@article{CTT100882626, author = {B. Zhu and N. Nosaka and S. Kanamaru and J. Dong and Y. Dai and A. Inoue and Y. Yang and K. Kobayashi and T. Kitaguchi and H. Iwasaki and R. Koike and K. Wakabayashi and H. Ueda}, title = {Rapid and sensitive SARS-CoV-2 detection using a homogeneous fluorescent immunosensor Quenchbody with crowding agents}, journal = {Analyst}, year = 2022, } @article{CTT100882627, author = {Jiulong Su and Bo Zhu and Akihito Inoue and Hiroyuki Oyama and Izumi Morita and Jinhua Dong and Takanobu Yasuda and Yoshiko Sugita-Konishi and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake and Hiroshi Ueda}, title = {The Patrol Yeast: a new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning}, journal = {Biosensors and Bioelectronics}, year = 2022, } @article{CTT100882135, author = {Haimei Li and Bo Zhu and Baowei Li and Limei Chen and Xuerao Ning and Hang Dong and Jingru Liang and Xueying Yang and Jinhua Dong and Hiroshi Ueda}, title = {Isolation of a human SARS-CoV-2 neutralizing antibody from a synthetic phage library and its conversion to fluorescent biosensors}, journal = {Scientific Reports}, year = 2022, } @article{CTT100899545, author = {Mai Takizawa and Yuri Osuga and Rika Ishida and Marie Mita and Kazuki Harada and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging.}, journal = {Commun Biol}, year = 2022, } @article{CTT100880996, author = {Yancen Dai and Yuko Sato and Bo Zhu and Tetsuya Kitaguchi and Hiroshi Kimura and Farid J. Ghadess and Hiroshi Ueda}, title = {Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting}, journal = {Chemical Science}, year = 2022, } @article{CTT100877419, author = {I. Morita and Y. Kiguchi and H. Oyama and K. Yamaki and N. Sakio and Keisuke Kashiwabara and Y. Kuroda and A. Ito and A. Yokota and N. Ikeda and A. Takeuchi and C. Tode and H. Ueda and S. Numazawa and R. Kikura-Hanajiri and T. Yoshida and N. Kobayashi}, title = {Derivatization-assisted immunoassays: application for group-specific detection of potent methamphetamine and amphetamine enantiomers}, journal = {Analytical Methods}, year = 2022, } @article{CTT100877425, author = {H.-O. Yun and H. Ueda and H.-J. Jeong}, title = {Development of a spacer-optimized Quenchbody against tumor necrosis factor alpha}, journal = {Biotechnology annd Bioprocess Engineering}, year = 2022, } @article{CTT100869186, author = {J. Liang and H. Dong and H. Wang and G. Jiang and T. Inagaki and C.E. Gomez-Sanchez and J. Liang and H. Dong and H. Wang and Z. Yi and G. Jiang and T. Inagaki and C.E. Gomez-Sanchez and J. Dong* and H. Ueda*}, title = {Creation of a Quick and Sensitive Fluorescent Immunosensor for Detecting the Mineralocorticoid Steroid Hormone Aldosterone}, journal = {Journal of Steroid Biochemistry and Molecular Biology}, year = 2022, } @article{CTT100867224, author = {Yuki Ohmuro-Matsuyama and Tadaomi Furuta and Hayato Matsui and Masaki Kanai and Hiroshi Ueda}, title = {Miniaturization of bright light-emitting luciferase ALuc: picALuc}, journal = {ACS Chem. Biol.