@article{CTT100703323, author = {Hee-Jin Jeong and Takuya Kawamura and Jinhua Dong and Hiroshi Ueda}, title = {Qーbodies from recombinant single-chain Fv fragment with better yield and expanded palette of fluorophores}, journal = {ACS Sensors}, year = 2015, } @article{CTT100698631, author = {M. Kurihara and Y. Ohmuro-Matsuyama and K. Ayabe and T. Yamashita and H. Yamaji and H. Ueda}, title = {Ultra sensitive firefly luciferase-based protein-protein interaction assay (FlimPIA) attained by hinge region engineering and optimized reaction conditions}, journal = {Biotechnol. J.}, year = 2015, } @article{CTT100698630, author = {M. Komatsu and J. Dong and H. Ueda and R. Arai}, title = {Crystal structure of Fab fragment of an anti-osteocalcin C-terminal peptide antibody KTM219}, journal = {Photon Factory Act. Rep.}, year = 2015, } @article{CTT100711189, author = {J. Gholami and M. Manteghian and A. Badiei and M. Javanbakht and H. Ueda}, title = {Label free detection of vitamin B12 based on fluorescence quenching of graphene oxide nanolayer}, journal = {Fullerenes, Nanotubes and Carbon Nanostructures}, year = 2015, } @article{CTT100690553, author = {Jinhua Dong and Tomoki Kojima and Hiroyuki Ohashi and Hiroshi Ueda}, title = {Optimal fusion of antibody binding domains resulted in higher affinity and wider specificity}, journal = {J BIOSCI BIOENG}, year = 2015, } @article{CTT100685489, author = {H.J. Jeong and S. Itayama and H. Ueda}, title = {A signal-on fluorosensor based on quench-release principle for sensitive detection of antibiotic rapamycin}, journal = {Biosensors}, year = 2015, } @article{CTT100685490, author = {C.I. Chung and R. Makino and J. Dong and H. Ueda}, title = {Open flower fluoroimmunoassay: a general method to make fluorescent protein-based immunosensor probes}, journal = {ANAL CHEM}, year = 2015, } @article{CTT100685494, author = {K. Hayashi and Y. Tomozoe and K. Nagai and K. Matsuba and M. Mitsumori and Y. Hiraishi and T. Matsumura and 上田 宏 and 神谷 典穂}, title = {イムノアッセイを目的とした融合タンパク質試薬の設計と生産プロセスの最適化}, journal = {}, year = 2015, } @inproceedings{CTT100724638, author = {Hiroshi Ueda and Hideki Yamaji and Yuki Ohmuro-Matsuyama}, title = {Hinge region engineering of firefly luciferases for robust protein-protein interaction assay FlimPIA}, booktitle = {}, year = 2015, } @inproceedings{CTT100724643, author = {大室有紀 and 五味恵子 and 山地秀樹 and 上田宏}, title = {蛋白質間相互作用検出系FlimPIAの実用化を目指したプローブの熱安定性向上}, booktitle = {BMB2015要旨集}, year = 2015, } @inproceedings{CTT100724641, author = {Chan-I Chung and Yuki Ohmuro-Matsuyama and Yuko Sato and Hiroshi Kimura and Hiroshi Ueda}, title = {Development of intrabody-based FRET probe for monitoring histone H3 acetylation in living cells}, booktitle = {}, year = 2015, } @inproceedings{CTT100724640, author = {Shitao Zhao and Hee-Jin Jeong and Koichi Okumura and Hiroshi Ueda}, title = {Fast and sensitive detection of a neonicotinoid insecticide imidacloprid with a reagentless immunoassay reagent Quenchbody}, booktitle = {}, year = 2015, } @inproceedings{CTT100724639, author = {Hiroshi Ueda and Hee-Jin Jeong and Takuya Kawamura and Manami Iida and Yumi Kawahigashi and Mutsumi Takigawa and Chan-I Chung and Jinhua Dong and Masuo Kondoh}, title = {Development