Home >

news Help

Publication Information


Title
Japanese:Synthesis of 2-Indolyltetrahydroquinolines by Zinc (II)-Catalyzed Intramolecular Hydroarylation-Redox Cross-Dehydrogenative Coupling of N-Propargylanilines with Indoles 
English:Synthesis of 2-Indolyltetrahydroquinolines by Zinc (II)-Catalyzed Intramolecular Hydroarylation-Redox Cross-Dehydrogenative Coupling of N-Propargylanilines with Indoles 
Author
Japanese: 李 廣哲, 中村 浩之.  
English: Guangzhe Li, Hiroyuki Nakamura.  
Language English 
Journal/Book name
Japanese:Angewandte Chemie International Edition 
English:Angewandte Chemie International Edition 
Volume, Number, Page Vol. 55    No. 23    pp. 6758-6761
Published date Apr. 21, 2016 
Publisher
Japanese: 
English: 
Conference name
Japanese: 
English: 
Conference site
Japanese: 
English: 
DOI https://doi.org/10.1002/anie.201602416
Abstract An intramolecular hydroarylation-redox-cross dehydrogenative coupling (CDC) of propargylic anilines with indoles proceeded in the presence of zinc(II) catalysts to give 2-indolyltetrahydroquinolines in good to high yields. Three C-H bonds (two sp2 and one sp3) are activated in one shot and these hydrogen atoms are trapped by a propargylic triple bond in the molecule.

©2007 Tokyo Institute of Technology All rights reserved.