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Publication List - Takahiro Nomoto (235 entries)
Journal Paper
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Keitaro Homma,
Y. Miura*,
M. Kobayashi,
W. Chintrakulchai,
M. Toyoda,
K. Ogi,
J. Michinishi,
T. Ohtake,
Y. Honda,
T. Nomoto,
H. Takemoto,
N. Nishiyama.
Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential,
Sci. Technol. Adv. Mater.,
Vol. 25,
No. 1,
pp. 233878,
Apr. 2024.
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Shan Gao,
Y. Miura,
A. Sumiyoshi,
S. Ohno,
K. Ogata,
T. Nomoto,
M. Matsui,
Y. Honda,
M. Suzuki,
M. Iiyama,
K. Osada,
I. Aoki,
N. Nishiyama.
Self-folding macromolecular drug carrier for cancer imaging and therapy,
Advanced Science,
Vol. 11,
No. 7,
pp. e2304171,
Nov. 2023.
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Y. Hattori,
T. Andoh,
S. Kawabata,
N. Hu,
H. Michiue,
H. Nakamura,
T. Nomoto,
M. Suzuki,
T. Takata,
H. Tanaka,
T. Watanabe,
K. Ono.
Proposal of recommended experimental protocols for in vitro and in vivo evaluation methods of boron agents for neutron capture therapy,
Journal of Radiation Research,
vol. 64,
No. 6,
p. 859,
Nov. 2023.
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Xin Shen,
A. Dirisala,
M. Toyoda,
Yao Xiao,
H. Guo,
Y. Honda,
T. Nomoto,
H. Takemoto,
Y. Miura,
N. Nishiyama.
pH-Responsive polyzwitterion covered nanocarriers for DNA delivery,
J. Control. Release,
Vol. 360,
pp. 928-939,
July 2023.
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Haochen Guo,
Xu Wen,
Takahiro Nomoto,
Kaito Kanamori,
Yan Ming Voon,
Yuto Honda,
Naoki Yamada,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters.,
Biomaterials,
Vol. 293,
pp. 121987,
Feb. 2023.
Official location
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Takahiro Nomoto,
Kana Komoto,
Tomoya Nagano,
Takuya Ishii,
Haochen Guo,
Yuto Honda,
Shun-ichiro OGURA,
Masahiro Ishizuka,
Nobuhiro Nishiyama.
Polymeric iron chelators for enhancing 5-aminolevulinic acid-induced photodynamic therapy,
Cancer Sci.,
Vol. 114,
No. 3,
pp. 1086-1094,
Nov. 2022.
Official location
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Yuto Honda,
Sayaka Onodera,
Hiroyasu Takemoto,
Faizah Noor,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Yudi Sun,
Yutaka Miura,
Nobuhiro Nishiyama.
Thermo-responsive polymer-siRNA conjugates enabling artificial control of gene silencing around body temperature,
Pharmaceutical Research,
Vol. 40,
No. 1,
pp. 157-165,
Oct. 2022.
Official location
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Yijung Sung,
Haochen Guo,
Aria Ghasemizadeh,
Xin Shen,
Wanphiwat Chintrakulchai,
Motoaki Kobayashi,
Masahiro Toyoda,
Koichi Ogi,
Junya Michinishi,
Tokoyuki Ohtake,
Makoto Matsui,
Yuto Honda,
Takahiro Nomoto,
Hiroyasu Takemoto,
Yutaka Miura,
Nobuhiro Nishiyama.
Cancerous pH-responsive polycarboxybetaine-coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model,
Cancer Science,
Vol. 113,
No. 12,
pp. 4339-4349,
Oct. 2022.
Official location
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Xue Xie,
Yuta Kurashina,
Makoto Matsui,
Takahiro Nomoto,
Munenari Itoh,
Hirotaka J Okano,
Kentaro Nakamura,
Nobuhiro Nishiyama,
Yoshitaka Kitamoto.
Transdermal delivery of bFGF with sonophoresis facilitated by chitosan nanocarriers,
Elsevier,
vol. 75,
103675,
Sept. 2022.
Official location
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Aziz Awaad,
Hiroyasu Takemoto,
Muneaki Iizuka,
Koichi Ogi,
Yuki Mochida,
Abdul-Hackam Ranneh,
Masahiro Toyoda,
Makoto Matsui,
Takahiro Nomoto,
Yuto Honda,
Kotaro Hayashi,
Keishiro Tomoda,
Tomoyuki Ohtake,
Yutaka Miura,
Nobuhiro Nishiyama.
Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration,
Journal of Controlled Release,
Vol. 346,
pp. 392-404,
May 2022.
Official location
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Yuta Kurashina,
Risa Asano,
Makoto Matsui,
Takahiro Nomoto,
Keita Ando,
Kentaro Nakamura,
Nobuhiro Nishiyama,
Yoshitaka Kitamoto.
Quantitative analysis of acoustic pressure for sonophoresis and its effect on transdermal penetration,
Feb. 2022.
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Guo H.,
Nomoto T.,
Muttaqien S.E.,
Sun X.,
Komoto K.,
Matsui M.,
Miura Y.,
Nishiyama N..
A polymeric iron chelator enhancing pro-oxidant antitumor efficacy of vitamin C by inhibiting extracellular Fenton reaction,
Molecular Pharmaceutics,
Vol. 18,
Issue 12,
Dec. 2021.
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Yuto Honda*,
Takahiro Nomoto,
Makoto Matsui,
Hiroyasu Takemoto,
Yutaka Miura,
Nobuhiro Nishiyama*.
Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity,
ACS Applied Materials and Interfaces,
Vol. 13,
No. 46,
pp. 54850–54859,
Nov. 2021.
Official location
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Yuto Honda*,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Kaori Taniwaki,
Haochen Guo,
Yutaka Miura,
Nobuhiro Nishiyama*.
Systemically Applicable Glutamine-Functionalized Polymer Exerting Multivalent Interaction with Tumors Overexpressing ASCT2.,
ACS Applied Bio Materials,
Vol. 4,
No. 10,
pp. 7402–7407,
Aug. 2021.
Official location
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Yuma Ikeda,
Mariko Orioka,
Takahiro Nomoto,
Yuki Hiruma,
Nobuhiro Nishiyama,
Daniel Citterio.
Differentialeffect of azetidine substitution in firefly luciferin analogues,
ChemBioChem,
Vol. 22,
No. 21,
pp. 3067-3074,
Aug. 2021.
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Masayoshi Tanaka,
Mirei Hayashi,
Roach Lucien,
Yuka Kiriki,
Tetsuya Kadonosono,
Takahiro Nomoto,
Nobuhiro Nishiyama,
Choi Jonghoon,
Critchley Kevin,
D. Evans Stephen,
Mina Okochi.
Synthesis of near-infrared absorbing triangular Au nanoplates using biomineralisation peptides,
ACTA Biomaterialia,
June 2021.
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Takahiro Nomoto,
Ying Yao,
Yukiya Inoue,
Minoru Suzuki,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy,
Journal of Controlled Release,
Vol. 332,
pp. 184-193,
Feb. 2021.
Official location
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Komoto Kana,
Takahiro Nomoto,
Muttaqien S.,
Takemoto Hiroyasu,
Matsui Makoto,
Miura Yutaka,
Nishiyama Nobuhiro.
Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine,
Cancer Science,
Vol. 112,
No. 1,
pp. 410-421,
Jan. 2021.
Official location
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S Muttaqien,
Takahiro Nomoto,
Xuebo Dou,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
Photodynamic therapy using LCST polymers exerting pH-responsive isothermal phase transition,
Journal of Controlled Release,
Vol. 328,
pp. 608-616,
Dec. 2020.
Official location
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Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Hiroyasu Takemoto,
Yuka Kaihara,
Yutaka Miura,
Nobuhiro Nishiyama.
Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery,
Biomacromolecules,
Vol. 21,
No. 9,
pp. 3826-3835,
Sept. 2020.
Official location
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Xiaohang Sun,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Haochen Guo,
Yudi Sun,
Yutaka Miura,
Nobuhiro Nishiyama.
Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives,
Journal of Controlled Release,
Sept. 2020.
Official location
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Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
M Suzuki,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism,
Science Advances,
Vol. 6,
No. 4,
Jan. 2020.
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Yuma Ikeda,
Takahiro Nomoto,
Yuki Hiruta,
Nobuhiro Nishiyama,
Daniel Citterio.
Ring-Fused Firefly Luciferins: Expanded Palette of Near-Infrared Emitting Bioluminescent Substrates,
Analytical Chemistry,
Vol. 92,
No. 6,
pp. 4235-4243,
2020.
