論文

• Chie Hashimoto, Wataru Nomura, Tetsuo Narumi, Fujino, Masayuki, Hiroshi Tsutsumi, Masaki Haseyama, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura. Anti-HIV-1 Peptide Derivatives Based on the HIV-1 Co-receptor CXCR4, ChemMedChem, Vol. 8, No. 10, pp. 1668-1672, Oct. 2013.  公式リンク  
  
• Hiroshi Tsutsumi, Seiichiro Abe, Tomoaki Mino, Wataru Nomura, Hirokazu Tamamura. Intense Blue Fluorescence in a Leucine Zipper Assembly, ChemBioChem, Vol. 12, No. 5, pp. 691-694, Feb. 2011.  公式リンク  
  
• Wataru Nomura, Tomoaki Mino, Tetsuo Narumi, Nami Ohashi, Akemi Masuda, Chie Hashimoto, Hiroshi Tsutsumi, Hirokazu Tamamura. Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins, Biopolymers, Vol. 94, No. 6, pp. 843-852, Nov. 2010.  公式リンク  
  
• Shintaro Suzuki, Maddali, Kasthuraiah, Chie Hashimoto, Urano, Emiko, Nami Ohashi, Tomohiro Tanaka, Ozaki, Taro, Arai, Hiroshi, Hiroshi Tsutsumi, Tetsuo Narumi, Wataru Nomura, Naoki Yamamoto, Pommier, Yves, Atsushi Komano, Hirokazu Tamamura. Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products: Structure-Activity Relationship Studies, Bioorganic & Medicinal Chemistry, Vol. 18, No. 18, pp. 6771-6775, Sept. 2010.  公式リンク  
  
• Shintaro Suzuki, Urano, Emiko, Chie Hashimoto, Hiroshi Tsutsumi, Toru Nakahara, Tomohiro Tanaka, Yuta Nakanishi, Maddali, Kasthuraiah, Han, Yan, Hamatake, Makiko, Miyauchi, Kosuke, Pommie, Yves, Beutler, John A., Sugiura, Wataru, Fuji, Hideyoshi, Hoshino, Tyuji, Kyoko Itotani, Wataru Nomura, Tetsuo Narumi, Naoki Yamamoto, Atsushi Komano, Hirokazu Tamamura. Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products, Journal of Medicinal Chemistry, Vol. 53, No. 14, pp. 5356-5360, July 2010.  公式リンク  
  
• Hiroshi Tsutsumi, Wataru Nomura, Seiichiro Abe, Tomoaki Mino, Akemi Masuda, Nami Ohashi, Tomohiro Tanaka, Kenji Ohba, Naoki Yamamoto, Kazunari Akiyoshi, Hirokazu Tamamura. Fluorogenically Active Leucine Zipper Peptides as Tag-Probe Pairs for Protein Imaging in Living Cells, Angewandte Chemie-International Edition, Vol. 48, No. 48, pp. 9164-9166, Nov. 2009.  公式リンク  
  
• Tomohiro Tanaka, Hiroshi Tsutsumi, Wataru Nomura, Yasuaki Tanabe, Nami Ohashi, Esaka, Ai, Chihiro Ochiai, Sato, Jun, Kyoko Itotani, Tsutomu Murakami, Kenji Ohba, Naoki Yamamoto, Nobutaka Fujii, Hirokazu Tamamura. Structure-Activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold: Identification of the New Pharmacophore, Organic & Biomolecular Chemistry, Vol. 6, No. 23, pp. 4374-4377, Oct. 2008.  公式リンク  
  
• Wataru Nomura, Yasuaki Tanabe, Hiroshi Tsutsumi, Tomohiro Tanaka, Kenji Ohba, Naoki Yamamoto, Hirokazu Tamamura. Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening, Bioconjugate Chemistry, Vol. 19, No. 9, pp. 1917-1920, Aug. 2008.  公式リンク  
  
• Hirokazu Tamamura, Tomohiro Tanaka, Hiroshi Tsutsumi, Nemoto, Koji, Mizokami, Satoko, Nami Ohashi, Shinya Oishi, Nobutaka Fujii. Versatile Use of Acid-Catalyzed Ring-opening of β-Aziridinyl-α, β-Enoates to Stereoselective Synthesis of Peptidomimetics, Tetrahedron, Vol. 63, No. 37, pp. 9243-9254, Sept. 2007.  公式リンク  
  
