Single-motor mechanics and models of the myosin motor
著者
和文:
T. Yanagida,
S. Esaki,
A. Hikikoshi Iwane,
Y. Inoue,
A. Ishijima,
K. Kitamura,
H. Tanaka,
徳永 万喜洋.
英文:
T. Yanagida,
S. Esaki,
A. Hikikoshi Iwane,
Y. Inoue,
A. Ishijima,
K. Kitamura,
H. Tanaka,
M. Tokunaga.
言語
English
掲載誌/書名
和文:
英文:
Phil. Trans. R. Soc. Lond. B
巻, 号, ページ
Vol. 355
No. 1396
pp. 441-447
出版年月
2000年4月
出版者
和文:
英文:
THE ROYAL SOCIETY
会議名称
和文:
英文:
開催地
和文:
英文:
アブストラクト
Recent progress in single-molecule detection techniques is remarkable. These techniques have allowed the accurate determination of myosin-head-induced displacements and how mechanical cycles are coupled to ATP hydrolysis, by measuring individual mechanical events and chemical events of actomyosin directly at the single-molecule level. Here we review our recent work in which we have made detailed measurements of myosin step size and mechanochemical coupling, and propose a model of the myosin motor.