Official location
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Hiroyasu Takemoto,
Takanori Inaba,
Takahiro Nomoto,
Makoto Matsui,
Gyomon Ryu,
Masahiro Toyoda,
Yuto Honda,
Kaori Taniwaki,
Naoki Yamada,
Junhyun Kim,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects,
Biomaterials,
Vol. 235,
2020.
Official location
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Hiroyasu Takemoto,
Wang, Chih-Ling,
Takahiro Nomoto,
Matsui, Makoto,
Tomoda, Keishiro,
Nobuhiro Nishiyama.
Pyruvate responsiveness based on α-oxohydrazone formation for intracellular siRNA release from polyion complex-based carriers,
Biomacromolecules,
May 2019.
Official location
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Watanabe, Sumiyo,
Hayashi, Kotaro,
Toh, Kazuko,
Kim Hyun Jin,
Liu, Xueying,
Chaya, Hiroyuki,
Fukushima, Shigeto,
Katsushima, Keisuke,
Kondo, Yutaka,
Uchida, Satoshi,
Ogura, Satomi,
Takahiro Nomoto,
Hiroyasu Takemoto,
Cabral, Horacio,
Kinoh, Hiroaki,
Tanaka, Hiroyoshi,
Kano, Mitsunobu,
Matsumoto, Yu,
Fukuhama, Hiroshi,
Uchida, Shyunya,
Nagaku, Masaomi,
Osada, Kensuke,
Nobuhiro Nishiyama,
Miyata, Kanjiro,
Kataoka, Kazunori.
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers,
Nature Communications,
Apr. 2019.
Official location
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Muttaqien,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety,
BIOMACROMOLECULES,
Vol. 20,
No. 4,
pp. 1493-1504,
Dec. 2018.
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Tsukasa Chida,
Yutaka Miura,
Cabral Horacio,
Takahiro Nomoto,
Kazunori Kataoka,
Nobuhiro Nishiyama.
Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release,
J. Control. Release,
Vol. 292,
pp. 130-140,
Dec. 2018.
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X. Dou,
T. Nomoto,
H. Takemoto,
M. Matsui,
K. Tomoda,
N. Nishiyama.
Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers,
Scientific Reports,
Vol. 8,
No. 1,
pp. 8126,
May 2018.
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A.-H. Ranneh,
H. Takemoto,
S. Sakuma,
A. Awaad,
T. Nomoto,
Y. Mochida,
M. Matsui,
K. Tomoda,
M. Naito,
N. Nishiyama.
An ethylenediamine-based switch to control the polyzwitterion charge at tumorous pH for effective tumor accumulation of coated nanomaterials,
Angewandte Chemie International Edition,
Vol. 57,
No. 18,
pp. 5057,
Apr. 2018.
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N. Yamada,
Y. Honda,
H. Takemoto,
T. Nomoto,
M. Matsui,
K. Tomoda,
M. Konno,
H. Ishii,
M. Mori,
N. Nishiyama.
Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism,
Scientific Reports,
Vol. 7,
No. 1,
pp. 6077,
July 2017.
Official location
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Chih-Hao Huang,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
Utility of 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-conjugated Polymer System,
ChemMedChem,
Vol. 12,
No. 1,
pp. 19-22,
Jan. 2017.
Official location
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Qixian Chen,
Kensuke Osada,
Zhishen Ge,
Satoshi Uchida,
Theofilus A. Tockary,
Anjaneyulu Dirisala,
Akitsugu Matsui,
Kazuko Toh,
Kaori M. Takeda,
Xueying Liu,
Takahiro Nomoto,
Tekihiko Ishii,
Makoto Oba,
Yu Matsumoto,
Kazunori Kataoka.
Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting,
Biomaterials,
Vol. 113,
pp. 253-265,
Jan. 2017.
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Anraku, Yasutaka,
Kishimura, Akihiro,
Kamiya, Mako,
Tanaka, Sayaka,
Takahiro Nomoto,
Toh, Kazuko,
Matsumoto, Yu,
Fukushima, Shigeto,
Sueyoshi, Daiki,
Kano, Mitsunobu R.,
Urano, Yasuteru,
Nishiyama, Nobuhiro,
Kataoka, Kazunori.
Systemically Injectable Enzyme-Loaded Polyion Complex Vesicles as In Vivo Nanoreactors Functioning in Tumors,
Angewandte Chemie-International Edition,
Vol. 55,
No. 2,
pp. 560-565,
Dec. 2016.
Official location
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Faizah Noor,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil–Globule Transition Behavior,
Bioconjugate Chemistry,
Aug. 2016.
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Takahiro Nomoto,
Shigeto Fukushima,
Michiaki Kumagai,
Kozo Miyazaki,
Aki Inoue,
Peng Mi,
Yoshinori Maeda,
Kazuko Toh,
Yu Mastumoto,
Yuji Morimoto,
Akihiro Kishimura,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy.,
Biomaterials science,
Vol. 4,
No. 5,
pp. 826-838,
Mar. 2016.
Official location
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Hirokuni Uchida,
Keiji Itaka,
Takahiro Nomoto,
Takehiko Ishii,
Tomoya Suma,
Masaru Ikegami,
Kanjiro Miyata,
Makoto Oba,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Modulated Protonation of Side Chain Aminoethylene Repeats in N-Substituted Polyaspartamides Promotes mRNA Transfection,
Journal of the American Chemical Society,
Vol. 136,
pp. 12396-12405,
2014.
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Peng Mi,
Daisuke Kokuryo,
Horacio Cabral,
Michiaki Kumagai,
Takahiro Nomoto,
Ichio Aoki,
Yasuko Terada,
Akihiro Kishimura,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Hydrothermally synthesized PEGylated calcium phosphate nanoparticles incorporating Gd-DTPA for contrast enhanced MRI diagnosis of solid tumors,
Journal of Controlled Release,
Vol. 174,
pp. 63-71,
2014.
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Yoshinori Maeda,
Frederico Pittella,
Takahiro Nomoto,
Hiroyasu Takemoto,
Nobuhiro Nishiyama,
Kanjiro Miyata,
Kazunori Kataoka.
Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles,
Macromolecular Rapid Communications,
Vol. 35,
No. 13,
pp. 1211-1215,
2014.
Official location
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Hyun Jin Kim,
Kanjiro Miyata,
Takahiro Nomoto,
Meng Zheng,
Ahram Kim,
Xueying Liu,
Horacio Cabral,
R. James Christie,
Nobuhiro Nishiyama,
Kazunori Kataoka.
siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core,
Biomaterials,
Vol. 35,
pp. 4548-4556,
2014.
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Huabing Chen,
Ling Xiao,
Yasutaka Anraku,
Peng Mi,
Xueying Liu,
Horacio Cabral,
Aki Inoue,
Takahiro Nomoto,
Akihiro Kishimura,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer,
Journal of the American Chemical Society,
Vol. 136,
pp. 157-163,
2014.
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Satoshi Uchida,
Keiji Itaka,
Takahiro Nomoto,
Taisuke Endo,
Yu Matsumoto,
Takehiko Ishii,
Kazunori Kataoka.
An injectable spheroid system with genetic modification for cell transplantation therapy,
Biomaterials,
Vol. 35,
pp. 2499-2506,
2014.
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Christopher V. Synatschke,
Takahiro Nomoto,
Horacio Cabral,
Melanie Foertsch,
Kazuko Toh,
Yu Matsumoto,
Kozo Miyazaki,
Andreas Hanisch,
Felix H. Schacher,
Akihiro Kishimura,
Nobuhiro Nishiyama,
Axel H. E. Mueller,
Kazunori Kataoka.
Multicompartment Micelles with Adjustable Poly(ethylene glycol) Shell for Efficient in Vivo Photodynamic Therapy,
Acs Nano,
Vol. 8,
pp. 1161-1172,
2014.
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Zhishen Ge,
Qixian Chen,
Kensuke Osada,
Xueying Liu,
Theofilus A. Tockary,
Satoshi Uchida,
Anjaneyulu Dirisala,
Takehiko Ishii,
Takahiro Nomoto,
Kazuko Toh,
Yu Matsumoto,
Makoto Oba,
Mitsunobu R. Kano,
Keiji Itaka,
Kazunori Kataoka.
Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors,
Biomaterials,
Vol. 35,
pp. 3416-3426,
2014.
