. Worrall and A. Girnita and L. Girnita and M. Yoshida and T. Asano and M. Komada and N. Kataoka and K. Chida and F. Hakuno and SI. Takahashi}, title = {IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line}, journal = {Oncotarget}, year = 2018, } @article{CTT100853343, author = {Julia Saifetiarova and Martin Paukert and Masayuki Komada and Manzoor A Bhat}, title = {Reorganization of Destabilized Nodes of Ranvier in β IV Spectrin Mutants Uncovers Critical Timelines for Nodal Restoration and Prevention of Motor Paresis}, journal = {The Journal of neuroscience}, year = 2018, } @article{CTT100774007, author = {Kohei Kawaguchi and Kazune Uo and Toshiaki Tanaka and Masayuki Komada}, title = {Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25}, journal = {Scientific Reports}, year = 2017, } @article{CTT100712713, author = {Masayuki Komada}, title = {The Ankrd13 Family of Ubiquitin-interacting Motif-bearing Proteins Regulates Valosin-containing Protein/p97 Protein-mediated Lysosomal Trafficking of Caveolin 1}, journal = {J. Biol. Chem.}, year = 2016, } @article{CTT100712710, author = {Masayuki Komada}, title = {The USP8 mutational status may predict drug susceptibility in corticotroph adenomas of Cushing's disease}, journal = {Eur. J. Endocrinol.}, year = 2016, } @article{CTT100712711, author = {Masayuki Komada}, title = {The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease}, journal = {J. Clin. Endocrinol. Metab.}, year = 2015, } @article{CTT100712709, author = {Masayuki Komada}, title = {The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc}, journal = {Proc. Natl. Acad. Sci. USA}, year = 2015, } @article{CTT100712712, author = {Masayuki Komada}, title = {Mutations in the deubiquitinase gene USP8 cause Cushing's disease}, journal = {Nat. Genet.}, year = 2015, } @article{CTT100712708, author = {Masayuki Komada}, title = {In vivo assembly of the axon initial segment in motor neurons}, journal = {Brain Struct. Funct.}, year = 2014, } @article{CTT100684764, author = {Hidetaka Tanno and Takeshi Shigematsu and Shuhei Nishikawa and Akira Hayakawa and Kimitoshi Denda and Toshiaki Tanaka and Masayuki Komada}, title = {Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37}, journal = {Journal of Biological Chemistry}, year = 2014, } @article{CTT100712707, author = {Masayuki Komada}, title = {Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS}, journal = {Histochem. Cell Biol.}, year = 2013, } @article{CTT100684763, author = {X.Li and Y.Bian and Y.Takizawa and T.Hashiomoto and N.Kitamura and T.Ikoma and J.Tanaka and Y.Inagaki and M.Komada and T.Tanaka}, title = {ERK-dependent downregulation of Skp2 reduces Myc activity with HGF, leading to inhibition of cell proliferation through a decrease in Id1 expression.}, journal = {Molecular Cancer Research}, year = 2013, } @article{CTT100712706, author = {Masayuki Komada}, title = {The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane}, journal = {Mol. Biol. Cell}, year = 2012, } @article{CTT100712705, author = {Masayuki Komada}, title = {Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves}, journal = {Mol. Cell. Biol.}, year = 2012, } @article{CTT100712704, author = {Masayuki Komada}, title = {Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor}, journal = {J. Biol. Chem.}, year = 2011, } @article{CTT100712703, author = {Masayuki Komada}, title = {Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor}, journal = {Nat. Commun.