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Title
Japanese:3P2-G05 抗がん剤スクリーニングのためのがん細胞分散MEMSデバイス(ナノ・マイクロ流体システム) 
English: 
Author
Japanese: 神永 真帆, 石田 忠, 門之園 哲哉, 近藤 科江, 小俣 透.  
English: 神永 真帆, 石田 忠, 門之園 哲哉, Shinae Kizaka-Kondoh, 小俣 透.  
Language Japanese 
Journal/Book name
Japanese:ロボティクス・メカトロニクス講演会講演概要集 
English: 
Volume, Number, Page Vol. 2014       
Published date Apr. 2014 
Publisher
Japanese:一般社団法人日本機械学会 
English: 
Conference name
Japanese: 
English: 
Conference site
Japanese: 
English: 
Abstract Cancer is the top leading cause of death in Japan. Anti-cancer drugs are one of the most popular treatments whereas they often have heavy side effects. Anti-cancer drugs with light or no side effects are under development using tumor specific binding peptides as guides to cancer cells. However, the number of candidate peptides for the tumor specific binding peptides are extremely large. An efficient peptide screening method is necessary to find them. For this purpose, we are developing a microfluidic device to uniformly disperse cancer cells into its micro chamber and screen the peptide form the large number of peptides. In this paper, we could uniformly disperse N87 cells into the micro chamber using a micro pillar array, and selectively trap yeasts with tumor specific binding peptides by N87 cells in the micro chamber.

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