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Takahiro Nomoto,
Shigeto Fukushima,
Michiaki Kumagai,
Kaori Machitani,
Yu Matsumoto,
Makoto Oba,
Kanjiro Miyata,
Kensuke Osada,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer,
Nature Communications,
Vol. 5,
2014.
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Kenji Kusumoto,
Hidetaka Akita,
Taichi Ishitsuka,
Yu Matsumoto,
Takahiro Nomoto,
Ryo Furukawa,
Ayman El-Sayed,
Hiroto Hatakeyama,
Kazuaki Kajimoto,
Yuma Yamada,
Kazunori Kataoka,
Hideyoshi Harashima.
Lipid Envelope-Type Nanoparticle Incorporating a Multifunctional Peptide for Systemic siRNA Delivery to the Pulmonary Endothelium,
Acs Nano,
Vol. 7,
pp. 7534-7541,
2013.
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Theofilus A. Tockary,
Kensuke Osada,
Qixian Chen,
Kaori Machitani,
Anjaneyulu Dirisala,
Satoshi Uchida,
Takahiro Nomoto,
Kazuko Toh,
Yu Matsumoto,
Keiji Itaka,
Koji Nitta,
Kuniaki Nagayama,
Kazunori Kataoka.
Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers,
Macromolecules,
Vol. 46,
pp. 6585-6592,
2013.
-
Antje Vollrath,
Anja Schallon,
Christian Pietsch,
Stephanie Schubert,
Takahiro Nomoto,
Yu Matsumoto,
Kazunori Kataoka,
Ulrich S. Schubert.
A toolbox of differently sized and labeled PMMA nanoparticles for cellular uptake investigations,
Soft Matter,
Vol. 9,
pp. 99-108,
2013.
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Noha Gouda,
Kanjiro Miyata,
R. James Christie,
Tomoya Suma,
Akihiro Kishimura,
Shigeto Fukushima,
Takahiro Nomoto,
Xueying Liu,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA,
Biomaterials,
Vol. 34,
pp. 562-570,
2013.
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Takahiro Nomoto,
Yu Matsumoto,
Kazuko Toh,
R. James Christie,
Kanjiro Miyata,
Makoto Oba,
Horacio Cabral,
Mami Murakami,
Shigeto Fukushima,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Evaluation of the Dynamics of Drug Delivery Systems (DDS) Using Intravital Real-Time Confocal Laser Scanning Microscopy,
Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan,
Vol. 132,
pp. 1347-1354,
2012.
-
Hyun Jin Kim,
Makoto Oba,
Frederico Pittella,
Takahiro Nomoto,
Horacio Cabral,
Yu Matsumoto,
Kanjiro Miyata,
Nobuhiro Nishiyama,
Kazunori Kataoka.
PEG-detachable cationic polyaspartamide derivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor,
Journal of Drug Targeting,
Vol. 20,
pp. 33-42,
2012.
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R. James Christie,
Yu Matsumoto,
Kanjiro Miyata,
Takahiro Nomoto,
Shigeto Fukushima,
Kensuke Osada,
Julien Halnaut,
Frederico Pittella,
Hyun Jin Kim,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection,
Acs Nano,
Vol. 6,
pp. 5174-5189,
2012.
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Takahiro Nomoto,
Yu Matsumoto,
Kanjiro Miyata,
Makoto Oba,
Shigeto Fukushima,
Nobuhiro Nishiyama,
Tatsuya Yamasoba,
Kazunori Kataoka.
In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy,
Journal of Controlled Release,
Vol. 151,
pp. 104-109,
2011.
-
R. James Christie,
Kanjiro Miyata,
Yu Matsumoto,
Takahiro Nomoto,
Daniel Menasco,
Tzai Chung Lai,
Matthew Pennisi,
Kensuke Osada,
Shigeto Fukushima,
Nobuhiro Nishiyama,
Yuichi Yamasaki,
Kazunori Kataoka.
Effect of Polymer Structure on Micelles Formed between siRNA and Cationic Block Copolymer Comprising Thiols and Amidines,
Biomacromolecules,
Vol. 12,
pp. 3174-3185,
2011.
-
Stephanie Herlambang,
Michiaki Kumagai,
Takahiro Nomoto,
Souta Horie,
Shigeto Fukushima,
Makoto Oba,
Kozo Miyazaki,
Yuji Morimoto,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Disulfide crosslinked polyion complex micelles encapsulating dendrimer phthalocyanine directed to improved efficiency of photodynamic therapy,
Journal of Controlled Release,
Vol. 155,
pp. 449-457,
2011.
-
Yu Matsumoto,
Takahiro Nomoto,
Horacio Cabral,
Yoko Matsumoto,
Sumiyo Watanabe,
R. James Christie,
Kanjiro Miyata,
Makoto Oba,
Tadayoshi Ogura,
Yuichi Yamasaki,
Nobuhiro Nishiyama,
Tatsuya Yamasoba,
Kazunori Kataoka.
Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography,
Biomedical Optics Express,
Vol. 1,
pp. 1209-1216,
2010.
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Kanjiro Miyata,
Takahiro Nomoto,
Hiroyasu Takemoto,
Hyun Jin Kim,
Yu Matsumoto,
Makoto Oba,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Development of advanced polymer-based nanodevices for nucleic acids delivery,
Abstracts of Papers of the American Chemical Society,
Vol. 240,
2010.
Official location
International Conference (Reviewed)
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Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
Development of Thin-Film Light-Emitting Devices for Hyper Localized Photodynamic Therapy,
18th international photodynamic association world congress,
Photodiagnosis and Photodynamic Therapy,
Volume 46,
pp. 104167,
Apr. 2024.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
Development of Thin-Film Light-Emitting Devices for Hyper Localized Photodynamic Therapy,
18th International Photodynamic Association World Congress (IPA2023),
July 2023.
-
Yuta Kurashina,
Risa Asano,
Makoto Matsui,
Takahiro Nomoto,
Kentaro Nakamura,
Nobuhiro Nishiyama,
Yoshitaka Kitamoto.
Measurement and calculation of acoustic pressure on the effect of transdermal penetration by sonophoresis,
The 42nd Symposium on Ultrasonic Electronics,
Oct. 2021.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Kaito Kanamori,
Minoru Suzuki,
Kakeru Konarita,
Makoto Matsui,
Nobuhiro Nishiyama.
Synthesis of functional polymers boosting therapeutic potential of p-boronophenylalanine and analysis of the effect of their physicochemical properties on pharmacokinetics,
19th International Congress on Neutron Capture Therapy (19th ICNCT),
Sept. 2021.
-
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Construction of sequential self-assembled protein ternary complex utilizing boronic acid conjugated-polymer and tannic acid for protein delivery,
ACS Fall 2021,
Aug. 2021.
-
Yuta Kurashina,
Risa Asano,
Makoto Matsui,
Takahiro Nomoto,
Kentaro Nakamura,
Nobuhiro Nishiyama,
Yoshitaka Kitamoto.
Effect of sonophoresis with various nanoparticles on transdermal drug delivery,
The 12th International Conference on the Science and Technology for Advanced Ceramics,
July 2021.
-
Yuta Kurashina,
Risa Asano,
Makoto Matsui,
Takahiro Nomoto,
Kentaro Nakamura,
Nobuhiro Nishiyama,
Yoshitaka Kitamoto.
Transdermal Delivery of Large Nanoparticles via Ultrasonic Irradiation in Low-Frequency Range,
2020 International Ultrasonics Symposium(IUS2020),
Proceedings of IUS 2020,
C1P-24-1150,
Sept. 2020.
-
Kana Komoto,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Iron chelation cancer therapy using functional polymers targeting tumors,
International Symposium on Biomedical Materials for Drug/Gene Delivery,
Feb. 2020.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Poly(vinyl alcohol) for enhancing therapeutic effects of p-boronophenylalanine in neutron capture therapy,
International Symposium on Biomedical Materials for Drug/Gene Delivery,
Feb. 2020.
-
Yuto Honda,
Takahiro NOMOTO,
Makoto MATSUI,
Hiroyasu TAKEMOTO,
Yuka KAIHARA,
Yutaka MIURA,
Nobuhiro NISHIYAMA.
Development of intracellular pH- responsive protein delivery system utilizing boronic acid-conjugated polymer and tannic acid,
International Symposium on Biomedical Materials for Drug/Gene Delivery,
Feb. 2020.
-
Wanaporn Yimchuen,
Tetsuya Kadonosono,
Shinichi Sato,
Takahiro Nomoto,
Kyra See,
Hiroyuki Nakamura,
Nobuhiro Nishiyama,
Shinae Kizaka-Kondoh.