}, year = 2011, } @article{CTT100712700, author = {Masayuki Komada}, title = {Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis}, journal = {J. Neuropathol. Exp. Neurol.}, year = 2010, } @article{CTT100712702, author = {Masayuki Komada}, title = {Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt}, journal = {EMBO J.}, year = 2010, } @article{CTT100712701, author = {Masayuki Komada}, title = {Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay}, journal = {Am. J. Hum. Genet.}, year = 2010, } @article{CTT100712699, author = {Masayuki Komada}, title = {Involvement of a membrane skeletal protein, 4.1G, for Sertoli/germ cell interaction}, journal = {Reproduction}, year = 2010, } @article{CTT100712697, author = {Masayuki Komada}, title = {Nucleophosmin/B23 regulates ubiquitin dynamics in nucleoli by recruiting deubiquitylating enzyme USP36}, journal = {J. Biol. Chem.}, year = 2009, } @article{CTT100712696, author = {Masayuki Komada}, title = {Dispensable role of protein 4.1B/DAL-1 in rodent adrenal medulla regarding generation of pheochromocytoma and plasmalemmal localization of TSLC1}, journal = {}, year = 2009, } @article{CTT100712698, author = {Masayuki Komada}, title = {Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36}, journal = {J. Cell Sci.}, year = 2009, } @article{CTT100712694, author = {Masayuki Komada}, title = {Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains}, journal = {Nature}, year = 2008, } @article{CTT100712692, author = {Masayuki Komada}, title = {Sodium channel cluster, betaIV-spectrin and ankyrinG positive "hot spots" on dendritic segments of parvalbumin-containing neurons and some other neurons in the mouse and rat main olfactory bulbs}, journal = {Neurosci. Res.}, year = 2008, } @article{CTT100712693, author = {Masayuki Komada}, title = {Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2}, journal = {Biochem. J.}, year = 2008, } @article{CTT100712695, author = {Masayuki Komada}, title = {Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis}, journal = {J. Cell Sci.}, year = 2008, } @article{CTT100712689, author = {Masayuki Komada}, title = {Interaction of membrane skeletal protein, protein 4.1B and p55, and sodium bicarbonate cotransporter 1 in mouse renal S1-S2 proximal tubules}, journal = {J. Histochem. Cytochem.}, year = 2007, } @article{CTT100712691, author = {Masayuki Komada}, title = {14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase}, journal = {Exp. Cell Res.}, year = 2007, } @article{CTT100712690, author = {Masayuki Komada}, title = {Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein}, journal = {J. Biol. Chem.}, year = 2007, } @article{CTT100532004, author = {Mizuno, E. and Kobayashi, K. and Yamamoto, A. and Kitamura, N. and Komada, M.}, title = {A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes}, journal = {Traffic}, year = 2006, } @article{CTT100532006, author = {Uemoto, Y. and Suzuki, S. and Terada, N. and Ohno, N. and Ohno, S. and Yamanaka, S. and Komada, M.}, title = {Specific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of Ranvier.}, journal = {J. Biol. Chem.}, year = 2006, } @article{CTT100532007, author = {Nishimura, K. and Akiyama, H. and Komada, M. and Kamiguchi, H.}, title = {betaIV-spectrin forms a diffusion barrier against L1CAM at the axon initial segment.