@article{CTT100885606, author = {Daiki Nakatsu and Rina Kunishige and Yuki Taguchi and Naeko Shinozaki-Narikawa and Kishiko Osaka and Kayo Yokomizo and Mami Ishida and Shunsuke Takei and Shoko Yamasaki and Keita Hagiya and Kotaro Hattori and Tadashi Tsukamoto and Masayuki Murata and Fumi Kano}, title = {BMP4-SMAD1/5/9-RUNX2 pathway activation inhibits neurogenesis and oligodendrogenesis in Alzheimer’s patients’ iPSCs in senescence-related conditions}, journal = {Stem Cell Reports}, year = 2023, } @article{CTT100885146, author = {Mikio Furuse and  Daiki Nakatsu and  Wendy Hempstock and  Shiori Sugioka and  Noriko Ishizuka and  Kyoko Furuse and  Taichi Sugawara and  Yugo Fukazawa and  Hisayoshi Hayashi}, title = {Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells}, journal = {Cell Structure and Function}, year = 2023, } @article{CTT100858020, author = {Yoshiyuki Noguchi and Fumi Kano and Nobuhiko Maiya and Chisako Iwamoto and Shoko Yamasaki and Yosuke Otsubo and Daiki Nakatsu and Rina Kunishige and Masayuki Murata}, title = {Microscopic image-based covariation network analysis for actin scaffold-modified insulin signaling}, journal = {iScience}, year = 2021, } @article{CTT100806767, author = {Daiki Nakatsu and Fumi Kano and Naeko Shinozaki-Narikawa and Masayuki Murata}, title = {Pyk2-dependent phosphorylation of LSR enhances localization of LSR and tricellulin at tricellular tight junctions}, journal = {PLOS ONE}, year = 2019, } @article{CTT100773136, author = {Yuta Horiuchi and Daiki Nakatsu and Fumi Kano and Masayuki Murata}, title = {Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells.}, journal = {Cellular Signalling}, year = 2017, } @article{CTT100858030, author = {Yuki Taguchi and Koichi Imaoka and Michiyo Kataoka and Akihiko Uda and Daiki Nakatsu and Sakuya Horii-Okazaki and Rina Kunishige and Fumi Kano and Masayuki Murata}, title = {Yip1A, a Novel Host Factor for the Activation of the IRE1 Pathway of the Unfolded Protein Response during Brucella Infection}, journal = {PLOS Pathogens}, year = 2015, } @article{CTT100773084, author = {Daiki Nakatsu and Yuta Horiuchi and Fumi Kano and Yoshiyuki Noguchi and Taichi Sugawara and Iseki Takamoto and Naoto Kubota and Takashi Kadowaki and Masayuki Murata}, title = {L-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2.}, journal = {Proceedings of the National Academy of Sciences of the United States of America, Proc. Natl. Acad. Sci. U. S. A, PNAS, PRONAS}, year = 2015, } @article{CTT100773134, author = {Daiki Nakatsu and Fumi Kano and Yuki Taguchi and Taichi Sugawara and Takashi Nishizono and Kiyotaka Nishikawa and Yukako Oda and Mikio Furuse and Masayuki Murata}, title = {JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.}, journal = {Genes to Cells}, year = 2014, } @article{CTT100773140, author = {Fumi Kano and Daiki Nakatsu and Yoshiyuki Noguchi and Akitsugu Yamamoto and Masayuki Murata}, title = {A resealed-cell system for analyzing pathogenic intracellular events: perturbation of endocytic pathways under diabetic conditions.}, journal = {PLOS ONE}, year = 2012, } @article{CTT100773149, author = {Taichi Sugawara and Daiki Nakatsu and Hiroaki Kii and Nobuhiko Maiya and Atsuhiro Adachi and Akitsugu Yamamoto and Fumi Kano and Masayuki Murata}, title = {PKCδ and ε regulate the morphological integrity of the ER-Golgi intermediate compartment (ERGIC) but not the anterograde and retrograde transports via the Golgi apparatus.