Recently, it has been equipped with damping devises for improving the seismic resistant performance in case of long-period grand motion caused by huge earthquake. The purpose of this study is to examine the effects of response reduction and energy absorption capacity in case that the hysteresis dampers are partially-installed in the high-rise building subjected to long-period ground motion having the specific period rang. The analyses results show that the response characteristics of the 40% partially-installing system are almost same as the full installed damper system. In addition, real-scale experiments are carried out in E-Defense, energy distributions and response decreases are evaluated