}, journal = {Mol. Cell. Neurosci.}, year = 2006, } @article{CTT100532002, author = {Nakamura, N. and Tanaka, N. and Kitamura, N. and Komada, M.}, title = {Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.}, journal = {Genes Cells}, year = 2006, } @article{CTT100532003, author = {Ohno, N. and Terada, N. and Yamakawa, H. and Komada, M. and Ohara, O. and Trapp, B. D. and Ohno, S.}, title = {Expression of protein 4.1G in Schwann cells of the peripheral nervous system}, journal = {J. Neurosci. Res.}, year = 2006, } @article{CTT100532005, author = {Yamasaki, A. and Tani, K. and Yamamoto, A. and Kitamura, N. and Komada, M.}, title = {The Ca2+-binding protein ALG-2 is recruited to ER exit sites by Sec31A and stabilizes the localization of Sec31A}, journal = {Mol. Biol. Cell}, year = 2006, } @article{CTT100541867, author = {Mizuno, E. and Iura, T. and Mukai, A. and Yoshimori, T. and Kitamura, N. and Komada, M.}, title = {Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes.}, journal = {Mol. Biol. Cell}, year = 2005, } @article{CTT100540162, author = {Komada, M. and Kitamura, N}, title = {The Hrs/STAM complex in the downregulation of receptor tyrosine kinases.}, journal = {J. Biochem.}, year = 2005, } @article{CTT100540160, author = {Morino, C. and Kato, M. and Yamamoto, A. and Mizuno, E. and Hayakawa, A. and Komada, M. and Kitamura, N.}, title = {A role for Hrs in endosomal sorting of ligand-stimulated and unstimulated epidermal growth factor receptor.}, journal = {Exp. Cell Res.}, year = 2004, } @article{CTT100540159, author = {Mizuno, E. and Kawahata, K. and Okamoto, A. and Kitamura, N. and Komada, M.}, title = {Association with Hrs is required for the early endosomal localization, stability, and function of STAM}, journal = {J. Biochem.}, year = 2004, } @article{CTT100538768, author = {Mizuno, E. and Kawahata, K. and Kato, M. and Kitamura, N. and Komada, M.}, title = {STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif.}, journal = {Mol. Biol. Cell}, year = 2003, } @article{CTT100538767, author = {Kunzmann, S. and Wohlfahrt, J.G. and Itoh, S. and Asao, H. and Komada, M. and Akdis, C.A. and Blaser, K. and Schmidt-Weber, C.B.}, title = {SARA and Hrs attenuate susceptibility to TGF-beta1-mediated T cell suppression.}, journal = {FASEB J.}, year = 2003, } @article{CTT100538273, author = {Komada, M. and Soriano, P}, title = {betaIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier.}, journal = {J. Cell Biol.}, year = 2002, } @article{CTT100538584, author = {Sun and C.-X. and Haipek, C. and Scoles, D.R. and Pulst, S.M. and Giovannini, M. and Komada, M. and Gutmann, D.H.}, title = {Functional analysis of the relationship between the neurofibromatosis 2 tumor suppressor and its binding partner, Hrs (hepatocyte growth factor-regulated tyrosine kinase substrate).}, journal = {Hum. Mol. Genet.}, year = 2002, } @article{CTT100537858, author = {Komada, M. and Kitamura, N.}, title = {Hrs and Hbp: possible regulators of endocytosis and exocytosis}, journal = {Biochem. Biophys. Res. Commun.}, year = 2001, } @article{CTT100537482, author = {Komada, M. and McLean, D.J. and Griswold, M.D. and Russell, L.D. and Soriano, P.}, title = {E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis}, journal = {Genes Dev.}, year = 2000, } @article{CTT100537483, author = {Komada, M. and Soriano, P.