@book{CTT100853162, author = {Marie Mita and Devina Wongso and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi}, title = {Development of a single fluorescent protein-based green glucose indicator by semirational molecular design and molecular evolution.}, publisher = {Springer}, year = 2021, } @article{CTT100863026, author = {H. Li and X. Li and H. Li and H. Dong and X. Yang and H. Ueda and J. Dong}, title = {Quench-release-based Fluorescent Immunosensor for the Rapid Detection of Tumor Necrosis Factor-alpha}, journal = {ACS Omega}, year = 2021, } @article{CTT100863138, author = {Akihito Inoue and Takanobu Yasuda and Bo Zhu and Tetsuya Kitaguchi and Akikazu Murakami and Hiroshi Ueda}, title = {Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface}, journal = {Scientific Reports}, year = 2021, } @article{CTT100862791, author = {Yuki Ohmuro-Matsuyama and Keiko Gomi and Takuya Shimoda and Hideki Yamaji and Hiroshi Ueda}, title = {Improving the stability of protein–protein interaction assay FlimPIA using a thermostabilized firefly luciferase}, journal = {Frontiers in Bioengineering and Biotechnology}, year = 2021, } @article{CTT100861229, author = {Shinichi Sato and Masaki Matsumura and Hiroshi Ueda and Hiroyuki Nakamura}, title = {Preparation of an antigen-responsive fluorogenic immunosensor by tyrosine chemical modification of the antibody complementarity determining region}, journal = {Chemical Communications}, year = 2021, } @article{CTT100858554, author = {Xuerao Ning and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of Fluorescent Immunosensor Quenchbody to Detect His-Tagged Recombinant Proteins Produced in Bioprocess}, journal = {Sensors}, year = 2021, } @article{CTT100858035, author = {T. Yasuda and A. Inoue and T. Kitaguchi and H. Ueda}, title = {Rapid construction of fluorescence quenching-based immunosensor Q-bodies using α-helical coiled-coil peptides}, journal = {Chemical Communications}, year = 2021, } @article{CTT100848804, author = {Y. Liang and Y. Wang and F. Wang and J. Li and C. Wang and J. Dong and H. Ueda and Z. Xiao and Y. Shen and Z. Xu and H. Wang}, title = {An Enhanced Open Sandwich Immunoassay by Molecular Evolution for Noncompetitive Detection of Alternaria Mycotoxin Tenuazonic Acid}, journal = {Food Chemistry}, year = 2021, } @article{CTT100848715, author = {Riho Takahashi and Takanobu Yasuda and Yuki Ohmuro-Matsuyama and Hiroshi Ueda}, title = {BRET Q‐Body: A Ratiometric Quench-based Bioluminescent Immunosensor Made of Luciferase−Dye−Antibody Fusion with Enhanced Response}, journal = {Analytical Chemistry}, year = 2021, } @article{CTT100847093, author = {Yuki Ohmuro-Matsuyama and Tetsuya Kitaguchi and Hiroshi Kimura and Hiroshi Ueda}, title = {Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies}, journal = {ACS Omega}, year = 2021, } @article{CTT100846219, author = {Hiroto Okuyama and Takanori Tamaki and Yuhei Oshiba and Hiroshi Ueda and Takeo Yamaguchi}, title = {Numerical Modeling for Sensitive and Rapid Molecular Detection by Membrane-Based Immunosensors}, journal = {Analytical Chemistry}, year = 2021, } @inproceedings{CTT100875217, author = {Ippei Tsujimura and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Development of an antibody-based red fluorescent probe and its characterization.