Development of photoimmunotherapy probe using a small antibody mimetic with structurally constrained anti-HER2 CDR peptides,
11th International Peptide Symposium,
June 2019.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Metabolism-controlled boron delivery systems composed of biocompatible polymers and boronophenylalanine for neutron capture therapy,
Abstracts of Papers of the American Chemical Society,
2019.
Official location
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Metabolism-controlled boron delivery systems composed of p-boronophenylalanine and poly(vinyl alcohol),
18th International Congress on Neutron Capture Therapy,
Oct. 2018.
-
Ying Yao,
Takahiro Nomoto,
Yukiya Inoue,
Minoru Suzuki,
Makoto Matsui,
Hiroyasu Takemoto,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Enhanced tumor-targeted delivery of p-boronophenylalanine using fructose-functionalized polymers for boron neutron capture therapy,
18th International Congress on Neutron Capture Therapy,
Oct. 2018.
-
Takahiro Nomoto,
Xuebo Dou,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Multiple cyclic RGD-conjugated functional polymers controlling intratumoral distribution of IRDye 700DX,
Photodynamic Therapy and Photodiagnosis Update 2018,
Sept. 2018.
-
Sjaikhurrizal El Muttaqien,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor,
256th ACS National Meeting & Exposition,
Aug. 2018.
-
Hiroyasu Takemoto,
Abduhl Hackam Ranneh,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials,
256th ACS National Meeting & Exposition,
Aug. 2018.
-
Hiroyasu Takemoto,
Huang Chih-Hao,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
2-Nitrobenzenesulfonamide Group that Responds to Intracellular Redox Potential with Enhanced Photostability for a Construction of Polymer-siRNA Conjugate System,
The 34th International Conference of Photopolymer Science and Technology (ICPST-34),
June 2017.
-
Hiroyasu Takemoto,
Huang Chih-Hao,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate.,
253rd American Chemical Society National Meeting & Exposition,
Apr. 2017.
-
Yuto Honda,
Naoki Yamada,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism.,
253rd American Chemical Society National Meeting & Exposition,
Apr. 2017.
-
Takanori Inaba,
Hiroyasu Takemoto,
Makoto Matsui,
Takahiro Nomoto,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Enhanced antitumor activity and reduced gastrointestinal toxicity of gemcitabine based on conjugation with biocompatible polymer via acetal linker,
International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS),
Mar. 2017.
-
Tsukasa Nishimori,
Naoki Yamada,
Hiroyasu Takemoto,
Kentaro Suina,
Juntaro Yamasaki,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Osamu Nagano,
Hideyuki Saya,
Nobuhiro Nishiyama.
Development of intravenously injectable sulfasalazine derivatives to treat stem-like cancer cells,
International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS),
Mar. 2017.
-
Chi-Hao Huang,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
2-nitrobenzenesulfonamide group as a new chemical linker with redox sensitivity for siRNA-conjugated polymer system,
11th Annual Symposium on Nanobiotechnology 2017,
Feb. 2017.
-
Faizah Noor,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
Artificial control of siRNA bioactivity based on the phase transition behavior of the conjugated polymeric molecule,
The 11th SPSJ International Polymer Conference (IPC2016),
Dec. 2016.
-
Chihhao Huang,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
2-nitrobenzensulfonamide groups as a chemical linker with enhanced extracellular stability and redox-sensitive cleavability for siRNA-conjugated polymer system,
The 11th SPSJ International Polymer Conference (IPC2016),
Dec. 2016.
-
Naoki Yamada,
Yuto Honda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Novel glutamine-based polymeric ligand for transporter-mediated tumor targeting,
3rd International Conference on Biomaterials Science in Tokyo,
Nov. 2016.
-
Takahiro Nomoto,
Shigeto Fukushima,
Michiaki Kumagai,
Kaori Machitani,
Kanjiro Miyata,
Makoto Oba,
Yu Matsumoto,
Kensuke Osada,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Three-layered polyplex micelle for light-induced gene transfer,
The 13th US-Japan DDS symposium,
Dec. 2015.
-
R. James Christie,
Yu Matsumoto,
Kanjiro Miyata,
Takahiro Nomoto,
Shigeto Fukushima,
Hyun Jin Kim,
Frederico Pitella,
Nobuhiro Nishiyama,
Kazunori Kataoka.
Targeted polymeric micelles for small interfering ribonucleic acid delivery,
Abstracts of Papers of the American Chemical Society,
Vol. 243,
2012.
-
Christopher V. Synatschke,
Takahiro Nomoto,
Akihiro Kishimura,
Axel H. E. Mueller,
Kazunori Kataoka.
Towards multifunctional drug delivery systems from ionic triblock terpolymer micelles,
Abstracts of Papers of the American Chemical Society,
Vol. 244,
2012.
Domestic Conference (Reviewed)
-
Yuto Honda,
Syuhei Nagao,
Hiroaki Kinoh,
Takahiro Nomoto,
Liu Xueying,
Dirisala Anjaneyulu,
Makoto Matsui,
Yutaka Miura,
Kazunori Kataoka,
Nobuhiro Nishiyama.
アデノ随伴ウイルス(AAV)の中和抗体回避および活性を向上させるAAV内包三元系複合体,
日本薬学会第142回年会,
Mar. 2022.
-
Takumi Matsuo,
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子で構築されたCas9 RNPデリバリーシステムの開発,
日本薬学会第142回年会,
Mar. 2022.
-
Yuto Honda,
Naoki Yamada,
Takahiro Nomoto,
Makoto Matsui,
Nobuhiro Nishiyama.
グルタミントランスポーターを高密度で発現しているがん細胞を認識する機能性高分子の開発,
第43回日本バイオマテリアル学会大会,
Nov. 2021.
-
Syuhei Nagao,
Yuto Honda,
Hiroaki Kinoh,
Takahiro Nomoto,
Liu Xueying,
Dirisala Anjaneyulu,
Makoto Matsui,
Yutaka Miura,
Kazunori Kataoka,
Nobuhiro Nishiyama.
アデノ随伴ウイルス(AAV)中和抗体回避を可能にする全身投与型AAV搭載三元系複合体の開発,
第43回日本バイオマテリアル学会大会,
Nov. 2021.
-
Takumi Matsuo,
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子の自己会合によって構成されたCas9 RNPデリバリーシステムの開発,
第11回CSJ化学フェスタ2021,
Oct. 2021.
-
Koichi Usukura,
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
官能基が異なるボロン酸導入高分子とタンニン酸で構成されたタンパク質三元系複合体の安定性評価,
第70回高分子討論会,
Sept. 2021.
-
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
効率的なタンパク質送達を指向したタンニン酸とフェニルボロン酸導入高分子で構成されたタンパク質内包三元系複合体の構築,
第70回高分子討論会,
Sept. 2021.
-
Takumi Matsuo,
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子で構築された自己会合型Cas9 RNP送達システムの開発,
第70回高分子討論会,
Sept. 2021.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Kaito Kanamori,
Minoru Suzuki,
Kakeru Konarita,
Makoto Matsui,
Nobuhiro Nishiyama.
側鎖に糖構造を有する高分子とボロノフェニルアラニンから構成される薬物送達システムの設計,
第17回日本中性子捕捉療法学会学術大会,
July 2021.
-
Yuto Honda,
Natsumi Fukuhara,
Nao Ukita,
Makoto Matsui,
Satoshi Ohno,
Takahiro Nomoto,
Nobuhiro Nishiyama,
Katsuyuki Hoshina,
Yutaka Miura.
ボロン酸エステルを介したスタチン内包高分子型ミセルの構築および薬理効果,
第37回日本DDS学会学術集会,
June 2021.
-
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子から成る自己会合型ナノリアクターの構築および酵素プロドラッグ療法への応用,
第37回日本DDS学会学術集会,
June 2021.
-
Syuhei Nagao,
Yuto Honda,
Hiroaki Kinoh,
Takahiro Nomoto,
Liu Xueying,
Dirisala Anjaneyulu,
Makoto Matsui,
Yutaka Miura,
Kazunori Kataoka,
Nobuhiro Nishiyama.
アデノ随伴ウイルス(AAV)ベクターの中和抗体および副作用を克服するAAV/タンニン酸/ボロン酸導入高分子三元系複合体の構築,
第37回日本DDS学会学術集会,
June 2021.
-
Ohashi Ryotaro,
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子で構成されるオボアルブミン封入三元系複合体の構築とがん免疫療法への応用,
第37回日本DDS学会学術集会,
June 2021.