}, title = {Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis}, journal = {Genes Dev.}, year = 1999, } @article{CTT100537484, author = {Masayuki Komada}, title = {Human Hrs, a tyrosine kinase substrate in growth factor-stimulated cells: cDNA cloning and mapping of the gene to chromosome 17}, journal = {Gene}, year = 1998, } @article{CTT100537485, author = {Komada, M. and Masaki, R. and Yamamoto, A. and Kitamura, N.}, title = {Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes}, journal = {J. Biol. Chem.}, year = 1997, } @article{CTT100537486, author = {Masayuki Komada}, title = {Vascular endothelial growth factor expression in choroidal neovascularization in rats}, journal = {Graefe's Arch. Clin. Exp. Ophthalmol.}, year = 1997, } @article{CTT100537487, author = {Komada, M. and Kitamura, N}, title = {Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain}, journal = {Mol. Cell. Biol.}, year = 1995, } @article{CTT100537488, author = {Komada, M. and Kitamura, N.}, title = {Regulatory role of major tyrosine autophosphorylation site of kinase domain of c-Met receptor (scatter factor/hepatocyte growth factor receptor)}, journal = {J. Biol. Chem.}, year = 1994, } @article{CTT100537491, author = {Komada, M. and Hatsuzawa, K. and Shibamoto, S. and Ito, F. and Nakayama, K. and Kitamura, N.}, title = {Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin}, journal = {FEBS Lett.}, year = 1993, } @article{CTT100537489, author = {Masayuki Komada}, title = {Evidence for involvement of furin in cleavage and activation of diphtheria toxin}, journal = {J. Biol. Chem.}, year = 1993, } @article{CTT100537490, author = {Komada, M. and Kitamura, N.}, title = {The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor}, journal = {Oncogene}, year = 1993, } @article{CTT100537493, author = {Komada, M. and Miyazawa, K. and Ishii, T. and Kitamura, N.}, title = {Characterization of hepatocyte-growth-factor receptors on Meth A cells}, journal = {Eur. J. Biochem.}, year = 1992, } @article{CTT100537494, author = {Masayuki Komada}, title = {Detection of three distinct phospholipases A2 in cultured mast cells}, journal = {J. Biochem.}, year = 1992, } @article{CTT100537492, author = {Masayuki Komada}, title = {Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains}, journal = {Biochemistry}, year = 1992, } @article{CTT100537495, author = {Komada, M. and Kudo, M. and Inoue, K.}, title = {Structure of gene coding for rat group II phospholipase A2}, journal = {Biochem. Biophy. Res. Commun.}, year = 1990, } @article{CTT100537496, author = {Komada, M. and Kudo, I. and Mizushima, H. and Kitamura, N. and Inoue, K.}, title = {Structure of cDNA coding for rat platelet phospholipase A2}, journal = {J. Biochem.}, year = 1989, } @inproceedings{CTT100898133, author = {Keijun Kakihara and Masayuki Komada and Toshiaki Fukushima}, title = {Caspase-dependent STAMBPL1 cleavage promotes cell death through its C-terminal fragment with hyperactive deubiquitinating activity}, booktitle = {}, year = 2023, } @inproceedings{CTT100898129, author = {Keijun Kakihara and Masayuki Komada and Toshiaki Fukushima}, title = {Cis-activity regulation of USP8 and STAMBPL1, two endosomal deubiquitinating enzymes, and role of dysregulation in disease onset}, booktitle = {}, year = 2022, } @inproceedings{CTT100898131, author = {Gai Ando and Keijun Kakihara and Masayuki Komada and Toshiaki Fukushima}, title = {Molecular mechanisms underlying the over-activation of USP8 and USP48 by Cushing’s disease-associated mutations}, booktitle = {}, year = 2022, } @inproceedings{CTT100898138, author = {福嶋 俊明 and 柿原 慧遵 and 浅水 謙吾 and 森次 圭 and 北口 哲也 and 駒田 雅之}, title = {クッシング病を引き起こすUSP8の過剰活性化機構}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100898135, author = {Marsya Yonna Nurrachma and Beni Lestari and 駒田 雅之 and 福嶋 俊明}, title = {Ubiquitination-mediated activation of AKT and its cancer-associated mutants}, booktitle = {}, year = 2022, } @inproceedings{CTT100898134, author = {西岡 柚香 and 柿原 慧遵 and 遠藤 彬則 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン化酵素USP8によるVAMP8の制御とその細胞質分裂における意義の解明}, booktitle = {}, year = 2022, } @inproceedings{CTT100898141, author = {Keijun Kakihara and Kei Moritsugu and Tetsuya Kitaguchi and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {Autoinhibition of USP8 by WW-like domain and the dysregulation in Cushing’s disease}, booktitle = {EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”}, year = 2022, } @inproceedings{CTT100898140, author = {福嶋 俊明 and 柿原 慧遵 and 駒田 雅之}, title = {脱ユビキチン化酵素USP8の遺伝子変異を介したクッシング病の発症メカニズム}, booktitle = {}, year = 2022, } @inproceedings{CTT100875549, author = {蓬田裕 and 高峰愛幸 and 伊藤日加瑠 and 平手良和 and 福嶋俊明 and 駒田雅之 and 金井克晃 and 宮坂尚幸 and 金井正美}, title = {マウス、ヒト胎盤におけるNrk下流遺伝子群と分娩遅延の関連について}, booktitle = {}, year = 2021, } @inproceedings{CTT100875548, author = {BENI Lestari and 内藤 聡美 and 遠藤 彬則 and 西原 秀典 and 加藤 明 and 渡邊 恵理香 and 傳田 公紀 and 駒田 雅之 and 福嶋 俊明}, title = {Comparative Phylogenetic Analysis and Molecular Characterization Reveal Eutherian-Specific Role of NRK in Regulating Placenta Development}, booktitle = {}, year = 2021, } @inproceedings{CTT100875547, author = {氷見 雄哉 and 柿原 慧遵 and 加藤 明 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン酵素USP8はレンチウイルス粒子へのウイルスRNAの動員を阻害することによってウイルスの増殖を防ぐ}, booktitle = {}, year = 2021, } @inproceedings{CTT100875225, author = {柿原慧遵 and 浅水謙吾 and 森次圭 and 北口哲也 and 遠藤彬則 and 木寺詔記 and 池口満徳 and 駒田雅之 and 福嶋俊明}, title = {脱ユビキチン化酵素USP8の自己阻害機構とクッシング病関連変異によるその解除}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100853019, author = {福嶋俊明 and 遠藤彬則 and 川口紘平 and 円由香 and 駒田雅之}, title = {クッシング病の治療薬開発を目指したUSP8-STAM1複合体を作用点とするACTH分泌制御物質の開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100813515, author = {Keijun Kakihara and Kengo Asamizu and Akinori Endo and Kei Moritsugu and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {The enzyme activity of USP8 is regulated by the intramolecular interaction of the USP domain and the WW domain}, booktitle = {}, year = 2019, } @inproceedings{CTT100813520, author = {Toshiaki Fukushima and Yuka Madoka and Akinori Endo and Kohei Kawaguchi and Saki Arakaki and Masayuki Komada}, title = {Constitutive formation of USP8-STAM1 complex plays an important role in the onset of Cushing’s disease}, booktitle = {}, year = 2019, } @inproceedings{CTT100813519, author = {Keijun Kakihara and Kengo Asamizu and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {A novel autoinhibitory mechanism of ubiquitin-specific protease 8 activity via the intramolecular interaction}, booktitle = {}, year = 2019, } @inproceedings{CTT100813518, author = {Satomi Naito and Akinori Endo and Kimitoshi Denda and Yuka Madoka and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {Nrk prevents hyperplasia by modulating CK2-PTEN-Akt signaling pathway}, booktitle = {}, year = 2019, } @inproceedings{CTT100813514, author = {Satomi Naito and Akinori Endo and Kimitoshi Denda and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {Nik-related kinase is regulated by quality control ubiquitin ligase CHIP}, booktitle = {}, year = 2019, } @inproceedings{CTT100813525, author = {Keijun Kakihara and Kengo Asamizu and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {A novel autoinhibitory mechanism of ubiquitin-specific protease 8 activity via the intramolecular interaction}, booktitle = {}, year = 2019, } @inproceedings{CTT100813526, author = {柿原 慧遵 and 浅水 謙吾 and 遠藤 彬則 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン化酵素 USP8 の自己活性抑制機構}, booktitle = {}, year = 2019, } @inproceedings{CTT100813529, author = {柿原慧遵 and 浅水謙吾 and 遠藤彬則 and 駒田雅之 and 福嶋俊明}, title = {脱ユビキチン化酵素USP8の自己活性抑制機構}, booktitle = {}, year = 2019, } @inproceedings{CTT100813533, author = {Akinori Endo and Toshiaki Fukushima and Masayuki Komada}, title = {A deubiquitinase USP8, a master regulator of endosome-centered membrane traffic, controls inter-cellular signal transduction.}, booktitle = {}, year = 2018, } @inproceedings{CTT100813532, author = {Satomi Naito and Akinori Endo and Toshiaki Fukushima and Kimitoshi Denda and Akira Kato and Masayuki Komada}, title = {Molecular mechanisms underlying the control of Nrk protein levels and Nrk-mediated anti-proliferation effects}, booktitle = {}, year = 2018, } @inproceedings{CTT100813531, author = {Takahiro Sawada and Kazuya Inoko and Kohei Kawaguchi and Akinori Endo and Yasushi Saeki and Keiji Tanaka and Toshiaki Fukushima and Masayuki Komada}, title = {Nuclear localization mechanism of deubiquitinating enzyme USP8 in Cushing’s disease}, booktitle = {}, year = 2018, } @inproceedings{CTT100813535, author = {福嶋俊明 and 澤田崇広 and 猪子和也 and 待鳥卓 and 遠藤彬則 and 駒田雅之}, title = {脱ユビキチン化酵素USP8の遺伝子変異に起因するACTH過剰産生の分子機構}, booktitle = {}, year = 2018, } @inproceedings{CTT100813538, author = {待鳥 卓 and 猪子 和也 and 川口 紘平 and 遠藤 彬則 and 福嶋 俊明 and 駒田 雅之}, title = {USP8 遺伝子のゲノム編集によるCushing 病モデル細胞の作製と解析}, booktitle = {}, year = 2018, } @inproceedings{CTT100813539, author = {Kohei Kawaguchi and Akinori Endo and Toshiaki Fukushima and Masayuki Komada}, title = {Ubiquitin-specific protease 8 suppresses collagen secretion by deubiquitinating Sec31}, booktitle = {}, year = 2018, } @inproceedings{CTT100813540, author = {Xie Xuan and Shunsuke Matsumoto and Akinori Endo and Toshiaki Fukushima and Hiroyuki Kawahara and Yasushi Saeki and Masayuki Komada}, title = {Deubiquitinases USP5 and USP13 are recruited to and regulate heat-induced stress granules by deubiquitinating activities.}, booktitle = {}, year = 2018, } @inproceedings{CTT100745534, author = {田中利明 and 駒田雅之}, title = {母性Cyclin E-DNMT1新規複合体によるツメガエル尾部形成のエピジェネティックな制御}, booktitle = {}, year = 2016, } @inproceedings{CTT100724444, author = {卯尾和音 and 田中利明 and 駒田雅之}, title = {脱ユビキチン化酵素USP25におけるユビキチン結合モチーフUIMの機能}, booktitle = {}, year = 2015, } @inproceedings{CTT100712753, author = {駒田雅之}, title = {脱ユビキチン化酵素USP8の機能獲得型変異がクッシング病を引き起こす}, booktitle = {ACTH Related Peptides}, year = 2015, } @misc{CTT100853023, author = {Keijun Kakihara and Kengo Asamizu and Kei Moritsugu and Masahide Kubo and Tetsuya Kitaguchi and Akinori Endo and Akinori Kidera and Mitsunori Ikeguchi and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain}, year = 2021, } @misc{CTT100774008, author = {川口紘平 and 卯尾和音 and 田中利明 and 駒田雅之}, title = {脱ユビキチン化酵素の基質特異性改変に成功}, year = 2017, } @misc{CTT100774010, author = {Kohei Kawaguchi and Kazune Uo and Toshiaki Tanaka and Masayuki Komada.