@article{CTT100837189, author = {Kazuki Harada and Takami Chihara and Yuki Hayasaka and Marie Mita and Mai Takizawa and Kentaro Ishida and Mary Arai and Saki Tsuno and Mitsuharu Matsumoto and Takeshi Ishihara and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi}, title = {Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.}, journal = {Sci Rep}, year = 2020, } @article{CTT100838310, author = {Yoshitaka HARADA and Yuki OHMURO-MATSUYAMA and Mika TSUNA and Hiroshi UEDA}, title = {An Open Sandwich Immunochromatography for Non-competitive Detection of Small Antigens}, journal = {Analytical Sciences}, year = 2020, } @article{CTT100836504, author = {Akihito Inoue and Yuki Ohmuro-Matsuyama and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Creation of a Nanobody-Based Fluorescent Immunosensor Mini Q‐body for Rapid Signal-On Detection of Small Hapten Methotrexate}, journal = {ACS Sensors}, year = 2020, } @article{CTT100827505, author = {J. Dong and C. Miyake and T. Yasuda and H. Oyama and I. Morita and T. Tsukahara and M. Takahashi and H.-J. Jeong and T. Kitaguchi and N. Kobayashi and H. Ueda}, title = {PM Q-probe: A fluorescent binding protein that converts many antibodies to a fluorescent biosensor}, journal = {Biosensors and Bioelectronics}, year = 2020, } @article{CTT100830361, author = {L. Chen and R. Tan and Y. Zhou and L. Zhang and S. Zhanga and X. Li and Y. Cong and H. Li and P. Sun and L. Chen and R. Tan and Y. Zhou and L. Zhang and S. Zhang and X. Li and Y. Cong and H. Li and P. Sun and H. Ueda and J. Dong}, title = {Development of an Open Sandwich ELISA for the Detection of Microcystin-LR}, journal = {Microchemical Journal}, year = 2020, } @article{CTT100826337, author = {Hee-Jin Jeong and Jinhua Dong and Chang-Hun Yeom and Hiroshi Ueda}, title = {Synthesis of Quenchbodies for One-Pot Detection of Stimulant Drug Methamphetamine}, journal = {Methods and Protocols}, year = 2020, } @article{CTT100821932, author = {Chungyong Han and Beom K. Choi and Seon-Hee Kim and Su-Jung Sim and Seongeun Han and Bomi Park and Yohei Tsuchiya and Masaki Takahashi and Young H. Kim and Hyeon-Seok Eom and Tetsuya Kitaguchi and Hiroshi Ueda and Byoung S. Kwon}, title = {Polymorphic region-specific antibody for evaluation of affinity-associated profile of chimeric antigen receptor}, journal = {Molecular Therapy: Oncolytics}, year = 2020, } @article{CTT100826198, author = {Shinichi Sato and Masaki Matsumura and Tetsuya Kadonosono and Satoshi Abe and Takafumi Ueno and Hiroshi Ueda and Hiroyuki Nakamura}, title = {Site-selective protein chemical modification of exposed tyrosine residues using tyrosine click reaction}, journal = {Bioconjugate Chemistry}, year = 2020, } @article{CTT100821930, author = {Jinhua Dong and Yuya Oka and Hee-Jin Jeong and Yuki Ohmuro-Matsuyama and Hiroshi Ueda}, title = {Detection and destruction of HER2-positive cancer cells by Ultra Quenchbody-siRNA complex}, journal = {Biotechnology and Bioengineering}, year = 2020, } @article{CTT100814312, author = {Kanai, Y. and Ohmuro-Matsuyama, Y. and Tanioku, M. and Ushiba, S. and Ono, T. and Inoue, K. and Kitaguchi, T. and Kimura, M. and Ueda, H. and Matsumoto, K.}, title = {Graphene Field Effect Transistor-Based Immunosensor for Ultrasensitive Noncompetitive Detection of Small Antigens}, journal = {ACS Sensors}, year = 2020, } @inproceedings{CTT100854628, author = {Ippei Tsujimura and Hiroshi Aihara and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Development of a red fluorescent probe inducing its intensity change by antigen binding.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854627, author = {Hiroshi Aihara and Yanyan Hou and Hiroshi Ueda and Toshiro Ito and Tetsuya Kitaguchi.