@article{CTT100811952, author = {N. Yamada and Y. Honda and H. Takemoto and T. Nomoto and M. Matsui and K. Tomoda and M. Konno and H. Ishii and M. Mori and N. Nishiyama}, title = {Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism}, journal = {Scientific Reports}, year = 2017, } @article{CTT100751735, author = {Qixian Chen and Kensuke Osada and Zhishen Ge and Satoshi Uchida and Theofilus A. Tockary and Anjaneyulu Dirisala and Akitsugu Matsui and Kazuko Toh and Kaori M. Takeda and Xueying Liu and Takahiro Nomoto and Tekihiko Ishii and Makoto Oba and Yu Matsumoto and Kazunori Kataoka}, title = {Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting}, journal = {Biomaterials}, year = 2017, } @article{CTT100752048, author = {Chih-Hao Huang and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {Utility of 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-conjugated Polymer System}, journal = {ChemMedChem}, year = 2017, } @inproceedings{CTT100773989, author = {Naoki Yamada and Yuto Honda and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Glutamine-Functionalized Polymer for Tumor-Selective High Affinity by Sensing Dense Glutamine Transporters Associated with Aberrant Metabolism}, booktitle = {}, year = 2017, } @inproceedings{CTT100773988, author = {Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {2-nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate}, booktitle = {}, year = 2017, } @inproceedings{CTT100773987, author = {山田直生 and 本田雄士 and 武元宏泰 and 野本貴大 and 松井 誠 and 友田敬士郎 and 西山伸宏}, title = {がん選択的に相互作用するグルタミン担持高分子の創製と機能評価}, booktitle = {}, year = 2017, } @inproceedings{CTT100773983, author = {左久間隼矢 and Abdul-Hackam RANNEH and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {腫瘍指向性ステルス高分子の開発とDDSへの応 用-ベタイン構造内アニオン性基の影響-}, booktitle = {}, year = 2017, } @inproceedings{CTT100773985, author = {武元宏泰 and 稲葉 高徳 and 野本 貴大 and 松井 誠 and 友田 敬士郎 and 西山 伸宏}, title = {糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減}, booktitle = {}, year = 2017, } @inproceedings{CTT100773982, author = {真貝 太規 and 山田直生 and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発}, booktitle = {}, year = 2017, } @inproceedings{CTT100773984, author = {Dou Xuebo and 野本 貴大 and 武元 宏泰 and 松井 誠 and 友田 敬士郎 and 西山 伸宏}, title = {光増感剤結合型高分子における多岐環状RGDペプチドの腫瘍集積性と腫瘍内分布への効果の検討}, booktitle = {}, year = 2017, } @inproceedings{CTT100752117, author = {武元 宏泰 and 稲葉 高徳 and 野本 貴大 and 松井 誠 and 友田 敬士郎 and 西山 伸宏}, title = {ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上}, booktitle = {}, year = 2017, } @inproceedings{CTT100752165, author = {Hiroyasu Takemoto and Huang Chih-Hao and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {2-Nitrobenzenesulfonamide Group that Responds to Intracellular Redox Potential with Enhanced Photostability for a Construction of Polymer-siRNA Conjugate System}, booktitle = {}, year = 2017, } @inproceedings{CTT100752093, author = {劉暁夢 and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発}, booktitle = {}, year = 2017, } @inproceedings{CTT100752095, author = {左久間隼矢 and RannehA-Hackam and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-}, booktitle = {}, year = 2017, } @inproceedings{CTT100752091, author = {真貝太規 and 山田直生 and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発}, booktitle = {}, year = 2017, } @inproceedings{CTT100752096, author = {Hiroyasu Takemoto and Chih Hao Huang and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {2-nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system}, booktitle = {}, year = 2017, } @inproceedings{CTT100752097, author = {Naoki Yamada and Yuto Honda and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters}, booktitle = {}, year = 2017, } @inproceedings{CTT100752161, author = {Yuto Honda and Naoki Yamada and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism.}, booktitle = {}, year = 2017, } @inproceedings{CTT100752159, author = {Hiroyasu Takemoto and Huang Chih-Hao and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate.}, booktitle = {}, year = 2017, } @inproceedings{CTT100752155, author = {Ranneh Hackam and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Development of stealth shell based on polycarboxybetaine structure tuned to selectively interact with cells in tumor extracellular acidic pH}, booktitle = {}, year = 2017, } @inproceedings{CTT100752152, author = {Takanori Inaba and Hiroyasu Takemoto and Makoto Matsui and Takahiro Nomoto and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Enhanced antitumor activity and reduced gastrointestinal toxicity of gemcitabine based on conjugation with biocompatible polymer via acetal linker}, booktitle = {}, year = 2017, } @inproceedings{CTT100752150, author = { Tsukasa Nishimori and Naoki Yamada and Hiroyasu Takemoto and Kentaro Suina and Juntaro Yamasaki and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Osamu Nagano and Hideyuki Saya and Nobuhiro Nishiyama}, title = {Development of intravenously injectable sulfasalazine derivatives to treat stem-like cancer cells}, booktitle = {}, year = 2017, } @inproceedings{CTT100752149, author = {Chi-Hao Huang and Hiroyasu Takemoto and Takahiro Nomoto and Keishiro Tomoda and Makoto Matsui and Nobuhiro Nishiyama}, title = {2-nitrobenzenesulfonamide group as a new chemical linker with redox sensitivity for siRNA-conjugated polymer system}, booktitle = {}, year = 2017, } @misc{CTT100815579, author = {西山伸宏 and 武元宏泰 and Abdul-Hackam RANNEH and 友田敬士郎 and 野本貴大 and 松井誠}, title = {pH応答性ポリマー及び薬物送達システム}, howpublished = {登録特許}, year = 2021, month = {}, note = {特願2018-556597(2017/12/05), 再表2018/110366(2019/10/24), 特許第6995375号(2021/12/17)} } @misc{CTT100806614, author = {西山伸宏 and El Muttaqien SJAIKHURRIZAL and 野本貴大 and 武元宏泰 and 松井誠 and 友田敬士郎}, title = {温度応答性ポリマー及びそれを含む組成物}, howpublished = {公開特許}, year = 2019, month = {}, note = {特願2017-211893(2017/11/01), 特開2019-085438(2019/06/06)} } @misc{CTT100806622, author = {西山伸宏 and 武元宏泰 and 野本貴大 and 友田敬士郎 and 松井誠 and 山田直生 and 本田雄士 and 森 正樹 and 石井 秀始 and 今野 雅允}, title = {グルタミントランスポーターと多価結合することができるリガンド、及び当該リガンドを含む組成物}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2018-535630(2017/08/17), 特開(再表)2018-037996(2019/06/20), 特許第7076104号(2022/05/19)} } @misc{CTT100808501, author = {西山伸宏 and 中村浩之 and 武元宏泰 and 野本貴大 and 片岡 一則  and Mi Peng  and Horacio Cabral  and 柳衛 宏宣 and Novriana Dewi  and 黒澤 渉 and 姥貝 吏紗 and 北原 吉朗  and 須賀 泰世 }, title = {ホウ素クラスター結合ペプチド化合物}, howpublished = {公開特許}, year = 2019, month = {}, note = {特願2018-507416(2017/03/23), 再表2017/164334(2019/02/28)} } @misc{CTT100830142, author = {西山伸宏 and 武元宏泰 and 稲葉高徳 and 野本貴大 and 松井誠 and 友田敬士郎}, title = {薬物送達用担体及び薬物送達システム}, howpublished = {公開特許}, year = 2020, month = {}, note = {特願2017-029264(2017/02/20), 特開2020-063191(2020/04/23)} } @misc{CTT100789761, author = {西山伸宏 and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 山田直生 and 西森司 and 佐谷 秀行 and 永野 修  and 土橋 賢司 and 推名 健太郎}, title = {抗腫瘍剤}, howpublished = {登録特許}, year = 2020, month = {}, note = {特願2017-560416(2017/01/05), 再表2017/119462(2018/11/01), 特許第6803589号(2020/12/03)} } @misc{CTT100761475, author = {西山伸宏 and 武元宏泰 and Chih-Hao HUANG  and 野本貴大 and 友田敬士郎 and 松井誠}, title = {結合体}, howpublished = {公開特許}, year = 2017, month = {}, note = {特願2016-113664(2016/06/07), 特開2017-218408(2017/12/14)} }