of Quenchbody to image and quantify tumor-associated membrane protein claudin}, booktitle = {}, year = 2015, } @inproceedings{CTT100724633, author = {鄭熙陳 and 松本 健司 and 板山 修也 and 阿部 亮二 and 董金華 and 新藤充 and 上田 宏}, title = {抗体タンパク質からの蛍光免疫センサーQuenchbodyの構築}, booktitle = {BMB2015要旨集}, year = 2015, } @inproceedings{CTT100724637, author = {董 金華 and 座古 保 and 上田 宏}, title = {新規免疫測定素子UQ-bodyを用いたアミロイドβオリゴマーの蛍光検出}, booktitle = {BMB2015要旨集}, year = 2015, } @inproceedings{CTT100724182, author = {上田宏 and 五味恵子 and 山地秀樹 and 大室有紀}, title = {ヘイケボタル酵素を用いた蛋白質間相互作用検出系FlimPIAの構築}, booktitle = {}, year = 2015, } @inproceedings{CTT100724183, author = {大室有紀 and 五味恵子 and 山地秀樹 and 上田宏}, title = {蛋白質間相互作用検出系FlimPIAにおけるプローブの熱安定性向上}, booktitle = {}, year = 2015, } @inproceedings{CTT100724622, author = {飯田愛未 and 川東 祐美 and 滝川 睦美 and 鍾 蝉伊 and 董金華 and 近藤昌夫 and 上田 宏}, title = {がん関連膜蛋白質クローディン可視化のためのQuenchbodyの開発}, booktitle = {第9回バイオ関連化学シンポジウム要旨集}, year = 2015, } @inproceedings{CTT100734827, author = {大河内 美奈 and 武藤 正記 and 田中 祐圭 and 上田 宏 and 小野寺 武 and 都甲 潔 and }, title = {TNT抗体の抗原結合部位解析に基づいたペプチドプローブの設計}, booktitle = {}, year = 2015, } @inproceedings{CTT100724630, author = {上田宏}, title = {抗原結合により光る抗体Q-body の開発とそのバイオ計測への応用}, booktitle = {第67回日本生物工学会大会要旨集}, year = 2015, } @inproceedings{CTT100724625, author = {鄭熙陳 and 松本健司 and 板山修也 and 阿部亮二 and 董金華 and 新藤充 and 上田宏}, title = {光化学修飾法によるQuenchbodyの構築}, booktitle = {第9回バイオ関連化学シンポジウム要旨集}, year = 2015, } @inproceedings{CTT100695392, author = {上田宏}, title = {Quenchbodies - Quench-based antibody probes that emit antigen-dependent fluorescence}, booktitle = {Immunome Research}, year = 2015, } @inproceedings{CTT100724588, author = {Hiroshi Ueda and Hee-Jin Jeong and Yuki Ohmuro-Matsuyama and Jinhua Dong}, title = {Development of Biosensor Proteins Utilizing Fluorescence Quenching and Bioluminescent Reactions}, booktitle = {Program, 2015 International Symposium & Annual Meeting, KMB}, year = 2015, } @inproceedings{CTT100724616, author = {河村拓哉 and 川東 祐美 and 滝川 睦美 and 鍾 蝉伊 and 董金華 and 近藤昌夫 and 上田 宏}, title = {がん関連膜蛋白質クローディンを認識するQuenchbodyの開発}, booktitle = {第15回日本蛋白質科学会年会要旨集}, year = 2015, } @inproceedings{CTT100724593, author = {董 金華 and ジョンヒジン and 上田 宏}, title = {アミノ転移反応を利用したQuenchbodyの構築}, booktitle = {第15回日本蛋白質科学会年会要旨集}, year = 2015, } @inproceedings{CTT100725462, author = {上田 宏 and 阿部亮二 and 大橋広行}, title = {夢の免疫測定素子Quenchbody(Q-body)について-食品安全への応用を中心に}, booktitle = {}, year = 2015, } @misc{CTT100711194, author = {上田宏}, title = {抗体のセンサー化で生命現象を探る}, year = 2015, } @misc{CTT100711226, author = {Hiroshi Ueda}, title = {Improving Medical Care with Engineering}, year = 2015, } @misc{CTT100711191, author = {董 金華 and 上田 宏}, title = {生物発光タンパク質センサーを用いた薬剤のモニタリング}, year = 2015, } @misc{CTT100711190, author = {阿部 亮二 and 上田 宏}, title = {抗体断片の蛍光技術を用いた迅速・簡便な検査キットの開発}, year = 2015, } @misc{CTT100744874, author = {上田宏 and 鄭熙陳 and 董金華 and 阿部 亮二}, title = {抗体のヌクレオチド結合部位(NBS)を利用して蛍光標識された抗体}, howpublished = {公開特許}, year = 2017, month = {}, note = {特願2015-174075(2015/09/03), 特開2017-049184(2017/03/09)} } @misc{CTT100701098, author = {上田宏 and 大室 有紀 and 黒澤 恵子}, title = {ルシフェラーゼ変異体及びそれを用いた分子間相互作用検出方法}, howpublished = {公開特許}, year = 2015, month = {}, note = {特願2015-079444(2015/04/08), 特開2015-211668(2015/11/26)} }