}, title = {Development of a plant hormone probe employing antibody as molecular recognition domain for visualizing intracellular dynamics.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854630, author = {Jiulong Su and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake and Hiroshi Ueda.}, title = {Development of patrol yeasts for the detection of toxic substances in foods.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854629, author = {Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi.}, title = {Development of turn-on type green fluorescent cAMP biosensors applicable to wide range of cAMP dynamics.}, booktitle = {第43回日本分子生物学会年会要旨集}, year = 2020, } @inproceedings{CTT100854516, author = {Jiulong Su and Yasuyuki Nakamura and Tetsuya Kitaguchi and Jun Ishii and Akihito Kondo and Norihiro Kobayashi and Shiro Miyake and Hiroshi Ueda.}, title = {Development of patrol yeasts for the detection of toxic substances in foods.}, booktitle = {第93回日本生化学会大会要旨集}, year = 2020, } @inproceedings{CTT100854520, author = {井上暁人 and 安田貴信 and 北口哲也 and 上田宏}, title = {蛍光免疫センサーQ-bodyを提示した酵母細胞の構築と抗原検出}, booktitle = {化学工学会第51回秋季大会要旨集}, year = 2020, } @inproceedings{CTT100854518, author = {上田宏 and 董金華 and 三宅千絢 and 安田貴信 and 髙橋昌樹 and 大山浩之 and 森田いずみ and 北口哲也 and 小林典裕}, title = {抗体を蛍光免疫センサーQ-body 化可能なタンパク質PM Q-probe による各種バイオマーカーの測定}, booktitle = {化学工学会第51回秋季大会要旨集}, year = 2020, } @inproceedings{CTT100854510, author = {Yoshiyuki Ueno and Naoya Tochio and Junqian Wang and Tetsuya Kitaguchi and Takanori Kigawa and Hiroshi Ueda.}, title = {Mechanistic analysis of novel immunosensor Hibody to clarify the antigen-dependent protrusion of tag sequence attached to the antibody N-terminus.}, booktitle = {第20回日本蛋白質科学会年会要旨集}, year = 2020, } @inproceedings{CTT100854513, author = {Takanobu Yasuda and Akihito Inoue and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Creation and evaluation of immunosensors that enable ratiometric assay by rapid dual-color labeling of antibody fragments.}, booktitle = {第20回日本蛋白質科学会年会要旨集}, year = 2020, } @inproceedings{CTT100837740, author = {有坂亮汰 and 北口哲也 and 上田宏}, title = {ハイブリドーマ細胞のゲノム編集によるオープンサンドイッチ免疫測定用人工抗体の生産}, booktitle = {化学工学会第85年会要旨集}, year = 2020, } @inproceedings{CTT100814877, author = {上田 宏}, title = {タンパク質工学的手法による各種蛍光・発光免疫センサーの開発}, booktitle = {電気学会 光・量子デバイス研究会「医療・バイオ応用を目指したナノ構造・ナノ界面」要旨集}, year = 2020, } @misc{CTT100877445, author = {上田宏 and 北口哲也 and SuJiulong and 三宅 司郎  and 小林 典裕 }, title = {抗体断片を含む人工受容体を細胞膜に提示した酵母とこれを用いた抗原検出法 }, howpublished = {公開特許}, year = 2022, month = {}, note = {特願2020-145870(2020/08/31), 特開2022-040923(2022/03/11)} } @misc{CTT100869590, author = {上田宏 and 北口哲也 and 大室有紀 and 安田貴信 and 井上暁人}, title = {複数の蛍光色素を結合させたペプチドを用いるホモジニアス免疫測定法}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/021899(2020/06/03), WO 2020/246495(2020/10/12)} } @misc{CTT100869602, author = {上田宏 and 北口哲也 and 大室有紀 and 上野慶行}, title = {レポータータンパク質断片を付加した組換え抗体を用いるホモジニアス免疫測定法}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/020281(2020/05/22), WO 2020/241486(2020/12/03)} } @misc{CTT100865567, author = {上田宏 and 綱 美香  and 原田 義孝 }, title = {低分子化合物の簡易検出法}, howpublished = {公開特許}, year = 2021, month = {}, note = {特願2020-056188(2020/03/26), 特開2021-156695(2021/10/07)} } @misc{CTT100869583, author = {上田宏 and SuJiulong and 北口哲也 and 大室有紀}, title = {ホモジニアス免疫測定法に適した酵素変異体}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/002264(2020/01/23), WO 2020/162203(2020/08/13)} } @misc{CTT100831058, author = {上田宏 and SuJiulong and 北口哲也 and 大室有紀 and Shawn Hoon and Cyrus Beh }, title = {バイオセンサー}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2018-207624(2018/11/02), 特開2020-068746(2020/05/07), 特許第7169582号(2022/11/02)} }