-
Takumi Matsuo,
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸修飾高分子からなるCRISPR/Casタンパク質デリバリーシステムの開発,
第37回日本DDS学会学術集会,
June 2021.
-
Yuto Honda,
Takahiro Nomoto,
Makoto Matsui,
Yutaka MiuraNobuhiro Nishiyama,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子の自己会合によって形成されたナノリアクターの酵素プロドラッグ療法への応用,
第31回バイオ・高分子シンポジウム,
June 2021.
-
Takahiro Nomoto,
Xuebo Dou,
Hiroyasu Takemoto,
Nobuhiro Nishiyama.
多価環状RGDペプチド担持高分子型光増感剤によるphotochemical internalizationの検討,
LASER WEEK IN KOCHI,
Oct. 2020.
-
Takahiro Nomoto.
ポリビニルアルコールを利用したホウ素中性子捕捉療法の治療効果向上,
日本放射線影響学会第63回大会,
Oct. 2020.
-
Yudi Sun,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
ASO-分岐PEG結合体を内包する小分子キャリアの開発および機能評価,
Sept. 2020.
-
Kana Komoto,
Takahiro Nomoto,
S Muttaqien,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
がん鉄キレート療法のための効率的な除鉄を実現する機能性高分子の開発,
第69回高分子討論会,
Sept. 2020.
-
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
高分子修飾によるsiRNA周囲の空間支配と薬理機構制御,
Sept. 2020.
-
Masahiro Toyoda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
腫瘍内pH応答性の獲得を目指した高分子ベタイン内の両イオン性基の種類・間隔の検討,
Sept. 2020.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Kaito Kanamori,
Kakeru Konarita,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
Development of functional polymers to boost therapeutic potential of boronophenylalanine in neutron capture therapy,
第69回高分子討論会,
Sept. 2020.
-
ムツタキンシャイクリザルエル,
Yutaka Miura,
Haochen Guo,
Takahiro Nomoto,
Kana Komoto,
S Muttaqien,
Xiaohang Sun,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Polymeric iron-chelators for improving high- dose vitamin C therapy,
第69回高分子討論会,
Sept. 2020.
-
I Dewa Agung Panji Dwipayana,
Yuto Honda,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Development of a versatile drug delivery system using tannic acid and boronic acid-conjugated polymer,
第69回高分子討論会,
Sept. 2020.
-
Hiroyasu Takemoto,
Takanori Inaba,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
"環状アセタール構造に基づくゲムシタビン担持型高分子の開発とその機能評価 および副作用低減",
第36回日本DDS学会学術集会,
Aug. 2020.
-
Haochen Guo,
Takahiro Nomoto,
Kana Komoto,
S Muttaqien,
Xiaohang Sun,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Effect of polymeric iron-chelators on high-dose vitamin C therapy,
第36回日本DDS学会学術集会,
Aug. 2020.
-
Masahiro Toyoda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
高分子ベタイン内のイオン性基の種類・間隔の制御と腫瘍内pH応答性への展開,
第69回高分子学会年次大会,
May 2020.
-
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
"環状アセタール構造を介したゲムシタビンのポリアミノ酸への導入と薬効増大 および副作用低減",
May 2020.
-
Takahiro Nomoto.
代謝制御型ドラッグデリバリーシステムによるホウ素中性子捕捉療法,
日本薬学会第140年会,
Mar. 2020.
-
1. 野本貴大,
Shigeto Fukushima,
Michiaki Kumagai,
Kozo Miyazaki,
Aki Inoue,
Peng Mi,
Yoshinori Maeda,
籐加珠子,
Yu Mastumoto,
Yuji Morimoto,
Akihiro Kishimura,
Nobuhiro Nishiyama,
Kazunori Kataoka,
Takahiro Nomoto.
効率的な光線力学療法を指向したハイブリッド型光増感剤送達システム,
日本薬学会 第138年会,
Mar. 2018.
-
Hiroyasu Takemoto,
Takanori Inaba,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上,
Photopolymer Science and Technology (ICPST-34),
July 2017.
-
Naoki Yamada,
Yuto Honda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters,
第66回高分子年次大会,
May 2017.
-
Hiroyasu Takemoto,
Chih Hao Huang,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
2-nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system,
第66回高分子年次大会,
May 2017.
-
Shunya Sakuma,
Ranneh Hackam,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-,
第66回高分子年次大会,
May 2017.
-
Gyomon Ryu,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発,
第66回高分子年次大会,
May 2017.
-
Hiroki Shinkai,
Naoki Yamada,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発,
第66回高分子年次大会,
May 2017.
-
Ranneh Hackam,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Development of stealth shell based on polycarboxybetaine structure tuned to selectively interact with cells in tumor extracellular acidic pH,
日本薬学会第137年会,
Mar. 2017.
-
Junhyun Kim,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
高分子ミセルにおける内核構造の安定性の差異がもたらす腫瘍集積性に関する考察,
第65回高分子討論会,
Sept. 2016.
-
Xiaohang Sun,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
がんへの薬剤の集積状態をレポートするナノメディシンの開 発,
第65回高分子討論会,
Sept. 2016.
-
Chih Ling Wang,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
A Novel Design of Polyion Complex (PIC) with The Pyruvate-Reactive Function toward Enhanced Cytosolic Release of siRNA,
第65回高分子討論会,
Sept. 2016.
-
Faizah Noor,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
Development of siRNA-conjugated polymer with coil-globule transition behavior for an artificially controlled gene silencing activity,
第65回高分子討論会,
Sept. 2016.
-
NOOR,
Hiroyasu Takemoto,
Takahiro Nomoto,
Nobuhiro Nishiyama.
Development of thermoresponsive polymer-siRNA conjugates for controlled RNAi activity,
第65回高分子学会年次大会,
May 2016.
International Conference (Not reviewed / Unknown)
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
Development of wireless light-emitting devices based on polymeric thin films and evaluation of their hyperlocalized photosensitization,
the 12th World Biomaterials Congress,
May 2024.
-
Takahiro Nomoto.
Development of drug delivery systems for boron neutron capture therapy using functional polymers,
Tsukuba Conference 2021,
Sept. 2021.
-
Takahiro Nomoto.
Drug delivery systems targeting tumour microenvironment for near-infrared photodynamic therapy,
19th Congress of the European Society for Photobiology,
Aug. 2021.
-
Takahiro Nomoto.
Photodynamic therapy using functional polymers targeting tumor microenvironment,
The 3rd Workshop for Japan-Korea Young Scientists on Pharmaceutics,
July 2020.
-
Takahiro Nomoto,
Sjaikhurrizal El Muttaqien,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
Photodynamic therapy utilizing functional polymers that exert pH-responsive isothermal phase transition,
ICPST-36,
June 2020.
-
Takahiro Nomoto,
Xuebo Dou,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Photosensitizer delivery to tumor cells and tumor-associated vasculature using functional polymers,
7th International ALA and Prophyrin Symposium (IAPS7),
Dec. 2019.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Kaito Kanamori,
Makoto Matsui,
Hiroyasu Takemoto,
Nobuhiro Nishiyama.
Boosting Therapeutic Potential of p-Boronophenylalanine Using Biocompatible Polymers,
The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT),
Sept. 2019.
-
Kaito Kanamori,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
BPA delivery system utilizing sugar-modified polymers forming stable boronate esters,
The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT),
The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT),
Sept. 2019.
-
Nobuhiro Nishiyama,
Kana Komoto,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui.
Development of polymeric iron chelator for cancer therapy,
The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics,
July 2019.
-
Kaito Kanamori,
Takahiro Nomoto,
Minoru Suzuki,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
Boron Delivery Using Sugar-Modified Polymers for Neutron Capture Therapy,
The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics,
2019.
-
Sayaka Onodera,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
Conjugation of siRNA and a polymer with coil-globule transition property for control of siRNA activity around body temperature,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Yuka Kaihara,
Makoto Matsui,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Development of novel drug delivery system for enhancing bone regeneration in bone fracture model mouse,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Yuto Honda,
Naoki Yamada,
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism.,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Hiroyasu Takemoto,
Abdul-Hackam Ranneh,
Takahiro Nomoto,
Makoto Matsui,
Nobuhiro Nishiyama.
Ethylenediamine-based polyzwitterion that becomes cationic at tumorous pH for effective tumor accumulation of the coated nanomaterials,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Sjaikhurrizal El Muttaqien,
松井 誠,
武元 宏泰,
野本 貴 大,
友田 敬士郎,
西山 伸宏.