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875222, author = {三田真理恵 and 菅原和 and 原田一貴 and 伊藤幹 and 滝澤舞 and 石田賢太郎 and 上田宏 and 北口哲也 and 坪井貴司}, title = {赤色蛍光タンパク質型グルコースセンサーの開発と糖代謝のライブセルイメージング}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875221, author = {本城麻衣 and 相原寛史 and Yanyan Hou and 上田宏 and 伊藤寿朗 and 北口哲也}, title = {抗体を分子認識ドメインとする蛍光タンパク質プローブを用いたジベレリンの定量}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875220, author = {Keisuke Yamashita and Ippei Tsujimura and Takashi Tsuboi and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Generation of a genetically-encoded IP3 biosensor based on a green fluorescent protein.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875223, author = {安田貴信 and 上野慶行 and 栃尾尚哉 and 八木宏昌 and 北口哲也 and 木川隆則 and 上田宏}, title = {NMRによる新規免疫センサーHibodyの抗原結合に伴う発光活性増大機構の解明}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875219, author = {Sohei Hiasa and Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi.}, title = {Development of green fluorescent protein-based indicators visualizing wide-range of cAMP dynamics for live-cell imaging.}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100875216, author = {飯島快斗 and 上野慶行 and 北口哲也 and 上田宏}, title = {発光タグ融合抗体結合タンパク質を用いた新規抗原検出系の構築}, booktitle = {第94回日本生化学会大会要旨集}, year = 2021, } @inproceedings{CTT100875215, author = {笹本佳那 and 安田貴信 and 北口哲也 and 上田宏}, title = {蛍光免疫センサープローブCoiled Q-probeを用いた各種低分子の検出と,FRET型プローブへの展開}, booktitle = {第94回日本生化学会大会要旨集}, year = 2021, } @inproceedings{CTT100875214, author = {安田貴信 and 井上暁人 and 北口哲也 and 上田宏}, title = {レシオ計測が可能な蛍光免疫センサーFRET Coiled Q-bodyにおけるDonor-Acceptor間距離の検討}, booktitle = {第94回日本生化学会大会要旨集}, year = 2021, } @inproceedings{CTT100864151, author = {大室有紀 and 古田忠臣 and 松井勇人 and 叶井正樹 and 上田宏}, title = {明るい小型発光酵素 "picALuc"}, booktitle = {}, year = 2021, } @inproceedings{CTT100875213, author = {Yancen Dai and Atsushi Izutani and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Intracellular detection of tumor suppressor protein p53 by Q-body technology}, booktitle = {第 73回日本生物工学会大会要旨集}, year = 2021, } @inproceedings{CTT100875212, author = {井上暁人 and 安田貴信 and 北口哲也 and 村上 明一 and 上田宏}, title = {酵母提示系を用いたナノ抗体由来の蛍光免疫センサ“mini Q-body”選択法の開発}, booktitle = {第 73回日本生物工学会大会要旨集}, year = 2021, } @inproceedings{CTT100875157, author = {パクジュンテ and 有坂亮汰 and 柴田貴広 and 内田浩二 and 董金華 and 北口哲也 and 上田宏}, title = {ゲノム編集法によるオープンサンドイッチ免疫測定用抗体の産生}, booktitle = {化学工学会第52回秋季大会要旨集}, year = 2021, } @inproceedings{CTT100875144, author = {Akihito Inoue and Yuki Ohmuro and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of mini Q-body using the nanobody to detect chemotherapy agent.}, booktitle = {}, year = 2021, } @inproceedings{CTT100875155, author = {井上暁人 and 安田貴信 and 北口哲也 and 村上 明一 and 上田宏}, title = {酵母細胞表層提示系を用いた抗ヒト血清アルブミン (HSA)ナノ抗体由来“mini Q-body”の選択}, booktitle = {化学工学会第52回秋季大会要旨集}, year = 2021, } @inproceedings{CTT100875159, author = {朱博 and 董金華 and 寧雪じょう and 井上暁人 and 北口哲也 and 上田宏}, title = {Quenchbodyを用いた1分間SARS-CoV-2及び変異株の検出法}, booktitle = {化学工学会第52回秋季大会要旨集}, year = 2021, } @inproceedings{CTT100875140, author = {Hiroshi Ueda and Jinhua Dong and Takanobu Yasuda and Masaki Takahashi and Kana Sasamoto and Hiroyuki Oyama and Izumi Morita and Hee-Jin Jeong and Tetsuya Kitaguchi and Norihiro Kobayashi.}, title = {PM Q-probe: a fluorescent binding protein that converts many antibodies to a fluorescent biosensor.}, booktitle = {}, year = 2021, } @inproceedings{CTT100875142, author = {Akihito Inoue and Yuki Ohmuro and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of mini Q-body using the nanobody to detect chemotherapy agent.