Single-motor mechanics and models of the myosin motor
Author
Japanese:
T. Yanagida,
S. Esaki,
A. Hikikoshi Iwane,
Y. Inoue,
A. Ishijima,
K. Kitamura,
H. Tanaka,
徳永 万喜洋.
English:
T. Yanagida,
S. Esaki,
A. Hikikoshi Iwane,
Y. Inoue,
A. Ishijima,
K. Kitamura,
H. Tanaka,
M. Tokunaga.
Language
English
Journal/Book name
Japanese:
English:
Phil. Trans. R. Soc. Lond. B
Volume, Number, Page
Vol. 355
No. 1396
pp. 441-447
Published date
Apr. 2000
Publisher
Japanese:
English:
THE ROYAL SOCIETY
Conference name
Japanese:
English:
Conference site
Japanese:
English:
Abstract
Recent progress in single-molecule detection techniques is remarkable. These techniques have allowed the accurate determination of myosin-head-induced displacements and how mechanical cycles are coupled to ATP hydrolysis, by measuring individual mechanical events and chemical events of actomyosin directly at the single-molecule level. Here we review our recent work in which we have made detailed measurements of myosin step size and mechanochemical coupling, and propose a model of the myosin motor.