Poly(N-isopropylacrylamide) derivatives exering remarkable LCST shift in response to slight pH chnge via detachment of hydrophilic acid-labile moiety,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Sun Xiaohang,
Taknaori Inaba,
Kazuki Ohsakama,
Mika Shishido,
Hiroki Yoshioka,
武元宏泰,
野本貴大,
松井誠,
友田敬士郎,
西山伸宏.
Development of degradable poly(ethylene glycol)(PEG) derivatives for suppressing cellular vacuolations,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Gyomon Ryu,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Development of poly(amino acid)-based carrier that loads gemcitabine via reversible linkage and its evaluation using pancreatic cancer model,
The 12th SPSJ International Polymer Conference (IPC2018),
Dec. 2018.
-
Naoki Yamada,
Yuto Honda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Glutamine-Functionalized Polymer for Tumor-Selective High Affinity by Sensing Dense Glutamine Transporters Associated with Aberrant Metabolism,
14th US-JAPAN Symposium on Drug Delivery Systems,
Dec. 2017.
-
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
2-nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate,
14th US-JAPAN Symposium on Drug Delivery Systems,
Dec. 2017.
Domestic Conference (Not reviewed / Unknown)
-
Masato Saito,
Daiki Tokura,
Yasufumi Yokoshiki,
Takashi Tokuda,
Takahiro Nomoto,
Toshinori Fujie.
光線力学療法に向けた薄膜状発光デバイスの開発と抗腫瘍能評価,
第85回応用物理学会秋季学術講演会,
Sept. 2024.
-
Anudari Batbayar,
Ryotaro Ohashi,
Yuto Honda,
Takahiro Nomoto,
Yutaka Miura,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用,
第45回日本バイオマテリアル学会大会,
Nov. 2023.
-
Yuto Honda,
Shuhei Nagao,
Hiroaki Kinoh,
Nozomi Matsudaira,
Xueying Liu,
Takahiro Nomoto,
Anjaneyulu Dirisala,
Yutaka Miura,
Kazunori Kataoka,
Nobuhiro Nishiyama.
集束超音波と高分子複合体を組み合わせた脳選択的AAV送達システムの構築,
第44回日本バイオマテリアル学会大会,
Nov. 2023.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
異なる発色光の LED 搭載デバイスによる局所的な光増感作用の制御,
第45回日本バイオマテリアル学会大会,
Nov. 2023.
-
Daiki Tokura,
Kakeru Konarita,
Minoru Suzuki,
Yuto Honda,
Nobuhiro Nishiyama,
Takahiro Nomoto.
PHPMA を基盤としたホウ素中性子捕捉療法用薬物送達システムの開発,
第72回高分子討論会,
Sept. 2023.
-
Nozomi Matsudaira,
Yuto Honda,
Shuhei Nagao,
喜納宏明,
Takahiro Nomoto,
Yutaka Miura,
Nobuhiro Nishiyama.
アデノ随伴ウイルス (AAV)の腫瘍選択性を向上させる環状ペプチドリガンド導入三元系 複合体の開発,
第29回日本遺伝子細胞治療学会学術集会,
Sept. 2023.
-
Yuto Honda,
Takumi Matsuo,
Takahiro Nomoto,
Nobuhiro Nishiyama.
超分子複合体を基盤とした全身投与可能なCas9-sgRNP RNP送達システムの開発,
第29回日本遺伝子細胞治療学会学術集会,
Sept. 2023.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
局所的な光増感作用発現のための無線給電型薄膜状発光デバイスの開発,
72nd Symposium on Macromolecules,
Sept. 2023.
-
Nozomi Matsudaira,
Yuto Honda,
Shuhei Nagao,
喜納宏明,
Takahiro Nomoto,
Yutaka Miura,
Nobuhiro Nishiyama.
腫瘍標的機能を備えた環状ペプチド搭載アデノ随伴ウイルス(AAV)三元系複合体の開発,
第39回日本DDS学会学術集会,
July 2023.
-
Yuto Honda,
シャイクリザル エル ムツタキン,
Nobuhiro Nishiyama,
Takahiro Nomoto.
ボロン酸エステルを基盤とした細胞内相転移による高分子-細胞間相互作用制御および 薬物送達キャリアとしての応用,
第39回日本DDS学会学術集会,
July 2023.
-
Anudari Batbayar,
Ryotaro Ohashi,
Yuto Honda,
Takahiro Nomoto,
Yutaka Miura,
Nobuhiro Nishiyama.
タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用,
第39回日本DDS学会学術集会,
July 2023.
-
Motoaki Kobayashi,
Aria Ghasemizadeh,
Masahiro Toyoda,
Wanphiwat Chintrakulchai,
Yijung Sung,
Xin Shen,
Yuto Honda,
Takahiro Nomoto,
Yutaka Miura,
Nobuhiro Nishiyama.
ポリベタイン修飾脂質ナノ粒子を用いたpH変化をトリガーとする腫瘍選択的siRNA送達システムの開発,
第39回日本DDS学会学術集会,
July 2023.
-
Yuto Honda,
Takumi Matsuo,
Takahiro Nomoto,
Yuriko Osakabe,
Nobuhiro Nishiyama.
高分子三元系複合体を基盤とした全身投与型 Cas9-sgRNP RNP 送達システムの開発,
日本ゲノム編集学会 第8回大会,
June 2023.
-
Yuto Honda,
Kouichi Usukura,
Takahiro Nomoto,
Nobuhiro Nishiyama.
ポリフェノールと自己会合型三元系複合体を形成するボロン 酸導入高分子の構造検討と機械学習を用いた解析,
第72回高分子学会年次大会,
May 2023.
-
Nozomi Matsudaira,
Yuto Honda,
Shuhei Nagao,
Hiroaki Kinoh,
Takahiro Nomoto,
Xueying Liu,
Anjaneyulu Dirisala,
Yutaka Miura,
Kazunori Kataoka,
Nobuhiro Nishiyama.
腫瘍細胞標的機能を備えた全身投与型アデノ随伴ウイルス(AAV)三元系複合体の開発,
Nov. 2022.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
メトロノミック光線力学療法に向けたフレキシブル薄膜状発光デバイスの開発,
第44回日本バイオマテリアル学会大会,
Nov. 2022.
-
Anudari Batbayar,
Haochen Guo,
Takahiro Nomoto,
Yan Ming Voon,
Nobuhiro Nishiyama.
Developing of Ovalbumin-Loaded Ternary Complexes Utilizing Tannic Acid and Phenylboronic Acid Conjugated Polymers for Cancer Immunotherapy,
第44回日本バイオマテリアル学会大会,
Nov. 2022.
-
Haochen Guo,
Takahiro Nomoto,
Hiroaki Kinoh,
Jun Ishihara,
Nobuhiro Nishiyama.
Polymeric Iron Chelator Modulating Tumor Immune Microenvironment,
第81回癌学会学術総会,
Oct. 2022.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takaya Tokuda,
Toshinori Fujie.
無線給電式薄膜状発光デバイスの開発と局所的光増感作用の検証,
第83回応用物理学会秋季学術講演会,
Sept. 2022.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
Hyper Localized Photodynamic Therapy using Thin-Film Light-Emitting Devices,
FSE若手4th event,
July 2022.
-
Takahiro Nomoto.
精密設計高分子を基盤とした薬物送達システムによるPDT,
第31回日本光線力学学会学術講演会,
Oct. 2021.
-
Masato Saito,
Takahiro Nomoto,
Yasufumi Yokoshiki,
Takashi Tokuda,
Toshinori Fujie.
印刷配線を用いた無線給電式薄膜状発光デバイスの開発,
第82回応用物理学会春季学術講演会,
Sept. 2021.
-
Haochen Guo,
Takahiro Nomoto,
Makoto Matsui,
Yan Ming Voon,
Yijung Sung,
Yutaka Miura,
Nobuhiro Nishiyama.
高分子鉄キレート剤を利用した腫瘍免疫逃避環境の克服,
第70回高分子討論会,
Sept. 2021.
-
Takahiro Nomoto,
Kakeru Konarita,
Minoru Suzuki,
Makoto Matsui,
Nobuhiro Nishiyama.
ポリビニルアルコールを利用したボロノフェニルアラニンの中性子捕捉療法における治療効果向上,
第37回日本DDS学会学術集会,
June 2021.
-
Haochen Guo,
Takahiro Nomoto,
Makoto Matsui,
Kana Komoto,
S Muttaqien,
Yutaka Miura,
Nobuhiro Nishiyama.