}, journal = {BBA - Molecular Cell Research}, year = 2012, } @inproceedings{CTT100894386, author = {中津大貴 and 國重莉奈 and 田口由起 and 成川 - 篠崎‌苗子 and 大坂企志子 and 横溝佳代 and 石田真美 and 武居俊輔 and 山﨑聖子 and 萩屋啓太 and 服部功太郎 and 塚本忠 and 村田昌之 and 加納ふみ}, title = {患者由来 iPS 細胞を用いたアルツハイマー依存的神経新生不全モデルの構築と構築モデル を用いた神経新生不全回復薬の同定}, booktitle = {}, year = 2023, } @inproceedings{CTT100894390, author = {國重 莉奈 and 野口 誉之 and 米谷 信彦 and 中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {薬剤に対する細胞応答を超早期に捉える新規タンパク質ネットワーク解析法}, booktitle = {}, year = 2023, } @inproceedings{CTT100894387, author = {角田貴史 and 中津大貴 and 村田昌之 and 加納ふみ}, title = {PKM1はSMAD4不活性化によるPYK2発現促進を介してトリセルラータイトジャンクションへ構成タンパク質を局在化させる}, booktitle = {}, year = 2023, } @inproceedings{CTT100894397, author = {國重 莉奈 and 野口 誉之 and 米谷 信彦 and 中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {シグナル伝達系タンパク質の時空間ダイナミクスを捉える新規ネットワーク解析法の開発と薬効評 価への応用}, booktitle = {}, year = 2023, } @inproceedings{CTT100884141, author = {國重 莉奈 and 野口 誉之 and 米谷 信彦 and 中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {「細胞状態」の時空間的変化を活写する共変動ネットワーク解析法による薬効評価}, booktitle = {}, year = 2022, } @inproceedings{CTT100883672, author = {國重 莉奈 and 野口 誉之 and 米谷 信彦 and 中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {インスリン刺激により一過性に形成されるアクチンドメインはグリコーゲン合成の開始場となる: 細胞状態を活写する新規ネットワーク解析法の応用例}, booktitle = {}, year = 2022, } @inproceedings{CTT100885147, author = {米谷 信彦 and 野口 誉之 and 加納 ふみ and 岩本 智沙子 and 山﨑 聖子 and 大坪 洋介 and 中津 大貴 and 國重 莉奈 and 村田 昌之}, title = {蛋白質の細胞内局在情報を活用したシグナル伝達系分析手法の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100883440, author = {野口 誉之 and 國重 莉奈 and 米谷 信彦 and 中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {PLOM-CON 解析: 細胞形態およびタンパク質の修飾状態を考慮した細胞内状態の時系列変化の新規推定法}, booktitle = {}, year = 2022, } @inproceedings{CTT100883439, author = {國重 莉奈 and 野口 誉之 and 米谷 信彦 and 中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {インスリン刺激により一過性に形成される シグナリング「ハブ」としてのアクチンドメイン: PLOM-CON解析法を用いた新機能の予測と解明}, booktitle = {}, year = 2022, } @inproceedings{CTT100884095, author = {野口 誉之 and 加納 ふみ and 米谷 信彦 and 岩本 智沙子 and 山崎 聖子 and 大坪 洋介 and 中津 大貴 and 國重 莉奈 and 村田 昌之}, title = {蛋白質の細胞内局在情報を活用したシグナル伝達系分析手法の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100863219, author = {中津大貴 and 成川 - 篠崎‌苗子 and 村田昌之 and 加納‌ふみ}, title = {PYK2はバイセルラータイトジャンクションへのトリセルラータイトジャンクション構成タン パク質の拡散を抑制する}, booktitle = {}, year = 2021, } @inproceedings{CTT100826406, author = {中津大貴 and 成川 - 篠崎‌苗子 and 村田昌之 and 加納‌ふみ}, title = {PYK2はLSRのリン酸化亢進を介してトリセルラータイトジャンクションへのLSRとTricellulinの局在化を促進する}, booktitle = {}, year = 2020, } @inproceedings{CTT100855429, author = {Fumi Kano and Yoshiyuki Noguchi and Daiki Nakatsu and Masayuki Murata}, title = {Microscopic image-based technologies for analyzing spatiotemporal regulation of protein functions}, booktitle = {}, year = 2020, } @inproceedings{CTT100813652, author = {中津 大貴 and 村田 昌之 and 加納 ふみ}, title = {M型ピルビン酸産生酵素PKM1の減少は小胞体ストレス依存的な膵臓β細胞死を促進する}, booktitle = {}, year = 2019, } @inproceedings{CTT100813654, author = {中津 大貴 and 堀内 雄太 and 加納 ふみ and 村田 昌之}, title = {M型ピルビン酸産生酵素PKM1は膵臓β細胞の小胞体ストレス依存的な細胞死を抑制する}, booktitle = {}, year = 2017, } @inproceedings{CTT100813653, author = {中津 大貴 and 村田 昌之}, title = {細胞外システインの増加が膵臓β細胞のインスリン分泌不全を引き起こす}, booktitle = {}, year = 2017, } @inproceedings{CTT100813655, author = {中津 大貴 and 堀内 雄太 and 加納 ふみ and 野口 誉之 and 菅原 太一 and 高本 偉碩 and 窪田 直人 and 門脇 孝 and 村田 昌之}, title = {L-システインによるPKM2タンパク質不活性化を介した可逆的なインスリン分泌抑制:制御機構の生化学的解析}, booktitle = {}, year = 2015, } @misc{CTT100844695, author = {加納ふみ and 中津大貴 and 村田昌之}, title = {アルツハイマー疾患モデル神経細胞及びその製造方法、並びにその神経細胞を用いたアルツハイマー病作用薬物のスクリーニング方法}, howpublished = {登録特許}, year = 2023, month = {}, note = {特願2019-088602(2019/05/08), 特開2020-182423(2020/11/12), 特許第7333579号(2023/08/17)} }