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Title
Japanese:Rhodium- and Iridium-Catalyzed Dehydrogenative Cyclization through Double C-H Bond Cleavages To Produce Fluorene Derivatives. 
English:Rhodium- and Iridium-Catalyzed Dehydrogenative Cyclization through Double C-H Bond Cleavages To Produce Fluorene Derivatives. 
Author
Japanese: Masaki Itoh, Koji Hirano, Tetsuya Satoh, Yu Shibata, 田中健, Masahiro. Miura.  
English: Masaki Itoh, Koji Hirano, Tetsuya Satoh, Yu Shibata, Ken Tanaka, Masahiro. Miura.  
Language English 
Journal/Book name
Japanese:Journal of Organic Chemistry 
English:Journal of Organic Chemistry 
Volume, Number, Page Vol. 78    No. 4    pp. 1365-1370
Published date Jan. 29, 2013 
Publisher
Japanese:American Chemical Society 
English:American Chemical Society 
Conference name
Japanese: 
English: 
Conference site
Japanese: 
English: 
DOI https://doi.org/10.1021/jo4000465
Abstract The rhodium-catalyzed cyclization of a series of 2,2-diarylalkanoic acids in the presence of copper acetate as an oxidant smoothly proceeded through double C-H bond cleavages and subsequent decarboxylation to produce the corresponding fluorene derivs. E.g., in presence of [CpERhCl2]2 [CpE = 1,3-bis(ethoxycarbonyl)-2,4,5-trimethylcyclopentadienyl] and Cu(OAc)2, dehydrogenative cyclization of 2,2-diphenylpropanoic acid gave 65% 9-methylfluorene. The direct cyclization of triarylmethanols also took place efficiently by using an iridium catalyst in place of the rhodium, while the hydroxy function was still intact. [on SciFinder(R)]

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