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タイトル
和文: 
英文:Prediction of flux declined in ultrafiltration of protein solution considering pore blockage and compressible cake layer model 
著者
和文: NGUYEN TUAN ANH, 吉川史郎, 大川原真一.  
英文: Tuan-Anh Nguyen, SHIRO YOSHIKAWA, Shinichi OOKAWARA.  
言語 English 
掲載誌/書名
和文: 
英文:Proceedings of International Workshop on Process Intensification 2012 
巻, 号, ページ        
出版年月 2012年11月8日 
出版者
和文: 
英文: 
会議名称
和文: 
英文:International Workshop on Process Intensification 2012 
開催地
和文:ソウル 
英文:Seoul 
アブストラクト Ultrafiltration of macromolecular solutions has increasingly become an important separation process. In such processes, the critical problem is the decline of permeate flux caused by membrane fouling. In this study, a simple model which combines pore blockage and compressible cake layer is proposed to describe the behavior of filtrate flux during filtration. In the model, it is considered that membrane fouling by pore blockage mechanism and the development of compressible cake layer occur simultaneously. The pore blockage model and compressive yield stress model are modified and coupled to give the numerical prediction of the permeate flux. In addition, the steady state permeate flux, which is difficult to obtain in ultrafiltration processes due to long time operation requirement, can be estimated directly from the model. The cross-flow ultrafiltration system (MWCO 5000) of the protein solution was used for the validation of the model. In experiments, the trans-membrane pressures and the feed flow rates were varied while the temperature and the protein concentration were kept at constant. The comparison results indicate that entire permeation process is well presented by the proposed combined model. It also suggested that the importance factor affect the steady state permeate flux is the feed flow rate.

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