}, booktitle = {}, year = 2021, } @inproceedings{CTT100854299, author = {Yuki Ohmuro and Tadaomi Furuta and Hayato Matsui and Masaki Kanai and Hiroshi Ueda}, title = {Development of the smallest luciferase “picALuc” among bright-light emitting luciferases}, booktitle = {}, year = 2021, } @inproceedings{CTT100875130, author = {上田宏 and 有坂亮汰 and 朴俊泰 and 董金華 and 柴田貴広 and 大室有紀 and 北口哲也 and 内田浩二}, title = {ゲノム編集法による酸化脂質類の非競合的免疫測定系の構築}, booktitle = {第74回日本酸化ストレス学会・第21回日本NO学会 合同学術集会要旨集}, year = 2021, } @inproceedings{CTT100854631, author = {笹本佳那 and 安田貴信 and 北口哲也 and 上田宏}, title = {迅速簡便に高性能な蛍光免疫センサーを構築可能なCoiled Q-probeの創出}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854637, author = {Marie Mita and Mai Takizawa and Rei Nagata and Kazuki Harada and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Sucralose activates intracellular Ca2+ and cAMP signaling in enteroendocrine L cells.}, booktitle = {第98回日本生理学会大会要旨集}, year = 2021, } @inproceedings{CTT100854635, author = {Zhu Bo and Dong Jinhua and Xuerao Ning and Akihito Inoue and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Development of quenchbody-based 1-minute SARS-CoV-2 detection assay.}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854634, author = {Xuerao Ning and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Construction of fluorescent biosensor Q-body for detecting recombinant proteins produced in bioprocess}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854633, author = {Yancen Dai and Atsushi Izutani and Takanobu Yasuda and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Instant detection of tumor suppressor protein p53 by Q-body technology.}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @inproceedings{CTT100854632, author = {Junqian Wang and Tetsuya Kitaguchi and Hiroshi Ueda}, title = {Development of a novel immunosensor system based on antigen-dependent assembly of fluorescent proteins.}, booktitle = {化学工学会第86年会要旨集}, year = 2021, } @misc{CTT100875117, author = {Akihito Inoue and Takanobu Yasuda and Bo Zhu and Tetsuya Kitaguchi and Akikazu Murakami and Hiroshi Ueda.}, title = {Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface.}, year = 2021, } @misc{CTT100848806, author = {Hiroshi Ueda and Jinhua Dong}, title = {Biosensors: Homogeneous Detection}, year = 2021, } @misc{CTT100861308, author = {上田 宏}, title = {抗体関連タンパク質の蛍光修飾によるバイオセンサー化}, year = 2021, } @misc{CTT100843715, author = {Jinhua Dong and Hiroshi Ueda}, title = {Recent Advances in Quenchbody, a Fluorescent Immunosensor}, year = 2021, } @misc{CTT100865567, author = {上田宏 and 綱 美香  and 原田 義孝 }, title = {低分子化合物の簡易検出法}, howpublished = {公開特許}, year = 2021, month = {}, note = {特願2020-056188(2020/03/26), 特開2021-156695(2021/10/07)} } @misc{CTT100864142, author = {佐藤伸一 and 中村浩之 and 上田宏}, title = {蛍光標識抗体又は抗体断片}, howpublished = {公開特許}, year = 2021, month = {}, note = {特願2020-534145(2019/07/10), 再表2020/026733(2021/08/19)} } @misc{CTT100820743, author = {上田宏 and 大室有紀 and 三宅千絢 and 塚原知也}, title = {抗原検出又は測定用キット}, howpublished = {登録特許}, year = 2021, month = {}, note = {特願2018-566814(2018/01/17), 再表2018-147018(2019/12/12), 特許第6983419号(2021/11/26)} } @misc{CTT100789767, author = {上田宏 and 董金華}, title = {融合タンパク質及びそれを用いた抗原の検出方法}, howpublished = {登録特許}, year = 2021, month = {}, note = {特願2017-563741(2016/12/21), 再表2017/130610(2018/11/15), 特許第6873483号(2021/04/23)} }