高分子鉄キレート剤を用いた腫瘍内鉄イオン制御とそのアスコルビン酸の抗腫瘍効果への影響に関する検討,
第37回日本DDS学会学術集会,
June 2021.
-
Kakeru Konarita,
Takahiro Nomoto,
Kaito Kanamori,
Minoru Suzuki,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Poly(vinyl alcohol)と D-4-boronophenylalanine から構成される 薬物送達システムによるホウ素中性子捕捉療法の検討,
第70回高分子学会年次大会,
May 2021.
-
Takahiro Nomoto.
超低侵襲ケミカルサージェリーを目指した高分子コンジュゲート型DDSの設計,
日本薬学会第141年会,
Mar. 2021.
-
Takahiro Nomoto.
Drug delivery using functional polymer-conjugates,
Topical Meeting on Condensed-Matter Chemistry on Actinides,
Feb. 2021.
-
Takahiro Nomoto,
Yuto Honda,
Yuka Kaihara,
Hiroaki Kinoh,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
タンニン酸とボロン酸ケミストリーを利用した高分子複合体の簡便調製法,
第 3 回 COI 学術交流会,
July 2020.
-
Guo Haochen,
Takahiro Nomoto,
Kana Komoto,
Sun Xiaohang,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
Development of polymeric iron-chelators for enhancing high-dose vitamin C therapy,
第 3 回 COI 学術交流会,
July 2020.
-
Takahiro Nomoto,
Makoto Matsui,
Hiroyasu Takemoto,
Yuka Kaihara,
Yutaka Miura,
Nobuhiro Nishiyama.
ボロン酸導入高分子とタンニン酸を用いた細胞内環境応答タンパク質送達システムの構築,
第41回日本バイオマテリアル学会大会,
Nov. 2019.
-
Kana Komoto,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
がん治療のための効率的な生体内の除鉄を実現する機能性高分子の開発,
第41回日本バイオマテリアル学会大会,
Nov. 2019.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Kaito Kanamori,
Minoru Suzuki,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
生体適合性高分子とボロノフェニルアラニンから構成される中性子捕捉療法用代謝制御型ホウ素送達システム,
第41回日本バイオマテリアル学会大会,
Nov. 2019.
-
Hiroyasu Takemoto,
Takanori Inaba,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
環状アセタール構造に基づくゲムシタビンの高分子修飾と制がん効果増大及び副作用低減,
第41回日本バイオマテリアル学会大会,
Nov. 2019.
-
Hiroyasu Takemoto,
Muhammad Aziz,
Ranneh Hackam,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
腫瘍内pH応答性高分子ベタインの設計と被覆ナノ粒子への展開,
第68回高分子討論会,
Sept. 2019.
-
Takahiro Nomoto,
S Muttaqien,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
腫瘍内低pH環境に応答して親水-疎水相転移挙動を示す高分子コンジュゲート型光増感剤,
PhotoDynamic Medicine 2019,
Sept. 2019.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Kaito Kanamori,
Minoru Suzuki,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
生体適合性高分子とp-boronophenylalanineから構成されるホウ素送達システムの開発と構成高分子の物性が体内動態と治療効果に与える影響に関する考察,
第16回日本中性子捕捉療法学会,
Sept. 2019.
-
Yuto Honda,
Naoki Yamada,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
がん細胞の高密度グルタミントランスポーターと選 択的な相互作用を示す機能性高分子の開発,
第68回高分子討論会,
Sept. 2019.
-
Sayaka Onodera,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Yutaka Miura,
Nobuhiro Nishiyama.
温度応答性高分子-siRNA結合体の合成と外部刺激によるsiRNAの生物活性制御,
第68回高分子討論会,
Sept. 2019.
-
Kana Komoto,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
がん治療を指向した生体内鉄イオンをキレートする機能性高分子の開発,
第35回日本DDS学会学術集会,
July 2019.
-
Hiroyasu Takemoto,
Muhammad Aziz,
Takahiro Nomoto,
Makoto Matsui,
Nobuhiro Nishiyama.
腫瘍 pH 応答性高分子ベタインの開発とナノ粒子のがん送達への展開,
第35回日本DDS学会学術集会,
July 2019.
-
Sayaka Onodera,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
温度応答性高分子-siRNA結合体とのポリイオンコンプレックス形成と外部刺激によるsiRNA の薬効制御,
July 2019.
-
Makoto Matsui,
Yuka Kaihara,
Hiroyasu Takemoto,
Takahiro Nomoto,
Nobuhiro Nishiyama.
薬物送達技術を応用した新規骨折治療法の開発,
第35回日本DDS学会学術集会,
July 2019.
-
Kaito Kanamori,
Takahiro Nomoto,
Minoru Suzuki,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
ボロン酸エステルを利用したホウ素薬物送達キャリアの開発,
第35回日本DDS学会学術集会,
July 2019.
-
Masahiro Toyoda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Nobuhiro Nishiyama.
腫瘍内pH応答性高分子ベタイン内のイオン性基間距離の検討,
第68回高分子学会年次大会,
May 2019.
-
Kaito Kanamori,
Takahiro Nomoto,
Minoru Suzuki,
Hiroyasu Takemoto,
Makoto Matsui,
Nobuhiro Nishiyama.
糖修飾高分子とホウ素薬物から構成される薬物送達システムの開発,
第68回高分子学会年次大会,
May 2019.
-
Yuto Honda,
Naoki Yamada,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
がん細胞の高密度グルタミントランスポーターを標的として選択的な相互作用を示す機能性高分子の開発,
第68回高分子学会年次大会,
May 2019.
-
Sayaka Onodera,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
ポリイオンコンプレックスを利用した温度応答性高分子-siRNA結合体の細胞内導入と外部刺激によるsiRNAの生物活性制御,
第68回高分子学会年次大会,
May 2019.
-
Takahiro Nomoto.
代謝制御型ホウ素送達システムを用いた中性子捕捉療法,
第2回ナノマシン研究会,
Dec. 2018.
-
Takahiro Nomoto.
精密設計高分子を基盤とした光増感剤送達システムの開発,
第3期第2回「レーザーバイオ医療」技術専門委員会,
Nov. 2018.
-
Yuto Honda,
Naoki Yamada,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
グルタミン代謝が亢進したがん細胞の高密度グルタ ミントランスポーターを認識してアフィニティを示す機能性高 分子,
第67回高分子討論会,
Sept. 2018.
-
Gyomon Ryu,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Development of gemcitabine-conjugated poly(amino acid) and its evaluation using pancreatic tumor model,
第67回高分子討論会,
Sept. 2018.
-
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Minoru Suzuki,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
生体適合性機能性高分子によるボロノフェニルアラニンの代謝制御と治療効果の向上,
第15回日本中性子捕捉療法学会学術大会,
Sept. 2018.
-
Takahiro Nomoto.
物理エネルギー誘導型ケミカルサージェリーを実現するドラッグデリバリーシステム,
第5回創薬塾,
Aug. 2018.
-
Ying Yao,
Takahiro Nomoto,
Yukiya Inoue,
Minoru Suzuki,
Makoto Matsui,
Hiroyasu Takemoto,
Keishiro Tomoda,
Nobuhiro Nishiyama.
Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy,
第34回日本DDS学会学術集会,
June 2018.
-
Takahiro Nomoto,
Xuebo Dou,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討,
第34回日本DDS学会学術集会,
June 2018.
-
Hiroyasu Takemoto,
Ranneh Abdul-Hackam,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Yuki Mochida,
Mitsuru Naito,
Nobuhiro Nishiyama.
腫瘍内環境を認識する高分子ベタインの開発とナノ粒子の効率的な腫瘍集積への展開,
第67回高分子年次大会,
May 2018.
-
Sayaka Onodera,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Nobuhiro Nishiyama.
siRNAへのCoil-globule挙動を有する高分子の結合と生体温度付近での遺伝子発現抑制能の精密制御,
第67回高分子年次大会,
May 2018.
-
Gyomon Ryu,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
可逆的にゲムシタビンを担持するポリアミノ酸型キャリアの開発とすい臓がんモデルでの機能評価,
第67回高分子年次大会,
May 2018.
-
Naoki Yamada,
Yuto Honda,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
がん選択的に相互作用するグルタミン担持高分子の創製と機能評価,
第39回日本バイオマテリアル学会大会,
Nov. 2017.
-
Hiroki Shinkai,
Naoki Yamada,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発,
第66回高分子討論会,
Sept. 2017.
-
Hiroyasu Takemoto,
Takanori Inaba,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減,
第66回高分子討論会,
Sept. 2017.