}, title = {Choosing the right substrate for the right function: role of ubiquitin-interacting motifs on ubiquitin-specific proteases}, year = 2017, } @misc{CTT100774011, author = {川口紘平 and 卯尾和音 and 田中利明 and 駒田雅之}, title = {脱ユビキチン化酵素の基質特異性を改変することに成功-複雑なタンパク質の制御機構の一端を解明-}, year = 2017, } @misc{CTT100774009, author = {川口紘平 and 卯尾和音 and 田中利明 and 駒田雅之}, title = {脱ユビキチン化酵素の基質特異性を改変することに成功 ―複雑なタンパク質の制御機構の一端を解明―}, year = 2017, } @misc{CTT100745528, author = {柳川 享世 and 傳田 公紀 and 稲谷 卓也 and 田中 利明 and 福嶋 俊明 and Nobue Kumaki and 稲垣 豊 and 駒田 雅之}, title = {乳がんを抑制する新たな遺伝子を発見}, year = 2016, } @misc{CTT100745527, author = {柳川 享世 and 傳田 公紀 and 稲谷 卓也 and 田中 利明 and 福嶋 俊明 and Nobue Kumaki and 稲垣 豊 and 駒田 雅之}, title = {乳がんを抑制する新たな遺伝子を発見―ヒト乳がんの診断・治療への応用に期待―}, year = 2016, } @misc{CTT100712749, author = {駒田雅之}, title = {脱ユビキチン化酵素によるエンドサイトーシス制御と遺伝子疾患}, year = 2016, } @misc{CTT100712754, author = {Masayuki Komada}, title = {Decoding the genetic basis of Cushing's disease: USP8 in the spotlight}, year = 2015, } @misc{CTT100712757, author = {駒田雅之}, title = {見えてきたユビキチンを介する核小体の多彩な機能}, year = 2015, } @misc{CTT100712755, author = {駒田雅之}, title = {難病“クッシング病”発症の分子メカニズム}, year = 2015, } @misc{CTT100712756, author = {駒田雅之}, title = {脱ユビキチン化酵素USP8の機能獲得型変異がクッシング病を引き起こす}, year = 2015, } @misc{CTT100712758, author = {Masayuki Komada}, title = {The ubiquitin code and its decoding machinery in the endocytic pathway}, year = 2013, } @misc{CTT100712759, author = {駒田雅之}, title = {ユビキチン化によるFrizzledのリソソーム分解を介したWntシグナル強度の制御}, year = 2013, } @misc{CTT100712760, author = {Masayuki Komada}, title = {Balanced ubiquitination determines cellular responsiveness to extracellular stimul}, year = 2012, } @misc{CTT100712761, author = {駒田雅之}, title = {ユビキチン化による核小体の構造と機能の制御}, year = 2011, } @misc{CTT100712764, author = {駒田雅之}, title = {軸索に特異的なスペクトリン細胞膜骨格の機能}, year = 2010, } @misc{CTT100712763, author = {駒田雅之}, title = {脱ユビキチン化酵素群の細胞機能}, year = 2010, } @misc{CTT100712762, author = {駒田雅之}, title = {受容体のユビキチン化と脱ユビキチン化を介した細胞のWnt応答性の制御}, year = 2010, } @misc{CTT100712765, author = {駒田雅之}, title = {核小体の機能のユビキチンダイナミクスによる制御}, year = 2009, } @misc{CTT100712766, author = {駒田雅之}, title = {ユビキチン修飾系による細胞質分裂の制御}, year = 2009, } @misc{CTT100712767, author = {Masayuki Komada}, title = {Controlling receptor downregulation by ubiquitination and deubiquitination}, year = 2008, } @misc{CTT100712768, author = {駒田雅之}, title = {エンドソームと細胞質分裂の接点−ユビキチン化/脱ユビキチン化による調節}, year = 2008, } @misc{CTT100712769, author = {Masayuki Komada}, title = {Regulation of endosomal cargo sorting by deubiquitinating enzymes}, year = 2007, } @misc{CTT100712770, author = {駒田雅之}, title = {神経繊維ランビエ絞輪部近傍の軸索構築に関するタンパク質間相互作用}, year = 2007, } @misc{CTT100595094, author = {Masayuki Komada}, title = {Hepatocyte growth factor/scatter factor受容体の構造と機能に関する研究}, year = 1994, } @misc{CTT100596555, author = {Masayuki Komada}, title = {ラットII型ホスホリパーゼA2の遺伝子のクローニングと構造解析}, year = 1990, } @phdthesis{CTT100595094, author = {Masayuki Komada}, title = {Hepatocyte growth factor/scatter factor受容体の構造と機能に関する研究}, school = {東京大学}, year = 1994, } @mastersthesis{CTT100596555, author = {Masayuki Komada}, title = {ラットII型ホスホリパーゼA2の遺伝子のクローニングと構造解析}, school = {東京大学}, year = 1990, }