}, year = 2022, } @article{CTT100875114, author = {Marie Mita and Izumi Sugawara and Kazuki Harada and Motoki Ito and Mai Takizawa and Kentaro Ishida and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics}, journal = {Cell Chem Biol}, year = 2022, } @inproceedings{CTT100899577, author = {笹本佳那 and 安田貴信 and 北口哲也 and 上田宏}, title = {逆並行結合抑制型ペプチドペアによる抗体を蛍光免疫センサに変換するプローブタンパク質Coiled Q-probeの蛍光応答向上}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100899576, author = {井上暁人 and 安田貴信 and 北口哲也 and 村上明一 and 上田宏}, title = {酵母提示系によるナノ抗体由来の蛍光免疫センサnano Q-bodyの分子進化法の開発}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100899579, author = {Keisuke Yamashita and Takashi Tsuboi and Hiroshi Ueda and Tetsuya Kitaguchi.}, title = {Development of a GFP-based biosensor for visualizing intracellular IP3 dynamics}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100887853, author = {塘 知子 and 朱 博 and 北口 哲也 and 上田 宏}, title = {蛍光免疫センサーQuenchbodyのシグナル増幅と高速スクリーニング法の探索}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100899578, author = {日浅 綜平 and 藤森 武流 and Saki Aiki and 上田 宏 and Takashi Tsuboi and 北口 哲也}, title = {幅広い濃度範囲の検出を可能とする複数の緑色蛍光cAMPセンサーの開発}, booktitle = {第45回日本分子生物学会年会要旨集}, year = 2022, } @inproceedings{CTT100883091, author = {大室(松山)有紀 and 古田忠臣 and 松井勇人 and 叶井正樹 and 上田宏}, title = {最小サイズの発光酵素「picALuc」の開発とその応用}, booktitle = {}, year = 2022, } @inproceedings{CTT100899575, author = {伊藤良浩 and 佐々木隆一 and 朝里さやか and 北口哲也 and 上田 宏}, title = {微小ドロップレット培養とバイオセンサーを用いたタンパク質高生産株スクリーニング法の開発}, booktitle = {第74回日本生物工学会大会要旨集}, year = 2022, } @inproceedings{CTT100899571, author = {Hiroshi Ueda and Bo Zhu and Jiulong Su and Tetsuya Kitaguchi and Norihiro Kobayashi and Shiro Miyake.}, title = {Development of “patrol yeasts” for the detection of multiple toxic substances in foods}, booktitle = {The 15th Asian Congress on Biotechnology}, year = 2022, } @inproceedings{CTT100899561, author = {上田宏 and 蘇九龍 and 朱博 and 井上暁人 and 大山浩之 and 森田いずみ and 董金華 and 小西良子 and 北口哲也 and 小林典裕 and 三宅司郎}, title = {各種食中毒から生活者を守る「パトロール酵母」の開発}, booktitle = {第74回日本生物工学会大会要旨集}, year = 2022, } @inproceedings{CTT100887888, author = {Hiroshi Ueda and Bo Zhu and Jinhua Dong}, title = {Isolation of recombinant human antibody for the prevention and rapid diagnosis of COVID-19}, booktitle = {}, year = 2022, } @inproceedings{CTT100900707, author = {安田貴信 and 笹本佳那 and 北口哲也 and 上田宏}, title = {逆平行結合抑制ペプチドペアを用いたクエンチ抗体の構築と評価}, booktitle = {第16回バイオ関連化学シンポジウム要旨集}, year = 2022, } @inproceedings{CTT100887859, author = {朱博 and 野坂 宜之 and 董 金華 and 北口 哲也 and 小池 竜 司 and 若林 健二 and 上田 宏}, title = {Converting antibodies to rapid response SARS-CoV-2 homogeneous immunosensors via Quenchbody technology and crowding agent}, booktitle = {化学工学会第53 回秋季大会要旨集}, year = 2022, } @inproceedings{CTT100887890, author = {井上暁人 and 鈴木大凱 and YANG Yinghui and 安田貴信 and 朱博 and 北口哲也 and 上田宏}, title = {コルチゾール認識ナノ抗体の蛍光免疫センサー化}, booktitle = {第16回バイオ関連化学シンポジウム要旨集}, year = 2022, } @inproceedings{CTT100899573, author = {倉田晴生 and 安田貴信 and 北口哲也 and 上田宏}, title = {発光タグを付加したペプチドを用いた免疫センサーの構築}, booktitle = {化学工学会第53 回秋季大会要旨集}, year = 2022, } @inproceedings{CTT100887854, author = {Dai Yancen and Sato Yuko and Zhu Bo and Kitaguchi Tetsuya and Kimura Hiroshi and Farid J. Ghadessy and Ueda Hiroshi}, title = {Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live-cell imaging and sorting}, booktitle = {Bioanalytical Sensors Gordon Research Conference}, year = 2022, } @inproceedings{CTT100877602, author = {Bo Zhu and Haimei Li and Yancen Dai and Akihito Inoue and Yinghui Yang and Kaori Kobayashi and Tetsuya Kitaguchi and Jinhua Dong and Hiroshi Ueda}, title = {Rapid construction of homogeneous immunosensors for SARS-CoV-2 nucleocapsid and spike proteins using Quenchbody and Quenchprobe technology}, booktitle = {Bioanalytical Sensors Gordon Research Conference}, year = 2022, } @inproceedings{CTT100869546, author = {大室有紀 and 古田忠臣 and 松井勇人 and 叶井正樹 and 上田宏}, title = {発光酵素の特性を利用したタンパク質間相互作用検出系、及び新規小型発光酵素の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100875230, author = {小林香央里 and 朱博 and 北口哲也 and 上田宏}, title = {蛍光免疫プローブQuenchprobeのダブルラベル化の検討}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875234, author = {Yanmin Chen and Yancen Dai and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Development of a multicolor Q-body construction method using Escherichia coli.}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875232, author = {椿凜果 and 安田貴信 and 朱博 and 北口哲也 and 上田宏}, title = {蛍光免疫センサーCoiled Quenchbodyのがん光線力学療法への応用}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875235, author = {Yancen Dai and Bo Zhu and Yuko Sato and Hiroshi Kimura and Farid J. Ghadessy and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Development of an immunofluorescence probe Q-body for the direct visualization of tumor marker p53 in fixed and living cells.}, booktitle = {化学工学会第87年会要旨集}, year = 2022, } @inproceedings{CTT100875227, author = {Marie Mita and Izumi Sugawara and Kazuki Harada and Motoki Ito and Mai Takizawa and Kentaro Ishida and Hiroshi Ueda and Tetsuya Kitaguchi and Takashi Tsuboi.}, title = {Visualization of intracellular glucose metabolism dynamics by red fluorescent protein-based glucose indicators.}, booktitle = {第99回日本生理学会大会要旨集}, year = 2022, } @misc{CTT100899553, author = {伊藤良浩 and 佐々木隆一 and 朝里さやか and 北口哲也 and 上田 宏}, title = {微小ドロップレット培養とバイオセンサーを用いたタンパク質高生産株スクリーニング法の開発}, year = 2022, } @misc{CTT100899552, author = {Sohei Hiasa and Takeru Fujimori and Saki Aiki and Hiroshi Ueda and Takashi Tsuboi and Tetsuya Kitaguchi}, title = {Development of green fluorescent protein-based cAMP indicators with expanded dynamic range and various working ranges}, year = 2022, } @misc{CTT100899550, author = {Bo Zhu and Cheng Qian and Haoxuan Tang and Tetsuya Kitaguchi and Hiroshi Ueda.}, title = {Creating a thermostable beta-glucuronidase switch for homogeneous immunoassay by disruption of conserved salt bridges at diagonal interfaces}, year = 2022, } @misc{CTT100877445, author = {上田宏 and 北口哲也 and SuJiulong and 三宅 司郎  and 小林 典裕 }, title = {抗体断片を含む人工受容体を細胞膜に提示した酵母とこれを用いた抗原検出法 }, howpublished = {公開特許}, year = 2022, month = {}, note = {特願2020-145870(2020/08/31), 特開2022-040923(2022/03/11)} } @misc{CTT100831058, author = {上田宏 and SuJiulong and 北口哲也 and 大室有紀 and Shawn Hoon and Cyrus Beh }, title = {バイオセンサー}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2018-207624(2018/11/02), 特開2020-068746(2020/05/07), 特許第7169582号(2022/11/02)} }