-
Xuebo Dou,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
光増感剤結合型高分子における多岐環状RGDペプチドの腫瘍集積性と腫瘍内分布への効果の検討,
第66回高分子討論会,
Sept. 2017.
-
Shunya Sakuma,
Abdul-Hackam RANNEH,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Nobuhiro Nishiyama.
腫瘍指向性ステルス高分子の開発とDDSへの応 用-ベタイン構造内アニオン性基の影響-,
第66回高分子討論会,
Sept. 2017.
Other Publication
-
Takahiro Nomoto.
ポリビニルアルコールでホウ素中性子捕捉療法の治療効果を向上,
週刊医学のあゆみ,
Vol. 277,
No. 2,
Apr. 2021.
-
Takahiro Nomoto.
ポリビニルアルコールに秘められた可能性:ホウ素送達システムへの応用,
バイオマテリアル-生体材料-,
Vol. 39,
No. 2,
Apr. 2021.
-
Takahiro Nomoto,
Nobuhiro Nishiyama.
ポリビニルアルコールによるBNCT治療効果向上について,
Isotope News,
No. 772,
Dec. 2020.
-
Takahiro Nomoto.
安価な「ポリビニルアルコール」を利用した新たながん治療の可能性,
月刊マテリアルステージ,
Vol. 20,
No. 5,
Aug. 2020.
-
Takahiro Nomoto.
ポリビニルアルコール:ボロノフェニルアラニンの治療効果を高める添加剤,
NCT letter,
Aug. 2020.
-
Takahiro Nomoto.
研究物語 スライムから発想を得たがん治療,
月刊「化学」,
July 2020.
-
Takahiro Nomoto,
Nobuhiro Nishiyama.
Design of drug delivery systems for physical energy-induced chemical surgery,
Biomaterials,
Elsevier,
Volume 178,
pp. 583-596,
Sept. 2018.
Official location
Patent
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Yutaka Miura,
Takahiro Nomoto,
Makoto Matsui,
Masahiro Toyoda,
Aria Ghasemizadeh.
pH応答性脂質誘導体.
Patent.
Published.
国立大学法人東京工業大学, 日油株式会社.
2022/07/06.
PCT/JP2022/026863.
2023/01/12.
WO 2023/282296.
2023.
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Yutaka Miura,
Takahiro Nomoto,
Makoto Matsui,
Masahiro Toyoda,
Aria Ghasemizadeh.
高純度pH応答性ポリマー及びその製造方法.
Patent.
Published.
国立大学法人東京工業大学, 日油株式会社.
2022/07/06.
PCT/JP2022/026864.
2023/01/12.
WO 2023/282297.
2023.
-
Nobuhiro Nishiyama,
Takahiro Nomoto,
Haochen Guo,
Kaito Kanamori,
Naoki Yamada,
Makoto Matsui,
Hiroyasu Takemoto.
L型アミノ酸トランスポーター1を標的とした高分子.
Patent.
Published.
国立大学法人東京工業大学, 第一三共株式会社.
2022/04/28.
特願2022-075447.
2023/11/10.
特開2023-164109.
2023.
-
Nobuhiro Nishiyama,
Yuto Honda,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui.
複合体、医薬、癌治療剤、キット及び結合体.
Patent.
Published.
国立大学法人東京工業大学, 公益財団法人川崎市産業振興財団.
2020/05/29.
PCT/JP2020/021301.
2020/12/03.
WO 2020/241819.
2020.
-
Nobuhiro Nishiyama,
Takahiro Nomoto,
Kana Komoto,
Hiroyasu Takemoto,
Makoto Matsui.
結合体、及び癌治療剤.
Patent.
Published.
国立大学法人東京工業大学, SBIファーマ株式会社.
2020/04/23.
PCT/JP2020/017421.
2020/10/29.
WO 2020/218390.
2020.
-
Nobuhiro Nishiyama,
Makoto Matsui,
Hiroyasu Takemoto,
Takahiro Nomoto,
Xiaohang Sun.
分岐型分解性ポリエチレングリコール結合体.
Patent.
Registered.
国立大学法人東京工業大学, 日油株式会社.
2020/03/26.
特願2020-055412.
2020/10/08.
特開2020-164856.
特許第7411189号.
2023/12/27
2023.
-
Nobuhiro Nishiyama,
Makoto Matsui,
Hiroyasu Takemoto,
Takahiro Nomoto,
Xiaohang Sun.
分岐型分解性ポリエチレングリコール誘導体.
Patent.
Registered.
国立大学法人東京工業大学, 日油株式会社.
2020/03/26.
特願2020-055411.
2020/10/08.
特開2020-164855.
特許第7411188号.
2023/12/27
2023.
-
Nobuhiro Nishiyama,
Makoto Matsui,
Hiroyasu Takemoto,
Kazuki Miyauchi,
Takahiro Nomoto,
Keishiro Tomoda.
分解性ポリエチレングリコール結合体.
Patent.
Registered.
国立大学法人東京工業大学, 日油株式会社.
2019/03/29.
特願2019-068351.
2019/10/10.
特開2019-172673.
特許第7249591号.
2023/03/23
2023.
-
Nobuhiro Nishiyama,
Makoto Matsui,
Hiroyasu Takemoto,
Kazuki Miyauchi,
Takahiro Nomoto,
Keishiro Tomoda.
分解性ポリエチレングリコール誘導体.
Patent.
Registered.
国立大学法人東京工業大学, 日油株式会社.
2019/03/29.
特願2019-068350.
2019/10/10.
特開2019-173014.
特許第7205827号.
2023/01/06
2023.
-
Nobuhiro Nishiyama,
Takahiro Nomoto,
Yukiya Inoue,
Ying Yao,
Kaito Kanamori,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda.
p-ボロノフェニルアラニン誘導体及びそれを含む組成物、並びにそれらを製造するためのキット.
Patent.
Registered.
国立大学法人東京工業大学, ステラファーマ株式会社.
2019/02/19.
特願2020-500974.
2021/02/12.
再表2019/163790.
特許第7219925号.
2023/02/01
2023.
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Keishiro Tomoda,
Takahiro Nomoto,
Makoto Matsui.
pH応答性ポリマー及び薬物送達システム.
Patent.
Registered.
国立大学法人東京工業大学.
2017/12/05.
特願2018-556597.
2019/10/24.
再表2018/110366.
特許第6995375号.
2021/12/17
2021.
-
Nobuhiro Nishiyama,
Takahiro Nomoto,
Hiroyasu Takemoto,
Makoto Matsui,
Keishiro Tomoda.
温度応答性ポリマー及びそれを含む組成物.
Patent.
Published.
国立大学法人東京工業大学.
2017/11/01.
特願2017-211893.
2019/06/06.
特開2019-085438.
2019.
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui,
Naoki Yamada,
Yuto Honda.
グルタミントランスポーターと多価結合することができるリガンド、及び当該リガンドを含む組成物.
Patent.
Registered.
国立大学法人東京工業大学, 国立大学法人大阪大学.
2017/08/17.
特願2018-535630.
2019/06/20.
特開(再表)2018-037996.
特許第7076104号.
2022/05/19
2022.
-
Nobuhiro Nishiyama,
Hiroyuki Nakamura,
Hiroyasu Takemoto,
Takahiro Nomoto.
ホウ素クラスター結合ペプチド化合物.
Patent.
Published.
国立大学法人東京工業大学, 味の素株式会社, 公益財団法人川崎市産業振興財団, 国立大学法人東京大学.
2017/03/23.
特願2018-507416.
2019/02/28.
再表2017/164334.
2019.
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Takanori Inaba,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda.
薬物送達用担体及び薬物送達システム.
Patent.
Published.
国立大学法人東京工業大学.
2017/02/20.
特願2017-029264.
2020/04/23.
特開2020-063191.
2020.
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Takahiro Nomoto,
Makoto Matsui,
Keishiro Tomoda,
Naoki Yamada,
Tsukasa Nishimori.
抗腫瘍剤.
Patent.
Registered.
国立大学法人東京工業大学, 学校法人慶應義塾.
2017/01/05.
特願2017-560416.
2018/11/01.
再表2017/119462.
特許第6803589号.
2020/12/03
2020.
-
Nobuhiro Nishiyama,
Hiroyasu Takemoto,
Takahiro Nomoto,
Keishiro Tomoda,
Makoto Matsui.
結合体.
Patent.
Published.
国立大学法人東京工業大学.
2016/06/07.
特願2016-113664.
2017/12/14.
特開2017-218408.
2017.
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