• Hirokazu Tamamura, Hiroshi Tsutsumi, Hiroyuki Masuno, Ogawa, T., Kenichi Hiramatsu, Araki, T., Ueda, S., Shinya Oishi, Esaka, A., Wang, Z., Peiper, S. C., Trent, J. O., Nobutaka Fujii. Synthesis and Biological Evaluation of CXCR4 Antagonists as Pharmaceutical Agents, Journal of Peptide Science, Vol. 12, No. S1, pp. 282, Sept. 2006.  公式リンク  
  
• Hirokazu Tamamura, Hiroshi Tsutsumi, Nobutaka Fujii. The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases, Mini-Reviews in Medicinal Chemistry, Vol. 6, No. 9, pp. 989-995, Sept. 2006.  公式リンク  
  
• Hirokazu Tamamura, Akio Ojida, Ogawa, Teppei, Hiroshi Tsutsumi, Hiroyuki Masuno, Nakashima, Hideki, Naoki Yamamoto, Iraru Hamachi, Nobutaka Fujii. Identification of a New Class of Low Molecular Weight Antagonists against the Chemokine Receptor CXCR4 Having the Dipicolylamine-Zinc(II) Complex Structure, Journal of Medicinal Chemistry, Vol. 49, No. 11, pp. 3412-3415, June 2006.  公式リンク  
  
• Hirokazu Tamamura, Hiroshi Tsutsumi, Hiroyuki Masuno, Mizokami, Satoko, Kenichi Hiramatsu, Wang, Zixuan, Trent, John O., Nakashima, Hideki, Naoki Yamamoto, Peiper, Stephen C., Nobutaka Fujii. Development of Linear Type of Low Molecular Weight CXCR4 Antagonists Based on T140 Analogs, Organic & Biomolecular Chemistry, Vol. 4, No. 12, pp. 2354-2357, May 2006.  公式リンク  
  
• Hirokazu Tamamura, Esaka, A, Ogawa, T, Araki, T, Ueda, S, Wang, ZX, Trent, JO, Hiroshi Tsutsumi, Hiroyuki Masuno, Nakashima, H, Naoki Yamamoto, Peiper, SC, Akira Otaka, Nobutaka Fujii. Structure-Activity Relationship Studies on CXCR4 Antagonists Having Cyclic Pentapeptide Scaffolds, Organic & Biomolecular Chemistry, Vol. 3, No. 24, pp. 4392-4394, Nov. 2005.  公式リンク  
  

その他の論文・著書など

• Hirokazu Tamamura, Hiroshi Tsutsumi, Wataru Nomura, Tomohiro Tanaka, Nobutaka Fujii. A Future Perspective on the Development of Chemokine Receptor CXCR4 Antagonists, Expert Opinion on Drug Discovery, Vol. 3, No. 10, pp. 1155-1166, Sept. 2008.  公式リンク  
  
• Hirokazu Tamamura, Hiroshi Tsutsumi, Wataru Nomura, Nobutaka Fujii. Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing, Perspectives in medicinal chemistry, Vol. 2, pp. 1-9, Jan. 2008.  公式リンク  
  
• Hiroshi Tsutsumi, Tomohiro Tanaka, Nami Ohashi, Hiroyuki Masuno, Hirokazu Tamamura, Kenichi Hiramatsu, Araki, Takanobu, Ueda, Satoshi, Shinya Oishi, Nobutaka Fujii. Therapeutic Potential of the Chemokine Receptor CXCR4 Antagonists as Multifunctional Agents, Biopolymers, Vol. 88, No. 2, pp. 279-289, Mar. 2007.  公式リンク  
  
• Hiroshi Tsutsumi, Hirokazu Tamamura, Nobutaka Fujii. Inhibitors of the Chemokine Receptor CXCR4. Chemotherapy of AIDS, Metastatic Cancer, Leukemia and Rheumatoid Arthritis, Letters in Drug Design & Discovery, Vol. 4, No. 1, pp. 20-26, Jan. 2007.  公式リンク  
  
• Hirokazu Tamamura, Hiroshi Tsutsumi, Hiroyuki Masuno, Nobutaka Fujii. Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetra- and Pentapeptide-Scaffolds towards the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis, Current Medicinal Chemistry, Vol. 14, No. 1, pp. 93-102, Jan. 2007.  公式リンク  
  
• Hirokazu Tamamura, Hiroshi Tsutsumi. Specific Probes for Chemokine Receptors, Chemistry & Biology, Vol. 13, No. 1, pp. 8-10, Jan. 2006.  公式リンク  
  

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